EN

基本情報

研究

社会活動

その他の活動

菊地 和也

Kikuchi Kazuya

工学研究科 応用化学専攻,教授

keyword ケミカルバイオロジー

学歴

  • ~ 1994年03月,東京大学,薬学部
  • ~ 1990年03月,東京大学,薬学系研究科
  • ~ 1988年03月,東京大学,薬学部

経歴

  • 2020年04月01日 ~ 継続中,大阪大学 工学研究科 応用化学専攻,教授
  • 2005年07月 ~ 継続中,大阪大学大学院工学研究科生命先端工学専攻・教授
  • 2005年07月01日 ~ 2020年03月31日,大阪大学 工学研究科 生命先端工学専攻,教授
  • 2000年12月 ~ 2005年06月,東京大学大学院薬学系研究科・助教授
  • 1997年01月 ~ 2000年11月,東京大学大学院薬学系研究科・助手
  • 1995年07月 ~ 1996年12月,スクリプス研究所リサーチアソシエイト
  • 1994年07月 ~ 1995年06月,カリフォルニア大学サンディエゴ校博士研究員

研究内容・専門分野

  • ナノテク・材料,生物分子化学

所属学会

  • 米国化学会
  • 日本薬学会
  • 日本化学会

論文

  • Anti-Siglec-15 antibody suppresses bone resorption by inhibiting osteoclast multinucleation without attenuating bone formation,Hiroyuki Tsukazaki,Junichi Kikuta,Tomoka Ao,Akito Morimoto,Chie Fukuda,Eisuke Tsuda,Masafumi Minoshima,Kazuya Kikuchi,Takashi Kaito,Masaru Ishii,Bone,Elsevier BV,Vol. 152,p. 116095-116095,2021年11月,研究論文(学術雑誌)
  • Cardioluminescence in Transgenic Zebrafish Larvae: A Calcium Imaging Tool to Study Drug Effects and Pathological Modeling,Manuel Vicente,Jussep Salgado-Almario,Michelle M. Collins,Antonio Martínez-Sielva,Masafumi Minoshima,Kazuya Kikuchi,Beatriz Domingo,Juan Llopis,Biomedicines,MDPI AG,Vol. 9,No. 10,p. 1294-1294,2021年09月22日,研究論文(学術雑誌)
  • Development of Off-On Switching 19F MRI Probes for Cathepsin K Activity Detection,Yuki Konishi,Atsuya Okunishi,Fuminori Sugihara,Tatsuya Nakamura,Kazuki Akazawa,Masafumi Minoshima,Kazuya Kikuchi,Bulletin of the Chemical Society of Japan,The Chemical Society of Japan,Vol. 94,No. 6,p. 1690-1694,2021年04月27日,研究論文(学術雑誌)
  • Optical manipulation of subcellular protein translocation using a photoactivatable covalent labeling system,Angewandte Chemie International Edition,Vol. 60,No. 20,p. 11378-11383,2021年02月28日,研究論文(学術雑誌)
  • A step towards gadolinium-free bioresponsive MRI contrast agent,Marzena Wyskocka-Gajda,Łukasz Przypis,Monika Olesiejuk,Tomasz Krawczyk,Anna Kuźnik,Krzysztof Nawara,Masafumi Minoshima,Fuminori Sugihara,Kazuya Kikuchi,Nikodem Kuźnik,European Journal of Medicinal Chemistry,Elsevier BV,Vol. 211,p. 113086-113086,2021年02月,研究論文(学術雑誌)
  • Near-infrared fluorescent probes: a next-generation tool for protein-labeling applications,Shahi Imam Reja,Masafumi Minoshima,Yuichiro Hori,Kazuya Kikuchi,Chemical Science,Royal Society of Chemistry (RSC),2021年,研究論文(学術雑誌)
  • Fluorogenic probes for detecting deacylase and demethylase activity towards post-translationally-modified lysine residues,Chemical Science,Vol. 12,No. 7,p. 2498-2503,2021年,研究論文(学術雑誌)
  • Single-cell dynamics of pannexin-1-facilitated programmed ATP loss during apoptosis,eLife,Vol. 9,p. 1-20,2020年10月14日,研究論文(学術雑誌)
  • Oxygen Functional Groups on MWCNT Surface as Critical Factor Boosting T2 Relaxation Rate of Water Protons: Towards Improved CNT-Based Contrast Agents.,Tomczyk MM,Boncel S,Herman A,Krawczyk T,Jakóbik-Kolon A,Pawlyta M,Krzywiecki M,Chrobak A,Minoshima M,Sugihara F,Kikuchi K,Kuźnik N,Int J Nanomedicine.,Vol. 2020,No. 15,p. 7433-7450,2020年10月,研究論文(学術雑誌)
  • An Acid Activatable Fluorescence Probe for Imaging Osteocytic Bone Resorption Activity in Deep Bone Cavities,R. Hashimoto,M. Minoshima,J. Kikuta,S. D. Bull,M. Ishii,K. Kikuchi,Angew. Chem. Int. Ed.,Vol. 59,p. 20996-21000,2020年08月,研究論文(学術雑誌)
  • A Photoactivatable Antagonist for Controlling CREB Dependent Gene Expression,T. Imoto,M. Minoshima,T. Yokoyama,B. P. Emery,S. D. Bull,H. Bito,K. Kikuchi,ACS Cent. Sci.,Vol. 6,No. 10,p. 1813-1818,2020年08月,研究論文(学術雑誌)
  • Rapid No-wash Labeling of PYP-tag Proteins with Reactive Fluorogenic Ligands Affords Stable Fluorescent Protein Conjugates for Long-Term Cell Imaging Studies,N. Kumar,Y. Hori,M. Nishiura,K. Kikuchi,Chem. Sci.,Vol. 2020,No. 11,p. 3694-3701,2020年05月,研究論文(学術雑誌)
  • Development of photoswitchable fluorescent molecules using arylazopyrazole,K. Torii,Y. Hori,K. Watabe,K. Kikuchi,Bull. Chem. Soc. Jpn.,Vol. 93,No. 7,p. 821-824,2020年05月,研究論文(学術雑誌)
  • Direct visualization of an antidepressant analog using surface-enhanced Raman scattering in the brain,Masato Tanuma,Atsushi Kasai,Kazuki Bando,Naoyuki Kotoku,Kazuo Harada,Masafumi Minoshima,Kosuke Higashino,Atsushi Kimishima,Masayoshi Arai,Yukio Ago,Kaoru Seiriki,Kazuya Kikuchi,Satoshi Kawata,Katsumasa Fujita,Hitoshi Hashimoto,JCI Insight,American Society for Clinical Investigation,Vol. 5,No. 6,2020年03月,研究論文(学術雑誌)
  • Sensing Peroxynitrite in Different Organelles of Murine RAW264.7 Macrophages with Coumarin-Based Fluorescent Probes,M. Weber,N. Yamada,X. Tian,S. D. Bull,M. Minoshima,K. Kikuchi,A. B. Mackenzie,T. D. James,Front. Chem.,2020年02月,研究論文(学術雑誌)
  • Engineered Protein-Tag for Rapid Live-Cell Fluorogenic Visualization of Proteins by Anionic Probes,Jingchi Gao,Yuichiro Hori,Miyako Nishiura,Mathieu Bordy,Jens Hasserodt,Kazuya Kikuchi,Chem. Lett.,Vol. 49,No. 3,p. 232-235,2020年01月,研究論文(学術雑誌)
  • Live-Cell Imaging of Protein Degradation Utilizing Designed Protein-Tag Mutant and Fluorescent Probe with Turn-Off Switch,Jingchi Gao,Yuichiro Hori,Osamu Takeuchi,Kazuya Kikuchi,Bioconjugate Chem.,Vol. 31,No. 3,p. 577-583,2019年12月,研究論文(学術雑誌)
  • Development of Fluorogenic Probes for Rapid High-Contrast Imaging of Transient Nuclear Localization of Sirtuin 3,J. Gao,Y. Hori,T. Shimonura,M. Bordy,J. Hasserodt,K. Kikuchi,ChemBioChem,,2019年12月,研究論文(学術雑誌)
  • Improvement in Photostability of Fluorescein by Lanthanide Ions Based on Energy Transfer-based Triplet State Quenching,T. Imoto,M. Muramatsu,H. Miyasaka,S. Mizukami,K. Kikuchi,Chem. Lett.,,Vol. 48,No. 10,p. 1181-1184,2019年12月,研究論文(学術雑誌)
  • Photolytic Release of a Caged Inhibitor of an Endogenous Transcription Factor Enables Optochemical Control of CREB Gene Expression,T. Imoto,A. Kawase,M. Minoshima,T. Yokoyama,H. Bito,K. Kikuchi,Organic Letters,2019年12月,研究論文(学術雑誌)
  • Chemical Tools with Fluorescence Switches for Verifying Epigenetic Modifications,Y. Hori,K. Kikuchi,Acc. Chem. Res.,2019年12月,研究論文(学術雑誌)
  • Photoactive Yellow Protein and its Chemical Probes: an Approach to Protein Labelling in Living Cells,N. Kumar,Y. Hori,K. Kikuchi,J. Biochem,2019年12月,研究論文(学術雑誌)
  • Development of an effective protein-labeling system based on smart fluorogenic probes,Shahi Imam Reja,Masafumi Minoshima,Yuichiro Hori,Kazuya Kikuchi,Journal of Biological Inorganic Chemistry,Vol. 24,No. 4,p. 443-455,2019年06月,研究論文(学術雑誌)
  • Development of an effective protein-labeling system based on smart fluorogenic probes,Shahi Imam Reja,Masafumi Minoshima,Yuichiro Hori,Kazuya Kikuchi,Journal of Biological Inorganic Chemistry,Vol. 24,No. 4,p. 443-455,2019年06月,研究論文(学術雑誌)
  • In Vivo Multicolor Imaging with Fluorescent Probes Revealed the Dynamics and Function of Osteoclast Proton Pumps.,Masafumi Minoshima,Junichi Kikuta,Yuta Omori,Shigeto Seno,Riko Suehara,Hiroki Maeda,Hideo Matsuda,Masaru Ishii,Kazuya Kikuchi,ACS central science,Vol. 5,No. 6,p. 1059-1066,2019年06月,研究論文(学術雑誌)
  • SCOTfluors Small, Conjugatable, Orthogonal, and Tunable Fluorophores for In Vivo Imaging of Cell Metabolism,S. Benson,A. Fernandez,N. D. Barth,F. de Moliner,M. H. Horrocks,C. S. Herrington,J. L. Abad,A. Delgado,L. Kelly,Z. Chang,Y. Feng,M. Nishiura,Y. Hori,K. Kikuchi,M. Vendrell,Angew. Chem. Int. Ed.,2019年03月,研究論文(学術雑誌)
  • Ratiometric Imaging of Intracellular Mg2+ Dynamics Using a Red Fluorescent Turn-off Probe and a Green Fluorescent Turn-on Probe,Yusuke Matsui,Shin Mizukami,Kazuya Kikuchi,Chem. Lett.,2018年12月,研究論文(学術雑誌)
  • Synthetic-Molecule/Protein Hybrid Probe with Fluorogenic Switch for Live-Cell Imaging of DNA Methylation,Yuichiro Hori,Norimichi Otomura,Ayuko Nishida,Miyako Nishiura,Maho Umeno,Isao Suetake,Kazuya Kikuchi,J. Am. Chem. Soc.,,Vol. 140,No. 5,p. 1686-1690,2018年12月,研究論文(学術雑誌)
  • Direct Cell-cell Contact Between Mature Osteoblasts and Osteoclasts Dynamically Controls Their Fucntions In Vivo,Masayuki Furuya,Junichi Kikuta,Sayumi Fujimori,Shigeto Seno,Hiroki Maeda,Mai Shirazaki,Maki Uenaka,Hiroki Mizuno,Yoriko Iwamoto,Akito Morimoto,Kunihiko Hashimoto,Takeshi Ito,Yukihiro Isogai,Masafumi Kashii,Takashi Kaito,Shinsuke Ohba,Ung-il Chung,Alexander C. Lichtler,Kazuya Kikuchi,Hideo Matsuda,Hideki Yoshikawa,Masaru Ishii,Nat. Commun,2018年12月,研究論文(学術雑誌)
  • Perfluorocarbon-based 19F MRI Nanoprobes for In Vivo Multicolor Imaging,K. Akazawa,F. Sugihara,T. Nakamura,H. Matsushita,H. Mukai,R. Akimoto,M. Minoshima,S. Mizukami,K. Kikuchi,Angewante Chemie International Edition,Vol. 57,No. 51,p. 16742-16747,2018年12月,研究論文(学術雑誌)
  • Ratiometric Imaging of Intracellular Mg2+ Dynamics Using a Red Fluorescent Turn-off Probe and a Green Fluorescent Turn-on Probe,Yusuke Matsui,Shin Mizukami,Kazuya Kikuchi,Chem. Lett.,2018年12月,研究論文(学術雑誌)
  • Sensing caspase-1 activity using activatable <sup>19</sup>F MRI nanoprobes with improved turn-on kinetics.,Akazawa K,Sugihara F,Minoshima M,Mizukami S,Kikuchi K,Chemical communications (Cambridge, England),Vol. 54,No. 83,p. 11785-11788,2018年10月,研究論文(学術雑誌)
  • In vivo visualisation of different modes of action of biological DMARDs inhibiting osteoclastic bone resorption,Yoshinobu Matsuura,Junichi Kikuta,Yuika Kishi,Tetsuo Hasegawa,Daisuke Okuzaki,Toru Hirano,Masafumi Minoshima,Kazuya Kikuchi,Atsushi Kumanogoh,Masaru Ishii,ANNALS OF THE RHEUMATIC DISEASES,BMJ PUBLISHING GROUP,Vol. 77,No. 8,p. 1220-1226,2018年08月,研究論文(学術雑誌)
  • Dynamic Analyses of the Short‐term Effects of Different Bisphosphonates Using Intravital Two‐photon Microscopy,Junichi Kikuta,Mai Shirazaki,Takao Sudo,Hiroki Mizuno,Akito Morimoto,Riko Suehara,Masafumi Minoshima,Kazuya Kikuchi,Masaru Ishii,JBMR PLUS,Vol. 2,No. 6,p. 362-366,2018年05月,研究論文(学術雑誌)
  • Live-Cell Imaging of DNA Methylation Based on Synthetic-Molecule/Protein Hybrid Probe,Kumar, N,Hori, Y,Kikuchi, K,Chem. Rec.,Vol. 18,No. 12,p. 1672-1680,2018年04月,研究論文(学術雑誌)
  • In vivo Visualization of Different Modes of Action of Biologic DMARDs Inhibiting Osteoclastic Bone Resorption,Y. Matsuura,J. Kikuta,Y. Kishi,T. Hasegawa,D. Okuzaki,T. Hirano,M. Minoshima,K. Kikuchi,A. Kumanogoh,M. Ishii,Ann. Rheum. Dis.,Vol. 77,p. 1219-1225,2018年04月,研究論文(学術雑誌)
  • 生体骨イメージングのプローブ開発 ~破骨細胞活性をイメージングする蛍光プローブ,蓑島維文,菊地和也,Clinical Calcium,2018年02月
  • Highly Sensitive Detection of Caspase-3/7 Activity in Living Mice Using Enzyme-Responsive 19F MRI Nanoprobes,K. Aakazawa,F. Sugihara,T. Nakamura,S. Mizukami,K. Kikuchi,Bioconjug. Chem.,,2018年01月,研究論文(学術雑誌)
  • Intracellular Protein Labeling Probes for Multicolor Single-molecule Imaging of Immune Receptor-adaptor Molecular Dynamics,Ryota Sato,Jun Kozuka,Masahiro Ueda,Reiko Mishima,Yutaro Kumagai,Akimasa Yoshimura,Masafumi Minoshima,Shin Mizukami,Kazuya Kikuchi,Journal of the American Chemical Society,Vol. 139,p. 17397-17404,2017年11月,研究論文(学術雑誌)
  • Intracellular protein-labeling probes for multicolor single-molecule imaging of immune receptor-adaptor molecular dynamics,Sato R,Kozuka J,Ueda M,Mishima R,Kumagai Y,Yoshimura A,Minoshima M,Mizukami S,Kikuchi K,Journal of the American Chemical Society,ACS Publications,2017年11月,研究論文(学術雑誌)
  • GLUT4の細胞内動態を可視化する 化学アプローチで明らかとなった糖鎖の役割,堀 雄一郎,菊地 和也,化学と生物,2017年10月
  • 生細胞でのタンパク質蛍光標識技術の開発と糖鎖機能の解明,堀 雄一郎,菊地 和也,生体の科学,2017年10月
  • Visualization of Long-term Mg2+ Dynamics in Apoptotic Cells Using a Novel Targetable Fluorescent Probe,Y. Matsui,Y. Funato,H. Imamura,H. Miki,S. Mizukami,K. Kikuchi,Chem. Sci.,Vol. 8,No. 12,p. 8255-8264,2017年10月,研究論文(学術雑誌)
  • Development of Multicolor Fluorogenic Probes for Elucidating Role of GLUT4 N-Glycan in Intracellular Trafficking,Hori,Y. Hirayama, H,Benedek, Z,Suzuki, T,Kikuchi, K,2017年08月,研究論文(国際会議プロシーディングス)
  • Highly Selective Tridentate Fluorescent Probes for Visualizing Intracellular Mg2+ Dynamics without Interference from Ca2+ Fluctuation,Y. Matsui,K.K. Sadhu,S. Mizukami,K. Kikuchi,Chem. Commun.,2017年08月,研究論文(学術雑誌)
  • Photostable and photoswitching fluorescent dyes for super-resolution imaging,Masafumi Minoshima,Kazuya Kikuchi,J. Biol. Inorg. Chem.,Vol. 22,p. 1-14,2017年07月
  • Development of Cyanine Probes with Dinitrobenzene Quencher for Rapid Fluorogenic Protein Labeling,Hori, Y,Hirayama, S,Kikuchi, K,Philos. Trans. R. Soc. London, Ser. A,Vol. 375,2017年04月,研究論文(学術雑誌)
  • ケミカルバイオロジーと分子イメージング,堀雄一郎,菊地和也,感染炎症免疫,2017年01月,研究論文(学術雑誌)
  • Enzyme-triggered Compound Release Using Functionalized Antimicrobial Peptide Derivatives,S. Mizuakmi,M. Kashibe,K. Yamashita,L. Jin,K. Kikuchi,Chem. Sci.,2017年01月,研究論文(学術雑誌)
  • Fluorogenic probes reveal a role of GLUT4 N-glycosylation in intracellular trafficking,Hirayama S,Hori Y,Benedek Z,Suzuki T,Kikuchi K,Nature Chemical Biology,Vol. 12,No. 10,p. 853-859,2016年10月,研究論文(学術雑誌)
  • Real-time intravital imaging of pH variation associated with osteoclast activity.,Hiroki Maeda,Toshiyuki Kowada,Junichi Kikuta,Masayuki Furuya,Mai Shirazaki,Shin Mizukami,Masaru Ishii,Kazuya Kikuchi,Nature chemical biology,NATURE PUBLISHING GROUP,Vol. 12,No. 8,p. 579-85,2016年08月,研究論文(学術雑誌)
  • Modified polysaccharides as potential (19)F magnetic resonance contrast agents,Krawczyk Tomasz,Masafumi Minoshima,Fuminori Sugihara,Kazuya Kikuchi,Carbohydrate Research,Vol. 428,p. 72-78,2016年06月,研究論文(学術雑誌)
  • Fluorogenic Probes Designed for Multicolor Live-Cell Imaging Reveal Role of GLUT4 N-Glycosylation in Intracellular Trafficking,S. Hirayama,Y. Hori,Z. Benedek,T. Suzuki,K. Kikuchi,Nature Chemical Biology,Vol. 12,p. 853-859,2016年06月,研究論文(学術雑誌)
  • Selective Labeling of Proteins on Living Cell Membranes Using Fluorescent Nanodiamond Probes,S. Sotoma,J. Iimura,R. Igarashi,K.M. Hirosawa,H. Ohnishi,S. Mizukami,K. Kikuchi,T.K. Fujiwara,M. Shirakawa,H. Tochio,Nanomaterials,2016年03月,研究論文(学術雑誌)
  • Design of a Protein Tag and Fluorogenic Probe with Modular Structure for Live-Cell Imaging of Intracellular Proteins,Kamikawa, Y,Hori, Y,Yamashita, K,Jin, L,Hirayama, S,Standley, D. M,Kikuchi, K,Chem. Sci.,Vol. 7,No. 1,p. 308-314,2016年01月,研究論文(学術雑誌)
  • Fabrication of ‘Clickable’ Polyfluorene Nanowires with High Aspect Ratio as Biological Sensing Platforms,T. Wasin,K. Enomoto,T. Sakurai,V. Padalkar,H. Cheng,M. Tang,A. Horio,D.Sakamaki,M. Omichi,A. Saeki,K. Kikuchi,Y. Hori,A. Chiba,Y. Saito,T. Kamiya,M. Sugimoto,S. Seki,ACS Sensors,2016年01月,研究論文(学術雑誌)
  • 19F MRI Probes with Tunable Switches and Highly Sensitive 19F MRI Nano-probes,K. Kikuchi,Bull. Chem. Soc. Japan,2015年12月,研究論文(学術雑誌)
  • Chemical Probes for Elucidating Histone Deacetylase Function,M. Minoshima,K. Kikuchi,Anal. Sci.,2015年12月,研究論文(学術雑誌)
  • BODIPY-based Fluorescent Probes for Biological Applications,T. Kowada,Y. Hori,K. Kikuchi,Chem. Soc. Rev.,2015年12月,研究論文(学術雑誌)
  • Redesign of a Fluorogenic Labeling System To Improve Surface Charge, Brightness, and Binding Kinetics for Imaging the Functional Localization of Bromodomains,Hori Y,Hirayama S,Sato M,Kikuchi K,Angewandte Chemie International Edition,Vol. 54,No. 48,p. 14368-14371,2015年11月,研究論文(学術雑誌)
  • An Enzyme-Responsive Metal-Enhanced Near-Infrared Fluorescence Sensor Based on Functionalized Gold Nanoparticles,Z. Zhang,S. Mizukami,K. Fujita,K. Kikuchi,Chem. Sci.,2015年06月,研究論文(学術雑誌)
  • Chemical tools for probing histone deacetylase (HDAC) activity,Masafumi Minoshima,Kazuya Kikuchi,Analytical Science,Vol. 31,No. 4,p. 287-292,2015年04月
  • Nonlinear fluorescence imaging by photoinduced charge separation,Kentaro Mochizuki,Lanting Shi,Shin Mizukami,Masahito Yamanaka,Mamoru Tanabe,Wei-Tao Gong,Almar F Palonpon,Shogo Kawano,Satoshi Kawata,Kazuya Kikuchi,Katsumasa Fujita,Japanese Journal of Applied Physics,2015年03月,研究論文(学術雑誌)
  • Intramolecular Long-Distance Nucleophilic Reactions as a Rapid Fluorogenic Switch Applicable to the Detection of Enzymatic Activity,Baba, R,Hori, Y,Kikuchi, K,Chem. Eur. J.,Vol. 21,p. 4695-4702,2015年03月,研究論文(学術雑誌)
  • Mesoporous Silica Nanoparticles for 19F Magnetic Resonance Imaging, Fluorescence Imaging, and Drug Delivery,T. Nakamaura,F. Sugihara,H. Matsushita,Y. Yoshioka,S. Mizukami,K. Kikuchi,Chem. Sci.,Vol. 6,No. 3,p. 1986-1990,2015年01月,研究論文(学術雑誌)
  • Activatable 19F MRI nanoparticle probes for the detection of reducing environments.,Nakamura T,Matsushita H,Sugihara F,Yoshioka Y,Mizukami S,Kikuchi K,Angewandte Chemie (International ed. in English),Vol. 54,No. 3,p. 1007-10,2015年01月,研究論文(学術雑誌)
  • Development of Fluorogenic Probe based on a DNA Staining Dye for Continuous Monitoring of the Histone Deacetylase Reaction,M. Minoshima,T. Matsumoto,K. Kikuchi,Anal. Chem.,2014年12月,研究論文(学術雑誌)
  • Small-Molecule-Based Protein-Labeling Technology in Live Cell Studies Probe-Design Concepts and Applications,S. Mizumkami,Y. Hori,K. Kikuchi,Acc. Chem. Res.,2014年12月,研究論文(学術雑誌)
  • Membrane protein CNNM4-dependent Mg2+ efflux suppresses tumor progression.,Funato Y,Yamazaki D,Mizukami S,Du L,Kikuchi K,Miki H,Journal of Clinical Investigation,Vol. 124,No. 12,p. 5398-5410,2014年12月,研究論文(学術雑誌)
  • Development of a Fluorogenic Probe Based on a DNA Staining Dye for Continuous Monitoring of the Histone Deacetylase Reaction,Masafumi Minoshima,Tetsuaki Matsumoto,Kazuya Kikuchi,Analytical Chemistry,Vol. 86,p. 7925-7930,2014年07月,研究論文(学術雑誌)
  • Ratiometric MRI sensors based on core-shell nanoparticles for quantitative pH imaging.,Okada S,Mizukami S,Sakata T,Matsumura Y,Yoshioka Y,Kikuchi K,Advanced materials (Deerfield Beach, Fla.),Vol. 26,No. 19,p. 2989-92,2014年05月,研究論文(学術雑誌)
  • Multifunctional Core-shell Silica Nanoparticles for Highly Sensitive 19F MRI,H. Matsushita,S. Mizukami,F. Sugihara,Y. Nakanishi,Y. Yoshioka,K. Kikuchi,Angew. Chem. Int. Ed.,Vol. 53,p. 1008-1011,2014年04月,研究論文(学術雑誌)
  • Multifunctional core–shell silica nanoparticles for highly sensitive (19)F magnetic resonance imaging.,Hisashi Matsushita,Shin Mizukami,Fuminori Sugihara,Yosuke Nakanishi,Yoshichika Yoshioka,Kazuya Kikuchi,Angewandte Chemie (International ed. in English),Vol. 53,No. 4,p. 1008-11,2014年01月20日,研究論文(学術雑誌)
  • Mg2+ efflux by CNNM4 and Its Suppression of Tumor Progression,Y. Funato,D. Yamazaki,S. Mizukami,L. Du,K. Kikuchi,H. Miki,J. Clin. Invest.,2014年01月,研究論文(学術雑誌)
  • 1H MRI Detection of Gene Expression in Living Cells by Using Protein Tag and Biotinylation Probe,A. Yoshimura,S. Mizukami,Y. Mori,Y. Yoshioka,K. Kikuchi,Chem. Lett.,2014年01月,研究論文(学術雑誌)
  • Dynamic Visualization of RANKL and Th17-mediated Control of Osteoclast Function,J. Kikuta,Y. Wada,T. Kowada,Z. Wang,G.-H. Sun-Wada,I. Nishiyama,S. Mizukami,N. Maiya,H. Yasuda,A. Kumanogoh,K. Kikuchi,R.N. Germain,M. Ishii,J. Clin. Invest.,2013年12月,研究論文(学術雑誌)
  • Basolateral Mg2+ Extrusion via CNNM4 Mediates Transcellular Mg2+ Transport across Epithelia: A Mouse Model,D. Yamazaki,Y. Funato,J. Miura,S. Sato,S. Toyosawa,K. Furutani,Y. Kurachi,Y.Omori,T. Furukawa,T. Tsuda,S. Kuwabata,S. Mizukami,K. Kikuchi,H. Miki,PLOS Genetics.,Vol. 9,No. 12,2013年12月,研究論文(学術雑誌)
  • pH Induced Dual ‘OFF-ON-OFF’ Switch: Influence of Suitably Placed Carboxylic Acid,K.K. Sadhu,S. Mizukami,A. Yoshimura,K. Kikuchi,Org. Biomol. Chem.,2013年12月,研究論文(学術雑誌)
  • Ratiometric MRI Contrast Agents Based on Core-Shell Nanoparticles for Quantitative pH Imaging,S. Okada,S. Mizukami,T. Sakata,Y. Matsumura,Y. Yoshioka,K. Kikuchi,Dalton Trans.,2013年12月,研究論文(学術雑誌)
  • Efficient Development of Luminescent Lanthanide(III) Complexes by Solid-phase Synthesis and On-resin Screening,T. Nakamura,S. Mizukami,M. Tanaka,K. Kikuchi,Chem. Asia. J.,2013年12月,研究論文(学術雑誌)
  • Development of Luminescent Coelenterazine Derivatives Activatable by b-Galactosidase for Monitoring Dual Gene Expression,E.J. Lindberg,S. Mizukami,K. Ibata,A. Miyawaki,K. Kikuchi,Chem. Eur. J.,2013年12月,研究論文(学術雑誌)
  • Development of Cell-Impermeable Coelenterazine Derivatives,E.J. Lindberg,S. Mizukami,K. Ibata,T. Fukano,A. Miyawaki,K. Kikuchi,Chem. Sci.,2013年12月,研究論文(学術雑誌)
  • pH Induced Dual ‘OFF-ON-OFF’ Switch: Influence of Suitably Placed Carboxylic Acid,K.K. Sadhu,S. Mizukami,A. Yoshimura,K. Kikuchi,Org. Biomol. Chem.,2013年12月,研究論文(学術雑誌)
  • Ratiometric MRI Contrast Agents Based on Core-Shell Nanoparticles for Quantitative pH Imaging,S. Okada,S. Mizukami,T. Sakata,Y. Matsumura,Y. Yoshioka,K. Kikuchi,Dalton Trans.,大阪大学超高圧電子顕微鏡センター,No. 42,p. 29-31,2013年12月,研究論文(学術雑誌)
  • Efficient Development of Luminescent Lanthanide(III) Complexes by Solid-phase Synthesis and On-resin Screening,T. Nakamura,S. Mizukami,M. Tanaka,K. Kikuchi,Chem. Asia. J.,2013年12月,研究論文(学術雑誌)
  • Development of Cell-Impermeable Coelenterazine Derivatives,E.J. Lindberg,S. Mizukami,K. Ibata,T. Fukano,A. Miyawaki,K. Kikuchi,Chem. Sci.,2013年12月,研究論文(学術雑誌)
  • Development of Luminescent Coelenterazine Derivatives Activatable by beta-Galactosidase for Monitoring Dual Gene Expression,E.J. Lindberg,S. Mizukami,K. Ibata,A. Miyawaki,K. Kikuchi,Chem. Eur. J.,2013年09月,研究論文(学術雑誌)
  • Protein Labeling with Fluorogenic Probes for No-Wash Live-Cell Imaging of Proteins,Hori, Y,Kikuchi, K,2013年08月
  • Development of Fluorogenic Probes for Quick No-Wash Live-Cell Imaging of Intracellular Proteins,Y. Hori,T. Norinobu,M. Sato,K. Arita,S. Shirakawa,K. Kikuchi,J. Am. Chem. Soc.,American Chemical Society,Vol. 135,2013年05月,研究論文(学術雑誌)
  • Basolateral Mg2+ Extrusion via CNNM4 Mediates Transcellular Mg2+ Transport across Epithelia: A Mouse Model,Daisuke Yamazaki,Yosuke Funato,Jiro Miura,Sunao Sato,Satoru Toyosawa,Kazuharu Furutani,Yoshihisa Kurachi,Yoshihiro Omori,Takahisa Furukawa,Tetsuya Tsuda,Susumu Kuwabata,Shin Mizukami,Kazuya Kikuchi,Hiroaki Miki,PLoS Genetics,PUBLIC LIBRARY SCIENCE,Vol. 9,No. 12,2013年04月,研究論文(学術雑誌)
  • PYPタグと発蛍光プローブを利用したタンパク質の生細胞蛍光イメージング,堀 雄一郎,菊地 和也,化学と生物,Japan Society for Bioscience, Biotechnology, and Agrochemistry,Vol. 51,No. 3,p. 189-192,2013年03月01日
  • Dynamic visualization of RANKL and Th17-mediated osteoclast function.,Junichi Kikuta,Yoh Wada,Toshiyuki Kowada,Ze Wang,Ge-Hong Sun-Wada,Issei Nishiyama,Shin Mizukami,Nobuhiko Maiya,Hisataka Yasuda,Atsushi Kumanogoh,Kazuya Kikuchi,Ronald N Germain,Masaru Ishii,The Journal of clinical investigation,Vol. 123,No. 2,p. 866-73,2013年02月,研究論文(学術雑誌)
  • A Long-Lived Luminescent Probe to Sensitively Detect Arylamine N-Acetyltransferase (NAT) Activity of Cells,T. Terai,K. Kikuchi,Y. Urano,H. Kojima,T. Nagano,Chem. Commun.,,2012年12月,研究論文(学術雑誌)
  • Salicylic Acid Derivatives as Antennae for Ratiometric Luminescent Probes Based on Lanthanide Complexes,T. Terai,H. Ito,K. Kikuchi,T. Nagano,Chem. Eur. J.,,2012年12月,研究論文(学術雑誌)
  • A New Approach for Fluorogenic Protein Labeling Via Photoinduced Electron Transfer Based BL-tag Protein Labeling Method,K.K. Sadhu,S. Mizukami,C.R. Lanam,K. Kikuchi,Chem. Asia. J.,2012年12月,研究論文(学術雑誌)
  • Switchable MRI Contrast Agents Based on Morphological Changes of pH-responsive Polymers,S. Okada,S. Mizukami,K. Kikuchi,Bioorg. Med. Chem,2012年12月,研究論文(学術雑誌)
  • 19F MRI Monitoring of Gene Expression in Living Cells via Cell Surface beta-Lactamase Activity,H. Matsushita,S. Mizukami,Y. Mori,F. Sugihara,M. Shirakawa,Y. Yoshioka,K.Kikuchi,ChemBioChem,,2012年12月,研究論文(学術雑誌)
  • Simple and Real-time Colorimetric Assay for Glycosidases Activity Using Functionalized Gold Nanoparticles and Its Application for Inhibitor Screening,Z. Zeng,S. Mizukami,K. Kikuchi,Anal. Chem.,,2012年12月,研究論文(学術雑誌)
  • Fluorescent Probe for Detection of Histone Deacetylase Activity Based on Aggregation-induced Emission,K. Dhara,Y. Hori,R. Baba,K. Kikuchi,Chem. Commun.,,2012年12月,研究論文(学術雑誌)
  • No-Wash Protein Labeling with Designed Fluorogenic Probes and Application to Real-Time Pulse-Chase Analysis,S. Mizukami,S. Watanabe,Y. Akimoto,K. Kikuchi,J. Am. Chem. Soc.,2012年12月,研究論文(学術雑誌)
  • Development of Protein Labeling Probes with Redesigned Fluorogenic Switch Based on Intramolecular Association and No-wash Live-cell Imaging,Y. Hori,K. Nakaki,M. Sato,S. Mizukami,K. Kikuchi,Angew. Chem. Int. Ed,2012年12月,研究論文(学術雑誌)
  • Fluorescent Probe for Detection of Histone Deacetylase Activity Based on Aggregation-induced Emission,K. Dhara,Y. Hori,R. Baba,K. Kikuchi,Chem. Commun.,,2012年12月,研究論文(学術雑誌)
  • Development of Fluorogenic Probe with Transesterification Switch for Detection of Histone Deacetylase Activity,R. Baba,Y. Hori,S. Mizukami,K. Kikuchi,J. Am. Chem. Soc.,2012年12月,研究論文(学術雑誌)
  • Development of Fluorogenic Probe with Transesterification switch for Detection of Histone Deacetylase Activity,Baba, R,Hori, Y,Mizukami,Kikuchi, K,J. Am. Chem. Soc.,2012年09月,研究論文(学術雑誌)
  • Development of Protein-Labeling Probes with Redesigned Fluorogenic Switch Based on Intramolecular Association for No-wash Live-cell Imaging,Hori, Y,Nakaki, K,Sato, M,Mizukami, S,Kikuchi, K,2012年09月,研究論文(学術雑誌)
  • Two Distinct Amyloid Beta-protein (Abeta) Assembly Pathways Leading to Oligomers and Fibrilsidentified by Combined Fluorescence Correlation Spectroscopy, Morphologyand Toxicity Analyses,S. Matsumura,K. Shinoda,M. Yamada,S. Yokojima,M. Inoue,T. Ohnishi,T.Shimada,K.Kikuchi,D. Masui,S. Hashimoto,M. Sato,A. Ito,M. Akioka,S. Takagi,Y. Nakamura,K.Nemoto,Y. Hasegawa,H. Takamoto,H. Inoue,S. Nakamura,Y. Nabeshima,D.B. Teplow,M. Kinjo,M. Hoshi,J. Biol. Chem.,2011年12月,研究論文(学術雑誌)
  • Cell Surface Protein Labeling with Luminescent Nanoparticles via Biotinylation Using Mutant beta-Lactamase-tag Technology,A. Yoshimura,S. Mizukami,Y. Hori,S. Watanabe,K. Kikuchi,ChemBioChem,2011年12月,研究論文(学術雑誌)
  • Sequential Ordering Among Multicolor Fluorophores for Protein Labeling Facility via Aggregation-elimination Based ß-Lactam Probes,K.K. Sadhu,S. Mizukami,S. Watanabe,K. Kikuchi,Mol. BioSyst.,2011年12月,研究論文(学術雑誌)
  • 19F MRI Detection of β-Galactosidase Activity for Imaging of Gene Expression,S. Mizukami,H. Matsushita,R. Takikawa,F. Sugihara,M. Shirakawa,K. Kikuchi,Chem. Sci.,,2011年12月,研究論文(学術雑誌)
  • Intracellular Protein Labeling with Prodrug-Like Probes Based on Mutant b-Lactamase-Tag,S. Watanabe,S. Mizukami,Y. Akimoto,Y. Hori,K. Kikuchi,Chem. Eur. J.,,2011年12月,研究論文(学術雑誌)
  • Covalent Protein Labeling with a Lanthanide Complex and its Application to Photoluminescence Lifetime-based Multicolor Bioimaging,S. Mizukami,T. Yamamoto,A. Yoshimura,S. Watanabe,K. Kikuchi,Angew. Chem. Int. Ed.,2011年12月,研究論文(学術雑誌)
  • In Vivo Fluorescence Imaging of Bone-Resorbing Osteoclasts,T. Kowada,J. Kikuta,A. Kubo,M. Ishii,H. Maeda,S. Mizukami,K. Kikuchi,J. Am. Chem. Soc.,2011年12月,研究論文(学術雑誌)
  • Switching Modulation for Protein Labeling with Activatable Fluorescent Probe,K.K. Sadhu,S. Mizumkami,Y. Hori,K. Kikuchi,ChemBioChem,2011年12月,研究論文(学術雑誌)
  • Multicolor Protein Labeling in Living Cells Using Mutant b-Lactamase-tag Technology,S. Watanabe,S. Mizukami,Y. Hori,K. Kikuchi,Bioconjugate Chem.,,2010年12月,研究論文(学術雑誌)
  • Turn-on Fluorescence Switch Involving Aggregation and Elimination Processes for b-Lactamase-Tag,K.K. Sadhu,S. Mizukami,S. Watanabe,K. Kikuchi,Chem. Commun.,,2010年12月,研究論文(学術雑誌)
  • Design, Synthesis and Biological Application of Chemical Probes for Bio-imaging,K. Kikuchi,Chem. Soc. Rev.,2010年12月,研究論文(学術雑誌)
  • Design, Synthesis and Biological Application of Fluortescent Sensor Molecules for Cellular Imaging,K. Kikuchi,Nano/micro Biotechnology,2010年12月,研究論文(学術雑誌)
  • Photocontrolled Compound Release System Using Caged Antimicrobial Peptide,S. Mizukami,M. Hosoda,T. Satake,S. Okada,Y. Hori,T. Furuta,K. Kikuchi,2010年05月,研究論文(学術雑誌)
  • Noncovalent-interaction-promoted ligation for protein labeling,Hori Y,Egashira Y,Kamiura R,Kikuchi K,ChemBioChem,,2010年03月,研究論文(学術雑誌)
  • Noncovalent-interaction-promoted ligation for protein labeling,Hori Y,Egashira Y,Kamiura R,Kikuchi K,2010年03月,研究論文(学術雑誌)
  • Application of Stimuli-responsive Polymer for Development of Novel MRI Probes,Satoshi Okada,Shin Mizukami,Kazuya Kikuchi,ChemBioChem,2010年03月,研究論文(学術雑誌)
  • 化学プローブのデザイン・合成によるタンパク質機能の可視化ツール,水上進,菊地和也,生化学,Vol. 82,No. 1,p. 21-29,2010年01月
  • Zinc is an Essential Trace Element for Spermatogenesis,S. Yamaguchi,C. Miura,F.T. Celino,T. Agusa,S. Tanabe,K. Kikuchi,T. Miura,Proc. Natl. Acad. Sci. U.S.A.,2009年12月,研究論文(学術雑誌)
  • Anion Sensor-Based Ratiometric Peptide Probe for Protein Kinase Activity,K. Kikuchi,S. Hashimoto,S. Mizukami,T. Nagano,Org. Lett.,,2009年12月,研究論文(学術雑誌)
  • Dual Functional Probe to Detect Protease Activity for Fluorescence Measurement and 19F MRI,S. Mizukami,R. Takikawa,F. Sugihara,M. Shirakawa,K. Kikuchi,Angew. Chem. Int. Ed.,,Vol. 48,No. 20,p. 3641-3,2009年12月,研究論文(学術雑誌)
  • Covalent Protein Labeling Based on Non-catalytic -Lactamase and a Designed FRET Substrate,S. Mizukami,S. Watanabe,Y. Hori,K. Kikuchi,J. Am. Chem. Soc.,,2009年12月,研究論文(学術雑誌)
  • Photoactive Yellow Protein-Based Protein Labeling System with Turn-on Fluorescence Intensity,Y. Hori,H. Ueno,S.Mizukami,K. Kikuchi,J. Am. Chem. Soc.,2009年12月,研究論文(学術雑誌)
  • Photoactive yellow protein-based protein labeling system with turn-on fluorescence intensity,Hori Y,Ueno H,Mizukami S,Kikuchi K,J. Am. Chem. Soc.,2009年11月,研究論文(学術雑誌)
  • Design and Synthesis of Coumarin-based Zn2+ Probes for Ratiometric Fluorescence Imaging,Shin Mizukami,Satoshi Okada,Satoshi Kimura,Kazuya Kikuchi,Inorg. Chem.,2009年07月,研究論文(学術雑誌)
  • Development of Ratiometric Fluorescent Probes for Phosphatases Using pKa-Switching Mechanism,Shin Mizukami,Shuji Watanabe,Kazuya Kikuchi,ChemBioChem,2009年06月,研究論文(学術雑誌)
  • in vivoイメージングを目指した可視化プローブ開発,菊地和也,水上進,ぶんせき,2009年04月
  • Covalent Protein Labeling Based on Noncatalytic beta-Lactamase and a Designed FRET Substrate,Shin Mizukami,Shuji Watanabe,Yuichiro Hori,Kazuya Kikuchi,J. Am. Chem. Soc.,2009年04月,研究論文(学術雑誌)
  • Dual-Function Probe to Detect Protease Activity for Fluorescence Measurement and 19F MRI,Shin Mizukami,Rika Takikawa,Fuminori Sugihara,Masahiro Shirakawa,Kazuya Kikuchi,Angew. Chem. Int. Ed.,Vol. 48,No. 20,p. 3641-3,2009年04月,研究論文(学術雑誌)
  • Lanthanide-based Protease Activity Sensors for Time-resolved Fluorescence Measurements,Shin Mizukami,Kazuhiro Tonai,Masahiro Kaneko,Kazuya Kikuchi,J. Am. Chem. Soc.,2008年10月,研究論文(学術雑誌)
  • Selective Photoinactivation of Protein Function through Environment-sensitive Switching of Singlet Oxygen Generation by Photosensitizer,T. Yogo,Y. Urano,A. Mizushima,H. Sunahara,T. Inoue,K. Hirose,M. Iino,K. Kikuchi,T. Nagano,Proc. Na t. Acad. Sci. U.S.A.,2008年04月,研究論文(学術雑誌)
  • A Gd3+-Based Magnetic Resonance Imaging Contrast Agent Sensitive to beta-Galactosidase Activity Utilizing a Receptor-Induced Magnetization Enhancement (RIME) Phenomenon,K. Hanaoka,K. Kikuchi,T. Terai,T. Komatsu,T. Nagano,Chem. Eur. J.,2008年03月,研究論文(学術雑誌)
  • Insights into Zn2+ Homeostasis in Neurons from Experimental and Modeling Studies,R.A. Colvin,A.L. Bush,I Volitakis,C.P. Fontaine,D. Thomas,K. Kikuchi,W.R.Holmes,Am. J. Physiol., Cell Physiol.,2008年03月,研究論文(学術雑誌)
  • Paramagnetic Relaxation-based 19F MRI Probe to Detect Protease Activity,Shin Mizukami,Rika Takikawa,Fuminori Sugihara,Yuichiro Hori,Hidehito Tochio,Markus Waelchli,Masahiro Shirakawa,Kazuya Kikuchi,J. Am. Chem. Soc.,Vol. 130,No. 3,p. 794-795,2008年01月,研究論文(学術雑誌)
  • A Time-resolved Long-lived Luminescence Imaging Method Employing Luminescent Lanthanide Probes with a New Microscopy System,K. Hanaoaka,K. Kikuchi,S. Kobayashi,T. Nagano,J. Am. Chem. Soc.,2007年09月,研究論文(学術雑誌)
  • Iron Hydroxide Nanoparticles Coated with Poly(ethylene glycol)-poly(aspartic acid) Block Copolymer as Novel Magnetic Resonance Contrast Agents for in Vivo Cancer Imaging,M. Kumagai,Y. Imai,T. Nakamura,Y. Yamasaki,M. Sekino,S. Ueno,K. Hanaoka,K. Kikuchi,Nagano,E. Kaneko,K. Shimokado,K. Kataoka,Coll. Surf. B-Bioint.,Vol. 56,No. 1-2,p. 174-81,2007年07月,研究論文(学術雑誌)
  • Design and Synthesis of an Enzyme Activity-Based Labeling Molecule with Fluorescence Spectral Change,T. Komatsu,K. Kikuchi,H. Takakusa,K. Hanaoka,T. Ueno,M. Kamiya,Y. Urano,T. Nagano,Vol. 128,No. 50,p. 15946-15947,2006年12月,研究論文(学術雑誌)
  • A Bridge between Chemistry and Biology,K. Kikuchi,H. Kakeya,Nature Chemical Biology,2006年10月,研究論文(学術雑誌)
  • Toward Bifunctional Antibody Catalysis,K. Kikuchi,R.B. Hannak,M.J. Guo,A.J. Kirby,D. Hilvert,Bioorg. Med. Chem.,2006年10月,研究論文(学術雑誌)
  • Fluorescence-based Zinc Ion Sensor for Zinc Ion Release from Pancreatic Cells,G. Crivat,K. Kikuchi,T. Nagano,T. Priel,M. Hershfinkel,I. Sekler,N. Rozenzweig,Z. Rosenzweig,Anal. Chem.,2006年10月,研究論文(学術雑誌)
  • Modulation of Luminescence Intensity of Lanthanide Complexes by Photoinduced Electron Transfer and its Application to a Long-Lived Protease Probe,T. Terai,K. Kikuchi,S. Iwasawa,T. Kawabe,Y. Hirata,Y. Urano,T. Nagano,J. Am. Chem. Soc.,2006年04月,研究論文(学術雑誌)
  • Inhibition of Presynaptic Activity by Zinc Released From Mossy Terminals During Tetanic Stimulation,A. Minami,N. Sakurada,S. Fuke,K. Kikuchi,T. Nagano,N. Oku,A. Takeda,J. Neurosci. Res.,2006年01月,研究論文(学術雑誌)
  • Evidence for pH Dependent Zn2+ Influx in K562 Erythroleukemia Cells: Studies Using ZnAF-2F Fluorescence and Zn-65(2+) Uptake,R.A.Colvin,P. Fontaine,D. Thomas,T. Hirano,T. Nagano,K. Kikuchi,Arch. Biochem. Biophys,2005年08月,研究論文(学術雑誌)
  • Inhibition of Autotaxin by Lysophosphatidic Acid and Sphingosine-1-phosphate,L.A. van Meeteren,P. Ruurs,E. Christodoulou,J.W. Goding,H. Takakusa,K. Kikuchi,A. Perrakis,T. Nagano,W.H. Moolenaar,J. Biol. Chem.,2005年08月,研究論文(学術雑誌)
  • Selective zinc sensor molecules with various affinities for Zn2+, revealing dynamics andregional distribution of synaptically released Zn2+ in hippocampal slices,Komatsu,K. Kikuchi,Y. Urano,H. Kojima,T. Nagano,J. Am. Chem. Soc.,2005年07月,研究論文(学術雑誌)
  • Highly Sensitive Near-infrared Fluorescence Probes for Nitric Oxide and Their Application to Isolated Organs,E. Sasaki,H. Kojima,H. Nishimatsu,Y. Urano,K. Kikuchi,Y. Hirata,T. Nagano,J. Am. Chem. Soc.,2005年06月,研究論文(学術雑誌)
  • Design and Synthesis of Zinc-Selective Chelators for Extracellular Applications,E. Kawabata,K. Kikuchi,Y. Urano,H. Kojima,A. Odani,T. Nagano,J. Am. Chem. Soc.,2005年01月,研究論文(学術雑誌)
  • Role of Zinc Ion on the Initiation of Sperm Motility in Starfish,M. Morisawa,K. Komatsu,T. Togo,S. Morisawa,K. Kikuchi,T. Nagano,Zoo. Sci.,,2004年12月,研究論文(学術雑誌)
  • A Novel Fluorescent Probe for Zinc Ion Based on Boron Dipyrromethene (BODIPY) Chromophore,H. Koutaka,J. Kosuge,N. Fukasaku,T. Hirano,K. Kikuchi,Y. Urano,H. Kojima,T.Nagano,Chem. Pharm. Bull.,2004年12月,研究論文(学術雑誌)
  • Rational Principles for Modulating Fluorescence Properties of Fluorescein,T. Ueno,Y. Urano,K. Setsukinai,H. Takakusa,H. Kojima,K. Kikuchi,K. Ohkubo,S.Fukuzumi,T. Nagano,J. Am. Chem. Soc.,2004年12月,研究論文(学術雑誌)
  • Rational Design of Novel Photoinduced Electron Transfer Type Fluorescent Probes for Sodium Cation,S. Kenmoku,Y. Urano,K. Kanda,H. Kojima,K. Kikuchi,T. Nagano,Tetrahedron,,2004年12月,研究論文(学術雑誌)
  • Highly Sensitive Fluorescence Probes for Nitric Oxide Based on Boron Dipyrromethene Chromophore -Rational Design of Potentially Useful BioimagingFluorescence Probe-,Y. Gabe,Y. Urano,K. Kikuchi,H. Kojima,T. Nagano,J. Am. Chem. Soc.,2004年12月,研究論文(学術雑誌)
  • Distinct Glutamate Receptors Govern Differential Levels of Nitric Oxide Production in a Layer-specific Manner in the Rat Cerebellar Cortex,D. Okada,C.C. Yap,H. Kojima,K. Kikuchi,T. Nagano,Neuroscience,2004年12月,研究論文(学術雑誌)
  • Small Molecule Based FRET Sensors Which Enable Ratiometric Imaging of Living Cells,K. Kikuchi,Bioimages,2004年12月,研究論文(学術雑誌)
  • Modification of Intracellular Ca2+ Dynamics by Laser Inactivation of Inositol 1,4,5-Trisphosphate Receptor Using Membrane-permeant Probes,T. Yogo,K. Kikuchi,K. Hirose,M. Iino,T. Nagano,Chemistry & Biology,2004年10月,研究論文(学術雑誌)
  • Development of a Zinc Ion-selective Luminescent Lanthanide Chemosensor forBiological Applications,K. Hanaoka,K. Kikuchi,H. Kojima,Y. Urano,T. Nagano,J. Am. Chem. Soc.,2004年09月,研究論文(学術雑誌)
  • Nonspecific Medium Effects versus Specific Group Positioning in the Antibody andAlbumin Catalysis of the Base-Promoted Ring-Opening Reactions of Benzisoxazole,Y. Hu,K.N. Houk,K. Kikuchi,K. Hotta,D. Hilvert,J. Am. Chem. Soc.,2004年08月,研究論文(学術雑誌)
  • Highly Sensitive Fluorescence Probes for Nitric Oxide Based on Boron Dipyrromethene Chromophore -Rational Design of Potentially Useful Bioimaging Fluorescence Probe-,Y. Gabe,Y. Urano,K. Kikuchi,H. Kojima,T. Nagano,J. Am. Chem. Soc.,2004年06月,研究論文(学術雑誌)
  • Zinc Sensing for Cellular Applications,K. Kikuchi,K. Komatsu,T. Nagano,Curr. Opi. Chem. Biol,2004年05月
  • Distinct Glutamate Receptors Govern DifferentialLevels of Nitric Oxide Production in a Layer-specific Manner in the Rat Cerebellar Cortex,D. Okada,C.C. Yap,H. Kojima,K. Kikuchi,T. Nagano,Neuroscience,2004年05月,研究論文(学術雑誌)
  • Recent Advances in Design of Small Molecule Based FRET Sensors for Cell Biology,K. Kikuchi,H. Takakusa,T. Nagano,Trends Anal. Chem,2004年04月
  • Development of Selective, Visible Light-excitable, Fluorescent Magnesium Probes with a Novel Fluorescence Switching Mechanism,T. Shoda,K. Kikuchi,H. Kojima,Y. Urano,H. Komatsu,K. Suzuki,T. Nagano,The Analyst,,2003年12月,研究論文(学術雑誌)
  • A Novel Design Method of Ratiometric Fluorescent Probes Based on Fluorescence Resonance Energy Transfer Switching by Spectral Overlap Integral,H. Takakusa,K. Kikuchi,Y. Urano,H. Kojima,T. Nagano,Chem. Eur. J.,,2003年12月,研究論文(学術雑誌)
  • Spatiotemporal Laser Inactivation of Inositol 1,4,5-Trisphosphate Receptors Using Synthetic Small-molecule Probes,T. Inoue,K. Kikuchi,K. Hirose,M. Iino,T. Nagano,Chemistry & Biology,,2003年12月,研究論文(学術雑誌)
  • Selective Detection of Zinc Ions with Novel Luminescent Lanthanide Probes,K. Hanaoka,K. Kikuchi,H. Kojima,Y. Urano,T. Nagano,Angew. Chem. Int. Ed.,2003年05月,研究論文(学術雑誌)
  • Hydrophobic Modifications at 1-Phosphate of Inositol 1,4,5-Trisphosphate Analogues Enhance Receptor Binding,W. Nakanishi,K. Kikuchi,T. Inoue,K. Hirose,M. Iino,T. Nagano,Bioorg. Med. Chem. Lett.,2002年12月,研究論文(学術雑誌)
  • Orthogonality of Calcium Concentration and Ability of 4,5-Diaminofluorescein (DAF-2) to Detect NO,N. Suzuki,H. Kojima,Y. Urano,K. Kikuchi,Y. Hirata,T. Nagano,J. Biol. Chem.,,2002年12月,研究論文(学術雑誌)
  • Design and Synthesis of a Novel Magnetic Resonance Imaging Contrast Agent for Selective Sensing of Zinc Ion,K. Hanaoka,K. Kikuchi,Y. Urano,M. Narazaki,T. Yokawa,S. Sakamoto,K. Yamaguchi,T. Nagano,Chemistry & Biology,2002年12月,研究論文(学術雑誌)
  • A Novel, Cell-Permeable, Fluorescent Probe for Ratiometric Imaging of Zinc Io,S. Maruyama,K. Kikuchi,T. Hirano,Y. Urano,T. Nagano,J. Am. Chem. Soc.,2002年11月,研究論文(学術雑誌)
  • Mossy Fiber Zn2+ Spillover Modulates Heterosynaptic N-methyl-D-aspartate Receptor Activity in Hippocampel CA3 Circuits,S. Ueno,M. Tsukamoto,T. Hirano,K. Kikuchi,M. K. Yamada,N. Nishiyama,T. Nagano,N.Matsuki,Y. Ikegaya,J. Cell Biology,,2002年07月,研究論文(学術雑誌)
  • Improved Fluorescent Probes for Zinc, ZnAFs, Suitable for Biological Applications,T. Hirano,K. Kikuchi,Y. Urano,T. Nagano,J. Am. Chem. Soc.,2002年06月,研究論文(学術雑誌)
  • A Fluorescent Anion Sensor That Works in Neutral Aqueous Solution for Bioanalytical Application,S. Mizukami,T. Nagano,Y. Urano,A. Odani,K. Kikuchi,J. Am. Chem. Soc.,2002年05月,研究論文(学術雑誌)
  • Design and Synthesis of an Enzyme-Cleavable Sensor Molecule for Phosphodiesterase Activity Based on Fluorescence Resonance Energy Transfer,H. Takakusa,K. Kikuchi,Y. Urano,S. Sakamoto,K. Yamaguchi,T. Nagano,J. Am. Chem. Soc.,2002年03月,研究論文(学術雑誌)
  • Selective Inhibition of Human Inducible Nitric Oxide Synthase by S-Alkyl-L-isothiocitrulline -containing Dipeptides,J.M. Park,T. Higuchi,K. Kikuchi,Y. Urano,H. Hori,T. Nishino,J. Aoki,K. Inoue,T. Nagano,Br. J. Pharmacol.,,2001年12月,研究論文(学術雑誌)
  • Rational Design of Fluorescein-based Fluorescence Probes. -Mechanism-based Design of a Maximum Fluorescence Probe for Singlet Oxygen-,K. Tanaka,T. Miura,N. Umezawa,Y. Urano,K. Kikuchi,T. Higuchi,T. Nagano,J. Am. Chem. Soc.,,2001年12月,研究論文(学術雑誌)
  • Visualization of Oxygen Concentration-dependent Production of Nitric Oxide in Rat Hippocampal Slices during Aglycemia,H. Kojima,M. Hirata,Y. Kudo,K. Kikuchi,T. Nagano,J. Neurochem.,2001年12月,研究論文(学術雑誌)
  • Bioimaging of Nitric Oxide with Fluorescent Indicators Based on Rhodamine Chromophore,H. Kojima,M. Hirotani,N. Nakatsubo,K. Kikuchi,Y. Urano,T. Higuchi,Y. Hirata,T. Nagano,Anal. Chem.,,2001年12月,研究論文(学術雑誌)
  • Selective Sensing of Zinc Ion with A Nobel Magnetic Resonance Imaging Contrast Agent,K. Hanaoka,K. Kikuchi,Y. Urano,T. Nagano,J. Chem. Soc., Perk. Trans.,2001年12月,研究論文(学術雑誌)
  • Intramolecular Fluorescence Resonance Energy Transfer System with Coumarin Donor Included in beta-Cyclodextrin,H. Takakusa,K. Kikuchi,Y. Urano,T. Higuchi,T. Nagano,Anal. Chem.,,2001年12月,研究論文(学術雑誌)
  • Small Molecule-based Laser Inactivation of Inositol 1,4,5-Triphosphate Receptor,T. Inoue,K. Kikuchi,K. Hirose,M. Iino,T. Nagano,Chemistry & Biology,,2001年12月,研究論文(学術雑誌)
  • First Synthetic NO-heme-thiolate Complex Relevant to Nitric Oxide Synthase and Cytochrome P450nor,N. Suzuki,T. Higuchi,Y. Urano,K. Kikuchi,T. Uchida,M. Mukai,T. Kitagawa,T. Nagano,J. Am. Chem. Soc.,,2000年12月,研究論文(学術雑誌)
  • Fluorescence Switching by O-Dearylation of 7-Aryloxycoumarins.-Development of Novel Fluorescence Probes to Detect Reactive Oxygen Species with High Selectivity,K. Setsukinai,Y. Urano,K. Kikuchi,T. Higuchi,T. Nagano,J. Chem. Soc. Perk. Trans.,2000年12月,研究論文(学術雑誌)
  • A New Thioether-ligated Iron Porphyrin as a Model of a Protonated Form of P450 Active Site,T. Dokoh,N. Suzuki,T. Higuchi,Y. Urano,K. Kikuchi,T. Nagano,J. Inorg. Biochem.,,2000年12月,研究論文(学術雑誌)
  • Superoxide Dismutase Activity of Iron(II) TPEN Complex and Its Derivatives,M. Tamura,Y. Urano,K. Kikuchi,T. Higuchi,M. Hirobe,T. Nagano,Chem. Pharm. Bull.,,2000年12月,研究論文(学術雑誌)
  • Synthesis and Superoxide Dismutase Activity of Novel Iron Complexes,M. Tamura,Y. Urano,K. Kikuchi,T. Higuchi,M. Hirobe,T. Nagano,J. Organomet. Chem.,,2000年12月,研究論文(学術雑誌)
  • Remarkable Axial Thiolate Ligand Effects on the Oxidation of Hydrocarbons by Active Intermediate of Iron Porphyrin and Cytochrome P450,T. Ohno,N. Suzuki,T. Dokoh,Y. Urano,K. Kikuchi,M. Hirobe,T. Higuchi,T.Nagano,J. Inorg. Biochem.,,2000年12月,研究論文(学術雑誌)
  • Effects of Tetrahydrobiopterin on Endothelial Dysfunction in Rats with Ischemic Acute Renal Failure,M. Kakoki,Y. Hirata,H. Hayakawa,E. Suzuki,D. Nagata,A. Tojo,H. Nishimatsu,K. Kikuchi,T. Nagano,M. Omata,J. Am. Soc. Nephrol.,,2000年12月,研究論文(学術雑誌)
  • Fluorescent Indicators for Nitric Oxide Based on Rhodamine Chromophore,H. Kojima,M. Hirotani,Y. Urano,K. Kikuchi,T. Higuchi,T. Nagano,Tetrahedron Lett.,,2000年12月,研究論文(学術雑誌)
  • Characterization of Proton-Transfer Catalysis by Serum Albumins,F. Hollfelder,A. J. Kirby,D. S. Tawfik,K. Kikuchi,D. Hilvert,J. Am. Chem. Soc.,,2000年12月,研究論文(学術雑誌)
  • Decarboxylation of 3-Carboxybenzisoxazoles by Hydrophobic Antibody Binding Pockets,K. Hotta,K. Kikuchi,D. Hilvert,Helv. Chem. Acta,,2000年12月,研究論文(学術雑誌)
  • Development of Time-resolved Fluorometric Detection System Using Diffusion-enhanced Energy Transfer,M. Koresawa,K. Kikuchi,S. Mizukami,H. Kojima,Y. Urano,T. Higuchi,T. Nagano,Anal. Chem.,,2000年12月,研究論文(学術雑誌)
  • Novel Zinc Fluorescent Probes Excitable with Visible Light for Biological Applications,T. Hirano,K. Kikuchi,Y. Urano,T. Higuchi,T. Nagano,Angew. Chem. Int. Ed.,2000年12月,研究論文(学術雑誌)
  • Design and Synthesis of Intramolecular Resonance Energy Transfer Probes for Use in Ratiometric Measurements in Aqueous Solution,Y. Kawanishi,K. Kikuchi,H. Takakusa,S. Mizukami,Y. Urano,T. Higuchi,T.Nagano,Angew. Chem. Int. Ed.,,2000年12月,研究論文(学術雑誌)
  • Highly Zinc-selective Fluorescent Sensor Molecules Suitable for Biological Applications,T. Hirano,K. Kikuchi,Y. Urano,T. Higuchi,T. Nagano,J. Am. Chem. Soc.,2000年12月,研究論文(学術雑誌)
  • Novel Iron Porphyrin-alkanethiolate Complex with Intramolecular NH...S Hydrogen Bond: Synthesis, Spectroscopy and Reactivity,N. Suzuki,T. Higuchi,Y. Urano,K. Kikuchi,H. Uekusa,Y. Ohashi,T. Uchida,T.Kitagawa,T. Nagano,J. Am. Chem. Soc.,,1999年12月,研究論文(学術雑誌)
  • Dipeptides Containing L-Arginine Analogs: New Isozyme-selective Inhibitors of Nitric Oxide Synthase,N. Kobayashi,T. Higuchi,Y. Urano,K. Kikuchi,M. Hirobe,T. Nagano,Biol. Pharm. Bull.,,1999年12月,研究論文(学術雑誌)
  • Effects of Vasodilatory b-Adrenoceptor Antagonists on Endothelium-Derived Nitric Oxide Release in Rat Kidney,M. Kakoki,Y. Hirata,H. Hayakawa,H. Nishimatsu,Y. Suzuki,D. Nagata,E. Suzuki,K. Kikuchi,T. Nagano,M. Omata,Hypertension,,1999年12月,研究論文(学術雑誌)
  • Role of Nitric Oxide-cGMP Pathway in Adrenomedullin-induced Vasodilation in Rat,H. Hayakawa,Y. Hirata,M. Kakoki,Y. Suzuki,H. Nishimatsu,D. Nagata,E. Suzuki,K. Kikuchi,T. Nagano,K. Kangawa,H. Matsuo,T. Sugimoto,M. Omata,Hypertension,,1999年12月,研究論文(学術雑誌)
  • Effects of Hypertension, Diabetes Mellitus and Hypercholesterolemia on Endothelin Type B Receptor-mediated Nitric Oxide Release from Rat Kidney,M. Kakoki,Y. Hirata,H. Hayakawa,A. Tojo,D. Nagata,E. Suzuki,K. Kimura,A. Goto,K. Kikuchi,T. Nagano,M. Omata,Circulation,,1999年12月,研究論文(学術雑誌)
  • Fluorescent Indicators for Imaging Nitric Oxide Production,H. Kojima,Y. Urano,K. Kikuchi,T. Higuchi,T. Nagano,Angew. Chem. Int. Ed.,,1999年12月,研究論文(学術雑誌)
  • Novel Fluorescent Probes for Singlet Oxygen,N. Umezawa,K. Tanaka,Y. Urano,K. Kikuchi,T. Higuchi,T. Nagano,Angew. Chem. Int. Ed.,,1999年12月,研究論文(学術雑誌)
  • Synthesis and Evaluation of 1-Position-modified Inositol 1,4,5-Trisphosphate Analogs,T. Inoue,K. Kikuchi,K. Hirose,M. Iino,T. Nagano,Bioorg. Med. Chem. Lett.,,1999年12月,研究論文(学術雑誌)
  • Imaging of Caspase-3 Activation in HeLa Cells Stimulated with Etoposide Using a Novel Fluorescent Probe,S. Mizukami,K. Kikuchi,T. Higuchi,Y. Urano,T. Mashima,T. Tsuruo,T. Nagano,FEBS Lett.,,1999年12月,研究論文(学術雑誌)
  • Real Time Measurement of Nitric Oxide Release from Cultured Endothelial Cells,H. Kurumatani,K. Kikuchi,T. Nagano,M. Hirobe,J. Yamazaki,T. Nagao,Biol. Pharm. Bull.,,1998年12月,研究論文(学術雑誌)
  • Selective Deoxygenation of Heteroaromatic N-Oxides with Olefins Catalyzed by Ruthenium Porphyrin,H. Nakagawa,T. Higuchi,K. Kikuchi,Y. Urano,T. Nagano,Chem. Pharm. Bull.,,1998年12月,研究論文(学術雑誌)
  • Improved Nitric Oxide Detection Method Using 2,3-Diaminonaphthalene and Its Application to Evaluation of Novel Nitric Oxide Synthase Inhibitors,N. Nakatsubo,H. Kojima,K. Sakurai,K. Kikuchi,H. Nagoshi,Y. Hirata,T. Akaike,H. Maeda,Y. Urano,T. Higuchi,T. Nagano,Biol. Phram. Bull.,,1998年12月,研究論文(学術雑誌)
  • Development of a Fluorescent Indicator for Bioimaging of Nitric Oxide Based on the Fluorescein Chromophore,H. Kojima,K. Sakurai,K. Kikuchi,S. Kawahara,Y. Kirino,H. Nagoshi,Y. Hirata,T. Nagano,Chem. Pharm. Bull.,,1998年12月,研究論文(学術雑誌)
  • Direct Evidence of NO Production in Rat Hippocampus and Cortex Using a New Fluorescent Indicator: DAF-2 DA,H. Kojima,N. Nakatsubo,K. Kikuchi,Y. Urano,T. Higuchi,J. Tanaka,Y. Kudo,T. Nagano,Neuroreport,,1998年12月,研究論文(学術雑誌)
  • Direct Evidence of Nitric Oxide Production from Bovine Aortic Endothelial Cells Using New Fluorescence Indicators: Diaminofluoresceins,N. Nakatsubo,H. Kojima,K. Kikuchi,H. Nagoshi,Y. Hirata,D. Maeda,Y. Imai,T. Irimura,T. Nagano,FEBS Lett.,,1998年12月,研究論文(学術雑誌)
  • Detection and Imaging of Nitric Oxide with Novel Fluorescent Indicators,H. Kojima,N. Nakatsubo,K. Kikuchi,S. Kawahara,Y. Kirino,H. Nagoshi,Y. Hirata,T. Nagano,Anal. Chem.,,1998年12月,研究論文(学術雑誌)
  • Development of a Fluorescent Indicator for the Bioimaging of Nitric Oxide,H. Kojima,K. Sakurai,K. Kikuchi,S. Kawahara,Y. Kirino,H. Nagoshi,Y. Hirata,T. Akaike,H. Maeda,T. Nagano,Biol. Pharm. Bull.,,1997年12月,研究論文(学術雑誌)
  • Real-time Measurement of Nitric Oxide Production in Rat Brain by the Combination of Luminol-H2O2 Chemiluminescence and Microdialysis,H. Kojima,K. Kikuchi,M. Hirobe,T. Nagano,Neurosci. Lett.,,1997年12月,研究論文(学術雑誌)
  • Receptor Subtype for Vasopressin-induced Release of Nitric Oxide from Rat Kidney,Y. Hirata,H. Hayakawa,M. Kakoki,A. Tojo,E. Suzuki,D. Nagata,K. Kimura,A. Goto,K. Kikuchi,T. Nagano,M. Hirobe,M. Omata,Hypertension,,1997年12月,研究論文(学術雑誌)
  • Nitric Oxide Release from Kidneys of Hypertensive Rats Treated with Imidapril,Y. Hirata,H. Hayakawa,M. Kakoki,A. Tojo,K. Kimura,A. Goto,K. Kikuchi,T. Nagano,M. Hirobe,M. Omata,Hypertension,1996年12月,研究論文(学術雑誌)
  • Nobel Detection Method of Nitric Oxide Using Horseradish Peroxidase,K. Kikuchi,T. Nagano,M. Hirobe,Biol. Pharm. Bull.,,1996年12月,研究論文(学術雑誌)
  • Antibody Catalysis Via Strategic Use of Haptenic Charge,K. Kikuchi,D. Hilvert,Acta Chem. Scand.,,1996年12月,研究論文(学術雑誌)
  • Albumin-catalyzed Proton Transfer,K. Kikuchi,S. N. Thor,D. Hilvert,J. Am. Chem. Soc.,,1996年12月,研究論文(学術雑誌)
  • Endothelium-derived Relaxing Factors in the Kidney of Spontaneously Hypertensive Rats,H. Hayakawa,Y. Hirata,E. Suzuki,M. Kakoki,K. Kikuchi,T. Nagano,M. Hirobe,M. Omata,Life Sci.,,1995年12月,研究論文(学術雑誌)
  • Direct Measurement of Endothelium Derived Nitric Oxide Release by Stimulation of Endothelin Receptors in Rat Kidney and Its Alteration in Salts-induced Hypertension,Y. Hirata,H. Hayakawa,E. Suzuki,K. Kimura,K. Kikuchi,T. Nagano,M. Hirobe,M. Omata,Circulation,1995年12月,研究論文(学術雑誌)
  • Long-term Administration of L-Arginine Improves Nitric Oxide Release from Kidney in DOCA Salt Hypertensive Rats,H. Hayakawa,Y. Hirata,E. Suzuki,K. Kimura,K. Kikuchi,T. Nagano,M. Hirobe,M. Omata,Hypertension,1994年12月,研究論文(学術雑誌)
  • Mechanisms for Altered Endothelium-dependent Vasodilation in Isolated Kidneys from SHR, DOCA-salt Hypertensive Rat and Dahl Salt-sensitive Rats,H. Hayakawa,Y. Hirata,E. Suzuki,T. Sugimoto,H. Matsuoka,K. Kikuchi,T. Nagano,M. Hirobe,T. Sugimoto,Am. J. Physiol.,,1993年12月,研究論文(学術雑誌)
  • Detection of Nitric Oxide Production from a Perfused Organ by a Luminol-H2O2 System,K. Kikuchi,T. Nagano,H. Hayakawa,Y. Hirata,M. Hirobe,Anal. Chem.,,1993年12月,研究論文(学術雑誌)
  • Real Time Measurement of Nitric Oxide Produced Ex Vivo by Luminol-H2O2 Chemiluminescence Method,K. Kikuchi,T. Nagano,H. Hayakawa,Y. Hirata,M. Hirobe,J. Biol. Chem.,,1993年12月,研究論文(学術雑誌)
  • New Method of Detecting Nitric Oxide Production,K. Kikuchi,H. Hayakawa,T. Nagano,Y. Hirata,T. Sugimoto,M. Hirobe,Chem. Pharm. Bull.,,1992年12月,研究論文(学術雑誌)
  • Metabolism and Penetration through Blood-brain-barrier of Parkinsonism-related Compounds -1,2,3,4-Tetrahydroisoquinoline and 1-Methyl-1,2,3,4-tetrahydroisoquinoline-,K. Kikuchi,Y. Nagatsu,Y. Makino,T. Mashino,S. Ohta,M. Hirobe,Drug Met. Disp.,,1991年12月,研究論文(学術雑誌)

MISC

  • ヒストン修飾酵素の活性を検出する蛍光プローブの開発と応用,堀 雄一郎,菊地 和也,大阪大学低温センターだより,大阪大学低温センター,Vol. 158,p. 9-13,2012年04月
  • 合成蛍光プローブと発現タンパク質を用いた新規タンパク質ラベル化システム,堀 雄一郎,菊地 和也,生化學,日本生化学会,Vol. 83,No. 2,p. 135-139,2011年02月25日

著書

  • 教科書・概説・概論,発光イメージング実験ガイド「機能性セレンテラジンを用いた発光検出」,蓑島維文,菊地和也,羊土社,ISBN:4758122407,2019年09月
  • 学術書,Chemical Tools for Elucidation of Epigenetic Mechanisms,M. Minoshima,K. Kikuchi,Inperial College Press,ISBN:9781783269600,2016年09月
  • 学術書,ケミカルバイオロジー,長野哲雄,長田裕之,菊地和也,上杉志成,共立出版,2008年06月

特許・実用新案・意匠

  • 非線形発光分子,藤田克昌,水上進,菊地和也,河田聡,河野省悟,特願2009-152138,出願日:2009年06月
  • 非線形光学材料、光記録材料、光記録方法、感光性材料、フォトリソグラフィー法、光重合開始剤、及び光増感剤,藤田克昌,小林実,菊地和也,水上進,河田聡,河野省悟,PCT/JP2009/051373,出願日:2009年01月
  • タンパク質を蛍光標識する方法,菊地和也,水上進,渡辺修司,山本拓,特願2008-273182,特願2008-273182,出願日:2008年10月
  • MRI用プローブ,菊地和也,水上進,滝川利佳,白川昌宏,特願2007-273956,特願2007-273956,出願日:2007年10月
  • クマリン誘導体およびそれを含む蛍光プローブ,菊地和也,水上進,木村聡志,特願2007-059057,特願2007-059057,出願日:2007年03月
  • ホスホクマリン誘導体およびそれを含む蛍光プローブ,菊地和也,水上進,渡辺修司,特願2007-059058,特願2007-059058,出願日:2007年03月
  • アニオン検出用蛍光センサー,菊地 和也,水上 進,長野 哲雄,特開2003-254909,出願日:2003年03月
  • 亜鉛蛍光プローブ(Zn2+検出)(低親和性),菊地 和也,平野 智也,小松 兼介,長野 哲雄,特開2004-315501,出願日:2003年03月
  • 蛍光性ランタニド錯体,菊地 和也,岩澤 伸哉,長野 哲雄,特願2003-045786,出願日:2003年02月

受賞

  • 2015年度バイオインダストリー協会賞,菊地和也,(財)バイオインダストリー協会,2015年10月
  • 第6回日本学術振興会賞,菊地和也,日本学術振興会,2010年03月
  • 日本IBM科学賞,菊地和也,日本アイ・ビー・エム株式会社,2008年11月
  • Chemical society Reviews, Emerging investigator Award,Kazuya Kikuchi,Royal Society of Chemistry, United Kingdom,2008年05月
  • 富山県ひとづくり財団 平成14年度とやま賞,菊地和也,富山県ひとづくり財団,2002年05月
  • 日本薬学会 平成14年度奨励賞,菊地和也,日本薬学会,2002年03月
  • 日本化学会生体機能関連化学部会 部会講演賞,菊地和也,日本化学会生体機能関連化学部会,2001年09月

報道

  • 骨壊す細胞 じっくり観察」「阪大チーム 骨粗鬆薬に応用も」,朝日新聞,2016年06月