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Clement Angkawidjaja
アンカウィジャヤ クレメン
Clement Angkawidjaja
アンカウィジャヤ クレメン
Center for Student Success Research and Practice,Associate Professor

Research History 8

  1. 2025/08 - Present
    The University of Osaka Global Health Initiatives, Graduate School of Medicine and The Osaka University Hospital Associate Professor

  2. 2025/04 - Present
    The University of Osaka Career Center Associate Professor

  3. 2024/08 - Present
    Osaka University Center for Student Success Research and Practice Associate Professor

  4. 2020/04 - 2024/07
    Osaka University Center for Global Initiatives Specially Appointed Associate Professor (Lecturer)

  5. 2017/07 - 2020/03
    Osaka University Administration Bureau International college Specially Appointed Associate Professor (Lecturer)

  6. 2016/01 - 2017/06
    Evec, Inc. Sapporo Laboratory Researcher

  7. 2010/05 - 2015/12
    Osaka University Administration Bureau International college Specially Appointed Assistant Professor

  8. 2007/10 - 2010/04
    Osaka University Graduate School of Engineering Specially Appointed Assistant Professor

Research Areas 3

  1. Humanities & social sciences / Education - general / International education

  2. Humanities & social sciences / Education - general / Career education

  3. Life sciences / Structural biochemistry /

Papers 39

  1. Affinity shift of ATP upon glycerol binding to a glycerol kinase from the hyperthermophilic archaeon Thermococcus kodakarensis KOD1

    Hokao Ryuta, Matsumura Hiroyoshi, Katsumi Ryota, Angkawidjaja Clement, Takano Kazufumi, Kanaya Shigenori, Koga Yuichi

    Journal of bioscience and bioengineering Vol. 129 No. 6 p. 657-663 2020/06

    Publisher: Society for Biotechnology
  2. Crystal structure of the Fab region of a neutralizing antibody against granulocyte-macrophage colony-stimulating factor.

    Clement Angkawidjaja, Takashi Torashima

    Acta crystallographica. Section F, Structural biology communications Vol. 75 No. Pt 10 p. 634-639 2019/10/01 Research paper (scientific journal)

  3. Structural Basis for the Serratia marcescens Lipase Secretion System: Crystal Structures of the Membrane Fusion Protein and Nucleotide-Binding Domain.

    Daichi Murata, Hiroyuki Okano, Clement Angkawidjaja, Masato Akutsu, Shun-Ichi Tanaka, Kenyu Kitahara, Takuya Yoshizawa, Hiroyoshi Matsumura, Yuji Kado, Eiichi Mizohata, Tsuyoshi Inoue, Satoshi Sano, Yuichi Koga, Shigenori Kanaya, Kazufumi Takano

    Biochemistry Vol. 56 No. 47 p. 6281-6291 2017/11/28 Research paper (scientific journal)

  4. Hydrophobic interactions induced activation of a thermo-alkalophilic lipase from Geobacillus SBS-4S by molecular dynamics simulations

    Muhammad Tayyab, Naeem Rashid, Clement Angkawidjaja, Shigenori Kanaya, Muhammad Wasim, Ali Raza Awan, Sehrish Firyal, Tahir Yaqub, Masood Ahmed Siddiqui

    Journal of the Chemical Society of Pakistan Vol. 37 No. 5 p. 1030-1032 2015/10/01 Research paper (scientific journal)

    Publisher: Chemical Society of Pakistan
  5. Structure, activity, and stability of metagenome-derived glycoside hydrolase family 9 endoglucanase with an N-terminal Ig-like domain.

    Hiroyuki Okano, Eiko Kanaya, Masashi Ozaki, Clement Angkawidjaja, Shigenori Kanaya

    Protein science : a publication of the Protein Society Vol. 24 No. 3 p. 408-19 2015/03 Research paper (scientific journal)

  6. Structural and biochemical characterization of a metagenome-derived esterase with a long N-terminal extension.

    Hiroyuki Okano, Xun Hong, Eiko Kanaya, Clement Angkawidjaja, Shigenori Kanaya

    Protein science : a publication of the Protein Society Vol. 24 No. 1 p. 93-104 2015/01 Research paper (scientific journal)

  7. Rational design of a glycosynthase by the crystal structure of β-galactosidase from Bacillus circulans (BgaC) and its use for the synthesis of N-acetyllactosamine type 1 glycan structures.

    Manja Henze, Dong-Ju You, Claudia Kamerke, Natalie Hoffmann, Clement Angkawidjaja, Sabrina Ernst, Jörg Pietruszka, Shigenori Kanaya, Lothar Elling

    Journal of biotechnology Vol. 191 p. 78-85 2014/12/10 Research paper (scientific journal)

  8. Structural basis for salt-dependent folding of ribonuclease H1 from halophilic archaeon Halobacterium sp. NRC-1.

    Dong-Ju You, Nujarin Jongruja, Elias Tannous, Clement Angkawidjaja, Yuichi Koga, Shigenori Kanaya

    Journal of structural biology Vol. 187 No. 2 p. 119-128 2014/08 Research paper (scientific journal)

  9. Calcium-independent opening of lid1 of a family I.3 lipase by a single Asp to Arg mutation at the calcium-binding site.

    M Cheng, C Angkawidjaja, Y Koga, S Kanaya

    Protein engineering, design & selection : PEDS Vol. 27 No. 5 p. 169-76 2014/05 Research paper (scientific journal)

  10. Structural and mechanistic insights into the kynurenine aminotransferase-mediated excretion of kynurenic acid.

    Ken Okada, Clement Angkawidjaja, Yuichi Koga, Shigenori Kanaya

    Journal of structural biology Vol. 185 No. 3 p. 257-66 2014/03 Research paper (scientific journal)

  11. Structure and stability of metagenome-derived glycoside hydrolase family 12 cellulase (LC-CelA) a homolog of Cel12A from Rhodothermus marinus.

    Hiroyuki Okano, Masashi Ozaki, Eiko Kanaya, Joong-Jae Kim, Clement Angkawidjaja, Yuichi Koga, Shigenori Kanaya

    FEBS open bio Vol. 4 p. 936-46 2014 Research paper (scientific journal)

  12. Formation of the high-affinity calcium binding site in pro-subtilisin E with the insertion sequence IS1 of pro-Tk-subtilisin.

    Ryo Uehara, Clement Angkawidjaja, Yuichi Koga, Shigenori Kanaya

    Biochemistry Vol. 52 No. 50 p. 9080-8 2013/12/17 Research paper (scientific journal)

  13. Role of N-terminal extension of Bacillus stearothermophilus RNase H2 and C-terminal extension of Thermotoga maritima RNase H2.

    Etin-Diah Permanasari, Clement Angkawidjaja, Yuichi Koga, Shigenori Kanaya

    The FEBS journal Vol. 280 No. 20 p. 5065-79 2013/10 Research paper (scientific journal)

  14. Crystallization and X-ray structure determination of a thermoalkalophilic lipase from Geobacillus SBS-4S.

    Muhammad Tayyab, Naeem Rashid, Clement Angkawidjaja, Shigenori Kanaya, Muhammad Akhtar

    Acta crystallographica. Section F, Structural biology and crystallization communications Vol. 69 No. Pt 4 p. 355-7 2013/04/01 Research paper (scientific journal)

  15. Accelerated maturation of Tk-subtilisin by a Leu -> Promutation at the C-terminus of the propeptide, which reduces the binding of the propeptide to Tk-subtilisin

    Ryo Uehara, Yasunori Ueda, Dong-Ju You, Yuichi Koga, Shigenori Kanaya

    FEBS JOURNAL Vol. 280 No. 4 p. 994-1006 2013/02 Research paper (scientific journal)

  16. Requirement of lid2 for interfacial activation of a family I.3 lipase with unique two lid structures.

    Maria Cheng, Clement Angkawidjaja, Yuichi Koga, Shigenori Kanaya

    The FEBS journal Vol. 279 No. 19 p. 3727-3737 2012/10 Research paper (scientific journal)

  17. Structure and stability of a thermostable carboxylesterase from the thermoacidophilic archaeon Sulfolobus tokodaii.

    Clement Angkawidjaja, Yuichi Koga, Kazufumi Takano, Shigenori Kanaya

    The FEBS journal Vol. 279 No. 17 p. 3071-84 2012/09 Research paper (scientific journal)

  18. Structure and characterization of RNase H3 from Aquifex aeolicus.

    Nujarin Jongruja, Dong-Ju You, Clement Angkawidjaja, Eiko Kanaya, Yuichi Koga, Shigenori Kanaya

    The FEBS journal Vol. 279 No. 15 p. 2737-53 2012/08 Research paper (scientific journal)

  19. Activity, stability, and structure of metagenome-derived LC11-RNase H1, a homolog of Sulfolobus tokodaii RNase H1.

    Tri-Nhan Nguyen, Clement Angkawidjaja, Eiko Kanaya, Yuichi Koga, Kazufumi Takano, Shigenori Kanaya

    Protein science : a publication of the Protein Society Vol. 21 No. 4 p. 553-61 2012/04 Research paper (scientific journal)

  20. Role of polar and nonpolar residues at the active site for PPIase activity of FKBP22 from Shewanella sp. SIB1.

    Cahyo Budiman, Takashi Tadokoro, Clement Angkawidjaja, Yuichi Koga, Shigenori Kanaya

    The FEBS journal Vol. 279 No. 6 p. 976-86 2012/03 Research paper (scientific journal)

  21. Ca2+ regulates the Drosophila Stoned-A and Stoned-B proteins interaction with the C2B domain of Synaptotagmin-1.

    Carolina Soekmadji, Clement Angkawidjaja, Leonard E Kelly

    PloS one Vol. 7 No. 6 2012 Research paper (scientific journal)

  22. Characteristic features of kynurenine aminotransferase allosterically regulated by (alpha)-ketoglutarate in cooperation with kynurenine.

    Ken Okada, Clement Angkawidjaja, Yuichi Koga, Kazufumi Takano, Shigenori Kanaya

    PloS one Vol. 7 No. 7 2012 Research paper (scientific journal)

  23. Crystal structure of N-domain of FKBP22 from Shewanella sp. SIB1: dimer dissociation by disruption of Val-Leu knot.

    Cahyo Budiman, Clement Angkawidjaja, Hideki Motoike, Yuichi Koga, Kazufumi Takano, Shigenori Kanaya

    Protein science : a publication of the Protein Society Vol. 20 No. 10 p. 1755-64 2011/10 Research paper (scientific journal)

  24. Identification of the substrate binding site in the N-terminal TBP-like domain of RNase H3.

    Seiko Miyashita, Takashi Tadokoro, Clement Angkawidjaja, Dong-Ju You, Yuichi Koga, Kazufumi Takano, Shigenori Kanaya

    FEBS letters Vol. 585 No. 14 p. 2313-7 2011/07/21 Research paper (scientific journal)

  25. Importance of an extreme C-terminal motif of a family I.3 lipase for stability.

    K Kuwahara, C Angkawidjaja, Y Koga, K Takano, S Kanaya

    Protein engineering, design & selection : PEDS Vol. 24 No. 5 p. 411-8 2011/05 Research paper (scientific journal)

  26. Highly active metallocarboxypeptidase from newly isolated Geobacillus strain SBS-4S : Cloning and characterization

    TAYYAB Muhammad, RASHID Naeem, ANGKAWIDJAJA Clement, KANAYA Shigenori, AKHTAR Muhammad

    Journal of bioscience and bioengineering Vol. 111 No. 3 p. 259-265 2011/03/25

    Publisher: The Society for Biotechnology, Japan
  27. Stabilization by fusion to the C-terminus of hyperthermophile Sulfolobus tokodaii RNase HI: a possibility of protein stabilization tag.

    Kazufumi Takano, Tomohiro Okamoto, Jun Okada, Shun-ichi Tanaka, Clement Angkawidjaja, Yuichi Koga, Shigenori Kanaya

    PloS one Vol. 6 No. 1 2011/01/19 Research paper (scientific journal)

  28. Crystal structure of stable protein CutA1 from psychrotrophic bacterium Shewanella sp. SIB1.

    Aya Sato, Sonoko Yokotani, Takashi Tadokoro, Shun-ichi Tanaka, Clement Angkawidjaja, Yuichi Koga, Kazufumi Takano, Shigenori Kanaya

    Journal of synchrotron radiation Vol. 18 No. 1 p. 6-10 2011/01 Research paper (scientific journal)

  29. Protein core adaptability: crystal structures of the cavity-filling variants of Escherichia coli RNase HI.

    Masaki Tanaka, Hyongi Chon, Clement Angkawidjaja, Yuichi Koga, Kazufumi Takano, Shigenori Kanaya

    Protein and peptide letters Vol. 17 No. 9 p. 1163-9 2010/09 Research paper (scientific journal)

  30. Crystal structure of a subtilisin homologue, Tk-SP, from Thermococcus kodakaraensis: requirement of a C-terminal beta-jelly roll domain for hyperstability.

    Tita Foophow, Shun-ichi Tanaka, Clement Angkawidjaja, Yuichi Koga, Kazufumi Takano, Shigenori Kanaya

    Journal of molecular biology Vol. 400 No. 4 p. 865-77 2010/07/23 Research paper (scientific journal)

  31. X-ray crystallographic and MD simulation studies on the mechanism of interfacial activation of a family I.3 lipase with two lids.

    Clement Angkawidjaja, Hiroyoshi Matsumura, Yuichi Koga, Kazufumi Takano, Shigenori Kanaya

    Journal of molecular biology Vol. 400 No. 1 p. 82-95 2010/07/02 Research paper (scientific journal)

  32. Engineering of monomeric FK506-binding protein 22 with peptidyl prolyl cis-trans isomerase. Importance of a V-shaped dimeric structure for binding to protein substrate.

    Cahyo Budiman, Keisuke Bando, Clement Angkawidjaja, Yuichi Koga, Kazufumi Takano, Shigenori Kanaya

    The FEBS journal Vol. 276 No. 15 p. 4091-101 2009/08 Research paper (scientific journal)

  33. Destabilization of psychrotrophic RNase HI in a localized fashion as revealed by mutational and X-ray crystallographic analyses.

    Muhammad S Rohman, Takashi Tadokoro, Clement Angkawidjaja, Yumi Abe, Hiroyoshi Matsumura, Yuichi Koga, Kazufumi Takano, Shigenori Kanaya

    The FEBS journal Vol. 276 No. 2 p. 603-13 2009/01 Research paper (scientific journal)

  34. Importance of the Ca2+-binding sites in the N-catalytic domain of a family I.3 lipase for activity and stability.

    K Kuwahara, C Angkawidjaja, H Matsumura, Y Koga, K Takano, S Kanaya

    Protein engineering, design & selection : PEDS Vol. 21 No. 12 p. 737-44 2008/12 Research paper (scientific journal)

  35. Crystal structure of a family I.3 lipase from Pseudomonas sp. MIS38 in a closed conformation.

    Clement Angkawidjaja, Dong-ju You, Hiroyoshi Matsumura, Katsumasa Kuwahara, Yuichi Koga, Kazufumi Takano, Shigenori Kanaya

    FEBS letters Vol. 581 No. 26 p. 5060-4 2007/10/30 Research paper (scientific journal)

  36. Extracellular overproduction and preliminary crystallographic analysis of a family I.3 lipase.

    Clement Angkawidjaja, Dong-Ju You, Hiroyoshi Matsumura, Yuichi Koga, Kazufumi Takano, Shigenori Kanaya

    Acta crystallographica. Section F, Structural biology and crystallization communications Vol. 63 No. Pt 3 p. 187-9 2007/03/01 Research paper (scientific journal)

  37. Family I.3 lipase: bacterial lipases secreted by the type I secretion system.

    C Angkawidjaja, S Kanaya

    Cellular and molecular life sciences : CMLS Vol. 63 No. 23 p. 2804-17 2006/12 Research paper (scientific journal)

  38. Extracellular secretion of Escherichia coli alkaline phosphatase with a C-terminal tag by type I secretion system: purification and biochemical characterization.

    C Angkawidjaja, K Kuwahara, K Omori, Y Koga, K Takano, S Kanaya

    Protein engineering, design & selection : PEDS Vol. 19 No. 7 p. 337-43 2006/07 Research paper (scientific journal)

  39. Importance of a repetitive nine-residue sequence motif for intracellular stability and functional structure of a family I.3 lipase.

    Clement Angkawidjaja, Aditya Paul, Yuichi Koga, Kazufumi Takano, Shigenori Kanaya

    FEBS letters Vol. 579 No. 21 p. 4707-12 2005/08/29 Research paper (scientific journal)

Misc. 13

  1. Crystal Structure of Glycoside Hydrolase Family 9 Endoglucanase with an N-Terminal Ig-Like Domain Isolated from Leaf-Branch Compost

    Hiroyuki Okano, Eiko Kanaya, Masashi Ozaki, Clement Angkawidjaja, Yuichi Koga, Shigenori Kanaya

    BIOPHYSICAL JOURNAL Vol. 108 No. 2 p. 226A-226A 2015/01 Research paper, summary (international conference)

  2. Rational Design of a Family I.3 Lipase Possessing Calcium-independent Activities

    Maria Cheng, Clement Angkawidjaja, Yuichi Koga, Shigenori Kanaya

    PROTEIN SCIENCE Vol. 21 p. 80-81 2012/08 Research paper, summary (international conference)

  3. 2Cp12 Evolvability of thermophilic proteins from Archaea and Bacteria

    Aoi Atsushi, Angkawidjaja Clement, Koga Yuichi, Takano Kazufumi, Kanaya Shigenori

    Vol. 64 p. 41-41 2012

    Publisher: 日本生物工学会
  4. 2Cp14 Study of novel metagenome-derived esterase from leaf-and-branch compost

    Okano Hiroyuki, Hong Xun, Yamato Saya, Kanaya Eiko, You Dong-Ju, Angkawidjaja Clement, Koga Yuichi, Kanaya Shigenori

    Vol. 64 p. 42-42 2012

    Publisher: 日本生物工学会
  5. 2Cp21 Activity and Stability of an Artificial Protein with Two Tandemly-linked RNase H Molecules

    Takamiya Takashi, Kanaya Eiko, Angkawidjaja Clement, You Dong-Ju, Takano Kazufumi, Koga Yuichi, Kanaya Shigenori

    Vol. 64 p. 43-43 2012

    Publisher: 日本生物工学会
  6. 2Cp24 Analysis of molecular mechanism for enantioselectivity of lipase from Burkholderia cepacia KWI-56

    Hatanaka Akitomo, Fukuda Hiroyuki, You Dong-Ju, Angkawidjaja Clement, Koga Yuichi, Kanaya Shigenori

    Vol. 64 p. 44-44 2012

    Publisher: 日本生物工学会
  7. 4Cp18 Crystal structure of a metagenome-derived homolog of Sulfolobus tokodaii RNase H1 :

    Nguyen Tri-Nhan, Angkawidjaja Clement, Matsumoto Hiroyuki, You Dong-Ju, Koga Yuichi, Kanaya Shigenori

    Vol. 64 p. 199-199 2012

    Publisher: 日本生物工学会
  8. 2つの同一ドメインを分子内に持つ人工タンパク質の安定性と活性

    高宮 毅志, 金谷 栄子, Angkawidjaja Clement, 劉 東周, 古賀 雄一, 高野 和文, 金谷 茂則

    日本生化学会大会プログラム・講演要旨集 Vol. 84回 p. 2P-0170 2011/09

    Publisher: (公社)日本生化学会
  9. Thermococcus kodakaraensis由来のサブチリシン相同体であるTk-SPの安定性にCa2+イオンが果たす役割(Role of the Ca2+ ions for stability of subtilisin homologue, Tk-SP, from Thermococcus kadakaraensis)

    Nitat Sinsereekul, Foophow Tita, Angkawidjaja Clement, Koga Yuichi, Takano Kazufumi, Kanaya Shigenori

    日本生化学会大会プログラム・講演要旨集 Vol. 84回 p. 2P-0531 2011/09

    Publisher: (公社)日本生化学会
  10. LipBのATP結合ドメインの構造機能解析

    岡野 啓志, 中村 仁美, Angkawidjaja Clement, 古賀 雄一, 高野 和文, 金谷 茂則

    日本生化学会大会・日本分子生物学会年会合同大会講演要旨集 Vol. 83回・33回 p. 2P-0016 2010/12

    Publisher: (公社)日本生化学会
  11. Antioxidant and DNA Damage Prevention Activities of the Edible Parts of Gnetum gnemon and Their Changes upon Heat Treatment

    SANTOSO Martha, NAKA Yuko, ANGKAWIDJAJA Clement, YAMAGUCHI Tomoko, MATOBA Teruyoshi, TAKAMURA Hitoshi

    Food Science and Technology Research Vol. 16 No. 6 p. 549-556 2010/11/01

    Publisher: Japanese Society for Food Science and Technology
  12. Arg142とPhe197はシュワネラ種SIB1由来FKBP22のプロリルイソメラーゼ活性に重要である(Importance of Arg142 and Phe197 for Prolyl Isomerase Activity of FKBP22 from Shewanella sp. SIB1)

    ブディマン・チャヒヨ, 田所 高志, アンカウィジャヤ・クレメン, 古賀 雄一, 高野 和文, 金谷 茂則

    日本生化学会大会プログラム・講演要旨集 Vol. 82回 p. 2P-417 2009/09

    Publisher: (公社)日本生化学会
  13. 1P-020 Mechanism of Interfacial Activation of a Family I.3 Lipase with Two Lid Structures Revealed by X-ray Crystallography and Molecular Dynamics Simulation(Protein:Structure & Function, The 47th Annual Meeting of the Biophysical Society of Japan)

    Angkawidjaja Clement, Matsumura Hiroyoshi, Koga Yuichi, Takano Kazufumi, Kanaya Shigenori

    Seibutsu Butsuri Vol. 49 No. 0 2009

    Publisher: The Biophysical Society of Japan General Incorporated Association

Institutional Repository 1

Content Published in the University of Osaka Institutional Repository (OUKA)
  1. Post-Covid International Exchange Through Lateral Cooperation : Osaka University Virtual University Tour as New Practices of Online International Student Recruitment

    Zhang Xixi, Enkhtur Ariunaa, Li Ming, Kai Toshie, Hisada Hitoshi, Angkawidjaja Clement

    Osaka University Higher Education Studies Vol. 11 p. 29-35 2023/03/20