Osaka University Graduate School of Engineering Science Department of Materials Engineering Science Division of Chemical Engineering
2016/10 - 2019/03
Osaka University Graduate School of Engineering Science Department of Materials Engineering Science Division of Chemical Engineering
2015/04 - 2016/09
溶液化学研究会 編集委員 Academic society
2021/11 -
溶液化学研究会
日本膜学会
化学工学会
Nanotechnology/Materials / Nanobioscience /
Manufacturing technology (mechanical, electrical/electronic, chemical engineering) / Applied biofunctional and bioprocess engineering /
Life sciences / Biophysics / lipid membrane
大阪大学賞 若手教員部門
大阪大学 2023/11
豊田理研スカラー
公益財団法人豊田理化学研究所 2022/04
第38回井上研究奨励賞
公益財団法人井上科学振興財団 2021/12
Engineering Liposomes in Microfluidic Mixing: The Critical Role of Lipid Membrane Properties in Formation and Precise Size Control
Junghu Lee, Nozomi Morishita Watanabe, Noriko Yoshimoto, Seonghyeon Eom, Hosup Jung, Hiroshi Umakoshi
Langmuir 2025/08/08 Research paper (scientific journal)
Characterizing the embedded states of a fluorescent probe within a lipid bilayer using molecular dynamics simulations
Ryo Okabe, Natsuumi Ito, Yuya Matsubara, Nozomi Morishita Watanabe, Hiroshi Umakoshi, Kento Kasahara, Nobuyuki Matubayasi
The Journal of Chemical Physics 2025/07/21 Research paper (scientific journal)
Design of i-Motif DNA-Modified Liposomes: Membrane Modulation and Drug Release Control
Kazuhiro Watanabe, Nozomi Morishita Watanabe, Yukihiro Okamoto, Hiroshi Umakoshi
ACS Applied Bio Materials 2025/07/21 Research paper (scientific journal)
Effects of hydrophobic drug incorporation on cubosome–cell membrane model interactions
Ward Wakileh, Nozomi Morishita Watanabe, Yuki Amatsu, Hiroshi Umakoshi
Chemistry Letters 2025/07/08 Research paper (scientific journal)
Interactions of Cubosomes with Cell Membrane Lipids: Revealed through Cubic Membrane Property Analysis
Ward Wakileh, Nozomi Morishita Watanabe, Zachary Nicolella, Yuki Amatsu, Naoko Kajimura, Hiroshi Umakoshi
Langmuir 2025/05/06 Research paper (scientific journal)
Investigation of Cubosome Interactions with Liposomal Membranes Based on Time-Resolved Small-Angle X-ray Scattering and Laurdan Fluorescence Spectroscopy
Ward Wakileh, Nozomi Morishita Watanabe, Yuki Amatsu, Hiroshi Sekiguchi, Naoko Kajimura, Nanaki Kadonishi, Hiroshi Umakoshi
The Journal of Physical Chemistry B 2025/03/06 Research paper (scientific journal)
Interaction Analysis between Cationic Lipid and Oligonucleotide with a Lipid Membrane-Immobilized Monolith Silica Column: A High-Performance Liquid Chromatography Approach
Junghu Lee, Noriko Yoshimoto, Hayato Takase, Nozomi Morishita Watanabe, Yukihiro Okamoto, Hiroshi Umakoshi
Langmuir Vol. 41 No. 4 p. 2214-2223 2025/02/04 Research paper (scientific journal)
Multifocal lipid membrane characterization by combination of DAS-deconvolution and anisotropy
Natsuumi Ito, Nozomi Morishita Watanabe, Yukihiro Okamoto, Hiroshi Umakoshi
Biophysical Journal Vol. 123 No. 23 p. 4135-4146 2024/12/03 Research paper (scientific journal)
Investigating the impact of 2-OHOA-embedded liposomes on biophysical properties of cancer cell membranes via Laurdan two-photon microscopy imaging
Xuehui Rui, Yukihiro Okamoto, Shuichiro Fukushima, Nozomi Morishita Watanabe, Hiroshi Umakoshi
Scientific Reports Vol. 14 No. 1 2024/12 Research paper (scientific journal)
Exploring pH-Triggered Lamellar to Cubic Phase Transition in 2-Hydroxyoleic Acid/Monoolein Nanodispersions: Insights into Membrane Physicochemical Properties
Xuehui Rui, Nozomi Morishita Watanabe, Yukihiro Okamoto, Ward Wakileh, Hiroshi Umakoshi
Journal of Physical Chemistry B Vol. 128 No. 38 p. 9151-9162 2024/09/26 Research paper (scientific journal)
Preparation and characterization of macrophage membrane camouflaged cubosomes as a stabilized and immune evasive biomimetic nano-DDS.
Xuehui Rui, Yukihiro Okamoto, Nozomi Morishita Watanabe, Taro Shimizu, Ward Wakileh, Naoko Kajimura, Hiroshi Umakoshi
Journal of materials chemistry. B Vol. 12 No. 35 p. 8702-8715 2024/09/11 Research paper (scientific journal)
Enhanced Curcumin Delivery and Stability through Natural Deep Eutectic Solvent-Based Niosomes
Thaaranni Bashkeran, Azlina Harun, Hiroshi Umakoshi, Nozomi Watanabe, Masrina Mohd Nadzir
Journal of Molecular Liquids 2024/09 Research paper (scientific journal)
A methodology of quantifying membrane permeability based on returning probability theory and molecular dynamics simulation
Yuya Matsubara, Ryo Okabe, Ren Masayama, Nozomi Morishita Watanabe, Hiroshi Umakoshi, Kento Kasahara, Nobuyuki Matubayasi
The Journal of Chemical Physics Vol. 161 No. 2 2024/07/10 Research paper (scientific journal)
Publisher: AIP Publishing
Influence of cholesterol on hydrogen-bond dynamics of water molecules in lipid-bilayer systems at varying temperatures
Kokoro Shikata, Kento Kasahara, Nozomi Morishita Watanabe, Hiroshi Umakoshi, Kang Kim, Nobuyuki Matubayasi
The Journal of Chemical Physics Vol. 161 No. 1 2024/07/03 Research paper (scientific journal)
Publisher: AIP Publishing
Exploring the Influence of Morphology on Bipolaron–Polaron Ratios and Conductivity in Polypyrrole in the Presence of Surfactants
Thaneeya Samwang, Nozomi Morishita Watanabe, Yukihiro Okamoto, Hiroshi Umakoshi
Molecules Vol. 29 No. 6 2024/03 Research paper (scientific journal)
Preparation and Characterization of Biodegradable Sponge-like Cryogel Particles of Chitosan via the Inverse Leidenfrost (iLF) Effect
Endang Ciptawati, Hayato Takase, Nozomi Morishita Watanabe, Yukihiro Okamoto, Hadi Nur, Hiroshi Umakoshi
ACS Omega Vol. 9 No. 2 p. 2383-2390 2024/01/16 Research paper (scientific journal)
Significance of in situ quantitative membrane property–morphology relation (QmPMR) analysis
Zachary Nicolella, Yukihiro Okamoto, Nozomi Morishita Watanabe, Gary Lee Thompson, Hiroshi Umakoshi
Soft Matter 2024 Research paper (scientific journal)
Solvation dynamics on the diffusion timescale elucidated using energy-represented dynamics theory
Kazuya Okita, Natsuumi Ito, Nozomi Morishita Watanabe, Hiroshi Umakoshi, Kento Kasahara, Nobuyuki Matubayasi
Physical Chemistry Chemical Physics 2024 Research paper (scientific journal)
Study of Chemical Polymerization of Polypyrrole with SDS Soft Template: Physical, Chemical, and Electrical Properties
Thaneeya Samwang, Nozomi Morishita Watanabe, Yukihiro Okamoto, Sira Srinives, Hiroshi Umakoshi
ACS Omega Vol. 8 No. 51 p. 48946-48957 2023/12/26 Research paper (scientific journal)
Multiplicity of solvent environments in lipid bilayer revealed by DAS deconvolution of twin probes: Comparative method of Laurdan and Prodan
Natsuumi Ito, Nozomi Morishita Watanabe, Yukihiro Okamoto, Hiroshi Umakoshi
Biophysical Journal 2023/12 Research paper (scientific journal)
Niosomes in cancer treatment: A focus on curcumin encapsulation
Thaaranni Bashkeran, Azlina Harun Kamaruddin, Trung Xuan Ngo, Kazuma Suda, Hiroshi Umakoshi, Nozomi Watanabe, Masrina Mohd Nadzir
Heliyon 2023/08 Research paper (scientific journal)
Dispersibility and surface properties of hydrocortisone-incorporated self-assemblies
Ward Wakileh, Nozomi Watanabe, Keishi Suga, Naoki Ikushima, Naoko Kajimura, Kaoru Mitsuoka, Yukihiro Okamoto, Hiroshi Umakoshi
Colloids and Surfaces A: Physicochemical and Engineering Aspects Vol. 665 p. 131217-131217 2023/05 Research paper (scientific journal)
Publisher: Elsevier BV
Preparation of Hydrophobic Monolithic Supermacroporous Cryogel Particles for the Separation of Stabilized Oil-in-Water Emulsion
Hayato Takase, Nozomi Watanabe, Koichiro Shiomori, Yukihiro Okamoto, Endang Ciptawati, Hideki Matsune, Hiroshi Umakoshi
Colloids and Interfaces Vol. 7 No. 1 p. 9-9 2023/01/17 Research paper (scientific journal)
Publisher: MDPI AG
Versatility of the Preparation Method for Macroporous Cryogel Particles Utilizing the Inverse Leidenfrost Effect
Hayato Takase, Nozomi Watanabe, Koichiro Shiomori, Yukihiro Okamoto, Hideki Matsune, Hiroshi Umakoshi
ACS Omega Vol. 8 No. 1 p. 829-834 2022/12/19 Research paper (scientific journal)
Publisher: American Chemical Society (ACS)
Revealed Properties of Various Self-Assemblies in Two Catanionic Surfactant Systems in Relation to Their Polarity and Molecular Packing State
Nozomi Watanabe, Shuto Watase, Nanaki Kadonishi, Yukihiro Okamoto, Hiroshi Umakoshi
Langmuir 2022/12/06 Research paper (scientific journal)
Micro Sponge Balls: Preparation and Characterization of Sponge-like Cryogel Particles of Poly(2-hydroxyethyl methacrylate) via the Inverse Leidenfrost Effect
Hayato Takase, Koichiro Shiomori, Yukihiro Okamoto, Nozomi Watanabe, Hideki Matsune, Hiroshi Umakoshi
ACS Applied Polymer Materials Vol. 4 No. 10 p. 7081-7089 2022/09/06 Research paper (scientific journal)
Publisher: American Chemical Society (ACS)
Characterization of entrapment behavior of polyphenols in nanostructured lipid carriers and its effect on their antioxidative activity
Ni'matul Izza, Nozomi Watanabe, YUKIHIRO OKAMOTO, Yusuf Wibisono, Hiroshi Umakoshi
Journal of Bioscience and Bioengineering Vol. 134 No. 3 p. 269-275 2022/09 Research paper (scientific journal)
Publisher: Elsevier BV
Characterization of Phase Separated Planar Lipid Bilayer Membrane by Fluorescence Ratio Imaging and Scanning Probe Microscope
YUKIHIRO OKAMOTO, Kaito Hamaguchi, Mayo Watanabe, Nozomi Watanabe, Hiroshi Umakoshi
Membranes Vol. 12 No. 8 p. 770-770 2022/08/09 Research paper (scientific journal)
Publisher: MDPI AG
Dependence of the Core–Shell Structure on the Lipid Composition of Nanostructured Lipid Carriers: Implications for Drug Carrier Design
Ni’matul Izza, Nozomi Watanabe, Yukihiro Okamoto, Keishi Suga, Yusuf Wibisono, Naoko Kajimura, Kaoru Mitsuoka, Hiroshi Umakoshi
ACS Applied Nano Materials Vol. 5 No. 7 p. 9958-9969 2022/07/22 Research paper (scientific journal)
Publisher: American Chemical Society (ACS)
Insight into the Exosomal Membrane: From Viewpoints of Membrane Fluidity and Polarity
Keishi Suga, Daiki Matsui, Nozomi Watanabe, Yukihiro Okamoto, Hiroshi Umakoshi
Langmuir Vol. 37 No. 38 p. 11195-11202 2021/09/28 Research paper (scientific journal)
Publisher: American Chemical Society (ACS)
Modulation of the Belousov–Zhabotinsky Reaction with Lipid Bilayers: Effects of Lipid Head Groups and Membrane Properties
Michael S. Chern, Nozomi Watanabe, Keishi Suga, Yukihiro Okamoto, Hiroshi Umakoshi
Langmuir Vol. 37 No. 22 p. 6811-6818 2021/06/08 Research paper (scientific journal)
Publisher: American Chemical Society (ACS)
Systematic Characterization of Nanostructured Lipid Carriers from Cetyl Palmitate/Caprylic Triglyceride/Tween 80 Mixtures in an Aqueous Environment
Ni’matul Izza, Keishi Suga, Yukihiro Okamoto, Nozomi Watanabe, Tham Thi Bui, Yusuf Wibisono, Cut Rifda Fadila, Hiroshi Umakoshi
Langmuir Vol. 37 No. 14 p. 4284-4293 2021/04/13 Research paper (scientific journal)
Publisher: American Chemical Society (ACS)
Effects of Lipid Bilayers and Polarity of the Organic Substrate on the Belousov–Zhabotinsky Reaction
Michael S. Chern, Nozomi Watanabe, Yukihiro Okamoto, Hiroshi Umakoshi
MEMBRANE Vol. 46 No. 4 p. 233-240 2021 Research paper (scientific journal)
Publisher: The Membrane Society of Japan
Changes Caused by Liposomes to the Belousov–Zhabotinsky Reaction
Michael S. Chern, Yukihiro Okamoto, Keishi Suga, Nozomi Watanabe, Hiroshi Umakoshi
The Journal of Physical Chemistry B Vol. 124 No. 44 p. 9862-9869 2020/11/05 Research paper (scientific journal)
Publisher: American Chemical Society (ACS)
Solvatochromic Modeling of Laurdan for Multiple Polarity Analysis of Dihydrosphingomyelin Bilayer
Watanabe, N., Goto, Y., Suga, K., Nyholm, T.K.M., Slotte, J.P., Umakoshi, H.
Biophysical Journal Vol. 116 No. 5 p. 874-883 2019 Research paper (scientific journal)
Lipid-Surrounding Water Molecules Probed by Time-Resolved Emission Spectra of Laurdan
Watanabe, N., Suga, K., Slotte, J.P., Nyholm, T.K.M., Umakoshi, H.
Langmuir Vol. 35 No. 20 p. 6762-6770 2019 Research paper (scientific journal)
Comparison of Physicochemical Membrane Properties of Vesicles Modified with Guanidinium Derivatives
Watanabe, N., Suga, K., Umakoshi, H.
Journal of Physical Chemistry B Vol. 121 No. 39 p. 9213-9222 2017 Research paper (scientific journal)
Effect of Stearylguanidinium-Modified POPC Vesicles on the Melting Behavior of tRNA Molecules
Suga, K., Watanabe, N., Umakoshi, H.
Journal of Physical Chemistry B Vol. 120 No. 25 p. 5662-9 2016 Research paper (scientific journal)
2OHOAナノ粒子により誘起される細胞膜特性変化に関する研究
岡本行広, RUI Xuehui, 渡邊望美, 馬越大
膜シンポジウム(CD-ROM) Vol. 2024 2024
時間分解蛍光分光法を用いた脂質膜特性の新規評価手法の開発
伊藤夏海, 渡邉望美, 岡本行広, 馬越大
膜シンポジウム(CD-ROM) Vol. 2024 2024
Design of biocompatible catanionic vesicles.
小川広太郎, 渡邉望美, 岡本行広, 馬越大
膜シンポジウム(CD-ROM) Vol. 2024 2024
Characterization of Lipid Nanoparticles Revealed through the Membrane Analysis
Vol. 48 No. 4 p. 168-172 2023/05
Tracking and Evaluation of Giant Vesicles’ behavior under AC Electric Field.
吉岡信幸, 岡本行広, 岡本行広, 渡邉望美, 馬越大
日本膜学会年会講演要旨集(CD-ROM) Vol. 45th 2023
Analysis of Membrane Fusion Dynamics of Cubosomes Using SAXS and Fluorescence Spectroscopy.
天津祐樹, 渡邉望美, 岡本行広, 馬越大
日本膜学会年会講演要旨集(CD-ROM) Vol. 45th 2023
Synthesis of low dimensional lead halide perovskites single crystals composed of chiral molecules
福森智子, GUEMBEL Lukas, KLEMENT Philip, 渡邉望美, 鈴木修一, CHATTERJEE Sangam, 馬越大, 夛田博一
応用物理学会春季学術講演会講演予稿集(CD-ROM) Vol. 70th 2023
偏光ラマン分光法による脂質二重膜解析を目指したSERS測定法の開発
藤山裕斗, 渡邉望美, 岡本行広, 馬越大
化学工学会秋季大会研究発表講演要旨集(CD-ROM) Vol. 54th 2023
非標準構造を形成する核酸修飾による薬剤内封リポソームの機能化
渡邊和宏, 渡邉望美, 岡本行広, 馬越大
化学工学会秋季大会研究発表講演要旨集(CD-ROM) Vol. 54th 2023
カタニオニック界面活性剤系の自己組織化構造とその特性
渡邉望美, 門西虹樹, 岡本行広, 馬越大
化学工学会秋季大会研究発表講演要旨集(CD-ROM) Vol. 54th 2023
平面脂質膜のミクロおよびマクロスケール解析法に関する研究
岡本行広, 濱口海都, 渡邊真与, 渡邊望美, 馬越大
日本分析化学会年会講演要旨集(Web) Vol. 71st 2022
Investigation of Science of Self-Assembly in Lipid Molecules
Vol. 50 p. 39-43 2021
Functional hydration behavior: Interrelation between hydration and molecular properties at lipid membrane interfaces
Nozomi Watanabe, Keishi Suga, Hiroshi Umakoshi
Journal of Chemistry Vol. 2019 2019 Article, review, commentary, editorial, etc. (scientific journal)
自己組織化材料におけるナノ界面物性の解析手法の検討
材料化学システム工学討論会2024 2024/10/24
Global-TRES 法を用いた脂質膜特性の新規評価手法の開発
伊藤 夏海, 渡邉 望美, 岡本 行広, 馬越 大
第４５回溶液化学プレシンポジウム 2023/10/17
非標準構造を有するi-motif核酸と脂質膜の相互作用解析
化学工学会 第52回秋季大会 2021/09/22
脂質膜における動的な水和状態評価のための時間分解蛍光スペクトル解析の研究
日本膜学会 膜シンポジウム 2020 2020/11/12
Characterizing the embedded states of a fluorescent probe within a lipid bilayer using molecular dynamics simulations
Okabe Ryo, Ito Natsuumi, Matsubara Yuya, Morishita Watanabe Nozomi, Umakoshi Hiroshi, Kasahara Kento, Matubayasi Nobuyuki
The Journal of Chemical Physics Vol. 163 No. 3 2025/07/16
A methodology of quantifying membrane permeability based on returning probability theory and molecular dynamics simulation
Matsubara Yuya, Okabe Ryo, Masayama Ren, Morishita Watanabe Nozomi, Umakoshi Hiroshi, Kasahara Kento, Matubayasi Nobuyuki
Journal of Chemical Physics Vol. 161 No. 2 2024/07/14
Investigating the impact of 2-OHOA-embedded liposomes on biophysical properties of cancer cell membranes via Laurdan two-photon microscopy imaging
Rui Xuehui, Okamoto Yukihiro, Fukushima Shuichiro, Morishita Watanabe Nozomi, Umakoshi Hiroshi
Scientific Reports Vol. 14 No. 1 2024/07/09
Solvation dynamics on the diffusion timescale elucidated using energy-represented dynamics theory
Okita Kazuya, Ito Natsuumi, Morishita-Watanabe Nozomi, Umakoshi Hiroshi, Kasahara Kento, Matubayasi Nobuyuki
Physical Chemistry Chemical Physics Vol. 26 No. 16 p. 12852-12861 2024/04/16
Studies on Characterization of Interfacial Properties of Lipid Bilayer Membranes and Its Application to Their Surface Design for Cooperative Molecular Interaction
渡邉 望美
