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Nakagawa Takuro
中川　拓郎
Nakagawa Takuro
中川　拓郎
Institutional repository
Center for Education in Liberal Arts and Sciences, Professor
nakagawa.takuro.sci osaka-u.ac.jp

keyword Transcription，Gross chromosomal rearrangement，DNA replication，fission yeast，centromere，chromosome，DNA recombination

Institutional repository

Research History 11

  1. 2025/04 - Present
    The University of Osaka　Center for Education in Liberal Arts and Sciences　Professor

  2. 2025/04 - Present
    The University of Osaka　Graduate School of Science

  3. 2025/04 - Present
    The University of Osaka　Institute for Radiation Sciences

  4. 2025/04 - Present
    The University of Osaka　The Museum of Osaka University

  5. 2025/04 - Present
    The University of Osaka

  6. 2022/04 - 2025/03
    The University of Osaka　Forefront Research Center

  7. 2018/04 - 2025/03
    The University of Osaka　Institute for Radiation Sciences

  8. 2011/02 - 2025/03
    Osaka University　Graduate School of Science　Associate Professor

  9. 2007/04 - 2011/01
    Osaka University　Graduate School of Science　Assistant Professor

  10. 2000/08 - 2007/03
    Osaka University　Graduate School of Science　Assistant Professor

  11. 1998/05 - 2000/07
    University of California San Diego (UCSD)　Ludwig Institute for Cancer Research　Postdoctoral Fellow

Education 3

  1. Osaka University　Graduate School of Science

    1995/04 - 1998/03

  2. Osaka University　Graduate School of Science

    1993/04 - 1995/03

  3. Osaka University　School of Science

    1989/04 - 1993/03

Committee Memberships 1

  1. 大阪大学 遺伝子組換え実験安全委員会　安全主任者

    2025/04 - Present

Professional Memberships 2

  1. THE GENETICS SOCIETY OF JAPAN

  2. 日本分子生物学会

Research Areas 2

  1. Life sciences / Molecular biology /

  2. Life sciences / Genetics /

Awards 8

  1. Excellent Poster Award

    Ran Xu, Crystal Tang, Takuro Nakagawa　The 12th 3R+3C International Symposium　2024/11

  2. The incentive award

    The genetics society of Japan　2021/08

  3. Reviewer of the Month

    Communications Biology (Springer Nature)　2020/04

  4. 総長奨励賞（研究部門）

    大阪大学　2015

  5. 教育・研究功績賞

    大阪大学　2009

  6. A long-term fellowship

    Human Frontier Science Program　1999

  7. 特別研究員（PD）

    日本学術振興会　1998

  8. 特別研究員（DC）

    日本学術振興会　1995

Papers 37

  1. Gross chromosomal rearrangement at centromeres

    Ran Xu, Ziyi Pan, Takuro Nakagawa

    Biomolecules　Vol. 14　No. 1　2024/01　Research paper (scientific journal)

  2. Fission yeast Srr1 and Skb1 promote isochromosome formation at the centromere

    Piyusha Mongia, Naoko Toyofuku, Ziyi Pan, Ran Xu, Yakumo Kinoshita, Keitaro Oki, Hiroki Takahashi, Yoshitoshi Ogura, Tetsuya Hayashi, Takuro Nakagawa

    Communications Biology　Vol. 6　No. 1　p. 551-551　2023/05/26　Research paper (scientific journal)

  3. Fission yeast Rad8/HLTF facilitates Rad52-dependent chromosomal rearrangements through PCNA lysine 107 ubiquitination.

    Jie Su, Ran Xu, Piyusha Mongia, Naoko Toyofuku, Takuro Nakagawa

    PLoS Genetics　Vol. 17　No. 7　2021/07　Research paper (scientific journal)

  4. DNA replication machinery prevents Rad52-dependent single-strand annealing that leads to gross chromosomal rearrangements at centromeres.

    Atsushi T Onaka, Jie Su, Yasuhiro Katahira, Crystal Tang, Faria Zafar, Keita Aoki, Wataru Kagawa, Hironori Niki, Hiroshi Iwasaki, Takuro Nakagawa

    Communications Biology　Vol. 3　No. 1　p. 202-202　2020/04/30　Research paper (scientific journal)

  5. Transcriptional silencing of centromere repeats by heterochromatin safeguards chromosome integrity.

    Nakagawa T, Okita AK

    Current Genetics　Vol. 65　No. 5　p. 1089-1098　2019/10　Research paper (scientific journal)

    Publisher: Springer Nature

  6. Heterochromatin suppresses gross chromosomal rearrangements at centromeres by repressing Tfs1/TFIIS-dependent transcription.

    Akiko K Okita, Faria Zafar, Jie Su, Dayalini Weerasekara, Takuya Kajitani, Tatsuro S Takahashi, Hiroshi Kimura, Yota Murakami, Hisao Masukata, Takuro Nakagawa

    Communications Biology　Vol. 2　p. 17-17　2019/01　Research paper (scientific journal)

  7. Shelterin promotes tethering of late replication origins to telomeres for replication‐timing control

    Shiho Ogawa, Sayuri Kido, Tetsuya Handa, Hidesato Ogawa, Haruhiko Asakawa, Tatsuro S Takahashi, Takuro Nakagawa, Yasushi Hiraoka, Hisao Masukata

    The EMBO Journal　Vol. 37　No. 15　2018/08　Research paper (scientific journal)

  8. Nucleosomes around a mismatched base pair are excluded via an Msh2-dependent reaction with the aid of SNF2 family ATPase Smarcad1

    Riki Terui, Koji Nagao, Yoshitaka Kawasoe, Kanae Taki, Torahiko L. Higashi, Seiji Tanaka, Takuro Nakagawa, Chikashi Obuse, Hisao Masukata, Tatsuro S. Takahashi

    Genes and Development　Vol. 32　No. 11-12　p. 806-821　2018/06/01　Research paper (scientific journal)

  9. Regulation of mitotic recombination between DNA repeats in centromeres

    Faria Zafar, Akiko K Okita, Atsushi T Onaka, Jie Su, Yasuhiro Katahira, Jun-ichi Nakayama, Tatsuro S Takahashi, Hisao Masukata, Takuro Nakagawa

    Nucleic Acids Research　Vol. 45　No. 19　p. 11222-11235　2017/11/02　Research paper (scientific journal)

  10. Rad51 and Rad54 promote noncrossover recombination between centromere repeats on the same chromatid to prevent isochromosome formation

    Atsushi T. Onaka, Naoko Toyofuku, Takahiro Inoue, Akiko K. Okita, Minami Sagawa, Jie Su, Takeshi Shitanda, Rei Matsuyama, Faria Zafar, Tatsuro S. Takahashi, Hisao Masukata, Takuro Nakagawa

    Nucleic Acids Research　Vol. 44　No. 22　p. 10744-10757　2016/12　Research paper (scientific journal)

  11. The heterochromatin protein Swi6/HP1 activates replication origins at the pericentromeric region and silent mating-type locus

    Makoto T. Hayashi, Tatsuro S. Takahashi, Takuro Nakagawa, Jun-ichi Nakayama, Hisao Masukata

    Nature Cell Biology　Vol. 11　No. 3　p. 357-U284　2009/03　Research paper (scientific journal)

  12. Rad51 suppresses gross chromosomal rearrangement at centromere in Schizosaccharomyces pombe

    Ken-ichi Nakamura, Aya Okamoto, Yuki Katou, Chie Yadani, Takeshi Shitanda, Chitrada Kaweeteerawat, Tatsuro S. Takahashi, Takehiko Itoh, Katsuhiko Shirahige, Hisao Masukata, Takuro Nakagawa

    The EMBO Journal　Vol. 27　No. 22　p. 3036-3046　2008/11　Research paper (scientific journal)

  13. Mcm4 C-terminal domain of MCM helicase prevents excessive formation of single-stranded DNA at stalled replication forks

    Naoki Nitani, Chie Yadani, Hayato Yabuuchi, Hisao Masukata, Takuro Nakagawa

    Proceedings of the National Academy of Sciences of the United States of America　Vol. 105　No. 35　p. 12973-12978　2008/09　Research paper (scientific journal)

  14. Genome-wide localization of pre-RC sites and identification of replication origins in fission yeast

    Makoto Hayashi, Yuki Katou, Takehiko Itoh, Mitsutoshi Tazumi, Yoshiki Yamada, Tatsuro Takahashi, Takuro Nakagawa, Katsuhiko Shirahige, Hisao Masukata

    The EMBO Journal　Vol. 26　No. 5　p. 1327-1339　2007/03　Research paper (scientific journal)

  15. Ordered assembly of Sld3, GINS and Cdc45 is distinctly regulated by DDK and CDK for activation of replication origins

    Hayato Yabuuchi, Yoshiki Yamada, Tomonori Uchida, Tul Sunathvanichkul, Takuro Nakagawa, Hisao Masukata

    The EMBO Journal　Vol. 25　No. 19　p. 4663-4674　2006/10　Research paper (scientific journal)

  16. Saccharomyces cerevisiae MER3 helicase stimulates 3 '-5 ' Heteroduplex extension by Rad51: Implications for crossover control in meiotic recombination

    OM Mazina, AV Mazin, T Nakagawa, RD Kolodner, SC Kowalczykowski

    Cell　Vol. 117　No. 1　p. 47-56　2004/04　Research paper (scientific journal)

  17. The MER3 DNA helicase catalyzes the unwinding of Holliday junctions

    T Nakagawa, RD Kolodner

    Journal of Biological Chemistry　Vol. 277　No. 31　p. 28019-28024　2002/08　Research paper (scientific journal)

  18. Saccharomyces cerevisiae Mer3 is a DNA helicase involved in meiotic crossing over

    T Nakagawa, RD Kolodner

    Molecular and Cellular Biology　Vol. 22　No. 10　p. 3281-3291　2002/05　Research paper (scientific journal)

  19. The MER3 helicase involved in meiotic crossing over is stimulated by single-stranded DNA-binding proteins and unwinds DNA in the 3 ' to 5 ' direction

    T Nakagawa, H Flores-Rozas, RD Kolodner

    Journal of Biological Chemistry　Vol. 276　No. 34　p. 31487-31493　2001/08　Research paper (scientific journal)

  20. The Saccharomyces cerevisiae MER3 gene, encoding a novel helicase-like protein, is required for crossover control in meiosis

    T Nakagawa, H Ogawa

    The EMBO Journal　Vol. 18　No. 20　p. 5714-5723　1999/10　Research paper (scientific journal)

  21. MutS alpha maintains the mismatch repair capability by inhibiting PCNA unloading

    Yoshitaka Kawasoe, Toshiki Tsurimoto, Takuro Nakagawa, Hisao Masukata, Tatsuro S. Takahashi

    ELIFE　Vol. 5　2016/07　Research paper (scientific journal)

  22. The DNA damage checkpoint pathway promotes extensive resection and nucleotide synthesis to facilitate homologous recombination repair and genome stability in fission yeast

    Elizabeth J. Blaikley, Helen Tinline-Purvis, Torben R. Kasparek, Samuel Marguerat, Sovan Sarkar, Lydia Hulme, Sharon Hussey, Boon-Yu Wee, Rachel S. Deegan, Carol A. Walker, Chen-Chun Pai, Juerg Baehler, Takuro Nakagawa, Timothy C. Humphrey

    Nucleic Acids Research　Vol. 42　No. 9　p. 5644-5656　2014　Research paper (scientific journal)

  23. Telomere-binding protein Taz1 controls global replication timing through its localization near late replication origins in fission yeast

    Atsutoshi Tazumi, Masayoshi Fukuura, Ryuichiro Nakato, Ami Kishimoto, Tomokazu Takenaka, Shiho Ogawa, Ji-hoon Song, Tatsuro S. Takahashi, Takuro Nakagawa, Katsuhiko Shirahige, Hisao Masukata

    Genes & Development　Vol. 26　No. 18　p. 2050-2062　2012/09　Research paper (scientific journal)

  24. DNA polymerization-independent functions of DNA polymerase epsilon in assembly and progression of the replisome in fission yeast

    Tetsuya Handa, Mai Kanke, Tatsuro S. Takahashi, Takuro Nakagawa, Hisao Masukata

    Molecular Biology of the Cell　Vol. 23　No. 16　p. 3240-3253　2012/08　Research paper (scientific journal)

  25. The Prereplication Complex Recruits XEco2 to Chromatin to Promote Cohesin Acetylation in Xenopus Egg Extracts

    Torahiko L. Higashi, Megumi Ikeda, Hiroshi Tanaka, Takuro Nakagawa, Masashige Bando, Katsuhiko Shirahige, Yumiko Kubota, Haruhiko Takisawa, Hisao Masukata, Tatsuro S. Takahashi

    Current Biology　Vol. 22　No. 11　p. 977-988　2012/06　Research paper (scientific journal)

  26. Mcm10 plays an essential role in origin DNA unwinding after loading of the CMG components

    Mai Kanke, Yukako Kodama, Tatsuro S. Takahashi, Takuro Nakagawa, Hisao Masukata

    The EMBO Journal　Vol. 31　No. 9　p. 2182-2194　2012/05　Research paper (scientific journal)

  27. Abundance of Prereplicative Complexes (Pre-RCs) Facilitates Recombinational Repair under Replication Stress in Fission Yeast

    Kentaro Maki, Takahiro Inoue, Atsushi Onaka, Hiroko Hashizume, Naoko Somete, Yuko Kobayashi, Shigefumi Murakami, Chikako Shigaki, Tatsuro S. Takahashi, Hisao Masukata, Takuro Nakagawa

    Journal of Biological Chemistry　Vol. 286　No. 48　p. 41701-41710　2011/12　Research paper (scientific journal)

  28. CDK promotes interactions of Sld3 and Drc1 with Cut5 for initiation of DNA replication in fission yeast

    Masayoshi Fukuura, Koji Nagao, Chikashi Obuse, Tatsuro S. Takahashi, Takuro Nakagawa, Hisao Masukata

    Molecular Biology of the Cell　Vol. 22　No. 14　p. 2620-2633　2011/07　Research paper (scientific journal)

  29. Auxin-inducible protein depletion system in fission yeast

    Mai Kanke, Kohei Nishimura, Kohei Nishimura, Masato Kanemaki, Masato Kanemaki, Tatsuo Kakimoto, Tatsuro S. Takahashi, Takuro Nakagawa, Hisao Masukata

    BMC Cell Biology　Vol. 12, 8, doi:10.1186/1471-2121-12-8　2011/02/11　Research paper (scientific journal)

  30. Erratum: Genome-wide localization of pre-RC sites and identification of replication origins in fission yeast (The EMBO Journal (2007) 26 (1327-1339) DOI: 10.1038/sj.emboj.7601585)

    Hayashi, M., Katou, Y., Itoh, T., Tazumi, A., Yamada, Y., Takahashi, T., Nakagawa, T., Shirahige, K., Masukata, H.

    EMBO Journal　Vol. 26　No. 11　p. 2821-2821　2007　Research paper (scientific journal)

  31. Regulation of DNA replication machinery by Mrc1 in fission yeast

    Naoki Nitani, Ken-ichi Nakamura, Chie Nakagawa, Hisao Masukata, Takuro Nakagawa

    Genetics　Vol. 174　No. 1　p. 155-165　2006/09　Research paper (scientific journal)

  32. A novel intermediate in initiation complex assembly for fission yeast DNA replication

    Y Yamada, T Nakagawa, H Masukata

    Molecular Biology of the Cell　Vol. 15　No. 8　p. 3740-3750　2004/08　Research paper (scientific journal)

  33. A novel allele of fission yeast rad11 that causes defects in DNA repair and telomere length regulation

    Y Ono, K Tomita, A Matsuura, T Nakagawa, H Masukata, M Uritani, T Ushimaru, M Ueno

    Nucleic Acids Research　Vol. 31　No. 24　p. 7141-7149　2003/12　Research paper (scientific journal)

  34. A novel allele of fission yeast radii that causes defects in DNA repair and telomere length regulation

    Y. Ono, K. Tomita, A. Matsuura, T. Nakagawa, H. Masukata, M. Uritani, T. Ushimaru, M. Ueno

    KURRI Progress Report　2003/04　Research paper (scientific journal)

  35. Multiple functions of MutS- and MutL-related heterocomplexes

    T Nakagawa, A Datta, RD Kolodner

    Proceedings of the National Academy of Sciences of the United States of America　Vol. 96　No. 25　p. 14186-14188　1999/12

  36. Involvement of the MRE2 gene of yeast in formation of meiosis-specific double-strand breaks and crossover recombination through RNA splicing

    T Nakagawa, H Ogawa

    Genes to Cells　Vol. 2　No. 1　p. 65-79　1997/01　Research paper (scientific journal)

  37. Functions of the yeast meiotic recombination genes, MRE11 and MRE2

    Ogawa H, Johzuka K, Nakagawa T, Leem SH, Hagihara AH

    Advances in Biophysics　Vol. 31　No. C　p. 67-76　1995　Research paper (scientific journal)

    Publisher: Elsevier BV

Misc. 8

  1. 染色体異常の発生メカニズム

    中川拓郎

    未来社会共創を目指す「研究シーズ集2025」　2025/03　Article, review, commentary, editorial, etc. (other)

    Publisher: 大阪大学 共創機構 産学官連携オフィス

  2. Gross chromosomal rearrangements at the centromere

    Takuro Nakagawa

    Medical Science Digest　Vol. 49　No. 9　p. 64-66　2023/08　Rapid communication, short report, research note, etc. (scientific journal)

  3. ゲノム編集なき遺伝子治療へ

    中川拓郎

    ダイヤモンド社「週刊ダイヤモンド」　Vol. 107　No. 41　p. 51-51　2019/10　Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)

  4. Rad51 and Rad54 promote noncrossover recombination between centromere repeats to prevent isochromosome formation

    Takuro Nakagawa, Atsushi Onaka, Tatsuro S. Takahashi, Hisao Masukata

    GENES & GENETIC SYSTEMS　Vol. 91　No. 6　p. 372-372　2016/12　Research paper, summary (international conference)

  5. Fission yeast CENP-T nucleosomes promote the isochromosome formation in centromere

    Jie Su, Akiko Okita, Tatsuro Takahashi, Hisao Masukata, Takuro Nakagawa

    GENES & GENETIC SYSTEMS　Vol. 90　No. 6　p. 377-377　2015/12　Research paper, summary (international conference)

  6. Molecular mechanism of gross chromosomal rearrangements in centromere

    Takuro Nakagawa

    GENES & GENETIC SYSTEMS　Vol. 89　No. 6　p. 283-283　2014/12　Research paper, summary (international conference)

  7. The centromere integrity is maintained through the function of kinetochore proteins CENP-SX

    Takuro Nakagawa

    GENES & GENETIC SYSTEMS　Vol. 88　No. 6　p. 340-340　2013/12　Research paper, summary (international conference)

  8. Inhibition of nucleosome assembly by the mismatch repair system

    Tatsuro Takahashi, Kanae Taki, Torahiko Higashi, Takuro Nakagawa, Hisao Masukata

    FASEB JOURNAL　Vol. 24　2010/04　Research paper, summary (international conference)

Publications 2

  1. Institute for Radiation Sciences (IRS) Annual Report 2018-2019

    Akiko K. Okita, Takuro Nakagawa

    2020/10

  2. Fundamental Aspects of DNA Replication

    Zafar F, Nakagawa T

    InTech, Rijeka, Croatia　2011/09　Scholarly book

    ISBN: 9789533072593

Presentations 42

  1. 染色体異常の発生メカニズムの解明

    中川拓郎

    FRC談話会（第７回）　2025/03/21

  2. セントロメア領域での染色体異常の発生メカニズム

    中川拓郎, Xu Ran, Tang Crystal

    染色体ワークショップ（第42回）・核ダイナミクス研究会（第23回）　2025/01/30

  3. セントロメア反復配列の転写による染色体異常の発生機構

    中川拓郎

    「先進ゲノム支援」拡大班会議　2024/12/27

  4. Recurrent transcriptional pausing and restart at centromeres causes gross chromosomal rearrangements through R-loop formation

    Ran Xu, Crystal Tang, Takuro Nakagawa

    The 12th 3R+3C International Symposium　2024/11/21

  5. Fission yeast Cnp1/CENP-A causes gross chromosomal rearrangements at centromeres

    Takuro Nakagawa, Shinnosuke Tomita, Ziyi Pan

    The 12th 3R+3C International Symposium　2024/11/21

  6. 染色体異常の発生メカニズム

    中川拓郎

    理学研究フォーラム（第14回）　2024/11/05

  7. 分裂酵母Cnp1/CENP-Aによるセントロメア領域での染色体異常の誘発

    Pan Ziyi, 富田慎之介, 中川拓郎

    日本遺伝学会（第96回）　2024/09/04

  8. セントロメア領域における染色体異常の発生メカニズム

    中川拓郎

    日本遺伝性腫瘍学会学術集会（第30回）　2024/06/01

  9. セントロメア領域の転写による染色体異常の発生

    中川 拓郎, Xu Ran, Tang Crystal

    染色体ワークショップ（第41回）・核ダイナミクス研究会（第22回）　2024/01/29

  10. Transcription of centromeric DNA repeats causes gross chromosomal rearrangement

    Takuro Nakagawa

    2023/12/26

  11. Transcriptional restart causes chromosomal rearrangements through DR-loop formation at centromeres

    Ran Xu, Crystal Tang, Takuro Nakagawa

    2023/12/06

  12. Fission yeast Srr1 and CENP-A cause gross chromosomal rearrangement at centromeres

    Ziyi Pan, Takuro Nakagawa

    The 46th Annual Meeting of the Molecular Biology Society of Japan　2023/12/06

  13. Transcriptional Restart Causes Chromosomal Rearrangements at the Centromere

    Takuro Nakagawa

    Celebrating 32 Years of Ludwig San Diego: Insights into Genome Integrity and Regulation in Cancer　2023/10/17

  14. Transcriptional restart causes chromosomal rearrangements at centromeres

    Ran Xu, Crystal Tang, Takuro Nakagawa

    CSH Conference Asia: Yeast and Life Sciences　2023/10/11

  15. Centromere transcription causes gross chromosomal rearrangements

    Takuro Nakagawa, Ran Xu, Crystal Tang

    2023/09/07

  16. 染色体セントロメア領域の転写による染色体異常の発生機構

    中川 拓郎, Xu Ran, Tang Crystal

    第27回 DNA複製、組換え、修復ワークショップ　2023/06/06

  17. Srr1/Ber1 promotes isochromosomes formation at centromeres

    Ziyi Pan, Piyusha Mongia, Ran Xu, Naoko Toyofuku, Takuro Nakagawa

    The 11th International Fission Yeast Meeting　2023/05/29

  18. Transcriptional restart causes chromosomal rearrangements at the centromere

    Ran Xu, Crystal Tang, Takuro Nakagawa

    The 11th International Fission Yeast Meeting　2023/06/01

  19. Transcriptional restart forms DNA-RNA hybrids that cause centromere instability

    Ran Xu, Crystal Tang, Yakumo Kinoshita, Takuro Nakagawa

    The 19th international Ataxia-Telangiectasia Workshop 2023　2023/03/05

  20. Transcription of centromeric DNA repeats causes gross chromosomal rearrangement

    Takuro Nakagawa

    2023/01/20

  21. 転写因子Tfs1によるDNA-RNA形成を介した染色体異常の発生

    中川拓郎, Xu Ran, Tang Crystal

    染色体ワークショップ（第40回）・核ダイナミクス研究会（第21回）　2022/12/20

  22. 転写因子Tfs1/TFIISはDNA-RNAハイブリッド形成を促進することでセントロメアでの染色体異常を誘発する

    Xu Ran, Tang Crystal, 中川拓郎

    日本分子生物学会（第45回）　2022/11/30

  23. 分裂酵母Srr1とSkb1はセントロメア領域のDNA反復配列を介した染色体異常を促進する

    Mongia Piyusha, Ziyi Pan, 沖慶太郎, 豊福直子, 中川拓郎

    日本分子生物学会（第45回）　2022/11/30

  24. ヘテロクロマチン構造による転写制御を介した染色体異常の抑制

    Xu Ran, Tang Crystal, 中川拓郎

    日本生化学大会（第95回）　2022/11/11

  25. Transcription causes gross chromosomal rearrangements at the centromere through R-loop formation

    Ran Xu, Crystal Tn, Takuro Nakagawa

    2022/09/15

  26. Heterochromatin suppresses gross chromosomal rearrangements at centromeres.

    Takuro Nakagawa

    National Tsing Hua University-Osaka University (NTHU-OU) virtual symposium on biological and medical science　2022/01/19

  27. Ber1 and Skb1 cause gross chromosomal rearrangements at centromeres in rad51∆ cells.

    Piyusha Mongia, Naoko Toyofuku, Takuro Nakagawa

    2021/12/02

  28. Heterochromatin prevents DNA-RNA hybrid formation that causes gross chromosomal rearrangements at centromeres.

    Ran Xu, Crystal Tang, Takuro Nakagawa

    2021/12/02

  29. 染色体異常の分子メカニズム

    中川拓郎

    日本遺伝学会（第93回大会）　2021/09/10

  30. Rad8-dependent PCNA ubiquitination at lysine 107 promotes gross chromosomal rearrangements.

    Jie Su, Takuro Nakagawa

    Pombe Talks　2021/07/21

  31. Mechanism of gross chromosomal rearrangements.

    Takuro Nakagawa

    International Summer Program (ISP), School of Science, Graduate School of Science, Osaka University　2021/07/15

  32. 染色体異常の分子メカニズム

    中川拓郎

    日本分子生物学会（第43回）　2020/12/02

  33. R ループは分裂酵母のセントロメア領域での染色体異常を引き起こす

    Crystal Tang, 中川拓郎

    染色体ワークショップ（第37回）・核ダイナミクス研究会（第18回）　2019/12/23

  34. 分裂酵母 Rad8 は PCNA K107 のユビキチン化を介してセントロメア領域での染色体異常を引き起こす

    中川拓郎, 豊福直子, 蘇傑

    染色体ワークショップ（第37回）・核ダイナミクス研究会（第18回）　2019/12/23

  35. 分裂酵母Rad8/Rad5/HLTFによる染色体異常の分子機構

    中川拓郎, 豊福直子, 沖慶太郎, 蘇

    DNA 複製・組換え・修復ワークショップ（第25回）　2019/11/11

  36. 分裂酵母を用いた染色体異常の分子メカニズムの研究

    中川拓郎, 沖田暁子, 蘇傑, F. Zafar, C. Tang

    理学研究フォーラム（第11回 ）研究交流セミナー（第10回 ）　2019/03/08

  37. 分裂酵母を用いた染色体異常の分子機構の解明

    中川拓郎

    国立遺伝学研究所・研究集会「ゲノムの維持継承を支える分子基盤の包括的理解とその発展」　2019/02/14

  38. Heterochromatin suppresses gross chromosomal rearrangements at centromeres

    Nakagawa, T, Zafar, F, Su, J, Weerasekara, D, Kajitani, T, Takahashi, TS, Kimura, H, Murakami, Y, Masukata, H, Okita, AK

    第２０回武田科学振興財団生命科学シンポジウム「RNAネオバイオロジー」　2019/02/01

  39. ヘテロクロマチンによる染色体異常の抑制

    中川拓郎, 沖田暁子

    染色体ワークショップ（第36回）・核ダイナミクス研究会（第17回）　2019/01/23

  40. ヘテロクロマチンによる転写制御を介した染色体異常の抑制機構

    中川拓郎, Weerasekara, D, 蘇傑, Zafar, F, 高橋達郎, 升方久夫, 梶谷卓也, 木村宏, 村上洋太, 沖田暁子

    日本分子生物学会（第41回）　2018/11/28

  41. Heterochromatin suppresses gross chromosomal rearrangements at centromeres

    Okita AK, Zafar F, Su J, Weerasekara D, Kajitani T, Takahashi TS, Kimura H, Murakami Y, Masukata H, Nakagawa T

    The 11th 3R Symposium　2018/11/13

  42. ヘテロクロマチンによる染色体異常の抑制

    沖田暁子, D. Weerasekara, J. Su, F. Zafar, 中川拓郎

    日本遺伝学会年会（第90回）　2018/09/19

Media Coverage 2

  1. Ubiquitination of PCNA induces chromosomal abnormalities: expectations for future development of therapeutic agents.

    JST (Japan Science and Technology Agency)

    2021/10

  2. Study on chromosomal rearrangements in yeast reveals potential avenue for cancer therapy

    The American Association for the Advancement of Science (AAAS)

    2021/07

Academic Activities 1

  1. Genes & Genetic Systems (GGS) Prize Editor

    The Genetics Society of Japan

    2023/06 -

Institutional Repository 2

Content Published in the University of Osaka Institutional Repository (OUKA)

  1. Fission yeast Srr1 and Skb1 promote isochromosome formation at the centromere

    Mongia Piyusha, Toyofuku Naoko, Pan Ziyi, Xu Ran, Kinoshita Yakumo, Oki Keitaro, Takahashi Hiroki, Ogura Yoshitoshi, Hayashi Tetsuya, Nakagawa Takuro

    Communications Biology　Vol. 6　2023/05/26

  2. The Regulation of RNA Splicing and the Role of Mer3 Helicase in Meiotic Recombination

    中川 拓郎