顔写真

PHOTO

Omatsu Yoshiki
尾松　芳樹
Omatsu Yoshiki
尾松　芳樹
Institutional repository
Graduate School of Frontier Biosciences　Department of Frontier Biosciences, Associate Professor

keyword Hematology，Immunology

Institutional repository

Professional Memberships 2

  1. 日本骨免疫学会

  2. JAPANESE SOCIETY FOR IMMUNOLOGY

Research Areas 1

  1. Life sciences / Immunology /

Awards 1

  1. JSI Young Investigator Award

    OMATSU Yoshiki　Japanese Society for Immunology　2014/12

Papers 21

  1. Ebf3+ niche-derived CXCL12 is required for the localization and maintenance of hematopoietic stem cells

    Taichi Nakatani, Tatsuki Sugiyama, Yoshiki Omatsu, Hitomi Watanabe, Gen Kondoh, Takashi Nagasawa

    Nature Communications　2023/10/25　Research paper (scientific journal)

  2. Runx1 and Runx2 inhibit fibrotic conversion of cellular niches for hematopoietic stem cells

    Yoshiki Omatsu, Shota Aiba, Tomonori Maeta, Kei Higaki, Kazunari Aoki, Hitomi Watanabe, Gen Kondoh, Riko Nishimura, Shu Takeda, Ung-il Chung, Takashi Nagasawa

    Nature Communications　Vol. 13　No. 1　2022/12　Research paper (scientific journal)

    Publisher: Springer Science and Business Media LLC

  3. Stem cell niche-specific Ebf3 maintains the bone marrow cavity

    Masanari Seike, Yoshiki Omatsu, Hitomi Watanabe, Gen Kondoh, Takashi Nagasawa

    Genes and Development　Vol. 32　No. 5-6　p. 359-372　2018/03/01　Research paper (scientific journal)

    Publisher: Cold Spring Harbor Laboratory Press

  4. Foxc1 is a critical regulator of haematopoietic stem/progenitor cell niche formation

    Yoshiki Omatsu, Masanari Seike, Tatsuki Sugiyama, Tsutomu Kume, Takashi Nagasawa

    NATURE　Vol. 508　No. 7497　p. 536-+　2014/04　Research paper (scientific journal)

  5. The Essential Functions of Adipo-osteogenic Progenitors as the Hematopoietic Stem and Progenitor Cell Niche

    Yoshiki Omatsu, Tatsuki Sugiyama, Hiroshi Kohara, Gen Kondoh, Nobutaka Fujii, Kenji Kohno, Takashi Nagasawa

    IMMUNITY　Vol. 33　No. 3　p. 387-399　2010/09　Research paper (scientific journal)

  6. Universal fibroblasts across tissues can differentiate into niche cells for hematopoietic stem cells

    Kei Higaki, Shota Aiba, Takashi Shimoyama, Yoshiki Omatsu, Takashi Nagasawa

    Cell Reports　Vol. 44　No. 5　p. 115620-115620　2025/05　Research paper (scientific journal)

    Publisher: Elsevier BV

  7. Acute malaria suppresses the B lymphocytic niche in the bone marrow through the alteration of CXCL12-abundant reticular cells

    Michelle Sue Jann Lee, Julia Matsuo-Dapaah, Camila Del Rosario Zorrilla, Yoshiki Omatsu, Takashi Nagasawa, Shun Uemura, Atsushi Iwama, Ken J Ishii, Cevayir COBAN

    International Immunology　2024/03/02　Research paper (scientific journal)

  8. Cellular niches for hematopoietic stem cells in bone marrow under normal and malignant conditions

    Yoshiki Omatsu

    Inflammation and Regeneration　Vol. 43　No. 1　2023/02/21　Research paper (scientific journal)

    Publisher: Springer Science and Business Media LLC

  9. A multistate stem cell dynamics maintains homeostasis in mouse spermatogenesis

    Toshinori Nakagawa, David J. Jörg, Hitomi Watanabe, Seiya Mizuno, Seungmin Han, Tatsuro Ikeda, Yoshiki Omatsu, Keiko Nishimura, Miyako Fujita, Satoru Takahashi, Gen Kondoh, Benjamin D. Simons, Shosei Yoshida, Takashi Nagasawa

    Cell Reports　Vol. 37　No. 3　p. 109875-109875　2021/10　Research paper (scientific journal)

  10. Extracellular matrix protein tenascin-C is required in the bone marrow microenvironment primed for hematopoietic regeneration

    Ayako Nakamura-Ishizu, Yuji Okuno, Yoshiki Omatsu, Keisuke Okabe, Junko Morimoto, Toshimitsu Uede, Takashi Nagasawa, Toshio Suda, Yoshiaki Kubota

    BLOOD　Vol. 119　No. 23　p. 5429-5437　2012/06　Research paper (scientific journal)

  11. Isolation and function of mouse tissue resident vascular precursors marked by myelin protein zero

    Yoshiaki Kubota, Keiyo Takubo, Masanori Hirashima, Narihito Nagoshi, Kazuo Kishi, Yuji Okuno, Ayako Nakamura-Ishizu, Keigo Sano, Masato Murakami, Masatsugu Ema, Yoshiki Omatsu, Satoru Takahashi, Takashi Nagasawa, Masabumi Shibuya, Hideyuki Okano, Toshio Suda

    JOURNAL OF EXPERIMENTAL MEDICINE　Vol. 208　No. 5　p. 949-960　2011/05　Research paper (scientific journal)

  12. CXCL12-CXCR4 chemokine signaling is essential for NK-cell development in adult mice

    Mamiko Noda, Yoshiki Omatsu, Tatsuki Sugiyama, Shinya Oishi, Nobutaka Fujii, Takashi Nagasawa

    BLOOD　Vol. 117　No. 2　p. 451-458　2011/01　Research paper (scientific journal)

  13. Development of plasmacytoid dendritic cells in bone marrow stromal cell niches requires CXCL12-CXCR4 chemokine signaling

    Hiroshi Kohara, Yoshiki Omatsu, Tatsuki Sugiyama, Marniko Noda, Nobutaka Fujii, Takashi Nagasawa

    BLOOD　Vol. 110　No. 13　p. 4153-4160　2007/12　Research paper (scientific journal)

  14. Development of murine plasmacytoid dendritic cells defined by increased expression of an inhibitory NK receptor, Ly49Q

    Y Omatsu, T Iyoda, Y Kimura, A Maki, M Ishimori, N Toyama-Sorimachi, K Inaba

    JOURNAL OF IMMUNOLOGY　Vol. 174　No. 11　p. 6657-6662　2005/06　Research paper (scientific journal)

  15. Inhibitory NK receptor Ly49Q is expressed on subsets of dendritic cells in a cellular maturation- and cytokine stimulation-dependent manner

    N Toyama-Sorimachi, Y Omatsu, A Onoda, Y Tsujimura, T Iyoda, A Kikuchi-Maki, H Sorimachi, T Dohi, S Taki, K Inaba, H Karasuyama

    JOURNAL OF IMMUNOLOGY　Vol. 174　No. 8　p. 4621-4629　2005/04　Research paper (scientific journal)

  16. Functional comparison of the mouse DC-SIGN, SIGNR1, SIGNR3 and Langerin, C-type lectins

    K Takahara, Y Yashima, Y Omatsu, H Yoshida, Y Kimura, YS Kang, RM Steinman, CG Park, K Inaba

    INTERNATIONAL IMMUNOLOGY　Vol. 16　No. 6　p. 819-829　2004/06　Research paper (scientific journal)

  17. T(H)2 dominance and defective development of a CD8(+) dendritic cell subset in Id2-deficient mice

    T Kusunoki, M Sugai, T Katakai, Y Omatsu, T Iyoda, K Inaba, T Nakahata, A Shimizu, Y Yokota

    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY　Vol. 111　No. 1　p. 136-142　2003/01　Research paper (scientific journal)

  18. The CD8(+) dendritic cell subset selectively endocytoses dying cells in culture and in vivo

    T Iyoda, S Shimoyama, K Liu, Y Omatsu, Y Akiyama, Y Maeda, K Takahara, RM Steinman, K Inaba

    JOURNAL OF EXPERIMENTAL MEDICINE　Vol. 195　No. 10　p. 1289-1302　2002/05　Research paper (scientific journal)

  19. Identification and expression of mouse Langerin (CD207) in dendritic cells

    K Takahara, Y Omatsu, Y Yashima, Y Maeda, S Tanaka, T Iyoda, BE Clausen, K Matsubara, J Letterio, RM Steinman, Y Matsuda, K Inaba

    INTERNATIONAL IMMUNOLOGY　Vol. 14　No. 5　p. 433-444　2002/05　Research paper (scientific journal)

  20. Erratum: Identification and expression of mouse Langerin (CD207) in dendritic cells (International Immunology (2002) vol. 14 (433-444))

    Takahara, K., Omatsu, Y., Yashima, Y., Maeda, Y., Tanaka, S., Iyoda, T., Clausen, B.E., Matsubara, K., Letterio, J., Steinman, R.M., Matsuda, Y., Inaba, K.

    International Immunology　Vol. 14　No. 7　p. 831-831　2002　Research paper (scientific journal)

  21. Skin antigens in the steady state are trafficked to regional lymph nodes by transforming growth factor-beta 1-dependent cells

    H Hemmi, M Yoshino, H Yamazaki, M Naito, T Iyoda, Y Omatsu, S Shimoyama, JJ Letterio, T Nakabayashi, H Tagaya, T Yamane, M Ogawa, S Nishikawa, K Ryoke, K Inaba, S Hayashi, T Kunisada

    INTERNATIONAL IMMUNOLOGY　Vol. 13　No. 5　p. 695-704　2001/05　Research paper (scientific journal)

Misc. 16

  1. Identification of microenvironmental niches for hematopoietic stem cells and lymphoid progenitors—bone marrow fibroblastic reticular cells with salient features

    Yoshiki Omatsu, Takashi Nagasawa

    International Immunology　Vol. 33　No. 12　p. 821-826　2021/11/25

    Publisher: Oxford University Press ({OUP})

  2. Cellular Niches for Hematopoietic Stem Cells and Lympho-Hematopoiesis in Bone Marrow During Homeostasis and Blood Cancers

    Yoshiki Omatsu, Kei Higaki, Takashi Nagasawa

    Current Topics in Microbiology and Immunology　p. 33-54　2021

    Publisher: Springer International Publishing

  3. Niches for hematopoietic stem cells and immune cell progenitors

    Sugiyama, T., Omatsu, Y., Nagasawa, T.

    International Immunology　Vol. 31　No. 1　2018/08

  4. 造血幹細胞を維持する骨髄微小環境

    尾松芳樹

    Clinical calcium　Vol. 26　No. 5　p. 671-676　2016/05

  5. The niche for hematopoietic stem and progenitor cells in bone marrow

    Omatsu, Y.

    Clinical calcium　Vol. 26　No. 5　2016

  6. Foxc1 is a specific and critical transcriptional regulator of hematopoietic stem/progenitor cell niche formation and maintenance

    Vol. 64　No. 1　p. 85-89　2015/07

    Publisher: 科学評論社

  7. The critical and specific transcriptional regulator of the microenvironmental niche for hematopoietic stem and progenitor cells

    Omatsu, Y., Nagasawa, T.

    Current Opinion in Hematology　Vol. 22　No. 4　p. 330-336　2015/07

  8. 造血幹細胞ニッチの形成と維持に必須の転写因子Foxc1

    尾松 芳樹

    医学のあゆみ　Vol. 253　No. 8　p. 660-667　2015/05

  9. 造血幹細胞を維持する骨髄のニッチ

    長澤 丘司, 尾松 芳樹, 杉山 立樹

    実験医学　Vol. 32　No. 16　p. 2543-2550　2014/10

  10. ニッシェによる組織幹細胞の維持

    長澤丘司, 尾松芳樹, 杉山立樹

    実験医学Vol. 30 No 10（増刊）,21－28（2012）　2012

  11. 造血幹細胞のニッシェと造血調節

    長澤丘司, 尾松芳樹, 杉山立樹

    Anual Review 2012 血液 高久史麿、小澤敬也、坂田洋一、金倉譲、小島勢二編 中外医学社1－8（2012）　2012

  12. Control of hematopoietic stem cells by the bone marrow stromal niche: The role of reticular cells

    Nagasawa, T., Omatsu, Y., Sugiyama, T.

    Trends in Immunology　Vol. 32　No. 7　p. 315-320　2011/07

  13. 幹細胞の維持と血管性ニッチ (特集 血管新生を制御する--いかに血管を作り,そして壊せるか)

    長澤 丘司, 尾松 芳樹, 杉山 立樹

    細胞工学　Vol. 29　No. 11　p. 1082-1086　2010

  14. Role of CXCL12-CXCR4 chemokine signaling in the generation of plasma cytoid dendritic cells

    Kohara H, Omatsu Y, Sugiyama T, Noda M, Nagasawa T

    第37 回日本免疫学会（2007.11.21．東京）　2007

  15. Maturation and function of plasmacytoid dendritic cells

    Omatsu, Y., Iyoda, T., Maki, A., Ito, T., Fukuhara, S., Toyama-Sorimachi, N., Inaba, K.

    International Congress Series　Vol. 1285　p. 28-33　2005/11

    Publisher: International Congress Series

  16. Defective development of splenic and epidermal CD4(+) dendritic cells in mice deficient for IFN regulatory factor-2

    E Ichikawa, S Hida, Y Omatsu, S Shimoyama, K Takahara, S Miyagawa, K Inaba, S Taki

    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA　Vol. 101　No. 11　p. 3909-3914　2004/03

Institutional Repository 1

Content Published in the University of Osaka Institutional Repository (OUKA)

  1. Ebf3⁺ niche-derived CXCL12 is required for the localization and maintenance of hematopoietic stem cells

    Nakatani Taichi, Sugiyama Tatsuki, Omatsu Yoshiki, Watanabe Hitomi, Kondoh Gen, Nagasawa Takashi

    Nature Communications　Vol. 14　No. 1　2023/10/25