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NMR Characterization of the Papain-like Protease from SARS-CoV-2 Identifies the Conformational Heterogeneity in Its Inhibitor-Binding Site
Yutaro Shiraishi, Ichio Shimada
Journal of the American Chemical Society 2023/08/02 Research paper (scientific journal)
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Biphasic activation of β-arrestin 1 upon interaction with a GPCR revealed by methyl-TROSY NMR
Yutaro Shiraishi, Yutaka Kofuku, Takumi Ueda, Shubhi Pandey, Hemlata Dwivedi-Agnihotri, Arun K. Shukla, Ichio Shimada
Nature Communications Vol. 12 No. 1 p. 7158-7158 2021/12 Research paper (scientific journal)
Publisher: Springer Science and Business Media LLC
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Function-Related Dynamics in Multi-Spanning Helical Membrane Proteins Revealed by Solution NMR
Koh Takeuchi, Yutaka Kofuku, Shunsuke Imai, Takumi Ueda, Yuji Tokunaga, Yuki Toyama, Yutaro Shiraishi, Ichio Shimada
Membranes Vol. 11 No. 8 p. 604-604 2021/08/09 Research paper (scientific journal)
Publisher: {MDPI} {AG}
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Activation of adenosine A<inf>2A</inf> receptor by lipids from docosahexaenoic acid revealed by NMR
Mizumura, T., Kondo, K., Kurita, M., Kofuku, Y., Natsume, M., Imai, S., Shiraishi, Y., Ueda, T., Shimada, I.
Science Advances Vol. 6 No. 12 p. eaay8544-eaay8544 2020 Research paper (scientific journal)
Publisher: American Association for the Advancement of Science (AAAS)
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Structural equilibrium underlying ligand-dependent activation of β<inf>2</inf>-adrenoreceptor
Imai, S., Yokomizo, T., Kofuku, Y., Shiraishi, Y., Ueda, T., Shimada, I.
Nature Chemical Biology Vol. 16 No. 4 p. 430-439 2020 Research paper (scientific journal)
Publisher: Springer Science and Business Media LLC
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Function-related conformational dynamics of G protein–coupled receptors revealed by NMR
Ueda, T., Kofuku, Y., Okude, J., Imai, S., Shiraishi, Y., Shimada, I.
Biophysical Reviews Vol. 11 No. 3 p. 409-418 2019 Research paper (scientific journal)
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Deuteration and selective labeling of alanine methyl groups of β<inf>2</inf>-adrenergic receptor expressed in a baculovirus-insect cell expression system
Kofuku, Y., Yokomizo, T., Imai, S., Shiraishi, Y., Natsume, M., Itoh, H., Inoue, M., Nakata, K., Igarashi, S., Yamaguchi, H., Mizukoshi, T., Suzuki, E.-I., Ueda, T., Shimada, I.
Journal of Biomolecular NMR Vol. 71 No. 3 p. 185-192 2018 Research paper (scientific journal)
Publisher: Springer Science and Business Media LLC
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Phosphorylation-induced conformation of β<inf>2</inf>-adrenoceptor related to arrestin recruitment revealed by NMR
Shiraishi, Y., Natsume, M., Kofuku, Y., Imai, S., Nakata, K., Mizukoshi, T., Ueda, T., Iwaï, H., Shimada, I.
Nature Communications Vol. 9 No. 1 p. 194-194 2018 Research paper (scientific journal)
Publisher: Springer Science and Business Media LLC
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Identification of a Conformational Equilibrium That Determines the Efficacy and Functional Selectivity of the μ-Opioid Receptor
Okude, J., Ueda, T., Kofuku, Y., Sato, M., Nobuyama, N., Kondo, K., Shiraishi, Y., Mizumura, T., Onishi, K., Natsume, M., Maeda, M., Tsujishita, H., Kuranaga, T., Inoue, M., Shimada, I.
Angewandte Chemie - International Edition Vol. 54 No. 52 p. 15771-15776 2015 Research paper (scientific journal)
Publisher: Wiley
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Elucidation of the CCR1- and CCR5-binding modes of MIP-1α by application of an NMR spectra reconstruction method to the transferred cross-saturation experiments
Yoshiura, C., Ueda, T., Kofuku, Y., Matsumoto, M., Okude, J., Kondo, K., Shiraishi, Y., Shimada, I.
Journal of Biomolecular NMR Vol. 63 No. 4 p. 333-340 2015 Research paper (scientific journal)
Publisher: Springer Science and Business Media LLC
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Development of a method for reconstruction of crowded NMR spectra from undersampled time-domain data
Ueda, T., Yoshiura, C., Matsumoto, M., Kofuku, Y., Okude, J., Kondo, K., Shiraishi, Y., Takeuchi, K., Shimada, I.
Journal of Biomolecular NMR Vol. 62 No. 1 p. 31-41 2015 Research paper (scientific journal)
Publisher: Springer Science and Business Media LLC
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Functional dynamics of deuterated β<inf>2</inf>-adrenergic receptor in lipid bilayers revealed by NMR spectroscopy
Kofuku, Y., Ueda, T., Okude, J., Shiraishi, Y., Kondo, K., Mizumura, T., Suzuki, S., Shimada, I.
Angewandte Chemie - International Edition Vol. 53 No. 49 p. 13376-13379 2014 Research paper (scientific journal)
Publisher: Wiley
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Efficacy of the β 2-adrenergic receptor is determined by conformational equilibrium in the transmembrane region
Kofuku, Y., Ueda, T., Okude, J., Shiraishi, Y., Kondo, K., Maeda, M., Tsujishita, H., Shimada, I.
Nature Communications Vol. 3 No. 1 p. 1045-1045 2012 Research paper (scientific journal)
Publisher: Springer Science and Business Media LLC
