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研究

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尾松 芳樹

Omatsu Yoshiki

生命機能研究科 生命機能専攻,准教授

keyword ニッチ,造血幹細胞,血液学,免疫学

研究内容・専門分野

  • ライフサイエンス,免疫学

所属学会

  • 日本骨免疫学会
  • 日本免疫学会

論文

  • Ebf3+ niche-derived CXCL12 is required for the localization and maintenance of hematopoietic stem cells,Taichi Nakatani,Tatsuki Sugiyama,Yoshiki Omatsu,Hitomi Watanabe,Gen Kondoh,Takashi Nagasawa,Nature Communications,2023年10月25日,研究論文(学術雑誌)
  • Runx1 and Runx2 inhibit fibrotic conversion of cellular niches for hematopoietic stem cells,Yoshiki Omatsu,Shota Aiba,Tomonori Maeta,Kei Higaki,Kazunari Aoki,Hitomi Watanabe,Gen Kondoh,Riko Nishimura,Shu Takeda,Ung-il Chung,Takashi Nagasawa,Nature Communications,Springer Science and Business Media LLC,Vol. 13,No. 1,2022年12月,研究論文(学術雑誌)
  • Stem cell niche-specific Ebf3 maintains the bone marrow cavity,Masanari Seike,Yoshiki Omatsu,Hitomi Watanabe,Gen Kondoh,Takashi Nagasawa,Genes and Development,Cold Spring Harbor Laboratory Press,Vol. 32,No. 5-6,p. 359-372,2018年03月01日,研究論文(学術雑誌)
  • Foxc1 is a critical regulator of haematopoietic stem/progenitor cell niche formation,Yoshiki Omatsu,Masanari Seike,Tatsuki Sugiyama,Tsutomu Kume,Takashi Nagasawa,NATURE,NATURE PUBLISHING GROUP,Vol. 508,No. 7497,p. 536-+,2014年04月,研究論文(学術雑誌)
  • The Essential Functions of Adipo-osteogenic Progenitors as the Hematopoietic Stem and Progenitor Cell Niche,Yoshiki Omatsu,Tatsuki Sugiyama,Hiroshi Kohara,Gen Kondoh,Nobutaka Fujii,Kenji Kohno,Takashi Nagasawa,IMMUNITY,CELL PRESS,Vol. 33,No. 3,p. 387-399,2010年09月,研究論文(学術雑誌)
  • Cellular niches for hematopoietic stem cells in bone marrow under normal and malignant conditions,Yoshiki Omatsu,Inflammation and Regeneration,Springer Science and Business Media LLC,Vol. 43,No. 1,2023年02月21日,研究論文(学術雑誌)
  • A multistate stem cell dynamics maintains homeostasis in mouse spermatogenesis,Toshinori Nakagawa,David J. Jörg,Hitomi Watanabe,Seiya Mizuno,Seungmin Han,Tatsuro Ikeda,Yoshiki Omatsu,Keiko Nishimura,Miyako Fujita,Satoru Takahashi,Gen Kondoh,Benjamin D. Simons,Shosei Yoshida,Takashi Nagasawa,Cell Reports,Vol. 37,No. 3,p. 109875-109875,2021年10月,研究論文(学術雑誌)
  • Extracellular matrix protein tenascin-C is required in the bone marrow microenvironment primed for hematopoietic regeneration,Ayako Nakamura-Ishizu,Yuji Okuno,Yoshiki Omatsu,Keisuke Okabe,Junko Morimoto,Toshimitsu Uede,Takashi Nagasawa,Toshio Suda,Yoshiaki Kubota,BLOOD,AMER SOC HEMATOLOGY,Vol. 119,No. 23,p. 5429-5437,2012年06月,研究論文(学術雑誌)
  • Isolation and function of mouse tissue resident vascular precursors marked by myelin protein zero,Yoshiaki Kubota,Keiyo Takubo,Masanori Hirashima,Narihito Nagoshi,Kazuo Kishi,Yuji Okuno,Ayako Nakamura-Ishizu,Keigo Sano,Masato Murakami,Masatsugu Ema,Yoshiki Omatsu,Satoru Takahashi,Takashi Nagasawa,Masabumi Shibuya,Hideyuki Okano,Toshio Suda,JOURNAL OF EXPERIMENTAL MEDICINE,ROCKEFELLER UNIV PRESS,Vol. 208,No. 5,p. 949-960,2011年05月,研究論文(学術雑誌)
  • CXCL12-CXCR4 chemokine signaling is essential for NK-cell development in adult mice,Mamiko Noda,Yoshiki Omatsu,Tatsuki Sugiyama,Shinya Oishi,Nobutaka Fujii,Takashi Nagasawa,BLOOD,AMER SOC HEMATOLOGY,Vol. 117,No. 2,p. 451-458,2011年01月,研究論文(学術雑誌)
  • Development of plasmacytoid dendritic cells in bone marrow stromal cell niches requires CXCL12-CXCR4 chemokine signaling,Hiroshi Kohara,Yoshiki Omatsu,Tatsuki Sugiyama,Marniko Noda,Nobutaka Fujii,Takashi Nagasawa,BLOOD,AMER SOC HEMATOLOGY,Vol. 110,No. 13,p. 4153-4160,2007年12月,研究論文(学術雑誌)
  • Development of murine plasmacytoid dendritic cells defined by increased expression of an inhibitory NK receptor, Ly49Q,Y Omatsu,T Iyoda,Y Kimura,A Maki,M Ishimori,N Toyama-Sorimachi,K Inaba,JOURNAL OF IMMUNOLOGY,AMER ASSOC IMMUNOLOGISTS,Vol. 174,No. 11,p. 6657-6662,2005年06月,研究論文(学術雑誌)
  • Inhibitory NK receptor Ly49Q is expressed on subsets of dendritic cells in a cellular maturation- and cytokine stimulation-dependent manner,N Toyama-Sorimachi,Y Omatsu,A Onoda,Y Tsujimura,T Iyoda,A Kikuchi-Maki,H Sorimachi,T Dohi,S Taki,K Inaba,H Karasuyama,JOURNAL OF IMMUNOLOGY,AMER ASSOC IMMUNOLOGISTS,Vol. 174,No. 8,p. 4621-4629,2005年04月,研究論文(学術雑誌)
  • Functional comparison of the mouse DC-SIGN, SIGNR1, SIGNR3 and Langerin, C-type lectins,K Takahara,Y Yashima,Y Omatsu,H Yoshida,Y Kimura,YS Kang,RM Steinman,CG Park,K Inaba,INTERNATIONAL IMMUNOLOGY,OXFORD UNIV PRESS,Vol. 16,No. 6,p. 819-829,2004年06月,研究論文(学術雑誌)
  • T(H)2 dominance and defective development of a CD8(+) dendritic cell subset in Id2-deficient mice,T Kusunoki,M Sugai,T Katakai,Y Omatsu,T Iyoda,K Inaba,T Nakahata,A Shimizu,Y Yokota,JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY,MOSBY, INC,Vol. 111,No. 1,p. 136-142,2003年01月,研究論文(学術雑誌)
  • The CD8(+) dendritic cell subset selectively endocytoses dying cells in culture and in vivo,T Iyoda,S Shimoyama,K Liu,Y Omatsu,Y Akiyama,Y Maeda,K Takahara,RM Steinman,K Inaba,JOURNAL OF EXPERIMENTAL MEDICINE,ROCKEFELLER UNIV PRESS,Vol. 195,No. 10,p. 1289-1302,2002年05月,研究論文(学術雑誌)
  • Identification and expression of mouse Langerin (CD207) in dendritic cells,K Takahara,Y Omatsu,Y Yashima,Y Maeda,S Tanaka,T Iyoda,BE Clausen,K Matsubara,J Letterio,RM Steinman,Y Matsuda,K Inaba,INTERNATIONAL IMMUNOLOGY,OXFORD UNIV PRESS,Vol. 14,No. 5,p. 433-444,2002年05月,研究論文(学術雑誌)
  • Skin antigens in the steady state are trafficked to regional lymph nodes by transforming growth factor-beta 1-dependent cells,H Hemmi,M Yoshino,H Yamazaki,M Naito,T Iyoda,Y Omatsu,S Shimoyama,JJ Letterio,T Nakabayashi,H Tagaya,T Yamane,M Ogawa,S Nishikawa,K Ryoke,K Inaba,S Hayashi,T Kunisada,INTERNATIONAL IMMUNOLOGY,OXFORD UNIV PRESS,Vol. 13,No. 5,p. 695-704,2001年05月,研究論文(学術雑誌)

MISC

  • Identification of microenvironmental niches for hematopoietic stem cells and lymphoid progenitors—bone marrow fibroblastic reticular cells with salient features,Yoshiki Omatsu,Yoshiki Omatsu,Takashi Nagasawa,International Immunology,Oxford University Press ({OUP}),Vol. 33,No. 12,p. 821-826,2021年11月25日
  • Cellular Niches for Hematopoietic Stem Cells and Lympho-Hematopoiesis in Bone Marrow During Homeostasis and Blood Cancers,Yoshiki Omatsu,Yoshiki Omatsu,Kei Higaki,Takashi Nagasawa,Current Topics in Microbiology and Immunology,Springer International Publishing,p. 33-54,2021年
  • Niches for hematopoietic stem cells and immune cell progenitors,Sugiyama, T.,Omatsu, Y.,Nagasawa, T.,International Immunology,Vol. 31,No. 1,2018年08月
  • 造血幹細胞を維持する骨髄微小環境,尾松芳樹,Clinical calcium,Vol. 26,No. 5,p. 671-676,2016年05月
  • The niche for hematopoietic stem and progenitor cells in bone marrow,Omatsu, Y.,Clinical calcium,Vol. 26,No. 5,2016年
  • 造血幹細胞・前駆細胞と免疫細胞を維持するニッチの機能と制御機構,尾松 芳樹,臨床免疫・アレルギー科,科学評論社,Vol. 64,No. 1,p. 85-89,2015年07月
  • The critical and specific transcriptional regulator of the microenvironmental niche for hematopoietic stem and progenitor cells,Omatsu, Y.,Nagasawa, T.,Current Opinion in Hematology,LIPPINCOTT WILLIAMS & WILKINS,Vol. 22,No. 4,p. 330-336,2015年07月
  • 造血幹細胞ニッチの形成と維持に必須の転写因子Foxc1,尾松 芳樹,医学のあゆみ,Vol. 253,No. 8,p. 660-667,2015年05月
  • 造血幹細胞を維持する骨髄のニッチ,長澤 丘司,尾松 芳樹,杉山 立樹,実験医学,Vol. 32,No. 16,p. 2543-2550,2014年10月
  • ニッシェによる組織幹細胞の維持,長澤丘司,尾松芳樹,杉山立樹,実験医学Vol. 30 No 10(増刊),21-28(2012),2012年
  • 造血幹細胞のニッシェと造血調節,長澤丘司,尾松芳樹,杉山立樹,Anual Review 2012 血液 高久史麿、小澤敬也、坂田洋一、金倉譲、小島勢二編 中外医学社1-8(2012),2012年
  • Control of hematopoietic stem cells by the bone marrow stromal niche: The role of reticular cells,Nagasawa, T.,Omatsu, Y.,Sugiyama, T.,Trends in Immunology,ELSEVIER SCI LTD,Vol. 32,No. 7,p. 315-320,2011年07月
  • 幹細胞の維持と血管性ニッチ (特集 血管新生を制御する--いかに血管を作り,そして壊せるか),長澤 丘司,尾松 芳樹,杉山 立樹,細胞工学,Vol. 29,No. 11,p. 1082-1086,2010年
  • Role of CXCL12-CXCR4 chemokine signaling in the generation of plasma cytoid dendritic cells,Kohara H,Omatsu Y,Sugiyama T,Noda M,Nagasawa T,第37 回日本免疫学会(2007.11.21.東京),2007年
  • Maturation and function of plasmacytoid dendritic cells,Omatsu, Y.,Iyoda, T.,Maki, A.,Ito, T.,Fukuhara, S.,Toyama-Sorimachi, N.,Inaba, K.,International Congress Series,International Congress Series,Vol. 1285,p. 28-33,2005年11月
  • Defective development of splenic and epidermal CD4(+) dendritic cells in mice deficient for IFN regulatory factor-2,E Ichikawa,S Hida,Y Omatsu,S Shimoyama,K Takahara,S Miyagawa,K Inaba,S Taki,PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,NATL ACAD SCIENCES,Vol. 101,No. 11,p. 3909-3914,2004年03月

受賞

  • 日本免疫学会研究奨励賞,尾松 芳樹,日本免疫学会,2014年12月