EN

基本情報

研究

社会活動

その他の活動

山本 雅裕

Yamamoto Masahiro

微生物病研究所,教授

myamamoto biken.osaka-u.ac.jp

keyword トキソプラズマ,病原体PLAMP,寄生虫免疫学,セルオートノマス免疫系

学歴

  • 2003年04月 ~ 2006年03月,大阪大学,大学院医学系研究科,博士課程
  • 2001年04月 ~ 2003年03月,大阪大学,大学院医学系研究科,医科学修士課程
  • 1999年04月 ~ 2001年03月,東京大学,理学部,生物学科
  • 1997年04月 ~ 1999年03月,東京大学,教養学部,理科一類

経歴

  • 2018年12月 ~ 継続中,大阪大学,栄誉教授
  • 2013年07月 ~ 継続中,大阪大学,微生物病研究所,教授
  • 2012年01月 ~ 2013年06月,大阪大学,微生物病研究所,独立准教授
  • 2010年05月 ~ 2011年12月,大阪大学,大学院医学系研究科,准教授
  • 2007年04月 ~ 2010年04月,大阪大学,大学院医学系研究科,助教
  • 2006年08月 ~ 2007年03月,大阪大学,大学院医学系研究科,助手

研究内容・専門分野

  • ライフサイエンス,実験動物学,ゲノム編集による分子遺伝学
  • ライフサイエンス,寄生虫学,トキソプラズマの寄生虫免疫学
  • ライフサイエンス,獣医学,家畜の感染免疫学

所属学会

  • 日本寄生虫学会
  • 日本免疫学会

論文

  • Plasmodium UIS3 avoids host cell-autonomous exclusion that requires GABARAPs but not LC3 and autophagy,Ariel Pradipta,Hironori Bando,Ji Su Ma,Shun Tanaka,Miwa Sasai,Masahiro Yamamoto,Parasitology International,Vol. 83,2021年08月,研究論文(学術雑誌)
  • Uncovering a novel role of PLCβ4 in selectively mediating TCR signaling in CD8+ but not CD4+ T cells.,Miwa Sasai,Ji Su Ma,Masaaki Okamoto,Kohei Nishino,Hikaru Nagaoka,Eizo Takashima,Ariel Pradipta,Youngae Lee,Hidetaka Kosako,Pann-Ghill Suh,Masahiro Yamamoto,The Journal of experimental medicine,Vol. 218,No. 7,2021年07月05日,研究論文(学術雑誌)
  • Cell-autonomous Toxoplasma killing program requires Irgm2 but not its microbe vacuolar localization.,Ariel Pradipta,Miwa Sasai,Kou Motani,Ji Su Ma,Youngae Lee,Hidetaka Kosako,Masahiro Yamamoto,Life science alliance,Vol. 4,No. 7,2021年07月,研究論文(学術雑誌)
  • Role of Gate-16 and Gabarap in Prevention of Caspase-11-Dependent Excess Inflammation and Lethal Endotoxic Shock,Naoya Sakaguchi,Miwa Sasai,Hironori Bando,Youngae Lee,Ariel Pradipta,Ji Su Ma,Masahiro Yamamoto,Frontiers in Immunology,Vol. 11,p. 561948-561948,2020年09月15日,研究論文(学術雑誌)
  • T cell-derived interferon-γ is required for host defense to Toxoplasma gondii.,Saishi Nishiyama,Ariel Pradipta,Ji Su Ma,Miwa Sasai,Masahiro Yamamoto,Parasitology international,Vol. 75,p. 102049-102049,2020年04月,研究論文(学術雑誌)
  • Decision by injection without infection.,Miwa Sasai,Masahiro Yamamoto,The Journal of experimental medicine,Vol. 217,No. 3,2020年03月02日,研究論文(学術雑誌)
  • Initial phospholipid-dependent Irgb6 targeting to Toxoplasma gondii vacuoles mediates host defense.,Youngae Lee,Hiroshi Yamada,Ariel Pradipta,Ji Su Ma,Masaaki Okamoto,Hikaru Nagaoka,Eizo Takashima,Daron M Standley,Miwa Sasai,Kohji Takei,Masahiro Yamamoto,Life science alliance,Vol. 3,No. 1,2020年01月,研究論文(学術雑誌)
  • CXCR4 regulates Plasmodium development in mouse and human hepatocytes,Hironori Bando,Ariel Pradipta,Shiroh Iwanaga,Toru Okamoto,Daisuke Okuzaki,Shun Tanaka,Joel Vega-Rodríguez,Youngae Lee,Ji Su Ma,Naoya Sakaguchi,Akira Soga,Shinya Fukumoto,Miwa Sasai,Yoshiharu Matsuura,Masao Yuda,Marcelo Jacobs-Lorena,Masahiro Yamamoto,Journal of Experimental Medicine,Vol. 216,No. 8,p. 1733-1748,2019年08月01日,研究論文(学術雑誌)
  • Toxoplasma Effector GRA15-Dependent Suppression of IFN-γ-Induced Antiparasitic Response in Human Neurons.,Hironori Bando,Youngae Lee,Naoya Sakaguchi,Ariel Pradipta,Ryoma Sakamoto,Shun Tanaka,Ji Su Ma,Miwa Sasai,Masahiro Yamamoto,Frontiers in cellular and infection microbiology,Vol. 9,No. MAY,p. 140-140,2019年,研究論文(学術雑誌)
  • Inducible Nitric Oxide Synthase Is a Key Host Factor for Toxoplasma GRA15-Dependent Disruption of the Gamma Interferon-Induced Antiparasitic Human Response.,Hironori Bando,Youngae Lee,Naoya Sakaguchi,Ariel Pradipta,Ji Su Ma,Shun Tanaka,Yihong Cai,Jianfa Liu,Jilong Shen,Yoshifumi Nishikawa,Miwa Sasai,Masahiro Yamamoto,mBio,Vol. 9,No. 5,2018年10月09日,研究論文(学術雑誌)
  • Toxoplasma Effector TgIST Targets Host IDO1 to Antagonize the IFN-γ-Induced Anti-parasitic Response in Human Cells.,Hironori Bando,Naoya Sakaguchi,Youngae Lee,Ariel Pradipta,Ji Su Ma,Shun Tanaka,De-Hua Lai,Jianfa Liu,Zhao-Rong Lun,Yoshifumi Nishikawa,Miwa Sasai,Masahiro Yamamoto,Frontiers in immunology,Vol. 9,No. SEP,p. 2073-2073,2018年,研究論文(学術雑誌)
  • Essential role for GABARAP autophagy proteins in interferon-inducible GTPase-mediated host defense.,Miwa Sasai,Naoya Sakaguchi,Ji Su Ma,Shuhei Nakamura,Tsuyoshi Kawabata,Hironori Bando,Youngae Lee,Tatsuya Saitoh,Shizuo Akira,Akiko Iwasaki,Daron M Standley,Tamotsu Yoshimori,Masahiro Yamamoto,Nature immunology,Vol. 18,No. 8,p. 899-910,2017年08月,研究論文(学術雑誌)
  • p62 Plays a Specific Role in Interferon-γ-Induced Presentation of a Toxoplasma Vacuolar Antigen.,Youngae Lee,Miwa Sasai,Ji Su Ma,Naoya Sakaguchi,Jun Ohshima,Hironori Bando,Tatsuya Saitoh,Shizuo Akira,Masahiro Yamamoto,Cell reports,Vol. 13,No. 2,p. 223-33,2015年10月13日,研究論文(学術雑誌)
  • RabGDIα is a negative regulator of interferon-γ-inducible GTPase-dependent cell-autonomous immunity to Toxoplasma gondii.,Jun Ohshima,Miwa Sasai,Jianfa Liu,Kazuo Yamashita,Ji Su Ma,Youngae Lee,Hironori Bando,Jonathan C Howard,Shigeyuki Ebisu,Mikako Hayashi,Kiyoshi Takeda,Daron M Standley,Eva-Maria Frickel,Masahiro Yamamoto,Proceedings of the National Academy of Sciences of the United States of America,Vol. 112,No. 33,p. E4581-90-E4590,2015年08月18日,研究論文(学術雑誌)
  • Selective and strain-specific NFAT4 activation by the Toxoplasma gondii polymorphic dense granule protein GRA6.,Ji Su Ma,Miwa Sasai,Jun Ohshima,Youngae Lee,Hironori Bando,Kiyoshi Takeda,Masahiro Yamamoto,The Journal of experimental medicine,Vol. 211,No. 10,p. 2013-32,2014年09月22日,研究論文(学術雑誌)
  • Role of mouse and human autophagy proteins in IFN-γ-induced cell-autonomous responses against Toxoplasma gondii.,Jun Ohshima,Youngae Lee,Miwa Sasai,Tatsuya Saitoh,Ji Su Ma,Naganori Kamiyama,Yoshiharu Matsuura,Suh Pann-Ghill,Mikako Hayashi,Shigeyuki Ebisu,Kiyoshi Takeda,Shizuo Akira,Masahiro Yamamoto,Journal of immunology (Baltimore, Md. : 1950),Vol. 192,No. 7,p. 3328-35,2014年04月01日,研究論文(学術雑誌)
  • A cluster of interferon-γ-inducible p65 GTPases plays a critical role in host defense against Toxoplasma gondii.,Masahiro Yamamoto,Megumi Okuyama,Ji Su Ma,Taishi Kimura,Naganori Kamiyama,Hiroyuki Saiga,Jun Ohshima,Miwa Sasai,Hisako Kayama,Toru Okamoto,David C S Huang,Dominique Soldati-Favre,Kyoji Horie,Junji Takeda,Kiyoshi Takeda,Immunity,Vol. 37,No. 2,p. 302-13,2012年08月24日,研究論文(学術雑誌)
  • ATF6beta is a host cellular target of the Toxoplasma gondii virulence factor ROP18.,Masahiro Yamamoto,Ji Su Ma,Christina Mueller,Naganori Kamiyama,Hiroyuki Saiga,Emi Kubo,Taishi Kimura,Toru Okamoto,Megumi Okuyama,Hisako Kayama,Kisaburo Nagamune,Seiji Takashima,Yoshiharu Matsuura,Dominique Soldati-Favre,Kiyoshi Takeda,The Journal of experimental medicine,Vol. 208,No. 7,p. 1533-46,2011年07月04日,研究論文(学術雑誌)
  • E2 polyubiquitin-conjugating enzyme Ubc13 in keratinocytes is essential for epidermal integrity,Koji Sayama,Masahiro Yamamoto,Yuji Shirakata,Yasushi Hanakawa,Satoshi Hirakawa,Xiuju Dai,Mikiko Tohyama,Sho Tokumaru,Myoung Sook Shin,Hiroaki Sakurai,Shizuo Akira,Koji Hashimoto,Journal of Biological Chemistry,Vol. 285,No. 39,p. 30042-30049,2010年09月24日,研究論文(学術雑誌)
  • A single polymorphic amino acid on Toxoplasma gondii kinase ROP16 determines the direct and strain-specific activation of Stat3.,Masahiro Yamamoto,Daron M Standley,Seiji Takashima,Hiroyuki Saiga,Megumi Okuyama,Hisako Kayama,Emi Kubo,Hiroshi Ito,Mutsumi Takaura,Tadashi Matsuda,Dominique Soldati-Favre,Kiyoshi Takeda,The Journal of experimental medicine,Vol. 206,No. 12,p. 2747-60,2009年11月23日,研究論文(学術雑誌)
  • Enhanced TLR-mediated NF-IL6-dependent gene expression by Trib1 deficiency,Masahiro Yamamoto,Satoshi Uematsu,Toru Okamoto,Yoshiharu Matsuura,Shintaro Sato,Himanshu Kumar,Takashi Satoh,Tatsuya Saitoh,Kiyoshi Takeda,Ken J. Ishii,Osamu Takeuchi,Taro Kawai,Shizuo Akira,Journal of Experimental Medicine,Vol. 204,No. 9,p. 2233-2239,2007年09月03日,研究論文(学術雑誌)
  • Cutting edge: Pivotal function of Ubc13 in thymocyte TCR signaling,Masahiro Yamamoto,Shintaro Sato,Tatsuya Saitoh,Hiroaki Sakurai,Satoshi Uematsu,Taro Kawai,Ken J. Ishii,Osamu Takeuchi,Shizuo Akira,Journal of Immunology,Vol. 177,No. 11,p. 7520-7524,2006年12月01日,研究論文(学術雑誌)
  • Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling,Masahiro Yamamoto,Toru Okamoto,Kiyoshi Takeda,Shintaro Sato,Hideki Sanjo,Satoshi Uematsu,Tatsuya Saitoh,Naoki Yamamoto,Hiroaki Sakurai,Ken J. Ishii,Shoji Yamaoka,Taro Kawai,Yoshiharu Matsuura,Osamu Takeuchi,Shizuo Akira,Nature Immunology,Vol. 7,No. 9,p. 962-970,2006年09月,研究論文(学術雑誌)
  • Regulation of Toll/IL-1-receptor-mediated gene expression by the inducible nuclear protein IκBζ,Masahiro Yamamoto,Soh Yamazaki,Satoshi Uematsu,Shintaro Sato,Hiroaki Hemmmi,Katsuaki Hoshino,Tsuneyasu Kaisho,Hirotaka Kuwata,Osamu Takeuchi,Koichiro Takeshige,Tatsuya Saitoh,Shoji Yamaoka,Naoki Yamamoto,Shunsuke Yamamoto,Tatsushi Muta,Kiyoshi Takeda,Shizuo Akira,Nature,Vol. 430,No. 6996,p. 218-222,2004年07月08日,研究論文(学術雑誌)
  • TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway,Masahiro Yamamoto,Shintaro Sato,Hiroaki Hemmi,Satoshi Uematsu,Katsuaki Hoshino,Tsuneyasu Kaisho,Osamu Takeuchi,Kiyoshi Takeda,Shizuo Akira,Nature Immunology,Vol. 4,No. 11,p. 1144-1150,2003年11月,研究論文(学術雑誌)
  • Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway,Masahiro Yamamoto,Shintaro Sato,Hiroaki Hemmi,Katsuaki Hoshino,Tsuneyasu Kaisho,Hideki Sanjo,Osamu Takeuchi,Masanaka Sugiyama,Masaru Okabe,Kiyoshi Takeda,Shizuo Akira,Science,Vol. 301,No. 5633,p. 640-643,2003年08月01日,研究論文(学術雑誌)
  • Cutting edge: A novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-β promoter in the Toll-like receptor signaling,Masahiro Yamamoto,Shintaro Sato,Kiyotoshi Mori,Katsuaki Hoshino,Osamu Takeuchi,Kiyoshi Takeda,Shizuo Akira,Journal of Immunology,Vol. 169,No. 12,p. 6668-6672,2002年12月15日,研究論文(学術雑誌)
  • Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4,Masahiro Yamamoto,Shintaro Sato,Hiroaki Hemmi,Hideki Sanjo,Satoshi Uematsu,Tsuneyasu Kaisho,Katsuaki Hoshino,Osamu Takeuchi,Masaya Kobayashi,Takashi Fujita,Kiyoshi Takeda,Shizuo Akira,Nature,Vol. 420,No. 6913,p. 324-329,2002年11月21日,研究論文(学術雑誌)
  • Chlamydia evasion of neutrophil host defense results in NLRP3 dependent myeloid-mediated sterile inflammation through the purinergic P2X7 receptor,Chunfu Yang,Lei Lei,John W. Marshall Collins,Michael Briones,Li Ma,Gail L. Sturdevant,Hua Su,Anuj K. Kashyap,David Dorward,Kevin W. Bock,Ian N. Moore,Christine Bonner,Chih-Yu Chen,Craig A. Martens,Stacy Ricklefs,Masahiro Yamamoto,Kiyoshi Takeda,Yoichiro Iwakura,Grant McClarty,Harlan D. Caldwell,Nature Communications,Springer Science and Business Media LLC,Vol. 12,No. 1,2021年09月,研究論文(学術雑誌)
  • An infectivity-enhancing site on the SARS-CoV-2 spike protein targeted by antibodies,Yafei Liu,Wai Tuck Soh,Jun ichi Kishikawa,Mika Hirose,Emi E. Nakayama,Songling Li,Miwa Sasai,Tatsuya Suzuki,Asa Tada,Akemi Arakawa,Sumiko Matsuoka,Kanako Akamatsu,Makoto Matsuda,Chikako Ono,Shiho Torii,Kazuki Kishida,Hui Jin,Wataru Nakai,Noriko Arase,Atsushi Nakagawa,Maki Matsumoto,Yukoh Nakazaki,Yasuhiro Shindo,Masako Kohyama,Keisuke Tomii,Koichiro Ohmura,Shiro Ohshima,Toru Okamoto,Masahiro Yamamoto,Hironori Nakagami,Yoshiharu Matsuura,Takayuki Kato,Masato Okada,Daron M. Standley,Tatsuo Shioda,Hisashi Arase,Cell,Vol. 184,No. 13,p. 3452-3466.e18,2021年06月24日,研究論文(学術雑誌)
  • Hepatitis C virus modulates signal peptide peptidase to alter host protein processing.,Junki Hirano,Sachiyo Yoshio,Yusuke Sakai,Li Songling,Tatsuya Suzuki,Yumi Itoh,He Zhang,David Virya Chen,Saori Haga,Hiroko Oomori,Takahiro Kodama,Yusuke Maeda,Yoshihiro Ono,Yu Takahashi,Daron M Standley,Masahiro Yamamoto,Kohji Moriishi,Kyoji Moriya,Tatsuya Kanto,Tetsuo Takehara,Kazuhiko Koike,Yoshiharu Matsuura,Toru Okamoto,Proceedings of the National Academy of Sciences of the United States of America,Vol. 118,No. 22,2021年06月01日,研究論文(学術雑誌)
  • Toxoplasma gondii GRA60 is an effector protein that modulates host cell autonomous immunity and contributes to virulence.,Mary Akinyi Nyonda,Pierre-Mehdi Hammoudi,Shu Ye,Jessica Maire,Jean-Baptiste Marq,Masahiro Yamamoto,Dominique Soldati-Favre,Cellular microbiology,Vol. 23,No. 2,2021年02月,研究論文(学術雑誌)
  • Osteoclast fusion and bone loss are restricted by interferon inducible guanylate binding proteins.,David E Place,R K Subbarao Malireddi,Jieun Kim,Peter Vogel,Masahiro Yamamoto,Thirumala-Devi Kanneganti,Nature communications,Vol. 12,No. 1,p. 496-496,2021年01月21日,研究論文(学術雑誌)
  • ESRRA (estrogen related receptor alpha) is a critical regulator of intestinal homeostasis through activation of autophagic flux via gut microbiota.,Sup Kim,June-Young Lee,Seul Gi Shin,Jin Kyung Kim,Prashanta Silwal,Young Jae Kim,Na-Ri Shin,Pil Soo Kim,Minho Won,Sang-Hee Lee,Soo Yeon Kim,Miwa Sasai,Masahiro Yamamoto,Jin-Man Kim,Jin-Woo Bae,Eun-Kyeong Jo,Autophagy,2020年11月10日,研究論文(学術雑誌)
  • Irgm2 and Gate-16 cooperatively dampen Gram-negative bacteria-induced caspase-11 response.,Elif Eren,Rémi Planès,Salimata Bagayoko,Pierre-Jean Bordignon,Karima Chaoui,Audrey Hessel,Karin Santoni,Miriam Pinilla,Brice Lagrange,Odile Burlet-Schiltz,Jonathan C Howard,Thomas Henry,Masahiro Yamamoto,Etienne Meunier,EMBO reports,Vol. 21,No. 11,2020年11月05日,研究論文(学術雑誌)
  • LC3 lipidation is essential for TFEB activation during the lysosomal damage response to kidney injury,Shuhei Nakamura,Saki Shigeyama,Satoshi Minami,Takayuki Shima,Shiori Akayama,Tomoki Matsuda,Alessandra Esposito,Gennaro Napolitano,Akiko Kuma,Tomoko Namba-Hamano,Jun Nakamura,Kenichi Yamamoto,Miwa Sasai,Ayaka Tokumura,Mika Miyamoto,Yukako Oe,Toshiharu Fujita,Seigo Terawaki,Atsushi Takahashi,Maho Hamasaki,Masahiro Yamamoto,Yukinori Okada,Masaaki Komatsu,Takeharu Nagai,Yoshitsugu Takabatake,Haoxing Xu,Yoshitaka Isaka,Andrea Ballabio,Tamotsu Yoshimori,Nature Cell Biology,Vol. 22,No. 10,p. 1252-1263,2020年10月01日,研究論文(学術雑誌)
  • Human GBP1 Differentially Targets Salmonella and Toxoplasma to License Recognition of Microbial Ligands and Caspase-Mediated Death.,Daniel Fisch,Barbara Clough,Marie-Charlotte Domart,Vesela Encheva,Hironori Bando,Ambrosius P Snijders,Lucy M Collinson,Masahiro Yamamoto,Avinash R Shenoy,Eva-Maria Frickel,Cell reports,Vol. 32,No. 6,p. 108008-108008,2020年08月11日,研究論文(学術雑誌)
  • Naïve CD8 T cell IFNγ responses to a vacuolar antigen are regulated by an inflammasome-independent NLRP3 pathway and Toxoplasma gondii ROP5.,Angel K Kongsomboonvech,Felipe Rodriguez,Anh L Diep,Brandon M Justice,Brayan E Castallanos,Ana Camejo,Debanjan Mukhopadhyay,Gregory A Taylor,Masahiro Yamamoto,Jeroen P J Saeij,Michael L Reese,Kirk D C Jensen,PLoS pathogens,Vol. 16,No. 8,2020年08月,研究論文(学術雑誌)
  • Guanylate Binding Proteins Restrict Leishmania donovani Growth in Nonphagocytic Cells Independent of Parasitophorous Vacuolar Targeting.,Arun Kumar Haldar,Utsav Nigam,Masahiro Yamamoto,Jörn Coers,Neena Goyal,mBio,Vol. 11,No. 4,p. 1-19,2020年07月28日,研究論文(学術雑誌)
  • Guanylate-Binding Proteins Are Critical for Effective Control of Francisella tularensis Strains in a Mouse Co-Culture System of Adaptive Immunity.,Nasibeh Mohammadi,Helena Lindgren,Igor Golovliov,Kjell Eneslätt,Masahiro Yamamoto,Amandine Martin,Thomas Henry,Anders Sjöstedt,Frontiers in cellular and infection microbiology,Vol. 10,p. 594063-594063,2020年,研究論文(学術雑誌)
  • Interferon inducible GBPs restrict Burkholderia thailandensis motility induced cell-cell fusion,David E. Place,Benoit Briard,Parimal Samir,Rajendra Karki,Anannya Bhattacharya,Clifford S. Guy,Jennifer L. Peters,Sharon Frase,Peter Vogel,Geoffrey Neale,Masahiro Yamamoto,Thirumala Devi Kanneganti,PLoS Pathogens,Vol. 16,No. 3,2020年,研究論文(学術雑誌)
  • Toxoplasma gondii Dense Granule Proteins 7, 14, and 15 Are Involved in Modification and Control of the Immune Response Mediated via NF-κB Pathway.,Fumiaki Ihara,Ragab M Fereig,Yuu Himori,Kyohko Kameyama,Kosuke Umeda,Sachi Tanaka,Rina Ikeda,Masahiro Yamamoto,Yoshifumi Nishikawa,Frontiers in immunology,Vol. 11,p. 1709-1709,2020年,研究論文(学術雑誌)
  • Innate, adaptive, and cell-autonomous immunity against Toxoplasma gondii infection.,Miwa Sasai,Masahiro Yamamoto,Experimental & molecular medicine,Vol. 51,No. 12,p. 1-10,2019年12月11日,研究論文(学術雑誌)
  • Phospholipase C-β1 potentiates glucose-stimulated insulin secretion,Hyeon Jeong Hwang,Yong Ryoul Yang,Hye Yun Kim,Yoonji Choi,Kyoung Su Park,Ho Lee,Ji Su Ma,Masahiro Yamamoto,Jaeyoon Kim,Young Chan Chae,Jang Hyun Choi,Lucio Cocco,Per Olof Berggren,Hyun Jun Jang,Pann Ghill Suh,FASEB Journal,Vol. 33,No. 10,p. 10668-10679,2019年10月01日,研究論文(学術雑誌)
  • Metabolic adaptation to glycolysis is a basic defense mechanism of macrophages for Mycobacterium tuberculosis infection,Mayuko Osada-Oka,Nobuhito Goda,Hiroyuki Saiga,Masahiro Yamamoto,Kiyoshi Takeda,Yuriko Ozeki,Takehiro Yamaguchi,Tomoyoshi Soga,Yu Tateishi,Katsuyuki Miura,Daisuke Okuzaki,Kazuo Kobayashi,Sohkichi Matsumoto,International Immunology,Vol. 31,No. 12,p. 781-793,2019年08月01日,研究論文(学術雑誌)
  • Human GBP1 is a microbe-specific gatekeeper of macrophage apoptosis and pyroptosis,Daniel Fisch,Hironori Bando,Barbara Clough,Veit Hornung,Masahiro Yamamoto,Avinash R. Shenoy,Eva Maria Frickel,EMBO Journal,Vol. 38,No. 13,2019年07月01日,研究論文(学術雑誌)
  • Human GBP1 is a microbe-specific gatekeeper of macrophage apoptosis and pyroptosis.,Daniel Fisch,Hironori Bando,Barbara Clough,Veit Hornung,Masahiro Yamamoto,Avinash R Shenoy,Eva-Maria Frickel,The EMBO journal,Vol. 38,No. 13,2019年07月01日,研究論文(学術雑誌)
  • Cholera toxin B induces interleukin-1β production from resident peritoneal macrophages through the pyrin inflammasome as well as the NLRP3 inflammasome,Takashi Orimo,Izumi Sasaki,Hiroaki Hemmi,Toshiya Ozasa,Yuri Fukuda-Ohta,Tomokazu Ohta,Mio Morinaka,Mariko Kitauchi,Takako Yamaguchi,Yayoi Sato,Takashi Tanaka,Katsuaki Hoshino,Kei Ichi Katayama,Shinji Fukuda,Kensuke Miyake,Masahiro Yamamoto,Takashi Satoh,Koichi Furukawa,Etsushi Kuroda,Ken J. Ishii,Kiyoshi Takeda,Tsuneyasu Kaisho,International Immunology,Vol. 31,No. 10,p. 657-668,2019年05月27日,研究論文(学術雑誌)
  • USP15 participates in hepatitis C virus propagation through regulation of viral RNA translation and lipid droplet formation,Shinji Kusakabe,Tatsuya Suzuki,Yukari Sugiyama,Saori Haga,Kanako Horike,Makoto Tokunaga,Junki Hirano,He Zhang,David Virya Chen,Hanako Ishiga,Yasumasa Komoda,Chikako Ono,Takasuke Fukuhara,Masahiro Yamamoto,Masahito Ikawa,Takashi Satoh,Shizuo Akira,Tomohisa Tanaka,Kohji Moriishi,Moto Fukai,Akinobu Taketomi,Sachiyo Yoshio,Tatsuya Kanto,Tetsuro Suzuki,Toru Okamoto,Yoshiharu Matsuura,Journal of Virology,Vol. 93,No. 6,2019年03月01日,研究論文(学術雑誌)
  • Fungal ligands released by innate immune effectors promote inflammasome activation during Aspergillus fumigatus infection,Benoit Briard,Rajendra Karki,R. K.Subbarao Malireddi,Anannya Bhattacharya,David E. Place,Jayadev Mavuluri,Jennifer L. Peters,Peter Vogel,Masahiro Yamamoto,Thirumala Devi Kanneganti,Nature Microbiology,Vol. 4,No. 2,p. 316-327,2019年02月01日,研究論文(学術雑誌)
  • GABAergic signaling linked to autophagy enhances host protection against intracellular bacterial infections,Jin Kyung Kim,Yi Sak Kim,Hye Mi Lee,Hyo Sun Jin,Chiranjivi Neupane,Sup Kim,Sang Hee Lee,Jung Joon Min,Miwa Sasai,Jae Ho Jeong,Seong Kyu Choe,Jin Man Kim,Masahiro Yamamoto,Hyon E. Choy,Jin Bong Park,Eun Kyeong Jo,Nature Communications,Vol. 9,No. 1,p. 4184-4184,2018年12月01日,研究論文(学術雑誌)
  • Guanylate binding proteins facilitate caspase-11-dependent pyroptosis in response to type 3 secretion system-negative Pseudomonas aeruginosa,Arjun Balakrishnan,Rajendra Karki,Brent Berwin,Masahiro Yamamoto,Thirumala Devi Kanneganti,Cell Death Discovery,Vol. 4,No. 1,p. 3-3,2018年12月01日,研究論文(学術雑誌)
  • Molecular mechanisms of Streptococcus pneumoniae-targeted autophagy via pneumolysin, Golgi-resident Rab41, and Nedd4-1-mediated K63-linked ubiquitination,Michinaga Ogawa,Ryuta Matsuda,Naoki Takada,Mikado Tomokiyo,Shouji Yamamoto,Sayaka Shizukusihi,Toshiyuki Yamaji,Yuko Yoshikawa,Mitsutaka Yoshida,Isei Tanida,Masato Koike,Miyo Murai,Hidetoshi Morita,Haruko Takeyama,Akihide Ryo,Jun Lin Guan,Masahiro Yamamoto,Jun ichiro Inoue,Toru Yanagawa,Mitsunori Fukuda,Hiroshi Kawabe,Makoto Ohnishi,Cellular Microbiology,Vol. 20,No. 8,2018年08月,研究論文(学術雑誌)
  • Constitutive Interferon Maintains GBP Expression Required for Release of Bacterial Components Upstream of Pyroptosis and Anti-DNA Responses,Beiyun C. Liu,Joseph Sarhan,Alexander Panda,Hayley I. Muendlein,Vladimir Ilyukha,Jörn Coers,Masahiro Yamamoto,Ralph R. Isberg,Alexander Poltorak,Cell Reports,Vol. 24,No. 1,p. 155-168.e5,2018年07月03日,研究論文(学術雑誌)
  • A nonpyroptotic ifn-g–triggered cell death mechanism in nonphagocytic cells promotes salmonella clearance in vivo,Justin P. Ingram,Sarah Tursi,Ting Zhang,Wei Guo,Chaoran Yin,Meghan A. Wynosky-Dolfi,Joris Van der Heijden,Kathy Q. Cai,Masahiro Yamamoto,B. Brett Finlay,Igor E. Brodsky,Sergei I. Grivennikov,Çagla Tükel,Siddharth Balachandran,Journal of Immunology,Vol. 200,No. 10,p. 3626-3634,2018年05月15日,研究論文(学術雑誌)
  • LPS targets host guanylate-binding proteins to the bacterial outer membrane for non-canonical inflammasome activation,José Carlos Santos,Mathias S. Dick,Brice Lagrange,Daniel Degrandi,Klaus Pfeffer,Masahiro Yamamoto,Etienne Meunier,Pawel Pelczar,Thomas Henry,Petr Broz,EMBO Journal,Vol. 37,No. 6,2018年03月15日,研究論文(学術雑誌)
  • Host immune responses to Toxoplasma gondii.,Miwa Sasai,Ariel Pradipta,Masahiro Yamamoto,International immunology,Vol. 30,No. 3,p. 113-119,2018年03月10日,研究論文(学術雑誌)
  • Introduction: Interactions between the immune system and parasites special issue,Cevayir Coban,Masahiro Yamamoto,International Immunology,Vol. 30,No. 3,p. 91-91,2018年03月01日,研究論文(学術雑誌)
  • Characterization of SPP inhibitors suppressing propagation of HCV and protozoa.,Junki Hirano,Toru Okamoto,Yukari Sugiyama,Tatsuya Suzuki,Shinji Kusakabe,Makoto Tokunaga,Takasuke Fukuhara,Miwa Sasai,Takahiro Tougan,Yasue Matsunaga,Kazuo Yamashita,Yusuke Sakai,Masahiro Yamamoto,Toshihiro Horii,Daron M Standley,Kohji Moriishi,Kyoji Moriya,Kazuhiko Koike,Yoshiharu Matsuura,Proceedings of the National Academy of Sciences of the United States of America,Vol. 114,No. 50,p. E10782-E10791-E10791,2017年12月12日,研究論文(学術雑誌)
  • Critical role of CREBH-mediated induction of transforming growth factor β2 by hepatitis C virus infection in fibrogenic responses in hepatic stellate cells,Takeshi Chida,Masahiko Ito,Kenji Nakashima,Yumi Kanegae,Takuya Aoshima,Shuji Takabayashi,Kazuhito Kawata,Yoshimi Nakagawa,Masahiro Yamamoto,Hitoshi Shimano,Tomokazu Matsuura,Yoshimasa Kobayashi,Takafumi Suda,Tetsuro Suzuki,Hepatology,Vol. 66,No. 5,p. 1430-1443,2017年11月,研究論文(学術雑誌)
  • IFN-γ extends the immune functions of Guanylate Binding Proteins to inflammasome-independent antibacterial activities during Francisella novicida infection,Pierre Wallet,Sacha Benaoudia,Amandine Mosnier,Brice Lagrange,Amandine Martin,Helena Lindgren,Igor Golovliov,Fanny Michal,Pauline Basso,Sophia Djebali,Angelina Provost,Omran Allatif,Etienne Meunier,Petr Broz,Masahiro Yamamoto,Bénédicte F. Py,Eric Faudry,Anders Sjöstedt,Thomas Henry,PLoS Pathogens,Vol. 13,No. 10,2017年10月,研究論文(学術雑誌)
  • Inflammasome activation by bacterial outer membrane vesicles requires guanylate binding proteins,Ryan Finethy,Sarah Luoma,Nichole Orench-Rivera,Eric M. Feeley,Arun K. Haldar,Masahiro Yamamoto,Thirumala Devi Kanneganti,Meta J. Kuehn,Jörn Coers,mBio,Vol. 8,No. 5,2017年09月,研究論文(学術雑誌)
  • Viral Replication Complexes Are Targeted by LC3-Guided Interferon-Inducible GTPases,Scott B. Biering,Jayoung Choi,Rachel A. Halstrom,Hailey M. Brown,Wandy L. Beatty,Sanghyun Lee,Broc T. McCune,Erin Dominici,Lelia E. Williams,Robert C. Orchard,Craig B. Wilen,Masahiro Yamamoto,Jörn Coers,Gregory A. Taylor,Seungmin Hwang,Cell Host and Microbe,Vol. 22,No. 1,p. 74-85.e7,2017年07月12日,研究論文(学術雑誌)
  • Guanylate binding proteins regulate inflammasome activation in response to hyperinjected Yersinia translocon components,Erin E. Zwack,Eric M. Feeley,Amanda R. Burton,Baofeng Hu,Masahiro Yamamoto,Thirumala Devi Kanneganti,James B. Bliska,Jörn Coers,Igor E. Brodsky,Infection and Immunity,Vol. 85,No. 10,2017年,研究論文(学術雑誌)
  • The thalamic mGluR1-PLCβ4 pathway is critical in sleep architecture,Joohyeon Hong,Jungryun Lee,Kiyeong Song,Go Eun Ha,Yong Ryoul Yang,Ji Su Ma,Masahiro Yamamoto,Hee Sup Shin,Pann Ghill Suh,Eunji Cheong,Molecular Brain,Vol. 9,No. 1,p. 100-100,2016年12月21日,研究論文(学術雑誌)
  • IRGB10 Liberates Bacterial Ligands for Sensing by the AIM2 and Caspase-11-NLRP3 Inflammasomes,Si Ming Man,Rajendra Karki,Miwa Sasai,David E. Place,Sannula Kesavardhana,Jamshid Temirov,Sharon Frase,Qifan Zhu,R. K.Subbarao Malireddi,Teneema Kuriakose,Jennifer L. Peters,Geoffrey Neale,Scott A. Brown,Masahiro Yamamoto,Thirumala Devi Kanneganti,Cell,Vol. 167,No. 2,p. 382-396.e17,2016年10月06日,研究論文(学術雑誌)
  • The P2X4 receptor is required for neuroprotection via ischemic preconditioning,Tomohiko Ozaki,Rieko Muramatsu,Miwa Sasai,Masahiro Yamamoto,Yoshiaki Kubota,Toshiyuki Fujinaka,Toshiki Yoshimine,Toshihide Yamashita,Scientific Reports,Vol. 6,2016年05月13日,研究論文(学術雑誌)
  • TRC8-dependent degradation of hepatitis C virus immature core protein regulates viral propagation and pathogenesis,Sayaka Aizawa,Toru Okamoto,Yukari Sugiyama,Takahisa Kouwaki,Ayano Ito,Tatsuya Suzuki,Chikako Ono,Takasuke Fukuhara,Masahiro Yamamoto,Masayasu Okochi,Nobuhiko Hiraga,Michio Imamura,Kazuaki Chayama,Ryosuke Suzuki,Ikuo Shoji,Kohji Moriishi,Kyoji Moriya,Kazuhiko Koike,Yoshiharu Matsuura,Nature Communications,Vol. 7,2016年05月04日,研究論文(学術雑誌)
  • Lypd8 promotes the segregation of flagellated microbiota and colonic epithelia,Ryu Okumura,Takashi Kurakawa,Takashi Nakano,Hisako Kayama,Makoto Kinoshita,Daisuke Motooka,Kazuyoshi Gotoh,Taishi Kimura,Naganori Kamiyama,Takashi Kusu,Yoshiyasu Ueda,Hong Wu,Hideki Iijima,Soumik Barman,Hideki Osawa,Hiroshi Matsuno,Junichi Nishimura,Yusuke Ohba,Shota Nakamura,Tetsuya Iida,Masahiro Yamamoto,Eiji Umemoto,Koichi Sano,Kiyoshi Takeda,Nature,Vol. 532,No. 7597,p. 117-121,2016年04月,研究論文(学術雑誌)
  • Fundamental Roles of the Golgi-Associated Toxoplasma Aspartyl Protease, ASP5, at the Host-Parasite Interface.,Pierre-Mehdi Hammoudi,Damien Jacot,Christina Mueller,Manlio Di Cristina,Sunil Kumar Dogga,Jean-Baptiste Marq,Julia Romano,Nicolò Tosetti,Juan Dubrot,Yalin Emre,Matteo Lunghi,Isabelle Coppens,Masahiro Yamamoto,Daniel Sojka,Paco Pino,Dominique Soldati-Favre,PLoS pathogens,Vol. 11,No. 10,2015年10月,研究論文(学術雑誌)
  • Erratum: Class-specific regulation of pro-inflammatory genes by MyD88 pathways and IκBζ (The Journal of Biological Chemistry (2008) 283 (12468-12477)),Hisako Kayama,Vladimir R. Ramirez-Carrozzi,Masahiro Yamamoto,Taketoshi Mizutani,Hirotaka Kuwata,Hideo Iba,Makoto Matsumoto,Kenya Honda,Stephen T. Smale,Kiyoshi Takeda,Journal of Biological Chemistry,Vol. 290,No. 37,p. 22446-22446,2015年09月11日,研究論文(学術雑誌)
  • MTOR complex signaling through the SEMA4A-plexin B2 axis is required for optimal activation and differentiation of CD8<sup>+</sup> T cells,Daisuke Ito,Satoshi Nojima,Masayuki Nishide,Tatsusada Okuno,Hyota Takamatsu,Sujin Kang,Tetsuya Kimura,Yuji Yoshida,Keiko Morimoto,Yohei Maeda,Takashi Hosokawa,Toshihiko Toyofuku,Jun Ohshima,Daisuke Kamimura,Masahiro Yamamoto,Masaaki Murakami,Eiichi Morii,Hiromi Rakugi,Yoshitaka Isaka,Atsushi Kumanogoh,Journal of Immunology,Vol. 195,No. 3,p. 934-943,2015年08月01日,研究論文(学術雑誌)
  • The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection,Si Ming Man,Rajendra Karki,R. K.Subbarao Malireddi,Geoffrey Neale,Peter Vogel,Masahiro Yamamoto,Mohamed Lamkanfi,Thirumala Devi Kanneganti,Nature Immunology,Vol. 16,No. 5,p. 467-475,2015年05月28日,研究論文(学術雑誌)
  • Guanylate-binding proteins promote activation of the AIM2 inflammasome during infection with Francisella novicida,Etienne Meunier,Pierre Wallet,Roland F. Dreier,Stéphanie Costanzo,Leonie Anton,Sebastian Rühl,Sébastien Dussurgey,Mathias S. Dick,Anne Kistner,Mélanie Rigard,Daniel Degrandi,Klaus Pfeffer,Masahiro Yamamoto,Thomas Henry,Petr Broz,Nature Immunology,Vol. 16,No. 5,p. 476-484,2015年05月28日,研究論文(学術雑誌)
  • Erratum: Class-specific regulation of pro-inflammatory genes by MyD88 pathways and IκBζ (The Journal of Biological Chemistry (2008) 283 (12468-12477),Hisako Kayama,Vladimir R. Ramirez-Carrozzi,Masahiro Yamamoto,Taketoshi Mizutani,Hirotaka Kuwata,Hideo Iba,Makoto Matsumoto,Kenya Honda,Stephen T. Smale,Kiyoshi Takeda,Journal of Biological Chemistry,Vol. 290,No. 8,p. 4815-4815,2015年02月20日,研究論文(学術雑誌)
  • Guanylate binding proteins enable rapid activation of canonical and noncanonical inflammasomes in Chlamydia-infected macrophages,Ryan Finethy,Ine Jorgensen,Arun K. Haldar,Marcel R. De Zoete,Till Strowig,Richard A. Flavell,Masahiro Yamamoto,Uma M. Nagarajan,Edward A. Miao,Jörn Coers,Infection and Immunity,Vol. 83,No. 12,p. 4740-4749,2015年,研究論文(学術雑誌)
  • Amphipathic α-Helices in Apolipoproteins Are Crucial to the Formation of Infectious Hepatitis C Virus Particles,Takasuke Fukuhara,Masami Wada,Shota Nakamura,Chikako Ono,Mai Shiokawa,Satomi Yamamoto,Takashi Motomura,Toru Okamoto,Daisuke Okuzaki,Masahiro Yamamoto,Izumu Saito,Takaji Wakita,Kazuhiko Koike,Yoshiharu Matsuura,PLoS Pathogens,Vol. 10,No. 12,2014年12月01日,研究論文(学術雑誌)
  • Guanylate binding proteins promote caspase-11-dependent pyroptosis in response to cytoplasmic LPS,Danielle M. Pilla,Jon A. Hagar,Arun K. Haldar,Ashley K. Mason,Daniel Degrandi,Klaus Pfeffer,Robert K. Ernst,Masahiro Yamamoto,Edward A. Miao,Jörn Coers,Proceedings of the National Academy of Sciences of the United States of America,Vol. 111,No. 16,p. 6046-6051,2014年04月,研究論文(学術雑誌)
  • Innate immune response induced by baculovirus attenuates transgene expression in mammalian cells,Chikako Ono,Akinori Ninomiya,Satomi Yamamoto,Takayuki Abe,Xiauyu Wen,Takasuke Fukuhara,Miwa Sasai,Masahiro Yamamoto,Tatsuya Saitoh,Takashi Satoh,Taro Kawai,Ken J. Ishii,Shizuo Akira,Toru Okamoto,Yoshiharu Matsuura,Journal of Virology,Vol. 88,No. 4,p. 2157-2167,2014年02月,研究論文(学術雑誌)
  • Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases,Etienne Meunier,Mathias S. Dick,Roland F. Dreier,Nura Schürmann,Daniela Kenzelmann Broz,Søren Warming,Merone Roose-Girma,Dirk Bumann,Nobuhiko Kayagaki,Kiyoshi Takeda,Masahiro Yamamoto,Petr Broz,Nature,Vol. 509,No. 7500,p. 366-370,2014年,研究論文(学術雑誌)
  • The E2-like conjugation enzyme Atg3 promotes binding of IRG and Gbp proteins to Chlamydia- and Toxoplasma-containing vacuoles and host resistance.,Arun K Haldar,Anthony S Piro,Danielle M Pilla,Masahiro Yamamoto,Jörn Coers,PloS one,Vol. 9,No. 1,2014年,研究論文(学術雑誌)
  • Erratum: NF-κB activation by the Toll-IL-1 receptor domain protein MyD88 adapter-like is regulated by caspase-1 (Proceedings of the National Academy of Sciences of the United States of America (2007) 110 (3372-3377) DOI: 10.1073/pnas.0608100104),Sinead M. Miggin,Eva Pålsson-McDermott,Aisling Dunne,Caroline Jefferies,Emmanuel Pinteaux,Kathy Banahan,Caroline Murphy,Paul Moynagh,Masahiro Yamamoto,Shizuo Akira,Nancy Rothwell,Douglas Golenbock,Katherine A. Fitzgerald,Luke A.J. O'Neill,Proceedings of the National Academy of Sciences of the United States of America,Vol. 110,No. 43,2013年10月22日,研究論文(学術雑誌)
  • Toll-like receptor 3 and 4 signalling through the TRIF and TRAM adaptors in haematopoietic cells promotes atherosclerosis,Anna M. Lundberg,Daniel F.J. Ketelhuth,Maria E. Johansson,Norbert Gerdes,Sang Liu,Masahiro Yamamoto,Shizuo Akira,Göran K. Hansson,Cardiovascular Research,Vol. 99,No. 2,p. 364-373,2013年07月15日,研究論文(学術雑誌)
  • Subversion of host cellular functions by the apicomplexan parasites.,Louise E Kemp,Masahiro Yamamoto,Dominique Soldati-Favre,FEMS microbiology reviews,Vol. 37,No. 4,p. 607-31,2013年07月,研究論文(学術雑誌)
  • Pathogen recognition receptors: Ligands and signaling pathways by toll-like receptors,Miwa Sasai,Masahiro Yamamoto,International Reviews of Immunology,Vol. 32,No. 2,p. 116-133,2013年04月
  • Critical role of Trib1 in differentiation of tissue-resident M2-like macrophages,Takashi Satoh,Hiroyasu Kidoya,Hisamichi Naito,Masahiro Yamamoto,Naoki Takemura,Katsuhiro Nakagawa,Yoshichika Yoshioka,Eiichi Morii,Nobuyuki Takakura,Osamu Takeuchi,Shizuo Akira,Nature,Vol. 495,No. 7442,p. 524-528,2013年03月28日,研究論文(学術雑誌)
  • CREBH Determines the Severity of Sulpyrine-Induced Fatal Shock,Naganori Kamiyama,Masahiro Yamamoto,Hiroyuki Saiga,Ji Su Ma,Jun Ohshima,Sakaaki Machimura,Miwa Sasai,Taishi Kimura,Yoshiyasu Ueda,Hisako Kayama,Kiyoshi Takeda,PLoS ONE,Vol. 8,No. 2,2013年02月07日,研究論文(学術雑誌)
  • Ecto-nucleoside triphosphate diphosphohydrolase 7 controls Th17 cell responses through regulation of luminal ATP in the small intestine,Takashi Kusu,Hisako Kayama,Makoto Kinoshita,Seong Gyu Jeon,Yoshiyasu Ueda,Yoshiyuki Goto,Ryu Okumura,Hiroyuki Saiga,Takashi Kurakawa,Kayo Ikeda,Yuichi Maeda,Jun Ichi Nishimura,Yasunobu Arima,Koji Atarashi,Kenya Honda,Masaaki Murakami,Jun Kunisawa,Hiroshi Kiyono,Meinoshin Okumura,Masahiro Yamamoto,Kiyoshi Takeda,Journal of Immunology,Vol. 190,No. 2,p. 774-783,2013年01月15日,研究論文(学術雑誌)
  • Ifit1 inhibits japanese encephalitis virus replication through binding to 5= capped 2'-o unmethylated RNA,Taishi Kimura,Hiroshi Katoh,Hisako Kayama,Hiroyuki Saiga,Megumi Okuyama,Toru Okamoto,Eiji Umemoto,Yoshiharu Matsuur,Masahiro Yamamoto,Kiyoshi Takeda,Journal of Virology,Vol. 87,No. 18,p. 9997-10003,2013年,研究論文(学術雑誌)
  • Critical role of AIM2 in Mycobacterium tuberculosis infection,Hiroyuki Saiga,Shoko Kitada,Yosuke Shimada,Naganori Kamiyama,Megumi Okuyama,Masahiko Makino,Masahiro Yamamoto,Kiyoshi Takeda,International Immunology,Vol. 24,No. 10,p. 637-644,2012年10月,研究論文(学術雑誌)
  • Probiotic Bifidobacterium breve induces IL-10-producing Tr1 cells in the colon,Seong Gyu Jeon,Hisako Kayama,Yoshiyasu Ueda,Takuya Takahashi,Takashi Asahara,Hirokazu Tsuji,Noriko M. Tsuji,Hiroshi Kiyono,Ji Su Ma,Takashi Kusu,Ryu Okumura,Hiromitsu Hara,Hiroki Yoshida,Masahiro Yamamoto,Koji Nomoto,Kiyoshi Takeda,PLoS Pathogens,Vol. 8,No. 5,2012年05月,研究論文(学術雑誌)
  • Intestinal CX <inf>3</inf>C chemokine receptor 1 <sup>high</sup> (CX <inf>3</inf>CR1 <sup>high</sup>) myeloid cells prevent T-cell-dependent colitis,Hisako Kayama,Yoshiyasu Ueda,Yukihisa Sawa,Seong Gyu Jeon,Ji Su Ma,Ryu Okumura,Atsuko Kubo,Masaru Ishii,Taku Okazaki,Masaaki Murakami,Masahiro Yamamoto,Hideo Yagita,Kiyoshi Takeda,Proceedings of the National Academy of Sciences of the United States of America,Vol. 109,No. 13,p. 5010-5015,2012年03月27日,研究論文(学術雑誌)
  • Inhibition of ATF6β-dependent host adaptive immune response by a toxoplasma virulence factor ROP18,Masahiro Yamamoto,Kiyoshi Takeda,Virulence,Vol. 3,No. 1,p. 77-80,2012年,研究論文(学術雑誌)
  • A method for the generation of conditional gene-targeted mice,Masahiro Yamamoto,Kiyoshi Takeda,Methods in Molecular Biology,Vol. 757,p. 399-410,2011年,研究論文(学術雑誌)
  • Trib1 is a lipid- and myocardial infarction-associated gene that regulates hepatic lipogenesis and VLDL production in mice,Ralph Burkhardt,Sue Anne Toh,William R. Lagor,Andrew Birkeland,Michael Levin,Xiaoyu Li,Megan Robblee,Victor D. Fedorov,Masahiro Yamamoto,Takashi Satoh,Shizuo Akira,Sekar Kathiresan,Jan L. Breslow,Daniel J. Rader,Journal of Clinical Investigation,Vol. 120,No. 12,p. 4410-4414,2010年12月01日,研究論文(学術雑誌)
  • Commensal microbiota induce LPS hyporesponsiveness in colonic macrophages via the production of IL-10,Yoshiyasu Ueda,Hisako Kayama,Seong Gyu Jeon,Takashi Kusu,Yoshitaka Isaka,Hiromi Rakugi,Masahiro Yamamoto,Kiyoshi Takeda,International Immunology,Vol. 22,No. 12,p. 953-962,2010年12月,研究論文(学術雑誌)
  • Control of adipose tissue inflammation through TRB1,Anke Ostertag,Allan Jones,Adam J. Rose,Maria Liebert,Stefan Kleinsorg,Anja Reimann,Alexandros Vegiopoulos,Mauricio Berriel Diaz,Daniela Strzoda,Masahiro Yamamoto,Takashi Satoh,Shizuo Akira,Stephan Herzig,Diabetes,Vol. 59,No. 8,p. 1991-2000,2010年08月,研究論文(学術雑誌)
  • A novel in vivo inducible dendritic cell ablation model in mice,Megumi Okuyama,Hisako Kayama,Koji Atarashi,Hiroyuki Saiga,Taishi Kimura,Ari Waisman,Masahiro Yamamoto,Kiyoshi Takeda,Biochemical and Biophysical Research Communications,Vol. 397,No. 3,p. 559-563,2010年07月,研究論文(学術雑誌)
  • IκBη regulates T<inf>H</inf> 17 development by cooperating with ROR nuclear receptors,Kazuo Okamoto,Yoshiko Iwai,Masatsugu Oh-Hora,Masahiro Yamamoto,Tomohiro Morio,Kazuhiro Aoki,Keiichi Ohya,Anton M. Jetten,Shizuo Akira,Tatsushi Muta,Hiroshi Takayanagi,Nature,Vol. 464,No. 7293,p. 1381-1385,2010年04月,研究論文(学術雑誌)
  • Current views of toll-like receptor signaling pathways,Kiyoshi Takeda,Masahiro Yamamoto,Gastroenterology Research and Practice,Vol. 2010,p. 240365-240365,2010年
  • Regulation of hematopoiesis by the K63-specific ubiquitin-conjugating enzyme Ubc13,Xuefeng Wu,Masahiro Yamamoto,Shizuo Akira,Shao Cong Sun,Proceedings of the National Academy of Sciences of the United States of America,Vol. 106,No. 49,p. 20836-20841,2009年12月08日,研究論文(学術雑誌)
  • Toll-like receptor 4 signalling through MyD88 is essential to control Salmonella enterica serovar Typhimurium infection, but not for the initiation of bacterial clearance,Suzanne Talbot,Sabine Tötemeyer,Masahiro Yamamoto,Shizuo Akira,Katherine Hughes,David Gray,Tom Barr,Pietro Mastroeni,Duncan J. Maskell,Clare E. Bryant,Immunology,Vol. 128,No. 4,p. 472-483,2009年12月,研究論文(学術雑誌)
  • Two mechanistically and temporally distinct NF-κB activation pathways in IL-1 signaling,Kohsuke Yamazaki,Jin Gohda,Atsuhiro Kanayama,Yusei Miyamoto,Hiroaki Sakurai,Masahiro Yamamoto,Shizuo Akira,Hidetoshi Hayashi,Bing Su,Jun Ichiro Inoue,Science Signaling,Vol. 2,No. 93,2009年10月20日,研究論文(学術雑誌)
  • NFATc1 mediates toll-like receptor-independent innate immune responses during Trypanosoma cruzi infection,Hisako Kayama,Ritsuko Koga,Koji Atarashi,Megumi Okuyama,Taishi Kimura,Tak W. Mak,Satoshi Uematsu,Shizuo Akira,Hiroshi Takayanagi,Kenya Honda,Masahiro Yamamoto,Kiyoshi Takeda,PLoS Pathogens,Vol. 5,No. 7,2009年07月,研究論文(学術雑誌)
  • [Host immune response to Trypanosoma cruzi and its evasion mechanism].,Masahiro Yamamoto,Kiyoshi Takeda,Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme,Vol. 54,No. 8 Suppl,p. 1053-1058,2009年06月
  • TRAF6 is required for generation of the B-1a B cell compartment as well as T cell-dependent and-independent humoral immune responses,Takashi Kobayashi,Tae Soo Kim,Anand Jacob,Matthew C. Walsh,Yuho Kadono,Ezequiel Fuentes-Pananá,Tomoko Yoshioka,Akihiko Yoshimura,Masahiro Yamamoto,Tsuneyasu Kaisho,Shizuo Akira,John G. Monroe,Yongwon Choi,PLoS ONE,Vol. 4,No. 3,2009年03月09日,研究論文(学術雑誌)
  • Lipid a receptor TLR4-mediated signaling pathways,Shizuo Akira,Masahiro Yamamoto,Advances in Experimental Medicine and Biology,Vol. 667,p. 59-68,2009年,研究論文(学術雑誌)
  • Fra-1 negatively regulates lipopolysaccharide-mediated inflammatory responses,Hideaki Morishita,Fumiji Saito,Hisako Kayama,Koji Atarashi,Hirotaka Kuwata,Masahiro Yamamoto,Kiyoshi Takeda,International Immunology,Vol. 21,No. 4,p. 457-465,2009年,研究論文(学術雑誌)
  • Involvement of linear polyubiquitylation of NEMO in NF-κB activation,Fuminori Tokunaga,Shin Ichi Sakata,Yasushi Saeki,Yoshinori Satomi,Takayoshi Kirisako,Kiyoko Kamei,Tomoko Nakagawa,Michiko Kato,Shigeo Murata,Shoji Yamaoka,Masahiro Yamamoto,Shizuo Akira,Toshifumi Takao,Keiji Tanaka,Kazuhiro Iwai,Nature Cell Biology,Vol. 11,No. 2,p. 123-132,2009年,研究論文(学術雑誌)
  • Lipocalin 2-dependent inhibition of mycobacterial growth in alveolar epithelium,Hiroyuki Saiga,Junichi Nishimura,Hirotaka Kuwata,Megumi Okuyama,Sohkichi Matsumoto,Shintaro Sato,Makoto Matsumoto,Shizuo Akira,Yasunobu Yoshikai,Kenya Honda,Masahiro Yamamoto,Kiyoshi Takeda,Journal of Immunology,Vol. 181,No. 12,p. 8521-8527,2008年12月15日,研究論文(学術雑誌)
  • Gene-specific requirement of a nuclear protein, IκB-ζ, for promoter association of inflammatory transcription regulators,Soh Yamazaki,Susumu Matsuo,Tatsushi Muta,Masahiro Yamamoto,Shizuo Akira,Koichiro Takeshige,Journal of Biological Chemistry,Vol. 283,No. 47,p. 32404-32411,2008年11月21日,研究論文(学術雑誌)
  • ATP drives lamina propria T<inf>H</inf>17 cell differentiation,Koji Atarashi,Junichi Nishimura,Tatsuichiro Shima,Yoshinori Umesaki,Masahiro Yamamoto,Masaharu Onoue,Hideo Yagita,Naoto Ishii,Richard Evans,Kenya Honda,Kiyoshi Takeda,Nature,Vol. 455,No. 7214,p. 808-812,2008年10月09日,研究論文(学術雑誌)
  • Noncanonical E2 variant-independent function of UBC13 in promoting checkpoint protein assembly,Michael S.Y. Huen,Jun Huang,Jingsong Yuan,Masahiro Yamamoto,Shizuo Akira,Carolyn Ashley,Wei Xiao,Junjie Chen,Molecular and Cellular Biology,Vol. 28,No. 19,p. 6104-6112,2008年10月,研究論文(学術雑誌)
  • Stat6-independent tissue inflammation occurs selectively on the ocular surface and perioral skin of IκBζ<sup>-/-</sup> mice,Mayumi Ueta,Junji Hamuro,Eiichiro Ueda,Norito Katoh,Masahiro Yamamoto,Kiyoshi Takeda,Shizuo Akira,Shigeru Kinoshita,Investigative Ophthalmology and Visual Science,Vol. 49,No. 8,p. 3387-3394,2008年08月,研究論文(学術雑誌)
  • Role of nuclear IκB proteins in the regulation of host immune responses,Masahiro Yamamoto,Kiyoshi Takeda,Journal of Infection and Chemotherapy,Vol. 14,No. 4,p. 265-269,2008年08月
  • Virulent Salmonella enterica infections can be exacerbated by concomitant infection of the host with a live attenuated S. enterica vaccine via Toll-like receptor 4-dependent interleukin-10 production with the involvement of both TRIF and MyD88,Gemma L. Foster,Tom A. Barr,Andrew J. Grant,Trevelyan J. McKinley,Clare E. Bryant,Andrew MacDonald,David Gray,Masahiro Yamamoto,Shizuo Akira,Duncan J. Maskell,Pietro Mastroeni,Immunology,Vol. 124,No. 4,p. 469-479,2008年08月,研究論文(学術雑誌)
  • Class-specific regulation of pro-inflammatory genes by MyD88 pathways and IκBζ,Hisako Kayama,Vladimir R. Ramirez-Carrozzi,Masahiro Yamamoto,Taketoshi Mizutani,Hirotaka Kuwata,Hideo Iba,Makoto Matsumoto,Kenya Honda,Stephen T. Smale,Kiyoshi Takeda,Journal of Biological Chemistry,Vol. 283,No. 18,p. 12468-12477,2008年05月02日,研究論文(学術雑誌)
  • Potent antimycobacterial activity of mouse secretory leukocyte protease inhibitor,Junichi Nishimura,Hiroyuki Saiga,Shintaro Sato,Megumi Okuyama,Hisako Kayama,Hirotaka Kuwata,Sohkichi Matsumoto,Toshirou Nishida,Yoshiki Sawa,Shizuo Akira,Yasunobu Yoshikai,Masahiro Yamamoto,Kiyoshi Takeda,Journal of Immunology,Vol. 180,No. 6,p. 4032-4039,2008年03月15日,研究論文(学術雑誌)
  • Assessing the response of cells to TLR stimulation,Kiyoshi Takeda,Masahiro Yamamoto,Kenya Honda,Signaling by Toll-Like Receptors,p. 1-21,2008年01月01日,論文集(書籍)内論文
  • The human T-cell leukemia virus type 1 tax oncoprotein requires the ubiquitin-conjugating enzyme Ubc13 for NF-κB activation,Noula Shembade,Nicole S. Harhaj,Masahiro Yamamoto,Shizuo Akira,Edward W. Harhaj,Journal of Virology,Vol. 81,No. 24,p. 13735-13742,2007年12月,研究論文(学術雑誌)
  • FADD negatively regulates lipopolysaccharide signaling by impairing interleukin-1 receptor-associated kinase 1-MyD88 interaction,Rachel Zhande,Shauna M. Dauphinee,James A. Thomas,Masahiro Yamamoto,Shizuo Akira,Aly Karsan,Molecular and Cellular Biology,Vol. 27,No. 21,p. 7394-7404,2007年11月,研究論文(学術雑誌)
  • The C/EBPβ isoform 34-kDa LAP is responsible for NF-IL-6-mediated gene induction in activated macrophages, but is not essential for intracellular bacteria killing,Satoshi Uematsu,Tsuneyasu Kaisho,Takashi Tanaka,Makoto Matsumoto,Megumi Yamakami,Hiroko Omori,Masahiro Yamamoto,Tamotsu Yoshimori,Shizuo Akira,Journal of Immunology,Vol. 179,No. 8,p. 5378-5386,2007年10月15日,研究論文(学術雑誌)
  • Salmonella-induced SipB-independent cell death requires Toll-like receptor-4 signalling via the adapter proteins Tram and Trif,Pamela Cook,Sabine Tötemeyer,Catherine Stevenson,Katherine A. Fitzgerald,Masahiro Yamamoto,Shizuo Akira,Duncan J. Maskell,Clare E. Bryant,Immunology,Vol. 122,No. 2,p. 222-229,2007年10月,研究論文(学術雑誌)
  • Role for MyD88-independent, TRIF pathway in lipid A/TLR4-induced endotoxin tolerance,Subhra K. Biswas,Pradeep Bist,Manprit Kaur Dhillon,Tasneem Kajiji,Carlos Del Fresno,Masahiro Yamamoto,Eduardo Lopez-Collazo,Shizuo Akira,Vinay Tergaonkar,Journal of Immunology,Vol. 179,No. 6,p. 4083-4092,2007年09月15日,研究論文(学術雑誌)
  • Essential role of IRAK-4 protein and its kinase activity in Toll-like receptor-mediated immune responses but not in TCR signaling,Tatsukata Kawagoe,Shintaro Sato,Andreas Jung,Masahiro Yamamoto,Kosuke Matsui,Hiroki Kato,Satoshi Uematsu,Osamu Takeuchi,Shizuo Akira,Journal of Experimental Medicine,Vol. 204,No. 5,p. 1013-1024,2007年05月,研究論文(学術雑誌)
  • Toll/IL-1 receptor domain-containing adaptor inducing IFN-β (TRIF)-mediated signaling contributes to innate immune responses in the lung during Escherichia coli pneumonia,Samithamby Jeyaseelan,Scott K. Young,Michael B. Fessler,Yuhong Liu,Kenneth C. Malcolm,Masahiro Yamamoto,Shizuo Akira,G. Scott Worthen,Journal of Immunology,Vol. 178,No. 5,p. 3153-3160,2007年03月01日,研究論文(学術雑誌)
  • A role of Toll-IL-1 receptor domain-containing adaptor-inducing IFN-β in the host response to Pseudomonas aeruginosa lung infection in mice,Melanie R. Power,Bo Li,Masahiro Yamamoto,Shizuo Akira,Tong Jun Lin,Journal of Immunology,Vol. 178,No. 5,p. 3170-3176,2007年03月01日,研究論文(学術雑誌)
  • NF-κB activation by the Toll-IL-1 receptor domain protein MyD88 adapter-like is regulated by caspase-1,Sinead M. Miggin,Eva Pålsson-McDermott,Aisling Dunne,Caroline Jefferies,Emmanuel Pinteaux,Kathy Banahan,Caroline Murphy,Paul Moynagh,Masahiro Yamamoto,Shizuo Akira,Nancy Rothwell,Douglas Golenbock,Katherine A. Fitzgerald,Luke A.J. O'Neill,Proceedings of the National Academy of Sciences of the United States of America,Vol. 104,No. 9,p. 3372-3377,2007年02月27日,研究論文(学術雑誌)
  • Pathological role of Toll-like receptor signaling in cerebral malaria,Cevayir Coban,Satoshi Uematsu,Nobuko Arisue,Shintaro Sato,Masahiro Yamamoto,Taro Kawai,Osamu Takeuchi,Hajime Hisaeda,Toshihiro Horii,Shizuo Akira,International Immunology,Vol. 19,No. 1,p. 67-79,2007年01月,研究論文(学術雑誌)
  • VP1686, a Vibrio type III secretion protein, induces Toll-like receptor-independent apoptosis in macrophage through NF-κB inhibition,Rabindra N. Bhattacharjee,Kwon Sam Park,Yutaro Kumagai,Kazuhisa Okada,Masahiro Yamamoto,Satoshi Uematsu,Kosuke Matsui,Himanshu Kumar,Taro Kawai,Tetsuya Iida,Takeshi Honda,Osamu Takeuchi,Shizuo Akira,Journal of Biological Chemistry,Vol. 281,No. 48,p. 36897-36904,2006年12月01日,研究論文(学術雑誌)
  • TLR-dependent induction of IFN-β mediates host defense against Trypanosoma cruzi,Ritsuko Koga,Shinjiro Hamano,Hirotaka Kuwata,Koji Atarashi,Masahiro Ogawa,Hajime Hisaeda,Masahiro Yamamoto,Shizuo Akira,Kunisuke Himeno,Makoto Matsumoto,Kiyoshi Takeda,Journal of Immunology,Vol. 177,No. 10,p. 7059-7066,2006年11月15日,研究論文(学術雑誌)
  • The myeloid differentiation factor 88 is dispensable for the development of a delayed host response to Pseudomonas aeruginosa lung infection in mice,M. R. Power,J. S. Marshall,M. Yamamoto,S. Akira,T. J. Lin,Clinical and Experimental Immunology,Vol. 146,No. 2,p. 323-329,2006年11月,研究論文(学術雑誌)
  • TAK1 is indispensable for development of T cells and prevention of colitis by the generation of regulatory T cells,Shintaro Sato,Hideki Sanjo,Tohru Tsujimura,Jun Ninomiya-Tsuji,Masahiro Yamamoto,Taro Kawai,Osamu Takeuchi,Shizuo Akira,International Immunology,Vol. 18,No. 10,p. 1405-1411,2006年10月,研究論文(学術雑誌)
  • Detection of pathogenic intestinal bacteria by Toll-like receptor 5 on intestinal CD11c<sup>+</sup> lamina propria cells,Satoshi Uematsu,Myoung Ho Jang,Nicolas Chevrier,Zijin Guo,Yutaro Kumagai,Masahiro Yamamoto,Hiroki Kato,Nagako Sougawa,Hidenori Matsui,Hirotaka Kuwata,Hiroaki Hemmi,Cevayir Coban,Taro Kawai,Ken J. Ishii,Osamu Takeuchi,Masayuki Miyasaka,Kiyoshi Takeda,Shizuo Akira,Nature Immunology,Vol. 7,No. 8,p. 868-874,2006年08月,研究論文(学術雑誌)
  • Essential role of IPS-1 in innate immune responses against RNA viruses,Himanshu Kumar,Taro Kawai,Hiroki Kato,Shintaro Sato,Ken Takahashi,Cevayir Coban,Masahiro Yamamoto,Satoshi Uematsu,Ken J. Ishii,Osamu Takeuchi,Shizuo Akira,Journal of Experimental Medicine,Vol. 203,No. 7,p. 1795-1803,2006年07月10日,研究論文(学術雑誌)
  • Toll/IL-1R domain-containing adaptor protein (TIRAP) is a critical mediator of antibacterial defense in the lung against Klebsiella pneumoniae but not Pseudomonas aeruginosa,Samithamby Jeyaseelan,Scott K. Young,Masahiro Yamamoto,Patrick G. Arndt,Shizuo Akira,Jay K. Kolls,G. Scott Worthen,Journal of Immunology,Vol. 177,No. 1,p. 538-547,2006年07月01日,研究論文(学術雑誌)
  • Negative regulation of interferon-regulatory factor 3-dependent innate antiviral response by the prolyl isomerase Pin1,Tatsuya Saitoh,Adrian Tun-Kyi,Akihide Ryo,Masahiro Yamamoto,Greg Finn,Takashi Fujita,Shizuo Akira,Naoki Yamamoto,Kun Ping Lu,Shoji Yamaoka,Nature Immunology,Vol. 7,No. 6,p. 598-605,2006年06月,研究論文(学術雑誌)
  • Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses,Hiroki Kato,Osamu Takeuchi,Shintaro Sato,Mitsutoshi Yoneyama,Masahiro Yamamoto,Kosuke Matsui,Satoshi Uematsu,Andreas Jung,Taro Kawai,Ken J. Ishii,Osamu Yamaguchi,Kinya Otsu,Tohru Tsujimura,Chang Sung Koh,Caetano Reis E Sousa,Yoshiharu Matsuura,Takashi Fujita,Shizuo Akira,Nature,Vol. 441,No. 1,p. 101-105,2006年05月04日,研究論文(学術雑誌)
  • "Endogenous adjuvant" activity of the RNA components of lupus auto antigens Sm/RNP and Ro 60,Kindra M. Kelly,Haoyang Zhuang,Dina C. Nacionales,Philip O. Scumpia,Robert Lyons,Jun Akaogi,Pui Lee,Bryan Williams,Masahiro Yamamoto,Shizuo Akira,Minoru Satoh,Westley H. Reeves,Arthritis and Rheumatism,Vol. 54,No. 5,p. 1557-1567,2006年05月,研究論文(学術雑誌)
  • Erratum: A toll-like receptor-independent antiviral response induced by double-stranded B-form DNA (Nature Immunology (2005) vol. 7 (40-48)),Ken J. Ishii,Cevayir Coban,Hiroki Kato,Ken Takahashi,Yuichi Torii,Fumihiko Takeshita,Holger Ludwig,Gerd Sutter,Koichi Suzuki,Hiroaki Hemmi,Shintaro Sato,Masahiro Yamamoto,Satoshi Uematsu,Taro Kawai,Osamu Takeuchi,Shizuo Akira,Nature Immunology,Vol. 7,No. 4,2006年04月,研究論文(学術雑誌)
  • The myristoylation of TRIF-related adaptor molecule is essential for Toll-like receptor 4 signal transduction,Daniel C. Rowe,Anne F. McGettrick,Eicke Latz,Brian G. Monks,Nicholas J. Gay,Masahiro Yamamoto,Shizuo Akira,Luke A. O'Neill,Katherine A. Fitzgerald,Douglas T. Golenbock,Proceedings of the National Academy of Sciences of the United States of America,Vol. 103,No. 16,p. 6299-6304,2006年04月,研究論文(学術雑誌)
  • Mechanism of pathogen-specific TLR4 activation in the mucosa: Fimbriae, recognition receptors and adaptor protein selection,Hans Fischer,Masahiro Yamamoto,Shizuo Akira,Bruce Beutler,Catharina Svanborg,European Journal of Immunology,Vol. 36,No. 2,p. 267-277,2006年02月,研究論文(学術雑誌)
  • A toll-like receptor-independent antiviral response induced by double-stranded B-form DNA,Ken J. Ishii,Cevayir Coban,Hiroki Kato,Ken Takahashi,Yuichi Torii,Fumihiko Takeshita,Holger Ludwig,Gerd Sutter,Koichi Suzuki,Hiroaki Hemmi,Shintaro Sato,Masahiro Yamamoto,Satoshi Uematsu,Taro Kawai,Osamu Takeuchi,Shizuo Akira,Nature Immunology,Vol. 7,No. 1,p. 40-48,2006年01月,研究論文(学術雑誌)
  • BS69, a specific adaptor in the latent membrane protein 1-mediated c-Jun N-terminal kinase pathway,Jun Wan,Wei Zhang,Liming Wu,Ting Bai,Mingjie Zhang,Kwok Wai Lo,Yiu Ioon Chui,Yan Cui,Qian Tao,Masahiro Yamamoto,Shizuo Akira,Zhenguo Wu,Molecular and Cellular Biology,Vol. 26,No. 2,p. 448-456,2006年01月,研究論文(学術雑誌)
  • Toll-IL-1 receptor domain-containing adaptor protein is critical for early lung immune responses against Escherichia coli lipopolysaccharide and viable Escherichia coli,Samithamby Jeyaseelan,Rizwan Manzer,Scott K. Young,Masahiro Yamamoto,Shizuo Akira,Robert J. Mason,G. Scott Worthen,Journal of Immunology,Vol. 175,No. 11,p. 7484-7495,2005年12月01日,研究論文(学術雑誌)
  • Essential function for the kinase TAK1 in innate and adaptive immune responses,Shintaro Sato,Hideki Sanjo,Kiyoshi Takeda,Jun Ninomiya-Tsuji,Masahiro Yamamoto,Taro Kawai,Kunihiro Matsumoto,Osamu Takeuchi,Shizuo Akira,Nature Immunology,Vol. 6,No. 11,p. 1087-1095,2005年11月,研究論文(学術雑誌)
  • The RNA helicase Lgp2 inhibits TLR-independent sensing of viral replication by retinoic acid-inducible gene-I,Simon Rothenfusser,Nadege Goutagny,Gary DiPerna,Mei Gong,Brian G. Monks,Annett Schoenemeyer,Masahiro Yamamoto,Shizuo Akira,Katherine A. Fitzgerald,Journal of Immunology,Vol. 175,No. 8,p. 5260-5268,2005年10月15日,研究論文(学術雑誌)
  • Priming effect of lipopolysaccharide on acetyl-coenzyme A: Lyso-platelet-activating factor acetyltransferase is MyD88 and TRIF independent,Hideo Shindou,Satoshi Ishii,Masahiro Yamamoto,Kiyoshi Takeda,Shizuo Akira,Takao Shimizu,Journal of Immunology,Vol. 175,No. 2,p. 1177-1183,2005年07月15日,研究論文(学術雑誌)
  • Cell type-specific involvement of RIG-I in antiviral response,Hiroki Kato,Shintaro Sato,Mitsutoshi Yoneyama,Masahiro Yamamoto,Satoshi Uematsu,Kosuke Matsui,Tohru Tsujimura,Kiyoshi Takeda,Takashi Fujita,Osamu Takeuchi,Shizuo Akira,Immunity,Vol. 23,No. 1,p. 19-28,2005年07月,研究論文(学術雑誌)
  • Induction of CXCL5 during inflammation in the rodent lung involves activation of alveolar epithelium,Samithamby Jeyaseelan,Rizwan Manzer,Scott K. Young,Masahiro Yamamoto,Shizuo Akira,Robert J. Mason,G. Scott Worthen,American Journal of Respiratory Cell and Molecular Biology,Vol. 32,No. 6,p. 531-539,2005年06月,研究論文(学術雑誌)
  • Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-α induction,Satoshi Uematsu,Shintaro Sato,Masahiro Yamamoto,Tomonori Hirotani,Hiroki Kato,Fumihiko Takeshita,Michiyuki Matsuda,Cevayir Coban,Ken J. Ishii,Taro Kawai,Osamu Takeuchi,Shizuo Akira,Journal of Experimental Medicine,Vol. 201,No. 6,p. 915-923,2005年03月21日,研究論文(学術雑誌)
  • The nuclear IκB protein IκBNS selectively inhibits lipopolysaccharide-induced IL-6 production in macrophages of the colonic lamina propria,Tomonori Hirotani,Pui Y. Lee,Hirotaka Kuwata,Masahiro Yamamoto,Makoto Matsumoto,Ichiro Kawase,Shizuo Akira,Kiyoshi Takeda,Journal of Immunology,Vol. 174,No. 6,p. 3650-3657,2005年03月15日,研究論文(学術雑誌)
  • Regulation of lipopolysaccharide-inducible genes by MyD88 and Toll/IL-1 domain containing adaptor inducing IFN-β,Tomonori Hirotani,Masahiro Yamamoto,Yutaro Kumagai,Satoshi Uematsu,Ichiro Kawase,Osamu Takeuchi,Shizuo Akira,Biochemical and Biophysical Research Communications,Vol. 328,No. 2,p. 383-392,2005年03月11日,研究論文(学術雑誌)
  • A20 is a negative regulator of IFN regulatory factor 3 signaling,Tatsuya Saitoh,Masahiro Yamamoto,Makoto Miyagishi,Kazunari Taira,Makoto Nakanishi,Takashi Fujita,Shizuo Akira,Naoki Yamamoto,Shoji Yamaoka,Journal of Immunology,Vol. 174,No. 3,p. 1507-1512,2005年02月01日,研究論文(学術雑誌)
  • Spontaneous ocular surface inflammation and goblet cell disappearance in IκBζ gene-disrupted mice,Mayumi Ueta,Junji Hamuro,Masahiro Yamamoto,Kazuhiro Kaseda,Shizuo Akira,Shigeru Kinoshita,Investigative Ophthalmology and Visual Science,Vol. 46,No. 2,p. 579-588,2005年02月,研究論文(学術雑誌)
  • Roles of Stat3 and ERK in G-CSF signaling.,Kenjirou Kamezaki,Kazuya Shimoda,Akihiko Numata,Takashi Haro,Haruko Kakumitsu,Masumi Yoshie,Masahiro Yamamoto,Kiyoshi Takeda,Tadashi Matsuda,Shizuo Akira,Katsuhiro Ogawa,Mine Harada,Stem cells (Dayton, Ohio),Vol. 23,No. 2,p. 252-63,2005年02月,研究論文(学術雑誌)
  • Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin,Cevayir Coban,Ken J. Ishii,Taro Kawai,Hiroaki Hemmi,Shintaro Sato,Satoshi Uematsu,Masahiro Yamamoto,Osamu Takeuchi,Sawako Itagaki,Nirbhay Kumar,Toshihiro Horii,Shizuo Akira,Journal of Experimental Medicine,Vol. 201,No. 1,p. 19-25,2005年01月03日,研究論文(学術雑誌)
  • Mechanisms of innate immune responses mediated by Toll-like receptors,Masahiro Yamamoto,Shizuo Akira,Clinical and Applied Immunology Reviews,Vol. 5,No. 3,p. 167-183,2005年,研究論文(学術雑誌)
  • TIR domain-containing adaptors regulate TLR signaling pathways,Masahiro Yamamoto,Shizuo Akira,Advances in Experimental Medicine and Biology,Vol. 560,p. 1-9,2005年,研究論文(国際会議プロシーディングス)
  • IFN regulatory factor 3-dependent induction of type I IFNs by intracellular bacteria is mediated by a TLR- and Nod2-independent mechanism,Silvia Stockinger,Benjamin Reutterer,Barbara Schaljo,Carola Schellack,Sylvia Brunner,Tilo Materna,Masahiro Yamamoto,Shizuo Akira,Tadatsugu Taniguchi,Peter J. Murray,Mathias Müller,Thomas Decker,Journal of Immunology,Vol. 173,No. 12,p. 7416-7425,2004年12月15日,研究論文(学術雑誌)
  • TIR domain--containing adaptors regulate TLR-mediated signaling pathways,Masahiro Yamamoto,Shizuo Akira,Nippon rinsho. Japanese journal of clinical medicine,Vol. 62,No. 12,p. 2197-2203,2004年12月
  • ASC is essential for LPS-induced activation of procaspase-1 independently of TLR-associated signal adaptor molecules,Masatatsu Yamamoto,Katsuyuki Yaginuma,Hiroko Tsutsui,Junji Sagara,Xin Guan,Ekihiro Seki,Koubun Yasuda,Masahiro Yamamoto,Shizuo Akira,Kenji Nakanishi,Tetsuo Noda,Shun'ichiro Taniguchi,Genes to Cells,Vol. 9,No. 11,p. 1055-1067,2004年11月,研究論文(学術雑誌)
  • Activation of TBK1 and IKKε kinases by vesicular stomatitis virus infection and the role of viral ribonucleoprotein in the development of interferon antiviral immunity,Benjamin R. TenOever,Sonia Sharma,Wen Zou,Qiang Sun,Nathalie Grandvaux,Ilkka Julkunen,Hiroaki Hemmi,M. Yamamoto,Shizuo Akira,Wen Chen Yeh,Rongtuan Lin,John Hiscott,Journal of Virology,Vol. 78,No. 19,p. 10636-10649,2004年10月,研究論文(学術雑誌)
  • Interferon-α induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6,Taro Kawai,Shintaro Sato,Ken J. Ishii,Cevayir Coban,Hiroaki Hemmi,Masahiro Yamamoto,Kenta Terai,Michiyuki Matsuda,Jun Ichiro Inoue,Satoshi Uematsu,Osamu Takeuchi,Shizuo Akira,Nature Immunology,Vol. 5,No. 10,p. 1061-1068,2004年10月,研究論文(学術雑誌)
  • MyD88 but not TRIF is essential for osteoclastogenesis induced by lipopolysaccharide, diacyl lipopeptide, and IL-1α,Nobuaki Sato,Naoyuki Takahashi,Koji Suda,Midori Nakamura,Mariko Yamaki,Tadashi Ninomiya,Yasuhiro Kobayashi,Haruhiko Takada,Kenichiro Shibata,Masahiro Yamamoto,Kiyoshi Takeda,Shizuo Akira,Toshihide Noguchi,Nobuyuki Udagawa,Journal of Experimental Medicine,Vol. 200,No. 5,p. 601-611,2004年09月06日,研究論文(学術雑誌)
  • The roles of two IκB kinase-related kinases in lipopolysaccharide and double stranded RNA signaling and viral infection,Hiroaki Hemmi,Osamu Takeuchi,Shintaro Sato,Masahiro Yamamoto,Tsuneyasu Kaisho,Hideki Sanjo,Taro Kawai,Katsuaki Hoshino,Kiyoshi Takeda,Shizuo Akira,Journal of Experimental Medicine,Vol. 199,No. 12,p. 1641-1650,2004年06月21日,研究論文(学術雑誌)
  • TIR domain-containing adaptors define the specificity of TLR signaling,Masahiro Yamamoto,Kiyoshi Takeda,Shizuo Akira,Molecular Immunology,Vol. 40,No. 12,p. 861-868,2004年02月,研究論文(学術雑誌)
  • IL-10-inducible Bcl-3 negatively regulates LPS-induced TNF-α production in macrophages,Hirotaka Kuwata,Yasuyuki Watanabe,Hiroyuki Miyoshi,Masahiro Yamamoto,Tsuneyasu Kaisho,Kiyoshi Takeda,Shizuo Akira,Blood,Vol. 102,No. 12,p. 4123-4129,2003年12月01日,研究論文(学術雑誌)
  • Toll/IL-1 receptor domain-containing adaptor inducing IFN-β (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-κB and IFN-regulatory factor-3, in the toll-like receptor signaling,Shintaro Sato,Masanaka Sugiyama,Masahiro Yamamoto,Yasuyuki Watanabe,Taro Kawai,Kiyoshi Takeda,Shizuo Akira,Journal of Immunology,Vol. 171,No. 8,p. 4304-4310,2003年10月15日,研究論文(学術雑誌)
  • Role of adapters in Toll-like receptor signalling,S. Akira,M. Yamamoto,K. Takeda,Biochemical Society Transactions,Vol. 31,No. 3,p. 637-642,2003年06月,研究論文(国際会議プロシーディングス)

MISC

  • IRAK-1はTLR7とTLR9を解するIFN-α産生に必須の役割を果たす,植松智,佐藤慎太郎,山本雅裕,加藤博己,石井健,河合太郎,竹内理,竹内理,審良静男,審良静男,日本免疫学会総会・学術集会記録,Vol. 35,2005年
  • RIG-I欠損マウスの作成および解析,加藤博己,佐藤慎太郎,山本雅裕,松井孝介,植松智,竹田潔,竹内理,審良静男,日本免疫学会総会・学術集会記録,Vol. 34,2004年
  • Plasmacytoid DCにおけるToll-like receptor 9によるtype Iインターフェロンの誘導機構,植松智,佐藤慎太郎,山本雅裕,加藤博己,石井健,河合太郎,竹内理,審良静男,日本免疫学会総会・学術集会記録,Vol. 34,2004年
  • Toll様受容体を介したI型IFN産生誘導のメカニズム,河合太郎,佐藤慎太郎,石井健,COBAN C,辺見弘明,山本雅裕,植松智,竹内理,審良静男,日本免疫学会総会・学術集会記録,Vol. 34,2004年
  • TIRAP/MalはTLR4シグナルだけでなく,TLR2シグナルにも関わっている,山本雅裕,佐藤慎太郎,辺見弘明,山条秀樹,植松智,改正恒康,星野克明,竹田潔,審良静男,日本免疫学会総会・学術集会記録,Vol. 32,2002年

特許・実用新案・意匠

  • TLRリガンド及びIL-1応答障害性モデル動物,山本 雅裕,審良 静男,特許第4236549号,2004-124758,出願日:2004年04月,登録日:2005年05月
  • エンドトキシン不応答性モデル動物,山本 雅裕,審良 静男,2003-338013,出願日:2003年09月

受賞

  • 野本賞,日本微生物学連盟,2020年09月
  • 第67回 小泉賞,日本寄生虫学会,2020年05月
  • 第15回 日本学術振興会賞,山本 雅裕,日本学術振興会,2019年02月
  • 第15回(平成30年度)日本学術振興会賞,2019年02月
  • 第二回 日本医療研究開発機構AMED理事長賞,山本 雅裕,内閣府,2018年12月
  • 第2回日本医療研究開発大賞 AMED理事長賞,2018年12月
  • Highly Cited Researchers 2017,山本 雅裕,Clarivate Analytics,2017年12月
  • Highly Cited Researchers 2016,山本 雅裕,Clarivate Analytics(旧トムソン・ロイター IP&Science),2016年11月
  • 科学技術分野の文部科学大臣 表彰 若手科学者,山本雅裕,文部科学省,2011年04月
  • 科学技術分野の文部科学大臣 表彰若手科学者,文部科学省,2011年04月
  • 第2回 日本免疫学会研究奨励賞,日本免疫学会,2007年12月
  • 日本免疫学会研究奨励賞,山本雅裕,日本免疫学会,2007年11月
  • 山村賞,山本雅裕,大阪大学大学院医学系研究科,2006年03月

講演・口頭発表等

  • 肝臓期マラリア原虫の分化を制御する宿主因子の同定,山本 雅裕,第72回日本細菌学会九州支部総会 第56回日本ウイルス学会九州支部総会,2019年09月
  • Role of CXCR4 in liver stage Plasmodium development,Masahiro Yamamoto,The 18th Awaji International Forum on Infection and Immunity,2019年09月
  • 常在グラム陰性細菌に対するCaspase-11インフラマソームの制御機構,山本 雅裕,第84回日本インターフェロン・サイトカイン学会学術集会,2019年08月
  • 肝臓期マラリアの分化に関与する宿主因子の同定,山本 雅裕,第27回分子寄生虫学ワークショップ/第17回分子寄生虫・マラリア研究フォーラム合同大会,2019年08月
  • Molecular basis of Toxoplasma PV membrane targeting by Irgb6,Masahiro Yamamoto,The XVth International Toxoplasma Congress,2019年06月
  • Cell-intrinsic host defense and microbial counterdefense,Masahiro Yamamoto,International Molecular Immunology & Immunogenetics congress,2019年04月
  • Toxoplasma GRA15-dependent suppression of IFN-gamma-induced anti-parasitic response,Masahiro Yamamoto,23th Annual Woods Hole ImmunoParasitology Conference,2019年04月
  • 病原性寄生虫トキソプラズマと宿主免疫の攻防,山本 雅裕,第1回 日本医学会連合Rising Starリトリート,2019年03月
  • トキソプラズマの寄生虫免疫学から導かれた意外な創薬ターゲット,山本 雅裕,新興・再興感染症制御プロジェクト 合同シンポジウム,2019年03月
  • Targeted disruption of IFN-γ-induced IDO1-dependent anti-parasitic response in human cells by Toxoplasma effector TgIST,Masahiro Yamamoto,The 3rd Asian Congress of Protistology & 10th Asian Conference of Ciliate Biology & 2nd International Symposium on Biodiversity and Evolution of Protozoa,2018年11月
  • トキソプラズマの宿主免疫返り討ち戦法について,山本雅裕,第26回分子寄生虫学ワークショップ/第16回分子寄生虫・マラリア研究フォーラム合同大会,2018年09月
  • Role of cell-intrinsic and innate immunity by interferon-inducible GTPases,Masahiro Yamamoto,The 10th Japanese-German Immunology Workshop,2018年09月
  • Host cell-intrinsic host defense and counter defenses against Toxoplasma,Masahiro Yamamoto,ICOPA2018 Biology and interaction of host/cell and Toxoplasma gondii infection,2018年08月
  • IFNγによる宿主免疫系におけるオートファジー関連分子群の非標準的役割,山本雅裕,日本インターフェロン・サイトカイン学会 シンポジウム2,2018年07月
  • 感染防御免疫系におけるATG8ファミリー分子群の役割,山本雅裕,千里ライフサイエンスセミナー M2 オートファジーと疾患,2018年06月
  • Essential role of ATG proteins in cell-autonomous innate immunity to vacuolar pathogens,Masahiro Yamamoto,15th International Conference on Innate Immunity,2018年06月
  • 肝臓機マラリア原虫の文化に重要な宿主因子の探索,山本雅裕,第70回日本衛星動物学会大会,2018年05月
  • Role of Atg8 in the regulation of NLRP3 inflammasome-mediated pyroptosis,Masahiro Yamamoto,Australia-Japan Meeting on Cell Death,2018年05月
  • Suppression of human IFN-γ-mediated anti-parasitic cell-autonomous immunity by a Toxoplasma effector,Masahiro Yamamoto,Intrisic Defenses and Counterdefenses Keystone Symposia,2018年03月
  • A family member of phospholipase C is required for CD8 T cell-mediated anti-Toxoplasma host defense,Masahiro Yamamoto,WHIP 2018 22th Annual Woods Hole ImmunoParasitology Conference,2018年03月
  • Critical roles of GABARAPs on interferon-mediated cell-autonomous immune responses against T. gondii infection,Miwa Sasai, Naoya Sakaguchi, Ji Su Ma, Youngae Lee, Hironori Bando, Shizuo Akira, Masahiro Yamamoto,第46回 日本免疫学会学術集会,2017年12月
  • PLCβ plays an important role in CD8 T cell-mediated host defense against Toxoplasma gondii,Ji Su Ma, Miwa Sasai, Youngae Lee, Naoya Sakaguchi, Hironori Bando, Masahiro Yamamoto,第46回 日本免疫学会学術集会,2017年12月
  • Role of GABARAP subfamily in the regulation of non-canonical inflammasome activation,Naoya Sakaguchi, Ji Su Ma, Youngae Lee, Hironori Bando, Miwa Sasai, Masahiro Yamamoto,第46回 日本免疫学会学術集会,2017年12月
  • Immunoparasitology of Toxoplasma gondii,Masahiro Yamamoto,The 2nd Annual International Conference and Exhibition on Indonesian Medical Education and Research Institute(IMERI) 2017,2017年12月
  • A mechanism of interferon-γ-induced anti-Toxoplasma gondii host defense,Masahiro Yamamoto,The 7th International Symposium on Parasitology,2017年10月
  • The Mammalian Atg8 Gabarap Subfamily Play a Non-Redundant Key Role in IFN-γ-Inducible GTPase-Dependent Host Defense Against Vacuolar Pathogens,Miwa Sasai, Naoya Sakaguchi, Ji SuMa, Youngae Lee, Hironori Bando, Masahiro Yamamoto,第16回 あわじしま感染症・免疫フォーラム,2017年09月
  • Atg8ファミリーのインターフェロン誘導性自然免疫における役割について,山本 雅裕, 笹井 美和, 坂口 直哉, 馬 知秀,The 3rd Annual Meeting of Japanese Society of Osteoimmunology 2017 ISHIGAKI,2017年06月
  • GABARAPs are required for the LC3-Independent antimicrobial host defense through cytosolic distribution of Interferon-Inducible GTPases,Miwa Sasai, Masahiro Yamamoto,8th International symposium on Autophagy,2017年05月
  • GABARAPs are required for LC3s-independent anti-Toxoplasma gondii host defense through cytosolic distribution of interferon-inducible GTPases,Masahiro Yamamoto,Toxo-14 (The Toxoplasma gondii research community biennial meeting 2017),2017年05月
  • Critical role of GABARAP Atg8 subfamily in IFN-γ-induced cell-autonomous immunity to Toxoplasma gondii,Masahiro Yamamoto,21th Annual Woods Hole ImmunoParasitology Conference,2017年04月
  • PLCβ4 plays an important role in CD8 T cell-mediated host defense against Toxoplasma gondii,Ji Su Ma, Miwa Sasai,Youngae Lee,Hironori Bando, and Masahiro Yamamoto,第10回 寄生虫感染免疫研究会,2017年02月
  • Essential role of Gate-16 in anti-Toxoplasma gondii immune response,Miwa Sasai, Ji Su Ma, Youngae Lee, Hironori Bando, Masahiro Yamamoto,第10回 寄生虫感染免疫研究会,2017年02月
  • Interferon-induced activation of cell-autonomous immunity against vacuolar pathogens,Masahiro Yamamoto,The 45th Annual meeting of the Japanese Society for Immunology,2016年12月
  • The Atg8 family members play a critical role in non-autophagic cell-autonomous immunity to vacuolar pathogens,Miwa Sasai, Naoya Sakaguchi, Masahiro Yamamoto,Keystome symposia,2016年12月
  • A mechanism for interferon-γ-induced ubiquitin decoration of Toxoplasma gondii parasitophorous vacuoles,Youngae Lee, Miwa Sasai, Ji Su Ma, Naoya Sakaguchi, Hironori Bando, Ariel Pradipta, and Masahiro Yamamoto,Forum Cheju18 Korea-Japan Parasitologists’Seminar,2016年10月
  • Mechanism of IFN-γ-inducible cell-autonomous immunity to intracellular pathogens,山本 雅裕,Awaji Yumebutai International Conference Center on Awaji Island,2016年09月
  • インターフェロンγによる細胞内寄生性病原体の排除機構,山本 雅裕,第81回日本インターフェロン・サイトカイン学会学術集会,2016年05月
  • ヒト細胞におけるIFNγ依存的な抗トキソプラズマ応答にはIDO2ではなくIDO1が重要な役割を果たす,伴戸 寛徳、笹井 美和、馬 知秀、李 英愛、坂口 直哉、山本 雅裕,第85回 日本寄生虫学会大会,2016年03月
  • オートファジーアダプター分子p62はインターフェロンγ誘導性のトキソプラズマの寄生胞抗原の提示に特異的に関与する,山本雅裕、李栄愛、笹井美和、馬知秀、伴戸博徳、坂口直哉,第85回 日本寄生虫学会大会,2016年03月
  • p62/Sqstm1 plays a specific role in CD8+ T cell activation by antigen-presenting cells after IFN-γ-induced disruption of the parasitophorous vacuoles of Toxoplasma gondii,Masahiro Yamamoto, Youngae Lee,第9回 寄生虫感染免疫研究会,2016年02月
  • FN-γ-inducible cell-autonomous immunity to intracellular pathogens,Masahiro Yamamoto,The 7th International Symposium of IFReC,2016年01月
  • インターフェロンγ誘導性GTPaseによるトキソプラズマ寄生胞の破壊制御機構,山本 雅裕,第38回日本分子生物学会年会、第88回日本生化学会大会 合同大会,2015年12月
  • p62 plays a specific role in IFN-g-induced presentation of a Toxoplasma vacuolar antigen,Youngae Lee, Miwa Sasai, Ji Su Ma, Naoya Sakaguchi, Jun Ohshima, Hironori Bando, Tatsuya Saitoh, Shizuo Akira, and Masahiro Yamamoto,The 44th Annual Meeting of The Japanese Society for Immunology,2015年11月
  • RabGDIα is a negative regulator of interferon-γ-inducible GTPase-dependent cell-autonomous immunity to Toxoplasma gondii,Miwa Sasai, Jun Ohshima, Ji Su Ma, Youngae Lee, Kiyoshi Takeda, Masahiro Yamamoto,The 44th Annual Meeting of The Japanese Society for Immunology,2015年11月
  • p62 plays a specific role in IFN-g-induced presentation of a Toxoplasma vacuolar antigen,Youngae Lee, Miwa Sasai, Ji Su Ma, Naoya Sakaguchi, Jun Ohshima, Hironori Bando, Tatsuya Saitoh, Shizuo Akira, and Masahiro Yamamoto,Forum Cheju17,2015年11月
  • Selective and strain-specific NFAT4 activation by the Toxoplasma gondii polymorphic dense granule protein GRA6,Ji Su Ma, Miwa Sasai, Jun Ohshima, Youngae Lee, Hironori Bando, Kiyoshi Takeda, and Masahiro Yamamoto,Forum Cheju17,2015年11月
  • トキソプラズマ病原性因子による免疫ハイジャック機構,Yamamoto M,第158回日本獣医学会学術集会 シンポジウム,2015年09月
  • 宿主免疫系によるトキソプラズマ原虫の排除機構とその破綻の分子機構,Yamamoto M,第27回 日本比較免疫学会学術集会 シンポジウム,2015年08月
  • Positive and Negative Regulation of IFN-γ-inducible GTPase-dependent cell-autonomous immunity to Toxoplasma gondii,Yamamoto M,RIKEN IMS-JSI International Symposium on Immunology 2015,2015年06月
  • 肝臓期マラリア原虫を標的とした新規抗マラリア薬の開発,伴戸 寛徳, 笹井 美和, 馬 知秀, 大嶋 淳, 李 英愛, 山本 雅裕,第84回日本寄生虫学会大会,2015年03月
  • トキソプラズマ原虫の多型濃縮顆粒タンパク質GRA6による選択的NFAT4の活性化について,馬 知秀, 笹井 美和, 大嶋 淳, 李 英愛, 伴戸 寛徳, 竹田 潔, 山本 雅裕,第84回日本寄生虫学会大会,2015年03月
  • トキソプラズマ病原性因子GRA6による宿主免疫乗っ取り機構,山本 雅裕,感染症国際研究センター/共同研究拠点 若手ジョイントシンポジウム,2015年02月
  • RabGDIα is a negative regulator of interferon-γ-inducible GTPase-dependent cell-autonomous host defense against Toxoplasma gondii,Jun Ohshima, Miwa Sasai, Ji Su Ma, Youngae Lee, Hironori Bando, Kiyoshi Takeda, Masahiro Yamamoto,第8回 寄生虫感染免疫研究会,2015年02月
  • Selective and strain-specific NFAT4 activation by the Toxoplasma gondii polymorphic dense granule protein GRA6,Ji Su Ma, Miwa Sasai, Jun Ohshima, Youngae Lee, Hironori Bando, Kiyoshi Takeda, Masahiro Yamamoto,第8回 寄生虫感染免疫研究会,2015年02月
  • Toxoplasma gondii GRA6 selectively activates NFAT4 to induce chemokine CXCL2 and CCL2,Sasai M, Ma JiSu, Ohshima J, Lee Y, Takeda K, Yamamoto M.,日本免疫学会学術集会,2014年12月
  • Role of mouse autophagy proteins in IFN-γ-mediated cell-autonomous responses against Toxoplasma gondii.,Ohshima J, Sasai M, Ma JiSu, Lee Y, Takeda K, Yamamoto M.,日本免疫学会学術集会,2014年12月
  • Human ATG16L1 and GBPs are dispensable for IFN-γ–dependent anti–Toxoplasma gondii responses,Youngae Lee, Jun Ohshima, Miwa Sasai, Ji Su Ma, Masahiro Yamamoto.,日本免疫学会学術集会,2014年12月
  • インターフェロン-γ;誘導性 GTPaseによるトキソプラズマ原虫殺傷機構について,山本雅裕、大嶋淳、Lee Youngae、笹井美和,第87回日本生化学会大会,2014年10月
  • NFAT4 activation by the Toxoplasma gondii polymorphic effector protein GRA6 maximizes the parasite virulence in a strain-specific manner,Yamamoto M.,The 13th Awaji International Forum on Infection and Immunity,2014年09月
  • Identification of natural compounds that inhibit growth of intracellular pathogens.,Bui XT, Sasai M, Yamamoto M, Koburi T, and Nagai H,第13回あわじしま感染症・免疫フォー ラム,2014年09月
  • トキソプラズマ原虫の免疫寄生虫学,山本雅裕,第16回免疫サマースクール2014 in 小豆島,2014年07月
  • トキソプラズマ原虫と宿主の免疫学的攻防,Masahiro Yamamoto,平成26年度 遺伝子病制御研究所研究集会,2014年07月
  • Activation of host NFAT by a Toxoplasmagondii polymorphic dense granule protein plays an important role in virulence mediated by the local infection,Yamamoto M, Ma JS, Ohshima J, Sasai M,18th Annual Woods Hole ImmunoParasitology Conference,2014年04月
  • IFN-γ依存的抗トキソプラズマ応答におけるオートファジー蛋白質の役割,Yamamoto M, Oshima J, Su Ma J, Lee Y,第83回日本寄生虫学会大会,2014年03月
  • Selective and strain-specific NFAT4 activation by the Toxoplasma gondii polymorphic dense granule protein GRA6,Ji Su Ma, Miwa Sasai, Kiyoshi Takeda, Masahiro Yamamoto.,日本免疫学会総会学術大会,2013年12月
  • Toxoplasam gondii Poluymorphic Dense Granule Protein GRA6 Selectively and strain-spcific activates NFAT4.,Masahiro Yamamoto,TCUID2013,2013年11月
  • Roles of de-ubiquitinating enzymes on the propagation of HCV,Toru Okamoto, Yukari Sugiyama, Chikako Ono, Sayaka Aizawa, Pham Duc Ngoc, Takahisa Kohwaki, Eiji Hirooka, Takasuke Fukuhara, Masahiro Yamamoto, Yoshiharu Matsuura,International Symposium on Hepatitis C Virus and Related Viruses,2013年10月
  • A protozoan parasite Toxoplasma gondii manipulates host cell functions by effector molecules,Masahiro Yamamoto,The XIVth International Congress of Protistology,2013年08月
  • Immunological interface between host and a protozoan parasite Toxoplasma gondii,Masahiro Yamamoto,FORUM GRADUATE SCHOOLS INFECTION & IMMUNITY BIOLOGIE-MEDECINE,2013年06月
  • インターフェロンガンマ依存性の細胞内侵入病原体排除におけるオートファジー関連タンパク質の役割の解明,Jun Ooshima, Miwa Sasai, Masahiro Yamamot, Mikamo Hayashi,日本歯科保存学会春季学術大会,2013年06月

報道

  • マラリア予防に白血病治療薬が効果,NHK,2019年07月
  • マラリアが増える仕組み解明,読売新聞,2019年06月
  • C型肝炎ウイルス、薬剤耐性なく治療する化合物 阪大、アルツハイ マー病治療薬の候補の中に...トキソプラズマなども効果,産経新聞,2017年11月
  • 審良研で世界との熾烈な競争を経験、トキソプラズマと宿主の関係解明へ,日経バイオテク2月15日号「若手研究者の肖像」(第10回),2016年02月
  • トキソプラズマ『トロイの木馬』現象 原因タンパク質 確認,読売新聞,2014年09月
  • 「ミチをひらく」下,朝日新聞,2014年06月
  • 「ミチをひらく」上,朝日新聞,2014年06月

学術貢献

  • 新興・再興感染症制御プロジェクト 合同シンポジウム,AMED,2019年03月 ~
  • 第1回 日本医学会連合Rising Starリトリート,日本医学会連合,2019年03月 ~
  • The 3rd Asian Congress of Protistology & 10th Asian Conference of Ciliate Biology & 2nd International Symposium on Biodiversity and Evolution of Protozoa,Asian Committee of Protistologists,2018年11月 ~
  • 第26回分子寄生虫学ワークショップ/第16回分子寄生虫・マラリア研究フォーラム合同大会 特別企画・免疫,日本寄生虫学会,2018年09月 ~
  • The 10th Japanese-German Immunology Workshop. Session 3: Uniqueness in the Development and Function of Innate Immunity.,日独免疫学会議,2018年09月 ~

社会貢献

  • 大阪中学生サマー・セミナー,大阪中学生サマーセミナー協議会,2016年08月 ~
  • 第16回免疫サマースクール2014 in 小豆島,日本免疫学会,2014年07月 ~