EN

基本情報

研究

社会活動

その他の活動

坂口 志文

Sakaguchi Shimon

免疫学フロンティア研究センター,特任教授(常勤)

学歴

  • ~ 1976年,京都大学,医学部,医学
  • ~ 1976年,京都大学,Faculty of Medicine

研究内容・専門分野

  • ライフサイエンス,免疫学
  • ライフサイエンス,実験病理学

所属学会

  • 日本リウマチ学会
  • アメリカ免疫学会(American Association of Immunologists)
  • 日本免疫学会

論文

  • Proenkephalin+ regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function.,Hiroaki Shime,Mizuyu Odanaka,Makoto Tsuiji,Takuma Matoba,Masaki Imai,Yoshiaki Yasumizu,Ryuta Uraki,Kiyoshi Minohara,Maiko Watanabe,Anthony John Bonito,Hidehiro Fukuyama,Naganari Ohkura,Shimon Sakaguchi,Akimichi Morita,Sayuri Yamazaki,Proceedings of the National Academy of Sciences of the United States of America,2020年08月07日,研究論文(学術雑誌)
  • Dynamics of effector and naïve Regulatory T cells throughout pregnancy.,Naoya Shigeta,Keiichi Kumasawa,Atsushi Tanaka,James Badger Wing,Hitomi Nakamura,Shimon Sakaguchi,Tadashi Kimura,Journal of reproductive immunology,Vol. 140,p. 103135-103135,2020年08月,研究論文(学術雑誌)
  • Regulatory T Cell-Specific Epigenomic Region Variants Are a Key Determinant of Susceptibility to Common Autoimmune Diseases.,Naganari Ohkura,Yoshiaki Yasumizu,Yohko Kitagawa,Atsushi Tanaka,Yamami Nakamura,Daisuke Motooka,Shota Nakamura,Yukinori Okada,Shimon Sakaguchi,Immunity,Vol. 52,No. 6,p. 1119-1132,2020年06月16日,研究論文(学術雑誌)
  • Impaired T cell receptor signaling and development of T cell-mediated autoimmune arthritis.,Yusuke Takeuchi,Keiji Hirota,Shimon Sakaguchi,Immunological reviews,Vol. 294,No. 1,p. 164-176,2020年03月
  • Tyrosine kinase inhibitor imatinib augments tumor immunity by depleting effector regulatory T cells.,Atsushi Tanaka,Hiroyoshi Nishikawa,Shinsuke Noguchi,Daisuke Sugiyama,Hiromasa Morikawa,Yoshiko Takeuchi,Danbee Ha,Naoya Shigeta,Toshio Kitawaki,Yuka Maeda,Takuro Saito,Yoshinori Shinohara,Yoshihiro Kameoka,Keiko Iwaisako,Fumihiko Monma,Kohshi Ohishi,Julia Karbach,Elke Jäger,Kenichi Sawada,Naoyuki Katayama,Naoto Takahashi,Shimon Sakaguchi,The Journal of experimental medicine,Vol. 217,No. 2,2020年02月03日
  • Conversion of antigen-specific effector/memory T cells into Foxp3-expressing Treg cells by inhibition of CDK8/19.,Masahiko Akamatsu,Norihisa Mikami,Naganari Ohkura,Ryoji Kawakami,Yohko Kitagawa,Atsushi Sugimoto,Keiji Hirota,Naoto Nakamura,Satoru Ujihara,Toshio Kurosaki,Hisao Hamaguchi,Hironori Harada,Guliang Xia,Yoshiaki Morita,Ichiro Aramori,Shuh Narumiya,Shimon Sakaguchi,Science immunology,Vol. 4,No. 40,2019年10月25日
  • Dynamic Imprinting of the Treg Cell-Specific Epigenetic Signature in Developing Thymic Regulatory T Cells,Susanne Herppich,Aras Toker,Beate Pietzsch,Yohko Kitagawa,Naganari Ohkura,Takahisa Miyao,Stefan Floess,Shohei Hori,Shimon Sakaguchi,Jochen Huehn,Frontiers in Immunology,Frontiers Media SA,Vol. 10,2019年10月11日,研究論文(学術雑誌)
  • Strain-Specific Manifestation of Lupus-like Systemic Autoimmunity Caused by Zap70 Mutation.,Takashi Matsuo,Motomu Hashimoto,Shimon Sakaguchi,Noriko Sakaguchi,Yoshinaga Ito,Masaki Hikida,Tatsuaki Tsuruyama,Kaoru Sakai,Hideki Yokoi,Mirei Shirakashi,Masao Tanaka,Hiromu Ito,Hajime Yoshifuji,Koichiro Ohmura,Takao Fujii,Tsuneyo Mimori,Journal of immunology (Baltimore, Md. : 1950),Vol. 202,No. 11,p. 3161-3172,2019年06月01日,研究論文(学術雑誌)
  • PD-1+ regulatory T cells amplified by PD-1 blockade promote hyperprogression of cancer,Takahiro Kamada,Yosuke Togashi,Danbee Ha,Akinori Sasaki,Yoshiaki Nakamura,Eiichi Sato,Shota Fukuoka,Yasuko Tada,Atsushi Tanaka,Akihito Kawazoe,Takahiro Kinoshita,Kohei Shitara,Shimon Sakaguchi,Hiroyoshi Nishikawa,Proc Natl Acad Sci U S A,2019年04月
  • Innate Myeloid Cell Subset-Specific Gene Expression Patterns in the Human Colon are Altered in Crohn's Disease Patients.,Yuki Sekido,Yoshiaki Yasumizu,Junichi Nishimura,Hisako Kayama,Hiroshi Matsuno,Takayuki Ogino,Norikatsu Miyoshi,Hidekazu Takahashi,Naotsugu Haraguchi,Taishi Hata,Chu Matsuda,Yuichiro Doki,Masaki Mori,Kiyoshi Takeda,Naganari Ohkura,Shimon Sakaguchi,Tsunekazu Mizushima,Digestion,Vol. 99,No. 3,p. 194-204,2019年,研究論文(学術雑誌)
  • Autoimmune Th17 Cells Induced Synovial Stromal and Innate Lymphoid Cell Secretion of the Cytokine GM-CSF to Initiate and Augment Autoimmune Arthritis.,Keiji Hirota,Motomu Hashimoto,Yoshinaga Ito,Mayumi Matsuura,Hiromu Ito,Masao Tanaka,Hitomi Watanabe,Gen Kondoh,Atsushi Tanaka,Keiko Yasuda,Manfred Kopf,Alexandre J Potocnik,Brigitta Stockinger,Noriko Sakaguchi,Shimon Sakaguchi,Immunity,Vol. 48,No. 6,p. 1220-1232,2018年06月19日,研究論文(学術雑誌)
  • Preoperative metabolic tumor volume of intrahepatic cholangiocarcinoma measured by 18F-FDG-PET is associated with the KRAS mutation status and prognosis,Yoshinobu Ikeno,Satoru Seo,Keiko Iwaisako,Tomoaki Yoh,Yuji Nakamoto,Hiroaki Fuji,Kojiro Taura,Hideaki Okajima,Toshimi Kaido,Shimon Sakaguchi,Shinji Uemoto,Journal of Translational Medicine,BioMed Central Ltd.,Vol. 16,No. 1,2018年04月11日,研究論文(学術雑誌)
  • Selective cell capture and release using antibody-immobilized polymer-grafted surface,Tsuyoshi Kimura,Naoko Nakamura,Yoshihide Hashimoto,Shimon Sakaguchi,Shunsaku Kimura,Akio Kishida,Kobunshi Ronbunshu,Society of Polymer Science,Vol. 75,No. 2,p. 155-163,2018年03月01日,研究論文(学術雑誌)
  • Long-term Functioning of Allogeneic Islets in Subcutaneous Tissue Pretreated with a Novel Cyclic Peptide Without Immunosuppressive Medication,Rei Kuwabara,Masahide Hamaguchi,Takuya Fukuda,Hiroki Sakai,Makoto Inui,Shimon Sakaguchi,Hiroo Iwata,Transplantation,Lippincott Williams and Wilkins,Vol. 102,No. 3,p. 417-425,2018年03月01日,研究論文(学術雑誌)
  • Minimum information about T regulatory cells: A step toward reproducibility and standardization,Anke Fuchs,Mateusz Gliwinski,Nathali Grageda,Rachel Spiering,Abul K. Abbas,Silke Appel,Rosa Bacchetta,Manuela Battaglia,David Berglund,Bruce Blazar,Jeffrey A. Bluestone,Martin Bornhäuser,Anja ten Brinke,Todd M. Brusko,Nathalie Cools,Maria Cristina Cuturi,Edward Geissler,Nick Giannoukakis,Karolina Golab,David A. Hafler,S. Marieke van Ham,Joanna Hester,Keli Hippen,Mauro Di Ianni,Natasa Ilic,John Isaacs,Fadi Issa,Dorota Iwaszkiewicz-Grzes,Elmar Jaeckel,Irma Joosten,David Klatzmann,Hans Koenen,Cees van Kooten,Olle Korsgren,Karsten Kretschmer,Megan Levings,Natalia Maria Marek-Trzonkowska,Marc Martinez-Llordella,Djordje Miljkovic,Kingston H.G. Mills,Joana P. Miranda,Ciriaco A. Piccirillo,Amy L. Putnam,Thomas Ritter,Maria Grazia Roncarolo,Shimon Sakaguchi,Silvia Sánchez-Ramón,Birgit Sawitzki,Ljiljana Sofronic-Milosavljevic,Megan Sykes,Qizhi Tang,Marta Vives-Pi,Herman Waldmann,Piotr Witkowski,Kathryn J. Wood,Silvia Gregori,Catharien M.U. Hilkens,Giovanna Lombardi,Phillip Lord,Eva M. Martinez-Caceres,Piotr Trzonkowski,Frontiers in Immunology,Frontiers Media S.A.,Vol. 8,2018年01月15日,研究論文(学術雑誌)
  • Slc3a2 Mediates Branched-Chain Amino-Acid-Dependent Maintenance of Regulatory T Cells,Kayo Ikeda,Makoto Kinoshita,Hisako Kayama,Shushi Nagamori,Pornparn Kongpracha,Eiji Umemoto,Ryu Okumura,Takashi Kurakawa,Mari Murakami,Norihisa Mikami,Yasunori Shintani,Satoko Ueno,Ayatoshi Andou,Morihiro Ito,Hideki Tsumura,Koji Yasutomo,Keiichi Ozono,Seiji Takashima,Shimon Sakaguchi,Yoshikatsu Kanai,Kiyoshi Takeda,Cell Reports,Elsevier B.V.,Vol. 21,No. 7,p. 1824-1838,2017年11月14日,研究論文(学術雑誌)
  • Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment (vol 18, pg 173, 2017),Yohko Kitagawa,Naganari Ohkura,Yujiro Kidani,Alexis Vandenbon,Keiji Hirota,Ryoji Kawakami,Keiko Yasuda,Daisuke Motooka,Shota Nakamura,Motonari Kondo,Ichiro Taniuchi,Terumi Kohwi-Shigematsu,Shimon Sakaguchi,NATURE IMMUNOLOGY,NATURE PUBLISHING GROUP,Vol. 18,No. 11,p. 1270-1270,2017年11月
  • Guidelines for the use of flow cytometry and cell sorting in immunological studies,Andrea Cossarizza,Hyun-Dong Chang,Andreas Radbruch,Mübeccel Akdis,Immanuel Andrä,Francesco Annunziato,Petra Bacher,Vincenzo Barnaba,Luca Battistini,Wolfgang M. Bauer,Sabine Baumgart,Burkhard Becher,Wolfgang Beisker,Claudia Berek,Alfonso Blanco,Giovanna Borsellino,Philip E. Boulais,Ryan R. Brinkman,Martin Büscher,Dirk H. Busch,Timothy P. Bushnell,Xuetao Cao,Andrea Cavani,Pratip K. Chattopadhyay,Qingyu Cheng,Sue Chow,Mario Clerici,Anne Cooke,Antonio Cosma,Lorenzo Cosmi,Ana Cumano,Van Duc Dang,Derek Davies,Sara De Biasi,Genny Del Zotto,Silvia Della Bella,Paolo Dellabona,Günnur Deniz,Mark Dessing,Andreas Diefenbach,James Di Santo,Francesco Dieli,Andreas Dolf,Vera S. Donnenberg,Thomas Dörner,Götz R. A. Ehrhardt,Elmar Endl,Pablo Engel,Britta Engelhardt,Charlotte Esser,Bart Everts,Anita Dreher,Christine S. Falk,Todd A. Fehniger,Andrew Filby,Simon Fillatreau,Marie Follo,Irmgard Förster,John Foster,Gemma A. Foulds,Paul S. Frenette,David Galbraith,Natalio Garbi,Maria Dolores García-Godoy,Jens Geginat,Kamran Ghoreschi,Lara Gibellini,Christoph Goettlinger,Carl S. Goodyear,Andrea Gori,Jane Grogan,Mor Gross,Andreas Grützkau,Daryl Grummitt,Jonas Hahn,Quirin Hammer,Anja E. Hauser,David L. Haviland,David Hedley,Guadalupe Herrera,Martin Herrmann,Falk Hiepe,Tristan Holland,Pleun Hombrink,Jessica P. Houston,Bimba F. Hoyer,Bo Huang,Christopher A. Hunter,Anna Iannone,Hans-Martin Jäck,Beatriz Jávega,Stipan Jonjic,Kerstin Juelke,Steffen Jung,Toralf Kaiser,Tomas Kalina,Baerbel Keller,Srijit Khan,Deborah Kienhöfer,Thomas Kroneis,Désirée Kunkel,Christian Kurts,Pia Kvistborg,Joanne Lannigan,Olivier Lantz,Anis Larbi,Salome LeibundGut-Landmann,Michael D. Leipold,Megan K. Levings,Virginia Litwin,Yanling Liu,Michael Lohoff,Giovanna Lombardi,Lilly Lopez,Amy Lovett-Racke,Erik Lubberts,Burkhard Ludewig,Enrico Lugli,Holden T. Maecker,Glòria Martrus,Giuseppe Matarese,Christian Maueröder,Mairi McGrath,Iain McInnes,Henrik E. Mei,Fritz Melchers,Susanne Melzer,Dirk Mielenz,Kingston Mills,David Mirrer,Jenny Mjösberg,Jonni Moore,Barry Moran,Alessandro Moretta,Lorenzo Moretta,Tim R. Mosmann,Susann Müller,Werner Müller,Christian Münz,Gabriele Multhoff,Luis Enrique Munoz,Kenneth M. Murphy,Toshinori Nakayama,Milena Nasi,Christine Neudörfl,John Nolan,Sussan Nourshargh,José-Enrique O'Connor,Wenjun Ouyang,Annette Oxenius,Raghav Palankar,Isabel Panse,Pärt Peterson,Christian Peth,Jordi Petriz,Daisy Philips,Winfried Pickl,Silvia Piconese,Marcello Pinti,A. Graham Pockley,Malgorzata Justyna Podolska,Carlo Pucillo,Sally A. Quataert,Timothy R. D. J. Radstake,Bartek Rajwa,Jonathan A. Rebhahn,Diether Recktenwald,Ester B.M. Remmerswaal,Katy Rezvani,Laura G. Rico,J. Paul Robinson,Chiara Romagnani,Anna Rubartelli,Beate Ruckert,Jürgen Ruland,Shimon Sakaguchi,Francisco Sala-de-Oyanguren,Yvonne Samstag,Sharon Sanderson,Birgit Sawitzki,Alexander Scheffold,Matthias Schiemann,Frank Schildberg,Esther Schimisky,Stephan A. Schmid,Steffen Schmitt,Kilian Schober,Thomas Schüler,Axel Ronald Schulz,Ton Schumacher,Cristiano Scotta,T. Vincent Shankey,Anat Shemer,Anna-Katharina Simon,Josef Spidlen,Alan M. Stall,Regina Stark,Christina Stehle,Merle Stein,Tobit Steinmetz,Hannes Stockinger,Yousuke Takahama,Attila Tarnok,ZhiGang Tian,Gergely Toldi,Julia Tornack,Elisabetta Traggiai,Joe Trotter,Henning Ulrich,Marlous van der Braber,René A. W. van Lier,Marcello Veldhoen,Salvador Vento-Asturias,Paulo Vieira,David Voehringer,Hans-Dieter Volk,Konrad von Volkmann,Ari Waisman,Rachael Walker,Michael D. Ward,Klaus Warnatz,Sarah Warth,James V. Watson,Carsten Watzl,Leonie Wegener,Annika Wiedemann,Jürgen Wienands,Gerald Willimsky,James Wing,Peter Wurst,Liping Yu,Alice Yue,Qianjun Zhang,Yi Zhao,Susanne Ziegler,Jakob Zimmermann,European Journal of Immunology,Wiley-VCH Verlag,Vol. 47,No. 10,p. 1584-1797,2017年10月01日,研究論文(学術雑誌)
  • Lamtor1 Is Critically Required for CD4(+) T Cell Proliferation and Regulatory T Cell Suppressive Function,Takashi Hosokawa,Tetsuya Kimura,Shigeyuki Nada,Tatsusada Okuno,Daisuke Ito,Sujin Kang,Satoshi Nojima,Kazuya Yamashita,Takeshi Nakatani,Yoshitomo Hayama,Yasuhiro Kato,Yuhei Kinehara,Masayuki Nishide,Norihisa Mikami,Syohei Koyama,Hyota Takamatsu,Daisuke Okuzaki,Naganari Ohkura,Shimon Sakaguchi,Masato Okada,Atsushi Kumanogoh,JOURNAL OF IMMUNOLOGY,AMER ASSOC IMMUNOLOGISTS,Vol. 199,No. 6,p. 2008-2019,2017年09月,研究論文(学術雑誌)
  • FANTOM5 CAGE profiles of human and mouse samples.,Shuhei Noguchi,Takahiro Arakawa,Shiro Fukuda,Masaaki Furuno,Akira Hasegawa,Fumi Hori,Sachi Ishikawa-Kato,Kaoru Kaida,Ai Kaiho,Mutsumi Kanamori-Katayama,Tsugumi Kawashima,Miki Kojima,Atsutaka Kubosaki,Ri-Ichiroh Manabe,Mitsuyoshi Murata,Sayaka Nagao-Sato,Kenichi Nakazato,Noriko Ninomiya,Hiromi Nishiyori-Sueki,Shohei Noma,Eri Saijyo,Akiko Saka,Mizuho Sakai,Christophe Simon,Naoko Suzuki,Michihira Tagami,Shoko Watanabe,Shigehiro Yoshida,Peter Arner,Richard A Axton,Magda Babina,J Kenneth Baillie,Timothy C Barnett,Anthony G Beckhouse,Antje Blumenthal,Beatrice Bodega,Alessandro Bonetti,James Briggs,Frank Brombacher,Ailsa J Carlisle,Hans C Clevers,Carrie A Davis,Michael Detmar,Taeko Dohi,Albert S B Edge,Matthias Edinger,Anna Ehrlund,Karl Ekwall,Mitsuhiro Endoh,Hideki Enomoto,Afsaneh Eslami,Michela Fagiolini,Lynsey Fairbairn,Mary C Farach-Carson,Geoffrey J Faulkner,Carmelo Ferrai,Malcolm E Fisher,Lesley M Forrester,Rie Fujita,Jun-Ichi Furusawa,Teunis B Geijtenbeek,Thomas Gingeras,Daniel Goldowitz,Sven Guhl,Reto Guler,Stefano Gustincich,Thomas J Ha,Masahide Hamaguchi,Mitsuko Hara,Yuki Hasegawa,Meenhard Herlyn,Peter Heutink,Kelly J Hitchens,David A Hume,Tomokatsu Ikawa,Yuri Ishizu,Chieko Kai,Hiroshi Kawamoto,Yuki I Kawamura,Judith S Kempfle,Tony J Kenna,Juha Kere,Levon M Khachigian,Toshio Kitamura,Sarah Klein,S Peter Klinken,Alan J Knox,Soichi Kojima,Haruhiko Koseki,Shigeo Koyasu,Weonju Lee,Andreas Lennartsson,Alan Mackay-Sim,Niklas Mejhert,Yosuke Mizuno,Hiromasa Morikawa,Mitsuru Morimoto,Kazuyo Moro,Kelly J Morris,Hozumi Motohashi,Christine L Mummery,Yutaka Nakachi,Fumio Nakahara,Toshiyuki Nakamura,Yukio Nakamura,Tadasuke Nozaki,Soichi Ogishima,Naganari Ohkura,Hiroshi Ohno,Mitsuhiro Ohshima,Mariko Okada-Hatakeyama,Yasushi Okazaki,Valerio Orlando,Dmitry A Ovchinnikov,Robert Passier,Margaret Patrikakis,Ana Pombo,Swati Pradhan-Bhatt,Xian-Yang Qin,Michael Rehli,Patrizia Rizzu,Sugata Roy,Antti Sajantila,Shimon Sakaguchi,Hiroki Sato,Hironori Satoh,Suzana Savvi,Alka Saxena,Christian Schmidl,Claudio Schneider,Gundula G Schulze-Tanzil,Anita Schwegmann,Guojun Sheng,Jay W Shin,Daisuke Sugiyama,Takaaki Sugiyama,Kim M Summers,Naoko Takahashi,Jun Takai,Hiroshi Tanaka,Hideki Tatsukawa,Andru Tomoiu,Hiroo Toyoda,Marc van de Wetering,Linda M van den Berg,Roberto Verardo,Dipti Vijayan,Christine A Wells,Louise N Winteringham,Ernst Wolvetang,Yoko Yamaguchi,Masayuki Yamamoto,Chiyo Yanagi-Mizuochi,Misako Yoneda,Yohei Yonekura,Peter G Zhang,Silvia Zucchelli,Imad Abugessaisa,Erik Arner,Jayson Harshbarger,Atsushi Kondo,Timo Lassmann,Marina Lizio,Serkan Sahin,Thierry Sengstag,Jessica Severin,Hisashi Shimoji,Masanori Suzuki,Harukazu Suzuki,Jun Kawai,Naoto Kondo,Masayoshi Itoh,Carsten O Daub,Takeya Kasukawa,Hideya Kawaji,Piero Carninci,Alistair R R Forrest,Yoshihide Hayashizaki,Scientific data,Vol. 4,p. 170112-170112,2017年08月29日,研究論文(学術雑誌)
  • A distinct subpopulation of CD25− T-follicular regulatory cells localizes in the germinal centers,James Badger Wing,Yohko Kitagawa,Michela Locci,Hannah Hume,Christopher Tay,Takayoshi Morita,Yujiro Kidani,Kyoko Matsuda,Takeshi Inoue,Tomohiro Kurosaki,Shane Crotty,Cevayir Coban,Naganari Ohkura,Shimon Sakaguchi,Proceedings of the National Academy of Sciences of the United States of America,National Academy of Sciences,Vol. 114,No. 31,p. E6400-E6409,2017年08月01日,研究論文(学術雑誌)
  • Systemic activation of NRF2 alleviates lethal autoimmune inflammation in scurfy mice,Takuma Suzuki,Shohei Murakami,Shyam S. Biswal,Shimon Sakaguchi,Hideo Harigae,Masayuki Yamamoto,Hozumi Motohashi,Molecular and Cellular Biology,American Society for Microbiology,Vol. 37,No. 15,2017年08月01日,研究論文(学術雑誌)
  • Novel interferon-γ enzyme-linked immunoSpot assay using activated cells for identifying hypersensitivity-inducing drug culprits,Kenichi Kato,Asami Kawase,Hiroaki Azukizawa,Takaaki Hanafusa,Yukinobu Nakagawa,Hiroyuki Murota,Shimon Sakaguchi,Hideo Asada,Ichiro Katayama,Journal of Dermatological Science,Elsevier Ireland Ltd,Vol. 86,No. 3,p. 222-229,2017年06月01日,研究論文(学術雑誌)
  • Reciprocal regulation of the Il9 locus by counteracting activities of transcription factors IRF1 and IRF4,Lucia Campos Carrascosa,Matthias Klein,Yohko Kitagawa,Christina Lückel,Federico Marini,Anika König,Anna Guralnik,Hartmann Raifer,Stefanie Hagner-Benes,Diana Rädler,Andreas Böck,Cholho Kang,Michael Lohoff,Holger Garn,Bianca Schaub,Friederike Berberich-Siebelt,Shimon Sakaguchi,Tobias Bopp,Magdalena Huber,Nature Communications,Nature Publishing Group,Vol. 8,2017年05月12日,研究論文(学術雑誌)
  • Essential Roles of SATB1 in Specifying T Lymphocyte Subsets,Kiyokazu Kakugawa,Satoshi Kojo,Hirokazu Tanaka,Wooseok Seo,Takaho A. Endo,Yohko Kitagawa,Sawako Muroi,Mari Tenno,Nighat Yasmin,Yoshinori Kohwi,Shimon Sakaguchi,Terumi Kowhi-Shigematsu,Ichiro Taniuchi,Cell Reports,Elsevier B.V.,Vol. 19,No. 6,p. 1176-1188,2017年05月09日,研究論文(学術雑誌)
  • Unique properties of thymic antigen-presenting cells promote epigenetic imprinting of alloantigen-specific regulatory T cells,Garima Garg,Eirini Nikolouli,Matthias Hardtke-Wolenski,Aras Toker,Naganari Ohkura,Michael Beckstette,Takahisa Miyao,Robert Geffers,Stefan Floess,Norbert Gerdes,Esther Lutgens,Anke Osterloh,Shohei Hori,Shimon Sakaguchi,Elmar Jaeckel,Jochen Huehn,ONCOTARGET,IMPACT JOURNALS LLC,Vol. 8,No. 22,p. 35542-35557,2017年05月,研究論文(学術雑誌)
  • T Regulatory Cells Support Plasma Cell Populations in the Bone Marrow,Arielle Glatman Zaretsky,Christoph Konradt,Fabien Dépis,James B. Wing,Radhika Goenka,Daniela Gomez Atria,Jonathan S. Silver,Sunglim Cho,Amaya I. Wolf,William J. Quinn,Julie B. Engiles,Dorothy C. Brown,Daniel Beiting,Jan Erikson,David Allman,Michael P. Cancro,Shimon Sakaguchi,Li-Fan Lu,Christophe O. Benoist,Christopher A. Hunter,Cell Reports,Elsevier B.V.,Vol. 18,No. 8,p. 1906-1916,2017年02月21日,研究論文(学術雑誌)
  • Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment,Yohko Kitagawa,Naganari Ohkura,Yujiro Kidani,Alexis Vandenbon,Keiji Hirota,Ryoji Kawakami,Keiko Yasuda,Daisuke Motooka,Shota Nakamura,Motonari Kondo,Ichiro Taniuchi,Terumi Kohwi-Shigematsu,Shimon Sakaguchi,Nature Immunology,Nature Publishing Group,Vol. 18,No. 2,p. 173-183,2017年02月01日,研究論文(学術雑誌)
  • ICOS+ Foxp3+ TILs in gastric cancer are prognostic markers and effector regulatory T cells associated with Helicobacter pylori,Hirotsugu Nagase,Tomohira Takeoka,Shinya Urakawa,Akiko Morimoto-Okazawa,Atsunari Kawashima,Kota Iwahori,Shuji Takiguchi,Hiroyoshi Nishikawa,Eiichi Sato,Shimon Sakaguchi,Masaki Mori,Yuichiro Doki,Hisashi Wada,International Journal of Cancer,Wiley-Liss Inc.,Vol. 140,No. 3,p. 686-695,2017年02月01日,研究論文(学術雑誌)
  • Control of Regulatory T Cell Development by the Transcription Factor Foxp3,Shohei Hori,Takashi Nomura,Shimon Sakaguchi,JOURNAL OF IMMUNOLOGY,AMER ASSOC IMMUNOLOGISTS,Vol. 198,No. 3,p. 981-985,2017年02月,研究論文(学術雑誌)
  • Combination of IL-2, rapamycin, DNA methyltransferase and histone deacetylase inhibitors for the expansion of human regulatory T cells,Makoto Miyara,Driss Chader,Aude Burlion,Jérémie Goldstein,Delphine Sterlin,Françoise Norol,Hélène Trebeden-Nègre,Laetitia Claër,Shimon Sakaguchi,Gilles Marodon,Zahir Amoura,Guy Gorochov,Oncotarget,Impact Journals LLC,Vol. 8,No. 62,p. 104733-104744,2017年,研究論文(学術雑誌)
  • UVB exposure prevents atherosclerosis by regulating immunoinflammatory responses,Naoto Sasaki,Tomoya Yamashita,Kazuyuki Kasahara,Atsushi Fukunaga,Tomoyuki Yamaguchi,Takuo Emoto,Keiko Yodoi,Takuya Matsumoto,Kenji Nakajima,Tomoyuki Kita,Masafumi Takeda,Taiji Mizoguchi,Tomohiro Hayashi,Yoshihiro Sasaki,Mayumi Hatakeyama,Kumiko Taguchi,Ken Washio,Shimon Sakaguchi,Bernard Malissen,Chikako Nishigori,Ken-Ichi Hirata,Arteriosclerosis, Thrombosis, and Vascular Biology,Lippincott Williams and Wilkins,Vol. 37,No. 1,p. 66-74,2017年01月01日,研究論文(学術雑誌)
  • Egr2 and Egr3 in regulatory T cells cooperatively control systemic autoimmunity through Ltbp3-mediated TGF-β3 production,Kaoru Morita,Tomohisa Okamura,Mariko Inoue,Toshihiko Komai,Shuzo Teruya,Yukiko Iwasaki,Shuji Sumitomo,Hirofumi Shoda,Kazuhiko Yamamoto,Keishi Fujio,Shimon Sakaguchi,Proceedings of the National Academy of Sciences of the United States of America,National Academy of Sciences,Vol. 113,No. 50,p. E8131-E8140,2016年12月13日,研究論文(国際会議プロシーディングス)
  • Dysbiosis Contributes to Arthritis Development via Activation of Autoreactive T Cells in the Intestine,Yuichi Maeda,Takashi Kurakawa,Eiji Umemoto,Daisuke Motooka,Yoshinaga Ito,Kazuyoshi Gotoh,Keiji Hirota,Masato Matsushita,Yoki Furuta,Masashi Narazaki,Noriko Sakaguchi,Hisako Kayama,Shota Nakamura,Tetsuya Iida,Yukihiko Saeki,Atsushi Kumanogoh,Shimon Sakaguchi,Kiyoshi Takeda,ARTHRITIS & RHEUMATOLOGY,WILEY,Vol. 68,No. 11,p. 2646-2661,2016年11月,研究論文(学術雑誌)
  • The proportion of regulatory T cells in patients with rheumatoid arthritis: A meta-Analysis,Takayoshi Morita,Yoshihito Shima,James Badger Wing,Shimon Sakaguchi,Atsushi Ogata,Atsushi Kumanogoh,PLoS ONE,Public Library of Science,Vol. 11,No. 9,2016年09月01日,研究論文(学術雑誌)
  • Antibody to CMRF35-like molecule 2, CD300e a novel biomarker detected in patients with fulminant type 1 diabetes,Fumitaka Haseda,Akihisa Imagawa,Hiroyoshi Nishikawa,Shinobu Mitsui,Chiharu Tsutsumi,Reiko Fujisawa,Hiroyuki Sano,Yuko Murase-Mishiba,Jungo Terasaki,Shimon Sakaguchi,Toshiaki Hanafusa,PLoS ONE,Public Library of Science,Vol. 11,No. 8,2016年08月01日,研究論文(学術雑誌)
  • Effector Regulatory T Cells Reflect the Equilibrium between Antitumor Immunity and Autoimmunity in Adult T-cell Leukemia,Hiroshi Ureshino,Takero Shindo,Hiroyoshi Nishikawa,Nobukazu Watanabe,Eri Watanabe,Natsuko Satoh,Kazutaka Kitaura,Hiroaki Kitamura,Kazuko Doi,Kotaro Nagase,Hiromi Kimura,Makoto Samukawa,Susumu Kusunoki,Masaharu Miyahara,Tadasu Shin-,Ryuji Suzuki,Shimon Sakaguchi,Shinya Kimura,CANCER IMMUNOLOGY RESEARCH,AMER ASSOC CANCER RESEARCH,Vol. 4,No. 8,p. 644-649,2016年08月,研究論文(学術雑誌)
  • Loss of the Protein Tyrosine Phosphatase PTPN22 Reduces Mannan-Induced Autoimmune Arthritis in SKG Mice,Shatakshi Sood,Rebecca J. Brownlie,Celine Garcia,Graeme Cowan,Robert J. Salmond,Shimon Sakaguchi,Rose Zamoyska,JOURNAL OF IMMUNOLOGY,AMER ASSOC IMMUNOLOGISTS,Vol. 197,No. 2,p. 429-440,2016年07月,研究論文(学術雑誌)
  • Two FOXP3(+)CD4(+) T cell subpopulations distinctly control the prognosis of colorectal cancers.,Takuro Saito,Hiroyoshi Nishikawa,Hisashi Wada,Yuji Nagano,Daisuke Sugiyama,Koji Atarashi,Yuka Maeda,Masahide Hamaguchi,Naganari Ohkura,Eiichi Sato,Hirotsugu Nagase,Junichi Nishimura,Hirofumi Yamamoto,Shuji Takiguchi,Takeshi Tanoue,Wataru Suda,Hidetoshi Morita,Masahira Hattori,Kenya Honda,Masaki Mori,Yuichiro Doki,Shimon Sakaguchi,Nature medicine,Vol. 22,No. 6,p. 679-84,2016年06月,研究論文(学術雑誌)
  • Utility of CD127 combined with FOXP3 for identification of operational tolerance after liver transplantation,Hanaa Nafady-Hego,Ying Li,Hidenori Ohe,Hamed Elgendy,Xiangdong Zhao,Shimon Sakaguchi,G. Alex Bishop,Takaaki Koshiba,Transplant Immunology,Elsevier B.V.,Vol. 36,p. 1-8,2016年05月01日,研究論文(学術雑誌)
  • Development of Regulatory T Cells in the Thymus,Yohko Kitagawa,Shimon Sakaguchi,Encyclopedia of Immunobiology,Elsevier Inc.,Vol. 1,p. 268-274,2016年04月27日,論文集(書籍)内論文
  • Treg Cells,James Badger Wing,Shimon Sakaguchi,Encyclopedia of Immunobiology,Elsevier Inc.,Vol. 3,p. 319-324,2016年04月27日,論文集(書籍)内論文
  • Immuno-Navigator, a batch-corrected coexpression database, reveals cell type-specific gene networks in the immune system,Alexis Vandenbon,Viet H. Dinh,Norihisa Mikami,Yohko Kitagawa,Shunsuke Teraguchi,Naganari Ohkura,Shimon Sakaguchi,Proceedings of the National Academy of Sciences of the United States of America,National Academy of Sciences,Vol. 113,No. 17,p. E2393-2402,2016年04月26日,研究論文(学術雑誌)
  • Induction of autoimmune disease by deletion of CTLA-4 in mice in adulthood,Katrin Klocke,Shimon Sakaguchi,Rikard Holmdahl,Kajsa Wing,PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,NATL ACAD SCIENCES,Vol. 113,No. 17,p. E2383-E2392,2016年04月,研究論文(学術雑誌)
  • Hypomethylation of the Treg-Specific Demethylated Region in FOXP3 Is a Hallmark of the Regulatory T-cell Subtype in Adult T-cell Leukemia,Yayoi Shimazu,Yutaka Shimazu,Masakatsu Hishizawa,Masahide Hamaguchi,Yuya Nagai,Noriko Sugino,Sumie Fujii,Masahiro Kawahara,Norimitsu Kadowaki,Hiroyoshi Nishikawa,Shimon Sakaguchi,Akifumi Takaori-Kondo,CANCER IMMUNOLOGY RESEARCH,AMER ASSOC CANCER RESEARCH,Vol. 4,No. 2,p. 136-145,2016年02月,研究論文(学術雑誌)
  • Capture and release of target cells using a surface that immobilizes an antibody via desthiobiotin-avidin interaction,Tsuyoshi Kimura,Naoko Nakamura,Nao Sasaki,Yoshihide Hashimoto,Shimon Sakaguchi,Shunsaku Kimura,Akio Kishida,Sensors and Materials,M Y U Scientific Publishing Division,Vol. 28,No. 12,p. 1255-1263,2016年,研究論文(学術雑誌)
  • The microbiota regulates type 2 immunity through RORγt<sup>+</sup> T cells,Caspar Ohnmacht,Joo-Hong Park,Sascha Cording,James B. Wing,Koji Atarashi,Yuuki Obata,Valérie Gaboriau-Routhiau,Rute Marques,Sophie Dulauroy,Maria Fedoseeva,Meinrad Busslinger,Nadine Cerf-Bensussan,Ivo G. Boneca,David Voehringer,Koji Hase,Kenya Honda,Shimon Sakaguchi,Gérard Eberl,Science,American Association for the Advancement of Science,Vol. 349,No. 6251,p. 989-993,2015年08月28日,研究論文(学術雑誌)
  • Investigation of the relationship between the onset of arthritis and uveitis in genetically predisposed SKG mice,Ellen J. Lee,Emily E. Vance,Brieanna R. Brown,Paige S. Snow,Jenna S. Clowers,Shimon Sakaguchi,Holly L. Rosenzweig,Arthritis Research and Therapy,BioMed Central Ltd.,Vol. 17,No. 1,2015年08月19日,研究論文(学術雑誌)
  • Sialyl Lewis x (CD15s) identifies highly differentiated and most suppressive FOXP3<sup>high</sup> regulatory T cells in humans,Makoto Miyara,Driss Chader,Edouard Sage,Daisuke Sugiyama,Hiroyoshi Nishikawa,Diane Bouvry,Laetitia Claër,Ravi Hingorani,Robert Balderas,Jurg Rohrer,Noel Warner,Alain Chapelier,Dominique Valeyre,Reiji Kannagi,Shimon Sakaguchi,Zahir Amoura,Guy Gorochov,Proceedings of the National Academy of Sciences of the United States of America,National Academy of Sciences,Vol. 112,No. 23,p. 7225-7230,2015年06月09日,研究論文(学術雑誌)
  • Early life aire: The development of particulart cells at a specific time prevents autoimmunity,Atsushi Tanaka,Shimon Sakaguchi,Science,American Association for the Advancement of Science,Vol. 348,No. 6234,p. 506-507,2015年05月01日,研究論文(学術雑誌)
  • In vivo induction of T-follicular helper cells by modulation of regulatory T cell function,James Badger Wing,Shimon Sakaguchi,T Follicular Helper Cells: Methods and Protocols,Springer New York,p. 77-85,2015年04月02日,論文集(書籍)内論文
  • Transcriptional and Epigenetic Control of Regulatory T Cell Development,Yohko Kitagawa,James Badger Wing,Shimon Sakaguchi,Progress in Molecular Biology and Translational Science,Elsevier B.V.,Vol. 136,p. 1-33,2015年,研究論文(国際会議プロシーディングス)
  • Detection of self-reactive CD8+ T cells with an anergic phenotype in healthy individuals,Yuka Maeda,Hiroyoshi Nishikawa,Daisuke Sugiyama,Danbee Ha,Masahide Hamaguchi,Takuro Saito,Megumi Nishioka,James B. Wing,Dennis Adeegbe,Ichiro Katayama,Shimon Sakaguchi,Science,American Association for the Advancement of Science,Vol. 346,No. 6216,p. 1536-1540,2014年12月19日,研究論文(学術雑誌)
  • Regulatory T cells control antigen-specific expansion of Tfh cell number and humoral immune responses via the coreceptor CTLA-4,James Badger Wing,Wataru Ise,Tomohiro Kurosaki,Shimon Sakaguchi,Immunity,Cell Press,Vol. 41,No. 6,p. 1013-1025,2014年12月18日,研究論文(学術雑誌)
  • Interleukin-10-producing plasmablasts exert regulatory function in autoimmune inflammation,Masanori Matsumoto,Akemi Baba,Takafumi Yokota,Hiroyoshi Nishikawa,Yasuyuki Ohkawa,Hisako Kayama,Axel Kallies,Stephen L. Nutt,Shimon Sakaguchi,Kiyoshi Takeda,Tomohiro Kurosaki,Yoshihiro Baba,Immunity,Cell Press,Vol. 41,No. 6,p. 1040-1051,2014年12月18日,研究論文(学術雑誌)
  • Autosomal dominant immune dysregulation syndrome in humans with CTLA4 mutations,Desireé Schubert,Claudia Bode,Rupert Kenefeck,Tie Zheng Hou,James B. Wing,Alan Kennedy,Alla Bulashevska,Britt-Sabina Petersen,Alejandro A. Schäffer,Björn A. Grüning,Susanne Unger,Natalie Frede,Ulrich Baumann,Torsten Witte,Reinhold E. Schmidt,Gregor Dueckers,Tim Niehues,Suranjith Seneviratne,Maria Kanariou,Carsten Speckmann,Stephan Ehl,Anne Rensing-Ehl,Klaus Warnatz,Mirzokhid Rakhmanov,Robert Thimme,Peter Hasselblatt,Florian Emmerich,Toni Cathomen,Rolf Backofen,Paul Fisch,Maximilian Seidl,Annette May,Annette Schmitt-Graeff,Shinji Ikemizu,Ulrich Salzer,Andre Franke,Shimon Sakaguchi,Lucy S. K. Walker,David M. Sansom,Bodo Grimbacher,Nature Medicine,Nature Publishing Group,Vol. 20,No. 12,p. 1410-1416,2014年12月01日,研究論文(学術雑誌)
  • Continuous T Cell Receptor Signals Maintain a Functional Regulatory T Cell Pool,J. Christoph Vahl,Christoph Drees,Klaus Heger,Sylvia Heink,Julius C. Fischer,Jelena Nedjic,Naganari Ohkura,Hiromasa Morikawa,Hendrik Poeck,Sonja Schallenberg,David Riess,Marco Y. Hein,Thorsten Buch,Bojan Polic,Anne Schoenle,Robert Zeiser,Annette Schmitt-Graeff,Karsten Kretschmer,Ludger Klein,Thomas Korn,Shimon Sakaguchi,Marc Schmidt-Supprian,IMMUNITY,CELL PRESS,Vol. 41,No. 5,p. 722-736,2014年11月,研究論文(学術雑誌)
  • Detection of T cell responses to a ubiquitous cellular protein in autoimmune disease,Yoshinaga Ito,Motomu Hashimoto,Keiji Hirota,Naganari Ohkura,Hiromasa Morikawa,Hiroyoshi Nishikawa,Atsushi Tanaka,Moritoshi Furu,Hiromu Ito,Takao Fujii,Takashi Nomura,Sayuri Yamazaki,Akimichi Morita,Dario A. A. Vignali,John W. Kappler,Shuichi Matsuda,Tsuneyo Mimori,Noriko Sakaguchi,Shimon Sakaguchi,SCIENCE,AMER ASSOC ADVANCEMENT SCIENCE,Vol. 346,No. 6207,p. 363-368,2014年10月,研究論文(学術雑誌)
  • Transient Ablation of Regulatory T cells Improves Antitumor Immunity in Colitis-Associated Colon Cancer,Eva Pastille,Katrin Bardini,Diana Fleissner,Alexandra Adamczyk,Annika Frede,Munisch Wadwa,Dorthe von Smolinski,Stefan Kasper,Tim Sparwasser,Achim D. Gruber,Martin Schuler,Shimon Sakaguchi,Axel Roers,Werner Mueller,Wiebke Hansen,Jan Buer,Astrid M. Westendorf,CANCER RESEARCH,AMER ASSOC CANCER RESEARCH,Vol. 74,No. 16,p. 4258-4269,2014年08月,研究論文(学術雑誌)
  • CD8+tumor-infiltrating lymphocytes at primary sites as a possible prognostic factor of cutaneous angiosarcoma,Hiroko Fujii,Akiko Arakawa,Daisuke Utsumi,Shinji Sumiyoshi,Yosuke Yamamoto,Akihiko Kitoh,Masahiro Ono,Yumi Matsumura,Mayumi Kato,Keisuke Konishi,Takeo Shiga,Shigetoshi Sano,Shimon Sakaguchi,Aya Miyagawa-Hayashino,Kenzo Takahashi,Hiroshi Uezato,Yoshiki Miyachi,Miki Tanioka,International Journal of Cancer,Wiley-Liss Inc.,Vol. 134,No. 10,p. 2393-2402,2014年05月15日,研究論文(学術雑誌)
  • Genetic and epigenetic basis of Treg cell development and function: from a FoxP3-centered view to an epigenome-defined view of natural Treg cells,Hiromasa Morikawa,Shimon Sakaguchi,IMMUNOLOGICAL REVIEWS,WILEY,Vol. 259,No. 1,p. 192-205,2014年05月
  • CD28 signals the differential control of regulatory T cells and effector T cells,Norihisa Mikami,Shimon Sakaguchi,EUROPEAN JOURNAL OF IMMUNOLOGY,WILEY-BLACKWELL,Vol. 44,No. 4,p. 955-957,2014年04月
  • Differential roles of epigenetic changes and Foxp3 expression in regulatory T cell-specific transcriptional regulation,Hiromasa Morikawa,Naganari Ohkura,Alexis Vandenbon,Masayoshi Itoh,Sayaka Nagao-Sato,Hideya Kawaji,Timo Lassmann,Piero Carninci,Yoshihide Hayashizaki,Alistair R. R. Forrest,Daron M. Standley,Hiroshi Date,Shimon Sakaguchi,PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,NATL ACAD SCIENCES,Vol. 111,No. 14,p. 5289-5294,2014年04月,研究論文(学術雑誌)
  • A promoter-level mammalian expression atlas.,Alistair R R Forrest,Hideya Kawaji,Michael Rehli,J Kenneth Baillie,Michiel J L de Hoon,Vanja Haberle,Timo Lassmann,Ivan V Kulakovskiy,Marina Lizio,Masayoshi Itoh,Robin Andersson,Christopher J Mungall,Terrence F Meehan,Sebastian Schmeier,Nicolas Bertin,Mette Jørgensen,Emmanuel Dimont,Erik Arner,Christian Schmidl,Ulf Schaefer,Yulia A Medvedeva,Charles Plessy,Morana Vitezic,Jessica Severin,Colin A Semple,Yuri Ishizu,Robert S Young,Margherita Francescatto,Intikhab Alam,Davide Albanese,Gabriel M Altschuler,Takahiro Arakawa,John A C Archer,Peter Arner,Magda Babina,Sarah Rennie,Piotr J Balwierz,Anthony G Beckhouse,Swati Pradhan-Bhatt,Judith A Blake,Antje Blumenthal,Beatrice Bodega,Alessandro Bonetti,James Briggs,Frank Brombacher,A Maxwell Burroughs,Andrea Califano,Carlo V Cannistraci,Daniel Carbajo,Yun Chen,Marco Chierici,Yari Ciani,Hans C Clevers,Emiliano Dalla,Carrie A Davis,Michael Detmar,Alexander D Diehl,Taeko Dohi,Finn Drabløs,Albert S B Edge,Matthias Edinger,Karl Ekwall,Mitsuhiro Endoh,Hideki Enomoto,Michela Fagiolini,Lynsey Fairbairn,Hai Fang,Mary C Farach-Carson,Geoffrey J Faulkner,Alexander V Favorov,Malcolm E Fisher,Martin C Frith,Rie Fujita,Shiro Fukuda,Cesare Furlanello,Masaaki Furino,Jun-ichi Furusawa,Teunis B Geijtenbeek,Andrew P Gibson,Thomas Gingeras,Daniel Goldowitz,Julian Gough,Sven Guhl,Reto Guler,Stefano Gustincich,Thomas J Ha,Masahide Hamaguchi,Mitsuko Hara,Matthias Harbers,Jayson Harshbarger,Akira Hasegawa,Yuki Hasegawa,Takehiro Hashimoto,Meenhard Herlyn,Kelly J Hitchens,Shannan J Ho Sui,Oliver M Hofmann,Ilka Hoof,Furni Hori,Lukasz Huminiecki,Kei Iida,Tomokatsu Ikawa,Boris R Jankovic,Hui Jia,Anagha Joshi,Giuseppe Jurman,Bogumil Kaczkowski,Chieko Kai,Kaoru Kaida,Ai Kaiho,Kazuhiro Kajiyama,Mutsumi Kanamori-Katayama,Artem S Kasianov,Takeya Kasukawa,Shintaro Katayama,Sachi Kato,Shuji Kawaguchi,Hiroshi Kawamoto,Yuki I Kawamura,Tsugumi Kawashima,Judith S Kempfle,Tony J Kenna,Juha Kere,Levon M Khachigian,Toshio Kitamura,S Peter Klinken,Alan J Knox,Miki Kojima,Soichi Kojima,Naoto Kondo,Haruhiko Koseki,Shigeo Koyasu,Sarah Krampitz,Atsutaka Kubosaki,Andrew T Kwon,Jeroen F J Laros,Weonju Lee,Andreas Lennartsson,Kang Li,Berit Lilje,Leonard Lipovich,Alan Mackay-Sim,Ri-ichiroh Manabe,Jessica C Mar,Benoit Marchand,Anthony Mathelier,Niklas Mejhert,Alison Meynert,Yosuke Mizuno,David A de Lima Morais,Hiromasa Morikawa,Mitsuru Morimoto,Kazuyo Moro,Efthymios Motakis,Hozumi Motohashi,Christine L Mummery,Mitsuyoshi Murata,Sayaka Nagao-Sato,Yutaka Nakachi,Fumio Nakahara,Toshiyuki Nakamura,Yukio Nakamura,Kenichi Nakazato,Erik van Nimwegen,Noriko Ninomiya,Hiromi Nishiyori,Shohei Noma,Shohei Noma,Tadasuke Noazaki,Soichi Ogishima,Naganari Ohkura,Hiroko Ohimiya,Hiroshi Ohno,Mitsuhiro Ohshima,Mariko Okada-Hatakeyama,Yasushi Okazaki,Valerio Orlando,Dmitry A Ovchinnikov,Arnab Pain,Robert Passier,Margaret Patrikakis,Helena Persson,Silvano Piazza,James G D Prendergast,Owen J L Rackham,Jordan A Ramilowski,Mamoon Rashid,Timothy Ravasi,Patrizia Rizzu,Marco Roncador,Sugata Roy,Morten B Rye,Eri Saijyo,Antti Sajantila,Akiko Saka,Shimon Sakaguchi,Mizuho Sakai,Hiroki Sato,Suzana Savvi,Alka Saxena,Claudio Schneider,Erik A Schultes,Gundula G Schulze-Tanzil,Anita Schwegmann,Thierry Sengstag,Guojun Sheng,Hisashi Shimoji,Yishai Shimoni,Jay W Shin,Christophe Simon,Daisuke Sugiyama,Takaai Sugiyama,Masanori Suzuki,Naoko Suzuki,Rolf K Swoboda,Peter A C 't Hoen,Michihira Tagami,Naoko Takahashi,Jun Takai,Hiroshi Tanaka,Hideki Tatsukawa,Zuotian Tatum,Mark Thompson,Hiroo Toyodo,Tetsuro Toyoda,Elvind Valen,Marc van de Wetering,Linda M van den Berg,Roberto Verado,Dipti Vijayan,Ilya E Vorontsov,Wyeth W Wasserman,Shoko Watanabe,Christine A Wells,Louise N Winteringham,Ernst Wolvetang,Emily J Wood,Yoko Yamaguchi,Masayuki Yamamoto,Misako Yoneda,Yohei Yonekura,Shigehiro Yoshida,Susan E Zabierowski,Peter G Zhang,Xiaobei Zhao,Silvia Zucchelli,Kim M Summers,Harukazu Suzuki,Carsten O Daub,Jun Kawai,Peter Heutink,Winston Hide,Tom C Freeman,Boris Lenhard,Vladimir B Bajic,Martin S Taylor,Vsevolod J Makeev,Albin Sandelin,David A Hume,Piero Carninci,Yoshihide Hayashizaki,Nature,Vol. 507,No. 7493,p. 462-70,2014年03月27日,研究論文(学術雑誌)
  • Regulatory T-cell directed therapies in liver diseases,Ye Htun Oo,Shimon Sakaguchi,JOURNAL OF HEPATOLOGY,ELSEVIER SCIENCE BV,Vol. 59,No. 5,p. 1127-1134,2013年11月,研究論文(学術雑誌)
  • Anti-CCR4 mAb selectively depletes effector-Type FoxP3+CD4+ regulatory T cells, evoking antitumor immune responses in humans,Daisuke Sugiyama,Hiroyoshi Nishikawa,Yuka Maeda,Megumi Nishioka,Atsushi Tanemura,Ichiro Katayama,Sachiko Ezoe,Yuzuru Kanakura,Eiichi Sato,Yasuo Fukumori,Julia Karbach,Elke Jäger,Shimon Sakaguchi,Proceedings of the National Academy of Sciences of the United States of America,Vol. 110,No. 44,p. 17945-17950,2013年10月29日,研究論文(学術雑誌)
  • Testosterone Is Protective in the Sexually Dimorphic Development of Arthritis and Lung Disease in SKG Mice,Rebecca C. Keith,Jeremy Sokolove,Benjamin L. Edelman,Lauren Lahey,Elizabeth F. Redente,V. Michael Holers,Shimon Sakaguchi,William H. Robinson,David W. H. Riches,ARTHRITIS AND RHEUMATISM,WILEY-BLACKWELL,Vol. 65,No. 6,p. 1487-1493,2013年06月,研究論文(学術雑誌)
  • Construction of self-recognizing regulatory T cells from conventional T cells by controlling CTLA-4 and IL-2 expression,Tomoyuki Yamaguchi,Ayumi Kishi,Motonao Osaki,Hiromasa Morikawa,Paz Prieto-Martin,Kajsa Wing,Takashi Saito,Shimon Sakaguchi,PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,NATL ACAD SCIENCES,Vol. 110,No. 23,p. E2116-E2125,2013年06月,研究論文(学術雑誌)
  • SKG arthritis as a model for evaluating therapies in rheumatoid arthritis with special focus on bone changes,Kresten Krarup Keller,Lisa Mejlvang Lindgaard,Lise Wogensen,Frederik Dagnæs-Hansen,Jesper Skovhus Thomsen,Shimon Sakaguchi,Kristian Stengaard-Pedersen,Ellen-Margrethe Hauge,Rheumatology International,Vol. 33,No. 5,p. 1127-1133,2013年05月,研究論文(学術雑誌)
  • Overcoming regulatory T-cell suppression by a lyophilized preparation of Streptococcus pyogenes,Michiko Hirayama,Hiroyoshi Nishikawa,Yasuhiro Nagata,Takemasa Tsuji,Takuma Kato,Shinichi Kageyama,Shugo Ueda,Daisuke Sugiyama,Sahoko Hori,Shimon Sakaguchi,Gerd Ritter,Lloyd J. Old,Sacha Gnjatic,Hiroshi Shiku,European Journal of Immunology,Vol. 43,No. 4,p. 989-1000,2013年04月,研究論文(学術雑誌)
  • Identification of novel markers for mouse CD4+ T follicular helper cells,Smita S. Iyer,Donald R. Latner,Michael J. Zilliox,Megan Mccausland,Rama S. Akondy,Pablo Penaloza-Macmaster,Jeffrey Scott Hale,Lilin Ye,Ata-Ur-Rasheed Mohammed,Tomoyuki Yamaguchi,Shimon Sakaguchi,Rama R. Amara,Rafi Ahmed,European Journal of Immunology,Wiley-VCH Verlag,Vol. 43,No. 12,p. 3219-3232,2013年,研究論文(学術雑誌)
  • Expression of CD4(+)CD25(high+) Regulatory T Cells in Miniature Swine,Yan-Ling Wu,Yan-Ping Ding,Chuan-He Wei,Eiji Kobayashi,Shimon Sakaguchi,Takaaki Koshiba,ENVIRONMENTAL PROTECTION AND RESOURCES EXPLOITATION, PTS 1-3,TRANS TECH PUBLICATIONS LTD,Vol. 807-809,p. 708-+,2013年,研究論文(国際会議プロシーディングス)
  • Regulatory T cells,Shimon Sakaguchi,Kajsa Wing,Makoto Miyara,Clinical Immunology: Principles and Practice: Fourth Edition,Elsevier Inc.,p. 193-202,2012年12月12日,論文集(書籍)内論文
  • T Cell Receptor Stimulation-Induced Epigenetic Changes and Foxp3 Expression Are Independent and Complementary Events Required for Treg Cell Development,Naganari Ohkura,Masahide Hamaguchi,Hiromasa Morikawa,Kyoko Sugimura,Atsushi Tanaka,Yoshinaga Ito,Motonao Osaki,Yoshiaki Tanaka,Riu Yamashita,Naoko Nakano,Jochen Huehn,Hans Joerg Fehling,Tim Sparwasser,Kenta Nakai,Shimon Sakaguchi,IMMUNITY,CELL PRESS,Vol. 37,No. 5,p. 785-799,2012年11月,研究論文(学術雑誌)
  • Neuropilin 1 deficiency on CD4(+)Foxp3(+) regulatory T cells impairs mouse melanoma growth,Wiebke Hansen,Marina Hutzler,Simone Abel,Christina Alter,Christian Stockmann,Stefanie Kliche,Juliane Albert,Tim Sparwasser,Shimon Sakaguchi,Astrid M. Westendorf,Dirk Schadendorf,Jan Buer,Iris Helfrich,JOURNAL OF EXPERIMENTAL MEDICINE,ROCKEFELLER UNIV PRESS,Vol. 209,No. 11,p. 2001-2016,2012年10月,研究論文(学術雑誌)
  • Dietary Folic Acid Promotes Survival of Foxp3(+) Regulatory T Cells in the Colon,Makoto Kinoshita,Hisako Kayama,Takashi Kusu,Tomoyuki Yamaguchi,Jun Kunisawa,Hiroshi Kiyono,Shimon Sakaguchi,Kiyoshi Takeda,JOURNAL OF IMMUNOLOGY,AMER ASSOC IMMUNOLOGISTS,Vol. 189,No. 6,p. 2869-2878,2012年09月,研究論文(学術雑誌)
  • Regulatory T cells expressing PPAR-γ control inflammation in obesity,Masahide Hamaguchi,Shimon Sakaguchi,Cell Metabolism,Vol. 16,No. 1,p. 4-6,2012年07月03日,研究論文(学術雑誌)
  • Intracellular Tumor-Associated Antigens Represent Effective Targets for Passive Immunotherapy,Takuro Noguchi,Takuma Kato,Linan Wang,Yuka Maeda,Hiroaki Ikeda,Eiichi Sato,Alexander Knuth,Sacha Gnjatic,Gerd Ritter,Shimon Sakaguchi,Lloyd J. Old,Hiroshi Shiku,Hiroyoshi Nishikawa,CANCER RESEARCH,AMER ASSOC CANCER RESEARCH,Vol. 72,No. 7,p. 1672-1682,2012年04月,研究論文(学術雑誌)
  • Cancer/testis antigens are novel targets of immunotherapy for adult T-cell leukemia/lymphoma,Hiroyoshi Nishikawa,Yuka Maeda,Takashi Ishida,Sacha Gnjatic,Eiichi Sato,Fumiko Mori,Daisuke Sugiyama,Asahi Ito,Yasuo Fukumori,Atae Utsunomiya,Hiroshi Inagaki,Lloyd J. Old,Ryuzo Ueda,Shimon Sakaguchi,Blood,Vol. 119,No. 13,p. 3097-3104,2012年03月29日,研究論文(学術雑誌)
  • Differential effects of inhibition of bone morphogenic protein (BMP) signalling on T-cell activation and differentiation,Yumiko Yoshioka,Masahiro Ono,Motonao Osaki,Ikuo Konishi,Shimon Sakaguchi,European Journal of Immunology,Vol. 42,No. 3,p. 749-759,2012年03月,研究論文(学術雑誌)
  • A novel model of rheumatoid arthritis-associated interstitial lung disease in SKG mice,Rebecca C. Keith,Jennifer L. Powers,Elizabeth F. Redente,Amen Sergew,Richard J. Martin,Alison Gizinski,V. Michael Holers,Shimon Sakaguchi,David W. H. Riches,EXPERIMENTAL LUNG RESEARCH,INFORMA HEALTHCARE,Vol. 38,No. 2,p. 55-66,2012年03月,研究論文(学術雑誌)
  • A trans-ethnic genetic study of rheumatoid arthritis identified FCGR2A as a candidate common risk factor in Japanese and European populations,Roubila Meziani,Ryo Yamada,Meiko Takahashi,Kenei Ohigashi,Akio Morinobu,Chikashi Terao,Hitomi Hiratani,Koichiro Ohmura,Masao Yamaguchi,Takashi Nomura,Alexandre Vasilescu,Miki Kokubo,Victor Renault,Katsura Hirosawa,Chanavee Ratanajaraya,Simon Heath,Tsuneyo Mimori,Shimon Sakaguchi,Mark Lathrop,Inga Melchers,Shunichi Kumagai,Fumihiko Matsuda,Modern Rheumatology,Vol. 22,No. 1,p. 52-58,2012年02月,研究論文(学術雑誌)
  • Treatment of advanced tumors with agonistic anti-GITR mAb and its effects on tumor-infiltrating Foxp3(+)CD25(+)CD4(+) regulatory T cells (vol 202, pg 885, 2005),Kuibeom Ko,Sayuri Yamazaki,Kyoko Nakamura,Tomohisa Nishioka,Keiji Hirota,Tomoyuki Yamaguchi,Jun Shimizu,Takashi Nomura,Tsutomu Chiba,Shimon Sakaguchi,JOURNAL OF EXPERIMENTAL MEDICINE,ROCKEFELLER UNIV PRESS,Vol. 209,No. 2,2012年02月
  • Factors affecting operational tolerance after pediatric living-donor liver transplantation: Impact of early post-transplant events and HLA match,Hidenori Ohe,Kayo Waki,Mami Yoshitomi,Takeshi Morimoto,Hanaa Nafady-Hego,Naoki Satoda,Ying Li,Xiangdong Zhao,Shimon Sakaguchi,Shinji Uemoto,G. Alex Bishop,Takaaki Koshiba,Transplant International,Vol. 25,No. 1,p. 97-106,2012年01月,研究論文(学術雑誌)
  • Re-establishing immunological self-tolerance in autoimmune disease,Shimon Sakaguchi,Fiona Powrie,Richard M. Ransohoff,NATURE MEDICINE,NATURE PUBLISHING GROUP,Vol. 18,No. 1,p. 54-58,2012年01月,研究論文(学術雑誌)
  • Thymus, innate immunity and autoimmune arthritis: Interplay of gene and environment,Shimon Sakaguchi,Satoshi Tanaka,Atsushi Tanaka,Yoshinaga Ito,Shinji Maeda,Noriko Sakaguchi,Motomu Hashimoto,FEBS LETTERS,ELSEVIER SCIENCE BV,Vol. 585,No. 23,p. 3633-3639,2011年12月
  • The Long-Term Survival Potential of Mature T Lymphocytes Is Programmed During Development in the Thymus,Charles Sinclair,Manoj Saini,Ina Schim van der Loeff,Shimon Sakaguchi,Benedict Seddon,SCIENCE SIGNALING,AMER ASSOC ADVANCEMENT SCIENCE,Vol. 4,No. 199,2011年11月,研究論文(学術雑誌)
  • Perturbations of both nonregulatory and regulatory FOXP3+ T cells in patients with malignant melanoma,H. Fujii,A. Arakawa,A. Kitoh,M. Miyara,M. Kato,S. Kore-Eda,S. Sakaguchi,Y. Miyachi,M. Tanioka,M. Ono,British Journal of Dermatology,Vol. 164,No. 5,p. 1052-1060,2011年05月,研究論文(学術雑誌)
  • Immunologic Self-Tolerance Maintained by Activated T Cells Expressing IL-2 Receptor alpha-Chains (CD25) Breakdown of a Single Mechanism of Self-Tolerance Causes Various Autoimmune Diseases,Shimon Sakaguchi,Noriko Sakaguchi,Masanao Asano,Misako Itoh,Masaaki Toda,JOURNAL OF IMMUNOLOGY,AMER ASSOC IMMUNOLOGISTS,Vol. 186,No. 7,p. 1151-1164,2011年04月,研究論文(学術雑誌)
  • Immunologic Self-Tolerance Maintained by Activated T Cells Expressing IL-2 Receptor alpha-Chains (CD25) Breakdown of a Single Mechanism of Self-Tolerance Causes Various Autoimmune Diseases,Shimon Sakaguchi,Noriko Sakaguchi,Masanao Asano,Misako Itoh,Masaaki Toda,JOURNAL OF IMMUNOLOGY,AMER ASSOC IMMUNOLOGISTS,Vol. 186,No. 7,p. 3808-3821,2011年04月,研究論文(学術雑誌)
  • CSF-1-dependent red pulp macrophages regulate CD4 T cell responses.,Daisuke Kurotaki,Shigeyuki Kon,Kyeonghwa Bae,Koyu Ito,Yutaka Matsui,Yosuke Nakayama,Masashi Kanayama,Chiemi Kimura,Yoshinori Narita,Takashi Nishimura,Kazuya Iwabuchi,Matthias Mack,Nico van Rooijen,Shimon Sakaguchi,Toshimitsu Uede,Junko Morimoto,Journal of immunology (Baltimore, Md. : 1950),4,Vol. 186,No. 4,p. 2229-37,2011年02月15日
  • SLAP Deficiency Enhances Number and Function of Regulatory T Cells Preventing Chronic Autoimmune Arthritis in SKG Mice,Lisa K. Peterson,Laura A. Shaw,Anthony Joetham,Shimon Sakaguchi,Erwin W. Gelfand,Leonard L. Dragone,JOURNAL OF IMMUNOLOGY,AMER ASSOC IMMUNOLOGISTS,Vol. 186,No. 4,p. 2273-2281,2011年02月,研究論文(学術雑誌)
  • HTLV-1 bZIP Factor Induces T-Cell Lymphoma and Systemic Inflammation In Vivo,Yorifumi Satou,Jun-ichirou Yasunaga,Tiejun Zhao,Mika Yoshida,Paola Miyazato,Ken Takai,Kei Shimizu,Koichi Ohshima,Patrick L. Green,Naganari Ohkura,Tomoyuki Yamaguchi,Masahiro Ono,Shimon Sakaguchi,Masao Matsuoka,PLOS PATHOGENS,PUBLIC LIBRARY SCIENCE,Vol. 7,No. 2,2011年02月,研究論文(学術雑誌)
  • Stimulation of the Glucocorticoid-Induced TNF Receptor Family-Related Receptor on CD8 T Cells Induces Protective and High-Avidity T Cell Responses to Tumor-Specific Antigens,Anik L. Cote,Peisheng Zhang,Jeremy A. O'Sullivan,Valerie L. Jacobs,Carli R. Clemis,Shimon Sakaguchi,Jose A. Guevara-Patino,Mary Jo Turk,JOURNAL OF IMMUNOLOGY,AMER ASSOC IMMUNOLOGISTS,Vol. 186,No. 1,p. 275-283,2011年01月,研究論文(学術雑誌)
  • IMPAIRED FUNCTION OF REGULATORY T CELLS BY HTLV-1 bZIP FACTOR(HBZ),Paola Miyazato,Yorifumi Satou,Tomoyuki Yamaguchi,Shimon Sakaguchi,Kouichi Ohshima,Masao Matsuoka,International Union of Microbiological Societies 2011 Congress. Sappaoro, Japan. September 11-16, 2011.,2011年
  • CD8 T Cell-Intrinsic GITR Is Required for T Cell Clonal Expansion and Mouse Survival following Severe Influenza Infection,Laura M. Snell,Ann J. McPherson,Gloria H. Y. Lin,Shimon Sakaguchi,Pier Paolo Pandolfi,Carlo Riccardi,Tania H. Watts,JOURNAL OF IMMUNOLOGY,AMER ASSOC IMMUNOLOGISTS,Vol. 185,No. 12,p. 7223-7234,2010年12月,研究論文(学術雑誌)
  • The Generation of Donor-Specific CD4(+)CD25(++)CD45RA(+) Naive Regulatory T Cells in Operationally Tolerant Patients After Pediatric Living-Donor Liver Transplantation,Hanaa Nafady-Hego,Ying Li,Hidenori Ohe,Xiangdong Zhao,Naoki Satoda,Shimon Sakaguchi,Kathryn Wood,Shinji Uemoto,Takaaki Koshiba,TRANSPLANTATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 90,No. 12,p. 1547-1555,2010年12月,研究論文(学術雑誌)
  • Regulatory T cells in tumor immunity,Hiroyoshi Nishikawa,Shimon Sakaguchi,INTERNATIONAL JOURNAL OF CANCER,JOHN WILEY & SONS INC,Vol. 127,No. 4,p. 759-767,2010年08月,研究論文(学術雑誌)
  • Graded Attenuation of TCR Signaling Elicits Distinct Autoimmune Diseases by Altering Thymic T Cell Selection and Regulatory T Cell Function,Satoshi Tanaka,Shinji Maeda,Motomu Hashimoto,Chihiro Fujimori,Yoshinaga Ito,Shin Teradaira,Keiji Hirota,Hiroyuki Yoshitomi,Tomoya Katakai,Akira Shimizu,Takashi Nomura,Noriko Sakaguchi,Shimon Sakaguchi,JOURNAL OF IMMUNOLOGY,AMER ASSOC IMMUNOLOGISTS,Vol. 185,No. 4,p. 2295-2305,2010年08月,研究論文(学術雑誌)
  • Complement drives Th17 cell differentiation and triggers autoimmune arthritis,Motomu Hashimoto,Keiji Hirota,Hiroyuki Yoshitomi,Shinji Maeda,Shin Teradaira,Shuji Akizuki,Paz Prieto-Martin,Takashi Nomura,Noriko Sakaguchi,Joerg Koehl,Birgitta Heyman,Minoru Takahashi,Teizo Fujita,Tsuneyo Mimori,Shimon Sakaguchi,JOURNAL OF EXPERIMENTAL MEDICINE,ROCKEFELLER UNIV PRESS,Vol. 207,No. 6,p. 1135-1143,2010年06月,研究論文(学術雑誌)
  • Two distinct mechanisms of augmented antitumor activity by modulation of immunostimulatory/inhibitory signals,Jun Mitsui,Hiroyoshi Nishikawa,Daisuke Muraoka,Linan Wang,Takuro Noguchi,Eiichi Sato,Satoshi Kondo,James P. Allison,Shimon Sakaguchi,Lloyd J. Old,Takuma Kato,Hiroshi Shiku,Clinical Cancer Research,Vol. 16,No. 10,p. 2781-2791,2010年05月15日,研究論文(学術雑誌)
  • Multiple Antitumor Mechanisms Downstream of Prophylactic Regulatory T-Cell Depletion,Michele W. L. Teng,Jeremy B. Swann,Bianca von Scheidt,Janelle Sharkey,Nadeen Zerafa,Nicole McLaughlin,Tomoyuki Yamaguchi,Shimon Sakaguchi,Phillip K. Darcy,Mark J. Smyth,CANCER RESEARCH,AMER ASSOC CANCER RESEARCH,Vol. 70,No. 7,p. 2665-2674,2010年04月,研究論文(学術雑誌)
  • Regulation of Zap70 expression during thymocyte development enables temporal separation of CD4 and CD8 repertoire selection at different signaling thresholds,Manoj Saini,Charles Sinclair,Daniel Marshall,Mauro Tolaini,Shimon Sakaguchi,Benedict Seddon,Science Signaling,Vol. 3,No. 114,2010年03月23日,研究論文(学術雑誌)
  • Therapeutic Glucocorticoid-Induced TNF Receptor-Mediated Amplification of CD4(+) T Cell Responses Enhances Antiparasitic Immunity,Ashraful Haque,Amanda C. Stanley,Fiona H. Amante,Fabian de Labastida Rivera,YongHong Zhou,Rachel D. Kuns,Vanessa Yardley,Shimon Sakaguchi,Geoffrey R. Hill,Christian R. Engwerda,JOURNAL OF IMMUNOLOGY,AMER ASSOC IMMUNOLOGISTS,Vol. 184,No. 5,p. 2583-2592,2010年03月,研究論文(学術雑誌)
  • Chronic arthritis leads to disturbances in the bone collagen network,Joana Caetano-Lopes,Ana M. Nery,Helena Canhão,Joana Duarte,Rita Cascão,Ana Rodrigues,Inês P. Perpétuo,Saba Abdulghani,Pedro M. Amaral,Shimon Sakaguchi,Yrjö T. Konttinen,Luís Graça,Maria F. Vaz,João E. Fonseca,Arthritis Research and Therapy,Vol. 12,No. 1,2010年01月15日,研究論文(学術雑誌)
  • Indispensable Role of the Runx1-Cbf beta Transcription Complex for In Vivo-Suppressive Function of FoxP3(+) Regulatory T Cells,Akihiko Kitoh,Masahiro Ono,Yoshinori Naoe,Naganari Ohkura,Tomoyuki Yamaguchi,Hiroko Yaguchi,Issay Kitabayashi,Toshihiko Tsukada,Takashi Nomura,Yoshiki Miyachi,Ichiro Taniuchi,Shimon Sakaguchi,IMMUNITY,CELL PRESS,Vol. 31,No. 4,p. 609-620,2009年10月,研究論文(学術雑誌)
  • CD4+CD25-LAG3+ regulatory T cells controlled by the transcription factor Egr-2,Tomohisa Okamura,Keishi Fujio,Mihoko Shibuya,Shuji Sumitomo,Hirofumi Shoda,Shimon Sakaguchi,Kazuhiko Yamamoto,Proceedings of the National Academy of Sciences of the United States of America,Vol. 106,No. 33,p. 13974-13979,2009年08月18日,研究論文(学術雑誌)
  • Enhancement of T-cell-mediated anti-tumour immunity via the ectopically expressed glucocorticoid-induced tumour necrosis factor receptor-related receptor ligand (GITRL) on tumours,Jinhua Piao,Yosuke Kamimura,Hideyuki Iwai,Yujia Cao,Keisuke Kikuchi,Masaaki Hashiguchi,Taro Masunaga,Hongsi Jiang,Kouichi Tamura,Shimon Sakaguchi,Miyuki Azuma,IMMUNOLOGY,WILEY-BLACKWELL PUBLISHING, INC,Vol. 127,No. 4,p. 489-499,2009年08月,研究論文(学術雑誌)
  • γδ Cells Are the Predominant Source of IL-17 in the Affected Joints of Collagen-Induced Arthritis, but Not in Rheumatoid Arthritis.,Yoshinaga Ito,Takashi Usui,Shio Kobayashi,Mikiko Iguchi-Hashimoto,Hiromu Ito,Hiroyuki Yoshitomi,Takashi Nakamura,Motomu Hashimoto,Noriko Sakaguchi,Shimon Sakaguchi,Hajime Yoshifuji,Takaki Nojima,Koichiro Ohmura,Takao Fujii,Tsuneyo Mimori,Arthritis and Rheumatism,Vol. 60,No. 8,p. 2294-303,2009年08月,研究論文(学術雑誌)
  • Therapeutic Immunity by Adoptive Tumor-primed CD4(+) T-cell Transfer in Combination With In Vivo GITR Ligation,Zuqiang Liu,Shenghe Tian,Louis D. Falo,Shimon Sakaguchi,Zhaoyang You,MOLECULAR THERAPY,NATURE PUBLISHING GROUP,Vol. 17,No. 7,p. 1274-1281,2009年07月,研究論文(学術雑誌)
  • Functional Delineation and Differentiation Dynamics of Human CD4(+) T Cells Expressing the FoxP3 Transcription Factor,Makoto Miyara,Yumiko Yoshioka,Akihiko Kitoh,Tomoko Shima,Kajsa Wing,Akira Niwa,Christophe Parizot,Cecile Taflin,Toshio Heike,Dominique Valeyre,Alexis Mathian,Tatsutoshi Nakahata,Tomoyuki Yamaguchi,Takashi Nomura,Masahiro Ono,Zahir Amoura,Guy Gorochov,Shimon Sakaguchi,IMMUNITY,CELL PRESS,Vol. 30,No. 6,p. 899-911,2009年06月,研究論文(学術雑誌)
  • Therapeutic approaches to allergy and autoimmunity based on FoxP3(+) regulatory T-cell activation and expansion,Makoto Miyara,Kajsa Wing,Shimon Sakaguchi,JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY,MOSBY-ELSEVIER,Vol. 123,No. 4,p. 749-755,2009年04月,研究論文(学術雑誌)
  • Immune Rejection of Mouse Tumors Expressing Mutated Self,Fei Duan,Yun Lin,Cailian Liu,Manuel E. Engelhorn,Adam D. Cohen,Michael Curran,Shimon Sakaguchi,Taha Merghoub,Stephanie Terzulli,Jedd D. Wolchok,Alan N. Houghton,CANCER RESEARCH,AMER ASSOC CANCER RESEARCH,Vol. 69,No. 8,p. 3545-3553,2009年04月,研究論文(学術雑誌)
  • Differential control of allo-antigen-specific regulatory T cells and effector T cells by anti-CD4 and other agents in establishing transplantation tolerance,Kanji Nagahama,Zoltan Fehervari,Takatoku Oida,Tomoyuki Yamaguchi,Osamu Ogawa,Shimon Sakaguchi,INTERNATIONAL IMMUNOLOGY,OXFORD UNIV PRESS,Vol. 21,No. 4,p. 379-391,2009年04月,研究論文(学術雑誌)
  • [Contribution of Th-1, Th-2, Th-17 or regulatory T cells to connective tissue diseases].,Motomu Hashimoto,Shimon Sakaguchi,Nihon rinsho. Japanese journal of clinical medicine,Vol. 67,No. 3,p. 482-6,2009年03月,研究論文(学術雑誌)
  • A simple detection method for low-affinity membrane protein interactions by baculoviral display,Toshiko Sakihama,Takato Sato,Hiroko Iwanari,Toshio Kitamura,Shimon Sakaguchi,Tatsuhiko Kodama,Takao Hamakubo,PLoS ONE,Vol. 3,No. 12,2008年12月24日,研究論文(学術雑誌)
  • Value of FOXP3 Expression in Peripheral Blood as Rejection Marker After Miniature Swine Lung Transplantation,Naoki Satoda,Tsuyoshi Shoji,Yanling Wu,Takuji Fujinaga,Fengshi Chen,Akihiro Aoyama,Ji Tian Zhang,Ayuko Takahashi,Toshihiro Okamoto,Izumi Matsumoto,Hiroaki Sakai,Ying Li,Xiangdong Zhao,Toshiaki Manabe,Eiji Kobayashi,Shimon Sakaguchi,Hiromi Wada,Hidenori Ohe,Shinji Uemoto,Junichi Tottori,Toru Bando,Hiroshi Date,Takaaki Koshiba,Journal of Heart and Lung Transplantation,Vol. 27,No. 12,p. 1293-1301,2008年12月,研究論文(学術雑誌)
  • The Presence of Foxp3 Expressing T Cells Within Grafts of Tolerant Human Liver Transplant Recipients,Ying Li,Xiangdong Zhao,Donghua Cheng,Hironori Haga,Tatsuaki Tsuruyama,Kathryn Wood,Shimon Sakaguchi,Koichi Tanaka,Shinji Uemoto,Takaaki Koshiba,TRANSPLANTATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 86,No. 12,p. 1837-1843,2008年12月,研究論文(学術雑誌)
  • CTLA-4 control over Foxp3(+) regulatory T cell function,Kajsa Wing,Yasushi Onishi,Paz Prieto-Martin,Tomoyuki Yamaguchi,Makoto Miyara,Zoltan Fehervari,Takashi Nomura,Shimon Sakaguchi,SCIENCE,AMER ASSOC ADVANCEMENT SCIENCE,Vol. 322,No. 5899,p. 271-275,2008年10月,研究論文(学術雑誌)
  • Arthritis and pneumonitis produced by the same T cell clones from mice with spontaneous autoimmune arthritis,Chiaki Wakasa-Morimoto,Tomoko Toyosaki-Maeda,Takaji Matsutani,Ryu Yoshida,Shino Nakamura-Kikuoka,Miki Maeda-Tanimura,Hiroyuki Yoshitomi,Keiji Hirota,Motomu Hashimoto,Hideyuki Masaki,Yoshiki Fujii,Tsuneaki Sakata,Yuji Tsuruta,Ryuji Suzuki,Noriko Sakaguchi,Shimon Sakaguchi,INTERNATIONAL IMMUNOLOGY,OXFORD UNIV PRESS,Vol. 20,No. 10,p. 1331-1342,2008年10月,研究論文(学術雑誌)
  • Systemic targeting of CpG-ODN to the tumor microenvironment with anti-neu-CpG hybrid molecule and T regulatory cell depletion induces memory responses in BALB-neuT tolerant mice,Sanjay Sharma,Ana Lucia Dominguez,Soraya Zorro Manrique,Federica Cavallo,Shimon Sakaguchi,Joseph Lustgarten,CANCER RESEARCH,AMER ASSOC CANCER RESEARCH,Vol. 68,No. 18,p. 7530-7540,2008年09月,研究論文(学術雑誌)
  • Foxp3(+) natural regulatory T cells preferentially form aggregates on dendritic cells in vitro and actively inhibit their maturation,Yasushi Onishi,Zoltan Fehervari,Tomoyuki Yamaguchi,Shimon Sakaguchi,PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,NATL ACAD SCIENCES,Vol. 105,No. 29,p. 10113-10118,2008年07月,研究論文(学術雑誌)
  • Regulatory T cells and immune tolerance,Shimon Sakaguchi,Tomoyuki Yamaguchi,Takashi Nomura,Masahiro Ono,CELL,CELL PRESS,Vol. 133,No. 5,p. 775-787,2008年05月
  • Regulatory T cells in the past and for the future,Shimon Sakaguchi,European Journal of Immunology,Vol. 38,No. 4,p. 901-903,2008年04月,研究論文(学術雑誌)
  • Regulatory t cells,Kajsa Wing,Shimon Sakaguchi,Clinical Immunology,Elsevier Ltd,p. 249-258,2008年,論文集(書籍)内論文
  • Functional delineation and differentiation dynamics \nof FoxP3-expressing subpopulation of CD4+ T cell in humans,Makoto Miyara,Tomoko Shima,Akihiko Kitoh,Yumiko Yosioka,Akira Niwa,Cecile Taflin,Toshio Heike,DominiqueValeyre,Alexis Mathian,Zahir Amoura,Tatsutoshi Nakahata,Tomoyuki Yamaguchi,Takashi Nomura,Kajsa Wing,Guy Gorochov,Masahiro Ono,Shimon Sakaguchi,World Immune Regulation Meeting-II (2008.3.17-20 Davos Switzerland),2008年
  • γδT 細胞はコラーゲン誘発性関 \n節炎局所における主要なIl-17 産生細胞である/Ganmma delta T cells are the predominant Il-17-produsing cells \nin affected joint of collagen-induced arthritis,Yoshinaga Ito,Takashi Usui,Shio Kobayashi,Mikiko Iguchi,Hiromu Ito,Hiroyoki Yoshitomi,Takashi Nakamura,Motomu Hashimoto,Noriko Sakaguchi,Shimon Sakaguchi,Tuneyo Mimori,第8回日本免疫学会学術集会(2008.12.1-3.京都),2008年
  • Regulatory T cells - A brief history and perspective,Shimon Sakaguchi,Kajsa Wing,Makoto Miyara,European Journal of Immunology,Vol. 37,No. 1,p. S116-S123,2007年11月,研究論文(学術雑誌)
  • Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model,Keiji Hirota,Hiroyuki Yoshitomi,Motomu Hashimoto,Shinji Maeda,Shin Teradaira,Naoshi Sugimoto,Tomoyuki Yamaguchi,Takashi Nomura,Hiromu Ito,Takashi Nakamura,Noriko Sakaguchi,Shimon Sakaguchi,JOURNAL OF EXPERIMENTAL MEDICINE,ROCKEFELLER UNIV PRESS,Vol. 204,No. 12,p. 2803-2812,2007年11月,研究論文(学術雑誌)
  • A combination of chemoimmunotherapies can efficiently break self-tolerance and induce antitumor immunity in a tolerogenic murine tumor model,Hyun-Jeong Ko,Yeon-Jeong Kim,Yun-Sun Kim,Woo-Sung Chang,Sung-Youl Ko,Sun-Young Chang,Shimon Sakaguchi,Chang-Yuil Kang,CANCER RESEARCH,AMER ASSOC CANCER RESEARCH,Vol. 67,No. 15,p. 7477-7486,2007年08月,研究論文(学術雑誌)
  • Control of immune responses by antigen-specific regulatory T cells expressing the folate receptor,Tomoyuki Yamaguchi,Keiji Hirota,Kanji Nagahama,Katsuya Ohkawa,Takeshi Takahashi,Takeshi Nomura,Shimon Sakaguchi,IMMUNITY,CELL PRESS,Vol. 27,No. 1,p. 145-159,2007年07月,研究論文(学術雑誌)
  • Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1,Masahiro Ono,Hiroko Yaguchi,Naganari Ohkura,Issay Kitabayashi,Yuko Nagamura,Takashi Nomura,Yoshiki Miyachi,Toshihiko Tsukada,Shimon Sakaguchi,Nature,Nature Publishing Group,Vol. 446,No. 7136,p. 685-689,2007年04月05日,研究論文(学術雑誌)
  • ICER/CREM-mediated transcriptional attenuation of IL-2 and its role in suppression by regulatory T cells,Josef Bodor,Zoltan Fehervari,Betty Diamond,Shimon Sakaguchi,European Journal of Immunology,Vol. 37,No. 4,p. 884-895,2007年04月,研究論文(学術雑誌)
  • Clinical, immunological, and pathological aspects of operational tolerance after pediatric living-donor liver transplantation,Takaaki Koshiba,Ying Li,Mami Takemura,Yanling Wu,Shimon Sakaguchi,Nagahiro Minato,Kathryn J. Wood,Hironori Haga,Mikiko Ueda,Shinji Uemoto,TRANSPLANT IMMUNOLOGY,ELSEVIER SCIENCE BV,Vol. 17,No. 2,p. 94-97,2007年02月,研究論文(学術雑誌)
  • Regulatory T cell-mediated suppression: potential role of ICER,Josef Bodor,Zoltan Fehervari,Betty Diamond,Shimon Sakaguchi,JOURNAL OF LEUKOCYTE BIOLOGY,FEDERATION AMER SOC EXP BIOL,Vol. 81,No. 1,p. 161-167,2007年01月,研究論文(学術雑誌)
  • T cell self-reactivity forms a cytokine milieu for spontaneous development of IL-17(+) Th cells that cause autoimmune arthritis,Keiji Hirota,Motomu Hashimoto,Hiroyuki Yoshitomi,Satoshi Tanaka,Takashi Nomura,Tomoyuki Yamaguchi,Yoichiro Iwakura,Noriko Sakaguchi,Shimon Sakaguchi,JOURNAL OF EXPERIMENTAL MEDICINE,ROCKEFELLER UNIV PRESS,Vol. 204,No. 1,p. 41-47,2007年01月,研究論文(学術雑誌)
  • GITRL/GITR のCD4+T 細胞機能への作用TNF ファミリーの分子リウマチ学-基礎から臨 床へ―,清水淳,坂口志文,分子リウマチVol.4 No.4 2007(46-51),2007年
  • Spontaneous large-scale lymphoid neogenesis and balanced autoimmunity versus tolerance in the stomach of H+/K+-ATPase-Reactive TCR transgenic mouse,Tomoya Katakai,Takashi Nomura,Hiroyuki Gonda,Manabu Sugai,Yasutoshi Agata,Akiyoshi Nishio,Tohru Masuda,Shimon Sakaguchi,Akira Shimizu,JOURNAL OF IMMUNOLOGY,AMER ASSOC IMMUNOLOGISTS,Vol. 177,No. 11,p. 7858-7867,2006年12月,研究論文(学術雑誌)
  • Glucocorticoid-induced tumour necrosis factor receptor family-related receptor signalling exacerbates hapten-induced colitis by CD4(+) T cells,Sun K. Lee,Beom K. Choi,Young H. Kim,Woo J. Kang,Kwang H. Kim,Shimon Sakaguchi,Jae H. Suh,Tae Y. Kim,Byoung S. Kwon,IMMUNOLOGY,BLACKWELL PUBLISHING,Vol. 119,No. 4,p. 479-487,2006年12月,研究論文(学術雑誌)
  • A role for Dicer in immune regulation,Bradley S. Cobb,Arnulf Hertweck,James Smith,Eric O'Connor,Daniel Graf,Terence Cook,Stephen T. Smale,Shimon Sakaguchi,Frederick J. Livesey,Amanda G. Fisher,Matthias Merkenschlager,Journal of Experimental Medicine,Vol. 203,No. 11,p. 2519-2527,2006年10月,研究論文(学術雑誌)
  • Cytokine production profile of splenocytes derived from zymosan A-treated SKG mice developing arthritis,K. Kobayashi,T. Suda,K. Nan-ya,N. Sakaguchi,S. Sakaguchi,I. Miki,Inflammation Research,Vol. 55,No. 8,p. 335-341,2006年08月,研究論文(学術雑誌)
  • Foxp3(+)CD25(+)CD4(+) natural regulatory T cells in dominant self-tolerance and autoimmune disease,Shimon Sakaguchi,Masahiro Ono,Ruka Setoguchi,Haruhiko Yagi,Shohei Hori,Zoltan Fehervari,Jun Shimizu,Takeshi Takahashi,Takashi Nomura,IMMUNOLOGICAL REVIEWS,BLACKWELL PUBLISHING,Vol. 212,p. 8-27,2006年08月
  • Foxp3-dependent and -independent molecules specific for CD25(+)CD4(+) natural regulatory T cells revealed by DNA microarray analysis,Naoshi Sugimoto,Takatoku Oida,Keiji Hirota,Kyoko Nakamura,Takashi Nomura,Takashi Uchiyama,Shimon Sakaguchi,INTERNATIONAL IMMUNOLOGY,OXFORD UNIV PRESS,Vol. 18,No. 8,p. 1197-1209,2006年08月,研究論文(学術雑誌)
  • Delineation of immunoregulatory properties of adult T-cell leukemia cells,Yasushi Matsubara,Toshiyuki Hori,Rimpei Morita,Shimon Sakaguchi,Takashi Uchiyama,International Journal of Hematology,Vol. 84,No. 1,p. 63-69,2006年07月,研究論文(学術雑誌)
  • Glucocorticoid-induced TNF receptor family related gene activation overcomes tolerance/ignorance to melanoma differentiation antigens and enhances antitumor immunity,Teresa Ramirez-Montagut,Andrew Chow,Daniel Hirschhorn-Cymerman,Theis H. Terwey,Adam A. Kochman,Sydney Lu,Randy C. Miles,Shimon Sakaguchi,Alan N. Houghton,Marcel R. M. Van Den Brink,Journal of Immunology,American Association of Immunologists,Vol. 176,No. 11,p. 6434-6442,2006年06月01日,研究論文(学術雑誌)
  • CD4+CD25+Foxp3+ T cells and CD4 +CD25-Foxp3+ T cells in aged mice,Tomohisa Nishioka,Jun Shimizu,Ryuji Iida,Sayuri Yamazaki,Shimon Sakaguchi,Journal of Immunology,American Association of Immunologists,Vol. 176,No. 11,p. 6586-6593,2006年06月01日,研究論文(学術雑誌)
  • Agonist anti-GITR antibody enhances vaccine-induced CD8+ T-cell responses and tumor immunity,Adam D. Cohen,Adi Diab,Miguel-Angel Perales,Jedd D. Wolchok,Gabrielle Rizzuto,Taha Merghoub,Deonka Huggins,Cailian Liu,Mary Jo Turk,Nicholas P. Restifo,Shimon Sakaguchi,Alan N. Houghton,Cancer Research,Vol. 66,No. 9,p. 4904-4912,2006年05月01日,研究論文(学術雑誌)
  • Conversion of alloantigen-specific CD8(+) T cell anergy to CD8(+) T cell priming through in vivo ligation of glucocorticoid-induced TNF receptor,Juyang Kim,Woon S. Choi,Hyun Kang,Hye J. Kim,Jae-Hee Suh,Shimon Sakaguchi,Byungsuk Kwon,JOURNAL OF IMMUNOLOGY,AMER ASSOC IMMUNOLOGISTS,Vol. 176,No. 9,p. 5223-5231,2006年05月,研究論文(学術雑誌)
  • Control of autoimmune myocarditis and multiorgan inflammation by glucocorticoid-induced TNF receptor family-related protein high, Foxp3-expressing CD25(+) and CD25(-) regulatory T cells,M Ono,J Shimizu,Y Miyachi,S Sakaguchi,JOURNAL OF IMMUNOLOGY,AMER ASSOC IMMUNOLOGISTS,Vol. 176,No. 8,p. 4748-4756,2006年04月,研究論文(学術雑誌)
  • Autoimmunity,Jean-François Bach,Shimon Sakaguchi,Current Opinion in Immunology,Vol. 17,No. 6,p. 567-569,2005年12月,研究論文(学術雑誌)
  • Treatment of advanced tumors with agonistic anti-GITR mAb and its effects on tumor-infiltrating Foxp3+CD25+CD4+ regulatory T cells,Kuibeom Ko,Sayuri Yamazaki,Kyoko Nakamura,Tomohisa Nishioka,Keiji Hirota,Tomoyuki Yamaguchi,Jun Shimizu,Takashi Nomura,Tsutomu Chiba,Shimon Sakaguchi,Journal of Experimental Medicine,Vol. 202,No. 7,p. 885-891,2005年10月03日,研究論文(学術雑誌)
  • Analysis of the underlying cellular mechanisms of anti-CD154-induced graft tolerance: The interplay of clonal anergy and immune regulation,Sergio A. Quezada,Kathy Bennett,Bruce R. Blazar,Alexander Y. Rudensky,Shimon Sakaguchi,Randolph J. Noelle,Journal of Immunology,American Association of Immunologists,Vol. 175,No. 2,p. 771-779,2005年07月15日,研究論文(学術雑誌)
  • Regulatory T cells, derived from naïve CD4+CD25- T cells by in vitro Foxp3 gene transfer, can induce transplantation tolerance,Jian-Guo Chai,Shao-An Xue,David Coe,Caroline Addey,Istvan Bartok,Diane Scott,Elizabeth Simpson,Hans J. Stauss,Shohei Hori,Shimon Sakaguchi,Julian Dyson,Transplantation,Vol. 79,No. 10,p. 1310-1316,2005年05月27日,研究論文(学術雑誌)
  • Regulatory T cells in autoimmune diseases: Preface,Shimon Sakaguchi,International Reviews of Immunology,Vol. 24,No. 3-4,p. 157-158,2005年05月,研究論文(学術雑誌)
  • A role for fungal β-glucans and their receptor Dectin-1 in the induction of autoimmune arthritis in genetically susceptible mice,Hiroyuki Yoshitomi,Noriko Sakaguchi,Katsuya Kobayashi,Gordon D. Brown,Tomoyuki Tagami,Toshiko Sakihama,Keiji Hirota,Satoshi Tanaka,Takashi Nomura,Ichiro Miki,Siamon Gordon,Shizuo Akira,Takashi Nakamura,Shimon Sakaguchi,Journal of Experimental Medicine,Vol. 201,No. 6,p. 949-960,2005年03月21日,研究論文(学術雑誌)
  • Definition of target antigens for naturally occurring CD4+ CD25+ regulatory T cells,Hiroyoshi Nishikawa,Takuma Kato,Isao Tawara,Kanako Saito,Hiroaki Ikeda,Kagemasa Kuribayashi,Paul M. Allen,Robert D. Schreiber,Shimon Sakaguchi,Lloyd J. Old,Hiroshi Shiku,Journal of Experimental Medicine,Vol. 201,No. 5,p. 681-686,2005年03月07日,研究論文(学術雑誌)
  • Homeostatic maintenance of natural Foxp3+ CD25+ CD4+ regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization,Ruka Setoguchi,Shohei Hori,Takeshi Takahashi,Shimon Sakaguchi,Journal of Experimental Medicine,Vol. 201,No. 5,p. 723-735,2005年03月07日,研究論文(学術雑誌)
  • Cutting edge: Contact-mediated suppression by CD4+CD25 + regulatory cells involves a granzyme B-dependent, perforin-independent mechanism,David C. Gondek,Li-Fan Lu,Sergio A. Quezada,Shimon Sakaguchi,Randolph J. Noelle,Journal of Immunology,American Association of Immunologists,Vol. 174,No. 4,p. 1783-1786,2005年02月15日,研究論文(学術雑誌)
  • Regulatory T: Cells,Zoltán Fehérvari,Shimon Sakaguchi,Measuring Immunity: Basic Biology and Clinical Assessment,Elsevier Ltd,p. 322-335,2005年,論文集(書籍)内論文
  • Regulatory T cell and autoimmune diseases,Satoshi Tanaka,Shimon Sakaguchi,Japanese Journal of Clinical Immunology,Vol. 28,No. 5,p. 291-299,2005年,研究論文(学術雑誌)
  • 内在性制御性T 細胞と自己免疫疾患医学のあゆみ,瀬戸口留可,坂口志文,2005 Vol. 213 No. 1(69-73),2005年
  • IL - 2 and autoimmunity : homeostatic maintenance of CD25+4+ regulatory T cells via IL - 2 secreted by other T cells and induction of autoimmune desease by IL - 2 neutralization.,Ruka Setoguchi,Shohei Hori,Takeshi Takahashi,Shimon Sakaguchi,Keystone Symposia Cellular Senescence and Cell Death(2005 3. 3-8. Colorado,USA),2005年
  • Generation of autoaggresive CD4+ T cells due to a ZAP-70 point mutation in SKG mice that spontaneous develop autoimmune arthritis.,Keiji Hirota,Hiroyuki Yoshitomi,Satoshi Tanaka,Takashi Nomura,Noriko Sakaguchi,Shimon Sakaguchi,Keystone Symposia Cellular Senescence and Cell Death(2005 3. 3-8. Colorado, USA),2005年
  • Control of Foxp3+ CD25+CD4+ regulatory cell activation and function by dendritic cells,Zoltán Fehérvári,Shimon Sakaguchi,International Immunology,Vol. 16,No. 12,p. 1769-1780,2004年12月,研究論文(学術雑誌)
  • Analyses of peripheral blood mononuclear cells in operational tolerance after pediatric living donor liver transplantation,Ying Li,Takaaki Koshiba,Atsushi Yoshizawa,Yukihide Yonekawa,Kosuke Masuda,Atsushi Ito,Mikiko Ueda,Takahide Mori,Hiroshi Kawamoto,Yoshimasa Tanaka,Shimon Sakaguchi,Nagahiro Minato,Kathryn J. Wood,Koichi Tanaka,American Journal of Transplantation,Vol. 4,No. 12,p. 2118-2125,2004年12月,研究論文(学術雑誌)
  • Reduction of retrovirus-induced immunosuppression by in vivo modulation of T cells during acute infection,Hong He,Ronald J. Messer,Shimon Sakaguchi,Guojun Yang,Shelly J. Robertson,Kim J. Hasenkrug,Journal of Virology,Vol. 78,No. 21,p. 11641-11647,2004年11月,研究論文(学術雑誌)
  • Induction of antigen-specific immunologic tolerance by in vivo and in vitro antigen-specific expansion of naturally arising Foxp3+ CD25+ CD4+ regulatory T cells,Eiji Nishimura,Toshiko Sakihama,Ruka Setoguchi,Koichi Tanaka,Shimon Sakaguchi,International Immunology,Vol. 16,No. 8,p. 1189-1201,2004年08月,研究論文(学術雑誌)
  • Distinct contribution of IL-6, TNF-α, IL-1, and IL-10 to T cell-mediated spontaneous autoimmune arthritis in mice,Hiroshi Hata,Noriko Sakaguchi,Hiroyuki Yoshitomi,Yoichiroh Iwakura,Kenji Sekikawa,Yoshiaki Azuma,Chieko Kanai,Eiko Moriizumi,Takashi Nomura,Takashi Nakamura,Shimon Sakaguchi,Journal of Clinical Investigation,Vol. 114,No. 4,p. 582-588,2004年08月,研究論文(学術雑誌)
  • GITR activation induces an opposite effect on alloreactive CD4+ and CD8+ T cells in graft-versus-host disease,Stephanie J. Muriglan,Teresa Ramirez-Montagut,Onder Alpdogan,Thomas W. Van Huystee,Jeffrey M. Eng,Vanessa M. Hubbard,Adam A. Kochman,Kartono H. Tjoe,Carlo Riccardi,Pier Paolo Pandolfi,Shimon Sakaguchi,Alan N. Houghton,Marcel R.M. Van Den Brink,Journal of Experimental Medicine,Vol. 200,No. 2,p. 149-157,2004年07月19日,研究論文(学術雑誌)
  • CD25+CD4+ T cells in human cord blood: An immunoregulatory subset with naive phenotype and specific expression of forkhead box p3 (Foxp3) gene,Yasushi Takahata,Akihiko Nomura,Hidetoshi Takada,Shouichi Ohga,Kenji Furuno,Shunji Hikino,Hideki Nakayama,Shimon Sakaguchi,Toshiro Hara,Experimental Hematology,Vol. 32,No. 7,p. 622-629,2004年07月,研究論文(学術雑誌)
  • Costimulation via glucocorticoid-induced TNF receptor in both conventional and CD25+ regulatory CD4+ T cells,Fumiko Kanamaru,Pornpan Youngnak,Masaaki Hashiguchi,Tomohisa Nishioka,Takeshi Takahashi,Shimon Sakaguchi,Isao Ishikawa,Miyuki Azuma,Journal of Immunology,American Association of Immunologists,Vol. 172,No. 12,p. 7306-7314,2004年06月15日,研究論文(学術雑誌)
  • 4-1BB-dependent inhibition of immunosuppression by activated CD4 +CD25+ T cells,Beom K. Choi,Jun S. Bae,Eun M. Choi,Woo J. Kang,Shimon Sakaguchi,Dass S. Vinay,Byoung S. Kwon,Journal of Leukocyte Biology,Vol. 75,No. 5,p. 785-791,2004年05月,研究論文(国際会議プロシーディングス)
  • Functional impairment of CD8+ T cells by regulatory T cells during persistent retroviral infection,Ulf Dittmer,Hong He,Ronald J. Messer,Simone Schimmer,Anke R.M. Olbrich,Claes Ohlen,Philip D. Greenberg,Ingunn M. Stromnes,Michihiro Iwashiro,Shimon Sakaguchi,Leonard H. Evans,Karin E. Peterson,Guojun Yang,Kim J. Hasenkrug,Immunity,Vol. 20,No. 3,p. 293-303,2004年03月,研究論文(学術雑誌)
  • NF-κB-Inducing Kinase Establishes Self-Tolerance in A Thymic Stroma-Dependent Manner,Fumiko Kajiura,Shijie Sun,Takashi Nomura,Keisuke Izumi,Tomoo Ueno,Yoshimi Bando,Noriyuki Kuroda,Hongwei Han,Yi Li,Akemi Matsushima,Yousuke Takahama,Shimon Sakaguchi,Tasuku Mitani,Mitsuru Matsumoto,Journal of Immunology,Vol. 172,No. 4,p. 2067-2075,2004年02月15日,研究論文(学術雑誌)
  • Regulation of autoimmune diabetes by non-islet-specific T cells - A role for the glucocorticoid-induced TNF receptor,Anish Suri,Jun Shimizu,Jonathan D. Katz,Shimon Sakaguchi,Emil R. Unanue,Osami Kanagawa,European Journal of Immunology,Vol. 34,No. 2,p. 447-454,2004年02月,研究論文(学術雑誌)
  • IL-10 is involved in the suppression of experimental autoimmune encephalomyelitis by CD25+CD4+ regulatory T cells,Xingmin Zhang,Djordje N. Koldzic,Leonid Izikson,Jayagopala Reddy,Remedios F. Nazareno,Shimon Sakaguchi,Vijay K. Kuchroo,Howard L. Weiner,International Immunology,Vol. 16,No. 2,p. 249-256,2004年02月,研究論文(学術雑誌)
  • Altered thymic T-cell selection due to a spontaneous mutation of the ZAP-70 gene causes autoimmune arthritis,N Sakaguchi,T Takahashi,H Hata,T Nomura,T Tagami,S Yamazaki,T Sakihama,Negishi, I,S Nakatsuru,S Sakaguchi,IMMUNOLOGY 2004: AUTOIMMUNITY, GENETIC AND DEGENERATIVE DISORDERS, MALIGNANCIES, AND TRANSPLANTATION,MEDIMOND PUBLISHING CO,p. 239-242,2004年,研究論文(国際会議プロシーディングス)
  • Induction of fatal autoimmune myocarditis and other autoimmune diseases in mice by depleting Foxp3-expressing T cells,M Ono,J Shimizu,Y Miyachi,S Sakaguchi,IMMUNOLOGY 2004: AUTOIMMUNITY, GENETIC AND DEGENERATIVE DISORDERS, MALIGNANCIES, AND TRANSPLANTATION,MEDIMOND PUBLISHING CO,p. 193-195,2004年,研究論文(国際会議プロシーディングス)
  • Crucial role of FOXP3 in the development of human CD25+4+ regulatory T cells.,Haruhiko Yagi,Takashi Nomura,Kyoko Nakamura,Toshio Kitawaki,Masafumi Onodera,Takashi Uchiyama,Shingo Fujii,Shimon Sakaguchi,Keystone Symposia Regulatory/Suppressor T Cells(2004.3.10-15. Banff Canada),2004年
  • Tumor Immunotherapy with anti GITR monoclonal antibody in mice.,Keiji Hirota,Kwibeom Ko,Sayuri Yamazaki,Jun Shimizu,Kyoko Nakamura,Tomoyuki Yamaguchi,Takashi Nomura,Shimon Sakaguchi,Keystone Symposia Regulatory/Suppressor T Cells(2004.3.10-15. Banff Canada),2004年
  • Neutralization of IL-2 breaks immunological self-tolerance by reducing the \nnumber of CD25+4+regulatory T cells.,Ruka Setoguchi,Shimon Sakaguchi,Keystone Symposia Regulatory/Suppressor T Cells(2004.3.10-15. Banff Canada),2004年
  • Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice,Noriko Sakaguchi,Takeshi Takahashi,Hiroshi Hata,Takashi Nomura,Tomoyuki Tagami,Sayuri Yamazaki,Toshiko Sakihama,Takaji Matsutani,Izumi Negishi,Syuichi Nakatsuru,Shimon Sakaguchi,Nature,Vol. 426,No. 6965,p. 454-460,2003年11月27日,研究論文(学術雑誌)
  • Control of regulatory T cell development by the transcription factor Foxp3,Shohei Hori,Takashi Nomura,Shimon Sakaguchi,Science,Vol. 299,No. 5609,p. 1057-1061,2003年02月14日,研究論文(学術雑誌)
  • Regulatory T cells: Mediating compromises between host and parasite,Shimon Sakaguchi,Nature Immunology,Vol. 4,No. 1,p. 10-11,2003年01月01日,研究論文(学術雑誌)
  • Stimulation of CD25+CD4+ regulatory T cells through GITR breaks immunological self-tolerance,Jun Shimizu,Sayuri Yamazaki,Takeshi Takahashi,Yasumasa Ishida,Shimon Sakaguchi,Nature Immunology,Vol. 3,No. 2,p. 135-142,2002年,研究論文(学術雑誌)
  • Increased T cell autoreactivity in the absence of CD40-CD40 ligand interactions: A role of CD40 in regulatory T cell development,A. Kumanogoh,X. Wang,I. Lee,C. Watanabe,M. Kamanaka,W. Shi,K. Yoshida,T. Sato,S. Habu,M. Itoh,N. Sakaguchi,S. Sakaguchi,H. Kikutani,Journal of Immunology,American Association of Immunologists,Vol. 166,No. 1,p. 353-360,2001年01月01日,研究論文(学術雑誌)
  • Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: Their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance,Shimon Sakaguchi,Noriko Sakaguchi,Jun Shimizu,Sayuri Yamazaki,Toshiko Sakihama,Misako Itoh,Yuhshi Kuniyasu,Takashi Nomura,Masaaki Toda,Takeshi Takahashi,Immunological Reviews,Vol. 182,p. 18-32,2001年
  • Immunologic self tolerance maintained by T-cell-mediated control of self-reactive T cells: Implications for autoimmunity and tumor immunity,Shimon Sakaguchi,Takeshi Takahashi,Sayuri Yamazaki,Yuhshi Kuniyasu,Misako Itoh,Noriko Sakaguchi,Jun Shimizu,Microbes and Infection,Elsevier Masson SAS,Vol. 3,No. 11,p. 911-918,2001年
  • Breaking Immunologic Tolerance to Tumor Cells As a Novel Immunotherapy for Cancer,Shimon Sakaguchi,Jun Shimizu,Keio Journal of Medicine,Vol. 48,p. A7-A12,1999年,研究論文(学術雑誌)
  • IMMUNOLOGICAL PROPERTIES OF FC RECEPTOR ON LYMPHOCYTES .10. ANTIGEN-SPECIFIC FCR-GAMMA-T AND ANTIGEN-NONSPECIFIC FCR-GAMMA+T SUPPRESSORS IN IMMUNE TOLERANCE,K USAMI,M MIYAMAINABA,K KURIBAYASHI,S SAKAGUCHI,M HANAOKA,T MASUDA,ACTA HAEMATOLOGICA JAPONICA,JAPAN HEMATOL SOC,Vol. 45,No. 4,p. 772-784,1982年,研究論文(学術雑誌)

MISC

  • Ultraviolet B-induced maturation of CD11b-Type Langerin<sup>2</sup> dendritic cells controls the expansion of foxp3<sup>+</sup> regulatory t cells in the skin,Sayuri Yamazaki,Mizuyu Odanaka,Akiko Nishioka,Saori Kasuya,Hiroaki Shime,Hiroaki Hemmi,Masaki Imai,Dieter Riethmacher,Tsuneyasu Kaisho,Naganari Ohkura,Shimon Sakaguchi,Akimichi Morita,Journal of Immunology,Vol. 200,No. 1,p. 119-129,2018年01月01日
  • Molecular control of regulatory T cell development and function,Yohko Kitagawa,Shimon Sakaguchi,Current Opinion in Immunology,Elsevier Ltd,Vol. 49,p. 64-70,2017年12月01日,書評論文,書評,文献紹介等
  • Regulatory T cells in cancer immunotherapy,Atsushi Tanaka,Shimon Sakaguchi,Cell Research,Nature Publishing Group,Vol. 27,No. 1,p. 109-118,2017年01月01日,書評論文,書評,文献紹介等
  • The innate immune receptor NOD2 is protective against autoimmune-induced arthritis in SKG mice,Ruth J. Napier,Emily Vance,Paige Snow,Ellen J. Lee,Shimon Sakaguchi,Holly L. Rosenzweig,JOURNAL OF IMMUNOLOGY,AMER ASSOC IMMUNOLOGISTS,Vol. 196,2016年05月,研究発表ペーパー・要旨(国際会議)
  • 関節リウマチの病態形成に関与するT細胞クローンの同定と新規自己抗原RPL23A,廣田圭司,橋本求,坂口志文,感染・炎症・免疫,Vol. 45,No. 3,p. 240‐243-70,2015年10月15日
  • Comment on "Cutting Edge: Epigenetic Regulation of Foxp3 Defines a Stable Population of CD4(+) Regulatory T Cells in Tumors from Mice and Humans",Jochen Huehn,Stefan Floess,Naganari Ohkura,Shimon Sakaguchi,JOURNAL OF IMMUNOLOGY,AMER ASSOC IMMUNOLOGISTS,Vol. 194,No. 8,p. 33533-33533,2015年04月,速報,短報,研究ノート等(学術雑誌)
  • Epigenetic control of thymic Treg-cell development,Yohko Kitagawa,Naganari Ohkura,Shimon Sakaguchi,European Journal of Immunology,Wiley-VCH Verlag,Vol. 45,No. 1,p. 11-16,2015年01月01日,書評論文,書評,文献紹介等
  • Homeostasis of thymus-derived Foxp3<sup>+</sup> regulatory T cells is controlled by ultraviolet B exposure in the skin,Sayuri Yamazaki,Akiko Nishioka,Saori Kasuya,Naganari Ohkura,Hiroaki Hemmi,Tsuneyasu Kaisho,Osamu Taguchi,Shimon Sakaguchi,Akimichi Morita,Journal of Immunology,AMER ASSOC IMMUNOLOGISTS,Vol. 193,No. 11,p. 5488-5497,2014年12月01日
  • T-REG-cell therapies for autoimmune rheumatic diseases,Makoto Miyara,Yoshinaga Ito,Shimon Sakaguchi,NATURE REVIEWS RHEUMATOLOGY,NATURE PUBLISHING GROUP,Vol. 10,No. 9,p. 543-551,2014年09月,書評論文,書評,文献紹介等
  • Regulatory T cells in cancer immunotherapy,Hiroyoshi Nishikawa,Shimon Sakaguchi,Current Opinion in Immunology,Vol. 27,No. 1,p. 1-7,2014年04月,書評論文,書評,文献紹介等
  • Foxp3 T-reg cells in humoral immunity,James B. Wing,Shimon Sakaguchi,INTERNATIONAL IMMUNOLOGY,OXFORD UNIV PRESS,Vol. 26,No. 2,p. 61-69,2014年02月,書評論文,書評,文献紹介等
  • Comprehensive exploration of autoantibody in Behçet's disease: A novel autoantibody to claudin-1, an essential protein for tight junctions, is identified,Atsuyoshi Morishima,Toru Hirano,Hiroyoshi Nishikawa,Kei Nakai,Shimon Sakaguchi,Atsushi Kumanogoh,Joint Bone Spine,Elsevier Masson SAS,Vol. 81,No. 6,p. 546-548,2014年,速報,短報,研究ノート等(学術雑誌)
  • The plasticity and stability of regulatory T cells,Shimon Sakaguchi,Dario A. A. Vignali,Alexander Y. Rudensky,Rachel E. Niec,Herman Waldmann,Nature Reviews Immunology,Vol. 13,No. 6,p. 461-467,2013年06月,書評論文,書評,文献紹介等
  • Regulatory T cells: Recommendations to simplify the nomenclature,Abul K. Abbas,Christophe Benoist,Jeffrey A. Bluestone,Daniel J. Campbell,Sankar Ghosh,Shohei Hori,Shuiping Jiang,Vijay K. Kuchroo,Diane Mathis,Maria Grazia Roncarolo,Alexander Rudensky,Shimon Sakaguchi,Ethan M. Shevach,Dario A. A. Vignali,Steve F. Ziegler,Nature Immunology,Vol. 14,No. 4,p. 307-308,2013年04月,速報,短報,研究ノート等(学術雑誌)
  • Development and Maintenance of Regulatory T cells,Naganari Ohkura,Yohko Kitagawa,Shimon Sakaguchi,Immunity,Vol. 38,No. 3,p. 414-423,2013年03月21日,書評論文,書評,文献紹介等
  • Molecular determinants of regulatory T cell development: The essential roles of epigenetic changes,Yohko Kitagawa,Naganari Ohkura,Shimon Sakaguchi,Frontiers in Immunology,Vol. 4,No. MAY,2013年,書評論文,書評,文献紹介等
  • Treg Cells Acquire New Directions, Cytokines Navigate,Naganari Ohkura,Shimon Sakaguchi,Immunity,Vol. 37,No. 3,p. 443-444,2012年09月21日,書評論文,書評,文献紹介等
  • Re-establishing immunological self-tolerance in autoimmune disease (vol 18, pg 54, 2012),Shimon Sakaguchi,Fiona Powrie,Richard M. Ransohoff,NATURE MEDICINE,NATURE PUBLISHING GROUP,Vol. 18,No. 4,p. 630-630,2012年04月
  • T-cell receptor signaling and the pathogenesis of autoimmune arthritis: insights from mouse and man,Shimon Sakaguchi,Helen Benham,Andrew P. Cope,Ranjeny Thomas,IMMUNOLOGY AND CELL BIOLOGY,NATURE PUBLISHING GROUP,Vol. 90,No. 3,p. 277-287,2012年03月,書評論文,書評,文献紹介等
  • Multiple Treg suppressive modules and their adaptability,James B. Wing,Shimon Sakaguchi,Frontiers in Immunology,Vol. 3,2012年,書評論文,書評,文献紹介等
  • Autoimmune arthritis caused by altered thymic T-cell selection due to a mutation of the ZAP-70 gene,Yoshinaga Ito,Shimon Sakaguchi,ARTHRITIS RESEARCH & THERAPY,BIOMED CENTRAL LTD,Vol. 14,2012年,研究発表ペーパー・要旨(国際会議)
  • The contribution and cellular source of GM-CSF in a murine model of autoimmunity,Nicholas Edward Crabb,Motomu Hashimoto,Yoshinaga Ito,Tosei Murase,Atushi Tanaka,Shimon Sakaguchi,Kyoto T Cell Conference 第22 回学術集会(2012.7.6-7.京都),2012年
  • Concurrent epigenetic conversion and Foxp3 expression have \ncomplementary roles in the development of regulatory T cells,Masahide Hamaguchi,Naganari Ohkura,Hiromasa Morikawa,Kyoko Sugimura,Atsushi Tanaka,Yoshinaga Ito,Motonao Osaki,Yoshiaki Tanaka,Riu Yamashita,Naoko Nakano,Jochen Huehn,Tim Sparwasser,Kenta Nakai,Shimon Sakaguchi,Joint Symposium of Seoul St. Mary’s Hop, Osaka Univ. Postech.(2011. 12. 19. Seoul, Korea),2011年12月19日
  • Two modes of immune suppression by Foxp3+ regulatory T cells under inflammatory or non-inflammatory conditions,Tomoyuki Yamaguchi,James B. Wing,Shimon Sakaguchi,Seminars in Immunology,Vol. 23,No. 6,p. 424-430,2011年12月,書評論文,書評,文献紹介等
  • TCR diversity and Treg cells, sometimes more is more,James B. Wing,Shimon Sakaguchi,European Journal of Immunology,Vol. 41,No. 11,p. 3097-3100,2011年11月,速報,短報,研究ノート等(学術雑誌)
  • Human FoxP3(+) regulatory T cells in systemic autoimmune diseases,Makoto Miyara,Guy Gorochov,Michael Ehrenstein,Lucile Musset,Shimon Sakaguchi,Zahir Amoura,AUTOIMMUNITY REVIEWS,ELSEVIER SCIENCE BV,Vol. 10,No. 12,p. 744-755,2011年10月,書評論文,書評,文献紹介等
  • Cell-autonomous and -non-autonomous roles of CTLA-4 in immune regulation,Kajsa Wing,Tomoyuki Yamaguchi,Shimon Sakaguchi,Trends in Immunology,Vol. 32,No. 9,p. 428-433,2011年09月,書評論文,書評,文献紹介等
  • SIGNIFICANCE OF CD127 VERSUS FOXP3 TO DEFINE REGULATORY T CELLS IN TOLERANT RECIPIENTS AFTER PEDIATRIC LIVING-DONOR LIVER TRANSPLANTATION,Hanaa Nafady-Hego,Ying Li,Hidenori Ohe,Hamed Elgendy,Shimon Sakaguchi,Shinji Uemoto,Takaaki Koshiba,TRANSPLANT INTERNATIONAL,WILEY-BLACKWELL,Vol. 24,p. 225-225,2011年09月,研究発表ペーパー・要旨(国際会議)
  • Damping by depletion,Shimon Sakaguchi,Kajsa Wing,Science,Vol. 332,No. 6029,p. 542-543,2011年04月29日,書評論文,書評,文献紹介等
  • Minimal but essential doses of immunosuppression: A more realistic approach to improve long-term outcomes for pediatric living-donor liver transplantation,Hidenori Ohe,Ying Li,Hanaa Nafady-Hego,Waki Kayo,Shimon Sakaguchi,Kathryn Wood,Roy Calne,Shinji Uemoto,Takaaki Koshiba,Transplantation,Vol. 91,No. 7,p. 809-810,2011年04月15日,速報,短報,研究ノート等(学術雑誌)
  • Maturation of effector regulatory T cells,Naganari Ohkura,Shimon Sakaguchi,NATURE IMMUNOLOGY,NATURE PUBLISHING GROUP,Vol. 12,No. 4,p. 283-284,2011年04月
  • Human FoxP3+ CD4+ regulatory T cells: Their knowns and unknowns,Makoto Miyara,Shimon Sakaguchi,Immunology and Cell Biology,Vol. 89,No. 3,p. 346-351,2011年03月,書評論文,書評,文献紹介等
  • FOXP3 + regulatory T cells: Control of FOXP3 expression by pharmacological agents,Naganari Ohkura,Masahide Hamaguchi,Shimon Sakaguchi,Trends in Pharmacological Sciences,Vol. 32,No. 3,p. 158-166,2011年03月,書評論文,書評,文献紹介等
  • THE ROLE OF GITR IN CD8 T CELL RESPONSES TO INFLUENZA VIRUS,Laura M. Snell,Gloria H. Y. Lin,Carlo Riccardi,Pier P. Pandolfi,Shimon Sakaguchi,Tania H. Watts,ADVANCES IN TNF FAMILY RESEARCH,SPRINGER-VERLAG BERLIN,Vol. 691,p. 767-767,2011年,研究発表ペーパー・要旨(国際会議)
  • Foxo1 and Foxo3 help Foxp3,Naganari Ohkura,Shimon Sakaguchi,Immunity,Vol. 33,No. 6,p. 835-837,2010年12月14日,書評論文,書評,文献紹介等
  • IMMUNOLOGY Conditional stability of T cells,Shimon Sakaguchi,NATURE,NATURE PUBLISHING GROUP,Vol. 468,No. 7320,p. 41-42,2010年11月
  • BMPシグナリングはT細胞の分化とサイトカイン産生を調節する,吉岡弓子,小野昌弘,大崎一直,濱西潤三,馬場長,松村謙臣,万代昌紀,坂口志文,小西郁生,日本癌学会第69回学術集会,2010年10月
  • FOXP3(+) regulatory T cells in the human immune system,Shimon Sakaguchi,Makoto Miyara,Cristina M. Costantino,David A. Hafler,NATURE REVIEWS IMMUNOLOGY,NATURE PUBLISHING GROUP,Vol. 10,No. 7,p. 490-500,2010年07月,書評論文,書評,文献紹介等
  • Regulatory T cells: roles of T cell receptor for their development and function,Naganari Ohkura,Shimon Sakaguchi,SEMINARS IN IMMUNOPATHOLOGY,SPRINGER HEIDELBERG,Vol. 32,No. 2,p. 95-106,2010年06月,書評論文,書評,文献紹介等
  • CD8 T cells require intrinsic GITR signaling for their clonal expansion during influenza infection in vivo,Laura Snell,Ann McPherson,Gloria Lin,Shimon Sakaguchi,Pier Pandolfi,Carlo Riccardi,Tania Watts,JOURNAL OF IMMUNOLOGY,AMER ASSOC IMMUNOLOGISTS,Vol. 184,2010年04月,研究発表ペーパー・要旨(国際会議)
  • Adoptive Transfer of Ex Vivo Donor Alloantigen-Stimulated Regulatory T Cells Combined with Low Dose Tacrolimus Ameliorates Rejection of Lung Transplantation between Fully Mismatched Miniature Swines.,Naoki Satoda,Ying Li,Shimon Sakaguchi,Hiroshi Date,Shinji Uemoto,Takaaki Koshiba,AMERICAN JOURNAL OF TRANSPLANTATION,WILEY-BLACKWELL PUBLISHING, INC,Vol. 10,p. 140-140,2010年04月,研究発表ペーパー・要旨(国際会議)
  • Regulatory T cells exert checks and balances on self tolerance and autoimmunity,Kajsa Wing,Shimon Sakaguchi,NATURE IMMUNOLOGY,NATURE PUBLISHING GROUP,Vol. 11,No. 1,p. 7-13,2010年01月,書評論文,書評,文献紹介等
  • Constitutive Expression of IDO by Dendritic Cells of Mesenteric Lymph Nodes: Functional Involvement of the CTLA-4/B7 and CCL22/CCR4 Interactions,Toshiharu Onodera,Myoung Ho Jang,Zijin Guo,Mikako Yamasaki,Takako Hirata,Zhongbin Bai,Noriko M. Tsuji,Daisuke Nagakubo,Osamu Yoshie,Shimon Sakaguchi,Osamu Takikawa,Masayuki Miyasaka,JOURNAL OF IMMUNOLOGY,AMER ASSOC IMMUNOLOGISTS,Vol. 183,No. 9,p. 5608-5614,2009年11月
  • Regulatory T cells: how do they suppress immune responses?,Shimon Sakaguchi,Kajsa Wing,Yasushi Onishi,Paz Prieto-Martin,Tomoyuki Yamaguchi,INTERNATIONAL IMMUNOLOGY,OXFORD UNIV PRESS,Vol. 21,No. 10,p. 1105-1111,2009年10月,書評論文,書評,文献紹介等
  • Dynamics of peripheral tolerance and immune regulation mediated by Treg,Shimon Sakaguchi,Kajsa Wing,Tomoyuki Yamaguchi,European Journal of Immunology,Vol. 39,No. 9,p. 2331-2336,2009年09月,書評論文,書評,文献紹介等
  • ADOPTIVE TRANSFER OF EX VIVO DONOR ALLOANTIGEN-STIMULATED CD4(+)CD25(++) REGULATORY T CELLS AMELIORATES REJECTION OF LUNG TRANSPLANTATION BETWEEN FULLY MISMATCHED MINIATURE SWINES,Naoki Satoda,Ying Li,Tsuyoshi Shoji,Xiangdong Zhao,Hiroyuki Kanazawa,Hidenori Ohe,Toru Bando,Junichi Tottori,Shimon Sakaguchi,Eiji Kobayashi,Shinji Uemoto,Hiromi Wada,Hiroshi Date,Takaaki Koshiba,TRANSPLANT INTERNATIONAL,WILEY-BLACKWELL,Vol. 22,p. 30-30,2009年08月,研究発表ペーパー・要旨(国際会議)
  • CRITICAL ROLE OF NEWLY IDENTIFIED CD4(+)CD25(++)CD45RA(+) NAIVE REGULATORY T CELLS IN OPERATIONAL TOLERANCE AFTER PEDIATRIC LIVING-DONOR LIVER TRANSPLANTATION,Hanaa Abdelhakeem Nafady-Hego,Ying Li,Shimon Sakaguchi,Kathryn Wood,Shinji Uemoto,Takaaki Koshiba,TRANSPLANT INTERNATIONAL,WILEY-BLACKWELL,Vol. 22,p. 30-30,2009年08月,研究発表ペーパー・要旨(国際会議)
  • A novel modifier of regulatory T cells,Naganari Ohkura,Shimon Sakaguchi,NATURE IMMUNOLOGY,NATURE PUBLISHING GROUP,Vol. 10,No. 7,p. 685-686,2009年07月
  • Pregnancy-Induced Rheumatoid Arthritis Amelioration in SKG Mice,Leonard Dragone,Laura A. Shaw,Kristen K. Rumer,Anita Kramer,Shimon Sakaguchi,Virginia D. Winn,JOURNAL OF IMMUNOLOGY,AMER ASSOC IMMUNOLOGISTS,Vol. 182,2009年04月,研究発表ペーパー・要旨(国際会議)
  • Pregnancy-Induced Rheumatoid Arthritis (RA) Amelioration in SKG Mice,Virginia D. Winn,Laura Shaw,Kristen K. Rumer,Anita Kramer,Shimon Sakaguchi,Leonard L. Dragone,REPRODUCTIVE SCIENCES,SAGE PUBLICATIONS INC,Vol. 16,No. 3,p. 83A-83A,2009年03月,研究発表ペーパー・要旨(国際会議)
  • Adoptive Transfer of Ex Vivo Donor Alloantigen-Stimulated CD4(+)CD25(+)FoxP3(+) Regulatory T Cells Ameliorates Rejection of Lung Transplantation between Fully Mismatched Miniature Swines.,Tsuyoshi Shoji,Ying Li,Naoki Satoda,Hidenori Ohe,Hiroyuki Kanazawa,Toru Bando,Shinji Uemoto,Eiji Kobayashi,Hiromi Wada,Shimon Sakaguchi,Hiroshi Date,Takaaki Koshiba,AMERICAN JOURNAL OF TRANSPLANTATION,WILEY-BLACKWELL,Vol. 9,p. 382-382,2009年,研究発表ペーパー・要旨(国際会議)
  • Regulatory T cells for self-tolerance and immune homeostasis,Shimon Sakaguchi,ARCHIVES OF DERMATOLOGICAL RESEARCH,SPRINGER,Vol. 301,No. 1,p. 34-34,2009年01月,研究発表ペーパー・要旨(国際会議)
  • Control of T cell differentiation and cytokine production by an axis made \nby a set of morphogens,吉岡弓子,小野昌弘,小西郁生,坂口志文,第39回日本免疫学会総会学術集会 (2009.12.2-4 大阪),2009年
  • 正常ZAP-70 の発現量操作による自己免疫性関節炎の誘導,前田伸治,田中聡,廣田圭司,藤森千尋,野村尚史,秋月修治,橋本求,伊藤能永,坂口教子,坂口志文,第39回日本免疫学会総会学術集会(2009.12.2-4大阪),2009年
  • 補体によるTh-17 依存性自己免疫性関節炎の制御,橋本求,廣田圭司,吉冨啓之,前田伸治,寺平晋,秋月修治,Prieto-Martin Paz,野村尚史,坂口教子,高橋 実,藤田貞三,三森経世,坂口志文,第39 回日本免疫学会総会学術集会(2009.12.2-4 大阪),2009年
  • 関節リウマチ 動物モデル SKGマウスの関節炎発症におけるdectin-1依存的、非依存的な経路の解析,橋本 求,廣田 圭司,吉冨 啓之,前田 伸治,寺平 晋,野村 尚史,坂口 教子,岩倉 洋一郎,三森 経世,坂口 志文,日本免疫学会総会・学術集会記録,(NPO)日本免疫学会,Vol. 38,p. 172-172,2008年11月
  • Recruitment of FOXP3 expressing regulatory T cells into tolerant graft of human liver transplantation,Ying Li,Xiangdong Zhao,Hironori Haga,Tatsuaki Tdsuruyama,Kathryn J. Wood,Shimon Sakaguchi,Shinji Uemoto,Takaaki Koshiba,AMERICAN JOURNAL OF TRANSPLANTATION,BLACKWELL PUBLISHING,Vol. 8,p. 290-291,2008年05月,研究発表ペーパー・要旨(国際会議)
  • 「免疫難病・感染症等の先進医療技術」「制御性T細胞による新しい免疫制御法の開発」TCRシグナル伝達の補正によるSKGマウス自己免疫性関節炎の発症抑制,前田伸治,田中聡,廣田圭司,橋本求,寺平晋,秋月修治,野村尚史,上田龍三,坂口教子,坂口志文,免疫難病・感染症等の先進医療技術 第5回(最終)公開シンポジウム要旨集 平成20年,2008年
  • TCR シグナル伝達の補正によるSKG マウス自己免疫性関節炎の発症抑制/Rescue of autoimmune arthritis in SKG mice by normalization of TCR signal transduction,前田伸治,田中聡,廣田圭司,橋本求,寺平晋,秋月修治,野村尚史,上田龍三,坂口教子,坂口志文,第38回日本免疫学会学術集会(2008.12.1-3.京都),2008年
  • SKG マウスの関節炎発症におけるdectine-1 依存的,非依存的な経路の解析/Dectin-1-dependant and - independent pathway for the induction of arthritis in SKG mice,橋本求,廣田圭司,吉冨啓之,前田伸治,寺平晋,野村尚史,坂口教子,岩倉洋一郎,三森経世,坂口志文,第38回日本免疫学会学術集会(2008.12.1-3. 京都),2008年
  • 免疫疾患と制御 4.Th17とSKG関節炎,廣田圭司,坂口志文,Annual Review 免疫,Vol. 2008,p. 273-279,2007年11月20日
  • GITR Ligation and CD4(+) T-cell combination therapy eradicates an aggressive solid tumor by concomitantly enhancing antitumor immunity while inhibiting treg suppressive activity,Zuqiang Liu,Hae S. Noh,Louis D. Falo,Shimon Sakaguchi,Zhaoyang You,JOURNAL OF IMMUNOTHERAPY,LIPPINCOTT WILLIAMS & WILKINS,Vol. 30,No. 8,p. 873-874,2007年11月,研究発表ペーパー・要旨(国際会議)
  • TCRシグナル伝達の補正によるSKGマウス自己免疫性関節炎の発症抑制,前田 伸治,田中 聡,廣田 圭司,寺平 晋,橋本 求,野村 尚史,上田 龍三,坂口 教子,坂口 志文,日本免疫学会総会・学術集会記録,(NPO)日本免疫学会,Vol. 37,p. 135-135,2007年10月
  • Emerging challenges in regulatory T cell function and biology,Shimon Sakaguchi,Fiona Powrie,Science,Vol. 317,No. 5838,p. 627-629,2007年08月03日,書評論文,書評,文献紹介等
  • GITRL-mediated costimulation in CD25(-) conventional and CD25(+) regulatory CD4 T cells,Hanna Igarashi,Jinhua Piao,Yujia Cao,Masaaki Hashiguchi,Hideyuki Iwai,Teruo Amagasa,Shimon Sakaguchi,Miyuki Azuma,JOURNAL OF IMMUNOLOGY,AMER ASSOC IMMUNOLOGISTS,Vol. 178,2007年04月,研究発表ペーパー・要旨(国際会議)
  • Involvement of GITRL-GITR costimulatory pathway in T cell-mediated immune responses in vivo,Jinhua Piao,Kamimura Yosuke,Igarashi Hanna,Hideyuki Iwai,Hashiguchi Massaaki,Sakaguchi Shimon,Miyuki Azuma,JOURNAL OF IMMUNOLOGY,AMER ASSOC IMMUNOLOGISTS,Vol. 178,2007年04月,研究発表ペーパー・要旨(国際会議)
  • Foxp3 and Aire in thymus-generated T-reg cells: a link in self-tolerance,Takashi Nomura,Shimon Sakaguchi,NATURE IMMUNOLOGY,NATURE PUBLISHING GROUP,Vol. 8,No. 4,p. 333-334,2007年04月
  • Natural regulatory T cells: mechanisms of suppression,Makoto Miyara,Shimon Sakaguchi,TRENDS IN MOLECULAR MEDICINE,ELSEVIER SCI LTD,Vol. 13,No. 3,p. 108-116,2007年03月,書評論文,書評,文献紹介等
  • Regulatory T cells as potential immunotherapy in allergy,Kajsa Wing,Shimon Sakaguchi,CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY,LIPPINCOTT WILLIAMS & WILKINS,Vol. 6,No. 6,p. 482-488,2006年12月,書評論文,書評,文献紹介等
  • Skin controls immune regulators,Tomoyuki Yamaguchi,Shimon Sakaguchi,NATURE MEDICINE,NATURE PUBLISHING GROUP,Vol. 12,No. 12,p. 1358-1359,2006年12月
  • Regulatory T cells,Shimon Sakaguchi,SPRINGER SEMINARS IN IMMUNOPATHOLOGY,SPRINGER,Vol. 28,No. 1,p. 1-2,2006年09月
  • Spontaneous development of autoimmune arthritis due to genetic anomaly of T cell signal transduction: Part 1,Shimon Sakaguchi,Noriko Sakaguchi,Hiroyuki Yoshitomi,Hiroshi Hata,Takeshi Takahashi,Takashi Nomura,SEMINARS IN IMMUNOLOGY,ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD,Vol. 18,No. 4,p. 199-206,2006年08月,書評論文,書評,文献紹介等
  • Regulatory T cells: Meden Agan,Shimon Sakaguchi,IMMUNOLOGICAL REVIEWS,BLACKWELL PUBLISHING,Vol. 212,p. 5-7,2006年08月
  • Emerging possibilities in the development and function of regulatory T cells,Kajsa Wing,Zoltán Fehérvári,Shimon Sakaguchi,International Immunology,Vol. 18,No. 7,p. 991-1000,2006年07月,書評論文,書評,文献紹介等
  • リウマチと骨関節破壊 SKGマウス ZAP-70遺伝子変異による関節リウマチモデルマウス,坂口 教子,野村 尚史,畑 洋,吉富 啓之,田中 聡,廣田 圭司,坂口 志文,日本骨代謝学会学術集会プログラム抄録集,(一社)日本骨代謝学会,Vol. 24回,p. 105-105,2006年07月
  • Regulatory T cells in immune surveillance and treatment of cancer,Tomoyuki Yamaguchi,Shimon Sakaguchi,Seminars in Cancer Biology,Vol. 16,No. 2,p. 115-123,2006年04月,書評論文,書評,文献紹介等
  • The dichotomous role of IL-2: Tolerance versus immunity,Zoltán Fehérvari,Tomoyuki Yamaguchi,Shimon Sakaguchi,Trends in Immunology,Vol. 27,No. 3,p. 109-111,2006年03月,書評論文,書評,文献紹介等
  • Peacekeepers of the IMMUNE SYSTEM,Zoltan Fehervari,Shimon Sakaguchi,Scientific American,Scientific American Inc.,Vol. 295,No. 4,p. 56-63,2006年,書評論文,書評,文献紹介等
  • Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in self-tolerance and autoimmune disease,S. Sakaguchi,R. Setoguchi,H. Yagi,T. Nomura,Current Topics in Microbiology and Immunology,Vol. 305,p. 51-66,2006年,書評論文,書評,文献紹介等
  • 関節リウマチ(RA)患者におけるTCR シグナル遺伝子(ZAP-70 and CD3z chain)の遺伝子解析について,畑洋,中村孝志,塩沢俊一,三森経世,坂口教子,坂口志文,第50 回日本リウマチ学会総会・学術集会(2006.4.23- 26. 長崎),2006年
  • CD25+CD4+制御性T 細胞によるSKG マウス関節炎の治療,田中聡,橋本求,廣田圭司,吉富啓之,野村尚史,坂口教子,坂口志文,第35回日本免疫学会総会(2005. 12. 13-15 横浜),2005年12月13日
  • Animal models of arthritis caused by systemic alteration of the immune system,S Sakaguchi,N Sakaguchi,CURRENT OPINION IN IMMUNOLOGY,CURRENT BIOLOGY LTD,Vol. 17,No. 6,p. 589-594,2005年12月,書評論文,書評,文献紹介等
  • 自己免疫性関節炎を自然発症するSKGマウスにおけるCD4+T細胞の自己反応性,廣田 圭司,吉富 啓之,橋本 求,田中 聡,野村 尚史,坂口 教子,坂口 志文,日本免疫学会総会・学術集会記録,(NPO)日本免疫学会,Vol. 35,p. 243-243,2005年11月
  • CD4+ regulatory cells as a potential immunotherapy,Zoltán Fehérvari,Shimon Sakaguchi,Philosophical Transactions of the Royal Society B: Biological Sciences,Royal Society,Vol. 360,No. 1461,p. 1647-1661,2005年09月29日,書評論文,書評,文献紹介等
  • Regulatory T cells in immunologic self-tolerance and autoimmune disease,S Sakaguchi,N Sakaguchi,INTERNATIONAL REVIEWS OF IMMUNOLOGY,TAYLOR & FRANCIS INC,Vol. 24,No. 3-4,p. 211-226,2005年05月,書評論文,書評,文献紹介等
  • Naturally arising CD25+CD4+ regulatory T cells in tumor immunity,T. Nomura,S. Sakaguchi,Current Topics in Microbiology and Immunology,Vol. 293,p. 287-302,2005年,書評論文,書評,文献紹介等
  • Naturally arising Foxp3-expressing CD25+ CD4+ regulatory T cells in immunological tolerance to self and non-self,Shimon Sakaguchi,Nature Immunology,Vol. 6,No. 4,p. 345-352,2005年,書評論文,書評,文献紹介等
  • CD4+ Tregs and immune control,Zoltán Fehérvari,Shimon Sakaguchi,Journal of Clinical Investigation,Vol. 114,No. 9,p. 1209-1217,2004年11月,書評論文,書評,文献紹介等
  • CD25+CD4+制御性T細胞におけるFoxP3,CTLA-4の役割,中村 恭子,廣田 圭司,Fehervari Zoltan,山口 智之,野村 尚史,坂口 志文,日本免疫学会総会・学術集会記録,(NPO)日本免疫学会,Vol. 34,p. 137-137,2004年11月
  • ZAP-70突然変異の結果自己免疫性関節炎を自然発症するSKGマウスの末梢CD4+T細胞動態,廣田 圭司,吉富 啓之,野村 尚史,坂口 教子,坂口 志文,日本免疫学会総会・学術集会記録,(NPO)日本免疫学会,Vol. 34,p. 139-139,2004年11月
  • CD25+CD4+制御性T細胞に対するGITRLの役割と腫瘍免疫誘導,西岡 朋尚,廣田 圭司,清水 淳,坂口 志文,日本免疫学会総会・学術集会記録,(NPO)日本免疫学会,Vol. 34,p. 137-137,2004年11月
  • Foxp3: A critical regulator of the development and function of regulatory T cells,Shohei Hori,Shimon Sakaguchi,Microbes and Infection,Vol. 6,No. 8,p. 745-751,2004年07月,書評論文,書評,文献紹介等
  • Development and function of CD25+CD4+ regulatory T cells,Zoltán Fehérvari,Shimon Sakaguchi,Current Opinion in Immunology,Vol. 16,No. 2,p. 203-208,2004年04月,書評論文,書評,文献紹介等
  • Naturally arising CD4+ regulatory T cells for immunologic self-tolerance and negative control of immune responses,Shimon Sakaguchi,Annual Review of Immunology,Vol. 22,p. 531-562,2004年,書評論文,書評,文献紹介等
  • 真菌・-glucan によるSKG マウス自己免疫性関節炎の惹起,吉富啓之,田中聡,野村尚史,坂口教子,中村孝志,坂口志文,第34 回日本免疫学会学術集会(2004.12.1-3. 札幌),2004年
  • Foxp3 発現T 細胞の除去による広範な自己免疫病の誘導,小野昌弘,清水淳,山口智之,ゾルタンフェヘヴァリ,宮地良樹,坂口志文,第34 回日本免疫学会学術集会(2004.12.1-3. 札幌),2004年
  • GITRHIGHT 細胞の除去はFoxp3+T 細胞を駆逐し致死的自己免疫性心筋炎および多臓器の自己免疫病・湿疹様病変を誘導する,小野昌弘,清水淳,山口智之,ゾルタンフェヘヴァリ,宮地良樹,坂口志文,第14 回Kyoto T Cell Conference(2004.6. 4-5. 京都),2004年
  • IL-2 の機能阻害による免疫自己寛容の破綻,瀬戸口留可,掘昌平,高橋武司,坂口志文,第14 回Kyoto T Cell Conference( 2004.6.4-5. 京都),2004年
  • Naturally arising CD25+CD4+ regulatory T cells in maintaining immunologic self-tolerance and preventing autoimmune disease,T Takahashi,S Sakaguchi,CURRENT MOLECULAR MEDICINE,BENTHAM SCIENCE PUBL LTD,Vol. 3,No. 8,p. 693-706,2003年12月,書評論文,書評,文献紹介等
  • The origin of FOXP3-expressing CD4+ regulatory T cells: Thymus or periphery,Shimon Sakaguchi,Journal of Clinical Investigation,Vol. 112,No. 9,p. 1310-1312,2003年11月,書評論文,書評,文献紹介等
  • CD25+CD4+制御性T細胞(Treg)の操作による腫瘍免疫の誘導,高 貴範,野村 尚史,山崎 小百合,清水 淳,廣田 圭司,中村 恭子,千葉 勉,坂口 志文,日本免疫学会総会・学術集会記録,(NPO)日本免疫学会,Vol. 33,p. 114-114,2003年11月
  • Taming transplantation with T cells,Shimon Sakaguchi,Nature Medicine,Vol. 9,No. 9,p. 1117-1118,2003年09月01日,書評論文,書評,文献紹介等
  • Control of immune responses by naturally arising CD4+ regulatory T cells that express toll-like receptors,Shimon Sakaguchi,Journal of Experimental Medicine,Vol. 197,No. 4,p. 397-401,2003年02月17日,速報,短報,研究ノート等(学術雑誌)
  • Thymic generation and selection of CD25+CD4+ regulatory T cells: Implications of their broad repertoire and high self-reactivity for the maintenance of immunological self-tolerance,Shimon Sakaguchi,Shohei Hori,Yoshinori Fukui,Takehiko Sasazuki,Noriko Sakaguchi,Takeshi Takahashi,Bach,Novartis Foundation Symposium,Vol. 252,p. 6-23,2003年,書評論文,書評,文献紹介等
  • Regulatory cells in transplantation,Kathryn J. Wood,Hidetake Ushigome,Mahzuz Karim,Andrew Bushell,Shohei Hori,Shimon Sakaguchi,Harrison,Miller,Novartis Foundation Symposium,Vol. 252,p. 177-193,2003年,書評論文,書評,文献紹介等
  • Control of Autoimmunity by Naturally Arising Regulatory CD4+ T Cells,Shohei Hori,Takeshi Takahashi,Shimon Sakaguchi,Advances in Immunology,Academic Press Inc.,Vol. 81,p. 331-371,2003年,書評論文,書評,文献紹介等
  • The role of regulatory T cells in controlling immunologic self-tolerance,T Takahashi,S Sakaguchi,INTERNATIONAL REVIEW OR CYTOLOGY - A SURVEY OF CELL BIOLOGY, VOL 225,ACADEMIC PRESS INC,Vol. 225,p. 1-32,2003年,書評論文,書評,文献紹介等
  • Regulation of tumour immunity by CD25+ T cells,Awen Gallimore,Shimon Sakaguchi,Immunology,Vol. 107,No. 1,p. 5-9,2002年,書評論文,書評,文献紹介等
  • Policing the regulators,Shimon Sakaguchi,Nature Immunology,Vol. 2,No. 4,p. 283-284,2001年04月,書評論文,書評,文献紹介等
  • Naturally anergic and suppressive CD25(+)CD4(+) T cells as a functionally and phenotypically distinct immunoregulatory T cell subpopulation,Y Kuniyasu,T Takahashi,M Itoh,J Shimizu,G Toda,S Sakaguchi,INTERNATIONAL IMMUNOLOGY,OXFORD UNIV PRESS,Vol. 12,No. 8,p. 1145-1155,2000年08月
  • Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4,T Takahashi,T Tagami,S Yamazaki,T Uede,J Shimizu,N Sakaguchi,TW Mak,S Sakaguchi,JOURNAL OF EXPERIMENTAL MEDICINE,ROCKEFELLER UNIV PRESS,Vol. 192,No. 2,p. 303-309,2000年07月
  • Regulatory T cells: Key controllers of immunologic self-tolerance,S Sakaguchi,CELL,CELL PRESS,Vol. 101,No. 5,p. 455-458,2000年05月,書評論文,書評,文献紹介等
  • Animal models of autoimmunity and their relevance to human diseases,Shimon Sakaguchi,Current Opinion in Immunology,Elsevier Ltd,Vol. 12,No. 6,p. 684-690,2000年,書評論文,書評,文献紹介等
  • Breaking immunological tolerance to tumor cells as a novel immunotherapy for cancer,S Sakaguchi,T Takahashi,J Shimizu,CELL THERAPY,SPRINGER-VERLAG TOKYO,Vol. 5,p. 3-13,2000年
  • Induction of tumor immunity by removing CD25(+)CD4(+) T cells: A common basis between tumor immunity and autoimmunity,J Shimizu,S Yamazaki,S Sakaguchi,JOURNAL OF IMMUNOLOGY,AMER ASSOC IMMUNOLOGISTS,Vol. 163,No. 10,p. 5211-5218,1999年11月
  • Tumor rejection by in vivo administration of anti-CD25 (interleukin-2 receptor alpha) monoclonal antibody,S Onizuka,Tawara, I,J Shimizu,S Sakaguchi,T Fujita,E Nakayama,CANCER RESEARCH,AMER ASSOC CANCER RESEARCH,Vol. 59,No. 13,p. 3128-3133,1999年07月
  • Virus and autoimmunity: Induction of autoimmune disease in mice by mouse T lymphotropic virus (MTLV) destroying CD4(+) T cells,SS Morse,N Sakaguchi,S Sakaguchi,JOURNAL OF IMMUNOLOGY,AMER ASSOC IMMUNOLOGISTS,Vol. 162,No. 9,p. 5309-5316,1999年05月
  • Thymus and autoimmunity: Production of CD25(+)CD4(+) naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance,M Itoh,T Takahashi,N Sakaguchi,Y Kuniyasu,J Shimizu,F Otsuka,S Sakaguchi,JOURNAL OF IMMUNOLOGY,AMER ASSOC IMMUNOLOGISTS,Vol. 162,No. 9,p. 5317-5326,1999年05月
  • Immunologic self-tolerance maintained by CD25(+)CD4(+) naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state,T Takahashi,Y Kuniyasu,M Toda,N Sakaguchi,M Itoh,M Iwata,J Shimizu,S Sakaguchi,INTERNATIONAL IMMUNOLOGY,OXFORD UNIV PRESS,Vol. 10,No. 12,p. 1969-1980,1998年12月
  • Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation,M Asano,M Toda,N Sakaguchi,S Sakaguchi,JOURNAL OF EXPERIMENTAL MEDICINE,ROCKEFELLER UNIV PRESS,Vol. 184,No. 2,p. 387-396,1996年08月
  • T cell-mediated maintenance of natural self-tolerance: Its breakdown as a possible cause of various autoimmune diseases,S Sakaguchi,M Toda,M Asano,M Itoh,SS Morse,N Sakaguchi,JOURNAL OF AUTOIMMUNITY,ACADEMIC PRESS LTD,Vol. 9,No. 2,p. 211-220,1996年04月
  • IMMUNOLOGICAL SELF-TOLERANCE MAINTAINED BY ACTIVATED T-CELLS EXPRESSING IL-2 RECEPTOR ALPHA-CHAINS (CD25) - BREAKDOWN OF A SINGLE MECHANISM OF SELF-TOLERANCE CAUSES VARIOUS AUTOIMMUNE-DISEASES,S SAKAGUCHI,N SAKAGUCHI,M ASANO,M ITOH,M TODA,JOURNAL OF IMMUNOLOGY,AMER ASSOC IMMUNOLOGISTS,Vol. 155,No. 3,p. 1151-1164,1995年08月
  • IONIZING-RADIATION AND AUTOIMMUNITY - INDUCTION OF AUTOIMMUNE-DISEASE IN MICE BY HIGH-DOSE FRACTIONATED TOTAL LYMPHOID IRRADIATION AND ITS PREVENTION BY INOCULATING NORMAL T-CELLS,N SAKAGUCHI,K MIYAI,S SAKAGUCHI,JOURNAL OF IMMUNOLOGY,AMER ASSOC IMMUNOLOGISTS,Vol. 152,No. 5,p. 2586-2595,1994年03月
  • INDUCTION OF AUTOIMMUNE-DISEASE IN MICE BY GERMLINE ALTERATION OF THE T-CELL RECEPTOR GENE-EXPRESSION,S SAKAGUCHI,TH ERMAK,M TODA,LJ BERG,W HO,B FAZEKAS DE ST GROTH,PA PETERSON,N SAKAGUCHI,MM DAVIS,JOURNAL OF IMMUNOLOGY,AMER ASSOC IMMUNOLOGISTS,Vol. 152,No. 3,p. 1471-1484,1994年02月
  • CONTINUOUS ADMINISTRATION OF ANTI-INTERLEUKIN-10 ANTIBODIES DELAYS ONSET OF AUTOIMMUNITY IN NZB/W F1-MICE,H ISHIDA,T MUCHAMUEL,S SAKAGUCHI,S ANDRADE,S MENON,M HOWARD,JOURNAL OF EXPERIMENTAL MEDICINE,ROCKEFELLER UNIV PRESS,Vol. 179,No. 1,p. 305-310,1994年01月,記事・総説・解説・論説等(学術雑誌)
  • CAUSES AND MECHANISM OF AUTOIMMUNE-DISEASE - CYCLOSPORINE-A AS A PROBE FOR THE INVESTIGATION,N SAKAGUCHI,S SAKAGUCHI,JOURNAL OF INVESTIGATIVE DERMATOLOGY,BLACKWELL SCIENCE INC,Vol. 98,No. 6,p. S70-S76,1992年06月
  • THYMUS AND AUTOIMMUNITY - CAPACITY OF THE NORMAL THYMUS TO PRODUCE PATHOGENIC SELF-REACTIVE T-CELLS AND CONDITIONS REQUIRED FOR THEIR INDUCTION OF AUTOIMMUNE-DISEASE,S SAKAGUCHI,N SAKAGUCHI,JOURNAL OF EXPERIMENTAL MEDICINE,ROCKEFELLER UNIV PRESS,Vol. 172,No. 2,p. 537-545,1990年08月
  • ORGAN-SPECIFIC AUTOIMMUNE-DISEASE INDUCED IN MICE BY ELIMINATION OF T-CELL SUBSETS .5. NEONATAL ADMINISTRATION OF CYCLOSPORINE-A CAUSES AUTOIMMUNE-DISEASE,S SAKAGUCHI,N SAKAGUCHI,JOURNAL OF IMMUNOLOGY,AMER ASSOC IMMUNOLOGISTS,Vol. 142,No. 2,p. 471-480,1989年01月
  • THYMUS AND AUTOIMMUNITY - TRANSPLANTATION OF THE THYMUS FROM CYCLOSPORIN-A-TREATED MICE CAUSES ORGAN-SPECIFIC AUTOIMMUNE-DISEASE IN ATHYMIC NUDE-MICE,S SAKAGUCHI,N SAKAGUCHI,JOURNAL OF EXPERIMENTAL MEDICINE,ROCKEFELLER UNIV PRESS,Vol. 167,No. 4,p. 1479-1485,1988年04月
  • IMMUNOLOGICAL AND CLINICAL-STUDIES ON MURINE EXPERIMENTAL AUTOIMMUNE GASTRITIS INDUCED BY NEONATAL THYMECTOMY,K FUKUMA,S SAKAGUCHI,K KURIBAYASHI,WL CHEN,R MORISHITA,K SEKITA,H UCHINO,T MASUDA,GASTROENTEROLOGY,W B SAUNDERS CO,Vol. 94,No. 2,p. 274-283,1988年02月
  • ORGAN-SPECIFIC AUTOIMMUNE-DISEASE INDUCED IN MICE - ONTOGENIC DIFFERENCES OF REGULATORY T-CELLS AND EFFECTOR T-CELLS,S SAKAGUCHI,N SAKAGUCHI,NR ROSE,FEDERATION PROCEEDINGS,FEDERATION AMER SOC EXP BIOL,Vol. 44,No. 4,p. 957-957,1985年,研究発表ペーパー・要旨(国際会議)
  • EFFECTOR MECHANISMS OF SYNGENEIC ANTI-TUMOR RESPONSES IN MICE .2. CYTO-TOXIC LYMPHOCYTES-T MEDIATE NEUTRALIZATION AND REJECTION OF RADIATION-INDUCED LEUKEMIA RL-MALE-1 IN THE NUDE-MOUSE SYSTEM,A KEYAKI,K KURIBAYASHI,S SAKAGUCHI,T MASUDA,J YAMASHITA,H HANDA,E NAKAYAMA,IMMUNOLOGY,BLACKWELL SCIENCE LTD,Vol. 56,No. 1,p. 141-151,1985年
  • EFFECTOR MECHANISMS OF SYNGENEIC ANTI-TUMOR RESPONSES IN MICE .1. ESTABLISHMENT AND CHARACTERIZATION OF AN EXOGENOUS IL-2-INDEPENDENT CYTO-TOXIC LYMPHOCYTE-T LINE SPECIFIC FOR RADIATION-INDUCED LEUKEMIA RL-MALE-1,K KURIBAYASHI,A KEYAKI,S SAKAGUCHI,T MASUDA,IMMUNOLOGY,BLACKWELL SCIENCE LTD,Vol. 56,No. 1,p. 127-140,1985年
  • ORGAN-SPECIFIC AUTOIMMUNE-DISEASES INDUCED IN MICE BY ELIMINATION OF T-CELL SUBSET .1. EVIDENCE FOR THE ACTIVE PARTICIPATION OF T-CELLS IN NATURAL SELF-TOLERANCE - DEFICIT OF A T-CELL SUBSET AS A POSSIBLE CAUSE OF AUTOIMMUNE-DISEASE,S SAKAGUCHI,K FUKUMA,K KURIBAYASHI,T MASUDA,JOURNAL OF EXPERIMENTAL MEDICINE,ROCKEFELLER UNIV PRESS,Vol. 161,No. 1,p. 72-87,1985年
  • A CLONED CELL-LINE, MK1, POSSESSING IA ANTIGENS AND ACCESSORY CELL-ACTIVITY,S KYOIZUMI,N NORO,K TESHIGAWARA,S SAKAGUCHI,T MASUDA,JOURNAL OF IMMUNOLOGY,AMER ASSOC IMMUNOLOGISTS,Vol. 128,No. 6,p. 2586-2594,1982年
  • STUDY ON CELLULAR EVENTS IN POSTTHYMECTOMY AUTOIMMUNE OOPHORITIS IN MICE .1. REQUIREMENT OF LYT-1 EFFECTOR-CELLS FOR OOCYTES DAMAGE AFTER ADOPTIVE TRANSFER,S SAKAGUCHI,T TAKAHASHI,Y NISHIZUKA,JOURNAL OF EXPERIMENTAL MEDICINE,ROCKEFELLER UNIV PRESS,Vol. 156,No. 6,p. 1565-1576,1982年
  • STUDY ON CELLULAR EVENTS IN POST-THYMECTOMY AUTOIMMUNE OOPHORITIS IN MICE .2. REQUIREMENT OF LYT-1 CELLS IN NORMAL FEMALE MICE FOR THE PREVENTION OF OOPHORITIS,S SAKAGUCHI,T TAKAHASHI,Y NISHIZUKA,JOURNAL OF EXPERIMENTAL MEDICINE,ROCKEFELLER UNIV PRESS,Vol. 156,No. 6,p. 1577-1586,1982年
  • EARLIER APPEARANCE OF MURINE MAMMARY-TUMOR VIRUS-ASSOCIATED ANTIGENS IN DUCT-ALVEOLUS NODULES INDUCED BY TRANSPLANTATION OF FETAL SALIVARY MESENCHYME INTO C3H MOUSE MAMMARY-GLANDS,S SAKAGUCHI,T TAKAHASHI,T SAKAKURA,Y SAKAGAMI,Y NISHIZUKA,H TANAKA,GANN,JAPAN CANCER ASSN CANCER INST,Vol. 72,No. 6,p. 982-987,1981年,記事・総説・解説・論説等(学術雑誌)

作品

  • (特許)腫瘍細胞に対する免疫寛容を破ることによる新しい癌免疫療法,1997年 ~
  • A new method of cancer immunotherapy by breaking immunologic tolerance to cancer cells,1997年 ~
  • (特許)リウマチ様関節炎を自然発症するマウスモデル,1996年 ~
  • Mouse model of rheumatoid arthritis,1996年 ~

委員歴

  • 学協会,日本免疫学会,運営委員,1996年 ~ 2000年