Insight into the function of voltage-sensing phosphatase in hindgut-derived pseudoplacenta of a viviparous teleost Xenotoca eiseni

Adisorn Ratanayotha, Atsuo Iida, Jumpei Nomura, Eiichi Hondo, Yasushi Okamura, Takafumi Kawai

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology　Vol. 326　No. 6　p. R461-R471　2024/06/01　Research paper (scientific journal)

電位依存性ホスホイノシチドホスファターゼVSP：発見から約20年を経て

岡村 康司

生化学(Journal of Japanese Biochemical Society ）　Vol. 96　No. 2　p. 255-268　2024/04　Research paper (other academic)

Structural change of the cytoplasmic N‐terminus and <scp>S1</scp> segment of voltage‐sensing phosphatase reported by Anap

Hidekazu Tsutsui, Yuka Jinno, Natsuki Mizutani, Yasushi Okamura

Acta Physiologica　2024/03/19　Research paper (scientific journal)

(R)-ketamine restores anterior insular cortex activity and cognitive deficits in social isolation-reared mice

Rei Yokoyama, Yukio Ago, Hisato Igarashi, Momoko Higuchi, Masato Tanuma, Yuto Shimazaki, Takafumi Kawai, Kaoru Seiriki, Misuzu Hayashida, Shun Yamaguchi, Hirokazu Tanaka, Takanobu Nakazawa, Yasushi Okamura, Kenji Hashimoto, Atsushi Kasai, Hitoshi Hashimoto

Molecular Psychiatry　Vol. 29　No. 5　p. 1406-1416　2024/02/23　Research paper (scientific journal)

What voltage-sensing phosphatases can reveal about the mechanisms of ion channel regulation by phosphoinositides

Yasushi Okamura, Daisuke Yoshioka

Biochemical Society Transactions　Vol. 51　No. 2　p. 827-839　2023/04/13　Research paper (scientific journal)

Role of K364 next to the active site cysteine in voltage-dependent phosphatase activity of Ci-VSP.

Ian Costa Paixao, Natsuki Mizutani, Makoto Matsuda, Rizki Tsari Andriani, Takafumi Kawai, Atsushi Nakagawa, Yoshifumi Okochi, Yasushi Okamura

Biophysical journal　Vol. 122　No. 11　p. 2267-2284　2023/01/19　Research paper (scientific journal)

Critical contributions of pre-S1 shoulder and distal TRP box in DAG-activated TRPC6 channel by PIP2 regulation

Masayuki X. Mori, Ryo Okada, Reiko Sakaguchi, Hideharu Hase, Yuko Imai, Onur K. Polat, Satoru G. Itoh, Hisashi Okumura, Yasuo Mori, Yasushi Okamura, Ryuji Inoue

Scientific Reports　Vol. 12　No. 1　2022/12　Research paper (scientific journal)

Voltage-sensing phosphatase (Vsp) regulates endocytosis-dependent nutrient absorption in chordate enterocytes

Adisorn Ratanayotha, Makoto Matsuda, Yukiko Kimura, Fumiko Takenaga, Tomoaki Mizuno, Md. Israil Hossain, Shin-ichi Higashijima, Takafumi Kawai, Michio Ogasawara, Yasushi Okamura

Communications Biology　Vol. 5　No. 948　p. 1-15　2022/09/10　Research paper (scientific journal)

神経興奮のイオン機構の発見

岡村康司

Clinical Neuroscience別冊 ノーベル賞の神経科学　Vol. 407　No. 8　p. 964-968　2022/08

Spotlight on the Binding Affinity of Ion Channels for Phosphoinositides: From the Study of Sperm Flagellum

Takafumi Kawai, Yasushi Okamura

Frontiers in Physiology　Vol. 13　p. 1-5　2022/02/07　Research paper (scientific journal)

腎臓で機能するNa-Pi cotransporter SLC34A3のイオン輸送の仕組みの解明

周 俊先, 大河内 善史, 水谷 夏希, 塩崎 雄治, 瀬川 博子, 岡村 康司

日本生理学雑誌　Vol. 84　No. 1　p. 33-33　2022/02

Insight into the function of a unique voltage-sensor protein (TMEM266) and its short form in mouse cerebellum.

Kawai T, Narita H, Konno K, Akter S, Andriani R, Iwasaki H, Nishikawa S, Yokoi N, Fukata Y, Fukata M, Wiriyasermkul P, Kongpracha P, Nagamori S, Takao K, Miyakawa T, Abe M, Sakimura K, Watanabe M, Nakagawa A, Okamura Y

Biochem J. (in Press)　Vol. 479　No. 11　p. 1127-1145　2022　Research paper (scientific journal)

Interaction between S4 and the phosphatase domain mediates electrochemical coupling in voltage-sensing phosphatase, VSP

Mizutani N, Kawanabe A, Jinno Y, Narita H, Yonezawa T, Nakagawa A, Okamura Y

PNAS (in Press)　Vol. 119　No. 26　2022　Research paper (scientific journal)

Regulation of Neutrophil Functions by Hv1/VSOP Voltage-Gated Proton Channels

Yoshifumi Okochi, Yasushi Okamura

International Journal of Molecular Sciences　Vol. 22　No. 5　p. 2620-2620　2021/03/05　Research paper (scientific journal)

Engineering voltage sensing phosphatase (VSP).

Tsutsui H, Mizutani N, Okamura Y

Methods in Enzymology　Vol. 654　p. 85-114　2021/02　Research paper (scientific journal)

Heterologous functional expression of ascidian Nav1 channels and close relationship with the evolutionary ancestor of vertebrate Nav channels

Takafumi Kawai, Masaki Hashimoto, Natsuki Eguchi, Junko M. Nishino, Yuka Jinno, Risa Mori-Kreiner, Måns Aspåker, Daijiro Chiba, Yukio Ohtsuka, Akira Kawanabe, Atsuo S. Nishino, Yasushi Okamura

Journal of Biological Chemistry　Vol. 296　p. 100783-100783　2021/01　Research paper (scientific journal)

Heterogeneity of microglial proton channel in different brain regions and its relationship with aging.

Kawai T, Takao K, Akter S, Abe M, Sakimura K, Miyakawa T, Okamura Y

Journal of Neurachemistry　2021/01　Research paper (scientific journal)

The Slo3/Lrrc52 complex is sensitive to phosphoinositides.

Takafumi Kawai, Yasushi Okamura

Channels (Austin, Tex.)　Vol. 14　No. 1　p. 1-3　2020/12　Research paper (scientific journal)

Regulation of hepatic oxidative stress by voltage-gated proton channels (Hv1/VSOP) in Kupffer cells and its potential relationship with glucose metabolism.

Kawai T, Kayama K, Tatsumi S, Akter S, Miyawaki N, Okochi Y, Abe M, Sakimura K, Yamamoto H, Kihara S, Okamura Y

FASEB J.　Vol. 34　No. 12　p. 15805-15821　2020/11　Research paper (scientific journal)

TRPM5 Negatively Regulates Calcium-Dependent Responses in Lipopolysaccharide-Stimulated B Lymphocytes.

Taiki Sakaguchi, Ryu Okumura, Chisato Ono, Daisuke Okuzaki, Takafumi Kawai, Yoshifumi Okochi, Natsuko Tanimura, Mari Murakami, Hisako Kayama, Eiji Umemoto, Hidetaka Kioka, Tomohito Ohtani, Yasushi Sakata, Kensuke Miyake, Yasushi Okamura, Yoshihiro Baba, Kiyoshi Takeda

Cell reports　Vol. 31　No. 10　p. 107755-107755　2020/06/09　Research paper (scientific journal)

Engineering an enhanced voltage-sensing phosphatase.

Akira Kawanabe, Natsuki Mizutani, Onur K Polat, Tomoko Yonezawa, Takafumi Kawai, Masayuki X Mori, Yasushi Okamura

The Journal of general physiology　Vol. 152　No. 5　2020/05/04　Research paper (scientific journal)

Hv1/VSOP regulates neutrophil directional migration and ERK activity by tuning ROS production

Yoshifumi Okochi, Eiji Umemoto, Yasushi Okamura

Journal of Leukocyte Biology　Vol. 107　No. 5　p. 819-831　2020/05　Research paper (scientific journal)

Activation Mechanisms of Voltage Sensing Phosphatase

Akira KAWANABE, Kazuhisa NISHIZAWA, Yasushi OKAMURA

Seibutsu Butsuri　Vol. 60　No. 2　p. 105-107　2020　Research paper (scientific journal)

Functional analysis of a double-point mutation in the KCNJ2 gene identified in a family with Andersen-Tawil syndrome.

Shinobu Fukumura, Kosuke Yamauchi, Akira Kawanabe, Akiyo Yamamoto, Maki Nakaza, Tomoya Kubota, Shinsuke Kato, Ryogen Sasaki, Yasushi Okamura, Masanori P Takahashi

Journal of the neurological sciences　Vol. 407　p. 116521-116521　2019/12/15　Research paper (scientific journal)

Polarized PtdIns(4,5)P2 distribution mediated by a voltage-sensing phosphatase (VSP) regulates sperm motility.

Takafumi Kawai, Haruhiko Miyata, Hiroki Nakanishi, Souhei Sakata, Shin Morioka, Junko Sasaki, Masahiko Watanabe, Kenji Sakimura, Toyoshi Fujimoto, Takehiko Sasaki, Masahito Ikawa, Yasushi Okamura

Proceedings of the National Academy of Sciences of the United States of America　Vol. 116　No. 51　p. 26020-26028　2019/12　Research paper (scientific journal)

Distinct functional properties of two electrogenic isoforms of the SLC 34 Na‐Pi cotransporter

Natsuki Mizutani, Yoshifumi Okochi, Yasushi Okamura

Physiological Reports　Vol. 7　No. 14　2019/07　Research paper (scientific journal)

Analysis of membrane potential of phagosome in phagocytes

Yoshifumi Okochi, Hidekazu Tsutsui, Yasushi Okamura

2019/06　Research paper (other academic)

ホスフォイノシチドによるチャネル・トランスポーターの制御

岡村康司, 水谷夏希, 大河内善史

医学のあゆみ　Vol. 269　No. 13　p. 1108-1113　2019/06　Research paper (scientific journal)

NaV チャネル全史̶̶細菌からヒトまで̶̶

西野 敦雄, 岡村 康司

生化学　Vol. 91　No. 2　p. 1-14　2019/04

Real-time functional analysis of Hv1 channel in neutrophils: a new approach from zebrafish model.

Ratanayotha A, Kawai T, Okamura Y

American journal of physiology. Regulatory, integrative and comparative physiology　2019/04

Molecular mechanisms of coupling to voltage sensors in voltage-evoked cellular signals.

Yasushi Okamura, Yoshifumi Okochi

Proceedings of the Japan Academy. Series B, Physical and biological sciences　Vol. 95　No. 3　p. 111-135　2019/03　Research paper (scientific journal)

Hv1/VSOP voltage-gated proton channel inhibits migration in response to fMLF in neutrophils

Yoshifumi Okochi, Yasushi Okamura

学会発表　2019/03　Research paper (international conference proceedings)

Dynamic structural rearrangements and functional regulation of voltage-sensing phosphatase.

Sakata S, Okamura Y

The Journal of physiology　2019/01　Research paper (scientific journal)

The hydrophobic nature of a novel membrane interface regulates the enzyme activity of a voltage-sensing phosphatase

Akira Kawanabe, Masaki Hashimoto, Manami Nishizawa, Kazuhisa Nishizawa, Hirotaka Narita, Tomoko Yonezawa, Yuka Jinno, Souhei Sakata, Atsushi Nakagawa, Yasushi Okamura

eLife　Vol. 7　2018/11　Research paper (scientific journal)

遺伝学的検査により同定されたAndersen-Tawil症候群家系における新規遺伝子変異V296Fとその機能解析

山内 亨祐, 福村 忍, 川鍋 陽, 山本 晃代, 仲座 真希, 久保田 智哉, 加藤 辰輔, 佐々木 良元, 岡村 康司, 高橋 正紀

臨床神経生理学　Vol. 46　No. 5　p. 482-482　2018/10

Zn²⁺-Binding to the Voltage-Gated Proton Channel Hv1/VSOP.

Iwaki M, Takeshita K, Kondo HX, Kinoshita K, Okamura Y, Takano Y, Nakagawa A, Kandori H

The journal of physical chemistry. B　Vol. 122　No. 39　p. 9076-9080　2018/10　Research paper (scientific journal)

Voltage-Sensing Phosphatases: Biophysics, Physiology, and Molecular Engineering.

Okamura Y, Kawanabe A, Kawai T

Physiological reviews　Vol. 98　No. 4　p. 2097-2131　2018/10　Research paper (scientific journal)

Conservation of the Ca²⁺-permeability through the voltage sensor domain of mammalian CatSper subunit.

Arima H, Tsutsui H, Okamura Y

Channels (Austin, Tex.)　Vol. 12　No. 1　p. 240-248　2018/08　Research paper (scientific journal)

Tracking the sarcoplasmic reticulum membrane voltage in muscle with a FRET biosensor.

Sanchez C, Berthier C, Allard B, Perrot J, Bouvard C, Tsutsui H, Okamura Y, Jacquemond V

The Journal of general physiology　Vol. 150　No. 8　p. 1163-1177　2018/06　Research paper (scientific journal)

Induction of divalent cation permeability by heterologous expression of a voltage sensor domain.

Hiroki Arima, Hidekazu Tsutsui, Ayako Sakamoto, Manabu Yoshida, Yasushi Okamura

Biochimica et biophysica acta. Biomembranes　Vol. 1860　No. 5　p. 981-990　2018/05　Research paper (scientific journal)

Measurement o f membrane potential change in phagosome of phagocytes

Yoshifumi Okochi, Hidekazu Tsutsui, Yasushi Okamura

2018/03　Research paper (other academic)

電位依存性プロトンチャネルが肝臓の糖代謝に寄与する可能性について

香山建斗, 河合喬文, 辰巳翔基, 山本浩靖, 崎村建司, 木原進, 岡村康司

2017/11

マウス精子における電位依存性ホスファターゼの機能

河合喬文, 宮田治彦, 中西広樹, 坂田宗平, 大河内善史, 渡辺雅彦, 崎村建司, 佐々木雄彦, 伊川正人, 岡村康司

2017/11

電位依存性ホスファターゼVSP の膜近傍領域の役割

川鍋陽, 橋本真宜, 米澤智子, 神野有香, 坂田宗平, 岡村康司

2017/11

Evolutionary History of Voltage-Gated Sodium Channels

Nishino A, Okamura Y

In: Chahine M. (eds) Voltage-gated Sodium Channels: Structure, Function and Channelopathies. Handbook of Experimental Pharmacology (eBook)　2017/11

Coupling Mechanisms of Voltage-Sensing Phosphatase

Yasushi Okamura, Akira Kawanabe, Yuka Jinno, Souhei Sakata

2017/10

The role of histidine and carboxylate residues for zinc inhibition in the voltage-gated proton channel Hv1/VSOP

Masayo Iwaki, Kohei Takeshita, Hiroki Arima, Yasushi Okamura, Atsushi Nakagawa, Hideki Kandori

2017/09

Molecular dynamics study of kinetics of the voltage-gated proton channel VSOP/Hv1 under electric fields

Hiroko X. Kondo, Yasushige Yonezawa, Naoyuki Miyashita, Masayo Iwaki, Kohei Takeshita, Yuichiro Fujiwara, Matsuyuki Shirota, Kengo, Kinoshita, Yasushi Okamura, Atsushi Nakagawa, Hideki Kandori, Yu Takano

2017/09

Structural analysis of Voltage-sensing phosphatase (VSP) on the electrochemical coupling between the Voltage sensor domain and cytoplasmic phosphatase

Hirotaka Narita, Naoki Kanda, Yasushi Okamura, Atsushi Nakagawa

2017/09

電位依存性ホスファターゼVSPの酵素活性に対する膜近傍領域の役割

川鍋陽, 橋本真宜, 米澤智子, 神野有香, 坂田宗平, 岡村康司

2017/09

Development of a chemiluminescent voltage indicator applicable to brain activity recording in freely moving multiple mice

Shigenori Inagaki, Masakazu Agetsuma, Hidekazu Tsutsui, Shinya Ohara, Yoshiyuki Arai, Kazushi Suzuki, Yuka Jinno, Tomoki Matsuda, Toshio Iijima, Yasushi Okamura, Takeharu Nagai

2017/07

Unconventional role of voltage-gated proton channels (VSOP/Hv1) in regulation of microglial ROS production

Takafumi Kawai, Yoshifumi Okochi, Tomohiko Ozaki, Yoshio Imura, Schuichi Koizumi, Maya Yamazaki, Manabu Abe, Kenji Sakimura, Toshihide Yarnashitat, Yasushi Okamura

JOURNAL OF NEUROCHEMISTRY　Vol. 142　No. 5　p. 686-699　2017/06　Research paper (scientific journal)

Domain-to-domain coupling in voltage-sensing phosphatase.

Sakata S, Matsuda M, Kawanabe A, Okamura Y

Biophysics and physicobiology　Vol. 14　p. 85-97　2017/06　Research paper (scientific journal)

AMPA glutamate receptors are required for sensory-organ formation and morphogenesis in the basal chordate.

Shinobu Hirai, Kohji Hotta, Yoshihiro Kubo, Atsuo Nishino, Shigeo Okabe, Yasushi Okamura, Haruo Okado

Proceedings of the National Academy of Sciences of the United States of America　Vol. 114　No. 15　p. 3939-3944　2017/04　Research paper (scientific journal)

初代培養ミクログリアにおける電位依存性プロトンチャネルのダイナミクス

河合 喬文, 川村 名子, 小泉 修一, 阿部 学, 崎村 建司, 岡村 康司

学会発表　2017/03

Voltage-gated proton channel in zebrafish (DrHv1): from culture dish to living animal

Adisorn Ratanayotha, Takafumi Kawai, Yasushi Okamura

2017/03

カルシウムイオン透過性を持つ電位センサードメインの機能解析

有馬 大貴, 筒井 秀和, 岡村 康司

2017/03

マウス好中球においてHv1/VSOPはfMLPに対する走化性行動を抑制する

大河内 善史, 岡村 康司

2017/03

電位依存性ホスファターゼVSPの新規膜相互作用部位の重要性

川鍋 陽, 橋本 真宜, 米澤 智子, 神野 有香, 坂田 宗平, 岡村 康司

2017/03

電位依存性ホスファターゼの構造生物学的研究

中川 敦史, 成田 宏隆, 神田 直樹, 川鍋 陽, 岡村 康司

2017/03

電位依存性ホスファターゼにおける膜相互作用の動態と役割

岡村 康司, 川鍋 陽, 西澤 和久, 中川 敦史, 成田 宏隆, 坂田 宗平, 神野 有香

2017/03

Principle and biodiversity of voltage sensor domain in channels and enzyme

Yasushi Okamura

2017/02

Genetically encoded bioluminescent voltage indicator for multi-purpose use in wide range of bioimaging

Shigenori Inagaki, Hidekazu Tsutsui, Kazushi Suzuki, Masakazu Agetsuma, Yoshiyuki Arai, Yuka Jinno, Guirong Bai, Matthew J. Daniels, Yasushi Okamura, Tomoki Matsuda, Takeharu Nagai

SCIENTIFIC REPORTS　Vol. 7　2017/02　Research paper (scientific journal)

Voltage-gated proton channel in zebrafish: from culture dish to living animal

Ratanayotha A, Kawai T, Okamura Y

The Journal of Physiological Sciences　Vol. 67　2017

Comparison between mouse and sea urchin orthologs of voltage-gated proton channel suggests role of S3 segment in activation gating

Souhei Sakata, Nana Miyawaki, Thomas J. McCormack, Hiroki Arima, Akira Kawanabe, Nurdan Oezkucur, Tatsuki Kurokawa, Yuka Jinno, Yuichiro Fujiwara, Yasushi Okamura

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES　Vol. 1858　No. 12　p. 2972-2983　2016/12　Research paper (scientific journal)

膜電位非印加状態で開状態をとるVSOP/Hv1変異体から見る２量体間協調性

木村仁美, 持田理子, 渋村里美, 中川敦史, 岡村康司, 竹下浩平

2016/12

新規電位センサータンパク質VSOP2のX線結晶構造解析に向けて

西川翔士, 成田宏隆, 岡村康司, 中川敦史

2016/12

Characterization of Voltage-Gated Proton Channel in Zebrafish. (DrHv1)

Adisorn Ratanayotha, Takafumi Kawai, Yasushi Okamura

2016/11

電位依存性プロトンチャネルノックアウトマウスの代謝表現型解析

辰巳翔基, 河合喬文, 山本浩靖, 崎村建司, 木原進士, 岡村康司

2016/11

Direct observation og voltage-gated proton channels by high speed AFM

Hayato Yamashita, Akira Kawanabe, Yasushi Okamura, Msayuki Abe

2016/11

Development of a chemiluminescent voltage indicator applicable to brain activity recording in freely moving mice

Shigenori Inagaki, Masakazu Agetsuma, Hidekazu Tsutsui, Yoshiyuki Arai, Kazushi Suzuki, Yuka Jinno, Yasushi Okamura, Tomoki Matsuda, Takeharu Nagai

2016/11

The role of membrane interacting region of phosphatase domain in voltage-sensing phosphatase (VSP)

Akira Kawanabe, Masaki Hashimoto, Tomoko Yonezawa, Yuka Jinno, Souhei Sakata, Yasushi Okamura

2016/11

自由行動マウスの脳活動計測を可能にする化学発光膜電位センサーの開発

稲垣成矩, 揚妻正和, 筒井秀和, 新井由之, 鈴木和志, 神野有香, 岡村康司, 松田知己, 永井健治

2016/11

Crossroad of electricity and lipid signaling: voltage-sensing phosphoinositide phosphatase (VSP)

Yasushi Okamura, Akira Kawanabe, Souhei Sakata

2016/11

Metal binding to the voltage-gated proton channel VSOP studied by ATR-FTIR

Masayo Iwaki, Kohei Takeshita, Yasushi Okamura, Atushi Nakagawa, Hideki Kandori

2016/11

CatSperの電位センサードメインはカルシウムイオン透過性を持つ

有馬大貴, 筒井秀和, 吉田学, 岡村康司

2016/10

The common regulation of phosphatase activity of voltage-sensing phosphatase (VSP) and PTEN by conserved putatiｖe membrane interacting region

Akira Kawanabe, Tomoko Yonezawa, Yuka Jinno, Souhei Sakata, Yasushi Okamura

2016/09

Molecular mechanisms of voltage-sensing phosphatase, VSP

Yasushi Okamura

2016/09

膜の疎水領域でのリポクオリティ認識機構とナノなくドメインの解明

岡村康司

2016/07

Bidirectional regulation of ROS production by voltage-gated proton channels in microglia

Takafumi Kawai, Yoshifumi Okochi, Tomohiko Ozaki, Yoshio Imura, Kenji Sakimura, Schuichi Koizumi, Toshihide Yamashita, Yasushi Okamura

2016/07

How does voltage sensor domain regulate downstream effecter?: lesson from voltage-sensor domain proteins

Yasushi Okamura, Souhei Sakata, Akira Kawanabe, Yuichiro Fujiwara, Yuka Jinno

2016/07

Principle and biodiversity of voltage sensor domain proteins

Yasushi Okamura

2016/06

Regulation of ROS production by voltage-gated proton channels in mouse microglia

Yasushi Okamura

2016/06

Simple scheme of lipid enzyme can explain complex lives of phosphoinositides

Yasushi Okamura

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA　Vol. 113　No. 26　p. 7012-7014　2016/06　Research paper (scientific journal)

Voltage-dependent motion of the catalytic region of voltage-sensing phosphatase monitored by a fluorescent amino acid

Souhei Sakata, Yuka Jinno, Akira Kawanabe, Yasushi Okamura

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA　Vol. 113　No. 27　p. 7521-7526　2016/06　Research paper (scientific journal)

電位依存性ホスファターゼVSPとPTENに共通する膜との相互作用部位の重要性

川鍋陽, 米澤智子, 岡村康司

2016/05

Expression levels of ABCG2 on cord red blood cells and study of fetal anemia associated with anti-Jr(a)

Satoko Fujita, Hirokazu Kashiwagi, Takuji Tomimatsu, Shoichi Ito, Kazuya Mimura, Takeshi Kanagawa, Masayuki Endo, Tomomitsu Miyoshi, Yasushi Okamura, Yoshihiko Tani, Yoshiaki Tomiyama, Tadashi Kimura

TRANSFUSION　Vol. 56　No. 5　p. 1171-1181　2016/05　Research paper (scientific journal)

電位依存性プロトンチャネルにおけるプロトン透過機構について

岡村康司

生物物理　2016/05

Structural basis for the membrane association of ankyrinG via palmitoylation

Yuichiro Fujiwara, Hiroko X. Kondo, Matsuyuki Shirota, Megumi Kobayashi, Kohei Takeshita, Atsushi Nakagawa, Yasushi Okamura, Kengo Kinoshita

SCIENTIFIC REPORTS　Vol. 6　2016/04　Research paper (scientific journal)

Characterization of voltage-gated proton channel in zebrafish

Adisorn Ratanayota, Takafumi Kawai, Yasushi Okamura

2016/03

CatSperの電位センサードメインはカルシウム透過性を持つ

有馬大貴, 筒井秀和, 竹下浩平, 中川敦史, 坂本恵香, 吉田学, 岡村康司

2016/03

非天然アミノ酸Anapで検出された電位センサーの動き

筒井秀和, 神野有香, 坂田宗平, 岡村康司

2016/03

膜脂質と相互作用する可能性のある相同領域による電位依存性ホスファターゼVSPとPTENの機能制御

川鍋陽, 神野有香, 坂田宗平, 岡村康司

2016/03

好中球の走化性における電位依存性プロトンチャネルの役割

大河内善史, 岡村康司

2016/03

Direct Interaction between the Voltage Sensors Produces Cooperative Sustained Deactivation in Voltage-gated H+ Channel Dimers

Hiroko Okuda, Yasushige Yonezawa, Yu Takano, Yasushi Okamura, Yuichiro Fujiwara

JOURNAL OF BIOLOGICAL CHEMISTRY　Vol. 291　No. 11　p. 5935-5947　2016/03　Research paper (scientific journal)

CatSper has a Calcium-Permeable Voltage Sensor Domain

Hiroki Arima, Hidekazu Tsutsui, Kohei Takeshita, Atsushi Nakagawa, Ayako Sakamoto, Manabu Yoshida, Yasushi Okamura

BIOPHYSICAL JOURNAL　Vol. 110　No. 3　p. 114A-115A　2016/02　Research paper (scientific journal)

The voltage-gated proton channel Hv1/VSOP inhibits neutrophil granule release

Yoshifumi Okochi, Yasuaki Aratani, Hibret A. Adissu, Nana Miyawaki, Mari Sasaki, Kazuo Suzuki, Yasushi Okamura

JOURNAL OF LEUKOCYTE BIOLOGY　Vol. 99　No. 1　p. 7-19　2016/01　Research paper (scientific journal)

Effects of unsaturated fatty acids on the kinetics of voltage-gated proton channels heterologously expressed in cultured cells

Akira Kawanabe, Yasushi Okamura

JOURNAL OF PHYSIOLOGY-LONDON　Vol. 594　No. 3　p. 595-610　2016/01　Research paper (scientific journal)

複数の光遺伝学操作と組み合わせたイメージングと薬剤スクリーニングの可能性を広げる発光膜電位指示薬の開発

稲垣 成矩, 松田 知己, 新井 由之, 白 貴蓉, 神野 有香, 筒井 秀和, 岡村 康司, 永井 健治

日本生化学会大会・日本分子生物学会年会合同大会講演要旨集　Vol. 88回・38回　p. [4T21L-09(3P0901)]　2015/12

カルシウムイオン透過性を持つ電位センサードメインの機能解析

有馬大貴, 筒井秀和, 岡村康司

2015/10

How is VSP’s enzyme activity activated by intrinsic voltage sensor?

Yasushi Okamura

2015/10

電位依存性プロトンチャネル（VSOP）の結晶構造から考察するプロトン漏洩制御機構

竹下 浩平, 岡村 康司, 中川 敦史

生化学　Vol. 87　No. 5　p. 625-628　2015/10　Research paper (scientific journal)

[Structural insight into the regulation mechanism of proton leakage based on crystal structure of voltage-gated proton channel (VSOP)].

Takeshita K, Okamura Y, Nakagawa A

Seikagaku. The Journal of Japanese Biochemical Society　Vol. 87　No. 5　p. 625-628　2015/10

電位依存性プロトンチャネルの2量体と単量体間のゲーティング特性の違いを増大させる変異体の解析

川鍋陽, 岡村康司

2015/09

最小イオンチャネルHv1/VSOPによる貪食細胞の活性酸素産生の多重制御

岡村康司

2015/09

カルシウムイオン透過性を持つ電位センサードメインの機能解析

有馬大貴, 筒井秀和, 岡村康司

2015/09

Molecular mechanisms of voltage sensing phosphatase, VSP

Yasushi Okamura

2015/08

電位依存性プロトンチャネルによるミクログリア活性酸素産生の制御

河合 喬文, 大河内 善史, 井村 誉史雄, 崎村 建司, 小泉 修一, 岡村 康司

2015/07

Fine tuning of neutrophil activities by the voltage-gated proton channel, Hv1

Yasushi Okamura

2015/06

Determinants of activation rate of voltage-gated proton channel revealed by chimeric constructs between two orthologs

Yasushi Okamura

2015/06

NIPS-JP symposium: Cutting-edge approaches towards the functioning mechanisms of membrane proteins

Yoshihiro Kubo, Yasushi Okamura

JOURNAL OF PHYSIOLOGY-LONDON　Vol. 593　No. 12　p. 2551-2552　2015/06

Gating mechanisms of voltage-gated proton channels.

Okamura Y, Fujiwara Y, Sakata S

Annual Reviews of Biochemistry　2015/05　Research paper (scientific journal)

電位センサー機能の多様性と共通原理について

岡村康司

2015/04

Mapping of sites facing aqueous environment of voltage-gated proton channel at resting state: a study with PEGylation protection.

Kurokawa T, Okamura Y

Biochimica et biophysica acta　Vol. 1838　No. 1 Pt B　p. 382-387　2014/10　Research paper (scientific journal)

Rapid evaluation of a protein-based voltage probe using a field-induced membrane potential change

Hidekazu Tsutsui, Yuka Jinno, Akiko Tomita, Yasushi Okamura

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES　Vol. 1838　No. 7　p. 1730-1737　2014/07　Research paper (scientific journal)

Potential Role of Voltage-Sensing Phosphatases in Regulation of Cell Structure Through the Production of PI(3,4)P-2

Shinji Yamaguchi, Tatsuki Kurokawa, Ikuko Taira, Naoya Aoki, Souhei Sakata, Yasushi Okamura, Koichi J. Homma

JOURNAL OF CELLULAR PHYSIOLOGY　Vol. 229　No. 4　p. 422-433　2014/04　Research paper (scientific journal)

Long alpha helices projecting from the membrane as the dimer interface in the voltage-gated H+ channel

Yuichiro Fujiwara, Tatsuki Kurokawa, Yasushi Okamura

JOURNAL OF GENERAL PHYSIOLOGY　Vol. 143　No. 3　p. 377-386　2014/03　Research paper (scientific journal)

A Kir3.4 mutation causes Andersen-Tawil syndrome by an inhibitory effect on Kir2.1

Yosuke Kokunai, Tomohiko Nakata, Mitsuru Furuta, Souhei Sakata, Hiromi Kimura, Takeshi Aiba, Masao Yoshinaga, Yusuke Osaki, Masayuki Nakamori, Hideki Itoh, Takako Sato, Tomoya Kubota, Kazushige Kadota, Katsuro Shindo, Hideki Mochizuki, Wataru Shimizu, Minoru Horie, Yasushi Okamura, Kinji Ohno, Masanori P. Takahashi

NEUROLOGY　Vol. 82　No. 12　p. 1058-1064　2014/03　Research paper (scientific journal)

X-ray crystal structure of voltage-gated proton channel

Kohei Takeshita, Souhei Sakata, Eiki Yamashita, Yuichiro Fujiwara, Akira Kawanabe, Tatsuki Kurokawa, Yoshifumi Okochi, Makoto Matsuda, Hirotaka Narita, Yasushi Okamura, Atsushi Nakagawa

NATURE STRUCTURAL & MOLECULAR BIOLOGY　Vol. 21　No. 4　p. 352-U170　2014/03　Research paper (scientific journal)

PLC-mediated PI(4,5)P-2 hydrolysis regulates activation and inactivation of TRPC6/7 channels

Kyohei Itsuki, Yuko Imai, Hideharu Hase, Yasushi Okamura, Ryuji Inoue, Masayuki X. Mori

JOURNAL OF GENERAL PHYSIOLOGY　Vol. 143　No. 2　p. 183-201　2014/02　Research paper (scientific journal)

3P296 Genetically-encoded chemiluminescent voltage indicator applicable in conjunction with multiple optogenetic tools(27. Bioimaging,Poster,The 52nd Annual Meeting of the Biophysical Society of Japan(BSJ2014))

Inagaki Shigenori, Matsuda Tomoki, Arai Yoshiyuki, Jinno Yuka, Tsutsui hidekazu, Okamura Yasushi, Nagai Takeharu

Seibutsu Butsuri　Vol. 54　No. 1　2014

1P219 Gating charge movement of the voltage-gated H^+ channel(13C. Biological & Artificial membrane: Excitation & Channels,Poster,The 52nd Annual Meeting of the Biophysical Society of Japan(BSJ2014))

Fujiwara Yuichiro, Okamura Yasushi

Seibutsu Butsuri　Vol. 54　No. 1　2014

3P012 Preliminary study of voltage-gated proton channel in activated state for X-ray crystallography(01A. Protein: Structure,Poster,The 52nd Annual Meeting of the Biophysical Society of Japan(BSJ2014))

Kumano Wataru, Takeshita Kohei, Emura Kohta, Yamashita Eiki, Okamura Yasushi, Nakagawa Atsushi

Seibutsu Butsuri　Vol. 54　No. 1　2014

Mapping of sites facing aqueous environment of voltage-gated proton channel at resting state: A study with PEGylation protection

Tatsuki Kurokawa, Yasushi Okamura

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES　Vol. 1838　No. 1　p. 382-387　2014/01　Research paper (scientific journal)

Long Alpha-Helices Projecting from the Membrane as the Dimer Interface in the Voltage-Gated H+ Channel

Yuichiro Fujiwara, Tatsuki Kurokawa, Yasushi Okamura

BIOPHYSICAL JOURNAL　Vol. 106　No. 2　p. 745A-745A　2014/01

Expression of the voltage-sensing phosphatase gene in the chick embryonic tissues and in the adult cerebellum

Shinji Yamaguchi, Naoya Aoki, Takaaki Kitajima, Yasushi Okamura, Koichi J Homma

Communicative and Integrative Biology　Vol. 7　No. 5　2014　Research paper (scientific journal)

Functional diversity of voltage-sensing phosphatases in two urodele amphibians

Joshua Mutua, Yuka Jinno, Souhei Sakata, Yoshifumi Okochi, Shuichi Ueno, Hidekazu Tsutsui, Takafumi Kawai, Yasuhiro Iwao, Yasushi Okamura

Physiological Reports　Vol. 2　No. 7　2014　Research paper (scientific journal)

Temperature-Sensitive Gating of Voltage-Gated Proton Channels

Yuichiro Fujiwara, Yasushi Okamura

Current Topics in Membranes　Vol. 74　No. 1　p. 259-292　2014　Research paper (scientific journal)

Structural characteristics of the redox-sensing coiled coil in the voltage-gated H+ channel

Yuichiro Fujiwara, Kohei Takeshita, Atsushi Nakagawa, Yasushi Okamura

Journal of Biological Chemistry　Vol. 288　No. 25　p. 17968-17975　2013/06/21　Research paper (scientific journal)

10.1016/B978-0-12-800181-3.00010-5.

Fujiwara Y, Kurokawa T, Takeshita K, Kobayashi M, Okochi Y, Nakagawa A, Okamura Y

Spring-8 Research Fronteiers.　2013/05　Research paper (scientific journal)

"Neural development in simpler embryos: A retrospective of Dr. Kunitaro Takahashi's work"

William J. Moody, Yasushi Okamura

Neuroscience Research　Vol. 75　No. 3　p. 167-170　2013/03　Research paper (scientific journal)

Subcellular localization of voltage-gated proton channels in primary cultured microglia.

Kawai T, Imura Y, Koizumi S, Okochi Y, Sakimura K, Okamura Y

2013/03　Research paper (international conference proceedings)

The optimization of the electrophysiological characterization of the voltage-gated proton channel on the artificial membrane.

Kawanabe A, Okamura Y

2013/03　Research paper (international conference proceedings)

Phosphatase activity of VSP is graded in a reflection of the sequential motion of the voltage sensor.

Sakata S, Okamura Y

2013/03　Research paper (international conference proceedings)

Physiological genomics of amphibian VSP: a potential molecular mechanism of electrical block of fertilization in vertebrates.

Mutua J, Jinno Y, Ueno S, Sakata S, Okochi Y, Tsutsui H, Iwao Y, Jaffe L, Okamura Y

2013/03　Research paper (international conference proceedings)

Rapid evaluation of optical voltage reporters using field-induced transmembrane potential response.

Tsutsui H, Okamura Y

2013/03　Research paper (international conference proceedings)

Substrate specificity of the voltage-sensing phosphatase (VSP) changes with membrane potential.

Kurokawa T, Takasuga S, Sakata S, Yamaguchi S, Shigeo H, Homma K, Sasaki T, Okamura Y

2013/03　Research paper (international conference proceedings)

How excited to talk with PI?: Lesson from voltage-sensing phosphatase.

Okamura Y

2013/03　Research paper (international conference proceedings)

Autoimmune disorder phenotypes in Hvcn1-deficient mice

Mari Sasaki, Akihiro Tojo, Yoshifumi Okochi, Nana Miyawaki, Daisuke Kamimura, Akihito Yamaguchi, Masaaki Murakami, Yasushi Okamura

BIOCHEMICAL JOURNAL　Vol. 450　No. 2　p. 295-301　2013/03　Research paper (scientific journal)

PIP2 dynamics underlying muscarinic or vasopressin receptor-activated TRPC3 C6 and C7 currents.

Itsuki K, Imai Y, Okamura Y, Inoue R, Mori, MX

2013/02　Research paper (international conference proceedings)

Calcium transients in muscle fibers expressing voltage-sensitive phosphoinositide phosphatases.

Loustau T, Legrand C, Berthier C, Okamura Y, Jacquemond V

2013/02　Research paper (international conference proceedings)

Graded tuning of phosphatase activity of VSP coupled with the intermediate state of the voltage sensor.

Sakata S, Okamura Y

2013/02　Research paper (international conference proceedings)

Gating of the designed trimeric/tetrameric voltage-gated H+ channel

Yuichiro Fujiwara, Tatsuki Kurokawa, Kohei Takeshita, Atsushi Nakagawa, H. Peter Larsson, Yasushi Okamura

JOURNAL OF PHYSIOLOGY-LONDON　Vol. 591　No. 3　p. 627-640　2013/02　Research paper (scientific journal)

Subcellular localization of voltage-gated proton channels in primary cultured microglia

Takafumi Kawai, Yoshio Imura, Shuichi Koizumi, Yoshifumi Okochi, Kenji Sakimura, Yasushi Okamura

JOURNAL OF PHYSIOLOGICAL SCIENCES　Vol. 63　p. S243-S243　2013

Physiological Genomics of Amphibian VSP : A Potential Molecular Mechanism of Electrical Block of Fertilization in Vertebrates

Joshua Mutunga Mutua, Yuka Jinno, Shuichi Ueno, Souhei Sakata, Yoshifumi Okochi, Hidekazu Tsutsui, Yasuhiro Iwao, Laurinda Jaffe, Yasushi Okamura

JOURNAL OF PHYSIOLOGICAL SCIENCES　Vol. 63　p. S251-S251　2013

Structural bases of the gating regulation in the voltage-gated H+ channel.

Fujiwara Y, Kurokawa T, Okamura Y

2013/01

Molecular mechanisms of voltage-sensor domain proteins.

Yasushi Okamura, Tatsuki Kurokawa, Morten H.H Norholm, Gunnar von Heijne, Declan Dolye, Jack E. Dixon

2012/12　Research paper (international conference proceedings)

3 ' Phosphatase activity toward phosphatidylinositol 3,4-bisphosphate [PI(3,4)P-2] by voltage-sensing phosphatase (VSP)

Tatsuki Kurokawa, Shunsuke Takasuga, Souhei Sakata, Shinji Yamaguchi, Shigeo Horie, Koichi J. Homma, Takehiko Sasaki, Yasushi Okamura

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA　Vol. 109　No. 25　p. 10089-10094　2012/12　Research paper (international conference proceedings)

Molecular properties of voltage-sensing phosphatases and applications to molecular tools.

Okamura Y, Tsutsui H

2012/11　Research paper (international conference proceedings)

電位依存性プロトンチャネルのゲーティングを制御する分子構造

藤原 祐一郎, 黒川 竜紀, 竹下浩平, 中川 敦史, 岡村 康司

2012/09

Secret lives of voltage-sensing phosphatases.

Yasushi Okamura

2012/07

ミクログリアの活性酸素産生と亜鉛シグナル調節因子としてのプロトチャネル

岡村 康司

2012/07

電位感受性ホスファターゼVSPを分子ツールとして用いたイノシトールリン脂質シグナル伝達の解析

岡村 康司

2012/06

The cytoplasmic coiled-coil mediates cooperative gating temperature sensitivity in the voltage-gated H+ channel Hv1

Yuichiro Fujiwara, Tatsuki Kurokawa, Kohei Takeshita, Megumi Kobayashi, Yoshifumi Okochi, Atsushi Nakagawa, Yasushi Okamura

NATURE COMMUNICATIONS　Vol. 3　2012/05　Research paper (scientific journal)

Voltage-sensing phosphatase reveals temporal regulation of TRPC3/C6/C7 channels by membrane phosphoinositides

Kyohei Itsuki, Yuko Imai, Yasushi Okamura, Kihachiro Abe, Ryuji Inoue, Masayuki X. Mori

CHANNELS　Vol. 6　No. 3　p. 206-209　2012/05　Research paper (scientific journal)

PIP2-PLC-DAGシグナルと連動したTRPC3/C6/C7チャネルの自律的制御機構

森誠之, 今井裕子, 齋郷平, 岡村康司, 井上隆司

2012/03　Research paper (international conference proceedings)

VSP による細胞形態制御

岡村康司, 山口真二, 黒川竜紀, 坂田宗平, 青木直哉, 平郁子, 本間光一

2012/03　Research paper (international conference proceedings)

DAG 活性化型TRPC チャネルにおける電流、細胞内Ca2＋とPI（4,5）P2 の相関

齊郷平, 今井裕子, 岡村康司, 井上隆司, 森誠之

2012/03　Research paper (international conference proceedings)

人工膜に再構成した電位依存性プロトンチャネルVSOP のチャネル活性

川鍋陽, 岡村康司

2012/03　Research paper (international conference proceedings)

電位依存性ホスファターゼ（VSP）の電位センサーの変異体における電位依存的酵素活性の計測

坂田宗平, ホサインモハマド, 岡村康司

2012/03　Research paper (international conference proceedings)

3,4 量体型へ人工的にデザインした電位依存性プロトンチャネルのゲーティング

藤原祐一郎, 黒川竜紀, 岡村康司

2012/03

KCNE3 によるゲーティング修飾におけるKCNQ1 チャネルS1 セグメントの機能的役割

中條浩一, 西野敦雄, 岡村康司, 久保義弘

2012/03　Research paper (international conference proceedings)

電位センサードメイン蛋白の構造基盤：モジュールの共役による分子機能

岡村康司, 藤原祐一郎, 大河内善史, 筒井秀和, 坂田宗平, 川鍋陽, 中川敦史, 竹下浩平, 松田真

2012/03

生命における電気信号の秘密を探る

岡村康司, 藤原祐一郎, 大河内善史, 筒井秀和, 坂田宗平, 川鍋陽, 中川敦史, 竹下浩平, 松田真

2012/03

感染防御機構における電位依存性プロトンチャネルVSOP の役割の解析

大河内善史, 荒谷康昭, 宮脇奈那, 佐々木真理, 鈴木和男, 岡村康司

2012/03　Research paper (international conference proceedings)

細胞膜たんぱく質による膜電位変化のセンシングと情報転換.

岡村 康司

2012/02

A self-limiting regulation of vasoconstrictor-activated TRPC3/C6/C7 channels coupled to PI(4,5)P 2-diacylglycerol signalling

Yuko Imai, Kyohei Itsuki, Yasushi Okamura, Ryuji Inoue, Masayuki X. Mori

Journal of Physiology　Vol. 590　No. 5　p. 1101-1119　2012/02　Research paper (scientific journal)

Unusual Features of Chick VSP and its Potential Role in Regulation of Cell Structure

Yasushi Okamura, Tatsuki Kurokawa, Shinji Yamaguchi, Naoya Aoki, Ikuko Taira, Souhei Sakata, Koichi Homma

BIOPHYSICAL JOURNAL　Vol. 102　No. 3　p. 37A-37A　2012/02

Ci-KCNQ1, an Ortholog of Vertebrate KCNQ1 from Ciona Intestinalis, has Revealed that KCNE1 and KCNE3 Utilize Different Domains of KCNQ1 for the Modulation of Gating

Koichi Nakajo, Atsuo Nishino, Yasushi Okamura, Yoshihiro Kubo

BIOPHYSICAL JOURNAL　Vol. 102　No. 3　p. 133A-133A　2012/02　Research paper (international conference proceedings)

Voltage gated proton channels

Y. Okamura

Comprehensive Biophysics　Vol. 6　p. 199-222　2012　Part of collection (book)

Cytoplasmic Coiled-Coil Mediates the Gating Coupling and the Temperature Sensitivity in the Voltage-gated H+ Channel.

藤原祐一郎, 黒川竜紀, 竹下浩平, 小林恵, 中川敦史, 岡村康司

2012/01

Visualizing voltage dynamics in Zebrafish heart

TSUTSUI Hidekazu, HIGASHIJIMA Shin-ichi, MIYAWAKI Atsushi, OKAMURA Yasushi

Folia Pharmacologica Japonica　Vol. 138　No. 6　p. 234-238　2011/12/01

A self-limiting regulation of vasoconstrictor-activated TRPC3/C6/C7 channels coupled to PI(4,5)P2-diacylglycerol signalling

Yuko Imai, Kyohei Itsuki, Yasushi Okamura, Ryuji Inoue, Masayuki X. Mori

JOURNAL OF PHYSIOLOGY-LONDON　Vol. 590　No. 5　p. 1101-1119　2011/12　Research paper (scientific journal)

Molecular mechanisms and potential biological roles ofvoltage-sensing phosphoinositide phosphatases.

Yasushi Okamura, Tatsuki Kurokawa, Souhei Sakata, Hidekazu Tsutsui, Takehiko Sasaki

2011/11

KCNQ1 subdomains involved in KCNE modulation revealed by an invertebrate KCNQ1 orthologue

Koichi Nakajo, Atsuo Nishino, Yasushi Okamura, Yoshihiro Kubo

JOURNAL OF GENERAL PHYSIOLOGY　Vol. 138　No. 5　p. 521-535　2011/11　Research paper (scientific journal)

感染防御機構における電位依存性プロトンチャネルVSOP の役割の解析

大河内善史, 荒谷康昭, 宮脇奈那, 佐々木真理, 鈴木和男, 岡村康司

2011/10

Characterizations of chick voltage-sensing phosphatase and its possible role in regulation of cell structure

Yasushi Okamura, Shinji Yamaguchi, Ikuko Taira, Tatsuki Kurokawa, Naoya Aoki, Souhei Sakata, Koichi J. Homma

2011/09

プロトンによる高次生命機能の制御とその分子機構

岡村 康司

2011/09

Characterizations of chick voltage-sensing phosphatase

Yasushi Okamura, Tatsuki Kurokawa, Souhei Sakata, Shinji Yamaguchi, Naoya Aoki, Taira Ikuko, Kouichi Homma

2011/09　Research paper (international conference proceedings)

電位依存性ホスファターゼVSPの作動原理：基質特異性とオルソログ分子の解析

黒川 竜紀, 坂田 宗平, 岡村 康司

2011/09

The physicochemical analysis for the voltage-gated proton channel

Akira Kawanabe, Tetsuya Fukuda, Hideki Kandori, Yasushi Okamura

2011/09

Crystal Structure of the Cytoplasmic Phosphatase and Tensin Homolog (PTEN)-like Region of Ciona intestinalis Voltage-sensing Phosphatase Provides Insight into Substrate Specificity and Redox Regulation of the Phosphoinositide Phosphatase Activity

Makoto Matsuda, Kohei Takeshita, Tatsuki Kurokawa, Souhei Sakata, Mamoru Suzuki, Eiki Yamashita, Yasushi Okamura, Atsushi Nakagawa

JOURNAL OF BIOLOGICAL CHEMISTRY　Vol. 286　No. 26　p. 23368-23377　2011/07　Research paper (scientific journal)

電位依存性プロトンチャネルの2量体会合はチャネルの温度感受性を制御する

藤原 祐一郎, 黒川竜紀, 竹下浩平, 小林 恵, 中 川 敦史, 岡村 康司

2011/06

VSOP1/Hv1 プロトンチャネル遺伝子欠損マウスの腎組織病変

藤乗 嗣泰, 衣笠 哲史, 大河内 善史, 佐々木 真理, 岡村 康司

2011/06

Voltage Sensitive Phosphoinositide Phosphatases of Xenopus: Their Tissue Distribution and Voltage Dependence

William J. Ratzan, Alexei V. Evsikov, Yasushi Okamura, Laurinda A. Jaffe

JOURNAL OF CELLULAR PHYSIOLOGY　Vol. 226　No. 11　p. 2740-2746　2011/05　Research paper (scientific journal)

Coupling of the phosphatase activity of Ci-VSP to its voltage sensor activity over the entire range of voltage sensitivity

Souhei Sakata, Md Israil Hossain, Yasushi Okamura

JOURNAL OF PHYSIOLOGY-LONDON　Vol. 589　No. 11　p. 2687-2705　2011/04　Research paper (scientific journal)

Regulation of ROS production by voltage-gated proton channel, VSOP, in phagocytes.

Yoshifumi Okochi, Yasushi Okamura, Tsukasa Kawahara

2011/03

Molecular basis of substrate specificity of voltage-sensing phosphatase VSP

Tatsuki Kurokawa, Yasushi Okamura

2011/03

Voltage-sensing phosphatase: mechanism and applications.

岡村 康司

2011/03

Modeling of the voltage-dependent change of the fluorescence of Ptdlns(4,5)P2-binding GFP upon the activities of voltage-sensing phosphatase, Ci-VSP

Souhei Sakata, Yasushi Okamura

2011/03

Modeling of the voltage-dependent change of the fluorescence of Ptdlns(4,5)P2-binding GFP upon the activities of voltage-sensing phosphatase, Ci-VSP

Souhei Sakata, Yasushi Okamura

2011/03

Molecular basis of substrate specificity of voltage-sensing phosphatase VSP

Tatsuki Kurokawa, Yasushi Okamura

2011/03　Research paper (international conference proceedings)

Gene expression profile of Ci-VSP in juveniles and adult blood cells of ascidian

Michio Ogasawara, Mari Sasaki, Noriko Nakazawa, Atsuo Nishino, Yasushi Okamura

GENE EXPRESSION PATTERNS　Vol. 11　No. 3-4　p. 233-238　2011/03　Research paper (scientific journal)

電位センサータンパクから見た、膜電位ー化学関連の機構と役割

岡村 康司

2011/02

Mechanisms of Voltage Sensor Domain and Voltage-Gated Proton Channel

Kurokawa Tatsuki, Okamura Yasushi

Vol. 51　No. 2　p. 72-75　2011/02　Research paper (scientific journal)

Voltage-Sensing Phosphatase: Its Molecular Relationship With PTEN

Yasushi Okamura, Jack E. Dixon

PHYSIOLOGY　Vol. 26　No. 1　p. 6-13　2011/02　Research paper (scientific journal)

A mechanism for graded motor control encoded in the channel properties of the muscle ACh receptor

Atsuo Nishino, Shoji A. Baba, Yasushi Okamura

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA　Vol. 108　No. 6　p. 2599-2604　2011/01　Research paper (scientific journal)

電位依存性ホスファターゼVSPの動作原理

岡村 康司

2010/12

A global synergy of ions and voltage?

Yasushi Okamura

JOURNAL OF PHYSIOLOGY-LONDON　Vol. 588　No. 23　p. 4649-4649　2010/11　Research paper (scientific journal)

膜電位依存性ホスファターゼCi-VSPの電位依存的な酵素活性の計測とモデリング

坂田宗平, 岡村康司

2010/10

電位依存性プロトンチャネルにおけるS4のトポロジー解析

黒川竜紀, 岡村康司

2010/09　Research paper (international conference proceedings)

電位依存性プロトンチャネル細胞内領域の結晶構造と機能的意義

藤原祐一郎, 岡村康司

2010/09

Visualizing voltage dynamics in zebrafish heart

Hidekazu Tsutsui, Shin-ichi Higashijima, Atsushi Miyawaki, Yasushi Okamura

JOURNAL OF PHYSIOLOGY-LONDON　Vol. 588　No. 12　p. 2017-2021　2010/06　Research paper (scientific journal)

acute dephosphorylation of PIPs leads to tranient inactivation of the TRPC6 channel

Yuko Imai, Masayuki Mori, Yasushi Okamura, Ryuji Inoue

2010/05

Parallel saturation of enzyme activity and voltage sensor movement in the voltage-sensing phosphatase, VSP.

Souhei Sakata, Yasushi Okamura

2010/05

Physiological genomics of voltage-sensing phosphatase.

Yasushi Okamura, Tatsuki Kurokawa, Souhei Sakata, Ikuko Fuji-Taira, Yoshifumi Okochi, Shinji Yamaguchi, Michio Ogasawara, Koichi Homma

2010/05

Topology of S4-like segment of the voltage-gated proton channel.

Tatsuki Kurokawa, Yasushi Okamura

2010/05　Research paper (international conference proceedings)

Single or double? Think zinc!

Yasushi Okamura

JOURNAL OF PHYSIOLOGY-LONDON　Vol. 588　No. 11　p. 1803-1804　2010/05　Research paper (scientific journal)

LIPIDS PI couples voltage to catalysis

Yasushi Okamura

NATURE CHEMICAL BIOLOGY　Vol. 6　No. 5　p. 315-316　2010/05　Research paper (scientific journal)

Modeling of the voltage-dependent change of the fluorescence of Ptdlns(4,5)P₂-binding GFP upon the activities of voltage-sensing phosphatase, Ci-VSP

Souhei Sakata

2010/03

Molecular basis of substrate specificity of voltage-sensing phosphatase VSP

Tatsuki Kurokawa, Yasushi Okamura

2010/03　Research paper (international conference proceedings)

The role of voltage-gated proton channel in phagocytes

2010/01

Membrane Topology of S4 of the Mouse Voltage-Gated Proton Channel

Souhei Sakata, Tatsuki Kurokawa, Morten Norholm, Masahiro Takagi, Yoshifumi Okochi, Gunnar von Heijne, Yasushi Okamura

BIOPHYSICAL JOURNAL　Vol. 98　No. 3　p. 539A-539A　2010/01　Research paper (scientific journal)

VSOP/Hv1 Proton Channels Sustain Superoxide Production, Calcium Entry, and Cell Migration by Limiting the Depolarization and Acidification of Activated Neutrophils

Antoun El Chemaly, Yoshifumi Okochi, Mari Sasaki, Serge Arnaudeau, Yasushi Okamura, Nicolas Demaurex

BIOPHYSICAL JOURNAL　Vol. 98　No. 3　p. 709A-709A　2010/01　Research paper (international conference proceedings)

VSOP/Hv1 proton channels sustain calcium entry, neutrophil migration, and superoxide production by limiting cell depolarization and acidification

Antoun El Chemaly, Yoshifumi Okochi, Mari Sasaki, Serge Arnaudeau, Yasushi Okamura, Nicolas Demaurex

JOURNAL OF EXPERIMENTAL MEDICINE　Vol. 207　No. 1　p. 129-139　2010/01　Research paper (scientific journal)

A glycine receptor is involved in the organization of swimming movements in an invertebrate chordate

Atsuo Nishino, Yasushi Okamura, Stefania Piscopo, Euan R. Brown

BMC NEUROSCIENCE　Vol. 11　2010/01　Research paper (scientific journal)

VSOP/Hv1 proton channels sustain calcium entry, neutrophil migration, and superoxide production by limiting cell depolarization and acidification

Antoun El Chemaly, Yoshifumi Okochi, Mari Sasaki, Serge Arnaudeau, Yasushi Okamura, Nicolas Demaurex

JOURNAL OF EXPERIMENTAL MEDICINE　Vol. 207　No. 1　p. 129-139　2010/01　Research paper (scientific journal)

A glycine receptor is involved in the organization of swimming movements in an invertebrate chordate

Atsuo Nishino, Yasushi Okamura, Stefania Piscopo, Euan R. Brown

BMC NEUROSCIENCE　Vol. 11　2010/01　Research paper (scientific journal)

培養細胞 PEGylation-protection法の確立と電位依存性プロトンチャネル(mVSOP/Hv1)におけるS4の役割と解析

黒川竜紀, 岡村康司

2009/12

Functionality of the voltage-gated proton channel truncated in S4

Souhei Sakata, Tatsuki Kurokawa, Morten H. H. Norholm, Masahiro Takagi, Yoshifumi Okochi, Gunnar von Heijne, Yasushi Okamura

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA　Vol. 107　No. 5　p. 2313-2318　2009/12　Research paper (scientific journal)

Avian voltage-sensor containing phosphatase provokes the morphological changes in fibroblasts by its phosphatase activity

Fujii-Taira I, Yamaguchi S, Yamada M, Kamigaki H, Kurokawa T, Okamura Y, Homma KJ

2009/10　Research paper (international conference proceedings)

Electrical manipulation of phosphatidylinositol lipids signaling by voltage sensitive phosphatase in living cells

Sato M, Okamura Y, Ueda M

2009/10　Research paper (international conference proceedings)

ホヤゲノムから見出された電位センサー蛋白の動作原理と応用

岡村康司

2009/10

How are axon initial segments evolved?

Okamura, Y

2009/09　Research paper (international conference proceedings)

Sensing membrane voltage with voltage sensitive phosphatase and new coral fluorescence proteins.

Hidekazu Tsutsui, Satoshi Karasawa, Atsushi Miyawaki, Yasushi Okamura

NEUROSCIENCE RESEARCH　Vol. 65　p. S18-S18　2009/09　Research paper (scientific journal)

Mechanisms and physiological roles of voltage-sensor domain proteins

Okamura Y

2009/08　Research paper (international conference proceedings)

2009 Harbin Conference on Ion Channels in Technology and Drug DiscoveryMechanisms of the voltage-sensor domain proteins

Okamura Y, Kurokawa T, Sakata S, Takagi M

2009/07　Research paper (international conference proceedings)

Mechanisms and roles of voltage-sensing proteins without pore structure

Okamura Y

2009/07　Research paper (international conference proceedings)

Analyses of voltage-gated proton channel, VSOP,in phagocytes

Yoshifumi Okochi, Mari Sasaki, Yasushi Okamura

J. Physiol. Sci.　2009/07　Research paper (international conference proceedings)

Membrane potential measurements with engineered fret sensor

Hidekazu Tsutsui, Satoshi Karasawa, Atsushi Miyawaki, Yasushi Okamura

J. Physiol. Sci.　2009/07　Research paper (international conference proceedings)

Voltage-dependent phosphatase activities of Ci-VSP at high membrane potential

Souhei Sakata, Israil Mohammed Hossain, Yasushi Okamura

J. Physiol. Sci.　2009/07　Research paper (international conference proceedings)

The role of c-terminal cytoplasmic regions in dimerization of voltage-gated proton channel.

Tatsuki Kurokawa, Yoshifumi Okochi, Yasushi Okamura

J. Physiol. Sci.　2009/07　Research paper (international conference proceedings)

Alteration of cellular phosphoinositides by voltage-sensing phosphatases

Yasushi Okamura, Md. Israil Hossain

J.Physiol.Sci.　2009/07　Research paper (international conference proceedings)

Mechanisms of physiological roles of votlage sensing proteins without pore structure"

Yasushi Okamura

J. Physiol. Sci.　2009/07　Research paper (international conference proceedings)

KCNE1 MODULATES KCNQ1 THROUGH SPECIFIC AMINO ACID RESIDUES IN THE PORE REGION

Koichi Nakajo, Atsuo Nishino, Yasushi Okamura, Yoshihiro Kubo

JOURNAL OF PHYSIOLOGICAL SCIENCES　Vol. 59　p. 255-255　2009/07　Research paper (international conference proceedings)

Hv1 PROTON CHANNELS SUSTAIN SUPEROXIDE PRODUCTION AND CALCIUM SIGNALING IN NEUTROPHILS

Antoun El Chemaly, Yoshifumi Okochi, Mari Sasaki, Serge Arnaudeau, Yasushi Okamura, Nicolas Demaurex

JOURNAL OF PHYSIOLOGICAL SCIENCES　Vol. 59　p. 401-401　2009/07　Research paper (international conference proceedings)

Nicotinic acetylcholine receptors in Ciona larval muscle and their physiological roles in shaping the swimming form

Nishino A, Baba S, Okamura Y

2009/06　Research paper (international conference proceedings)

Novel roles of voltage sensor domain discovered from ascidian genome: voltage-sensing phosphatase (VSP) and voltage-gated proton channel (VSOP/Hv1)

Sakata S, Okamura Y

2009/06　Research paper (international conference proceedings)

PI couples voltage to catalysis.

Okamura Y

Nature Chem Biol.　2009/06　Research paper (scientific journal)

Another story of arginines in voltage sensing: the role of phosphoinositides in coupling voltage sensing to enzyme activity

Yasushi Okamura

JOURNAL OF GENERAL PHYSIOLOGY　Vol. 134　No. 1　p. 1-4　2009/06　Research paper (scientific journal)

Voltage-gated proton channel is expressed on phagosome.

Yoshifumi Okochi, Mari Sasaki, Yasushi Okamura

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS　Vol. 382　No. 2　p. 274-279　2009/05　Research paper (scientific journal)

VSOP Protein Lacking the C-terminal Half of S4-like Segment Retains Proton Permeation

黒川竜紀, 高木正浩, 坂田宗平, 大河内善史, 岡村康司

Biophys. J. Supplement.　2009/03　Research paper (international conference proceedings)

Voltage Sensitive Phosphatase from Xenopus Laevis Testis.

William J. Ratzan, Yasushi Okamura, Laurinda A. Jaffe

Biophysical Journal, Volume 96, Issue 3, Supplement 1,　2009/02　Research paper (international conference proceedings)

Voltage-sensing phosphatase: actions and potentials

Yasushi Okamura, Yoshimichi Murata, Hirohide Iwasaki

JOURNAL OF PHYSIOLOGY-LONDON　Vol. 587　No. 3　p. 513-520　2009/02

Ion Channel Clustering at the Axon Initial Segment and Node of Ranvier Evolved Sequentially in Early Chordates

Alexis S. Hill, Atsuo Nishino, Koichi Nakajo, Giuxin Zhang, Jaime R. Fineman, Michael E. Selzer, Yasushi Okamura, Edward C. Cooper

PLOS GENETICS　Vol. 4　No. 12　2008/12　Research paper (scientific journal)

高膜電位におけるCi-VSPの電位依存的なホスファターゼ活性の解析.

坂田宗平, Hossain MI, 岡村康司

Neurosci. Res. Supplement　2008/09　Research paper (international conference proceedings)

Improving membrane voltage measurements using FRET with new fluorescent proteins

Hidekazu Tsutsui, Satoshi Karasawa, Yasushi Okamura, Atsushi Miyawaki

NATURE METHODS　Vol. 5　No. 8　p. 683-685　2008/08　Research paper (scientific journal)

Functional analysis of synaptotagmin gene regulatory regions in two distantly related ascidian species

Jun Matsumoto, You Katsuyama, Yukio Ohtsuka, Patrick Lemaire, Yasushi Okamura

DEVELOPMENT GROWTH & DIFFERENTIATION　Vol. 50　No. 7　p. 543-552　2008/08　Research paper (scientific journal)

電位依存性プロトンチャネルVSOPのダイマー形成.

黒川竜紀, Hans Koch, 大河内善史, 佐々木真理, Peter Larsson, 岡村康司

Neurosci. Res. Supplement　2008/07　Research paper (international conference proceedings)

Multimeric nature of voltage-gated proton channels

Hans P. Koch, Tatsuki Kurokawa, Yoshifumi Okochi, Mari Sasaki, Yasushi Okamura, H. Peter Larsson

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA　Vol. 105　No. 26　p. 9111-9116　2008/07　Research paper (scientific journal)

Enzyme Domain Affects The Movement Of The Voltage Sensor In Ascidian And Zebrafish VSPs

Hossain MI, Iwasaki H, Okochi Y, Chahine M, Higashijima S, Nagayama K, Okamura Y

J Biol Chem　2008/06　Research paper (scientific journal)

Enzyme domain affects the movement of the voltage sensor in ascidian and zebrafish voltage-sensing phosphatases

Md. Israil Hossain, Hirohide Iwasaki, Yoshifumi Okochi, Mohamed Chahine, Shinichi Higashijima, Kuniaki Nagayama, Yasushi Okamura

JOURNAL OF BIOLOGICAL CHEMISTRY　Vol. 283　No. 26　p. 18248-18259　2008/06　Research paper (scientific journal)

A voltage-sensing phosphatase, Ci-VSP, which shares sequence identity with PTEN, dephosphorylates phosphatidylinositol 4,5-bisphosphate

Hirohide Iwasaki, Yoshimichi Murata, Youngjun Kim, Md. Israil Hossain, Carolyn A. Worby, Jack E. Dixon, Thomas McCormack, Takehiko Sasaki, Yasushi Okamura

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA　Vol. 105　No. 23　p. 7970-7975　2008/06　Research paper (scientific journal)

Detailed comparison of expressed and native voltage-gated proton channel currents

B. Musset, V. V. Cherny, D. Morgan, Y. Okamura, I. S. Ramsey, D. E. Clapham, T. E. Decoursey

Journal of Physiology　Vol. 586　No. 10　p. 2477-2486　2008/05/15　Research paper (scientific journal)

Voltage range of voltage-dependent tuning of phosphatase activity of Ci-VSP.

Yasushi Okamura, Md. Hossain, Yoshimichi Murata, Yoshihiko Kubo

2008/03　Research paper (international conference proceedings)

電位依存性プロトンチャネルの分子構成.

黒川竜紀, 大河内善史, 佐々木真理, 高木正浩, 岡村康司

J. Physiol. Sci. supplement.　2008/03　Research paper (international conference proceedings)

Voltage-gated proton channels. In Symposium "Voltage-dependent Proton Channels Come of Age

Okamura, Y

2008/02　Research paper (international conference proceedings)

Voltage range for tuning of phosphatase of Ci-VSP as measured by two PIP2-sensors.

Hossain, M.I, Sakata, S, Murata, Y, Okamura, Y

Biophysical Journal Volume 94, Issue 2, Supplement 1, February 2008,　2008/02　Research paper (international conference proceedings)

貪食細胞における電位依存性プロトンチャネルVSOPの機能解析.

大河内善史, 佐々木真理, 黒川竜紀, 岩崎広英, 岡村康司

2007/12　Research paper (international conference proceedings)

電位依存性プロトンチャネルのオリゴマー形成.

黒川竜紀, 大河内善史, 佐々木真理, 岩崎広英, 岡村康司

2007/12　Research paper (international conference proceedings)

Analysis of a voltage-gated proton channel, VSOP in microglia

大河内善史, 澤田 誠, 佐々木真理, 岩崎広英, 岡村康司

2007/09

Cloning and characterization of an ascidian AMPA receptor

Shinobu Hirai, Atsuo Nishino, Hiroki Takahashi, Yasushi Okamura, Haruo Okado

NEUROSCIENCE RESEARCH　Vol. 58　p. S193-S193　2007/09　Research paper (international conference proceedings)

Depolarization activates the phosphoinositide phosphatase GNP, as detected in Xenopus oocytes coexpressing sensors of PIP2

Yoshimichi Murata, Yasushi Okamura

JOURNAL OF PHYSIOLOGY-LONDON　Vol. 583　No. 3　p. 875-889　2007/07　Research paper (scientific journal)

Phagocytosis and membrane potential

OKAMURA Yasushi, SASAKI Mari

Vol. 79　No. 5　p. 454-458　2007/05　Research paper (scientific journal)

Phagocytosis and membrane potential

Yasushi Okamura, Mari Sasaki

SEIKAGAKU　Vol. 79　No. 5　p. 454-458　2007/05

電位依存性プロトンチャネルの分子相関比 ( stoichiometry) の解析

黒川 竜紀, 岡村 康司

2007/03　Research paper (international conference proceedings)

電位依存性プロトンチャネル分子の分布パターンと生理機能.

岡村 康司, 大河内 善史, 佐々木 真理, 黒川 竜紀, 岩崎 広英

2007/03　Research paper (international conference proceedings)

電位依存性ホスファターゼの動作原理と役割

岡村 康司, 村田 喜理, ホッサイン イスレイル, 岩崎 広英, 佐々木 真理, 蒲野 淑子, 黒川 竜紀, 大河内 善史

2007/03　Research paper (international conference proceedings)

電位依存性ホスファターゼCi-VSPにおける、膜電位感知?酵素活性相関の機構

村田 喜理, 岡村 康司

2007/03　Research paper (international conference proceedings)

Phosphatase domain (PD) of voltage sensor containing phosphatase (VSP) modifies voltage sensor movement.

Hossain Md. Israil, Kuniaki Nagayama, Yasushi Okamura

2007/03　Research paper (international conference proceedings)

細胞膜電位センサー--電位依存性イオンチャンネルの新展開 (特集 細胞感覚とセルセンサー)

岡村康司

バイオニクス　Vol. 4　No. 1　p. 36-43　2007/01　Research paper (scientific journal)

Voltage-dependent calcium influx mediates maturation of myofibril arrangement in ascidian larval muscle

Yukio Ohtsuka, Yasushi Okamura

DEVELOPMENTAL BIOLOGY　Vol. 301　No. 2　p. 361-373　2007/01　Research paper (scientific journal)

Biodiversity of voltage sensor domain proteins

Yasushi Okamura

PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY　Vol. 454　No. 3　p. 361-371　2007/01　Research paper (scientific journal)

Composition of nicotinic acetylcholine receptor subunits at neuromuscular junctions of the ascidian Ciona intestinalis larva

Atsuo Nishino, Yasushi Okamura

ZOOLOGICAL SCIENCE　Vol. 23　No. 12　p. 1206-1206　2006/12

Ankyrin-G regulates inactivation gating of the neuronal sodium channel, Nav1.6

Emi Shirahata, Hirohide Iwasaki, Masahiro Takagi, Changqing Lin, Vann Bennett, Yasushi Okamura, Kiyoshi Hayasaka

JOURNAL OF NEUROPHYSIOLOGY　Vol. 96　No. 3　p. 1347-1357　2006/06　Research paper (scientific journal)

alx, a zebrafish homolog of Chx10, marks ipsilateral descending excitatory interneurons that participate in the regulation of spinal locomotor circuits

Y Kimura, Y Okamura, SI Higashijima

JOURNAL OF NEUROSCIENCE　Vol. 26　No. 21　p. 5684-5697　2006/05　Research paper (scientific journal)

A voltage sensor-domain protein is a voltage-gated proton channel

M Sasaki, M Takagi, Y Okamura

SCIENCE　Vol. 312　No. 5773　p. 589-592　2006/04　Research paper (scientific journal)

Role of cytoplasmic domain in voltage sensor movement of Zebrafish-VSP

Israil Hossain, Mari Sasaki, Yasushi Okamura

2006/03　Research paper (international conference proceedings)

電位センサードメインに存在する負電荷残基の、膜電位感受性酵素Ci-VSPの膜電位感受における役割

村田喜理, 岡村康司

2006/03　Research paper (international conference proceedings)

電位センサーの動作原理と電位感受性酵素VSP (特集 イオンチャネル・受容体の構造機能連関研究の新たな潮流)

岡村康司

細胞工学　Vol. 25　No. 3　p. 231-235　2006/03

Voltage sensor domain drives modification of phosphatase activity of the voltage sensor containing phosphatase, Ci-VSP.

Y. Murata, Y. Okamura

2006/02　Research paper (international conference proceedings)

膜電位を感じて活性を変化させるイノシトールリン脂質脱リン酸化酵素

岡村康司, 村田喜理, 岩崎広英

蛋白質核酸酵素　Vol. 51　No. 1　p. 18-26　2006/01　Research paper (scientific journal)

[New role of voltage sensor: voltage-regulated phosphatase recently identified from ascidian genome]

Okamura Y, Murata Y, Iwasaki H, Sasaki M

Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme　Vol. 51　p. 18-26　2006/01

Neuromuscular junctions and patterns of electrical excitations in tail muscle bands of the Ascidian Ciona intestinalis larva

Atsuo Nishino, Yasushi Okamura

ZOOLOGICAL SCIENCE　Vol. 22　No. 12　p. 1491-1491　2005/12

Phosphoinositide phosphatase activity coupled to an intrinsic voltage sensor

Hirohide Iwasaki, Yoshimichi Murata, Mari Sasaki, Kazuo Inaba, Yasushi Okamura

ZOOLOGICAL SCIENCE　Vol. 22　No. 12　p. 1449-1449　2005/12　Research paper (scientific journal)

GABAergic synaptic transmission modulates swimming in the ascidian larva

ER Brown, A Nishino, Q Bone, IA Meinertzhagen, Y Okamura

EUROPEAN JOURNAL OF NEUROSCIENCE　Vol. 22　No. 10　p. 2541-2548　2005/11　Research paper (scientific journal)

Comprehensive analysis of the ascidian genome reveals novel insights into the molecular evolution of ion channel genes

Yasushi Okamura, Atsuo Nishino, Yoshimichi Murata, Koichi Nakajo, Hirohide Iwasaki, Yukio Ohtsuka, Motoko Tanaka-Kunishima, Nobuyuki Takahashi, Yuji Hara, Takashi Yoshida, Motohiro Nishida, Haruo Okado, Hirofumi Watari, Ian A. Meinertzhagen, Nori Satoh, Kunitaro Takahashi, Yutaka Satou, Yasunobu Okada, Yasuo Mori

Physiological Genomics　Vol. 22　p. 269-282　2005/10　Research paper (scientific journal)

Regulation of Na-v channels in sensory neurons

M Chahine, R Ziane, K Vijayaragavan, Y Okamura

TRENDS IN PHARMACOLOGICAL SCIENCES　Vol. 26　No. 10　p. 496-502　2005/10　Research paper (scientific journal)

膜電位感受性酵素 Ci-VSPにおける、酵素活性の膜電位による制御機構ドメイン間リンカー領域の役割.

村田喜理, 佐々木真理, 岡村康司

2005/09　Research paper (international conference proceedings)

生命情報学によるゲノム進化の解析，

藤山秋佐夫, 三谷啓志, 岡村康司, 隅山健太

2005/09

新規電位センサー蛋白から見た脊索動物の生理機能の進化.

岡村康司, 岩崎広英, 佐々木真理, 村田喜理, Israil Hossain, 東島眞一

2005/09　Research paper (international conference proceedings)

Comprehensive analysis of the ascidian genome reveals novel insights into the molecular evolution of ion channel genes

Y Okamura, A Nishino, Y Murata, K Nakajo, H Iwasaki, Y Ohtsuka, M Tanaka-Kunishima, N Takahashi, Y Hara, T Yoshida, M Nishida, H Okado, H Watari, IA Meinertzhagen, N Satoh, K Takahashi, Y Satou, Y Okada, Y Mori

PHYSIOLOGICAL GENOMICS　Vol. 22　No. 3　p. 269-282　2005/08　Research paper (scientific journal)

胎生期マウス脊髄におけるGABAの興奮性作用へのK+-Cl-cotransporter強発現の効果，

中山希世美, 岡村康司

2005/07　Research paper (international conference proceedings)

電位センサータンパク質VSOP2の解析，

岩崎広英, 東島眞一, 岡村康司

2005/07　Research paper (international conference proceedings)

新しい膜電依存性タンパクの構造と機能，シンポジウム「バイオ分子センサー脳神経機能研究の新潮流」

岡村康司

2005/07　Research paper (international conference proceedings)

Phosphoinositide phosphatase activity coupled to an intrinsic voltage sensor

Y Murata, H Iwasaki, M Sasaki, K Inaba, Y Okamura

NATURE　Vol. 435　No. 7046　p. 1239-1243　2005/07　Research paper (scientific journal)

Tight junctions in Schwann cells of peripheral myelinated axons

Tatsuo Miyamoto, Kazumasa Morita, Daisuke Takemoto, Kosei Takeuchi, Yuka Kitano, Tsuyoshi Miyakawa, Kiyomi Nakayama, Yasushi Okamura, Hiroyuki Sasaki, Yoshiki Miyachi, Mikio Furuse, Shoichiro Tsukita

CELL STRUCTURE AND FUNCTION　Vol. 30　No. Supplement　p. 88-88　2005/06

カタユウレイボヤのイオンチャネル遺伝子データベースの作成

岡村康司, 西野敦雄, 小笠原道夫, 佐藤矩行, 岡戸晴生

2005/05　Research paper (international conference proceedings)

Identification of teleost voltage-sensitive phosphatase (VSP) and its comparison with Ci-VSP，

Israil Hossain, 東島眞一, 岩崎広英, 永山国昭, 岡村康司

2005/05　Research paper (international conference proceedings)

ホヤ幼生の遊泳運動機構の研究運動パターンと筋細胞の興奮・収縮の関係，

西野敦雄, 東島眞一, 岡村康司

2005/05　Research paper (international conference proceedings)

Roles of S4-enzyme linker for the coupling of voltage-sensing and phosphatase activity of the voltage-sensing phosphatase, Ci-VSP.

村田喜理, 岡村康司

2005/05　Research paper (international conference proceedings)

第82回日本生理学会シンポジウム「電位センサーをもつ酵素」

岡村康司

2005/05

Nav1.6チャネルの持続性Na電流の制御機構 (特集・Naチャネル)

白幡恵美, 早坂清, 岡村康司

生体の科学　Vol. 56　No. 3　p. 216-220　2005/05　Research paper (scientific journal)

Tight junctions in Schwann cells of peripheral myelinated axons: a lesson from claudin-19-deficient mice

T Miyamoto, K Morita, D Takemoto, K Takeuchi, Y Kitano, T Miyakawa, K Nakayama, Y Okamura, H Sasaki, Y Miyachi, M Furuse, S Tsukita

JOURNAL OF CELL BIOLOGY　Vol. 169　No. 3　p. 527-538　2005/05　Research paper (scientific journal)

Early specification of ascidian larval motor neurons

Y Katsuyama, T Okada, J Matsumoto, Y Ohtsuka, T Terashima, Y Okamura

DEVELOPMENTAL BIOLOGY　Vol. 278　No. 2　p. 310-322　2005/02　Research paper (scientific journal)

イオンチャネル遺伝子から見た生理機能の進化 (総特集 境界動物の生物学--脊椎動物への進化の研究最前線) -- (1章 ホヤ--世界に先駆ける先端研究)

岡村康司

海洋, 号外　No. 41　p. 61-70　2005　Research paper (scientific journal)

Locomotion patterns and electrical activities of tail muscle bands in the ascidian Ciona intestinalis larvae

Atsuo Nishino, Yasushi Okamura

ZOOLOGICAL SCIENCE　Vol. 21　No. 12　p. 1325-1325　2004/12

Development of transient outward currents coupled with Ca2+-induced Ca2+ release mediates oscillatory membrane potential in ascidian muscle cells

K Nakajo, Y Okamura

JOURNAL OF NEUROPHYSIOLOGY　Vol. 92　No. 2　p. 1056-1066　2004/08　Research paper (scientific journal)

The neurobiology of the Ascidian tadpole larva: Recent developments in an ancient chordate

IA Meinertzhagen, P Lemaire, Y Okamura

ANNUAL REVIEW OF NEUROSCIENCE　Vol. 27　p. 453-485　2004/07　Research paper (scientific journal)

Ci-VSPの膜電位感受性とホスファターゼ活性の相関，

村田喜理, 佐々木真理, 岩崎広英, 岡村康司

2004/06　Research paper (international conference proceedings)

新規膜電位感受性タンパク質；Ci-VSPにおけるゲート電流の解析，

佐々木真理, 岩崎広英, 村田喜理, 久木田文夫, 岡村康司

2004/06　Research paper (international conference proceedings)

膜電位感受性酵素Ci-VSPの酵素活性，

岩崎広英, 佐々木真理, 村田喜理, 岡村康司

2004/06　Research paper (international conference proceedings)

アンキリンGは発現系において電位依存性ナトリウムチャネルNav1.6の持続性電流を抑制する，

白幡恵美, 林長青, 岩崎広英, 早坂清, 岡村康司

2004/06　Research paper (international conference proceedings)

ホヤゲノムから見つかった新規膜電位センサー分子

岡村康司, 佐々木真理, 岩崎広英, 村田喜理

2004/06

The ascidian dihydropyridine-resistant calcium channel as the prototype of chordate L-type calcium channel

Y Okamura, H Izumi-Nakaseko, K Nakajo, Y Ohtsuka, T Ebihara

NEUROSIGNALS　Vol. 12　No. 3　p. 142-158　2003/08　Research paper (scientific journal)

DHP-insensitive L-type-like Ca channel of ascidian acquires sensitivity to DHP with single amino acid change in domain IIIP-region

H Izumi-Nakaseko, S Yamaguchi, Y Ohtsuka, T Ebihara, S Adachi-Akahane, Y Okamura

FEBS LETTERS　Vol. 549　No. 1-3　p. 67-71　2003/08　Research paper (scientific journal)

The functional characterization of cloned human sodium channel, Nav1.6 and evidence for unstable persistent current，

白幡恵美, 中瀬古ー泉寛子, 林長青, 早坂清, 岡村康司

2003/07　Research paper (international conference proceedings)

ホヤ幼生とイオンチャネル : 脊椎動物のミニチュア

岡村康司

バイオサイエンスとインダストリー = Bioscience & industry　Vol. 61　p. 44-45　2003/04　Research paper (scientific journal)

バクテリアの電位依存性イオンチャネル，NaChBacのイオン選択性およびpH依存性の解析，

村田喜理, 渡里博史, 三尾和弘, 佐藤主税, 高見英人, 岡村康司

2003/03　Research paper (international conference proceedings)

電位依存性ナトリウムチャネルNav1.6の新規スプライスバリアント，

岩崎広英, 泉ー中瀬古寛子, 岡村康司

2003/03　Research paper (international conference proceedings)

Primary structure, functional characterization and developmental expression of the ascidian Kv4-class potassium channel

K Nakajo, Y Katsuyama, F Ono, Y Ohtsuka, Y Okamura

NEUROSCIENCE RESEARCH　Vol. 45　No. 1　p. 59-70　2003/01　Research paper (scientific journal)

Coexpression of a Ca(v)1.2 protein lacking an N-terminus and the first domain specifically suppresses L-type calcium channel activity

T Ebihara, Y Komiya, H Izumi-Nakaseko, S Adachi-Akahane, S Okabe, Y Okamura

FEBS LETTERS　Vol. 529　No. 2-3　p. 203-207　2002/10　Research paper (scientific journal)

ホヤ初期胚における電位依存性カルシウムチャネルβサブユニットの発現様式

大塚幸雄, 岡村康司

2002/07　Research paper (international conference proceedings)

Ca2+放出で活性化されるCa2+依存性K+ チャネルの発現がホヤ筋細胞の膜興奮性のモードを切り替える

中條浩一, 岡村康司

2002/07　Research paper (international conference proceedings)

電位依存性NaチャネルNaV1.6の新規エクソンによるスプライシングバリアント

岡村康司

2002/07

Na〔+〕チャネル 電位依存性Na〔+〕チャネル--分子と機能の多様性に関する知見 (〔2002年〕6月第5土曜特集 イオンチャネルの最前線) -- (細胞膜イオンチャネル)

岡村康司

医学のあゆみ　Vol. 201　No. 13　p. 971-976　2002/06　Research paper (scientific journal)

The development of three identified motor neurons in the larva of an ascidian, Halocynthia roretzi

T Okada, Y Katsuyama, F Ono, Y Okamura

DEVELOPMENTAL BIOLOGY　Vol. 244　No. 2　p. 278-292　2002/04　Research paper (scientific journal)

Regulation of synaptotagmin gene expression during ascidian embryogenesis

Y Katsuyama, J Matsumoto, T Okada, Y Ohtsuka, L Chen, H Okado, Y Okamura

DEVELOPMENTAL BIOLOGY　Vol. 244　No. 2　p. 293-304　2002/04　Research paper (scientific journal)

電位依存性Naチャネルの機能、発現の制御

岡村康司, 泉寛子, 岡田俊明

2002/03　Research paper (international conference proceedings)

DHP非感受性のホヤL型Caチャネルが膜貫通ドメイン3のポア部分の1アミノ酸置換によりDHP感受性を獲得する，第79回日本生理学会大会 広島 平成14年3月 Japanese J. Physiol., suppl.

泉寛子, 山口真司, 赤羽悟美, 大塚幸雄, 岡村康司

2002/03

The DHP-insensitive L-type-like Ca2+ channel of ascidian acquires the DHP-sensitivity by a single-site substitution in the domain III P-region.

Nakaseko-Izumi, H, Yamaguchi, S, Ohtsuka, Y, Adachi-akahane, S, Okamura,Y

2002/01　Research paper (international conference proceedings)

Induction of ascidian peripheral neuron by vegetal blastomeres

Y Ohtsuka, T Obinata, Y Okamura

DEVELOPMENTAL BIOLOGY　Vol. 239　No. 1　p. 107-117　2001/11　Research paper (scientific journal)

Induction of ascidian peripheral neurons by vegetal blastomeres.

Ohtsuka Y, Obinata T, Okamura Y

Dev. Biol.　2001/11　Research paper (scientific journal)

The larval ascidian nervous system: the chordate brain from its small beginnings

LA Meinertzhagen, Y Okamura

TRENDS IN NEUROSCIENCES　Vol. 24　No. 7　p. 401-410　2001/07　Research paper (scientific journal)

Neuronal form in the central nervous system of the tadpole larva of the ascidian Ciona intestinalis

T Okada, SS MacIsaac, Y Katsuyama, Y Okamura, IA Meinertzhagen

BIOLOGICAL BULLETIN　Vol. 200　No. 3　p. 252-256　2001/06　Research paper (scientific journal)

Changes in gelsolin expression during ascidian metamorphosis

Y Ohtsuka, Y Okamura, T Obinata

DEVELOPMENT GENES AND EVOLUTION　Vol. 211　No. 5　p. 252-256　2001/05　Research paper (scientific journal)

Ca2+チャネルアゴ二ストはL型Ca2+チャネルa1CサブユニットIIIS5-S6ポア領域との相互作用を介してゲーティングを修飾する，

赤羽悟美, 山口真司, 長尾拓, 岡村康司

2001/03　Research paper (international conference proceedings)

ホヤ胚筋細胞におけるCa2+放出機構とCa2+活性化K+チャネルの発達，

中條浩一, 岡村康司

2001/03　Research paper (international conference proceedings)

SCN8a型Naチャネルの不活性化の機構

岡村康司

2001/03　Research paper (international conference proceedings)

Na+チャネル機能の多様性とその分子的基盤

岡村康司

2001/03　Research paper (international conference proceedings)

SCN8a型Na+チャネルの機能

岡村康司, 高安幸弘, 飯野昌枝, 小澤瀞司

2001/03　Research paper (international conference proceedings)

Serine residue in IIIS5-S6 linker of L-type Ca2+ channel alpha1C subunit plays a critical role in the action of DHP agonists.

Adachi-Akahane, Yamaguchi, S, Okamura,Y, Nagao,T

2001/02

The maternal transcript for truncated voltage-dependent Ca2+ channels in the ascidian embryo: A potential suppressive role in Ca2+ channel expression

R Okagaki, H Izumi, T Okada, H Nagahora, K Nakajo, Y Okamura

DEVELOPMENTAL BIOLOGY　Vol. 230　No. 2　p. 258-277　2001/02　Research paper (scientific journal)

Primary structure, developmental expression and functional properties of an inward rectifier K+ channel of the tunicate

Y Murata, H Okado, Y Katsuyama, Y Okamura, Y Kubo

RECEPTORS & CHANNELS　Vol. 7　No. 5　p. 387-399　2001/02　Research paper (scientific journal)

Novel determinant of action of DHP agonist in voltage-dependent L-type Ca2+ channel alpha(1C) subunit

S Yamaguchi, Y Okamura, T Nagao, S Adachi-Akahane

CALCIUM SIGNALI NG　Vol. 331　p. 124-126　2001　Research paper (international conference proceedings)

Multiple cis-regulatory regions control neuronal gene expression of synaptotagmin in ascidian embryos

J Matsumoto, Y Katsuyama, Y Okamura

BIOLOGY OF ASCIDIANS　p. 158-161　2001　Research paper (international conference proceedings)

Serine residue in the IIIS5-S6 linker of the L-type Ca2+ channel α1C subunit is the critical determinant of the action of dihydropyridine Ca2+ channel agonists

Shinji Yamaguchi, Yasushi Okamura, Taku Nagao, Satomi Adachi-Akahane

Journal of Biological Chemistry　Vol. 275　No. 52　p. 41504-41511　2000/12/29　Research paper (scientific journal)

Novel determinant of action of dihydropyridine agonists in voltage-dependent L-type Ca2+ channel alpha(1c) subunit

Nagao T, Yamaguchi S, Okamura Y

2000/10　Research paper (international conference proceedings)

電位依存性CaチャネルβサブユニットのC末端側の役割

大塚幸雄, 岡村康司

2000/09　Research paper (international conference proceedings)

発生過程での不完全長型サブユニットによる電位依存性Caチャネル電流発現の抑制

泉 寛子, 海老原 達彦, 岡村康司

2000/09　Research paper (international conference proceedings)

Diversity of voltage-gated sodium channels in the ascidian larval nervous system

H Nagahora, T Okada, N Yahagi, JA Chong, G Mandel, Y Okamura

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS　Vol. 275　No. 2　p. 558-564　2000/08　Research paper (scientific journal)

電位依存性カルシウムチャネルβサブユニットC末端領域の役割

大塚幸雄, 岡村康司

2000/03　Research paper (international conference proceedings)

truncated型alpha1サブユニットの共発現による電位依存性Caチャネルの発現量の調節

岡村康司

2000/03　Research paper (international conference proceedings)

ホヤ胚筋細胞Ca放出の細胞内Ca2+濃度による調節

中條浩一, 岡村康司

2000/03　Research paper (international conference proceedings)

Single Ca2+ channel activity and Ca2+ release in ascidian muscle.

Nakajo K, Okamura Y

2000/01　Research paper (international conference proceedings)

Subfamily-specific posttranscriptional regulation underlies K+ channel expression in a developing neuronal blastomere.

Ono F, Katsuyama Y, Nakajo K, Okamura Y

J. Neurosci.　1999/09　Research paper (scientific journal)

Subfamily-specific posttranscriptional mechanism underlies K+ channel expression in a developing neuronal blastomere

F Ono, Y Katsuyama, K Nakajo, Y Okamura

JOURNAL OF NEUROSCIENCE　Vol. 19　No. 16　p. 6874-6886　1999/08　Research paper (scientific journal)

ホヤ発生過程におけるシナプトタグミン遺伝子の転写調節

勝山裕, 岡村康司

1999/07　Research paper (international conference proceedings)

ホヤ胚膜電位依存性Ca2+チャネルの神経及び筋細胞に共通する発現

中條浩一, 岡村康司, 岡田俊昭, 岡垣竜吾, 陳玲

1999/07　Research paper (international conference proceedings)

蛍光測光によるホヤ胚筋分化過程での細胞内Ca2＋ストアの発達の解析

中條浩一, 岡村康司

1999/03　Research paper (international conference proceedings)

ホヤ電位依存性カルシウムイオンチャネルβサブユニットの役割

大塚幸雄, 岡村康司

1999/03　Research paper (international conference proceedings)

マボヤ神経誘導割球に発現するKv2チャネル遺伝子の転写後調節

小野富三人, 中條浩一, 岡村康司

1999/03　Research paper (international conference proceedings)

マボヤ内向き整流性K＋チャネルの電気生理学的性質と、その発現部位

村田喜理, 岡戸晴生, 岡村康司, 久保義弘

1999/03　Research paper (international conference proceedings)

原索動物Ｌ型Ca2＋チャネルcDNAの機能的解析

岡村康司

1999/03　Research paper (international conference proceedings)

Cross-coupling between voltage-dependent Ca2+ channels and ryanodine receptors in developing ascidian muscle blastomeres

K Nakajo, L Chen, Y Okamura

JOURNAL OF PHYSIOLOGY-LONDON　Vol. 515　No. 3　p. 695-710　1999/03　Research paper (scientific journal)

ADSL system for time periodic noise environments

Y Okamura, H Okado, T Koyama

NEC RESEARCH & DEVELOPMENT　Vol. 40　No. 1　p. 64-69　1999/01　Research paper (scientific journal)

Functional expression of a protochordate L-type Ca2+ channel

Okamura Y

1999/01　Research paper (international conference proceedings)

ホヤ幼生とイオンチャネル脊椎動物のミニチュア

岡村康司

バイオサイエンスとインダストリー = Bioscience & industry　Vol. 57　No. 1　p. 9-10　1999/01/01

Basic fibroblast growth factor induction of neuronal ion channel expression in ascidian ectodermal blastomeres

T Inazawa, Y Okamura, K Takahashi

JOURNAL OF PHYSIOLOGY-LONDON　Vol. 511　No. 2　p. 347-359　1998/09　Research paper (scientific journal)

Na+チャネルの構造と機能 (特集 イオンチャネルとレセプタ---生理と病態)

岡村康司

神経研究の進歩　Vol. 42　No. 2　p. 192-201　1998/04　Research paper (scientific journal)

Ion channels and early development of neural cells

K Takahashi, Y Okamura

PHYSIOLOGICAL REVIEWS　Vol. 78　No. 2　p. 307-337　1998/04　Research paper (scientific journal)

Distinct neuronal lineages of the ascidian embryo revealed by expression of a sodium channel gene

Toshiaki Okada, Hiroshi Hirano, Kunitaro Takahashi, Yasushi Okamura

Developmental Biology　Vol. 190　No. 2　p. 257-272　1997/10/15　Research paper (scientific journal)

Na+チャネル (脳における情報伝達--神経機能素子と素過程) -- (興奮の伝導と伝達 イオンチャネルとイオンポンプ)

岡村康司

蛋白質核酸酵素　Vol. 42　No. 3　p. 208-212　1997/02　Research paper (scientific journal)

Neuronal differentiation and Na^+ channel expression in the two-interacting ascidian blatomeres

TAKAHASHI Kunitaro, SAITOE Minoru, OKAMURA Yasushi

Seibutsu Butsuri　Vol. 36　No. 3　p. 134-138　1996/05　Research paper (scientific journal)

Distinct regulation of two ion channel genes at neural induction

Yahagi,N.Okamura, Y.Takahashi,K

1995/07　Research paper (international conference proceedings)

Neuron-specific gene expression of Na+channel in a single neurally-induced blastomere

Ono,F.Okamura,Y

1995/07　Research paper (international conference proceedings)

Expression of transcripts for a truncated calcium channel precedes transcription for a full-length protein in developing ascidians

Okagaki, R.Okamura,Y

1995/04　Research paper (international conference proceedings)

NEURONAL EXCITABILITY IS INDUCED BY CELL-CELL INTERACTIONS DURING EARLY EMBRYOGENESIS

K TAKAHASHI, Y OKAMURA

PERSPECTIVES ON DEVELOPMENTAL NEUROBIOLOGY　Vol. 2　No. 4　p. 317-325　1995/02　Research paper (scientific journal)

Molecular cloning of putative Ca2+ channel gene from ascidian embryos.

岡垣竜吾, 岡村康司

1994/12　Research paper (international conference proceedings)

A putative sodium channel gene specifically expressed in ascidian motoneuron lineage.

Okamura Y, Nagahora H, Okada T. TuNaII

1994/12　Research paper (international conference proceedings)

胚発生におけるカルシウムチャネル電流変化の分子機構

岡垣竜吾, 岡村康司

1994/12　Research paper (international conference proceedings)

Regulation of Ion Channel Gene Expression during Ascidian Embryogenesis Basic Neurosciences of Invertebrates.Tokyo

Okamura,Y.Ono, F.Okagaki,R

1994/11　Research paper (international conference proceedings)

NEURAL EXPRESSION OF A SODIUM-CHANNEL GENE REQUIRES CELL-SPECIFIC INTERACTIONS

Y OKAMURA, F ONO, R OKAGAKI, JA CHONG, G MANDEL

NEURON　Vol. 13　No. 4　p. 937-948　1994/10　Research paper (scientific journal)

ホヤ胚単離外胚葉性割球に対する3種の神経誘導法の比較解析

稲津健志, 岡村康司, 高橋國太郎

1994/04　Research paper (international conference proceedings)

ホヤ2細胞系での神経誘導におけるNa+チャネル遺伝子の発現

小野富三人, 岡村康司

1993/12　Research paper (international conference proceedings)

THE ASCIDIAN EMBRYO AS A PROTOTYPE OF VERTEBRATE NEUROGENESIS

Y OKAMURA, H OKADO, K TAKAHASHI

BIOESSAYS　Vol. 15　No. 11　p. 723-730　1993/11　Research paper (scientific journal)

NEURAL INDUCTION SUPPRESSES EARLY EXPRESSION OF THE INWARD-RECTIFIER K+ CHANNEL IN THE ASCIDIAN BLASTOMERE

Y OKAMURA, K TAKAHASHI

JOURNAL OF PHYSIOLOGY-LONDON　Vol. 463　p. 245-268　1993/04　Research paper (scientific journal)

原索動物Na+チャネルの一時構造

岡村康司, 岡垣竜吾, 小野富三人, Mandel,G

1993/04　Research paper (international conference proceedings)

Na+チャネルの分子生物学の進歩

岡村康司

日本臨床　Vol. 51　No. 4　p. p1092-1101　1993/04　Research paper (scientific journal)

原索動物ホヤのNaチャネルcDNAのクローニング

岡村康司, 重本尚

1992/04　Research paper (international conference proceedings)

Ion channel evolution

Brehm P, Okamura Y, Mandel G

Seminars in Neurosci.　1991/10　Research paper (scientific journal)

Regulation of neuron specific Na+channel expression in ascidian embryosOkazakiMarch 1995. Japanese Journal of Physiology Supplement

Ono,F.Okamura, Y.Takahashi,K

1991/02　Research paper (international conference proceedings)

Regulation of Sodium Channels in Developing Tunicates.

Okamura,Y, Chong, J.A. Mandel

1991/02　Research paper (international conference proceedings)

Sequential Appearance of Functionally Distinct Sodium Chanels in an Isolated,Neurally-differentiating Cell From the Ascidian Embryo.

Okamura,Y, Shidara,M

1990/04

Suppression of transcription of inward-rectifier K+ channel by neural induction in ascidian embryos.

Yasushi Okamura, Kunitaro Takahashi

1989/11　Research paper (international conference proceedings)

TEA-sensitive and TEA-resistant delayed rectifier K channels in the cleavage-arrested ascidian embryo.

Munetaka Shidara, Yasushi Okamura

1988/12　Research paper (scientific journal)

分裂を制御した予定神経及び予定脊索2割球系における誘導性神経分化第

岡戸晴生, 岡村康司, 高橋國太郎

Neuroscience Research Supplements, Volume 9, 1989, Page 74　1988/04　Research paper (scientific journal)

Developmental changes in Na+ channels during neural-type differentiation in the isolated and cleavage-arrested blastomere of the tunicate embryo.

Yasushi Okamura, Munetaka Shidara

1987/12　Research paper (scientific journal)

ホヤ胚神経型分化に伴うNaチャネルの卵細胞型から分化型への転換

設楽宗孝, 岡村康司

1987/04　Research paper (scientific journal)

単離培養した分裂停止ホヤ4細胞胚割球における神経分化とNaチャネル

岡村康司, 岡戸晴生, 高橋國太郎

1986/12　Research paper (scientific journal)

分裂停止ホヤ4細胞胚頭側割球の神経方分化に伴うNaチャネルの質的変化

岡村康司, 設楽宗孝

1986/12　Research paper (scientific journal)

MORPHOLOGY OF FREEZE-SUBSTITUTED MYELINATED AXON IN MOUSE PERIPHERAL-NERVES

Y OKAMURA, S TSUKITA

BRAIN RESEARCH　Vol. 383　No. 1-2　p. 146-158　1986/09　Research paper (scientific journal)

凍結置換された神経軸索の外形

岡村康司, 月田承一郎

1983/05