EN

基本情報

研究

社会活動

その他の活動

内川 昌則

Uchikawa Masanori

生命機能研究科 生命機能専攻,助教

keyword 感覚器,遺伝子発現制御,細胞分化,胚発生,分子生物学,発生生物学

研究内容・専門分野

  • ライフサイエンス,発生生物学
  • ライフサイエンス,分子生物学

所属学会

  • 日本分子生物学会
  • 日本発生生物学会
  • The Japanese Society of Developmental Biologists
  • The Molecular Biology Society of Japan

論文

  • The many faces of Sox2 function in neural crest development,Yoshio Wakamatsu,Masanori Uchikawa,Development, Growth & Differentiation,Wiley,Vol. 63,No. 1,p. 93-99,2021年01月,研究論文(学術雑誌)
  • Sox2 gene regulation via the D1 enhancer in embryonic neural tube and neural crest by the combined action of SOX2 and ZIC2.,Hideaki Iida,Yoko Furukawa,Machiko Teramoto,Hitomi Suzuki,Tatsuya Takemoto,Masanori Uchikawa,Hisato Kondoh,Genes to cells : devoted to molecular & cellular mechanisms,Vol. 25,No. 4,p. 242-256,2020年04月,研究論文(学術雑誌)
  • The absence of SOX2 in the anterior foregut alters the esophagus into trachea and bronchi in both epithelial and mesenchymal components.,Machiko Teramoto,Ryo Sugawara,Katsura Minegishi,Masanori Uchikawa,Tatsuya Takemoto,Atsushi Kuroiwa,Yasuo Ishii,Hisato Kondoh,Biology open,Vol. 9,No. 2,2020年02月07日,研究論文(学術雑誌)
  • Nodal paralogues underlie distinct mechanisms for visceral left–right asymmetry in reptiles and mammals,Eriko Kajikawa,Uzuki Horo,Takahiro Ide,Katsutoshi Mizuno,Katsura Minegishi,Yuichiro Hara,Yayoi Ikawa,Hiromi Nishimura,Masanori Uchikawa,Hiroshi Kiyonari,Shigehiro Kuraku,Hiroshi Hamada,Nature Ecology & Evolution,Vol. 4,No. 2,p. 261-269,2020年02月,研究論文(学術雑誌)
  • Cooperation of Sall4 and Sox8 transcription factors in the regulation of the chicken Sox3 gene during otic placode development,Yu Okamoto,Naoko Nishimura,Kazunari Matsuda,Deshani C. Ranawakage,Yusuke Kamachi,Hisato Kondoh,Masanori Uchikawa,Development Growth and Differentiation,Blackwell Publishing,Vol. 60,No. 3,p. 133-145,2018年04月01日,研究論文(学術雑誌)
  • Nasal and otic placode specific regulation of Sox2 involves both activation by Sox-Sall4 synergism and multiple repression mechanisms,Satoko Sugahara,Tooru Fujimoto,Hisato Kondoh,Masanori Uchikawa,Developmental Biology,Elsevier Inc.,Vol. 433,No. 1,p. 61-74,2018年01月01日,研究論文(学術雑誌)
  • Enhancer analyses using chicken embryo electroporation,Masanori Uchikawa,Naoko Nishimura,Makiko Iwafuchi-Doi,Hisato Kondoh,Methods in Molecular Biology,Humana Press Inc.,Vol. 1650,p. 191-202,2017年,論文集(書籍)内論文
  • Regulation of trunk neural crest delamination by δEF1 and Sip1 in the chicken embryo.,Yasumi, T,Inoue, M,Maruhashi, M,Kamachi, Y,Higashi, Y,Kondoh, H,Uchikawa, M,Development, growth & differentiation,Vol. 58,No. 2,p. 205-214,2016年02月,研究論文(学術雑誌)
  • Regulation of Sox2 via Many Enhancers of Distinct Specificities,Masanori Uchikawa,Hisato Kondoh,Sox2: Biology and Role in Development and Disease,Elsevier Inc.,Vol. 7,p. 107-129,2015年01月01日,論文集(書籍)内論文
  • Multiple Roles for SOX2 in Eye Development,Hisato Kondoh,Masanori Uchikawa,Yasuo Ishii,Sox2: Biology and Role in Development and Disease,Elsevier Inc.,Vol. 12,p. 217-233,2015年01月01日,論文集(書籍)内論文
  • Sixteen additional enhancers associated with the chicken Sox2 locus outside the central 50-kb region,Ryuji Okamoto,Masanori Uchikawa,Hisato Kondoh,DEVELOPMENT GROWTH & DIFFERENTIATION,WILEY-BLACKWELL,Vol. 57,No. 1,p. 24-39,2015年01月,研究論文(学術雑誌)
  • Regulation of mesodermal precursor production by low-level expression of B1 Sox genes in the caudal lateral epiblast,Megumi Yoshida,Masanori Uchikawa,Karine Rizzoti,Robin Lovell-Badge,Tatsuya Takemoto,Hisato Kondoh,MECHANISMS OF DEVELOPMENT,ELSEVIER SCIENCE BV,Vol. 132,p. 59-68,2014年05月,研究論文(学術雑誌)
  • Progression of Neurogenesis in the Inner Ear Requires Inhibition of Sox2 Transcription by Neurogenin1 and Neurod1,Lale Evsen,Satoko Sugahara,Masanori Uchikawa,Hisato Kondoh,Doris K. Wu,JOURNAL OF NEUROSCIENCE,SOC NEUROSCIENCE,Vol. 33,No. 9,p. 3879-3890,2013年02月,研究論文(学術雑誌)
  • A systematic survey and characterization of enhancers that regulate Sox3 in neuro-sensory development in comparison with Sox2 enhancers,Naoko Nishimura,Yoshifumi Kamimura,Yoshiko Ishida,Tatsuya Takemoto,Hisato Kondoh,Masanori Uchikawa,Biology,MDPI AG,Vol. 1,No. 3,p. 714-735,2012年10月22日,研究論文(学術雑誌)
  • The Prosensory Function of Sox2 in the Chicken Inner Ear Relies on the Direct Regulation of Atoh1,Joana Neves,Masanori Uchikawa,Anna Bigas,Fernando Giraldez,PLOS ONE,PUBLIC LIBRARY SCIENCE,Vol. 7,No. 1,2012年01月,研究論文(学術雑誌)
  • B1 and B2 Sox gene expression during neural plate development in chicken and mouse embryos: Universal versus species-dependent features,Masanori Uchikawa,Megumi Yoshida,Makiko Iwafuchi-Doi,Kazunari Matsuda,Yoshiko Ishida,Tatsuya Takemoto,Hisato Kondoh,DEVELOPMENT GROWTH & DIFFERENTIATION,WILEY-BLACKWELL,Vol. 53,No. 6,p. 761-771,2011年08月,研究論文(学術雑誌)
  • The Pou5f1/Pou3f-dependent but SoxB-independent regulation of conserved enhancer N2 initiates Sox2 expression during epiblast to neural plate stages in vertebrates,Makiko Iwafuchi-Doi,Yuzo Yoshida,Daria Onichtchouk,Manuel Leichsenring,Wolfgang Driever,Tatsuya Takemoto,Masanori Uchikawa,Yusuke Kamachi,Hisato Kondoh,DEVELOPMENTAL BIOLOGY,ACADEMIC PRESS INC ELSEVIER SCIENCE,Vol. 352,No. 2,p. 354-366,2011年04月,研究論文(学術雑誌)
  • Tbx6-dependent Sox2 regulation determines neural or mesodermal fate in axial stem cells,Tatsuya Takemoto,Masanori Uchikawa,Megumi Yoshida,Donald M. Bell,Robin Lovell-Badge,Virginia E. Papaioannou,Hisato Kondoh,NATURE,NATURE PUBLISHING GROUP,Vol. 470,No. 7334,p. 394-398,2011年02月,研究論文(学術雑誌)
  • A gene regulatory network that underlies the derivation of the anterior neural plate from the epiblast,Makiko Iwafuchi-Doi,Tatsuya Takemoto,Yuzo Yoshida,Isao Matsuo,Jun Aruga,Yusuke Kamachi,Masanori Uchikawa,Hisato Kondoh,DEVELOPMENTAL BIOLOGY,ACADEMIC PRESS INC ELSEVIER SCIENCE,Vol. 344,No. 1,p. 495-495,2010年08月
  • Regulation of Sox2 in the pre-placodal cephalic ectoderm and central nervous system by enhancer N-4,Yuka Saigou,Yoshifumi Kamimura,Masashi Inoue,Hisato Kondoh,Masanori Uchikawa,DEVELOPMENT GROWTH & DIFFERENTIATION,WILEY-BLACKWELL,Vol. 52,No. 5,p. 397-408,2010年06月,研究論文(学術雑誌)
  • Evolution of non-coding regulatory sequences involved in the developmental process: Reflection of differential employment of paralogous genes as highlighted by Sox2 and group B1 Sox genes,Yusuke Kamachi,Makiko Iwafuchi,Yuichi Okuda,Tatsuya Takemoto,Masanori Uchikawa,Hisato Kondoh,PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES,JAPAN ACAD,Vol. 85,No. 2,p. 55-68,2009年02月,研究論文(学術雑誌)
  • Enhancer analysis strategies for locus-wide identification and systematic analysis of enhancers using chicken embryo electroporation,Masanori Uchikawa,Tatsuya Takemoto,Electroporation and Sonoporation in Developmental Biology,Springer Japan,Vol. 7,p. 55-71,2009年,論文集(書籍)内論文
  • Neogenin regulates neuronal survival through DAP kinase,Y. Fujita,J. Taniguchi,M. Uchikawa,M. Endo,K. Hata,T. Kubo,B. K. Mueller,T. Yamashita,CELL DEATH AND DIFFERENTIATION,NATURE PUBLISHING GROUP,Vol. 15,No. 10,p. 1593-1608,2008年10月,研究論文(学術雑誌)
  • Enhancer analysis by chicken embryo electroporation with aid of genome comparison,Masanori Uchikawa,DEVELOPMENT GROWTH & DIFFERENTIATION,BLACKWELL PUBLISHING,Vol. 50,No. 6,p. 467-474,2008年08月,研究論文(学術雑誌)
  • Anteroventrally localized activity in the optic vesicle plays a crucial role in the optic development,Miki Hirashima,Takuma Kobayashi,Masanori Uchikawa,Hisato Kondoh,Masasuke Araki,DEVELOPMENTAL BIOLOGY,ACADEMIC PRESS INC ELSEVIER SCIENCE,Vol. 317,No. 2,p. 620-631,2008年05月,研究論文(学術雑誌)
  • Nuclear RNA export factor 7 is localized in processing bodies and neuronal RNA granules through interactions with shuttling hnRNPs,Jun Katahira,Takashi Miki,Keizo Takano,Mitsuji Maruhashi,Masanori Uchikawa,Taro Tachibana,Yoshihiro Yoneda,NUCLEIC ACIDS RESEARCH,OXFORD UNIV PRESS,Vol. 36,No. 2,p. 616-628,2008年02月,研究論文(学術雑誌)
  • Dissection of chick genomic regulatory regions,Hisato Kondoh,Masanori Uchikawa,AVIAN EMBRYOLOGY, 2ND EDITION,ELSEVIER ACADEMIC PRESS INC,Vol. 87,p. 313-+,2008年,論文集(書籍)内論文
  • PAX6 and SOX2-dependent regulation of the Sox2 enhancer N-3 involved in embryonic visual system development,Masashi Inoue,Yusuke Kamachi,Hideyuki Matsunami,Katsumi Imada,Masanori Uchikawa,Hisato Kondoh,GENES TO CELLS,BLACKWELL PUBLISHING,Vol. 12,No. 9,p. 1049-1061,2007年09月,研究論文(学術雑誌)
  • Identification of a prosencephalic-specific enhancer of SALL1: Comparative genomic approach using the chick embryo,Kosuke Izumi,Michihiko Aramaki,Tokuhiro Kimura,Yoko Naito,Toru Udaka,Masanori Uchikawa,Hisato Kondoh,Hidekazu Suzuki,Ginam Cho,Yasunori Okada,Takao Takahashi,Jeffrey A. Golden,Kenjiro Kosaki,PEDIATRIC RESEARCH,INT PEDIATRIC RESEARCH FOUNDATION, INC,Vol. 61,No. 6,p. 660-665,2007年06月,研究論文(学術雑誌)
  • Comparative genomic and expression analysis of group B1 sox genes in zebrafish indicates their diversification during vertebrate evolution,Y Okuda,H Yoda,M Uchikawa,M Furutani-Seiki,H Takeda,H Kondoh,Y Kamachi,DEVELOPMENTAL DYNAMICS,WILEY-LISS,Vol. 235,No. 3,p. 811-825,2006年03月,研究論文(学術雑誌)
  • Convergence of Wnt and FGF signals in the genesis of posterior neural plate through activation of the Sox2 enhancer N-1,T Takemoto,M Uchikawa,Y Kamachi,H Kondoh,DEVELOPMENT,COMPANY OF BIOLOGISTS LTD,Vol. 133,No. 2,p. 297-306,2006年01月,研究論文(学術雑誌)
  • Multiple N-cadherin enhancers identified by systematic functional screening indicate its Group B1SOX-dependent regulation in neural and placodal development,M Matsumata,M Uchikawa,Y Kamachi,H Kondoh,DEVELOPMENTAL BIOLOGY,ACADEMIC PRESS INC ELSEVIER SCIENCE,Vol. 286,No. 2,p. 601-617,2005年10月,研究論文(学術雑誌)
  • Efficient identification of regulatory sequences in the chicken genome by a powerful combination of embryo electroporation and genome comparison,M Uchikawa,T Takemoto,Y Kamachi,H Kondoh,MECHANISMS OF DEVELOPMENT,ELSEVIER SCIENCE BV,Vol. 121,No. 9,p. 1145-1158,2004年09月,研究論文(学術雑誌)
  • Interplay of Pax6 and SOX2 in lens development as a paradigm of genetic switch mechanisms for cell differentiation,H Kondoh,M Uchikawa,Y Kamachi,INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY,U B C PRESS,Vol. 48,No. 8-9,p. 819-827,2004年,研究論文(学術雑誌)
  • Functional analysis of chicken Sox2 enhancers highlights an array of diverse regulatory elements that are conserved in mammals,M Uchikawa,Y Ishida,T Takemoto,Y Kamachi,H Kondoh,DEVELOPMENTAL CELL,CELL PRESS,Vol. 4,No. 4,p. 509-519,2003年04月,研究論文(学術雑誌)
  • Six3-mediated auto repression and eye development requires its interaction with members of the Groucho-related family of co-repressors,CQC Zhu,MA Dyer,M Uchikawa,H Kondoh,OV Lagutin,G Oliver,DEVELOPMENT,COMPANY OF BIOLOGISTS LTD,Vol. 129,No. 12,p. 2835-2849,2002年06月,研究論文(学術雑誌)
  • Chromosome assignment of eight SOX family genes in chicken,A Kuroiwa,M Uchikawa,Y Kamamchi,H Kondoh,C Nishida-Umehara,J Masabanda,DK Griffin,Y Matsuda,CYTOGENETIC AND GENOME RESEARCH,KARGER,Vol. 98,No. 2-3,p. 189-193,2002年,研究論文(学術雑誌)
  • Pax6 and SOX2 form a co-DNA-binding partner complex that regulates initiation of lens development,Y Kamachi,M Uchikawa,A Tanouchi,R Sekido,H Kondoh,GENES & DEVELOPMENT,COLD SPRING HARBOR LAB PRESS,Vol. 15,No. 10,p. 1272-1286,2001年05月,研究論文(学術雑誌)
  • Zebrafish mutations in Gli-mediated hedgehog signaling lead to lens transdifferentiation from the adenohypophysis anlage,H Kondoh,M Uchikawa,H Yoda,H Takeda,M Furutani-Seiki,RO Karlstrom,MECHANISMS OF DEVELOPMENT,ELSEVIER SCIENCE BV,Vol. 96,No. 2,p. 165-174,2000年09月,研究論文(学術雑誌)
  • Zebrafish mutations in Gli-mediated hedgehog signaling lead to lens transdifferentiation from the adenohypophysis anlage,Hisato Kondoh,Masanori Uchikawa,Hiroki Yoda,Hiroyuki Takeda,Makoto Furutani-Seiki,Rolf O. Karlstrom,Obstetrics and Gynecology,Vol. 96,No. 3,p. 165-174,2000年08月23日,研究論文(学術雑誌)
  • Pairing SOX off with partners in the regulation of embryonic development,Y Kamachi,M Uchikawa,H Kondoh,TRENDS IN GENETICS,ELSEVIER SCIENCE LONDON,Vol. 16,No. 4,p. 182-187,2000年04月,研究論文(学術雑誌)
  • Two distinct subgroups of Group B Sox genes for transcriptional activators and repressors: their expression during embryonic organogenesis of the chicken,M Uchikawa,Y Kamachi,H Kondoh,MECHANISMS OF DEVELOPMENT,ELSEVIER SCIENCE BV,Vol. 84,No. 1-2,p. 103-120,1999年06月,研究論文(学術雑誌)
  • Involvement of Sox1, 2 and 3 in the early and subsequent molecular events of lens induction,Y Kamachi,M Uchikawa,J Collignon,R Lovell-Badge,H Kondoh,DEVELOPMENT,COMPANY OF BIOLOGISTS LTD,Vol. 125,No. 13,p. 2521-2532,1998年07月,研究論文(学術雑誌)

MISC

  • Sox2 and Ngn1 regulate the neurogenic fate in the developing inner ear,Lale Evsen,Masanori Uchikawa,Satoko Sugahara,Hisato Kondoh,Doris Wu,DEVELOPMENTAL BIOLOGY,ACADEMIC PRESS INC ELSEVIER SCIENCE,Vol. 356,No. 1,p. 179-179,2011年08月,研究発表ペーパー・要旨(国際会議)
  • The role of Sox2 in the regulation of eye development,Masanori Uchikawa,Miho Morishima,Yuka Saigou,Hisato Kondoh,DEVELOPMENTAL BIOLOGY,ACADEMIC PRESS INC ELSEVIER SCIENCE,Vol. 344,No. 1,p. 484-484,2010年08月,研究発表ペーパー・要旨(国際会議)
  • Enhancer N-1-dependent activation of Sox2 during caudal extension of the neural plate and its downstream molecular events,Megumi Yoshida,Tatsuya Takemoto,Masanori Uchikawa,Hisato Kondoh,DEVELOPMENTAL BIOLOGY,ACADEMIC PRESS INC ELSEVIER SCIENCE,Vol. 344,No. 1,p. 464-464,2010年08月,研究発表ペーパー・要旨(国際会議)
  • Tbx6-dependent regulation of Sox2 enhancer N1 determines the neural vs. mesodermal fate of axial stem cells in the caudal lateral epiblast,Tatsuya Takemoto,Masanori Uchikawa,Robin Lovell-Badge,Virginia Papaioannou,Hisato Kondoh,DEVELOPMENTAL BIOLOGY,ACADEMIC PRESS INC ELSEVIER SCIENCE,Vol. 344,No. 1,p. 503-503,2010年08月,研究発表ペーパー・要旨(国際会議)
  • Anterior and posterior neural plates from epiblast are derived by distinct molecular mechanisms,Hisato Kondoh,M. Iwafuchi,M. Yoshida,V. E. Papaioannou,R. Lovell-Badge,M. Uchikawa,T. Takemoto,DEVELOPMENTAL BIOLOGY,ACADEMIC PRESS INC ELSEVIER SCIENCE,Vol. 331,No. 2,p. 391-391,2009年07月,研究発表ペーパー・要旨(国際会議)
  • A transition in Sox2 gene regulation distinguishes the epiblastic and anterior neural plate states,Makiko Iwafuchi,Tatsuya Takemoto,Masanori Uchikawa,Yusuke Kamachi,Hisato Kondoh,DEVELOPMENTAL BIOLOGY,ACADEMIC PRESS INC ELSEVIER SCIENCE,Vol. 319,No. 2,p. 593-593,2008年07月,研究発表ペーパー・要旨(国際会議)
  • Regulation of Sox2 in the development of eye primordia,M. Inoue,M. Uchikawa,Y. Kamachi,H. Kondoh,MECHANISMS OF DEVELOPMENT,ELSEVIER SCIENCE BV,Vol. 122,p. S169-S169,2005年09月,研究発表ペーパー・要旨(国際会議)
  • Regulation of Sox2 gene in early neural development,M. Uchikawa,T. Takemoto,M. Iwafuchi,Y. Yoshida,Y. Kamachi,H. Kondoh,MECHANISMS OF DEVELOPMENT,ELSEVIER SCIENCE BV,Vol. 122,p. S167-S167,2005年09月,研究発表ペーパー・要旨(国際会議)
  • Zebrafish B1 sox genes revealing evolutional diversification of function and expression profiles,Y. Okuda,M. Uchikawa,H. Kondoh,Y. Kamachi,MECHANISMS OF DEVELOPMENT,ELSEVIER SCIENCE BV,Vol. 122,p. S156-S156,2005年09月,研究発表ペーパー・要旨(国際会議)
  • Mechanisms of neural induction and patterning illuminated by the regulation of Sox2 enhancers,H. Kondoh,T. Takemoto,M. Inoue,M. Iwafuchi,Y. Yoshida,Y. Kamachi,M. Uchikawa,MECHANISMS OF DEVELOPMENT,ELSEVIER SCIENCE BV,Vol. 122,p. S175-S175,2005年09月,研究発表ペーパー・要旨(国際会議)
  • クリスタリン遺伝子の発現制御から解明された水晶体分化,内川昌則,蒲池雄介,近藤寿人,蛋白質 核酸 酵素,共立出版,Vol. 50,No. 6,p. 655-663,2005年05月,記事・総説・解説・論説等(学術雑誌)
  • Understanding lens differentiation from the analysis of crystallin gene regulation.,Tanpakushitsu Kakusa Koso,Vol. 50, 6 Suppl,2005年
  • Understanding lens differentiation from the analysis of crystallin gene regulation.,Tanpakushitsu Kakusa Koso,Vol. 50, 6 Suppl/,,2005年
  • HMGドメイン,内川昌則,生体の科学,Vol. 52,No. 5,p. 379-381,2001年09月,記事・総説・解説・論説等(学術雑誌)
  • SOXとパートナー因子による転写調節機構,内川昌則,蒲池雄介,近藤寿人,細胞工学,秀潤社,Vol. 20,No. 5,p. 729-739,2001年05月,記事・総説・解説・論説等(学術雑誌)
  • Zebrafish mutations in Gli-mediated hedgehog signaling lead to lens transdifferentiation from the adenohypophysis anlage,H Kondoh,M Uchikawa,H Yoda,H Takeda,M Furutani-Seiki,RO Karlstrom,MECHANISMS OF DEVELOPMENT,ELSEVIER SCIENCE BV,Vol. 96,No. 2,p. 165-174,2000年09月
  • Two distinct subgroups of Group B Sox genes for transcriptional activators and repressors: Their expression during embryonic organogenesis of the chicken,Masanori Uchikawa,Yusuke Kamachi,Hisato Kondoh,Mechanisms of Development,Vol. 84,No. 1-2,p. 103-120,1999年06月01日
  • ゼブラフィッシュSox遺伝子群とその発現,依田 宏樹,内川 昌則,蒲池 雄介,武田 洋幸,近藤 寿人,日本分子生物学会年会プログラム・講演要旨集,Vol. 21,p. 622-622,1998年12月01日
  • How the specificity of the SOX HMG domain proteins is determined in transcriptional activation.,Y Kamachi,M Uchikawa,H Kondoh,DEVELOPMENTAL BIOLOGY,ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS,Vol. 186,No. 2,p. A120-A120,1997年06月,研究発表ペーパー・要旨(国際会議)
  • Coexpression of Pax6 and Sox2/3 as a condition of lens differentiation,H Kondoh,M Uchikawa,Y Kamachi,H Takeda,M FurutaniSeiki,R Karlstrom,DEVELOPMENTAL BIOLOGY,ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS,Vol. 186,No. 2,p. S26-S26,1997年06月,研究発表ペーパー・要旨(国際会議)