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Factories without walls: The molecular architecture and functions of non-membrane organelles in small RNA-guided genome protection
Shinichi Kawaguchi, Wakana Isshiki, Toshie Kai
Biochimica et Biophysica Acta (BBA) - General Subjects Vol. 1869 No. 7 p. 130811-130811 2025/06 Research paper (scientific journal)
Publisher: Elsevier BV
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In silico screening by AlphaFold2 program revealed the potential binding partners of nuage-localizing proteins and piRNA-related proteins
Kawaguchi Shinichi, Xu Xin, Soga Takashi, Yamaguchi Kenta, Kawasaki Ryuuya, Shimouchi Ryota, Date Susumu, Kai Toshie
eLife 2025/04/22
Publisher: eLife Sciences Publications, Ltd
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HemK2 functions for sufficient protein synthesis and RNA stability through eRF1 methylation during Drosophila oogenesis
Fengmei Xu, Ritsuko Suyama, Toshifumi Inada, Shinichi Kawaguchi, Toshie Kai
Development Vol. 151 No. 14 2024/07/15 Research paper (scientific journal)
Publisher: The Company of Biologists
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Tejas functions as a core component in nuage assembly and precursor processing in Drosophila piRNA biogenesis.
Yuxuan Lin, Ritsuko Suyama, Shinichi Kawaguchi, Taichiro Iki, Toshie Kai
The Journal of cell biology Vol. 222 No. 10 2023/10/02 Research paper (scientific journal)
Publisher: Cold Spring Harbor Laboratory
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A pathway to produce non-coding piRNAs from endogenous protein-coding regions supports Drosophila spermatogenesis
Taichiro Iki, Shinichi Kawaguchi, Toshie Kai
Science advances Vol. 9 No. 29 2022/10/03 Research paper (scientific journal)
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The Tudor Domain-Containing Protein, Kotsubu (CG9925), Localizes to the Nuage and Functions in piRNA Biogenesis in D. melanogaster.
Lin-Xenia Lim, Wakana Isshiki, Taichiro Iki, Shinichi Kawaguchi, Toshie Kai
Frontiers in molecular biosciences Vol. 9 p. 818302-818302 2022 Research paper (scientific journal)
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Drosophila MARF1 ensures proper oocyte maturation by regulating nanos expression.
Shinichi Kawaguchi, Mizuki Ueki, Toshie Kai
PloS one Vol. 15 No. 4 2020
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Cell biology. Sensing ER stress.
Shinichi Kawaguchi, Davis T W Ng
Science (New York, N.Y.) Vol. 333 No. 6051 p. 1830-1 2011/09/30 Research paper (scientific journal)
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Interplay of substrate retention and export signals in endoplasmic reticulum quality control.
Shinichi Kawaguchi, Chia-Ling Hsu, Davis T W Ng
PloS one Vol. 5 No. 11 2010/11/24 Research paper (scientific journal)
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SnapShot: ER-associated protein degradation pathways.
Shinichi Kawaguchi, Davis T W Ng
Cell Vol. 129 No. 6 p. 1230-1230 2007/06/15 Research paper (scientific journal)
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Characterization of a Drosophila centrosome protein CP309 that shares homology with Kendrin and CG-NAP.
Shin-ichi Kawaguchi, Yixian Zheng
Molecular biology of the cell Vol. 15 No. 1 p. 37-45 2004/01 Research paper (scientific journal)
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The crystal structure of the ttCsaA protein: an export-related chaperone from Thermus thermophilus.
S Kawaguchi, J Müller, D Linde, S Kuramitsu, T Shibata, Y Inoue, D G Vassylyev, S Yokoyama
The EMBO journal Vol. 20 No. 3 p. 562-9 2001/02/01 Research paper (scientific journal)
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Thermodynamics and molecular simulation analysis of hydrophobic substrate recognition by aminotransferases.
S i Kawaguchi, S Kuramitsu
The Journal of biological chemistry Vol. 273 No. 29 p. 18353-64 1998/07/17 Research paper (scientific journal)
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Enzyme flexibility: a new concept in recognition of hydrophobic substrates.
S Kawaguchi, Y Nobe, J Yasuoka, T Wakamiya, S Kusumoto, S Kuramitsu
Journal of biochemistry Vol. 122 No. 1 p. 55-63 1997/07 Research paper (scientific journal)
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Separation of heat-stable proteins from Thermus thermophilus HB8 by two-dimensional electrophoresis.
S Kawaguchi, S Kuramitsu
Electrophoresis Vol. 16 No. 6 p. 1060-6 1995/06 Research paper (scientific journal)
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Homologous ligation: a novel cloning method.
S Kawaguchi, S Kuramitsu
Trends in genetics : TIG Vol. 10 No. 12 p. 420-420 1994/12 Research paper (scientific journal)
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[Mechanism of enzyme reaction].
S Kawaguchi, S Kuramitsu
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme Vol. 39 No. 7 p. 1083-90 1994/05 Research paper (scientific journal)
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Pathogenesis and potential therapeutic targets of trichorhinophalangeal syndrome; lessons obtained from animal studies.
Naoya Saeki, Rinna Kanai, Sayuri Tatsuta, Shinichi Kawaguchi, Masatsune Itoh, Shinsuke Ohba, Makoto Abe
Developmental dynamics : an official publication of the American Association of Anatomists 2025/09/25 Research paper (scientific journal)
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Structural comparison between the open and closed forms of citrate synthase from Thermus thermophilus HB8.
Eiji Kanamori, Shin-Ichi Kawaguchi, Seiki Kuramitsu, Tsutomu Kouyama, Midori Murakami
Biophysics and physicobiology Vol. 12 p. 47-56 2015 Research paper (scientific journal)
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Biosynthetic mode can determine the mechanism of protein quality control.
Rupali Prasad, Shinichi Kawaguchi, Davis T W Ng
Biochemical and biophysical research communications Vol. 425 No. 3 p. 689-95 2012/08/31 Research paper (scientific journal)
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A nucleus-based quality control mechanism for cytosolic proteins.
Rupali Prasad, Shinichi Kawaguchi, Davis T W Ng
Molecular biology of the cell Vol. 21 No. 13 p. 2117-27 2010/07/01 Research paper (scientific journal)
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Regulation of microtubule assembly and organization in mitosis by the AAA+ ATPase Pontin.
Daniel Ducat, Shin-Ichi Kawaguchi, Hongbin Liu, John R Yates 3rd, Yixian Zheng
Molecular biology of the cell Vol. 19 No. 7 p. 3097-110 2008/07 Research paper (scientific journal)
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The EDEM and Yos9p families of lectin-like ERAD factors.
Kazue Kanehara, Shinichi Kawaguchi, Davis T W Ng
Seminars in cell & developmental biology Vol. 18 No. 6 p. 743-50 2007/12 Research paper (scientific journal)
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Crystal structure of the conserved protein TTHA0727 from Thermus thermophilus HB8 at 1.9 A resolution: A CMD family member distinct from carboxymuconolactone decarboxylase (CMD) and AhpD.
Kaori Ito, Ryoichi Arai, Emiko Fusatomi, Tomomi Kamo-Uchikubo, Shin-Ichi Kawaguchi, Ryogo Akasaka, Takaho Terada, Seiki Kuramitsu, Mikako Shirouzu, Shigeyuki Yokoyama
Protein science : a publication of the Protein Society Vol. 15 No. 5 p. 1187-92 2006/05 Research paper (scientific journal)
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Expression and purification of recombinant human histones.
Yoshinori Tanaka, Maki Tawaramoto-Sasanuma, Shinichi Kawaguchi, Tsutomu Ohta, Kinya Yoda, Hitoshi Kurumizaka, Shigeyuki Yokoyama
Methods (San Diego, Calif.) Vol. 33 No. 1 p. 3-11 2004/05 Research paper (scientific journal)
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Crystal structure of the CENP-B protein-DNA complex: the DNA-binding domains of CENP-B induce kinks in the CENP-B box DNA
Y Tanaka, O Nureki, H Kurumizaka, S Fukai, S Kawaguchi, M Ikuta, J Iwahara, T Okazaki, S Yokoyama
EMBO JOURNAL Vol. 20 No. 23 p. 6612-6618 2001/12 Research paper (scientific journal)
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Substrate recognition mechanism of thermophilic dual-substrate enzyme.
H Ura, T Nakai, S I Kawaguchi, I Miyahara, K Hirotsu, S Kuramitsu
Journal of biochemistry Vol. 130 No. 1 p. 89-98 2001/07 Research paper (scientific journal)
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Structure of the EMAPII domain of human aminoacyl-tRNA synthetase complex reveals evolutionary dimer mimicry.
L Renault, P Kerjan, S Pasqualato, J Ménétrey, J C Robinson, S Kawaguchi, D G Vassylyev, S Yokoyama, M Mirande, J Cherfils
The EMBO journal Vol. 20 No. 3 p. 570-8 2001/02/01 Research paper (scientific journal)
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Crystal structure of citrate synthase closed form from Thermus thermophilus HB8
Murakami M., Kanamori E., Kawaguchi S., Kuramitsu S., Yokoyama S., Kouyama T.
Seibutsu Butsuri Vol. 41 2001
Publisher: The Biophysical Society of Japan General Incorporated Association
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Free energy requirement for domain movement of an enzyme.
J Ishijima, T Nakai, S Kawaguchi, K Hirotsu, S Kuramitsu
The Journal of biological chemistry Vol. 275 No. 25 p. 18939-45 2000/06/23 Research paper (scientific journal)
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The molecular structure of hyperthermostable aromatic aminotransferase with novel substrate specificity from Pyrococcus horikoshii.
I Matsui, E Matsui, Y Sakai, H Kikuchi, Y Kawarabayasi, H Ura, S Kawaguchi, S Kuramitsu, K Harata
The Journal of biological chemistry Vol. 275 No. 7 p. 4871-9 2000/02/18 Research paper (scientific journal)
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Structural genomics projects in Japan.
S Yokoyama, Y Matsuo, H Hirota, T Kigawa, M Shirouzu, Y Kuroda, H Kurumizaka, S Kawaguchi, Y Ito, T Shibata, M Kainosho, Y Nishimura, Y Inoue, S Kuramitsu
Progress in biophysics and molecular biology Vol. 73 No. 5 p. 363-76 2000 Research paper (scientific journal)
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Structure of Thermus thermophilus HB8 aspartate aminotransferase and its complex with maleate.
T Nakai, K Okada, S Akutsu, I Miyahara, S Kawaguchi, R Kato, S Kuramitsu, K Hirotsu
Biochemistry Vol. 38 No. 8 p. 2413-24 1999/02/23 Research paper (scientific journal)
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The novel substrate recognition mechanism utilized by aspartate aminotransferase of the extreme thermophile Thermus thermophilus HB8.
Y Nobe, S Kawaguchi, H Ura, T Nakai, K Hirotsu, R Kato, S Kuramitsu
The Journal of biological chemistry Vol. 273 No. 45 p. 29554-64 1998/11/06 Research paper (scientific journal)
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Crystallization and preliminary X-ray characterization of aspartate aminotransferase from an extreme thermophile, Thermus thermophilus HB8.
T Nakai, K Okada, S Kawaguchi, R Kato, S Kuramitsu, K Hirotsu
Acta crystallographica. Section D, Biological crystallography Vol. 54 No. Pt 5 p. 1032-4 1998/09/01 Research paper (scientific journal)
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Cloning and characterization of the uvrD gene from an extremely thermophilic bacterium, Thermus thermophilus HB8.
Y Hiramatsu, R Kato, S Kawaguchi, S Kuramitsu
Gene Vol. 199 No. 1-2 p. 77-82 1997/10/15 Research paper (scientific journal)
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Construction of aminotransferase chimeras and analysis of their substrate specificity.
K Miyazawa, S Kawaguchi, A Okamoto, R Kato, T Ogawa, S Kuramitsu
Journal of biochemistry Vol. 115 No. 3 p. 568-77 1994/03 Research paper (scientific journal)
