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NMR Characterization of the Papain-like Protease from SARS-CoV-2 Identifies the Conformational Heterogeneity in Its Inhibitor-Binding Site
Yutaro Shiraishi, Ichio Shimada
Journal of the American Chemical Society 2023年8月2日 研究論文(学術雑誌)
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Biphasic activation of β-arrestin 1 upon interaction with a GPCR revealed by methyl-TROSY NMR
Yutaro Shiraishi, Yutaka Kofuku, Takumi Ueda, Shubhi Pandey, Hemlata Dwivedi-Agnihotri, Arun K. Shukla, Ichio Shimada
Nature Communications Vol. 12 No. 1 p. 7158-7158 2021年12月 研究論文(学術雑誌)
出版者・発行元:Springer Science and Business Media LLC
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Function-Related Dynamics in Multi-Spanning Helical Membrane Proteins Revealed by Solution NMR
Koh Takeuchi, Yutaka Kofuku, Shunsuke Imai, Takumi Ueda, Yuji Tokunaga, Yuki Toyama, Yutaro Shiraishi, Ichio Shimada
Membranes Vol. 11 No. 8 p. 604-604 2021年8月9日 研究論文(学術雑誌)
出版者・発行元:{MDPI} {AG}
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Activation of adenosine A<inf>2A</inf> receptor by lipids from docosahexaenoic acid revealed by NMR
Mizumura, T., Kondo, K., Kurita, M., Kofuku, Y., Natsume, M., Imai, S., Shiraishi, Y., Ueda, T., Shimada, I.
Science Advances Vol. 6 No. 12 p. eaay8544-eaay8544 2020年 研究論文(学術雑誌)
出版者・発行元:American Association for the Advancement of Science (AAAS)
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Structural equilibrium underlying ligand-dependent activation of β<inf>2</inf>-adrenoreceptor
Imai, S., Yokomizo, T., Kofuku, Y., Shiraishi, Y., Ueda, T., Shimada, I.
Nature Chemical Biology Vol. 16 No. 4 p. 430-439 2020年 研究論文(学術雑誌)
出版者・発行元:Springer Science and Business Media LLC
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Function-related conformational dynamics of G protein–coupled receptors revealed by NMR
Ueda, T., Kofuku, Y., Okude, J., Imai, S., Shiraishi, Y., Shimada, I.
Biophysical Reviews Vol. 11 No. 3 p. 409-418 2019年 研究論文(学術雑誌)
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Deuteration and selective labeling of alanine methyl groups of β<inf>2</inf>-adrenergic receptor expressed in a baculovirus-insect cell expression system
Kofuku, Y., Yokomizo, T., Imai, S., Shiraishi, Y., Natsume, M., Itoh, H., Inoue, M., Nakata, K., Igarashi, S., Yamaguchi, H., Mizukoshi, T., Suzuki, E.-I., Ueda, T., Shimada, I.
Journal of Biomolecular NMR Vol. 71 No. 3 p. 185-192 2018年 研究論文(学術雑誌)
出版者・発行元:Springer Science and Business Media LLC
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Phosphorylation-induced conformation of β<inf>2</inf>-adrenoceptor related to arrestin recruitment revealed by NMR
Shiraishi, Y., Natsume, M., Kofuku, Y., Imai, S., Nakata, K., Mizukoshi, T., Ueda, T., Iwaï, H., Shimada, I.
Nature Communications Vol. 9 No. 1 p. 194-194 2018年 研究論文(学術雑誌)
出版者・発行元:Springer Science and Business Media LLC
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Identification of a Conformational Equilibrium That Determines the Efficacy and Functional Selectivity of the μ-Opioid Receptor
Okude, J., Ueda, T., Kofuku, Y., Sato, M., Nobuyama, N., Kondo, K., Shiraishi, Y., Mizumura, T., Onishi, K., Natsume, M., Maeda, M., Tsujishita, H., Kuranaga, T., Inoue, M., Shimada, I.
Angewandte Chemie - International Edition Vol. 54 No. 52 p. 15771-15776 2015年 研究論文(学術雑誌)
出版者・発行元:Wiley
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Elucidation of the CCR1- and CCR5-binding modes of MIP-1α by application of an NMR spectra reconstruction method to the transferred cross-saturation experiments
Yoshiura, C., Ueda, T., Kofuku, Y., Matsumoto, M., Okude, J., Kondo, K., Shiraishi, Y., Shimada, I.
Journal of Biomolecular NMR Vol. 63 No. 4 p. 333-340 2015年 研究論文(学術雑誌)
出版者・発行元:Springer Science and Business Media LLC
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Development of a method for reconstruction of crowded NMR spectra from undersampled time-domain data
Ueda, T., Yoshiura, C., Matsumoto, M., Kofuku, Y., Okude, J., Kondo, K., Shiraishi, Y., Takeuchi, K., Shimada, I.
Journal of Biomolecular NMR Vol. 62 No. 1 p. 31-41 2015年 研究論文(学術雑誌)
出版者・発行元:Springer Science and Business Media LLC
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Functional dynamics of deuterated β<inf>2</inf>-adrenergic receptor in lipid bilayers revealed by NMR spectroscopy
Kofuku, Y., Ueda, T., Okude, J., Shiraishi, Y., Kondo, K., Mizumura, T., Suzuki, S., Shimada, I.
Angewandte Chemie - International Edition Vol. 53 No. 49 p. 13376-13379 2014年 研究論文(学術雑誌)
出版者・発行元:Wiley
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Efficacy of the β 2-adrenergic receptor is determined by conformational equilibrium in the transmembrane region
Kofuku, Y., Ueda, T., Okude, J., Shiraishi, Y., Kondo, K., Maeda, M., Tsujishita, H., Shimada, I.
Nature Communications Vol. 3 No. 1 p. 1045-1045 2012年 研究論文(学術雑誌)
出版者・発行元:Springer Science and Business Media LLC