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Factories without walls: The molecular architecture and functions of non-membrane organelles in small RNA-guided genome protection
Shinichi Kawaguchi, Wakana Isshiki, Toshie Kai
Biochimica et Biophysica Acta (BBA) - General Subjects Vol. 1869 No. 7 p. 130811-130811 2025年6月 研究論文(学術雑誌)
出版者・発行元:Elsevier BV
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In silico screening by AlphaFold2 program revealed the potential binding partners of nuage-localizing proteins and piRNA-related proteins
Kawaguchi Shinichi, Xu Xin, Soga Takashi, Yamaguchi Kenta, Kawasaki Ryuuya, Shimouchi Ryota, Date Susumu, Kai Toshie
eLife 2025年4月22日
出版者・発行元:eLife Sciences Publications, Ltd
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HemK2 functions for sufficient protein synthesis and RNA stability through eRF1 methylation during Drosophila oogenesis
Fengmei Xu, Ritsuko Suyama, Toshifumi Inada, Shinichi Kawaguchi, Toshie Kai
Development Vol. 151 No. 14 2024年7月15日 研究論文(学術雑誌)
出版者・発行元:The Company of Biologists
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Tejas functions as a core component in nuage assembly and precursor processing in Drosophila piRNA biogenesis.
Yuxuan Lin, Ritsuko Suyama, Shinichi Kawaguchi, Taichiro Iki, Toshie Kai
The Journal of cell biology Vol. 222 No. 10 2023年10月2日 研究論文(学術雑誌)
出版者・発行元:Cold Spring Harbor Laboratory
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A pathway to produce non-coding piRNAs from endogenous protein-coding regions supports Drosophila spermatogenesis
Taichiro Iki, Shinichi Kawaguchi, Toshie Kai
Science advances Vol. 9 No. 29 2022年10月3日 研究論文(学術雑誌)
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The Tudor Domain-Containing Protein, Kotsubu (CG9925), Localizes to the Nuage and Functions in piRNA Biogenesis in D. melanogaster.
Lin-Xenia Lim, Wakana Isshiki, Taichiro Iki, Shinichi Kawaguchi, Toshie Kai
Frontiers in molecular biosciences Vol. 9 p. 818302-818302 2022年 研究論文(学術雑誌)
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Drosophila MARF1 ensures proper oocyte maturation by regulating nanos expression.
Shinichi Kawaguchi, Mizuki Ueki, Toshie Kai
PloS one Vol. 15 No. 4 2020年
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Cell biology. Sensing ER stress.
Shinichi Kawaguchi, Davis T W Ng
Science (New York, N.Y.) Vol. 333 No. 6051 p. 1830-1 2011年9月30日 研究論文(学術雑誌)
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Interplay of substrate retention and export signals in endoplasmic reticulum quality control.
Shinichi Kawaguchi, Chia-Ling Hsu, Davis T W Ng
PloS one Vol. 5 No. 11 2010年11月24日 研究論文(学術雑誌)
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SnapShot: ER-associated protein degradation pathways.
Shinichi Kawaguchi, Davis T W Ng
Cell Vol. 129 No. 6 p. 1230-1230 2007年6月15日 研究論文(学術雑誌)
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Characterization of a Drosophila centrosome protein CP309 that shares homology with Kendrin and CG-NAP.
Shin-ichi Kawaguchi, Yixian Zheng
Molecular biology of the cell Vol. 15 No. 1 p. 37-45 2004年1月 研究論文(学術雑誌)
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The crystal structure of the ttCsaA protein: an export-related chaperone from Thermus thermophilus.
S Kawaguchi, J Müller, D Linde, S Kuramitsu, T Shibata, Y Inoue, D G Vassylyev, S Yokoyama
The EMBO journal Vol. 20 No. 3 p. 562-9 2001年2月1日 研究論文(学術雑誌)
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Thermodynamics and molecular simulation analysis of hydrophobic substrate recognition by aminotransferases.
S i Kawaguchi, S Kuramitsu
The Journal of biological chemistry Vol. 273 No. 29 p. 18353-64 1998年7月17日 研究論文(学術雑誌)
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Enzyme flexibility: a new concept in recognition of hydrophobic substrates.
S Kawaguchi, Y Nobe, J Yasuoka, T Wakamiya, S Kusumoto, S Kuramitsu
Journal of biochemistry Vol. 122 No. 1 p. 55-63 1997年7月 研究論文(学術雑誌)
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Separation of heat-stable proteins from Thermus thermophilus HB8 by two-dimensional electrophoresis.
S Kawaguchi, S Kuramitsu
Electrophoresis Vol. 16 No. 6 p. 1060-6 1995年6月 研究論文(学術雑誌)
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Homologous ligation: a novel cloning method.
S Kawaguchi, S Kuramitsu
Trends in genetics : TIG Vol. 10 No. 12 p. 420-420 1994年12月 研究論文(学術雑誌)
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[Mechanism of enzyme reaction].
S Kawaguchi, S Kuramitsu
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme Vol. 39 No. 7 p. 1083-90 1994年5月 研究論文(学術雑誌)
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Pathogenesis and potential therapeutic targets of trichorhinophalangeal syndrome; lessons obtained from animal studies.
Naoya Saeki, Rinna Kanai, Sayuri Tatsuta, Shinichi Kawaguchi, Masatsune Itoh, Shinsuke Ohba, Makoto Abe
Developmental dynamics : an official publication of the American Association of Anatomists 2025年9月25日 研究論文(学術雑誌)
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Structural comparison between the open and closed forms of citrate synthase from Thermus thermophilus HB8.
Eiji Kanamori, Shin-Ichi Kawaguchi, Seiki Kuramitsu, Tsutomu Kouyama, Midori Murakami
Biophysics and physicobiology Vol. 12 p. 47-56 2015年 研究論文(学術雑誌)
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Biosynthetic mode can determine the mechanism of protein quality control.
Rupali Prasad, Shinichi Kawaguchi, Davis T W Ng
Biochemical and biophysical research communications Vol. 425 No. 3 p. 689-95 2012年8月31日 研究論文(学術雑誌)
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A nucleus-based quality control mechanism for cytosolic proteins.
Rupali Prasad, Shinichi Kawaguchi, Davis T W Ng
Molecular biology of the cell Vol. 21 No. 13 p. 2117-27 2010年7月1日 研究論文(学術雑誌)
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Regulation of microtubule assembly and organization in mitosis by the AAA+ ATPase Pontin.
Daniel Ducat, Shin-Ichi Kawaguchi, Hongbin Liu, John R Yates 3rd, Yixian Zheng
Molecular biology of the cell Vol. 19 No. 7 p. 3097-110 2008年7月 研究論文(学術雑誌)
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The EDEM and Yos9p families of lectin-like ERAD factors.
Kazue Kanehara, Shinichi Kawaguchi, Davis T W Ng
Seminars in cell & developmental biology Vol. 18 No. 6 p. 743-50 2007年12月 研究論文(学術雑誌)
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Crystal structure of the conserved protein TTHA0727 from Thermus thermophilus HB8 at 1.9 A resolution: A CMD family member distinct from carboxymuconolactone decarboxylase (CMD) and AhpD.
Kaori Ito, Ryoichi Arai, Emiko Fusatomi, Tomomi Kamo-Uchikubo, Shin-Ichi Kawaguchi, Ryogo Akasaka, Takaho Terada, Seiki Kuramitsu, Mikako Shirouzu, Shigeyuki Yokoyama
Protein science : a publication of the Protein Society Vol. 15 No. 5 p. 1187-92 2006年5月 研究論文(学術雑誌)
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Expression and purification of recombinant human histones.
Yoshinori Tanaka, Maki Tawaramoto-Sasanuma, Shinichi Kawaguchi, Tsutomu Ohta, Kinya Yoda, Hitoshi Kurumizaka, Shigeyuki Yokoyama
Methods (San Diego, Calif.) Vol. 33 No. 1 p. 3-11 2004年5月 研究論文(学術雑誌)
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Crystal structure of the CENP-B protein-DNA complex: the DNA-binding domains of CENP-B induce kinks in the CENP-B box DNA
Y Tanaka, O Nureki, H Kurumizaka, S Fukai, S Kawaguchi, M Ikuta, J Iwahara, T Okazaki, S Yokoyama
EMBO JOURNAL Vol. 20 No. 23 p. 6612-6618 2001年12月 研究論文(学術雑誌)
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Substrate recognition mechanism of thermophilic dual-substrate enzyme.
H Ura, T Nakai, S I Kawaguchi, I Miyahara, K Hirotsu, S Kuramitsu
Journal of biochemistry Vol. 130 No. 1 p. 89-98 2001年7月 研究論文(学術雑誌)
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Structure of the EMAPII domain of human aminoacyl-tRNA synthetase complex reveals evolutionary dimer mimicry.
L Renault, P Kerjan, S Pasqualato, J Ménétrey, J C Robinson, S Kawaguchi, D G Vassylyev, S Yokoyama, M Mirande, J Cherfils
The EMBO journal Vol. 20 No. 3 p. 570-8 2001年2月1日 研究論文(学術雑誌)
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1P019高度好熱菌Thermus thermophilus HB8由来クエン酸シンターゼリガンド複合体のX線結晶構造解析
村上 緑, 金森 英司, 河口 真一, 倉光 成紀, 横山 茂之, 神山 勉
生物物理 Vol. 41 2001年
出版者・発行元:一般社団法人 日本生物物理学会
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Free energy requirement for domain movement of an enzyme.
J Ishijima, T Nakai, S Kawaguchi, K Hirotsu, S Kuramitsu
The Journal of biological chemistry Vol. 275 No. 25 p. 18939-45 2000年6月23日 研究論文(学術雑誌)
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The molecular structure of hyperthermostable aromatic aminotransferase with novel substrate specificity from Pyrococcus horikoshii.
I Matsui, E Matsui, Y Sakai, H Kikuchi, Y Kawarabayasi, H Ura, S Kawaguchi, S Kuramitsu, K Harata
The Journal of biological chemistry Vol. 275 No. 7 p. 4871-9 2000年2月18日 研究論文(学術雑誌)
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Structural genomics projects in Japan.
S Yokoyama, Y Matsuo, H Hirota, T Kigawa, M Shirouzu, Y Kuroda, H Kurumizaka, S Kawaguchi, Y Ito, T Shibata, M Kainosho, Y Nishimura, Y Inoue, S Kuramitsu
Progress in biophysics and molecular biology Vol. 73 No. 5 p. 363-76 2000年 研究論文(学術雑誌)
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Structure of Thermus thermophilus HB8 aspartate aminotransferase and its complex with maleate.
T Nakai, K Okada, S Akutsu, I Miyahara, S Kawaguchi, R Kato, S Kuramitsu, K Hirotsu
Biochemistry Vol. 38 No. 8 p. 2413-24 1999年2月23日 研究論文(学術雑誌)
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The novel substrate recognition mechanism utilized by aspartate aminotransferase of the extreme thermophile Thermus thermophilus HB8.
Y Nobe, S Kawaguchi, H Ura, T Nakai, K Hirotsu, R Kato, S Kuramitsu
The Journal of biological chemistry Vol. 273 No. 45 p. 29554-64 1998年11月6日 研究論文(学術雑誌)
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Crystallization and preliminary X-ray characterization of aspartate aminotransferase from an extreme thermophile, Thermus thermophilus HB8.
T Nakai, K Okada, S Kawaguchi, R Kato, S Kuramitsu, K Hirotsu
Acta crystallographica. Section D, Biological crystallography Vol. 54 No. Pt 5 p. 1032-4 1998年9月1日 研究論文(学術雑誌)
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Cloning and characterization of the uvrD gene from an extremely thermophilic bacterium, Thermus thermophilus HB8.
Y Hiramatsu, R Kato, S Kawaguchi, S Kuramitsu
Gene Vol. 199 No. 1-2 p. 77-82 1997年10月15日 研究論文(学術雑誌)
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Construction of aminotransferase chimeras and analysis of their substrate specificity.
K Miyazawa, S Kawaguchi, A Okamoto, R Kato, T Ogawa, S Kuramitsu
Journal of biochemistry Vol. 115 No. 3 p. 568-77 1994年3月 研究論文(学術雑誌)