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Kikuchi Akira

菊池 章

Graduate School of Medicine Division of Medicine, Professor

Education

  • - 1988, Kobe University
  • - 1988, Kobe University, Graduate School, Division of Medicine
  • - 1982, Kobe University, School of Medicine
  • - 1982, Kobe University, Faculty of Medicine

Research History

  • 2009/12 - Present, 国立大学法人大阪大学
  • 2002/04 - 2009/11, Hiroshima University
  • 1994/12 - 2002/03, Hiroshima University, Faculty of Medicine
  • 1992/07 - 1994/11, University of California, San Francisco
  • 1992/06 - 1994/11, Kobe University, School of Medicine
  • 1988/04 - 1992/05, Kobe University, School of Medicine

Research Areas

  • Life sciences, Tumor biology
  • Life sciences, Pathobiochemistry
  • Life sciences, Cell biology
  • Life sciences, Molecular biology
  • Life sciences, Medical biochemistry

Papers

  • XCL1 expression correlates with CD8-positive T cells infiltration and PD-L1 expression in squamous cell carcinoma arising from mature cystic teratoma of the ovary., Ryo Tamura,Kosuke Yoshihara,Hirofumi Nakaoka,Nozomi Yachida,Manako Yamaguchi,Kazuaki Suda,Tatsuya Ishiguro,Koji Nishino,Hiroshi Ichikawa,Keiichi Homma,Akira Kikuchi,Yutaka Ueda,Yuji Takei,Hiroyuki Fujiwara,Teiichi Motoyama,Shujiro Okuda,Toshifumi Wakai,Ituro Inoue,Takayuki Enomoto, Oncogene, 2020/03/02
  • ARL4C is associated with initiation and progression of lung adenocarcinoma and represents a therapeutic target., Kenji Kimura,Shinji Matsumoto,Takeshi Harada,Eiichi Morii,Izumi Nagatomo,Yasushi Shintani,Akira Kikuchi, Cancer science, Vol. 111, No. 3, p. 951-961, 2020/03
  • Mark1 regulates distal airspace expansion through type I pneumocyte flattening in lung development., Katsumi Fumoto,Hisako Takigawa-Imamura,Kenta Sumiyama,Shige H Yoshimura,Natsumi Maehara,Akira Kikuchi, Journal of cell science, Vol. 132, No. 24, 2019/12/13
  • Dynamic palmitoylation controls the microdomain localization of the DKK1 receptors CKAP4 and LRP6., Ryota Sada,Hirokazu Kimura,Yuko Fukata,Masaki Fukata,Hideki Yamamoto,Akira Kikuchi, Science signaling, Vol. 12, No. 608, 2019/11/19
  • DKK1受容体であるCKAP4とLRP6の動的パルミチン酸化は細胞膜マイクロドメイン局在を誘導しDKK1シグナルを制御する(Dynamic palmitoylation determines membrane microdomain localization of two DKK1 receptors CKAP4 and LRP6, and regulates DKK1 signaling), Vol. 92回, p. [3P-198], 2019/09
  • DKK1新規受容体CKAP4は膵臓癌由来のエクソソームのバイオマーカーとがん治療の分子標的になる(CKAP4, a DKK1 receptor, is a biomarker in exosomes derived from pancreatic cancer and a molecular target for therapy), 山本 英樹,木村 公一,菊池 章, 日本癌学会総会記事, 日本癌学会, Vol. 78回, p. P-2085, 2019/09
  • GREB1 induced by Wnt signaling promotes development of hepatoblastoma by suppressing TGFβ signaling., Shinji Matsumoto,Taku Yamamichi,Koei Shinzawa,Yuuya Kasahara,Satoshi Nojima,Takahiro Kodama,Satoshi Obika,Tetsuo Takehara,Eiichi Morii,Hiroomi Okuyama,Akira Kikuchi, Nature communications, Vol. 10, No. 1, p. 3882-3882, 2019/08/28
  • CKAP4 Regulates Cell Migration via the Interaction with and Recycling of Integrin., Yoshihito Osugi,Katsumi Fumoto,Akira Kikuchi, Molecular and cellular biology, Vol. 39, No. 16, 2019/08/15
  • Correction to: Future projection of cancer patients with cardiovascular disease in Japan by the year 2039: a pilot study., Okura Y,Takayama T,Ozaki K,Tanaka H,Kikuchi A,Saito T,Tanigawa T,Takii Y,Seki H,Takenouchi T,Chou T,Sato N,Tanabe N,Minamino T, International journal of clinical oncology, 2019/04
  • CKAP4, a DKK1 Receptor, Is a Biomarker in Exosomes Derived from Pancreatic Cancer and a Molecular Target for Therapy., Hirokazu Kimura,Hideki Yamamoto,Takeshi Harada,Katsumi Fumoto,Yoshihito Osugi,Ryota Sada,Natsumi Maehara,Hayato Hikita,Soichiro Mori,Hidetoshi Eguchi,Masahito Ikawa,Tetsuo Takehara,Akira Kikuchi, Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 25, No. 6, p. 1936-1947, 2019/03/15
  • Wnt/β-catenin signaling, which is activated in odontomas, reduces Sema3A expression to regulate odontogenic epithelial cell proliferation and tooth germ development., Shinsuke Fujii,Kengo Nagata,Shinji Matsumoto,Ken-Ichi Kohashi,Akira Kikuchi,Yoshinao Oda,Tamotsu Kiyoshima,Naohisa Wada, Scientific reports, Vol. 9, No. 1, p. 4257-4257, 2019/03/12
  • Future projection of cancer patients with cardiovascular disease in Japan by the year 2039: a pilot study., Okura Y,Takayama T,Ozaki K,Tanaka H,Kikuchi A,Saito T,Tanigawa T,Takii Y,Seki H,Takenouchi T,Chou T,Sato N,Tanabe N,Minamino T, International journal of clinical oncology, 2019/03
  • Chemically Modified Antisense Oligonucleotide Against ARL4C Inhibits Primary and Metastatic Liver Tumor Growth., Takeshi Harada,Shinji Matsumoto,Suguru Hirota,Hirokazu Kimura,Shinsuke Fujii,Yuuya Kasahara,Hidetoshi Gon,Toshihiko Yoshida,Tomoo Itoh,Naotsugu Haraguchi,Tsunekazu Mizushima,Takehiro Noda,Hidetoshi Eguchi,Satoshi Nojima,Eiichi Morii,Takumi Fukumoto,Satoshi Obika,Akira Kikuchi, Molecular cancer therapeutics, Vol. 18, No. 3, p. 602-612, 2019/03
  • [Canonical Wnt signaling pathway and current issues.], Fumoto K,Kikuchi A, Clinical calcium, Vol. 29, No. 3, p. 283-289, 2019
  • p63-Dependent Dickkopf3 Expression Promotes Esophageal Cancer Cell Proliferation via CKAP4., Chihiro Kajiwara,Katsumi Fumoto,Hirokazu Kimura,Satoshi Nojima,Keita Asano,Kazuki Odagiri,Makoto Yamasaki,Hayato Hikita,Tetsuo Takehara,Yuichiro Doki,Eiichi Morii,Akira Kikuchi, Cancer research, Vol. 78, No. 21, p. 6107-6120, 2018/11/01
  • Map7/7D1 and Dvl form a feedback loop that facilitates microtubule remodeling and Wnt5a signaling., Koji Kikuchi,Akira Nakamura,Masaki Arata,Dongbo Shi,Mami Nakagawa,Tsubasa Tanaka,Tadashi Uemura,Toshihiko Fujimori,Akira Kikuchi,Akiyoshi Uezu,Yasuhisa Sakamoto,Hiroyuki Nakanishi, EMBO reports, Vol. 19, No. 7, 2018/07
  • Activation of the Dickkopf1-CKAP4 pathway is associated with poor prognosis of esophageal cancer and anti-CKAP4 antibody may be a new therapeutic drug., Naoki Shinno,Hirokazu Kimura,Ryota Sada,Shuji Takiguchi,Masaki Mori,Katsumi Fumoto,Yuichiro Doki,Akira Kikuchi, Oncogene, Vol. 37, No. 26, p. 3471-3484, 2018/06
  • Wnt5a-induced cell migration is associated with the aggressiveness of estrogen receptor-positive breast cancer., Yoshie Kobayashi,Takayuki Kadoya,Ai Amioka,Hideaki Hanaki,Shinsuke Sasada,Norio Masumoto,Hideki Yamamoto,Koji Arihiro,Akira Kikuchi,Morihito Okada, Oncotarget, Vol. 9, No. 30, p. 20979-20992, 2018/04/20
  • The Dickkopf1-cytoskeleton-associated protein 4 axis creates a novel signalling pathway and may represent a molecular target for cancer therapy., Akira Kikuchi,Katsumi Fumoto,Hirokazu Kimura, British journal of pharmacology, WILEY, Vol. 174, No. 24, p. 4651-4665, 2017/12
  • Apical secretion of Wnt1 in polarized epithelial cells is regulated by exocyst-mediated trafficking., Hideki Yamamoto,Akira Sato,Akira Kikuchi, Journal of biochemistry, OXFORD UNIV PRESS, Vol. 162, No. 5, p. 317-326, 2017/11/01
  • LDL switches the LRP6 internalization route from flotillin dependent to clathrin dependent in hepatic cells., Hideki Yamamoto,Daisuke Umeda,Shinji Matsumoto,Akira Kikuchi, Journal of cell science, COMPANY OF BIOLOGISTS LTD, Vol. 130, No. 20, p. 3542-3556, 2017/10/15
  • Two cases of endometrial cancer arising from adenomyosis during aromatase inhibitors therapy after mastectomy, Toru Yanase,Akira Kikuchi,Motoi Sasagawa,Shigeru Honma, JOURNAL OF OBSTETRICS AND GYNAECOLOGY, TAYLOR & FRANCIS INC, Vol. 37, No. 7, p. 952-954, 2017/10
  • The role of para-aortic lymphadenectomy in stage IIIC endometrial cancer: A single-institute study, Akira Kikuchi,Toru Yanase,Motoi Sasagawa,Shigeru Honma, JOURNAL OF OBSTETRICS AND GYNAECOLOGY, TAYLOR & FRANCIS INC, Vol. 37, No. 4, p. 510-513, 2017/05
  • Wnt5b-associated exosomes promote cancer cell migration and proliferation, Takeshi Harada,Hideki Yamamoto,Shosei Kishida,Michiko Kishida,Chihiro Awada,Toshifumi Takao,Akira Kikuchi, CANCER SCIENCE, WILEY-BLACKWELL, Vol. 108, No. 1, p. 42-52, 2017/01
  • Modulation of apical constriction by Wnt signaling is required for lung epithelial shape transition., Katsumi Fumoto,Hisako Takigawa-Imamura,Kenta Sumiyama,Tomoyuki Kaneiwa,Akira Kikuchi, Development (Cambridge, England), COMPANY OF BIOLOGISTS LTD, Vol. 144, No. 1, p. 151-162, 2017/01/01
  • Arl4c is a key regulator of tubulogenesis and tumourigenesis as a target gene of Wnt-β-catenin and growth factor-Ras signalling., Shinji Matsumoto,Shinsuke Fujii,Akira Kikuchi, Journal of biochemistry, OXFORD UNIV PRESS, Vol. 161, No. 1, p. 27-35, 2017/01
  • Epigenetic upregulation of ARL4C, due to DNA hypomethylation in the 3'-untranslated region, promotes tumorigenesis of lung squamous cell carcinoma., Shinsuke Fujii,Keiko Shinjo,Shinji Matsumoto,Takeshi Harada,Satoshi Nojima,Sunao Sato,Yu Usami,Satoru Toyosawa,Eiichi Morii,Yutaka Kondo,Akira Kikuchi, Oncotarget, IMPACT JOURNALS LLC, Vol. 7, No. 49, p. 81571-81587, 2016/12/06
  • h-Prune is associated with poor prognosis and epithelial-mesenchymal transition in patients with colorectal liver metastases, Masakazu Hashimoto,Tsuyoshi Kobayashi,Hirotaka Tashiro,Koji Arihiro,Akira Kikuchi,Hideki Ohdan, INTERNATIONAL JOURNAL OF CANCER, WILEY-BLACKWELL, Vol. 139, No. 4, p. 812-823, 2016/08
  • Prickle1 promotes focal adhesion disassembly in cooperation with the CLASP-LL5 beta complex in migrating cells, Boon Cheng Lim,Shinji Matsumoto,Hideki Yamamoto,Hiroki Mizuno,Junichi Kikuta,Masaru Ishii,Akira Kikuchi, JOURNAL OF CELL SCIENCE, COMPANY OF BIOLOGISTS LTD, Vol. 129, No. 16, p. 3115-3129, 2016/08
  • The WNT/MYB pathway suppresses KIT expression to control the timing of salivary proacinar differentiation and duct formation, Shinji Matsumoto,Takayuki Kurimoto,M. Mark Taketo,Shinsuke Fujii,Akira Kikuchi, DEVELOPMENT, COMPANY OF BIOLOGISTS LTD, Vol. 143, No. 13, p. 2311-2324, 2016/07
  • CKAP4 is a Dickkopf1 receptor and is involved in tumor progression., Hirokazu Kimura,Katsumi Fumoto,Kensaku Shojima,Satoshi Nojima,Yoshihito Osugi,Hideo Tomihara,Hidetoshi Eguchi,Yasushi Shintani,Hiroko Endo,Masahiro Inoue,Yuichiro Doki,Meinoshin Okumura,Eiichi Morii,Akira Kikuchi, The Journal of clinical investigation, Vol. 126, No. 7, p. 2689-705, 2016/07/01
  • h-prune affects anaplastic thyroid cancer invasion and metastasis, Junko Nambu,Tsuyoshi Kobayashi,Masakazu Hashimoto,Hirotaka Tashiro,Keizo Sugino,Fumio Shimamoto,Akira Kikuchi,Hideki Ohdan, ONCOLOGY REPORTS, SPANDIDOS PUBL LTD, Vol. 35, No. 6, p. 3445-3452, 2016/06
  • WNT5a is required for normal ovarian follicle development and antagonizes gonadotropin responsiveness in granulosa cells by suppressing canonical WNT signaling, Atefeh Abedini,Gustavo Zamberlam,Evelyne Lapointe,Catherine Tourigny,Alexandre Boyer,Marilene Paquet,Kanako Hayashi,Hiroaki Honda,Akira Kikuchi,Christopher Price,Derek Boerboom, FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, Vol. 30, No. 4, p. 1534-1547, 2016/04
  • Active and water-soluble form of lipidated Wnt protein is maintained by a serum glycoprotein afamin/alpha-albumin, Emiko Mihara,Hidenori Hirai,Hideki Yamamoto,Keiko Tamura-Kawakami,Mami Matano,Akira Kikuchi,Toshiro Sato,Junichi Takagi, ELIFE, ELIFE SCIENCES PUBLICATIONS LTD, Vol. 5, 2016/02
  • Disappearance of a metastatic brain tumor and achievement of long-term survival with a good quality of life after a combination of systemic chemotherapy with the P-glycoprotein inhibitor nifedipine in a patient with ovarian cancer, Toru Yanase,Akira Kikuchi,Motoi Sasagawa,Shigeru Honma, ACTA NEUROCHIRURGICA, SPRINGER WIEN, Vol. 157, No. 12, p. 2195-2197, 2015/12
  • Arl4c expression in colorectal and lung cancers promotes tumorigenesis and may represent a novel therapeutic target, S. Fujii,S. Matsumoto,S. Nojima,E. Morii,A. Kikuchi, ONCOGENE, NATURE PUBLISHING GROUP, Vol. 34, No. 37, p. 4834-4844, 2015/09
  • The P2Y(2) receptor promotes Wnt3a-and EGF-induced epithelial tubular formation by IEC6 cells by binding to integrins, Souji Ibuka,Shinji Matsumoto,Shinsuke Fujii,Akira Kikuchi, JOURNAL OF CELL SCIENCE, COMPANY OF BIOLOGISTS LTD, Vol. 128, No. 11, p. 2156-2168, 2015/06
  • The Wnt5a-Ror2 axis promotes the signaling circuit between interleukin-12 and interferon-gamma in colitis, Akira Sato,Hisako Kayama,Kensaku Shojima,Shinji Matsumoto,Hirofumi Koyama,Yasuhiro Minami,Satoshi Nojima,Eiichi Morii,Hiroaki Honda,Kiyoshi Takeda,Akira Kikuchi, SCIENTIFIC REPORTS, NATURE PUBLISHING GROUP, Vol. 5, 2015/06
  • Basolateral secretion of Wnt5a in polarized epithelial cells is required for apical lumen formation, Hideki Yamamoto,Chihiro Awada,Shinji Matsumoto,Tomoyuki Kaneiwa,Takayuki Sugimoto,Toshifumi Takao,Akira Kikuchi, JOURNAL OF CELL SCIENCE, COMPANY OF BIOLOGISTS LTD, Vol. 128, No. 5, p. 1051-1063, 2015/03
  • Wnt5a promotes cancer cell invasion and proliferation by receptor-mediated endocytosis-dependent and -independent mechanisms, respectively, Kensaku Shojima,Akira Sato,Hideaki Hanaki,Ikuko Tsujimoto,Masahiro Nakamura,Kazunari Hattori,Yuji Sato,Keiji Dohi,Michinari Hirata,Hideki Yamamoto,Akira Kikuchi, SCIENTIFIC REPORTS, NATURE PUBLISHING GROUP, Vol. 5, 2015/01
  • Modulation of Wnt Signaling by Endocytosis of Receptor Complexes, Akira Kikuchi,Shinji Matsumoto,Katsumi Fumoto,Akira Sato, Wnt Signaling in Development and Disease: Molecular Mechanisms and Biological Functions, Wiley Blackwell, p. 113-124, 2014/05/12
  • A combination of Wnt and growth factor signaling induces Arl4c expression to form epithelial tubular structures, Shinji Matsumoto,Shinsuke Fujii,Akira Sato,Souji Ibuka,Yoshinori Kagawa,Masaru Ishii,Akira Kikuchi, EMBO JOURNAL, WILEY-BLACKWELL, Vol. 33, No. 7, p. 702-718, 2014/04
  • IGFBP-4 is an inhibitor of canonical Wnt signalling required for cardiogenesis (vol 454, pg 345, 2008), Weidong Zhu,Ichiro Shiojima,Yuzuru Ito,Zhi Li,Hiroyuki Ikeda,Masashi Yoshida,Atsuhiko T. Naito,Jun-ichiro Nishi,Hiroo Ueno,Akihiro Umezawa,Tohru Minamino,Toshio Nagai,Akira Kikuchi,Makoto Asashima,Issei Komuro, NATURE, NATURE PUBLISHING GROUP, Vol. 506, No. 7487, p. 254-254, 2014/02
  • Wnt5a signaling promotes apical and basolateral polarization of single epithelial cells, Hidetoshi Gon,Katsumi Fumoto,Yonson Ku,Shinji Matsumoto,Akira Kikuchi, MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Vol. 24, No. 23, p. 3764-3774, 2013/12
  • Cell Cycle-Dependent Rho GTPase Activity Dynamically Regulates Cancer Cell Motility and Invasion In Vivo, Yoshinori Kagawa,Shinji Matsumoto,Yuji Kamioka,Koshi Mimori,Yoko Naito,Taeko Ishii,Daisuke Okuzaki,Naohiro Nishida,Sakae Maeda,Atsushi Naito,Junichi Kikuta,Keizo Nishikawa,Junichi Nishimura,Naotsugu Haraguchi,Ichiro Takemasa,Tsunekazu Mizushima,Masataka Ikeda,Hirofumi Yamamoto,Mitsugu Sekimoto,Hideshi Ishii,Yuichiro Doki,Michiyuki Matsuda,Akira Kikuchi,Masaki Mori,Masaru Ishii, PLOS ONE, PUBLIC LIBRARY SCIENCE, Vol. 8, No. 12, 2013/12
  • The apical and basolateral secretion of Wnt11 and Wnt3a in polarized epithelial cells is regulated by different mechanisms, Hideki Yamamoto,Chihiro Awada,Hideaki Hanaki,Hiroshi Sakane,Ikuko Tsujimoto,Yuko Takahashi,Toshifumi Takao,Akira Kikuchi, JOURNAL OF CELL SCIENCE, COMPANY OF BIOLOGISTS LTD, Vol. 126, No. 13, p. 2931-2943, 2013/07
  • [Canonical Wnt signaling pathway and cellular responses]., Kikuchi A, Clinical calcium, Vol. 23, No. 6, p. 799-807, 2013/06
  • Wnt5a signaling controls cytokinesis by correctly positioning ESCRT-III at the midbody, Katsumi Fumoto,Koji Kikuchi,Hidetoshi Gon,Akira Kikuchi, JOURNAL OF CELL SCIENCE, COMPANY OF BIOLOGISTS LTD, Vol. 125, No. 20, p. 4822-4832, 2012/10
  • An Anti-Wnt5a Antibody Suppresses Metastasis of Gastric Cancer Cells In Vivo by Inhibiting Receptor-Mediated Endocytosis, Hideaki Hanaki,Hideki Yamamoto,Hiroshi Sakane,Shinji Matsumoto,Hideki Ohdan,Akira Sato,Akira Kikuchi, MOLECULAR CANCER THERAPEUTICS, AMER ASSOC CANCER RESEARCH, Vol. 11, No. 2, p. 298-307, 2012/02
  • Regulation of focal adhesion dynamics by Wnt5a signaling, Shinji Matsumoto,Akira Kikuchi, Methods in Molecular Biology, Vol. 839, p. 215-227, 2012
  • Localization of glypican-4 in different membrane microdomains is involved in the regulation of Wnt signaling, Hiroshi Sakane,Hideki Yamamoto,Shinji Matsumoto,Akira Sato,Akira Kikuchi, JOURNAL OF CELL SCIENCE, COMPANY OF BIOLOGISTS LTD, Vol. 125, No. 2, p. 449-460, 2012/01
  • Waif1/5T4 Inhibits Wnt/β-Catenin Signaling and Activates Noncanonical Wnt Pathways by Modifying LRP6 Subcellular Localization, Birgit Kagermeier-Schenk,Daniel Wehner,Günes Özhan-Kizil,Hideki Yamamoto,Jian Li,Katharina Kirchner,Christian Hoffmann,Peter Stern,Akira Kikuchi,Alexandra Schambony,Gilbert Weidinger, Developmental Cell, Vol. 21, No. 6, p. 1129-1143, 2011/12/13
  • Insufficiency of BUBR1, a mitotic spindle checkpoint regulator, causes impaired ciliogenesis in vertebrates, Tatsuo Miyamoto,Sean Porazinski,Huijia Wang,Antonia Borovina,Brian Ciruna,Atsushi Shimizu,Tadashi Kajii,Akira Kikuchi,Makoto Furutani-Seiki,Shinya Matsuura, HUMAN MOLECULAR GENETICS, OXFORD UNIV PRESS, Vol. 20, No. 10, p. 2058-2070, 2011/05
  • Sumatriptan as a treatment for cyclic vomiting syndrome: A clinical trial, Toshiyuki Hikita,Hiroko Kodama,Sono Kaneko,Kaori Amakata,Kaori Ogita,Daishi Mochizuki,Fumiaya Kaga,Natsue Nakamoto,Yasushi Fujii,Akira Kikuchi, CEPHALALGIA, SAGE PUBLICATIONS LTD, Vol. 31, No. 4, p. 504-507, 2011/03
  • MMP-10/stromelysin-2 promotes invasion of head and neck cancer., Elsayed Mohamed Deraz,Yasusei Kudo,Maki Yoshida,Mariko Obayashi,Takaaki Tsunematsu,Hirotaka Tani,Samadarani B S M Siriwardena,Mohammad Reza Keikhaee,Guangying Qi,Shinji Iizuka,Ikuko Ogawa,Giuseppina Campisi,Lorenzo Lo Muzio,Yoshimitsu Abiko,Akira Kikuchi,Takashi Takata, PloS one, Vol. 6, No. 10, 2011
  • NEW INSIGHTS INTO THE MECHANISM OF WNT SIGNALING PATHWAY ACTIVATION, Akira Kikuchi,Hideki Yamamoto,Akira Sato,Shinji Matsumoto, INTERNATIONAL REVIEW OF CELL AND MOLECULAR BIOLOGY, VOL 291, ELSEVIER ACADEMIC PRESS INC, Vol. 291, p. 21-71, 2011
  • GSK3 regulates the expressions of human and mouse c-Myb via different mechanisms, Kyoko Kitagawa,Yojiro Kotake,Yoshihiro Hiramatsu,Ning Liu,Sayuri Suzuki,Satoki Nakamura,Akira Kikuchi,Masatoshi Kitagawa, CELL DIVISION, BIOMED CENTRAL LTD, Vol. 5, 2010/11
  • Dishevelled, a Wnt signalling component, is involved in mitotic progression in cooperation with Plk1, Koji Kikuchi,Yohei Niikura,Katsumi Kitagawa,Akira Kikuchi, EMBO JOURNAL, NATURE PUBLISHING GROUP, Vol. 29, No. 20, p. 3470-3483, 2010/10
  • Ror2/Frizzled complex mediates Wnt5a-induced AP-1 activation by regulating Dishevelled polymerization., Michiru Nishita,Sumiyo Itsukushima,Akira Nomachi,Mitsuharu Endo,ZhiChao Wang,Daisuke Inaba,Sen Qiao,Shinji Takada,Akira Kikuchi,Yasuhiro Minami, Molecular and cellular biology, Vol. 30, No. 14, p. 3610-9, 2010/07
  • Binding of APC and dishevelled mediates Wnt5a-regulated focal adhesion dynamics in migrating cells, Shinji Matsumoto,Katsumi Fumoto,Tetsuji Okamoto,Kozo Kaibuchi,Akira Kikuchi, EMBO JOURNAL, NATURE PUBLISHING GROUP, Vol. 29, No. 7, p. 1192-1204, 2010/04
  • LRP6 is internalized by Dkk1 to suppress its phosphorylation in the lipid raft and is recycled for reuse, Hiroshi Sakane,Hideki Yamamoto,Akira Kikuchi, Journal of Cell Science, Vol. 123, No. 3, p. 360-368, 2010/02/01
  • The PHCCEx domain of Tiam1/2 is a novel protein- and membrane-binding module, Shin-ichi Terawaki,Ken Kitano,Tomoyuki Mori,Yan Zhai,Yoshiki Higuchi,Norimichi Itoh,Takashi Watanabe,Kozo Kaibuchi,Toshio Hakoshima, EMBO JOURNAL, NATURE PUBLISHING GROUP, Vol. 29, No. 1, p. 236-250, 2010/01
  • Wnt5a regulates distinct signalling pathways by binding to Frizzled2, Akira Sato,Hideki Yamamoto,Hiroshi Sakane,Hirofumi Koyama,Akira Kikuchi, EMBO JOURNAL, WILEY, Vol. 29, No. 1, p. 41-54, 2010/01
  • Laminin gamma 2 Mediates Wnt5a-Induced Invasion of Gastric Cancer Cells, Hideki Yamamoto,Yasuhiko Kitadai,Hideki Yamamoto,Naohide Oue,Hideki Ohdan,Wataru Yasui,Akira Kikuchi, GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, Vol. 137, No. 1, p. 242-252, 2009/07
  • Axin localizes to the centrosome and is involved in microtubule nucleation, Katsumi Fumoto,Moe Kadono,Nanae Izumi,Akira Kikuchi, EMBO REPORTS, NATURE PUBLISHING GROUP, Vol. 10, No. 6, p. 606-613, 2009/06
  • H-prune is an independent prognostic marker for survival in Esophageal squamous cell carcinoma, Tsuyoshi Noguchi,Naohide Oue,Shinsuke Wada,Kazuhiro Sentani,Naoya Sakamoto,Akira Kikuchi,Wataru Yasui, Annals of Surgical Oncology, Vol. 16, No. 5, p. 1390-1396, 2009/05
  • Unc5B associates with LARG to mediate the action of repulsive guidance molecule, Katsuhiko Hata,Kozo Kaibuchi,Shinobu Inagaki,Toshihide Yamashita, JOURNAL OF CELL BIOLOGY, ROCKEFELLER UNIV PRESS, Vol. 184, No. 5, p. 737-750, 2009/03
  • Selective activation mechanisms of Wnt signaling pathways, Akira Kikuchi,Hideki Yamamoto,Akira Sato, TRENDS IN CELL BIOLOGY, ELSEVIER SCIENCE LONDON, Vol. 19, No. 3, p. 119-129, 2009/03
  • CHD8 suppresses p53-mediated apoptosis through histone H1 recruitment during early embryogenesis, Masaaki Nishiyama,Kiyotaka Oshikawa,Yu-ichi Tsukada,Tadashi Nakagawa,Shun-ichiro Iemura,Tohru Natsume,Yuhong Fan,Akira Kikuchi,Arthur I. Skoultchi,Keiichi I. Nakayama, NATURE CELL BIOLOGY, NATURE PUBLISHING GROUP, Vol. 11, No. 2, p. 172-U139, 2009/02
  • [Activation of the beta-catenin-independent pathway by Wnt and the diseases due to its abnormality]., Kikuchi A,Yamamoto H,Sato A, Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, Vol. 54, No. 1, p. 1-10, 2009/01
  • Wnt signaling; its abnormalities and diseases, Akira Kikuchi, Seikagaku, Vol. 81, No. 9, p. 780-792, 2009
  • IFN-Induced Transmembrane Protein 1 Promotes Invasion at Early Stage of Head and Neck Cancer Progression, Hiroko Hatano,Yasusei Kudo,Ikuko Ogawa,Takaaki Tsunematsu,Akira Kikuchi,Yoshimitsu Abiko,Takashi Takata, CLINICAL CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Vol. 14, No. 19, p. 6097-6105, 2008/10
  • AIP regulates stability of Aurora-A at early mitotic phase coordinately with GSK-3 beta, K. Fumoto,P-C Lee,H. Saya,A. Kikuchi, ONCOGENE, NATURE PUBLISHING GROUP, Vol. 27, No. 32, p. 4478-4487, 2008/07
  • IGFBP-4 is an inhibitor of canonical Wnt signalling required for cardiogenesis, Weidong Zhu,Ichiro Shiojima,Yuzuru Ito,Zhi Li,Hiroyuki Ikeda,Masashi Yoshida,Atsuhiko T. Naito,Jun-ichiro Nishi,Hiroo Ueno,Akihiro Umezawa,Tohru Minamino,Toshio Nagai,Akira Kikuchi,Makoto Asashima,Issei Komuro, NATURE, NATURE PUBLISHING GROUP, Vol. 454, No. 7202, p. 345-U51, 2008/07
  • Polycomb-group complex 1 acts as an E3 ubiquitin ligase for Geminin to sustain hematopoietic stem cell activity, Motoaki Ohtsubo,Shin'ichiro Yasunaga,Yoshinori Ohno,Miyuki Tsumura,Satoshi Okada,Nobutsune Ishikawa,Kenichiro Shirao,Akira Kikuchi,Hideo Nishitani,Masao Kobayashi,Yoshihiro Takihara, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, NATL ACAD SCIENCES, Vol. 105, No. 30, p. 10396-10401, 2008/07
  • Wnt3a and Dkk1 regulate distinct internalization pathways of LRP6 to tune the activation of beta-catenin signaling, Hideki Yamamoto,Hiroshi Sakane,Hideki Yamamoto,Tatsuo Michiue,Akira Kikuchi, DEVELOPMENTAL CELL, CELL PRESS, Vol. 15, No. 1, p. 37-48, 2008/07
  • GSK-3 beta regulates proper mitotic spindle formation in cooperation with a component of the gamma-tubulin ring complex, GCP5, Nanae Izumi,Katsumi Fumoto,Shunsuke Izumi,Akira Kikuchi, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 283, No. 19, p. 12981-12991, 2008/05
  • Tumor formation due to abnormalities in the beta-catenin-independent pathway of Wnt signaling, Akira Kikuchi,Hideki Yamamoto, CANCER SCIENCE, BLACKWELL PUBLISHING, Vol. 99, No. 2, p. 202-208, 2008/02
  • Wnt5a modulates glycogen synthase kinase 3 to induce phosphorylation of receptor tyrosine kinase Ror2., Hiroyuki Yamamoto,Sa Kan Yoo,Michiru Nishita,Akira Kikuchi,Yasuhiro Minami, Genes to cells : devoted to molecular & cellular mechanisms, Vol. 12, No. 11, p. 1215-23, 2007/11
  • Rho-kinase activation in endothelial cells contributes to expansion of infarction after focal cerebral ischemia, Yoshiki Yagita,Kazuo Kitagawa,Tsutomu Sasaki,Yasukazu Terasaki,Kenichi Todo,Emi Omura-Matsuoka,Kozo Kaibuchi,Masatsugu Hori, JOURNAL OF NEUROSCIENCE RESEARCH, WILEY-LISS, Vol. 85, No. 11, p. 2460-2469, 2007/08
  • Increased expression of h-prune is associated with tumor progression and poor survival in gastric cancer, Naohide Oue,Kazuhiro Yoshida,Tsuyoshi Noguchi,Kazuhiro Sentani,Akira Kikuchi,Wataru Yasui, CANCER SCIENCE, BLACKWELL PUBLISHING, Vol. 98, No. 8, p. 1198-1205, 2007/08
  • Structural basis for tubulin recognition by cytoplasmic linker protein 170 and its autoinhibition, Masaki Mishima,Ryoko Maesaki,Miyuki Kasa,Takashi Watanabe,Masaki Fukata,Kozo Kaibuchi,Toshio Hakoshima, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, NATL ACAD SCIENCES, Vol. 104, No. 25, p. 10346-10351, 2007/06
  • Noncovalent binding of small ubiquitin-related modifier (SUMO) protease to SUMO is necessary for enzymatic activities and cell growth., Motomasa Ihara,Hirofumi Koyama,Yasuhiro Uchimura,Hisato Saitoh,Akira Kikuchi, The Journal of biological chemistry, Vol. 282, No. 22, p. 16465-75, 2007/06/01
  • The DIX domain of Dishevelled confers Wnt signaling by dynamic polymerization, Thomas Schwarz-Romond,Marc Fiedler,Naoki Shibata,P. Jonathan G. Butler,Akira Kikuchi,Yoshiki Higuchi,Mariann Bienz, Nature Structural and Molecular Biology, Vol. 14, No. 6, p. 484-492, 2007/06
  • Multiplicity of the interactions of Wnt proteins and their receptors, Akira Kikuchi,Hideki Yamamoto,Shosei Kishida, CELLULAR SIGNALLING, ELSEVIER SCIENCE INC, Vol. 19, No. 4, p. 659-671, 2007/04
  • Post-translational palmitoylation and glycosylation of Wnt-5a are necessary for its signalling, Manabu Kurayoshi,Hideki Yamamoto,Shunsuke Izumi,Akira Kikuchi, BIOCHEMICAL JOURNAL, PORTLAND PRESS LTD, Vol. 402, p. 515-523, 2007/03
  • GSK-3 beta-regulated interaction of BICD with dynein is involved in microtubule anchorage at centrosome, Katsumi Fumoto,Casper C. Hoogenraad,Akira Kikuchi, EMBO JOURNAL, NATURE PUBLISHING GROUP, Vol. 25, No. 24, p. 5670-5682, 2006/12
  • Developmental stage-specific biphasic roles of Wnt/beta-catenin signaling in cardiomyogenesis and hematopoiesis, Atsuhiko T. Naito,Ichiro Shiojima,Hiroshi Akazawa,Kyoko Hidaka,Takayuki Morisaki,Akira Kikuchi,Issei Komuro, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, NATL ACAD SCIENCES, Vol. 103, No. 52, p. 19812-19817, 2006/12
  • Filopodia formation mediated by receptor tyrosine kinase Ror2 is required for Wnt5a-induced cell migration, Michiru Nishita,So Kan Yoo,Akira Nomachi,Shuichi Kani,Nagako Sougawa,Yasutaka Ohta,Shinji Takada,Akira Kikuchi,Yasuhiro Minami, JOURNAL OF CELL BIOLOGY, ROCKEFELLER UNIV PRESS, Vol. 175, No. 4, p. 555-562, 2006/11
  • Caveolin is necessary for Wnt-3a-dependent internalization of LRP6 and accumulation of beta-catenin, Hideki Yamamoto,Hideyuki Komekado,Akira Kikuchi, DEVELOPMENTAL CELL, CELL PRESS, Vol. 11, No. 2, p. 213-223, 2006/08
  • [Abnormal regulation of beta-catenin degradation through ubiquitination as a mechanism of carcinogenesis]., Kikuchi A,Kishida S, Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, Vol. 51, No. 10 Suppl, p. 1271-1276, 2006/08
  • Oog1, an oocyte-specific protein, interacts with Ras and Ras-signaling proteins during early embryogenesis, S Tsukamoto,R Ihara,A Aizawa,S Kishida,A Kikuchi,H Imai,N Minami, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 343, No. 4, p. 1105-1112, 2006/05
  • Regulation of Wnt signaling by protein-protein interaction and post-translational modifications, A Kikuchi,S Kishida,H Yamamoto, EXPERIMENTAL AND MOLECULAR MEDICINE, KOREAN SOC MED BIOCHEMISTRY MOLECULAR BIOLOGY, Vol. 38, No. 1, p. 1-10, 2006/02
  • Glycogen synthase kinase 3 and h-prune regulate cell migration by modulating focal adhesions, Tsuyoshi Kobayashi,Shin-Ichiro Hino,Naohide Oue,Toshimasa Asahara,Massimo Zollo,Wataru Yasui,Akira Kikuchi, Molecular and Cellular Biology, Vol. 26, No. 3, p. 898-911, 2006/02
  • Novel Daple-like protein positively regulates both the Wnt/beta-catenin pathway and the Wnt/JNK pathway in Xenopus, H Kobayashi,T Michiue,A Yukita,H Danno,K Sakurai,A Fukui,A Kikuchi,M Asashima, MECHANISMS OF DEVELOPMENT, ELSEVIER SCIENCE BV, Vol. 122, No. 10, p. 1138-1153, 2005/10
  • Phosphorylation of beta-catenin by cyclic AMP-dependent protein kinase stabilizes beta-catenin through inhibition of its ubiquitination, S Hino,C Tanji,KI Nakayama,A Kikuchi, MOLECULAR AND CELLULAR BIOLOGY, AMER SOC MICROBIOLOGY, Vol. 25, No. 20, p. 9063-9072, 2005/10
  • SUMO-1 modification of PIASy, an E3 ligase, is necessary for PIASy-dependent activation of Tcf-4, M Ihara,H Yamamoto,A Kikuchi, MOLECULAR AND CELLULAR BIOLOGY, AMER SOC MICROBIOLOGY, Vol. 25, No. 9, p. 3506-3518, 2005/05
  • Ubquitin-interacting motifs of epsin are involved in the regulation of insulin-dependent endocytosis, S Sugiyama,S Kishida,K Chayama,S Koyama,A Kikuchi, JOURNAL OF BIOCHEMISTRY, JAPANESE BIOCHEMICAL SOC, Vol. 137, No. 3, p. 355-364, 2005/03
  • GSK-3β regulates phosphorylation of CRMP-2 and neuronal polarity, Takeshi Yoshimura,Yoji Kawano,Nariko Arimura,Saeko Kawabata,Akira Kikuchi,Kozo Kaibuchi, Cell, Vol. 120, No. 1, p. 137-149, 2005/01/14
  • The receptor tyrosine kinase Ror2 associates with and is activated by casein kinase Iepsilon., Shuichi Kani,Isao Oishi,Hiroyuki Yamamoto,Akinori Yoda,Hiroaki Suzuki,Akira Nomachi,Kengo Iozumi,Michiru Nishita,Akira Kikuchi,Toru Takumi,Yasuhiro Minami, The Journal of biological chemistry, 48, Vol. 279, No. 48, p. 50102-9, 2004/11/26
  • Small ubiquitin-like modifier 1 (SUMO-1) modification of the synergy control motif of Ad4 binding protein/steroidogenic factor 1 (Ad4BP/SF-1) regulates synergistic transcription between Ad4BP/SF-1 and Sox9, T Komatsu,H Mizusaki,T Mukai,H Ogawa,D Baba,M Shirakawa,S Hatakeyama,KI Nakayama,H Yamamoto,A Kikuchi,KI Morohashi, MOLECULAR ENDOCRINOLOGY, ENDOCRINE SOC, Vol. 18, No. 10, p. 2451-2462, 2004/10
  • Early embryonic death in mice lacking the beta-catenin-binding protein duplin, M Nishiyama,K Nakayama,R Tsunematsu,T Tsukiyama,A Kikuchi,KI Nakayama, MOLECULAR AND CELLULAR BIOLOGY, AMER SOC MICROBIOLOGY, Vol. 24, No. 19, p. 8386-8394, 2004/10
  • Mesenchymal-epithelial transition during somitic segmentation is regulated by differential roles of Cdc42 and Rac1, Y Nakaya,S Kuroda,YT Katagiri,K Kaibuchi,Y Takahashi, DEVELOPMENTAL CELL, CELL PRESS, Vol. 7, No. 3, p. 425-438, 2004/09
  • XSENP1, a novel sumo-specific protease in Xenopus, inhibits normal head formation by down-regulation of Wnt/beta-catenin signalling, A Yukita,T Michiue,A Fukui,K Sakurai,H Yamamoto,M Ihara,A Kikuchi,M Asashima, GENES TO CELLS, BLACKWELL PUBLISHING LTD, Vol. 9, No. 8, p. 723-736, 2004/08
  • Sall1, a causative gene for Townes-Brocks syndrome, enhances the canonical Wnt signaling by localizing to heterochromatin, A Sato,S Kishida,T Tanaka,A Kikuchi,T Kodama,M Asashima,R Nishinakamura, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 319, No. 1, p. 103-113, 2004/06
  • Wnt-3a and Dvl induce neurite retraction by activating Rho-associated kinase, S Kishida,H Yamamoto,A Kikuchi, MOLECULAR AND CELLULAR BIOLOGY, AMER SOC MICROBIOLOGY, Vol. 24, No. 10, p. 4487-4501, 2004/05
  • Xldax, an inhibitor of the canonical Wnt pathway, is required for anterior neural structure formation in Xenopus, T Michiue,A Fukui,A Yukita,K Sakurai,H Danno,A Kikuchi,M Asashima, DEVELOPMENTAL DYNAMICS, WILEY-LISS, Vol. 230, No. 1, p. 79-90, 2004/05
  • Inhibition of the canonical Wnt signaling pathway in cytoplasm: a novel property of the carboxyl terminal domains of two Xenopus ELL genes, K Sakurai,T Michiue,A Kikuchi,M Asashima, ZOOLOGICAL SCIENCE, ZOOLOGICAL SOC JAPAN, Vol. 21, No. 4, p. 407-416, 2004/04
  • Positive role of IQGAP1, an effector of Rac1, in actin-meshwork formation at sites of cell-cell contact, J Noritake,M Fukata,K Sato,M Nakagawa,T Watanabe,N Izumi,SJ Wang,Y Fukata,K Kaibuchi, MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Vol. 15, No. 3, p. 1065-1076, 2004/03
  • Identification and characterization of a novel Dvl-binding protein that suppresses Wnt signalling pathway, A Oshita,S Kishida,H Kobayashi,T Michiue,T Asahara,M Asashima,A Kikuchi, GENES TO CELLS, BLACKWELL PUBLISHING LTD, Vol. 8, No. 12, p. 1005-1017, 2003/12
  • Roles of Rho-family GTPases in cell polarisation and directional migration, M Fukata,M Nakagawa,K Kaibuchi, CURRENT OPINION IN CELL BIOLOGY, CURRENT BIOLOGY LTD, Vol. 15, No. 5, p. 590-597, 2003/10
  • Impaired degradation of inhibitory subunit of NF-kappa B (I kappa B) and beta-catenin as a result of targeted disruption of the beta-TrCP1 gene, K Nakayama,S Hatakeyama,S Maruyama,A Kikuchi,K Onoe,RA Good,KI Nakayama, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, NATL ACAD SCIENCES, Vol. 100, No. 15, p. 8752-8757, 2003/07
  • Regulation of type 1 protein phosphatase/inhibitor-2 complex by glycogen synthase kinase-3 beta in intact cells, G Sakashita,H Shima,M Komatsu,T Urano,A Kikuchi,K Kikuchi, JOURNAL OF BIOCHEMISTRY, JAPANESE BIOCHEMICAL SOC, Vol. 133, No. 2, p. 165-171, 2003/02
  • PY motifs of Rod1 are required for binding to Rsp5 and for drug resistance, T Andoh,Y Hirata,A Kikuchi, FEBS LETTERS, ELSEVIER SCIENCE BV, Vol. 525, No. 1-3, p. 131-134, 2002/08
  • Rac1 and Cdc42 capture microtubules through IQGAP1 and CLIP-170, M Fukata,T Watanabe,J Noritake,M Nakagawa,M Yamaga,S Kuroda,Y Matsuura,A Iwamatsu,F Perez,K Kaibuchi, CELL, CELL PRESS, Vol. 109, No. 7, p. 873-885, 2002/06
  • Rho-family GTPases in cadherin-mediated cell-cell adhesion, M Fukata,K Kaibuchi, NATURE REVIEWS MOLECULAR CELL BIOLOGY, NATURE PUBLISHING GROUP, Vol. 2, No. 12, p. 887-897, 2001/12
  • Recruitment and activation of Rac1 by the formation of E-cadherin-mediated cell-cell adhesion sites, M Nakagawa,M Fukata,M Yamaga,N Itoh,K Kaibuchi, JOURNAL OF CELL SCIENCE, COMPANY OF BIOLOGISTS LTD, Vol. 114, No. 10, p. 1829-1838, 2001/05
  • Involvement of IQGAP1, an effector of Rac1 and Cdc42 GTPases, in cell-cell dissociation during cell scattering, M Fukata,M Nakagawa,N Itoh,A Kawajiri,M Yamaga,S Kuroda,K Kaibuchi, MOLECULAR AND CELLULAR BIOLOGY, AMER SOC MICROBIOLOGY, Vol. 21, No. 6, p. 2165-2183, 2001/03
  • Identification of a novel beta-catenin-interacting protein, A Kawajiri,N Itoh,M Fukata,M Nakagawa,M Yamaga,A Iwamatsu,K Kaibuchi, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC, Vol. 273, No. 2, p. 712-717, 2000/07
  • Phosphorylation of ERM proteins at filopodia induced by Cdc42, N Nakamura,N Oshiro,Y Fukata,M Amano,M Fukata,S Kuroda,Y Matsuura,T Leung,L Lim,K Kaibuchi, GENES TO CELLS, WILEY-BLACKWELL, Vol. 5, No. 7, p. 571-581, 2000/07
  • Phosphorylation of adducin by Rho-kinase plays a crucial role in cell motility, Yuko Fukata,Noriko Oshiro,Nagatoki Kinoshita,Yoji Kawano,Yoichiro Matsuoka,Vann Bennett,Yoshiharu Matsuura,Kozo Kaibuchi, Journal of Cell Biology, Vol. 145, No. 2, p. 347-361, 2000/06
  • GSK-3 beta-dependent phosphorylation of adenomatous polyposis coli gene product can be modulated by beta-catenin and protein phosphatase 2A complexed with Axin, S Ikeda,M Kishida,Y Matsuura,H Usui,A Kikuchi, ONCOGENE, STOCKTON PRESS, Vol. 19, No. 4, p. 537-545, 2000/01
  • Cell adhesion and Rho small GTPases, M Fukata,M Nakagawa,S Kuroda,K Kaibuchi, JOURNAL OF CELL SCIENCE, COMPANY OF BIOLOGISTS LTD, Vol. 112, No. 24, p. 4491-4500, 1999/12
  • Regulation of cadherin-mediated cell-cell adhesion by the Rho family GTPases, K Kaibuchi,S Kuroda,M Fukata,M Nakagawa, CURRENT OPINION IN CELL BIOLOGY, CURRENT BIOLOGY LTD, Vol. 11, No. 5, p. 591-596, 1999/10
  • Cdc42, Rac1, and their effector IQGAP1 as molecular switches for cadherin-mediated cell-cell adhesion, S Kuroda,M Fukata,M Nakagawa,K Kaibuchi, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC, Vol. 262, No. 1, p. 1-6, 1999/08
  • β-カテニンのユビキチン化に関わる分子FWD1の同定と機能解析, 北川雅敏,畠山鎮次,菊池章,中山啓子,中山敬一, 日本癌学会58回総会記事, p. 79-79, 1999/08
  • Localization of the gene coding for ROCK II Rho kinase on human chromosome 2p24, N Takahashi,H Tuiki,H Saya,K Kaibuchi, GENOMICS, ACADEMIC PRESS INC, Vol. 55, No. 2, p. 235-237, 1999/01
  • Regulation of the association of adducin with actin filaments by Rho- associated kinase (Rho-kinase) and myosin phosphatase, Kimura K,Fukata Y,Matsuoka Y,Bennett V,Matsuura Y,Okawa K,Iwamatsu A,Kaibuchi K, J Biol Chem, Vol. 273, p. 5542-5548, 1998/03
  • Regulation of cell-cell adhesion of MDCK cells by Cdc42 and Rac1 small GTPases, S Kuroda,M Fukata,K Fujii,T Nakamura,Izawa, I,K Kaibuchi, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS, Vol. 240, No. 2, p. 430-435, 1997/11
  • DIFFERENT FUNCTIONS OF SMG GDP DISSOCIATION STIMULATOR AND MAMMALIAN COUNTERPART OF YEAST CDC25, H NAKANISHI,K KAIBUCHI,S ORITA,N UENO,Y TAKAI, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 269, No. 21, p. 15085-15091, 1994/05
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Misc.

  • DKK1受容体CKAP4のパルミチン酸化を介したシグナル制御機構, 2019/12
  • DKK1-CKAP4シグナルと転写因子FOXM1のpositive feedback loop形成機構, 2019/12
  • 肝腫瘍に対するARL4Cを標的としたアンチセンス核酸を用いた新規がん治療法の開発, Vol. 92回, p. [2P-284], 2019/09
  • DKK1 signal-dependent cellular functions through two receptors, LRP6 and CKAP4., 2019/06
  • The DKK1-CKAP4 signaling pathway as a novel therapeutic target for cancers., Kimura H,Fumoto K,Kikuchi A, Australia Japan Medical Research Symposium, 2018/09
  • がん特性の解明に迫るシグナル伝達研究 新規がんシグナルDickkopf1-CKAP4経路は、がん治療のための分子標的となる(Signal transduction analysis for cancer profiling The Dickkopf1-CKAP4 pathway, a novel cancer signaling, represents molecular targets for cancer therapy), 菊池 章,木村 公一,麓 勝己, 日本癌学会総会記事, 日本癌学会, Vol. 77回, p. 1768-1768, 2018/09
  • DKK1の新規受容体であるCKAP4のエクソソームへの移行機構の解析, Vol. 91回, p. [1T13e-162)], 2018/09
  • CKAP4の動的なパルミチン酸化修飾は癌細胞の膜マイクロドメイン形成と増殖シグナル伝達活性を調節する(Dynamic palmitoylation regulates membrane microdomain localization and cancer cell proliferative signaling activity of CKAP4), Vol. 91回, p. [3T11m-095)], 2018/09
  • 唾液腺におけるWntシグナル依存性新規前駆細胞の同定と機能解析, 松本真司,廣田傑,廣田傑,菊池章, Journal of Oral Biosciences Supplement (Web), Vol. 2018, 2018
  • DickkopfファミリーによるCKAP4を介したがん細胞増殖調節機構, Vol. 2017年度, p. [1P-1007], 2017/12
  • CKAP4の脂質修飾を介する機能制御, Vol. 2017年度, p. [4P1T25-0164)], 2017/12
  • Wnt Signaling Induces Factor X to Promote Tumorigenesis of Hepatoblastoma, Taku Yamamichi,Shinji Matsumoto,Akira Kikuchi,Hiroomi Okuyama, PEDIATRIC BLOOD & CANCER, WILEY, Vol. 64, p. S64-S64, 2017/11
  • がん分子標的治療薬の分子基盤と臨床応用 DKK1の新規受容体CKAP4を標的とする抗がん剤開発, 菊池 章,木村 公一,麓 勝己,大杉 祥仁, 日本癌学会総会記事, 日本癌学会, Vol. 76回, p. S5-1, 2017/09
  • 食道扁平上皮癌の新規治療標的であるDKK1-CKAP4シグナル, 木村 公一,新野 直樹,佐田 遼太,麓 勝己,菊池 章, 日本癌学会総会記事, 日本癌学会, Vol. 76回, p. J-2059, 2017/09
  • CKAP4の翻訳後修飾を介する機能制御, 2017/05
  • 膵癌の新規治療標的であるDkk1新規受容体CKAP4, Vol. 32, No. 3, p. 502-502, 2017/05
  • 腸管炎症関連疾患におけるWnt5aの機能解析, 前原奈都美,佐藤朗,麓勝己,菊池章, 日本生化学会大会(Web), Vol. 90th, 2017
  • Wnt5b含有エクソソームは癌細胞の増殖及び運動能を亢進させる, 原田武志,山本英樹,菊池章, 日本生化学会大会(Web), Vol. 90th, 2017
  • Wnt/Rasシグナル標的因子Arl4cの膵癌における機能, 松本真司,赤間俊之,庄嶋健作,菊池章, 日本生化学会大会(Web), Vol. 90th, 2017
  • Wntシグナルによる頂端膜収縮の調節は肺分岐構造と肺胞形成を制御する, 麓勝己,今村寿子,菊池章, 日本生化学会大会(Web), Vol. 90th, 2017
  • 成体唾液腺におけるWntシグナル応答細胞の同定と機能解析, 廣田傑,廣田傑,松本真司,菊池章, 日本生化学会大会(Web), Vol. 90th, 2017
  • 新規癌治療標的であるDkk1-CKAP4シグナル, 木村 公一,麓 勝己,庄嶋 健作,大杉 祥仁,菊池 章, 日本癌学会総会記事, 日本癌学会, Vol. 75回, p. IS2-5, 2016/10
  • WntシグナルにおけるFrizzled受容体の活性化機構, 山本英樹,菊池章, 医学のあゆみ, Vol. 256, No. 5, 2016/01/30
  • Activation mechanism of Frizzled receptor in Wnt signaling, 山本 英樹,菊池 章, 医学のあゆみ, 医歯薬出版, Vol. 256, No. 5, p. 421-429, 2016/01/30
  • エキソソーム上のWnt5bは細胞環境に応じて,がん細胞の増殖と運動を制御する, 原田武志,山本英樹,菊池章, 日本生化学会大会(Web), Vol. 89th, 2016
  • WntとKITシグナルの活性化バランスによる唾液腺の形づくりと機能獲得過程の制御, 松本真司,栗本聖之,藤井慎介,菊池章, Journal of Oral Biosciences Supplement (Web), Vol. 2016, 2016
  • Wnt5aシグナルは炎症を背景とした大腸がん形成に促進的に作用する, 佐藤朗,佐藤朗,前原奈都美,扇田久和,菊池章, 日本分子生物学会年会プログラム・要旨集(Web), Vol. 39th, 2016
  • Wntシグナルによる頂端膜収縮の調節は肺分岐構造と肺胞形成を制御する, 麓勝己,今村(滝川)寿子,菊池章, 日本分子生物学会年会プログラム・要旨集(Web), Vol. 39th, 2016
  • Wnt5a-Ror2シグナルによる腸管炎症の増悪機構の解析, 佐藤 朗,香山 尚子,庄嶋 健作,松本 真司,小山 浩史,南 康博,野島 聡,森井 英一,本田 浩章,竹田 潔,菊池 章, 日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, (公社)日本生化学会, Vol. 88回・38回, p. [1P0170]-[1P0170], 2015/12
  • 上皮管腔形成研究を基盤にしたがん治療のための新規標的分子の同定, 菊池 章,藤井 慎介,木村 公一,麓 勝巳,松本 真司, 日本癌学会総会記事, 日本癌学会, Vol. 74回, p. ML2-ML2, 2015/10
  • Dkk1新規受容体CKAP4は膵癌および肺癌の治療標的分子である, 木村 公一,麓 勝己,菊池 章, 日本癌学会総会記事, 日本癌学会, Vol. 74回, p. J-1295, 2015/10
  • Wnt/β‐カテニンシグナルは唾液腺上皮の腺房分化を制御する, 栗本聖之,栗本聖之,松本真司,藤井慎介,菊池章,古郷幹彦, 日本口腔科学会雑誌, Vol. 64, No. 2, 2015/07/10
  • Wnt5aシグナル伝達―その異常のがんと炎症における意義―, 菊池章,山本英樹,佐藤朗,松本真司, 日本整形外科学会雑誌, Vol. 89, No. 6, 2015/06/05
  • Wnt3aとEGFシグナルによって発現するP2Y<sub>2</sub>Rは上皮管腔形成を制御する, 井深奏司,松本真司,藤井慎介,菊池章,奥山宏臣, 日本小児外科学会雑誌, Vol. 51, No. 3, 2015/05/25
  • Wnt5aの極性分泌による上皮細胞の内腔形成制御機構, 山本英樹,粟田ちひろ,高尾敏文,菊池章, 日本生化学会大会(Web), Vol. 88th, 2015
  • Wnt/β‐カテニンシグナルは終末部上皮の腺房化の調節を介して胎生期唾液腺の形態形成を制御する, 松本真司,栗本聖之,藤井慎介,菊池章, 日本生化学会大会(Web), Vol. 88th, 2015
  • Wnt5bの細胞外分泌機構とその生理機能の解析, 原田武志,山本英樹,菊池章, 日本生化学会大会(Web), Vol. 88th, 2015
  • ヒトがんにおける低分子量G蛋白質Arl4cの異常と機能, Vol. 29, p. 1-5, 2015
  • がんと脂質 分子メカニズムへ 2.Wntの脂質修飾を標的にしたがん創薬, 山本英樹,菊池章, Lipid, Vol. 25, No. 4, p. 384-390, 2014/10/10
  • DKK1による細胞増殖調節機構, Vol. 87回, p. [3P-323], 2014/10
  • Wnt5a-Ror2シグナルによる腸管炎症の増悪機構の解析, 佐藤 朗,香山 尚子,庄嶋 健作,松本 真司,小山 浩史,南 康博,野島 聡,森井 英一,本田 浩章,竹田 潔,菊池 章, 日本生化学会大会プログラム・講演要旨集, (公社)日本生化学会, Vol. 87回, p. [2T09p-07], 2014/10
  • OP-056-5 大腸癌肝転移の予後因子としてのh-prune(OP-056 肝 転移性肝癌-2,一般演題,第114回日本外科学会定期学術集会), Vol. 115, No. 2, 2014/03/05
  • Wnt/β‐カテニンシグナルは外分泌腺上皮の分岐と導管形成を制御する, 松本真司,栗本聖之,藤井慎介,菊池章, 日本生化学会大会(Web), Vol. 87th, 2014
  • 極性化された上皮細胞におけるWntとその受容体の輸送制御機構, 山本英樹,金岩知之,粟田ちひろ,高尾敏文,菊池章, 日本生化学会大会(Web), Vol. 87th, 2014
  • Wnt/EGFシグナルにより発現するP2ry2は上皮管腔形態形成を制御する, 井深奏司,松本真司,菊池章, 日本生化学会大会(Web), Vol. 87th, 2014
  • 翻訳後修飾によるWnt5aの細胞外分泌の制御機構, 杉本崇行,山本英樹,粟田ちひろ,高尾敏文,坂根洋,菊池章, 日本生化学会大会(Web), Vol. 87th, 2014
  • Wntシグナルによる肺分岐形態形成制御機構, 麓勝己,金岩知之,菊池章, 日本生化学会大会(Web), Vol. 87th, 2014
  • 上皮細胞頂底極性制御におけるWntシグナル構成因子Dvlの役割, 原田昭和,麓勝己,菊池章, 日本生化学会大会(Web), Vol. 87th, 2014
  • 細胞接着の制御 Wnt 5aシグナルによる細胞の極性と遊走・接着の制御, 松本真司,菊池章, 生体の科学, Vol. 64, No. 3, p. 226-231, 2013/06/15
  • Wntシグナルと骨 古典的Wntシグナルの情報伝達と細胞応答, 菊池章, Clin Calcium, Vol. 23, No. 6, p. 799-807, 2013/05/28
  • Role of Wnt 5a signaling in the regulation of cell polarity, migration, and adhesion, 松本 真司,菊池 章, 生体の科学, 金原一郎記念医学医療振興財団 ; 1949-, Vol. 64, No. 3, p. 226-231, 2013/05
  • Wnt協奏曲:新たな活性化機構と他の増殖・分化シグナルとの協調による形態形成 基礎の基礎 Wnt研究のこれまでとこれから~過去・現在・未来~, 菊池章, 細胞工学, Vol. 32, No. 4, p. 382-387, 2013/03/22
  • Wnt協奏曲:新たな活性化機構と他の増殖・分化シグナルとの協調による形態形成【第1部:Wntシグナル活性化の新機軸】極性化上皮細胞におけるWntの分泌制御, 山本英樹,菊池章, 細胞工学, Vol. 32, No. 4, p. 388-395, 2013/03/22
  • Wnt協奏曲:新たな活性化機構と他の増殖・分化シグナルとの協調による形態形成【第2部:Wntシグナルと幹細胞からの組織形態形成】Wntと増殖因子の協調的シグナルによる上皮管腔組織形成, 松本真司,菊池章, 細胞工学, Vol. 32, No. 4, p. 435-441, 2013/03/22
  • Wntと細胞増殖シグナルの協調的作用による上皮管腔組織形成の分子機構, 菊池章,松本真司,藤井慎介,井深泰司, 再生医療, Vol. 12, 2013/02/28
  • Wnt5aシグナルは基底膜誘導性の単一細胞レベルでの頂底極性形成を制御する, 権英寿,麓勝己,菊池章, 日本生化学会大会(Web), Vol. 86th, 2013
  • Wnt/β‐cateninシグナル経路は唾液腺上皮の発生を制御する, 藤井慎介,松本真司,菊池章, 日本分子生物学会年会プログラム・要旨集(Web), Vol. 36th, 2013
  • Wnt/EGFシグナルによるP2ry2の発現は上皮管腔形態形成を制御する, 井深奏司,松本真司,菊池章, 日本分子生物学会年会プログラム・要旨集(Web), Vol. 36th, 2013
  • 肺分岐形態形成におけるWntシグナルによる分裂軸制御機構及び生理的意義, 麓勝己,菊池章, 日本分子生物学会年会プログラム・要旨集(Web), Vol. 36th, 2013
  • 極性化された上皮細胞におけるWntの分泌制御機構, 山本英樹,花木英明,辻本育子,金岩知之,粟田ちひろ,高尾敏文,菊池章, 日本生化学会大会(Web), Vol. 86th, 2013
  • Wnt5aノックアウトマウスにおける腸管炎症の抑制, 佐藤朗,庄嶋健作,香山尚子,小山浩史,竹田潔,菊池章, 日本分子生物学会年会プログラム・要旨集(Web), Vol. 36th, 2013
  • Regulation of Secretion of Wnts in Polarized Epithelial Cells, 山本 英樹,菊池 章, 細胞工学, 学研メディカル秀潤社 ; 1982-, Vol. 32, No. 4, p. 388-395, 2013
  • Wnt Regulates Epithelial Tubular Structure in Cooperation with Growth Factor Signalling, 松本 真司,菊池 章, 細胞工学, 学研メディカル秀潤社 ; 1982-, Vol. 32, No. 4, p. 435-441, 2013
  • Wntシグナル伝達経路で機能するDIXドメインを介した相互作用の構造生物学, 勝谷拓也,寺脇慎一,柴田直樹,山本英樹,FIEDLER Marc,BIENZ Mariann,菊池章,樋口芳樹, 日本結晶学会年会講演要旨集, Vol. 2012, 2012/10/25
  • 細胞周期制御の新展開 新規細胞周期依存性RhoGAP「Celmobilin」によるヒト癌細胞の遊走と浸潤の制御(New aspect of cell cycle research and cancer A novel cell cycle-associated RhoGAP, Celmobilin, regulates cancer cell motility and invasion in human), 賀川 義規,西川 恵三,前田 栄,松本 真司,奥崎 大介,三森 功士,山本 浩文,関本 貢嗣,菊池 章,石井 秀始,土岐 祐一郎,森 正樹,石井 優, 日本癌学会総会記事, 日本癌学会, Vol. 71回, p. 94-94, 2012/08
  • シグナル伝達の破綻と疾患との連関 7.Wntシグナルの異常と消化器がん, 菊池章,松本真司, 実験医学, Vol. 30, No. 5, p. 823-830, 2012/03/25
  • Wnt5aシグナルによる細胞質分裂制御機構, 麓勝己,菊池浩二,菊池章, 日本分子生物学会年会プログラム・要旨集(Web), Vol. 35th, 2012
  • Wnt5aノックアウトマウスにおける腸管炎症の抑制, 佐藤朗,庄嶋健作,小山浩史,菊池章, 日本分子生物学会年会プログラム・要旨集(Web), Vol. 35th, 2012
  • 翻訳後修飾によるWnt11の機能発現の制御, 山本英樹,花木英明,辻本育子,粟田ちひろ,高尾敏文,菊池章, 日本生化学会大会(Web), Vol. 85th, 2012
  • Wnt/β‐cateninシグナルとEGFシグナルの協調による三次元基質内での上皮分岐管腔形成制御機構の解析, 松本真司,藤井慎介,井深奏司,菊池章, 日本分子生物学会年会プログラム・要旨集(Web), Vol. 35th, 2012
  • がんにおける分子標的としてのWnt5a, 菊池章, がん研究分野の特性等を踏まえた支援活動合同公開シンポジウムプログラム・抄録集 平成24年, 2012
  • 3次元基底膜マトリックス誘導性の単一細胞レベルでの頂底極性形成におけるWnt5aシグナルの役割, 権英寿,麓勝己,菊池章, 日本生化学会大会(Web), Vol. 85th, 2012
  • 基底膜蛋白質Nidogen‐1はWnt3aと結合しWnt/βカテニン経路の活性化を促進する, 藤井慎介,松本真司,佐藤祐哉,下野知性,関口清俊,菊池章, 日本生化学会大会(Web), Vol. 85th, 2012
  • Wntシグナルによる上皮形態形成制御とその異常による病態, 菊池章, 日本内分泌学会雑誌, Vol. 87, No. 1, 2011/04/01
  • 基礎研究編:発癌から浸潤・転移に至るメカニズム解明 第1章 発癌シグナルの原因究明 2.Wntシグナルネットワークの異常と癌, 菊池章,佐藤朗,松本真司, 実験医学, Vol. 29, No. 2, p. 170-179, 2011/02/01
  • Glypican‐4の脂質ラフトへの局在に依存したWntシグナル伝達の制御機構, 坂根洋,山本英樹,松本真司,佐藤朗,菊池章, 生化学, 2011
  • 翻訳後修飾によるWnt蛋白質の機能発現の制御, 山本英樹,粟田ちひろ,高尾敏文,岸田昭世,岸田想子,菊池章, 生化学, 2011
  • Wnt signaling pathways regulate epithelial polarity and morphogenesis, Shinji Matsumoto,Akira Kikuchi, DIFFERENTIATION, ELSEVIER SCI LTD, Vol. 80, p. S21-S21, 2010/11
  • 造血細胞におけるWnt5aの欠失はp210BCR/ABLによって引き起こされるCMLを増悪させる(Loss of Wnt5a in hematopoietic cells exacerbate Chronic Myelogenous Leukemia induced by p210BCR/ABL fusion protein), 稲垣 舞子,小山 浩史,菊池 章,本田 浩章, 日本癌学会総会記事, 日本癌学会, Vol. 69回, p. 113-113, 2010/08
  • Wntシグナルと細胞応答 細胞周期制御におけるWntシグナルの役割, 菊池浩二,菊池章, 医学のあゆみ, Vol. 233, No. 10, p. 960-965, 2010/06/05
  • Wntシグナルと細胞応答 Wntシグナル経路の多様性と選択的活性化, 山本英樹,菊池章, 医学のあゆみ, Vol. 233, No. 10, p. 948-954, 2010/06/05
  • Selective activation of multiple Wnt signaling pathways, 山本 英樹,菊池 章, 医学のあゆみ, 医歯薬出版, Vol. 233, No. 10, p. 948-954, 2010/06/05
  • Wnt5aによるDishevelled/Adenomatous polyposis coli複合体を介した細胞接着と細胞運動の制御, 松本真司,岡本哲治,菊池章, 組織培養研究, Vol. 29, No. 1, 2010/03/31
  • Wnt‐5aはlaminin g2の発現を誘導し,胃癌細胞の浸潤を促進する, 大上直秀,菊池章,安井弥, 日本病理学会会誌, Vol. 99, No. 1, 2010/03/26
  • β-catenin-independent Wnt signaling regulates cell migration, polarity, and morphogenesis, MATSUMOTO Shinji,OKAMOTO Tetsuji,KIKUCHI Akira, TISSUE CULTURE RESEARCH COMMUNICATIONS, 日本組織培養学会, Vol. 28, No. 2, p. 117-128, 2009/12/31
  • 造血幹細胞の自己複製におけるβカテニン非依存的Wntシグナルの役割, 岡村敏志,大江原淳,山崎聡,菊池章,中内啓光,依馬秀夫, 臨床血液, Vol. 50, No. 9, 2009/09/30
  • Wnt5aによるDishevelled/Adenomatous polyposis coli複合体を介した細胞接着と細胞運動の制御, 松本真司,菊池章, 生化学, 2009/09/25
  • DKK1によるLRP6のエンドサイトーシスを介するWntシグナル伝達の制御, 坂根洋,山本英樹,菊池章, 生化学, 2009/09/25
  • Wntシグナルネットワークとその異常による病態, 菊池章, 生化学, Vol. 81, No. 9, p. 780-792, 2009/09/25
  • 異なる受容体エンドサイトーシス経路を介するWntシグナル伝達の制御機構, 山本英樹,坂根洋,菊池章, 生化学, 2009/09/25
  • Wntシグナル関連分子Dishevelledによる上皮極性・形態形成制御機構についての解析, 松本真司,菊池章,岡本哲治, 組織培養研究, Vol. 28, No. 1, 2009/03/31
  • Axin‐Testis derived transcript複合体の解析, 上田茂之,佐藤朗,岡本健吾,藤原誠,松本真司,菊池浩二,小山浩史,菊池章, 日本分子生物学会年会講演要旨集, Vol. 32nd, No. Vol.1, 2009
  • .BETA.-catenin-independent Wnt signaling regulates cell migration, polarity, and morphogenesis, 松本真司,岡本哲治,菊池章, 組織培養研究, Vol. 28, No. 2/3/4, 2009
  • Wnt5aにより活性化されるシグナルネットワークと消化管の発生分化の分子機構およびその異常による消化器癌の悪性化, 菊池章, 上原記念生命科学財団研究報告集(CD-ROM), Vol. 23, 2009
  • Wntによるβカテニン非依存性経路の活性化とその異常による病態, 菊池章,山本英樹,佐藤朗, 蛋白質 核酸 酵素, Vol. 54, No. 1, p. 1-10, 2009/01/01
  • Activation of the β-catenin-independent pathway by Wnt and the diseases due to its abnormality, 菊池 章,山本 英樹,佐藤 朗, Protein, nucleic acid and enzyme, 共立出版, Vol. 54, No. 1, p. 1-10, 2009/01
  • 三次元培養系を用いたWntシグナルによる上皮細胞の極性・形態形成制御機構についての解析, 松本真司,岡本哲治,菊池章, 日本口腔科学会雑誌, Vol. 57, No. 4, 2008/09/10
  • Wnt‐5aによるTGF‐β依存性軟骨細胞分化の制御, 中村光宏,安達伸生,出家正隆,越智光夫,菊池章, 日本整形外科学会雑誌, Vol. 82, No. 8, 2008/08/25
  • Wnt5a発現による胃癌の高度悪性化, 山本英喜,菊池章, 日本臨床, Vol. 66, p. 143-147, 2008/07/28
  • 三次元培養系を用いたWntシグナルによる上皮細胞の極性・形態形成制御機構についての解析, 松本真司,岡本哲治,菊池章, 組織培養研究, Vol. 27, No. 1, 2008/03/31
  • Wntシグナルによる細胞運動制御とその異常による癌の悪性化, 菊池章, 生化学, 2008
  • コンディショナルノックアウトマウスによるマウスWnt5aの機能解析, 小山浩史,佐藤朗,本田浩章,菊池章, 生化学, 2008
  • Wnt5aによるWnt3a‐β‐catenin経路の新規抑制機構の解析, 佐藤朗,坂根洋,小山浩史,菊池章, 生化学, 2008
  • DKK1によるLRP6のエンドサイトーシスを介するWntシグナル伝達の制御, 坂根洋,山本英樹,菊池章, 生化学, 2008
  • シグナル伝達 タンパク質間相互作用を介するWntシグナルの制御機構, 菊池章, 生体の科学, Vol. 58, No. 5, p. 404-406, 2007/10/15
  • タンパク質間相互作用を介するWntシグナルの制御機構 (タンパク質間相互作用), Vol. 58, No. 5, p. 404-406, 2007/09
  • Wnt‐5aによるTGF‐β依存性軟骨細胞分化の制御, 中村光宏,安達伸生,出家正隆,越智光夫,菊池章, 日本整形外科学会雑誌, Vol. 81, No. 8, 2007/08/25
  • Regulation of Wnt signalling by receptor-mediated endocytosis, Akira Kikuchi,Hideki Yamamoto, JOURNAL OF BIOCHEMISTRY, JAPANESE BIOCHEMICAL SOC, Vol. 141, No. 4, p. 443-451, 2007/04
  • SUMOとの結合を介する脱SUMO化酵素活性の制御, 小山浩史,井原基公,庄嶋健作,菊池章, 生化学, 2007
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  • Wnt‐5aは接着斑ダイナミクスを制御することにより胃癌細胞における細胞運動を促進する, 倉吉学,大上直秀,山本英樹,岸田想子,安井弥,菊池章, 日本癌学会学術総会記事, Vol. 65th, 2006/08/28
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  • 遺伝子機能からみた臓器特異的ヒト発がん Wntシグナル伝達経路におけるβ‐カテニンの機能制御とその異常による発がん, 菊池章,岸田昭世,山本英樹,日野真一郎, 日本癌学会総会記事, Vol. 62nd, 2003/08/25
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  • ヒト腎細胞におけるWnt及びPKAによるβ‐カテニンの蓄積及びその生理学的意義, 丹治知恵,山本英樹,頼岡徳在,河野修興,菊池章, 日本腎臓学会誌, Vol. 45, No. 3, 2003/04/25
  • Casein kinase I epsilon enhances the binding of Dvl-1 to Frat-1 and is essential for Wnt-3a-induced accumulation of beta-catenin, S Hino,T Michiue,M Asashima,A Kikuchi, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 278, No. 16, p. 14066-14073, 2003/04
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  • Tumor formation by genetic mutations in the components of the Wnt signaling pathway, Akira Kikuchi, Cancer Science, Vol. 94, No. 3, p. 225-229, 2003/03/01
  • Yeast glycogen synthase kinase-3 activates Msn2p-dependent transcription of stress responsive genes, Y Hirata,T Andoh,T Asahara,A Kikuchi, MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Vol. 14, No. 1, p. 302-312, 2003/01
  • Sumoylation is involved in b-catenin-dependent activation of Tcf-4., Vol. 22, No. 9, p. 2047-2059, 2003
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  • Sumoylation is involved in b-catenin-dependent activation of Tcf-4., EMBO J., Vol. 22, No. 9, p. 2047-2059, 2003
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  • Interaction of POB1, a downstream molecule of small G protein Ral, with PAG2, a paxillin-binding protein, is involved in cell migration, T Oshiro,S Koyama,S Sugiyama,A Kondo,Y Onodera,T Asahara,H Sabe,A Kikuchi, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 277, No. 41, p. 38618-38626, 2002/10
  • A-kinase anchoring protein AKAP220 binds to glycogen synthase kinase-3 beta (GSK-3 beta) and mediates protein kinase A-dependent inhibition of GSK-3 beta, C Tanji,H Yamamoto,N Yorioka,N Kohno,K Kikuchi,A Kikuchi, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 277, No. 40, p. 36955-36961, 2002/10
  • Interaction of POB1, a downstream molecule of small G protein Ral, with PAG2, a paxillin-binding protein, is involved in cell migration, T Oshiro,S Koyama,S Sugiyama,A Kondo,Y Onodera,T Asahara,H Sabe,A Kikuchi, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 277, No. 41, p. 38618-38626, 2002/10
  • A-kinase anchoring protein AKAP220 binds to glycogen synthase kinase-3 beta (GSK-3 beta) and mediates protein kinase A-dependent inhibition of GSK-3 beta, C Tanji,H Yamamoto,N Yorioka,N Kohno,K Kikuchi,A Kikuchi, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 277, No. 40, p. 36955-36961, 2002/10
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  • 低分子量G蛋白質Ralの下流分子であるPOB1は,パキシリン結合蛋白質PAG2と結合し,細胞運動を制御する, 大城 望史,小山 眞也,杉山 真一郎,佐邊 壽孝,菊池 章, 生化学, (公社)日本生化学会, Vol. 74, No. 8, p. 1049-1049, 2002/08
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  • Desumoylation activity of Axam, a novel Axin-binding protein, is involved in downregulation of beta-catenin, T Kadoya,H Yamamoto,T Suzuki,A Yukita,A Fukui,T Michiue,T Asahara,K Tanaka,M Asashima,A Kikuchi, MOLECULAR AND CELLULAR BIOLOGY, AMER SOC MICROBIOLOGY, Vol. 22, No. 11, p. 3803-3819, 2002/06
  • Desumoylation activity of Axam, a novel Axin-binding protein, is involved in downregulation of beta-catenin, T Kadoya,H Yamamoto,T Suzuki,A Yukita,A Fukui,T Michiue,T Asahara,K Tanaka,M Asashima,A Kikuchi, MOLECULAR AND CELLULAR BIOLOGY, AMER SOC MICROBIOLOGY, Vol. 22, No. 11, p. 3803-3819, 2002/06
  • Regulation of Wnt Signaling Pathway by Post-translational Modification., 角舎学行,菊池章, 細胞工学, Vol. 21, No. 6, p. 608-612, 2002/06
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  • Regulation of endocytosis of activin type II receptors by a novel PDZ protein through Ral/Ral-binding protein 1-dependent pathway, T Matsuzaki,S Hanai,H Kishi,ZH Liu,YL Bao,A Kikuchi,K Tsuchida,F Sugino, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 277, No. 21, p. 19008-19018, 2002/05
  • Regulation of endocytosis of activin type II receptors by a novel PDZ protein through Ral/Ral-binding protein 1-dependent pathway, T Matsuzaki,S Hanai,H Kishi,ZH Liu,YL Bao,A Kikuchi,K Tsuchida,F Sugino, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 277, No. 21, p. 19008-19018, 2002/05
  • Nuclear localization of Duplin, a beta-catenin-binding protein, is essential for its inhibitory activity on the Wnt signaling pathway, M Kobayashi,S Kishida,A Fukui,T Michiue,Y Miyamoto,T Okamoto,Y Yoneda,M Asashima,A Kikuchi, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 277, No. 8, p. 5816-5822, 2002/02
  • Nuclear localization of Duplin, a beta-catenin-binding protein, is essential for its inhibitory activity on the Wnt signaling pathway, M Kobayashi,S Kishida,A Fukui,T Michiue,Y Miyamoto,T Okamoto,Y Yoneda,M Asashima,A Kikuchi, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 277, No. 8, p. 5816-5822, 2002/02
  • ここまで分かった形づくりのシグナル伝達 細胞極性・細胞運動制御から情報伝達破綻による疾病まで 第3章 発生・分化・形態形成に関わるシグナリング 4 形態形成におけるWntシグナル伝達経路の役割, 小林雅史,岸田昭世,菊池章, 実験医学, Vol. 20, No. 2, p. 322-328, 2002/01/25
  • 細胞増殖におけるβ-カテニンの制御機構, Vol. 6, p. 22-25, 2002/01
  • 発生学から再生医療へ I 発生学の進歩 Wntシグナルによる背腹軸形成の分子機構, 大下彰彦,岸田昭世,菊池章, 医学のあゆみ, Vol. 199, No. 13, p. 907-912, 2001/12/29
  • DvlとカゼインキナーゼIεの相乗作用によるWntシグナルの制御, 日野真一郎,岸田想子,山本英樹,岸田昭世,菊池章, 日本癌学会総会記事, Vol. 60th, 2001/09/26
  • Protein Phosphatase 2Aの調節サブユニットPR61によるWntシグナル伝達経路の抑制, 山本英樹,桧井俊英,岸田昭世,菊池章, 日本癌学会総会記事, Vol. 60th, 2001/09/26
  • Synergistic Activation of the Wnt Signaling Pathway by Dvl and Casein Kinase Iε, Michiko Kishida,Shin-Ichiro Hino,Tatsuo Michiue,Hideki Yamamoto,Shosei Kishida,Akimasa Fukui,Makoto Asashima,Akira Kikuchi, Journal of Biological Chemistry, Vol. 276, No. 35, p. 33147-33155, 2001/08/31
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  • Inhibitory effect of a presenilin 1 mutation on the Wnt signalling pathway by enhancement of beta-catenin phosphorylation, Y Kawamura,A Kikuchi,R Takada,S Takada,S Sudoh,S Shibamoto,K Yanagisawa,H Komano, EUROPEAN JOURNAL OF BIOCHEMISTRY, BLACKWELL SCIENCE LTD, Vol. 268, No. 10, p. 3036-3041, 2001/05
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  • Wntシグナル伝達経路の異常と悪性腫よう 新規癌抑制遺伝子Axinを中心に, 池田聡,児玉真也,清水洋祐,藤森正彦,恵木浩之,岡島正純,岸田昭世,菊池章,浅原利正, 日本外科学会雑誌, Vol. 102, 2001/03/10
  • Role of the ENTH domain in phosphatidylinositol-4,5-bisphosphate binding and endocytosis, T Itoh,S Koshiba,T Kigawa,A Kikuchi,S Yokoyama,T Takenawa, SCIENCE, AMER ASSOC ADVANCEMENT SCIENCE, Vol. 291, No. 5506, p. 1047-1051, 2001/02
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  • Ras interaction with RalGDS effector targets, S Koyama,A Kikuchi, REGULATORS AND EFFECTORS OF SMALL GTPASES, PT F, RAS FAMILY I, ACADEMIC PRESS INC, Vol. 332, p. 127-138, 2001
  • Chondrocyte-derived ezrin-like domain containing protein (CDEP), a rho guanine nucleotide exchange factor, is inducible in chondrocytes by parathyroid hormone and cyclic AMP and has transforming activity in NIH3T3 cells., 2001
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  • b-arrestin1 modulates lymphoid enhnacer factor transcriptional activity through interaction with phosphorylated dishevelled proteins., Vol. 98, No. 26, p. 14889-14894, 2001
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  • Chondrocyte-derived ezrin-like domain containing protein (CDEP), a rho guanine nucleotide exchange factor, is inducible in chondrocytes by parathyroid hormone and cyclic AMP and has transforming activity in NIH3T3 cells., Ostoarthritis and Cartilage, 2001
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  • b-arrestin1 modulates lymphoid enhnacer factor transcriptional activity through interaction with phosphorylated dishevelled proteins., Proc. Natl. Acad. Sci. USA, Vol. 98, No. 26, p. 14889-14894, 2001
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  • Myosin II regulatory light chain as a novel substrate for AIM-1, an Aurora/Ipl1p-related kinase from rat, M Murata-Hori,K Fumoto,Y Fukuta,T Iwasaki,A Kikuchi,M Tatsuka,H Hosoya, JOURNAL OF BIOCHEMISTRY, JAPANESE BIOCHEMICAL SOC, Vol. 128, No. 6, p. 903-907, 2000/12
  • TGF‐βシグナルとWntシグナルのクロストーク‐TGF‐βシグナルに対するAxinの作用について, 古橋正男,八木健,島田真路,山本英樹,菊池章,加藤光保,宮園浩平, 日本分子生物学会年会プログラム・講演要旨集, Vol. 23rd, 2000/11/25
  • Wntシグナル伝達経路におけるβ‐カテニンのリン酸化の制御機構, 菊池章,岸田昭世,岸田想子,山本英樹, 日本分子生物学会年会プログラム・講演要旨集, Vol. 23rd, 2000/11/25
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  • GSK-3 b-dependent phosphorylation of adenomatous polyposis coli gene product can be modulated by b-catenin and protein phosphatase 2A complexed with Axin., Oncogene, p. 308-318, 2000
  • Complex Formation of Adenomatous Polyposis Coli Gene Product and Axin Facilitates GSK-3 b-dependent Phosphorylation of b-Catenin and Downregulates b-Catenin., J. Biol. Chem., Vol. 275, No. 44, p. 34399-34406, 2000
  • A novel b-catenin binding protein inhibits b-catenin-dependent Tcf activation and axis formation., J. Biol. Chem., Vol. 275, No. 42, p. 32871-32878, 2000
  • Regulation of Complex Formation of POB1/Epsin/Adaptor Complex 2 by Mitotic Phosphorylation., J. Biol. Chem., Vol. 275, No. 24, p. 18399-18406, 2000
  • Inhibition of Wnt Signaling Pathway by a Novel Axin-binding Protein, J. Biol. Chem., Vol. 275, No. 47, p. 37030-37037, 2000
  • Complex Formation of Adenomatous Polyposis Coli Gene Product and Axin Facilitates Glycogen Synthase kinase-3β-dependent Phosphorylation of β-Catein and Down-regulates β-Catenin, J. Biol. Chem., Vol. 275, No. 44, p. 34399-34406, 2000
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  • Ectopic expression of constitutively activated Ral GTPase inhibits cell shape changes during Drosophila eye development, K Sawamoto,C Yamada,S Kishida,Y Hirota,A Taguchi,A Kikuchi,H Okano, ONCOGENE, STOCKTON PRESS, Vol. 18, No. 11, p. 1967-1974, 1999/03
  • Ectopic expression of constitutively activated Ral GTPase inhibits cell shape changes during Drosophila eye development, K Sawamoto,C Yamada,S Kishida,Y Hirota,A Taguchi,A Kikuchi,H Okano, ONCOGENE, STOCKTON PRESS, Vol. 18, No. 11, p. 1967-1974, 1999/03
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  • Phosphorylation of Axin, a Wnt signal negative regulator, by glycogen synthase kinase-3b regulates its stability., Vol. 274, No. 16, p. 10681-10684, 1999
  • The Drosophila Ral GTPase regulates developmental cell shape changes through the Jun NH2-terminal kinase pathway., Vol. 146, No. 2, p. 361-372, 1999
  • DIX domains of Dvl and Axin are necessary for protein interactions and their ability to regulate b-catenin stability., p. 4414-4422, 1999
  • An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of b-catenin., Vol. 18, No. 9, p. 2401-2410, 1999
  • Small G protein Ral and its downstream molecules regulate endocytosis of EGF and insulin receptors., Vol. 18, No. 13, p. 3629-3642, 1999
  • The Drosophila Ral GTPare regulates Developmental Cell Shape Changes through the Jun NH<SUB>2</SUB>-terminal Kinase pathway, Vol. 146, No. 2, p. 361-372, 1999
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  • Axin prevents Wnt-3a-induced accumulation of b-catenin., Oncogene, Vol. 18, No. 4, p. 979-985, 1999
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  • Axin directly interacts with plakoglobin and regulates its stability., J. Biol. Chem., Vol. 274, No. 39, p. 27682-27688, 1999
  • Cdc42 and Rac1 Regulate the Interaction of IQGAP1 with b -catenin., J. Biol. Chem., Vol. 274, No. 37, p. 26044-26050, 1999
  • Phosphorylation of Axin, a Wnt signal negative regulator, by glycogen synthase kinase-3b regulates its stability., J. Biol. Chem., Vol. 274, No. 16, p. 10681-10684, 1999
  • The Drosophila Ral GTPase regulates developmental cell shape changes through the Jun NH2-terminal kinase pathway., J. Cell Biol., Vol. 146, No. 2, p. 361-372, 1999
  • DIX domains of Dvl and Axin are necessary for protein interactions and their ability to regulate b-catenin stability., Mol. Cell. Biol., p. 4414-4422, 1999
  • An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of b-catenin., EMBO J., Vol. 18, No. 9, p. 2401-2410, 1999
  • Small G protein Ral and its downstream molecules regulate endocytosis of EGF and insulin receptors., EMBO J., Vol. 18, No. 13, p. 3629-3642, 1999
  • The Drosophila Ral GTPare regulates Developmental Cell Shape Changes through the Jun NH<SUB>2</SUB>-terminal Kinase pathway, J. Cell Biol., Vol. 146, No. 2, p. 361-372, 1999
  • Small G protein Ral and its downstream malecules regulate endocytosis of EGF and insulin receptors, EMBO J., Vol. 18, No. 13, p. 3629-3642, 1999
  • Axin directly interacts with plakoglobin and regulates its stability, J. Biol. Chem., Vol. 274, No. 39, p. 27682-27688, 1999
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  • A role of Axin, a negative regulator of the Wnt signaling pathway, in axis formation., 菊池章, 実験医学, Vol. 16, No. 17, p. 2173-2179, 1998/11
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  • Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3β and β-catenin and promotes GSK-3β-dependent phosphorylation of β-catenin, Satoshi Ikeda,Shosei Kishida,Hideki Yamamoto,Hiroshi Murai,Shinya Koyama,Akira Kikuchi, EMBO Journal, Vol. 17, No. 5, p. 1371-1384, 1998/03/02
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  • Identification and characterization of a novel protein interacting with Ral-binding protein 1, a putative effector protein of Ral., Vol. 273, No. 2, p. 814-821, 1998
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  • Axin, a negative regulator of the Wnt signaling pathway, directly interacts with adenomatous polyposis coli and regulates the stabilization of β-catenin, Vol. 273, No. 18, p. 10823-10826, 1998
  • Axil, a member of the Axin family, interacts with both glycogen synthase kinase 3β and β-catenin and inhibits axis formation of Xenopus embryos., Vol. 18, No. 5, 1998
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  • Identification and characterization of a novel protein interacting with Ral-binding protein 1, a putative effector protein of Ral., J. Biol. Chem., Vol. 273, No. 2, p. 814-821, 1998
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  • Axil, a member of the Axin family, interacts with both glycogen synthase kinase 3b and b-catenin and inhibits axis formation of Xenopus embryos., Mol. Cell. Biol., p. 2867-2875, 1998
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  • Axil, a member of the Axin family, interacts with both glycogen synthase kinase 3β and β-catenin and inhibits axis formation of Xenopus embryos., Mol. Cell. Biol., Vol. 18, No. 5, 1998
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  • Regulation of cross-linking of actin filament by IQGAP1, a target for Cdc42., J. Biol. Chem., Vol. 272, No. 47, p. 29579-29583, 1997
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  • Progress in Endocrinology, 1988
  • Phosphorylation by cyclic AMP-dependent protein kinase of a human platelet Mr 22,000 GTP-binding protein (smg p21) having the same putative effector domain as the ras gene products., Vol. 157, No. 3, p. 851-860, 1988
  • Identification of a platelet Mr 22,000 GTP-binding protein as the novel smg-21 gene product having the same putative effector domain as the ras gene products., Vol. 157, No. 2, p. 670-676, 1988
  • Small molecular weight GTP-binding proteins in human erythrocyte ghosts., Vol. 156, No. 2, p. 889-897, 1988
  • Multiple small molecular weight GTP-binding proteins in bovine brain cytosol Purification and characterization of a 24KDa protein., Vol. 155, No. 3, p. 1284-1292, 1988
  • Purification and characterization of c-Ki-ras p21 from bovine brain crude membranes., p. 17181-17188, 1988
  • ADP-ribosylation of the bovine brain rho protein by botulinum toxin type C1., p. 16303-16308, 1988
  • Nucleotide and deduced amino acid sequences of a GTP-binding protein family with molecular weights of 25,000 from bovine brain., p. 11071-11074, 1988
  • Purification and characterization of a novel GTP-binding protein with a molecular weight of 24,000 from bovine brain membranes., p. 2897-2904, 1988
  • Progress in Endocrinology, Elsevier Science Publishers, 1988
  • Phosphorylation by cyclic AMP-dependent protein kinase of a human platelet Mr 22,000 GTP-binding protein (smg p21) having the same putative effector domain as the ras gene products., Biochem. Biophys. Res. Commun., Vol. 157, No. 3, p. 851-860, 1988
  • Identification of a platelet Mr 22,000 GTP-binding protein as the novel smg-21 gene product having the same putative effector domain as the ras gene products., Biochem. Biophys. Res. Commun., Vol. 157, No. 2, p. 670-676, 1988
  • Small molecular weight GTP-binding proteins in human erythrocyte ghosts., Biochem. Biophys. Res. Commun., Vol. 156, No. 2, p. 889-897, 1988
  • Multiple small molecular weight GTP-binding proteins in bovine brain cytosol Purification and characterization of a 24KDa protein., Biochem. Biophys. Res. Commun., Vol. 155, No. 3, p. 1284-1292, 1988
  • Purification and characterization of c-Ki-ras p21 from bovine brain crude membranes., J. Biol. Chem., p. 17181-17188, 1988
  • ADP-ribosylation of the bovine brain rho protein by botulinum toxin type C1., J. Biol. Chem., p. 16303-16308, 1988
  • Nucleotide and deduced amino acid sequences of a GTP-binding protein family with molecular weights of 25,000 from bovine brain., J. Biol. Chem., p. 11071-11074, 1988
  • Purification and characterization of a novel GTP-binding protein with a molecular weight of 24,000 from bovine brain membranes., J. Biol. Chem., p. 2897-2904, 1988
  • Modes of inhibitory action of protein kinase C in the chemotactic peptide-induced formation of inositol phosphates in differentiated human leukemic (HL-60) cells., p. 6766-6770, 1987
  • Modes of inhibitory action of protein kinase C in the chemotactic peptide-induced formation of inositol phosphates in differentiated human leukemic (HL-60) cells., J. Biol. Chem., p. 6766-6770, 1987
  • INVOLVEMENT OF A GUANINE NUCLEOTIDE-BINDING PROTEIN IN COUPLING OF RECEPTORS TO PHOSPHOLIPASE C-MEDIATED PHOSPHOINOSITIDE HYDROLYSIS, Y TAKAI,A KIKUCHI,O KOZAWA, CELL STRUCTURE AND FUNCTION, JAPAN SOC CELL BIOLOGY, Vol. 11, No. 4, p. 396-396, 1986/12
  • INHIBITION OF CHEMOTACTIC PEPTIDE-INDUCED PHOSPHOINOSITIDE HYDROLYSIS BY PHORBOL ESTERS THROUGH THE ACTIVATION OF PROTEIN-KINASE-C IN DIFFERENTIATED HUMAN-LEUKEMIA (HL-60) CELLS, A KIKUCHI,O KOZAWA,Y HAMAMORI,K KAIBUCHI,Y TAKAI, CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Vol. 46, No. 7, p. 3401-3406, 1986/07
  • INHIBITION OF CHEMOTACTIC PEPTIDE-INDUCED PHOSPHOINOSITIDE HYDROLYSIS BY PHORBOL ESTERS THROUGH THE ACTIVATION OF PROTEIN-KINASE-C IN DIFFERENTIATED HUMAN-LEUKEMIA (HL-60) CELLS, A KIKUCHI,O KOZAWA,Y HAMAMORI,K KAIBUCHI,Y TAKAI, CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Vol. 46, No. 7, p. 3401-3406, 1986/07
  • FORMATION OF A PHORBOL ESTER-BINDING FRAGMENT FROM PROTEIN-KINASE-C BY PROTEOLYTIC DIGESTION, M HOSHIJIMA,A KIKUCHI,T TANIMOTO,K KAIBUCHI,Y TAKAI, CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Vol. 46, No. 6, p. 3000-3004, 1986/06
  • FORMATION OF A PHORBOL ESTER-BINDING FRAGMENT FROM PROTEIN-KINASE-C BY PROTEOLYTIC DIGESTION, M HOSHIJIMA,A KIKUCHI,T TANIMOTO,K KAIBUCHI,Y TAKAI, CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Vol. 46, No. 6, p. 3000-3004, 1986/06
  • Gunma Symposia on Endocrinology: Molecular Mechanism of Biosignal Transduction, 1986
  • Direct evidence for involvement of a guanine nucleotide-binding protein in chemotactic peptide-stimulated formation of inositol bisphosphate and trisphosphate in differentiated human leukemic (HL-60) cells Reconstitution with Gi or Go of the plasma mem・・・, p. 11558-11562, 1986
  • Possible involvement of protein kinase C and calcium ion in growth factor-induced expression of c-myc oncogene in Swiss 3T3 fibroblasts., p. 1187-1192, 1986
  • Gunma Symposia on Endocrinology: Molecular Mechanism of Biosignal Transduction, Center for Academic Publications Japan, 1986
  • Direct evidence for involvement of a guanine nucleotide-binding protein in chemotactic peptide-stimulated formation of inositol bisphosphate and trisphosphate in differentiated human leukemic (HL-60) cells Reconstitution with Gi or Go of the plasma mem・・・, J. Biol. Chem., p. 11558-11562, 1986
  • Possible involvement of protein kinase C and calcium ion in growth factor-induced expression of c-myc oncogene in Swiss 3T3 fibroblasts., J. Biol. Chem., p. 1187-1192, 1986
  • ENHANCEMENT OF COLLAGEN-INDUCED PHOSPHOINOSITIDE TURNOVER BY THROMBOXANE-A2 ANALOG THROUGH CA-2+ MOBILIZATION IN HUMAN-PLATELETS, K KAIBUCHI,T TSUDA,A KIKUCHI,T TANIMOTO,Y TAKAI, FEBS LETTERS, ELSEVIER SCIENCE BV, Vol. 192, No. 1, p. 104-108, 1985
  • ENHANCEMENT OF COLLAGEN-INDUCED PHOSPHOINOSITIDE TURNOVER BY THROMBOXANE-A2 ANALOG THROUGH CA-2+ MOBILIZATION IN HUMAN-PLATELETS, K KAIBUCHI,T TSUDA,A KIKUCHI,T TANIMOTO,Y TAKAI, FEBS LETTERS, ELSEVIER SCIENCE BV, Vol. 192, No. 1, p. 104-108, 1985
  • ISOLATION AND PROPERTIES OF CASEIN KINASES FROM HUMAN-PLATELETS, A KIKUCHI,S TOMISAKA,K YONEZAWA,A SANO,H YAMAMURA, BIOMEDICAL RESEARCH-TOKYO, BIOMED RES FOUND, Vol. 3, No. 5, p. 477-481, 1982
  • ISOLATION AND PROPERTIES OF CASEIN KINASES FROM HUMAN-PLATELETS, A KIKUCHI,S TOMISAKA,K YONEZAWA,A SANO,H YAMAMURA, BIOMEDICAL RESEARCH-TOKYO, BIOMED RES FOUND, Vol. 3, No. 5, p. 477-481, 1982

Publications

  • 細胞, 先端医学社, 2001
  • 遺伝子医学, メディカルドウ, 2001
  • 実験医学, 羊土社, 2000
  • 細胞工学, 秀潤社, 2000
  • シグナル伝達ネットワーク, 東京化学同人, 2000
  • 分子細胞治療, 先端医学社, 2000
  • Molecular Medicine, 中山書店, 2000
  • Molecular Medicine, 2000
  • 別冊・医学のあゆみ 神経疾患, 医歯薬出版, 1999
  • G.I. Research, 先端医学社, 1999
  • G.I. Research, 1999
  • 神経伝達物質update, 中外医学社, 1998
  • 実験医学, 羊土社, 1998
  • 実験医学, 羊土社, 1998
  • 実験医学, 羊土社, 1996
  • 生化学, 日本生化学会, 1996
  • 実験医学, 羊土社, 1994
  • 生化学, 日本生化学会, 1992
  • 実験医学, 羊土社, 1992
  • リピドバイオファクター, 化学同人, 1992
  • 皮膚科紀要, 日本皮膚科学会, 1991
  • 実験医学, 羊土社, 1991
  • 細胞科学, 1991
  • 日本内分泌学会誌, 日本内分泌学会, 1991
  • 実験医学, 羊土社, 1990
  • 実験医学, 羊土社, 1990
  • 実験医学, 羊土社, 1990
  • 実験医学, 羊土社, 1990
  • 病態代謝, 病態代謝研究会, 1990
  • 実験医学, 羊土社, 1989
  • 神経研究の進歩, 1989
  • 病態生理, 1989
  • 癌と化学療法, 1989
  • セラピテック・リサーチ, 1988
  • 医学のあゆみ, 医歯薬出版, 1988
  • 蛋白質核酸酵素, 共立出版社, 1988
  • 実験医学, 羊土社, 1988
  • 実験医学, 羊土社, 1988
  • 癌と化学療法, 1986
  • 代謝 免疫 85, 中山書店, 1985

Industrial Property Rights

  • 抗CKAP4モノクローナル抗体, PCT/JP2018/035719, PCT/JP2018/035719, PCT/JP2018/035719, 出願日:2017/09
  • CKAP4を標的とした抗腫瘍剤, 2017090701503100(CN), 2017090701503100(CN), 2017090701503100(CN), 出願日:2017/09
  • CKAP4を標的とした抗腫瘍剤, 16755122.5 (EP), 16755122.5 (EP), 16755122.5 (EP), 出願日:2017/09
  • CKAP4を標的とした抗腫瘍剤, 15/553941 (US), 15/553941 (US), 15/553941 (US), 出願日:2017/08
  • CKAP4を標的分子とした抗腫瘍剤, 特願2018-059655, 出願日:2018/03/27
  • CKAP4を標的分子とした抗腫瘍剤, JP2016052485, 出願日:2016/01/28
  • 癌治療用医薬組成物, 特願2014-190619, 出願日:2014/09/19
  • CKAP4を標的分子とした抗腫瘍剤, 特許第6316498号, 特願2017-501998, 出願日:2016/01/28

Works

  • 細胞におけるシグナル系の役割の検討 第一製薬(株), -
  • がん遺伝子産物Rasと関連する分子を用いた新しいがんの遺伝子診断キットの開発 広島県産業技術振興機構地域研究開発促進拠点支援事業, -

Awards

  • 日本生化学会奨励賞, 1991
  • 生化学会奨励賞, 1991