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Multifunctional noncoding regions in the mammarenavirus genome.
Masaharu Iwasaki
Virology Vol. 605 p. 110464-110464 2025年4月 研究論文(学術雑誌)
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U-73122, a phospholipase C inhibitor, impairs lymphocytic choriomeningitis virus virion infectivity.
Keita Mizuma, Mei Hashizume, Shuzo Urata, Keiko Shindo, Ayako Takashima, Satoshi Mizuta, Masaharu Iwasaki
The Journal of general virology Vol. 105 No. 12 2024年12月17日 研究論文(学術雑誌)
出版者・発行元:Microbiology Society
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A facile access to aliphatic trifluoromethyl ketones via photocatalyzed cross-coupling of bromotrifluoroacetone and alkenes.
Satoshi Mizuta, Tomoko Yamaguchi, Masaharu Iwasaki, Takeshi Ishikawa
Organic & biomolecular chemistry Vol. 22 No. 45 p. 8847-8856 2024年11月21日 研究論文(学術雑誌)
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An mRNA-LNP-based Lassa virus vaccine induces protective immunity in mice.
Mei Hashizume, Ayako Takashima, Masaharu Iwasaki
Journal of virology Vol. 98 No. 6 2024年6月13日 研究論文(学術雑誌)
出版者・発行元:American Society for Microbiology
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Phenothiazines inhibit SARS-CoV-2 cell entry via a blockade of spike protein binding to neuropilin-1.
Mei Hashizume, Ayako Takashima, Chikako Ono, Toru Okamoto, Masaharu Iwasaki
Antiviral research Vol. 209 p. 105481-105481 2023年1月 研究論文(学術雑誌)
出版者・発行元:Elsevier BV
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The Pan-ErbB tyrosine kinase inhibitor afatinib inhibits multiple steps of the mammarenavirus life cycle.
Keita Mizuma, Ayako Takashima, Beatrice Cubitt, Juan C de la Torre, Masaharu Iwasaki
Virology Vol. 576 p. 83-95 2022年11月 研究論文(学術雑誌)
出版者・発行元:Elsevier BV
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A small stem-loop-forming region within the 3'-UTR of a nonpolyadenylated LCMV mRNA promotes translation.
Mei Hashizume, Ayako Takashima, Masaharu Iwasaki
The Journal of biological chemistry Vol. 298 No. 2 p. 101576-101576 2022年2月1日 研究論文(学術雑誌)
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Loperamide inhibits replication of severe fever with thrombocytopenia syndrome virus
Shuzo Urata, Jiro Yasuda, Masaharu Iwasaki
Viruses Vol. 13 No. 5 2021年5月10日 研究論文(学術雑誌)
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Population-specific ace2 single-nucleotide polymorphisms have limited impact on sars-cov-2 infectivity in vitro
Mei Hashizume, Gabriel Gonzalez, Chikako Ono, Ayako Takashima, Masaharu Iwasaki
Viruses Vol. 13 No. 1 2021年1月6日 研究論文(学術雑誌)
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A lassa virus live-attenuated vaccine candidate based on rearrangement of the intergenic region
Yingyun Cai, Masaharu Iwasaki, Daisuke Motooka, David X. Liu, Shuiqing Yu, Kurt Cooper, Randy Hart, Ricky Adams, Tracey Burdette, Elena N. Postnikova, Jonathan Kurtz, Marisa St Claire, Chengjin Ye, Jens H. Kuhn, Luis Martínez-Sobrido, Juan Carlos De La Torre
mBio Vol. 11 No. 2 2020年3月 研究論文(学術雑誌)
出版者・発行元:American Society for Microbiology
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Erratum: Correction: Interactome analysis of the lymphocytic choriomeningitis virus nucleoprotein in infected cells reveals ATPase Na+/K+ transporting subunit Alpha 1 and prohibitin as host-cell factors involved in the life cycle of mammarenaviruses (PLoS pathogens (2018) 14 2 (e1006892))
Masaharu Iwasaki, Petra Minder, Yíngyún Caì, Jens H. Kuhn, John R. Yates, Bruce E. Torbett, Juan C. de la Torre
PLoS pathogens Vol. 16 No. 1 2020年1月1日 研究論文(学術雑誌)
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A lassa fever live-attenuated vaccine based on codon deoptimization of the viral glycoprotein gene
Yingyun Cai, Chengjin Ye, Benson Cheng, Aitor Nogales, Masaharu Iwasaki, Shuiqing Yu, Kurt Cooper, David X. Liu, Randy Hart, Ricky Adams, Tyler Brady, Elena N. Postnikova, Jonathan Kurtz, Marisa St Claire, Jens H. Kuhn, Juan Carlos de la Torre, Luis Martínez-Sobrido
mBio Vol. 11 No. 1 2020年 研究論文(学術雑誌)
出版者・発行元:American Society for Microbiology
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Recombinant lassa virus expressing green fluorescent protein as a tool for high-throughput drug screens and neutralizing antibody assays
Yíngyún Caì, Masaharu Iwasaki, Brett F. Beitzel, Shuīqìng Yú, Elena N. Postnikova, Beatrice Cubitt, Lisa Evans Dewald, Sheli R. Radoshitzky, Laura Bollinger, Peter B. Jahrling, Gustavo F. Palacios, Juan C. de la Torre, Jens H. Kuhn
Viruses Vol. 10 No. 11 2018年11月20日 研究論文(学術雑誌)
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A highly conserved leucine in mammarenavirus matrix Z protein is required for Z interaction with the virus L polymerase and Z stability in cells harboring an active viral ribonucleoprotein
Masaharu Iwasaki, Juan C. de la Torre
Journal of Virology Vol. 92 No. 11 2018年6月1日 研究論文(学術雑誌)
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Interactome analysis of the lymphocytic choriomeningitis virus nucleoprotein in infected cells reveals ATPase Na+/K+transporting subunit Alpha 1 and prohibitin as host-cell factors involved in the life cycle of mammarenaviruses
Masaharu Iwasaki, Petra Minder, Yíngyún Caì, Jens H. Kuhn, John R. Yates, Bruce E. Torbett, Juan C. de la Torre
PLoS Pathogens Vol. 14 No. 2 2018年2月 研究論文(学術雑誌)
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Resistance of human plasmacytoid dendritic CAL-1 cells to infection with lymphocytic choriomeningitis virus (LCMV) is caused by restricted virus cell entry, which is overcome by contact of CAL-1 cells with LCMV-infected cells
Masaharu Iwasaki, Siddhartha M. Sharma, Brett S. Marro, Juan C. de la Torre
Virology Vol. 511 p. 106-113 2017年11月 研究論文(学術雑誌)
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Residues K465 and G467 within the cytoplasmic domain of GP2 play a critical role in the persistence of lymphocytic choriomeningitis virus in mice
Masaharu Iwasaki, Cherie T. Ng, Beatrice Cubitt, Juan C. de la Torre
Journal of Virology Vol. 90 No. 22 p. 10102-10112 2016年 研究論文(学術雑誌)
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The high degree of sequence plasticity of the arenavirus noncoding intergenic region (IGR) enables the use of a nonviral universal synthetic IGR to attenuate arenaviruses
Masaharu Iwasaki, Beatrice Cubitt, Brian M. Sullivan, Juan C. De la Torre
Journal of Virology Vol. 90 No. 6 p. 3187-3197 2016年 研究論文(学術雑誌)
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Identification and mechanism of action of a novel small-molecule inhibitor of arenavirus multiplication
Nhi Ngo, Beatrice Cubitt, Masaharu Iwasaki, Juan C. de la Torre
Journal of Virology Vol. 89 No. 21 p. 10924-10933 2015年 研究論文(学術雑誌)
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General molecular strategy for development of arenavirus live-attenuated vaccines
Masaharu Iwasaki, Nhi Ngo, Beatrice Cubitt, John R. Teijaro, Juan C. De la Torre
Journal of Virology Vol. 89 No. 23 p. 12166-12177 2015年 研究論文(学術雑誌)
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Efficient interaction between arenavirus nucleoprotein (NP) and RNA-dependent RNA polymerase (L) is mediated by the virus nucleocapsid (NP-RNA) template
Masaharu Iwasaki, Nhi Ngo, Beatrice Cubitt, Juan C. de la Torre
Journal of Virology Vol. 89 No. 10 p. 5734-5738 2015年 研究論文(学術雑誌)
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Corrigendum to "Cell entry of lymphocytic choriomeningitis virus is restricted in myotubes" [Virology 458-459 (2014) 22-32]
Masaharu Iwasaki, Shuzo Urata, Yoshitake Cho, Nhi Ngo, Juan C. de la Torre
Virology Vol. 458-459 No. 1 2014年6月 研究論文(学術雑誌)
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Cell entry of lymphocytic choriomeningitis virus is restricted in myotubes
Masaharu Iwasaki, Shuzo Urata, Yoshitake Cho, Nhi Ngo, Juan C. De la Torre
Virology Vol. 458-459 No. 1 p. 22-32 2014年6月 研究論文(学術雑誌)
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Sodium hydrogen exchangers contribute to arenavirus cell entry
Masaharu Iwasaki, Nhi Ngo, Juan C. de la Torre
Journal of Virology Vol. 88 No. 1 p. 643-654 2014年1月 研究論文(学術雑誌)
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Intracellular transport of the measles virus ribonucleoprotein complex is mediated by Rab11A-positive recycling endosomes and drives virus release from the apical membrane of polarized epithelial cells
Yuichiro Nakatsu, Xuemin Ma, Fumio Seki, Tadaki Suzuki, Masaharu Iwasaki, Yusuke Yanagi, Katsuhiro Komase, Makoto Takedaa
Journal of Virology Vol. 87 No. 8 p. 4683-4693 2013年4月 研究論文(学術雑誌)
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Measles virus nonstructural C protein modulates viral RNA polymerase activity by interacting with host protein SHCBP1
Minako Ito, Masaharu Iwasaki, Makoto Takeda, Takanori Nakamura, Yusuke Yanagi, Shinji Ohno
Journal of Virology Vol. 87 No. 17 p. 9633-9642 2013年 研究論文(学術雑誌)
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Expression of the Sendai (murine parainfluenza) virus C protein alleviates restriction of measles virus growth in mouse cells
Masaharu Iwasaki, Yusuke Yanagi
Proceedings of the National Academy of Sciences of the United States of America Vol. 108 No. 37 p. 15384-15389 2011年9月13日 研究論文(学術雑誌)
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A highly attenuated measles virus vaccine strain encodes a fully functional C protein
Yuichiro Nakatsu, Makoto Takeda, Masaharu Iwasaki, Yusuke Yanagi
Journal of Virology Vol. 83 No. 22 p. 11996-12001 2009年11月 研究論文(学術雑誌)
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The matrix protein of measles virus regulates viral RNA synthesis and assembly by interacting with the nucleocapsid protein
Masaharu Iwasaki, Makoto Takeda, Yuta Shirogane, Yuichiro Nakatsu, Takanori Nakamura, Yusuke Yanagi
Journal of Virology Vol. 83 No. 20 p. 10374-10383 2009年10月 研究論文(学術雑誌)
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Efficient multiplication of human metapneumovirus in vero cells expressing the transmembrane serine protease TMPRSS2
Yuta Shirogane, Makoto Takeda, Masaharu Iwasaki, Nobuhisa Ishiguro, Hiroki Takeuchi, Yuichiro Nakatsu, Maino Tahara, Hideaki Kikuta, Yusuke Yanagi
Journal of Virology Vol. 82 No. 17 p. 8942-8946 2008年9月 研究論文(学術雑誌)
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Measles virus circumvents the host interferon response by different actions of the C and V proteins
Yuichiro Nakatsu, Makoto Takeda, Shinji Ohno, Yuta Shirogane, Masaharu Iwasaki, Yusuke Yanagi
Journal of Virology Vol. 82 No. 17 p. 8296-8306 2008年9月 研究論文(学術雑誌)