Native sulfur/chlorine SAD phasing for serial femtosecond crystallography

Takanori Nakane, Changyong Song, Mamoru Suzuki, Eriko Nango, Jun Kobayashi, Tetsuya Masuda, Shigeyuki Inoue, Eiichi Mizohata, Toru Nakatsu, Tomoyuki Tanaka, Rie Tanaka, Tatsuro Shimamura, Kensuke Tono, Yasumasa Joti, Takashi Kameshima, Takaki Hatsui, Makina Yabashi, Osamu Nureki, So Iwata, Michihiro Sugahara

Acta Crystallographica Section D Biological Crystallography　Vol. 71　No. 12　p. 2519-2525　2015/12/01　Research paper (scientific journal)

Reversible and Massive Structural Transformation in Meltable Cyanido‐bridged Coordination Polymer Crystals

Yuudai Iwai, Saaya Kimura, Manabu Nakaya, Takanori Nakane, Akihiro Kawamoto, Genji Kurisu, Yuta Tsuji, Kenji Hirai, Koji Kimoto, Ovidiu Cretu, Fumitaka Takeiri, Kunihisa Sugimoto, Benjamin Le Ouay, Masaaki Ohba, Ryo Ohtani

Chemistry – A European Journal　2025/10/25　Research paper (scientific journal)

Polymorphism and Thermally Induced Structural Transformation in Semiconducting Cd(II) Coordination Polymers

Ryohei Akiyoshi, Honoka Motokawa, Asuka Nishibe, Atsuki Yanai, Takanori Nakane, Akihiro Kawamoto, Genji Kurisu, Akinori Saeki, Daichi Eguchi, Naoto Tamai, Yuki Mori, Shogo Kawaguchi, Kazuyoshi Ogasawara, Daisuke Tanaka

Inorganic Chemistry　2025/09/02　Research paper (scientific journal)

Beyond Serendipity: Uncovering Novel Ratiometric Urea•24DHBA Cocrystals through Mechanochemistry and MicroED

Ankur Bonia, Diptajyoti Gogoi, Nabadeep Kalita, Takanori Nakane, Akihiro Kawamoto, Khaled Althubeiti, Toshiyuki Sasaki, Genji Kurisu, Ranjit Thakuria

Chemical Communications　2025/09　Research paper (scientific journal)

Application of Multiple Small-wedge Synchrotron Crystallography for Post-reaction Structural Characterization of a Stimuli-responsive Small-molecule Crystal

Toshiyuki Sasaki, Takanori Nakane, Kazuyoshi Takimoto, Kouhei Ichiyanagi, Yuki Mori, Seiki Baba, Naoki Sakai, Genji Kurisu, Mikiji Miyata, Takahiro Uno, Takahito Itoh

Bulletin of the Chemical Society of Japan　2025/06　Research paper (scientific journal)

NMR-Based Rational Drug Design of G:G Mismatch DNA Binding Ligand Trapping Transient Complex via Disruption of a Key Allosteric Interaction

Shuhei Sakurabayashi, Kyoko Furuita, Takeshi Yamada, Noriaki Sugiura, Makoto Nomura, Takanori Nakane, Akihiro Kawamoto, Genji Kurisu, Yohei Miyanoiri, Toshimichi Fujiwara, Kazuhiko Nakatani, Chojiro Kojima

Journal of the American Chemical Society　2025/04/17　Research paper (scientific journal)

Tuning of a Hydrogen-Bonded Organic Framework by Liquid-Assisted Mechanosynthesis between Trans-Aconitic Acid and Isonicotinamide.

Diptajyoti Gogoi, Toshiyuki Sasaki, Nabadeep Kalita, Tapaswini Sethi, Kouhei Ichiyanagi, Takanori Nakane, Akihiro Kawamoto, Dinabandhu Das, Genji Kurisu, Ranjit Thakuria

Chemistry (Weinheim an der Bergstrasse, Germany)　2024/12/11　Research paper (scientific journal)

Analysis of Solid-State Emission of the p-Bis(2,2-dicyanovinyl)benzene Analogue through Combined X-ray, Synchrotron, and Microcrystal Electron Diffraction

Poonam Deka, Shilpi Jaiswal, Parishmita Sarma, Debajit Bora, Takanori Nakane, Akihiro Kawamoto, Yusuke Ohnishi, Genji Kurisu, Sanjeev Pran Mahanta, Khaled Althubeiti, Kouhei Ichiyanagi, Toshiyuki Sasaki, Ranjit Thakuria

Crystal Growth & Design　2024/08/23　Research paper (scientific journal)

Real-time observation of a metal complex-driven reaction intermediate using a porous protein crystal and serial femtosecond crystallography

Basudev Maity, Mitsuo Shoji, Fangjia Luo, Takanori Nakane, Satoshi Abe, Shigeki Owada, Jungmin Kang, Kensuke Tono, Rie Tanaka, Thuc Toan Pham, Mariko Kojima, Yuki Hishikawa, Junko Tanaka, Jiaxin Tian, Misaki Nagama, Taiga Suzuki, Hiroki Noya, Yuto Nakasuji, Asuka Asanuma, Xinchen Yao, So Iwata, Yasuteru Shigeta, Eriko Nango, Takafumi Ueno

Nature Communications　Vol. 15　No. 1　2024/06/29　Research paper (scientific journal)

Data-driven regularization lowers the size barrier of cryo-EM structure determination.

Dari Kimanius, Kiarash Jamali, Max E Wilkinson, Sofia Lövestam, Vaithish Velazhahan, Takanori Nakane, Sjors H W Scheres

Nature Methods　2024/06/11　Research paper (scientific journal)

Versatile Biaryls and Fused Aromatics through Oxidative Coupling of Hydroquinones with (Hetero)Arenes

Takaaki Aijima, Rina Ueda, Takanori Nakane, Fumiaki Makino, Yusuke Ohnishi, Jin Tokunaga, Keiichiro Nakajima, Shinichiro Kamino, Genji Kurisu, Keiichi Namba, Hiroki Nakata, Kaiki Mogi, Hironao Sajiki, Shuji Akai, Yoshinari Sawama

ChemistrySelect　Vol. 9　No. 15　2024/04/15　Research paper (scientific journal)

Mechanically-sensitive fluorochromism by molecular domino transformation in a Schiff base crystal

Toshiyuki Sasaki, Takanori Nakane, Akihiro Kawamoto, Yakai Zhao, Yushi Fujimoto, Tomohiro Nishizawa, Nabadeep Kalita, Seiji Tsuzuki, Fuyuki Ito, Upadrasta Ramamurty, Ranjit Thakuria, Genji Kurisu

Journal of Materials Chemistry C　2024/01　Research paper (scientific journal)

MicroED：どんな試料に適しているか

中根 崇智

PEPTIDE NEWSLETTER JAPAN　No. 130　2023/10　Research paper (conference, symposium, etc.)

Structure Elucidation of Olanzapine Molecular Salts by Combining Mechanochemistry and Micro-Electron Diffraction

Diptajyoti Gogoi, Toshiyuki Sasaki, Takanori Nakane, Akihiro Kawamoto, Hironobu Hojo, Genji Kurisu, Ranjit Thakuria

Crystal Growth & Design　Vol. 23　No. 8　p. 5821-5826　2023/06/27　Research paper (scientific journal)

Microcrystal electron diffraction (MicroED) structure determination of a mechanochemically synthesized co-crystal not affordable from solution crystallization

Toshiyuki Sasaki, Takanori Nakane, Akihiro Kawamoto, Tomohiro Nishizawa, Genji Kurisu

CrystEngComm　Vol. 25　p. 352-356　2022/12　Research paper (scientific journal)

Conformational alterations in unidirectional ion transport of a light-driven chloride pump revealed using X-ray free electron lasers.

Toshiaki Hosaka, Takashi Nomura, Minoru Kubo, Takanori Nakane, Luo Fangjia, Shun-Ichi Sekine, Takuhiro Ito, Kazutaka Murayama, Kentaro Ihara, Haruhiko Ehara, Kazuhiro Kashiwagi, Kazushige Katsura, Ryogo Akasaka, Tamao Hisano, Tomoyuki Tanaka, Rie Tanaka, Toshi Arima, Ayumi Yamashita, Michihiro Sugahara, Hisashi Naitow, Yoshinori Matsuura, Susumu Yoshizawa, Kensuke Tono, Shigeki Owada, Osamu Nureki, Tomomi Kimura-Someya, So Iwata, Eriko Nango, Mikako Shirouzu

Proceedings of the National Academy of Sciences of the United States of America　Vol. 119　No. 9　2022/03/01　Research paper (scientific journal)

High Resolution Structure Determination by Cryo-Electron Microscopy Single Particle Analysis

Takanori Nakane

日本結晶学会誌　Vol. 64　No. 2　2022　Research paper (scientific journal)

Crystal structure of CmABCB1 multi-drug exporter in lipidic mesophase revealed by LCP-SFX

Dongqing Pan, Ryo Oyama, Tomomi Sato, Takanori Nakane, Ryo Mizunuma, Keita Matsuoka, Yasumasa Joti, Kensuke Tono, Eriko Nango, So Iwata, Toru Nakatsu, Hiroaki Kato

IUCrJ　Vol. 9　No. 1　p. 134-145　2022/01/01　Research paper (scientific journal)

New tools for automated cryo-EM single-particle analysis in RELION-4.0.

Dari Kimanius, Liyi Dong, Grigory Sharov, Takanori Nakane, Sjors H W Scheres

The Biochemical journal　Vol. 478　No. 24　p. 4169-4185　2021/12/22　Research paper (scientific journal)

Pink beam crystallography demonstrated in SFX

Takanori Nakane

IUCrJ　Vol. 8　No. 6　p. 853-854　2021/11/01　Research paper (scientific journal)

Heavy Atom Detergent/Lipid Combined X-ray Crystallography for Elucidating the Structure-Function Relationships of Membrane Proteins

Shinya Hanashima, Takanori Nakane, Eiichi Mizohata

Membranes　2021/10　Research paper (scientific journal)

Capturing structural changes of the S1 to S2 transition of photosystem II using time-resolved serial femtosecond crystallography

Hongjie Li, Yoshiki Nakajima, Takashi Nomura, Michihiro Sugahara, Shinichiro Yonekura, Siu Kit Chan, Takanori Nakane, Takahiro Yamane, Yasufumi Umena, Mamoru Suzuki, Tetsuya Masuda, Taiki Motomura, Hisashi Naitow, Yoshinori Matsuura, Tetsunari Kimura, Kensuke Tono, Shigeki Owada, Yasumasa Joti, Rie Tanaka, Eriko Nango, Fusamichi Akita, Minoru Kubo, So Iwata, Jian-Ren Shen, Michihiro Suga

IUCrJ　Vol. 8　No. 3　p. 431-443　2021/05/01　Research paper (scientific journal)

Time-resolved serial femtosecond crystallography reveals early structural changes in channelrhodopsin

Kazumasa Oda, Takashi Nomura, Takanori Nakane, Keitaro Yamashita, Keiichi Inoue, Shota Ito, Johannes Vierock, Kunio Hirata, Andrés D Maturana, Kota Katayama, Tatsuya Ikuta, Itsuki Ishigami, Tamaki Izume, Rie Umeda, Ryuun Eguma, Satomi Oishi, Go Kasuya, Takafumi Kato, Tsukasa Kusakizako, Wataru Shihoya, Hiroto Shimada, Tomoyuki Takatsuji, Mizuki Takemoto, Reiya Taniguchi, Atsuhiro Tomita, Ryoki Nakamura, Masahiro Fukuda, Hirotake Miyauchi, Yongchan Lee, Eriko Nango, Rie Tanaka, Tomoyuki Tanaka, Michihiro Sugahara, Tetsunari Kimura, Tatsuro Shimamura, Takaaki Fujiwara, Yasuaki Yamanaka, Shigeki Owada, Yasumasa Joti, Kensuke Tono, Ryuichiro Ishitani, Shigehiko Hayashi, Hideki Kandori, Peter Hegemann, So Iwata, Minoru Kubo, Tomohiro Nishizawa, Osamu Nureki

eLife　Vol. 10　2021/03/23　Research paper (scientific journal)

Multi-body Refinement of Images in RELION

Takanori Nakane, Sjors H. W. Scheres

Methods in molecular biology　p. 145-160　2021　Part of collection (book)

Exploiting prior knowledge about biological macromolecules in cryo-EM structure determination

Dari Kimanius, Gustav Zickert, Takanori Nakane, Jonas Adler, Sebastian Lunz, Carola-Bibiane Schönlieb, Ozan Öktem, Sjors H. W. Scheres

IUCrJ　Vol. 8　No. 1　p. 60-75　2021/01/01　Research paper (scientific journal)

Structures and distributions of SARS-CoV-2 spike proteins on intact virions

Zunlong Ke, Joaquin Oton, Kun Qu, Mirko Cortese, Vojtech Zila, Lesley McKeane, Takanori Nakane, Jasenko Zivanov, Christopher J. Neufeldt, Berati Cerikan, John M. Lu, Julia Peukes, Xiaoli Xiong, Hans-Georg Kräusslich, Sjors H. W. Scheres, Ralf Bartenschlager, John A. G. Briggs

Nature　Vol. 588　No. 7838　p. 498-502　2020/12/17　Research paper (scientific journal)

Isoprenoid-chained lipid EROCOC17+4: a new matrix for membrane protein crystallization and a crystal delivery medium in serial femtosecond crystallography

Kentaro Ihara, Masakatsu Hato, Takanori Nakane, Keitaro Yamashita, Tomomi Kimura-Someya, Toshiaki Hosaka, Yoshiko Ishizuka-Katsura, Rie Tanaka, Tomoyuki Tanaka, Michihiro Sugahara, Kunio Hirata, Masaki Yamamoto, Osamu Nureki, Kensuke Tono, Eriko Nango, So Iwata, Mikako Shirouzu

Scientific Reports　Vol. 10　No. 1　2020/12　Research paper (scientific journal)

Structure of the dopamine D2 receptor in complex with the antipsychotic drug spiperone

Dohyun Im, Asuka Inoue, Takaaki Fujiwara, Takanori Nakane, Yasuaki Yamanaka, Tomoko Uemura, Chihiro Mori, Yuki Shiimura, Kanako Terakado Kimura, Hidetsugu Asada, Norimichi Nomura, Tomoyuki Tanaka, Ayumi Yamashita, Eriko Nango, Kensuke Tono, Francois Marie Ngako Kadji, Junken Aoki, So Iwata, Tatsuro Shimamura

Nature Communications　Vol. 11　No. 1　2020/12　Research paper (scientific journal)

Mitigating local over-fitting during single particle reconstruction with SIDESPLITTER

Kailash Ramlaul, Colin M. Palmer, Takanori Nakane, Christopher H.S. Aylett

Journal of Structural Biology　Vol. 211　No. 2　p. 107545-107545　2020/08　Research paper (scientific journal)

欧州における放射光施設と構造生物学データベースの動向

Takanori Nakane

実験医学　2020/03/18　Part of collection (book)

A tool for visualizing protein motions in time-resolved crystallography

Cecilia Wickstrand, Gergely Katona, Takanori Nakane, Przemyslaw Nogly, Joerg Standfuss, Eriko Nango, Richard Neutze

Structural Dynamics　2020/03　Research paper (scientific journal)

Comparing serial X-ray crystallography and microcrystal electron diffraction (MicroED) as methods for routine structure determination from small macromolecular crystals

Alexander M. Wolff, Iris D. Young, Raymond G. Sierra, Aaron S. Brewster, Michael W. Martynowycz, Eriko Nango, Michihiro Sugahara, Takanori Nakane, Kazutaka Ito, Andrew Aquila, Asmit Bhowmick, Justin T. Biel, Sergio Carbajo, Aina E. Cohen, Saul Cortez, Ana Gonzalez, Tomoya Hino, Dohyun Im, Jake D. Koralek, Minoru Kubo, Tomas S. Lazarou, Takashi Nomura, Shigeki Owada, Avi J. Samelson, Tomoyuki Tanaka, Rie Tanaka, Erin M. Thompson, Henry van den Bedem, Rahel A. Woldeyes, Fumiaki Yumoto, Wei Zhao, Kensuke Tono, Sebastien Boutet, So Iwata, Tamir Gonen, Nicholas K. Sauter, James S. Fraser, Michael C. Thompson

IUCrJ　Vol. 7　No. 2　p. 306-323　2020/03/01　Research paper (scientific journal)

Estimation of high-order aberrations and anisotropic magnification from cryo-EM data sets in RELION-3.1

Jasenko Zivanov, Takanori Nakane, Sjors H. W. Scheres

IUCrJ　Vol. 7　No. 2　p. 253-267　2020/03/01　Research paper (scientific journal)

High-viscosity sample-injection device for serial femtosecond crystallography at atmospheric pressure

Yoshiaki Shimazu, Kensuke Tono, Tomoyuki Tanaka, Yasuaki Yamanaka, Takanori Nakane, Chihiro Mori, Kanako Terakado Kimura, Takaaki Fujiwara, Michihiro Sugahara, Rie Tanaka, R. Bruce Doak, Tatsuro Shimamura, So Iwata, Eriko Nango, Makina Yabashi

Journal of Applied Crystallography　Vol. 52　No. 6　p. 1280-1288　2019/12/01　Research paper (scientific journal)

Improvement of Production and Isolation of Human Neuraminidase-1 in Cellulo Crystals

Kotaro Koiwai, Jun Tsukimoto, Tetsuya Higashi, Fumitaka Mafun{\'{e } }, Ken Miyajima, Takanori Nakane, Naohiro Matsugaki, Ryuichi Kato, Serena Sirigu, Arjen Jakobi, Matthias Wilmanns, Michihiro Sugahara, Tomoyuki Tanaka, Kensuke Tono, Yasumasa Joti, Makina Yabashi, Osamu Nureki, Eiichi Mizohata, Toru Nakatsu, Eriko Nango, So Iwata, Leonard M. G. Chavas, Toshiya Senda, Kohji Itoh, Fumiaki Yumoto

ACS Applied Bio Materials　Vol. 2　No. 11　p. 4941-4952　2019/11/18　Research paper (scientific journal)

Toward G protein-coupled receptor structure-based drug design using X-ray lasers

Andrii Ishchenko, Benjamin Stauch, Gye Won Han, Alexander Batyuk, Anna Shiriaeva, Chufeng Li, Nadia Zatsepin, Uwe Weierstall, Wei Liu, Eriko Nango, Takanori Nakane, Rie Tanaka, Kensuke Tono, Yasumasa Joti, So Iwata, Isabel Moraes, Cornelius Gati, Vadim Cherezov

IUCrJ　Vol. 6　No. 6　p. 1106-1119　2019/11/01　Research paper (scientific journal)

CryoTEM with a Cold Field Emission Gun That Moves Structural Biology into a New Stage

Takayuki Kato, Fumiaki Makino, Takanori Nakane, Naoya Terahara, Takeshi Kaneko, Yuko Shimizu, Sohei Motoki, Isamu Ishikawa, Koji Yonekura, Keiichi Namba

Microscopy and Microanalysis　Vol. 25　No. S2　p. 998-999　2019/08　Research paper (scientific journal)

Cryo-EM structure of the human L-type amino acid transporter 1 in complex with glycoprotein CD98hc

Yongchan Lee, Pattama Wiriyasermkul, Chunhuan Jin, Lili Quan, Ryuichi Ohgaki, Suguru Okuda, Tsukasa Kusakizako, Tomohiro Nishizawa, Kazumasa Oda, Ryuichiro Ishitani, Takeshi Yokoyama, Takanori Nakane, Mikako Shirouzu, Hitoshi Endou, Shushi Nagamori, Yoshikatsu Kanai, Osamu Nureki

Nature Structural & Molecular Biology　Vol. 26　No. 6　p. 510-517　2019/06　Research paper (scientific journal)

Crystal structure of plant vacuolar iron transporter VIT1

Takafumi Kato, Kaoru Kumazaki, Miki Wada, Reiya Taniguchi, Takanori Nakane, Keitaro Yamashita, Kunio Hirata, Ryuichiro Ishitani, Koichi Ito, Tomohiro Nishizawa, Osamu Nureki

Nature Plants　Vol. 5　No. 3　p. 308-315　2019/03/11　Research paper (scientific journal)

Ligand binding to human prostaglandin E receptor EP4 at the lipid-bilayer interface

Yosuke Toyoda, Kazushi Morimoto, Ryoji Suno, Shoichiro Horita, Keitaro Yamashita, Kunio Hirata, Yusuke Sekiguchi, Satoshi Yasuda, Mitsunori Shiroishi, Tomoko Shimizu, Yuji Urushibata, Yuta Kajiwara, Tomoaki Inazumi, Yunhon Hotta, Hidetsugu Asada, Takanori Nakane, Yuki Shiimura, Tomoya Nakagita, Kyoshiro Tsuge, Suguru Yoshida, Tomoko Kuribara, Takamitsu Hosoya, Yukihiko Sugimoto, Norimichi Nomura, Miwa Sato, Takatsugu Hirokawa, Masahiro Kinoshita, Takeshi Murata, Kiyoshi Takayama, Masaki Yamamoto, Shuh Narumiya, So Iwata, Takuya Kobayashi

Nature Chemical Biology　Vol. 15　No. 1　p. 18-26　2019/01　Research paper (scientific journal)

Recent Developments of Single Particle Analysis with Cryo-electron Microscopy

Takanori NAKANE

Nihon Kessho Gakkaishi　Vol. 60　No. 5-6　p. 230-232　2018/12/15　Research paper (scientific journal)

Crystal structure of the Agrobacterium tumefaciens type VI effector–immunity complex

Satoshi Fukuhara, Takanori Nakane, Keitaro Yamashita, Ryohei Ishii, Ryuichiro Ishitani, Osamu Nureki

Acta Crystallographica Section F Structural Biology Communications　Vol. 74　No. 12　p. 810-816　2018/12/01　Research paper (scientific journal)

Cryo-EM structures of the human volume-regulated anion channel LRRC8

Go Kasuya, Takanori Nakane, Takeshi Yokoyama, Yanyan Jia, Masato Inoue, Kengo Watanabe, Ryoki Nakamura, Tomohiro Nishizawa, Tsukasa Kusakizako, Akihisa Tsutsumi, Haruaki Yanagisawa, Naoshi Dohmae, Motoyuki Hattori, Hidenori Ichijo, Zhiqiang Yan, Masahide Kikkawa, Mikako Shirouzu, Ryuichiro Ishitani, Osamu Nureki

Nature Structural & Molecular Biology　Vol. 25　No. 9　p. 797-804　2018/09/20　Research paper (scientific journal)

Time-resolved serial femtosecond crystallography studies at an X-ray free electron laser reveals structural changes in bacteriorhodopsin

Richard Neutze, Eriko Nango, Tomoyuki Tanaka, Takanori Nakane, So Iwata, Antoine Royant, Jörg St, fuss, Przemyslaw Nogly, Cecilia Wickstr

Biochimica et Biophysica Acta (BBA) - Bioenergetics　Vol. 1859　2018/09　Research paper (scientific journal)

Structural basis for light control of cell development revealed by crystal structures of a myxobacterial phytochrome

Nicole C. Woitowich, Andrei S. Halavaty, Patricia Waltz, Christopher Kupitz, Joseph Valera, Gregory Tracy, Kevin D. Gallagher, Elin Claesson, Takanori Nakane, Suraj Pandey, Garrett Nelson, Rie Tanaka, Eriko Nango, Eiichi Mizohata, Shigeki Owada, Kensure Tono, Yasumasa Joti, Angela C. Nugent, Hardik Patel, Ayesha Mapara, James Hopkins, Phu Duong, Dorina Bizhga, Svetlana E. Kovaleva, Rachael St. Peter, Cynthia N. Hernandez, Wesley B. Ozarowski, Shatabdi Roy-Chowdhuri, Jay-How Yang, Petra Edlund, Heikki Takala, Janne Ihalainen, Jennifer Brayshaw, Tyler Norwood, Ishwor Poudyal, Petra Fromme, John C. H. Spence, Keith Moffat, Sebastian Westenhoff, Marius Schmidt, Emina A. Stojković

IUCrJ　Vol. 5　No. 5　p. 619-634　2018/09/01　Research paper (scientific journal)

Characterisation of molecular motions in cryo-EM single-particle data by multi-body refinement in RELION

Takanori Nakane, Dari Kimanius, Erik Lindahl, Sjors HW Scheres

eLife　Vol. 7　2018/06/01　Research paper (scientific journal)

Serial femtosecond crystallography at the SACLA: breakthrough to dynamic structural biology

Eiichi Mizohata, Takanori Nakane, Yohta Fukuda, Eriko Nango, So Iwata

Biophysical Reviews　Vol. 10　No. 2　p. 209-218　2018/04/01　Research paper (scientific journal)

Crystal Structures of Human Orexin 2 Receptor Bound to the Subtype-Selective Antagonist EMPA

Ryoji Suno, Kanako Terakado Kimura, Takanori Nakane, Keitaro Yamashita, Junmei Wang, Takaaki Fujiwara, Yasuaki Yamanaka, Dohyun Im, Shoichiro Horita, Hirokazu Tsujimoto, Maki S. Tawaramoto, Takatsugu Hirokawa, Eriko Nango, Kensuke Tono, Takashi Kameshima, Takaki Hatsui, Yasumasa Joti, Makina Yabashi, Keiko Shimamoto, Masaki Yamamoto, Daniel M. Rosenbaum, So Iwata, Tatsuro Shimamura, Takuya Kobayashi

Structure　Vol. 26　No. 1　p. 7-19.e5　2018/01　Research paper (scientific journal)

XFEL structures of the influenza M2 proton channel: Room temperature water networks and insights into proton conduction

Jessica L. Thomaston, Rahel A. Woldeyes, Takanori Nakane, Ayumi Yamashita, Tomoyuki Tanaka, Kotaro Koiwai, Aaron S. Brewster, Benjamin A. Barad, Yujie Chen, Thomas Lemmin, Monarin Uervirojnangkoorn, Toshi Arima, Jun Kobayashi, Tetsuya Masuda, Mamoru Suzuki, Michihiro Sugahara, Nicholas K. Sauter, Rie Tanaka, Osamu Nureki, Kensuke Tono, Yasumasa Joti, Eriko Nango, So Iwata, Fumiaki Yumoto, James S. Fraser, William F. DeGrado

Proceedings of the National Academy of Sciences　Vol. 114　No. 51　p. 13357-13362　2017/12/19　Research paper (scientific journal)

Structural basis for xenobiotic extrusion by eukaryotic MATE transporter

Hirotake Miyauchi, Satomi Moriyama, Tsukasa Kusakizako, Kaoru Kumazaki, Takanori Nakane, Keitaro Yamashita, Kunio Hirata, Naoshi Dohmae, Tomohiro Nishizawa, Koichi Ito, Takaaki Miyaji, Yoshinori Moriyama, Ryuichiro Ishitani, Osamu Nureki

Nature Communications　Vol. 8　No. 1　2017/12　Research paper (scientific journal)

Capturing an initial intermediate during the P450nor enzymatic reaction using time-resolved XFEL crystallography and caged-substrate

Takehiko Tosha, Takashi Nomura, Takuma Nishida, Naoya Saeki, Kouta Okubayashi, Raika Yamagiwa, Michihiro Sugahara, Takanori Nakane, Keitaro Yamashita, Kunio Hirata, Go Ueno, Tetsunari Kimura, Tamao Hisano, Kazumasa Muramoto, Hitomi Sawai, Hanae Takeda, Eiichi Mizohata, Ayumi Yamashita, Yusuke Kanematsu, Yu Takano, Eriko Nango, Rie Tanaka, Osamu Nureki, Osami Shoji, Yuka Ikemoto, Hironori Murakami, Shigeki Owada, Kensuke Tono, Makina Yabashi, Masaki Yamamoto, Hideo Ago, So Iwata, Hiroshi Sugimoto, Yoshitsugu Shiro, Minoru Kubo

Nature Communications　Vol. 8　No. 1　2017/12　Research paper (scientific journal)

Serial femtosecond crystallography structure of cytochrome c oxidase at room temperature

Rebecka Andersson, Cecilia Safari, Robert Dods, Eriko Nango, Rie Tanaka, Ayumi Yamashita, Takanori Nakane, Kensuke Tono, Yasumasa Joti, Petra Båth, Elin Dunevall, Robert Bosman, Osamu Nureki, So Iwata, Richard Neutze, Gisela Brändén

Scientific Reports　Vol. 7　No. 1　2017/12　Research paper (scientific journal)

Hydroxyethyl cellulose matrix applied to serial crystallography

Michihiro Sugahara, Takanori Nakane, Tetsuya Masuda, Mamoru Suzuki, Shigeyuki Inoue, Changyong Song, Rie Tanaka, Toru Nakatsu, Eiichi Mizohata, Fumiaki Yumoto, Kensuke Tono, Yasumasa Joti, Takashi Kameshima, Takaki Hatsui, Makina Yabashi, Osamu Nureki, Keiji Numata, Eriko Nango, So Iwata

Scientific Reports　Vol. 7　No. 1　2017/12　Research paper (scientific journal)

Structural insights into the competitive inhibition of the ATP-gated P2X receptor channel

Go Kasuya, Toshiaki Yamaura, Xiao-Bo Ma, Ryoki Nakamura, Mizuki Takemoto, Hiromitsu Nagumo, Eiichi Tanaka, Naoshi Dohmae, Takanori Nakane, Ye Yu, Ryuichiro Ishitani, Osamu Matsuzaki, Motoyuki Hattori, Osamu Nureki

Nature Communications　Vol. 8　No. 1　p. 876-876　2017/12　Research paper (scientific journal)

Coincidence timing of femtosecond optical pulses in an X-ray free electron laser

Alvaro Sanchez-Gonzalez, Allan S. Johnson, Ann Fitzpatrick, Christopher D. M. Hutchison, Clyde Fare, Violeta Cordon-Preciado, Gabriel Dorlhiac, Josie L. Ferreira, Rhodri M. Morgan, Jon P. Marangos, Shigeki Owada, Takanori Nakane, Rie Tanaka, Kensuke Tono, So Iwata, Jasper J. van Thor

Journal of Applied Physics　Vol. 122　No. 20　p. 203105-203105　2017/11/28　Research paper (scientific journal)

X-ray Free Electron Laser Determination of Crystal Structures of Dark and Light States of a Reversibly Photoswitching Fluorescent Protein at Room Temperature

Christopher Hutchison, Violeta Cordon-Preciado, Rhodri Morgan, Takanori Nakane, Josie Ferreira, Gabriel Dorlhiac, Alvaro Sanchez-Gonzalez, Allan Johnson, Ann Fitzpatrick, Clyde Fare, Jon Marangos, Chun Yoon, Mark Hunter, Daniel DePonte, Sébastien Boutet, Shigeki Owada, Rie Tanaka, Kensuke Tono, So Iwata, Jasper van Thor

International Journal of Molecular Sciences　Vol. 18　No. 9　p. 1918-1918　2017/09/07　Research paper (scientific journal)

Experimental phase determination with selenomethionine or mercury-derivatization in serial femtosecond crystallography

Keitaro Yamashita, Naoyuki Kuwabara, Takanori Nakane, Tomohiro Murai, Eiichi Mizohata, Michihiro Sugahara, Dongqing Pan, Tetsuya Masuda, Mamoru Suzuki, Tomomi Sato, Atsushi Kodan, Tomohiro Yamaguchi, Eriko Nango, Tomoyuki Tanaka, Kensuke Tono, Yasumasa Joti, Takashi Kameshima, Takaki Hatsui, Makina Yabashi, Hiroshi Manya, Tamao Endo, Ryuichi Kato, Toshiya Senda, Hiroaki Kato, So Iwata, Hideo Ago, Masaki Yamamoto, Fumiaki Yumoto, Toru Nakatsu

IUCrJ　Vol. 4　No. 5　p. 639-647　2017/09/01　Research paper (scientific journal)

Nanosecond pump–probe device for time-resolved serial femtosecond crystallography developed at SACLA

Minoru Kubo, Eriko Nango, Kensuke Tono, Tetsunari Kimura, Shigeki Owada, Changyong Song, Fumitaka Mafuné, Ken Miyajima, Yoshihiro Takeda, Jun-ya Kohno, Naoya Miyauchi, Takanori Nakane, Tomoyuki Tanaka, Takashi Nomura, Jan Davidsson, Rie Tanaka, Michio Murata, Takashi Kameshima, Takaki Hatsui, Yasumasa Joti, Richard Neutze, Makina Yabashi, So Iwata

Journal of Synchrotron Radiation　Vol. 24　No. 5　p. 1086-1091　2017/09/01　Research paper (scientific journal)

Atomic resolution structure of serine protease proteinase K at ambient temperature

Tetsuya Masuda, Mamoru Suzuki, Shigeyuki Inoue, Changyong Song, Takanori Nakane, Eriko Nango, Rie Tanaka, Kensuke Tono, Yasumasa Joti, Takashi Kameshima, Takaki Hatsui, Makina Yabashi, Bunzo Mikami, Osamu Nureki, Keiji Numata, So Iwata, Michihiro Sugahara

Scientific Reports　Vol. 7　No. 1　2017/05　Research paper (scientific journal)

Crystal Structure of the Minimal Cas9 from Campylobacter jejuni Reveals the Molecular Diversity in the CRISPR-Cas9 Systems

Mari Yamada, Yuto Watanabe, Jonathan S. Gootenberg, Hisato Hirano, F. Ann Ran, Takanori Nakane, Ryuichiro Ishitani, Feng Zhang, Hiroshi Nishimasu, Osamu Nureki

Molecular Cell　Vol. 65　No. 6　p. 1109-1121.e3　2017/03　Research paper (scientific journal)

Light-induced structural changes and the site of O=O bond formation in PSII caught by XFEL

Michihiro Suga, Fusamichi Akita, Michihiro Sugahara, Minoru Kubo, Yoshiki Nakajima, Takanori Nakane, Keitaro Yamashita, Yasufumi Umena, Makoto Nakabayashi, Takahiro Yamane, Takamitsu Nakano, Mamoru Suzuki, Tetsuya Masuda, Shigeyuki Inoue, Tetsunari Kimura, Takashi Nomura, Shinichiro Yonekura, Long-Jiang Yu, Tomohiro Sakamoto, Taiki Motomura, Jing-Hua Chen, Yuki Kato, Takumi Noguchi, Kensuke Tono, Yasumasa Joti, Takashi Kameshima, Takaki Hatsui, Eriko Nango, Rie Tanaka, Hisashi Naitow, Yoshinori Matsuura, Ayumi Yamashita, Masaki Yamamoto, Osamu Nureki, Makina Yabashi, Tetsuya Ishikawa, So Iwata, Jian-Ren Shen

Nature　Vol. 543　No. 7643　p. 131-135　2017/03　Research paper (scientific journal)

Serial Femtosecond Crystallography at SACLA: Current Situation and Future Prospects

Eriko NANGO, Takanori NAKANE, So IWATA

Nihon Kessho Gakkaishi　Vol. 59　No. 1　p. 12-17　2017　Research paper (scientific journal)

Damage-free protein structure determination by X-ray free electron laser

Takanori Nakane, So Iwata, Eiichi Mizohata

Seikagaku　Vol. 89　No. 4　p. 571-576　2017　Research paper (scientific journal)

Crystal structures of the TRIC trimeric intracellular cation channel orthologues

Go Kasuya, Masahiro Hiraizumi, Andrés D Maturana, Kaoru Kumazaki, Yuichiro Fujiwara, Keihong Liu, Yoshiko Nakada-Nakura, So Iwata, Keisuke Tsukada, Tomotaka Komori, Sotaro Uemura, Yuhei Goto, Takanori Nakane, Mizuki Takemoto, Hideaki E Kato, Keitaro Yamashita, Miki Wada, Koichi Ito, Ryuichiro Ishitani, Motoyuki Hattori, Osamu Nureki

Cell Research　Vol. 26　No. 12　p. 1288-1301　2016/12　Research paper (scientific journal)

Structural and Functional Analysis of DDX41: a bispecific immune receptor for DNA and cyclic dinucleotide

Hiroki Omura, Daisuke Oikawa, Takanori Nakane, Megumi Kato, Ryohei Ishii, Ryuichiro Ishitani, Fuminori Tokunaga, Osamu Nureki

Scientific Reports　Vol. 6　p. 34756-34756　2016/10/10　Research paper (scientific journal)

The room temperature crystal structure of a bacterial phytochrome determined by serial femtosecond crystallography

Petra Edlund, Heikki Takala, Elin Claesson, Leocadie Henry, Robert Dods, Heli Lehtivuori, Matthijs Panman, Kanupriya Pande, Thomas White, Takanori Nakane, Oskar Berntsson, Emil Gustavsson, Petra Bath, Vaibhav Modi, Shatabdi Roy-Chowdhury, James Zook, Peter Berntsen, Suraj Pandey, Ishwor Poudyal, Jason Tenboer, Christopher Kupitz, Anton Barty, Petra Fromme, Jake D. Koralek, Tomoyuki Tanaka, John Spence, Mengning Liang, Mark S. Hunter, Sebastien Boutet, Eriko Nango, Keith Moffat, Gerrit Groenhof, Janne Ihalainen, Emina A. Stojkovic, Marius Schmidt, Sebastian Westenhoff

SCIENTIFIC REPORTS　Vol. 6　2016/10　Research paper (scientific journal)

Crystal structure of the plant receptor-like kinase TDR in complex with the TDIF peptide

Junko Morita, Kazuki Kato, Takanori Nakane, Yuki Kondo, Hiroo Fukuda, Hiroshi Nishimasu, Ryuichiro Ishitani, Osamu Nureki

Nature Communications　Vol. 7　p. 12383-12383　2016/08/08　Research paper (scientific journal)

Crystal Structure of Cpf1 in Complex with Guide RNA and Target DNA

Takashi Yamano, Hiroshi Nishimasu, Bernd Zetsche, Hisato Hirano, Ian M. Slaymaker, Yinqing Li, Iana Fedorova, Takanori Nakane, Kira S. Makarova, Eugene V. Koonin, Ryuichiro Ishitani, Feng Zhang, Osamu Nureki

Cell　Vol. 165　No. 4　p. 949-962　2016/05　Research paper (scientific journal)

Oil-free hyaluronic acid matrix for serial femtosecond crystallography

Michihiro Sugahara, Changyong Song, Mamoru Suzuki, Tetsuya Masuda, Shigeyuki Inoue, Takanori Nakane, Fumiaki Yumoto, Eriko Nango, Rie Tanaka, Kensuke Tono, Yasumasa Joti, Takashi Kameshima, Takaki Hatsui, Makina Yabashi, Osamu Nureki, Keiji Numata, So Iwata

Scientific Reports　Vol. 6　p. 24484-24484　2016/04　Research paper (scientific journal)

Redox-coupled proton transfer mechanism in nitrite reductase revealed by femtosecond crystallography

Yohta Fukuda, Ka Man Tse, Takanori Nakane, Toru Nakatsu, Mamoru Suzuki, Michihiro Sugahara, Shigeyuki Inoue, Tetsuya Masuda, Fumiaki Yumoto, Naohiro Matsugaki, Eriko Nango, Kensuke Tono, Yasumasa Joti, Takashi Kameshima, Changyong Song, Takaki Hatsui, Makina Yabashi, Osamu Nureki, Michael E. P. Murphy, Tsuyoshi Inoue, So Iwata, Eiichi Mizohata

Proceedings of the National Academy of Sciences　Vol. 113　No. 11　p. 2928-2933　2016/03/15　Research paper (scientific journal)

Recent developments in CrystFEL

Thomas A. White, Valerio Mariani, Wolfgang Brehm, Oleks, r Yefanov, Anton Barty, Kenneth R. Beyerlein, Fedor Chervinskii, Lorenzo Galli, Cornelius Gati, Takanori Nakane, Alex, ra Tolstikova, Keitaro Yamashita, Chun Hong Yoon, Kay Diederichs, Henry N. Chapman

Journal of Applied Crystallography　Vol. 49　No. 2　p. 680-689　2016/03　Research paper (scientific journal)

Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance

Yasuaki Kabe, Takanori Nakane, Ikko Koike, Tatsuya Yamamoto, Yuki Sugiura, Erisa Harada, Kenji Sugase, Tatsuro Shimamura, Mitsuyo Ohmura, Kazumi Muraoka, Ayumi Yamamoto, Takeshi Uchida, So Iwata, Yuki Yamaguchi, Elena Krayukhina, Masanori Noda, Hiroshi Handa, Koichiro Ishimori, Susumu Uchiyama, Takuya Kobayashi, Makoto Suematsu

Nature Communications　Vol. 7　p. 11030-11030　2016/03　Research paper (scientific journal)

Structure and Engineering of Francisella novicida Cas9

Hisato Hirano, Jonathan S. Gootenberg, Takuro Horii, Omar O. Abudayyeh, Mika Kimura, Patrick D. Hsu, Takanori Nakane, Ryuichiro Ishitani, Izuho Hatada, Feng Zhang, Hiroshi Nishimasu, Osamu Nureki

Cell　Vol. 164　No. 5　p. 950-961　2016/02　Research paper (scientific journal)

Redox-coupled structural changes in nitrite reductase revealed by serial femtosecond and microfocus crystallography

Yohta Fukuda, Ka Man Tse, Mamoru Suzuki, Kay Diederichs, Kunio Hirata, Takanori Nakane, Michihiro Sugahara, Eriko Nango, Kensuke Tono, Yasumasa Joti, Takashi Kameshima, Changyong Song, Takaki Hatsui, Makina Yabashi, Osamu Nureki, Hiroyoshi Matsumura, Tsuyoshi Inoue, So Iwata, Eiichi Mizohata

Journal of Biochemistry　Vol. 159　No. 5　p. 527-538　2016/01　Research paper (scientific journal)

RCSB PDB Mobile: iOS and Android mobile apps to provide data access and visualization to the RCSB Protein Data Bank

G. B. Quinn, C. Bi, C. H. Christie, K. Pang, A. Prli, T. Nakane, C. Zardecki, M. Voigt, H. M. Berman, P. E. Bourne, P. W. Rose

Bioinformatics　Vol. 31　No. 1　p. 126-127　2015/01/01　Research paper (scientific journal)

iview: an interactive WebGL visualizer for protein-ligand complex

Hongjian Li, Kwong-Sak Leung, Takanori Nakane, Man-Hon Wong

BMC Bioinformatics　Vol. 15　No. 1　p. 56-56　2014　Research paper (scientific journal)

JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia

Robert M. Hanson, Jaime Prilusky, Zhou Renjian, Takanori Nakane, Joel L. Sussman

Israel Journal of Chemistry　Vol. 53　No. 3-4　p. 207-216　2013/04　Research paper (scientific journal)

Evaluation of the Pichia pastoris expression system for the production of GPCRs for structural analysis

Hidetsugu Asada, Tomoko Uemura, Takami Yurugi-Kobayashi, Mitsunori Shiroishi, Tatsuro Shimamura, Hirokazu Tsujimoto, Keisuke Ito, Taishi Sugawara, Takanori Nakane, Norimichi Nomura, Takeshi Murata, Tatsuya Haga, So Iwata, Takuya Kobayashi

Microbial Cell Factories　Vol. 10　No. 1　p. 24-24　2011　Research paper (scientific journal)