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Local treatment of HVJ-E with T cell costimulatory molecule stimulation elicits systemic anti-tumor effects.
Airi Ishibashi, Yue Li, Yuuta Hisatomi, Noriko Ohta, Yuko Uegaki, Atsushi Tanemura, Riuko Ohashi, Koji Kitamura, Kotaro Saga, Yasuhide Yoshimura, Satoko Inubushi, Kyoso Ishida, Sadahiro Iwabuchi, Shinichi Hashimoto, Eiji Kiyohara, Hideo Yagita, Yasufumi Kaneda, Keisuke Nimura
Molecular therapy. Oncology Vol. 32 No. 4 p. 200893-200893 2024年12月19日 研究論文(学術雑誌)
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Dose-escalation, tolerability, and efficacy of intratumoral and subcutaneous injection of hemagglutinating virus of Japan envelope (HVJ-E) against chemotherapy-resistant malignant pleural mesothelioma: a clinical trial
Kazuma Sakura, Muneyoshi Kuroyama, Yasushi Shintani, Soichiro Funaki, Shinji Atagi, Yoshihisa Kadota, Kozo Kuribayashi, Takashi Kijima, Takashi Nakano, Toshihiro Nakajima, Masao Sasai, Meinoshin Okumura, Yasufumi Kaneda
Cancer Immunology, Immunotherapy Vol. 73 No. 12 2024年10月3日 研究論文(学術雑誌)
出版者・発行元:Springer Science and Business Media LLC
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(S)-(-)-blebbistatin O-benzoate has the potential to improve atopic dermatitis symptoms in NC/Nga mice by upregulating epidermal barrier function and inhibiting type 2 alarmin cytokine induction.
Shunya Sahara, Ayumi Ueno, Natsuki Wakita, Miki Iwai, Junki Uda, Koich Nakaoji, Kazuhiko Hamada, Akito Maeda, Yasufumi Kaneda, Manabu Fujimoto
PloS one Vol. 19 No. 5 2024年 研究論文(学術雑誌)
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Gene-Modified Blister Fluid-Derived Mesenchymal Stromal Cells for Treating Recessive Dystrophic Epidermolysis Bullosa.
Yasushi Kikuchi, Tomoki Tamakoshi, Ryuichi Ishida, Ryosuke Kobayashi, Shiho Mori, Akemi Ishida-Yamamoto, Manabu Fujimoto, Yasufumi Kaneda, Katsuto Tamai
The Journal of investigative dermatology 2023年6月10日 研究論文(学術雑誌)
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Add-On Effect of Hemagglutinating Virus of Japan Envelope Combined with Chemotherapy or Immune Checkpoint Inhibitor against Malignant Pleural Mesothelioma: An In Vivo Study.
Kazuma Sakura, Masao Sasai, Soichiro Funaki, Yasushi Shintani, Meinoshin Okumura, Yasufumi Kaneda
Cancers Vol. 15 No. 3 2023年2月1日 研究論文(学術雑誌)
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DNA barcoding and gene expression recording reveal the presence of cancer cells with unique properties during tumor progression.
Yuka Umeki, Noriaki Ogawa, Yuko Uegaki, Kotaro Saga, Yasufumi Kaneda, Keisuke Nimura
Cellular and molecular life sciences : CMLS Vol. 80 No. 1 p. 17-17 2022年12月23日 研究論文(学術雑誌)
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Novel pathophysiological roles of α‐synuclein in age‐related vascular endothelial dysfunction
Yoichi Takami, Cheng Wang, Hironori Nakagami, Koichi Yamamoto, Yoichi Nozato, Yuki Imaizumi, Motonori Nagasawa, Hikari Takeshita, Tsuneo Nakajima, Shuko Takeda, Yasushi Takeya, Yasufumi Kaneda, Hiromi Rakugi
The FASEB Journal Vol. 36 No. 10 2022年10月 研究論文(学術雑誌)
出版者・発行元:Wiley
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前立腺癌におけるアンドロゲン受容体研究の最前線 前立腺癌におけるAndrogen receptor splicing variant 7(AR-V7)の発現機構の解明 新たな治療方法を目指して
川村 憲彦, 二村 圭祐, 石井 信, 吉村 明洋, 山本 致之, 永原 啓, 中井 康友, 中山 雅志, 金田 安史, 野々村 祝夫, 西村 和郎
泌尿器外科 Vol. 35 No. 8 p. 885-887 2022年8月
出版者・発行元:医学図書出版(株)
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A phase I dose-escalation, safety/tolerability, and preliminary efficacy study of the intratumoral administration of GEN0101 in patients with advanced melanoma
Eiji Kiyohara, Atsushi Tanemura, Kazuma Sakura, Toshihiro Nakajima, Akira Myoui, Naoya Yamazaki, Yoshio Kiyohara, Ichiro Katayama, Manabu Fujimoto, Yasufumi Kaneda
Cancer Immunology, Immunotherapy Vol. 71 No. 8 p. 2041-2049 2022年8月 研究論文(学術雑誌)
出版者・発行元:Springer Science and Business Media LLC
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Identification of Malignant Cell Populations Associated with Poor Prognosis in High-Grade Serous Ovarian Cancer Using Single-Cell RNA Sequencing.
Naoki Sumitani, Kyoso Ishida, Kenjiro Sawada, Tadashi Kimura, Yasufumi Kaneda, Keisuke Nimura
Cancers Vol. 14 No. 15 2022年7月22日 研究論文(学術雑誌)
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Dual function of SF3B2 on chromatin and RNA to regulate transcription in head and neck squamous cell carcinoma.
Koji Kitamura, Hidefumi Suzuki, Ryota Abe, Hidenori Inohara, Yasufumi Kaneda, Hidehisa Takahashi, Keisuke Nimura
Cell & bioscience Vol. 12 No. 1 p. 92-92 2022年6月17日 研究論文(学術雑誌)
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Author Correction: Evaluation of HPV16 E7 expression in head and neck carcinoma cell lines and clinical specimens (Scientific Reports, (2020), 10, 1, (22138), 10.1038/s41598-020-78345-8)
Koji Kitamura, Keisuke Nimura, Rie Ito, Kotaro Saga, Hidenori Inohara, Yasufumi Kaneda
Scientific Reports Vol. 11 No. 1 2021年12月1日 研究論文(学術雑誌)
出版者・発行元:Nature Research
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Longitudinal Single-Cell Transcriptomics Reveals a Role for Serpina3n-Mediated Resolution of Inflammation in a Mouse Colitis Model.
Yen-Ting Ho, Takashi Shimbo, Edward Wijaya, Tomomi Kitayama, Satoshi Takaki, Kentaro Ikegami, Kazuya Miyashita, Yuya Ouchi, Eiichi Takaki, Ryoma Yamamoto, Yasufumi Kaneda, Katsuto Tamai
Cellular and molecular gastroenterology and hepatology Vol. 12 No. 2 p. 547-566 2021年4月13日 研究論文(学術雑誌)
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CXCL2 combined with HVJ-E suppresses tumor growth and lung metastasis in breast cancer and enhances anti-PD-1 antibody therapy
Yi Chun Pan, Tomoyuki Nishikawa, Chin Yang Chang, Jiayu A. Tai, Yasufumi Kaneda
Molecular Therapy - Oncolytics Vol. 20 p. 175-186 2021年3月 研究論文(学術雑誌)
出版者・発行元:Elsevier BV
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Hemagglutinating virus of Japan‐envelope containing programmed cell death‐ligand 1 siRNA inhibits immunosuppressive activities and elicits antitumor immune responses in glioma
Narushi Sugii, Masahide Matsuda, Genki Okumura, Akira Shibuya, Eiichi Ishikawa, Yasufumi Kaneda, Akira Matsumura
Cancer Science Vol. 112 No. 1 p. 81-90 2021年1月 研究論文(学術雑誌)
出版者・発行元:Wiley
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CRISPRスクリーニングによる前立腺癌におけるPARPの合成致死遺伝子の網羅的探索
石津谷 祐, 植村 元秀, 松下 慎, 中野 剛佑, 林 裕次郎, 加藤 大悟, 波多野 浩士, 河嶋 厚成, 氏家 剛, 藤田 和利, 二村 圭佑, 金田 安史, 野々村 祝夫
日本泌尿器科学会総会 Vol. 108回 p. 861-861 2020年12月
出版者・発行元:(一社)日本泌尿器科学会総会事務局
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CRISPRスクリーニングによる前立腺癌におけるPARPの合成致死遺伝子の網羅的探索
石津谷 祐, 植村 元秀, 松下 慎, 中野 剛佑, 林 裕次郎, 加藤 大悟, 波多野 浩士, 河嶋 厚成, 氏家 剛, 藤田 和利, 二村 圭佑, 金田 安史, 野々村 祝夫
日本泌尿器科学会総会 Vol. 108回 p. 861-861 2020年12月
出版者・発行元:(一社)日本泌尿器科学会総会事務局
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Evaluation of HPV16 E7 expression in head and neck carcinoma cell lines and clinical specimens
Koji Kitamura, Keisuke Nimura, Rie Ito, Kotaro Saga, Hidenori Inohara, Yasufumi Kaneda
Scientific Reports Vol. 10 No. 1 2020年12月 研究論文(学術雑誌)
出版者・発行元:Springer Science and Business Media LLC
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A simple method using CRISPR-Cas9 to knock-out genes in murine cancerous cell lines
Airi Ishibashi, Kotaro Saga, Yuuta Hisatomi, Yue Li, Yasufumi Kaneda, Keisuke Nimura
Scientific Reports Vol. 10 No. 1 2020年12月 研究論文(学術雑誌)
出版者・発行元:Springer Science and Business Media LLC
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Correction to: Efficient photodynamic therapy against drug-resistant prostate cancer using replication-deficient virus particles and talaporfin sodium.
Sharmin Akter, Sachiko Saito, Mizuho Inai, Norihiro Honda, Hisanao Hazama, Tomoyuki Nishikawa, Yasufumi Kaneda, Kunio Awazu
Lasers in medical science 2020年7月13日
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Efficient photodynamic therapy against drug-resistant prostate cancer using replication-deficient virus particles and talaporfin sodium.
Sharmin Akter, Sachiko Saito, Mizuho Inai, Norihiro Honda, Hisanao Hazama, Tomoyuki Nishikawa, Yasufumi Kaneda, Kunio Awazu
Lasers in medical science 2020年6月27日 研究論文(学術雑誌)
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Cancer immunotherapy using the Fusion gene of Sendai virus.
Jiayu A Tai, Chin Yang Chang, Tomoyuki Nishikawa, Yasufumi Kaneda
Cancer gene therapy Vol. 27 No. 6 p. 498-508 2020年6月 研究論文(学術雑誌)
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Design and Synthesis of 1,2-Deoxy-pyranose Derivatives of Spliceostatin A toward Prostate Cancer Treatment
Yusuke Yoshikawa, Airi Ishibashi, Tsunayoshi Takehara, Takeyuki Suzuki, Kenichi Murai, Yasufumi Kaneda, Keisuke Nimura, Mitsuhiro Arisawa
ACS MEDICINAL CHEMISTRY LETTERS Vol. 11 No. 6 p. 1310-1315 2020年6月 研究論文(学術雑誌)
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Intratumoral injection of hemagglutinating virus of Japan-envelope vector yielded an antitumor effect for advanced melanoma: a phase I/IIa clinical study
Eiji Kiyohara, Atsushi Tanemura, Megumi Nishioka, Mizuho Yamada, Aya Tanaka, Akinori Yokomi, Atsuhiro Saito, Kazuma Sakura, Toshihiro Nakajima, Akira Myoui, Toshiharu Sakurai, Yutaka Kawakami, Yasufumi Kaneda, Ichiro Katayama
Cancer Immunology, Immunotherapy Vol. 69 No. 6 p. 1131-1140 2020年6月 研究論文(学術雑誌)
出版者・発行元:Springer Science and Business Media LLC
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Intratumoral and subcutaneous injection of HVJ-E (GEN0101) in metastatic castration-resistant prostate cancer.
Kazutoshi Fujita, Taigo Kato, Koji Hatano, Atsunari Kawashima, Takeshi Ujike, Motohide Uemura, Ryoichi Imamura, Koji Okihara, Osamu Ukimura, Tsuneharu Miki, Toshihiro Nakajima, Yasufumi Kaneda, Norio Nonomura
Cancer science Vol. 111 No. 5 p. 1692-1698 2020年2月29日 研究論文(学術雑誌)
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Enhancement of ionization efficiency using zeolite in matrix-assisted laser desorption/ionization mass spectrometry of multiple drugs in cancer cells (Mass spectrometry of multiple drugs in cells using zeolite)
Hiroki Kannen, Shusei Nomura, Hisanao Hazama, Yasufumi Kaneda, Tatsuya Fujino, Kunio Awazu
Mass Spectrometry Vol. 9 No. 1 p. 1-6 2020年 研究論文(学術雑誌)
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Photodynamic therapy by lysosomal-targeted drug delivery using talaporfin sodium incorporated into inactivated virus particles.
Sharmin Akter, Mizuho Inai, Sachiko Saito, Norihiro Honda, Hisanao Hazama, Tomoyuki Nishikawa, Yasufumi Kaneda, Kunio Awazu
Laser therapy Vol. 28 No. 4 p. 245-256 2019年12月31日 研究論文(学術雑誌)
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Design and synthesis of a phenyl C-glycoside derivative of Spliceostatin A and its biological evaluation toward prostate cancer treatment
Yusuke Yoshikawa, Airi Ishibashi, Kenichi Murai, Yasufumi Kaneda, Keisuke Nimura, Mitsuhiro Arisawa
Tetrahedron Letters Vol. 60 No. 51 2019年12月19日 研究論文(学術雑誌)
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Stable Immune Response Induced by Intradermal DNA Vaccination by a Novel Needleless Pyro-Drive Jet Injector.
Chinyang Chang, Jiao Sun, Hiroki Hayashi, Ayano Suzuki, Yuko Sakaguchi, Hiroshi Miyazaki, Tomoyuki Nishikawa, Hironori Nakagami, Kunihiko Yamashita, Yasufumi Kaneda
AAPS PharmSciTech Vol. 21 No. 1 p. 19-19 2019年12月9日 研究論文(学術雑誌)
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SF3B2-mediated RNA splicing drives human prostate cancer progression
Norihiko Kawamura, Keisuke Nimura, Kotaro Saga, Airi Ishibashi, Koji Kitamura, Hiromichi Nagano, Yusuke Yoshikawa, Kyoso Ishida, Norio Nonomura, Mitsuhiro Arisawa, Jun Luo, Yasufumi Kaneda
Cancer Research Vol. 79 No. 20 p. 5204-5217 2019年10月15日 研究論文(学術雑誌)
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去勢抵抗性前立腺癌に対するGEN0101の安全性及び抗腫瘍効果 第I相医師主導臨床試験
藤田 和利, 波多野 浩士, 加藤 大悟, 河嶋 厚成, 氏家 剛, 植村 元秀, 沖原 宏治, 浮村 理, 三木 恒治, 金田 安史, 野々村 祝夫
日本癌治療学会学術集会抄録集 Vol. 57回 p. O33-2 2019年10月
出版者・発行元:(一社)日本癌治療学会
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NANOG helps cancer cells escape NK cell attack by downregulating ICAM1 during tumorigenesis.
Saga K, Park J, Nimura K, Kawamura N, Ishibashi A, Nonomura N, Kaneda Y
Journal of experimental & clinical cancer research : CR Vol. 38 No. 1 2019年10月
出版者・発行元:Springer Science and Business Media LLC
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卵巣癌患者を対象とした患者由来不活化卵巣癌細胞と樹状細胞の融合細胞を用いたがんワクチン療法オープンラベル試験(An open-label trial of cancer vaccination by fusion cells from patient-derived ovarian cancer cells and dendritic cells)
石田 享相, 西川 智之, 清水 亜麻, 澤田 健二郎, 木村 正, 金田 安史
日本癌学会総会記事 Vol. 78回 p. P-1299 2019年9月
出版者・発行元:日本癌学会
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Cut-C: cleavage under tethered nuclease for conformational capture.
Takashi Shimbo, Machika Kawamura, Edward Wijaya, Eiichi Takaki, Yasufumi Kaneda, Katsuto Tamai
BMC genomics Vol. 20 No. 1 p. 614-614 2019年7月29日 研究論文(学術雑誌)
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Transcriptionally distinct mesenchymal stem/stromal cells circulate in fetus.
Aiko Okada, Takashi Shimbo, Masayuki Endo, Sayuri Iwai, Tomomi Kitayama, Yuya Ouchi, Ryoma Yamamoto, Eiichi Takaki, Sho Yamazaki, Mami Nishida, Xin Wang, Yasushi Kikuchi, Takuji Tomimatsu, Yasufumi Kaneda, Tadashi Kimura, Katsuto Tamai
Biochemical and biophysical research communications Vol. 512 No. 2 p. 326-330 2019年4月30日 研究論文(学術雑誌)
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Chromatin accessibility identifies diversity in mesenchymal stem cells from different tissue origins.
Ho YT, Shimbo T, Wijaya E, Ouchi Y, Takaki E, Yamamoto R, Kikuchi Y, Kaneda Y, Tamai K
2018年12月 研究論文(学術雑誌)
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RUNX1 positively regulates the ErbB2/HER2 signaling pathway through modulating SOS1 expression in gastric cancer cells
Yoshihide Mitsuda, Ken Morita, Gengo Kashiwazaki, Junichi Taniguchi, Toshikazu Bando, Moeka Obara, Masahiro Hirata, Tatsuki R. Kataoka, Manabu Muto, Yasufumi Kaneda, Tatsutoshi Nakahata, Pu Paul Liu, Souichi Adachi, Hiroshi Sugiyama, Yasuhiko Kamikubo
Scientific Reports Vol. 8 No. 1 2018年12月1日 研究論文(学術雑誌)
出版者・発行元:Nature Publishing Group
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Highly Selective Photodynamic Therapy with a Short Drug-Light Interval Using a Cytotoxic Photosensitizer Porphyrus Envelope for Drug-Resistant Prostate Cancer Cells
Youngsoon Hong, Mizuho Inai, Norihiro Honda, Hisanao Hazama, Manjusha A. Joshi, Hiroyuki Nakamura, Tomoyuki Nishikawa, Yasufumi Kaneda, Kunio Awazu
International Journal of Clinical Medicine 2018年1月 研究論文(学術雑誌)
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A New Approach to Castration-Resistant Prostate Cancer Using Inactivated Virus
Kazutoshi Fujita, Yasufumi Kaneda, Norio Nonomura
Hormone Therapy and Castration Resistance of Prostate Cancer 2018年
出版者・発行元:Springer Singapore
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Inactivated Sendai virus particle upregulates cancer cell expression of intercellular adhesion molecule-1 and enhances natural killer cell sensitivity on cancer cells
Simin Li, Tomoyuki Nishikawa, Yasufumi Kaneda
CANCER SCIENCE Vol. 108 No. 12 p. 2333-2341 2017年12月 研究論文(学術雑誌)
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Inactivated Sendai virus particle upregulates cancer cell expression of intercellular adhesion molecule-1 and enhances natural killer cell sensitivity on cancer cells
Simin Li, Tomoyuki Nishikawa, Yasufumi Kaneda
Cancer Science Vol. 108 No. 12 p. 2333-2341 2017年12月1日 研究論文(学術雑誌)
出版者・発行元:Blackwell Publishing Ltd
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Photodynamic therapy using a cytotoxic photosensitizer porphyrus envelope that targets the cell membrane
Mizuho Inai, Norihiro Honda, Hisanao Hazama, Sharmin Akter, Shinichiro Fuse, Hiroyuki Nakamura, Tomoyuki Nishikawa, Yasufumi Kaneda, Kunio Awazu
PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY Vol. 20 p. 238-245 2017年12月 研究論文(学術雑誌)
-
Physician-initiated first-in-human clinical study using a novel angiogenic peptide, AG30/5C, for patients with severe limb ulcers
Hironori Nakagami, Toshifumi Yamaoka, Misa Hayashi, Atsushi Tanemura, Yasushi Takeya, Hitomi Kurinami, Ken Sugimoto, Ayumi Nakamura, Kazunori Tomono, Katsuto Tamai, Ichiro Katayama, Hiromi Rakugi, Yasufumi Kaneda
GERIATRICS & GERONTOLOGY INTERNATIONAL Vol. 17 No. 11 p. 2150-2156 2017年11月 研究論文(学術雑誌)
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遺伝子スイッチ法を用いたRUNXクラスター制御がもたらす強力な抗癌作用(RUNX cluster regulation by GENE SWITCH triggers a profound tumor regression of diverse origins)
Morita Ken, Suzuki Kensho, Maeda Shintaro, Mitsuda Yoshihide, Tokushige Chieko, Kashiwazaki Gengo, Taniguchi Junichi, Maeda Rina, Noura Mina, Hirata Masahiro, Kataoka Tatsuki, Kiyos Hiroki, Tokumasu Mayu, Matsuo Hidemasa, Matsuo Akihiko, Tanaka Sunao, Okuno Yasushi, Muto Manabu, Naka Kazuhito, Ito Kosei, Kitamura Toshio, Kaneda Yasufumi, Liu Paul P., Bando Toshikazu, Sugiyama Hiroshi, Kamikubo Yasuhiko, Adachi Souichi
臨床血液 Vol. 58 No. 9 p. 1465-1465 2017年9月
出版者・発行元:(一社)日本血液学会-東京事務局
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Evaluation of therapeutic efficacy induced by a novel photosensitizer: talaporfin sodium-incorporated viral particle
Sharmin Akter, Sachiko Saito, Mizuho Inai, Norihiro Honda, Hisanao Hazama, Yoshiharu Okamoto, Yasufumi Kaneda, Kunio Awazu
2017年8月 研究論文(その他学術会議資料等)
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Phase I/II clinical trial to assess safety and efficacy of intratumoral and subcutaneous injection of HVJ-E in castration-resistant prostate cancer patients
K. Fujita, Y. Nakai, A. Kawashima, T. Ujike, A. Nagahara, T. Nakajima, T. Inoue, C. M. Lee, M. Uemura, Y. Miyagawa, Y. Kaneda, N. Nonomura
Cancer Gene Therapy Vol. 24 No. 7 p. 277-281 2017年7月1日 研究論文(学術雑誌)
出版者・発行元:Nature Publishing Group
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タラポルフィンナトリウム封入不活性化センダイウイルスを用いたPDTのin vivo坑腫瘍効果
稲井瑞穂, 斎藤祥子, 本多典広, 大崎 智弘, 間久直, 岡本芳晴, 金田安史, 粟津邦男
2017年7月 研究論文(その他学術会議資料等)
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複製能欠損ウイルス粒子とプロトポルフィリンIX脂質を用いたPDTにおける腫瘍選択性向上のための治療条件の検討
洪 暎淳, 稲井 瑞穂, 本多 典広, 間 久直, 布施 新一郎, 中村 浩之, 金田 安史, 粟津 邦男
2017年7月 研究論文(その他学術会議資料等)
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Genetic regulation of the RUNX transcription factor family has antitumor effects
Ken Morita, Kensho Suzuki, Shintaro Maeda, Akihiko Matsuo, Yoshihide Mitsuda, Chieko Tokushige, Gengo Kashiwazaki, Junichi Taniguchi, Rina Maeda, Mina Noura, Masahiro Hirata, Tatsuki Kataoka, Ayaka Yano, Yoshimi Yamada, Hiroki Kiyose, Mayu Tokumasu, Hidemasa Matsuo, Sunao Tanaka, Yasushi Okuno, Manabu Muto, Kazuhito Naka, Kosei Ito, Toshio Kitamura, Yasufumi Kaneda, Paul P. Liu, Toshikazu Bando, Souichi Adachi, Hiroshi Sugiyama, Yasuhiko Kamikubo
JOURNAL OF CLINICAL INVESTIGATION Vol. 127 No. 7 p. 2815-2828 2017年6月 研究論文(学術雑誌)
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Wolf-Hirschhorn Syndrome Candidate 1 Is Necessary for Correct Hematopoietic and B Cell Development
Elena Campos-Sanchez, Nerea Deleyto-Seldas, Veronica Dominguez, Enrique Carrillo-de-Santa-Pau, Kiyoe Ura, Pedro P. Rocha, JungHyun Kim, Arafat Aljoufi, Anna Esteve-Codina, Marc Dabad, Marta Gut, Holger Heyn, Yasufumi Kaneda, Keisuke Nimura, Jane A. Skok, Maria Luisa Martinez-Frias, Cesar Cobaleda
CELL REPORTS Vol. 19 No. 8 p. 1586-1601 2017年5月 研究論文(学術雑誌)
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Phase I/II clinical trial to assess safety and efficacy of intratumoral and subcutaneous injection of HVJ-E to castration resistant prostate cancer patients.
Fujita, K, Nakai, Y, Kawashima, A, Ujike, T, Nagahara, A, Uemura, M, Miyagawa Y, Lee, C-M, Inoue, T, Kaneda, Y, Nonomura, I
Cancer Gene Ther. 2017年5月 研究論文(学術雑誌)
-
Physician-initiated First-in-human Clinical Study using a Novel Angiogenic Peptide, AG30/5C, for Patients with Severe Limb Ulcers.
Nakagami, H, Yamaoka, T, Hayashi, M, Tanemura, A, Takeya Y, Kurinami, H, Sugimoto, K, Nakamura, A, Tomono, K, Tamai, K, Katayama, I, Rakugi, H, Kaneda, Y
Geriatrics & Gerontology International 2017年5月 研究論文(学術雑誌)
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Salmonella mediated the hemagglutinating virus of Japan-envelope transfer suppresses tumor growth
Che-Hsin Lee, Tomoyuki Nishikawa, Yasufumi Kaneda
ONCOTARGET Vol. 8 No. 21 p. 35048-35060 2017年5月 研究論文(学術雑誌)
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Wolf-Hirschhorn Syndrome Candidate 1 Is Necessary for Correct Hematopoietic and B Cell Development
Elena Campos-Sanchez, Nerea Deleyto-Seldas, Veronica Dominguez, Enrique Carrillo-de-Santa-Pau, Kiyoe Ura, Pedro P. Rocha, JungHyun Kim, Arafat Aljoufi, Anna Esteve-Codina, Marc Dabad, Marta Gut, Holger Heyn, Yasufumi Kaneda, Keisuke Nimura, Jane A. Skok, Maria Luisa Martinez-Frias, Cesar Cobaleda
CELL REPORTS Vol. 19 No. 8 p. 1586-1601 2017年5月 研究論文(学術雑誌)
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Glypican-1 targeted antibody-based therapy induces preclinical antitumor activity against esophageal squamous cell carcinoma
Emi Harada, Satoshi Serada, Minoru Fujimoto, Yusuke Takahashi, Tsuyoshi Takahashi, Hisashi Hara, Rie Nakatsuka, Takahito Sugase, Takahiko Nishigaki, Yurina Saito, Kosuke Hiramatsu, Satoshi Nojima, Risa Mitsuo, Tomoharu Ohkawara, Eiichi Morii, Masaki Mori, Yuichiro Doki, Yasufumi Kaneda, Tetsuji Naka
ONCOTARGET Vol. 8 No. 15 p. 24741-24752 2017年4月 研究論文(学術雑誌)
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Glypican-1 targeted antibody-based therapy induces preclinical antitumor activity against esophageal squamous cell carcinoma
Emi Harada, Satoshi Serada, Minoru Fujimoto, Yusuke Takahashi, Tsuyoshi Takahashi, Hisashi Hara, Rie Nakatsuka, Takahito Sugase, Takahiko Nishigaki, Yurina Saito, Kosuke Hiramatsu, Satoshi Nojima, Risa Mitsuo, Tomoharu Ohkawara, Eiichi Morii, Masaki Mori, Yuichiro Doki, Yasufumi Kaneda, Tetsuji Naka
ONCOTARGET Vol. 8 No. 15 p. 24741-24752 2017年4月 研究論文(学術雑誌)
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Development of a photosensitizing drug using replication-deficient virus particles and talaporfin sodium for photodynamic therapy of prostate cancer
Sachiko Saito, Mizuho Inai, Norihiro Honda, Hisanao Hazama, Yasufumi Kaneda, Kunio Awazu
2017年3月 研究論文(国際会議プロシーディングス)
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Development and application of DDS to activate anti-tumor immunity
Yasufumi Kaneda
Drug Delivery System Vol. 32 No. 3 p. 208-217 2017年 研究論文(学術雑誌)
出版者・発行元:Japan Society of Drug Delivery System
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複製能欠損ウイルス粒子をキャリアとした新規光感受性物質による光線力学治療の作用機序の検討
古山祐, 稲井瑞穂, 本多典広, 間久直, 布施新一郎, 中村浩之, 金田安史, 粟津邦男
2017年1月 研究論文(その他学術会議資料等)
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ホルモン拮抗ヒト前立腺癌細胞株PC-3における新規光感受性物質porphyrus envelope細胞内局在の検討
稲井瑞穂, 本多典広, 間久直, 中村浩之, 保田英洋, 西川智之, 金田安史, 粟津邦男
日本レーザー医学会誌 2017年1月 研究論文(学術雑誌)
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Salmonella mediated the hemagglutinating virus of Japan-envelope transfer suppresses tumor growth
Che-Hsin Lee, Tomoyuki Nishikawa, Yasufumi Kaneda
Oncotarget Vol. 8 No. 21 p. 35048-35060 2017年 研究論文(学術雑誌)
出版者・発行元:Impact Journals LLC
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Receptor for Advanced Glycation End Products-Mediated Signaling Impairs the Maintenance of Bone Marrow Mesenchymal Stromal Cells in Diabetic Model Mice
Eriko Aikawa, Ryo Fujita, Maiko Asai, Yasufumi Kaneda, Katsuto Tamai
STEM CELLS AND DEVELOPMENT Vol. 25 No. 22 p. 1721-1732 2016年11月 研究論文(学術雑誌)
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USAGE OF REPRICATION-DEFICIENT VIRAL PARTICLE FOR PHOTODYNAMIC THERAPY AGAINST PROSTATE CANCER ALLOWS HIGH CYTOTOXICITY THROUGH DIFFERENT PATHWAYS
Norihiro Honda, Mizuho Inai, Tasuku Furuyama, Young Soon Hong, Hisanao Hazama, Hiroyuki Nakamura, Hidehiro Yasuda, Tomoyuki Nishikawa, Yasufumi Kaneda, Kunio Awazu
2016年10月 研究論文(その他学術会議資料等)
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抗がん剤耐性前立腺がん細胞への迅速な薬剤輸送に向けた複製能欠損ウイルス粒子への光感受性物質の封入
洪 暎淳, 稲井 瑞穂, 古山 祐, 本多 典広, 間 久直, 布施 新一郎, 中村 浩之, 金田 安史, 粟津 邦男
2016年9月 研究論文(その他学術会議資料等)
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Virus-stimulated neutrophils in the tumor microenvironment enhance T cell-mediated anti-tumor immunity
Chin Yang Chang, Jiayu A. Tai, Sumin Li, Tomoyuki Nishikawa, Yasufumi Kaneda
ONCOTARGET Vol. 7 No. 27 p. 42195-42207 2016年7月 研究論文(学術雑誌)
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Regulation of alternative polyadenylation by Nkx2-5 and Xrn2 during mouse heart development.
Keisuke Nimura, Masamichi Yamamoto, Makiko Takeichi, Kotaro Saga, Katsuyoshi Takaoka, Norihiko Kawamura, Hirohisa Nitta, Hiromichi Nagano, Saki Ishino, Tatsuya Tanaka, Robert J Schwartz, Hiroyuki Aburatani, Yasufumi Kaneda
eLife Vol. 5 2016年6月22日 研究論文(学術雑誌)
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迅速な薬剤輸送に向けた複製能欠損センダイウイルス粒子への光感受性物質の封入条件の検討
洪 暎淳, 稲井 瑞穂, 本多 典広, 間 久直, 布施 新一郎, 中村 浩之, 金田 安史, 粟津 邦男
2016年6月 研究論文(その他学術会議資料等)
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タラポルフィンナトリウムを封入した複製能欠損ウイルスを用いた効果的なPDTの検討
斎藤 祥子, 稲井 瑞穂, 本多 典広, 間 久直, 金田 安史, 粟津 邦男
2016年6月 研究論文(その他学術会議資料等)
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複製能欠損ウイルス粒子とプロトポルフィリンIX脂質を利用したPDT過程のタイムラプス撮影による作用機序の検討
古山 祐, 稲井 瑞穂, 本多 典広, 間 久直, 布施 新一郎, 中村 浩之, 金田 安史, 粟津 邦男
2016年6月 研究論文(その他学術会議資料等)
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Cytoplasmic calcium increase via fusion with inactivated Sendai virus induces apoptosis in human multiple myeloma cells by downregulation of c-Myc oncogene
Yingzhe Jiang, Kotaro Saga, Yasuhide Miyamoto, Yasufumi Kaneda
ONCOTARGET Vol. 7 No. 24 p. 36034-36048 2016年6月 研究論文(学術雑誌)
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[Development of virosome-mediated cancer therapy].
Kaneda Y
Nihon yakurigaku zasshi. Folia pharmacologica Japonica Vol. 147 No. 6 p. 330-333 2016年6月
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Evolution of viral liposomes improvements and applications
Yasufumi Kaneda, Yoshinaga Saeki, Ryuichi Morishita
Drug Targeting Technology: Physical Chemical Biological Methods p. 249-260 2016年4月19日 論文集(書籍)内論文
出版者・発行元:CRC Press
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Platelet-cytokine Complex Suppresses Tumour Growth by Exploiting Intratumoural Thrombin-dependent Platelet Aggregation
Yu-Tung Li, Tomoyuki Nishikawa, Yasufumi Kaneda
SCIENTIFIC REPORTS Vol. 6 2016年4月 研究論文(学術雑誌)
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Effective photodynamic therapy in drug-resistant prostate cancer cells utilizing a non-viral antitumor vector (a secondary publication)
Masaya Yamauchi, Norihiro Honda, Hisanao Hazama, Shoji Tachikawa, Hiroyuki Nakamura, Yasufumi Kaneda, Kunio Awazu
Laser Therapy Vol. 25 No. 1 p. 55-62 2016年3月31日 研究論文(学術雑誌)
出版者・発行元:Japan Medical Laser Laboratory
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Elucidating the mechanisms of transcription regulation during heart development by next-generation sequencing
Keisuke Nimura, Yasufumi Kaneda
JOURNAL OF HUMAN GENETICS Vol. 61 No. 1 p. 5-12 2016年1月
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An RNA Molecule Derived From Sendai Virus DI Particles Induces Antitumor Immunity and Cancer Cell-selective Apoptosis
Li-Wen Liu, Tomoyuki Nishikawa, Yasufumi Kaneda
MOLECULAR THERAPY Vol. 24 No. 1 p. 135-145 2016年1月 研究論文(学術雑誌)
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Localization-dependent cell-killing effects of protoporphyrin (PPIX)-lipid micelles and liposomes in photodynamic therapy
Shoji Tachikawa, Shinichi Sato, Hisanao Hazama, Yasufumi Kaneda, Kunio Awazu, Hiroyuki Nakamura
BIOORGANIC & MEDICINAL CHEMISTRY Vol. 23 No. 24 p. 7578-7584 2015年12月 研究論文(学術雑誌)
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Cinnamtannin B-1 Promotes Migration of Mesenchymal Stem Cells and Accelerates Wound Healing in Mice
Kosuke Fujita, Katsunori Kuge, Noriyasu Ozawa, Shunya Sahara, Kaori Zaiki, Koichi Nakaoji, Kazuhiko Hamada, Yukiko Takenaka, Takao Tanahashi, Katsuto Tamai, Yasufumi Kaneda, Akito Maeda
PLOS ONE Vol. 10 No. 12 2015年12月 研究論文(学術雑誌)
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CRISPR/Cas9-mediated gene knockout of NANOG and NANOGP8 decreases the malignant potential of prostate cancer cells
Norihiko Kawamura, Keisuke Nimura, Hiromichi Nagano, Sohei Yamaguchi, Norio Nonomura, Yasufumi Kaneda
ONCOTARGET Vol. 6 No. 26 p. 22361-22374 2015年9月 研究論文(学術雑誌)
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ASGCT and JSGT Joint Position Statement on Human Genomic Editing
Theodore Friedmann, Erica C. Jonlin, Nancy M. P. King, Bruce E. Torbett, Nelson A. Wivel, Yasufumi Kaneda, Michel Sadelain
MOLECULAR THERAPY Vol. 23 No. 8 p. 1282-1284 2015年8月
-
Elucidating the mechanisms of transcription regulation during heart development by next-generation sequencing.
Nimura K, Kaneda Y
J. Human Genetics 2015年7月
-
Low alpha-synuclein levels in the blood are associated with insulin resistance
Gerardo Rodriguez-Araujo, Hironori Nakagami, Yoichi Takami, Tomohiro Katsuya, Hiroshi Akasaka, Shigeyuki Saitoh, Kazuaki Shimamoto, Ryuichi Morishita, Hiromi Rakugi, Yasufumi Kaneda
SCIENTIFIC REPORTS Vol. 5 2015年7月 研究論文(学術雑誌)
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Low alpha-synuclein levels in the blood are associated with insulin resistance
Gerardo Rodriguez-Araujo, Hironori Nakagami, Yoichi Takami, Tomohiro Katsuya, Hiroshi Akasaka, Shigeyuki Saitoh, Kazuaki Shimamoto, Ryuichi Morishita, Hiromi Rakugi, Yasufumi Kaneda
SCIENTIFIC REPORTS Vol. 5 2015年7月 研究論文(学術雑誌)
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CRISPR/Cas9-mediated gene knockout of NANOG1 and NANOGP8 leads to low malignant potential in prostate cancer.
Kawamura, N, Nimura, K, Nagano, H, Yamaguchi, S, Nonomura, N, Kaneda. Y
Oncotarget 2015年6月 研究論文(学術雑誌)
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Systemic high-mobility group box 1 administration suppresses skin inflammation by inducing an accumulation of PDGFRα+ mesenchymal cells from bone marrow
Eriko Aikawa, Ryo Fujita, Yasushi Kikuchi, Yasufumi Kaneda, Katsuto Tamai
Scientific Reports Vol. 5 2015年6月 研究論文(学術雑誌)
-
Systemic high-mobility group box 1 administration suppresses skin inflammation by inducing an accumulation of PDGFRα(+) mesenchymal cells from bone marrow.
Aikawa E, Fujita R, Kikuchi Y, Kaneda Y, Tamai K
Scientific reports Vol. 5 2015年6月 研究論文(学術雑誌)
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抗腫瘍効果を持つ非ウィルスベクターを用いた薬剤耐性前立腺がん細胞に対する高効率な光線力学療法
山内将哉, 本多典広, 間久直, 立川将士, 中村浩之, 金田安史, 粟津邦男
日本レーザー医学会誌 Vol. 36 No. 1 p. 18-24 2015年4月 研究論文(学術雑誌)
出版者・発行元:下野印刷
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Endogenous Mesenchymal Stromal Cells in Bone Marrow Are Required to Preserve Muscle Function in mdx Mice
Ryo Fujita, Katsuto Tamai, Eriko Aikawa, Keisuke Nimura, Saki Ishino, Yasushi Kikuchi, Yasufumi Kaneda
STEM CELLS Vol. 33 No. 3 p. 962-975 2015年3月 研究論文(学術雑誌)
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Endogenous Mesenchymal Stromal Cells in Bone Marrow Are Required to Preserve Muscle Function in mdx Mice
Ryo Fujita, Katsuto Tamai, Eriko Aikawa, Keisuke Nimura, Saki Ishino, Yasushi Kikuchi, Yasufumi Kaneda
STEM CELLS Vol. 33 No. 3 p. 962-975 2015年3月 研究論文(学術雑誌)
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Transplanted bone marrow-derived circulating PDGFR+ cells restore type VII collagen in recessive dystrophic epidermolysis bullosa mouse skin graft.
IInuma S, Aikawa E, Tamai K, Fujita R, Kikuchi Y, Chino T, Kikuta J, McGrath J, Uitto J, Ishi M, Iizuka H, Kaneda Y
J. Immunology Vol. 194 No. 4 p. 1996-2003 2015年2月 研究論文(学術雑誌)
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Transplanted bone marrow-derived circulating PDGFRα+ cells restore type VII collagen in recessive dystrophic epidermolysis bullosa mouse skin graft.
Iinuma S, Aikawa E, Tamai K, Fujita R, Kikuchi Y, Chino T, Kikuta J, McGrath JA, Uitto J, Ishii M, Iizuka H, Kaneda Y
Journal of immunology (Baltimore, Md. : 1950) Vol. 194 No. 4 p. 1996-2003 2015年2月 研究論文(学術雑誌)
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Photodynamic therapy using hemagglutinating virus of Japan envelope (HVJ-E): a novel therapeutic approach for the treatment of hormone antagonistic prostate cancer
Mizuho Inai, Masaya Yamauchi, Norihiro Honda, Hisanao Hazama, Shoji Tachikawa, Hiroyuki Nakamura, Tomoki Nishida, Hidehiro Yasuda, Yasufumi Kaneda, Kunio Awazu
OPTICAL METHODS FOR TUMOR TREATMENT AND DETECTION: MECHANISMS AND TECHNIQUES IN PHOTODYNAMIC THERAPY XXIV Vol. 9308 2015年 研究論文(国際会議プロシーディングス)
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Oncolytic Sendai virus-based virotherapy for cancer: recent advances.
Saga K, Kaneda Y
Oncolytic virotherapy Vol. 4 p. 141-147 2015年
出版者・発行元:Informa UK Limited
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筋ジストロフィーにおける内在性骨髄間葉系細胞の生理的意義
藤田 諒, 相川 恵梨子, 玉井 克人, 金田 安史
体力科学 Vol. 63 No. 6 p. 555-555 2014年12月
出版者・発行元:(一社)日本体力医学会
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Systemic Administration of Platelets Incorporating Inactivated Sendai Virus Eradicates Melanoma in Mice
Tomoyuki Nishikawa, Li Yu Tung, Yasufumi Kaneda
MOLECULAR THERAPY Vol. 22 No. 12 p. 2046-2055 2014年12月 研究論文(学術雑誌)
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Systemic Administration of Platelets Incorporating Inactivated Sendai Virus Eradicates Melanoma in Mice
Tomoyuki Nishikawa, Li Yu Tung, Yasufumi Kaneda
MOLECULAR THERAPY Vol. 22 No. 12 p. 2046-2055 2014年12月 研究論文(学術雑誌)
-
Histone H3 Lysine 36 Methyltransferase Whsc1 Promotes the Association of Runx2 and p300 in the Activation of Bone-Related Genes
Yu Fei Lee, Keisuke Nimura, Wan Ning Lo, Kotaro Saga, Yasufumi Kaneda
PLOS ONE Vol. 9 No. 9 2014年9月 研究論文(学術雑誌)
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Development of Laser Ionization Techniques for Evaluation of the Effect of Cancer Drugs Using Imaging Mass Spectrometry
Hiroki Kannen, Hisanao Hazama, Yasufumi Kaneda, Tatsuya Fujino, Kunio Awazu
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Vol. 15 No. 7 p. 11234-11244 2014年7月 研究論文(学術雑誌)
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不活性センダイウイルス粒子HVJ-Eはcaspase-8欠損神経芽腫に対してnecroptosisを誘導する
野村 元成, 福澤 正洋, 金田 安史
日本小児外科学会雑誌 Vol. 50 No. 3 p. 483-483 2014年4月
出版者・発行元:(一社)日本小児外科学会
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神経芽腫におけるCaM kinase II活性化を介した新たな細胞死誘導機構の解明
野村 元成, 福澤 正洋, 金田 安史
日本外科学会雑誌 Vol. 115 No. 臨増2 p. 776-776 2014年3月
出版者・発行元:(一社)日本外科学会
-
A novel photodynamic therapy for drug-resistant prostate cancer cells using porphyrus envelope as a novel photosensitizer
Masaya Yamauchi, Norihiro Honda, Hisanao Hazama, Shoji Tachikawa, Hiroyuki Nakamura, Yasufumi Kaneda, Kunio Awazu
PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY Vol. 11 No. 1 p. 48-54 2014年3月 研究論文(学術雑誌)
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Novel Anti-Microbial Peptide SR-0379 Accelerates Wound Healing via the PI3 Kinase/Akt/mTOR Pathway
Hideki Tomioka, Hironori Nakagami, Akiko Tenma, Yoshimi Saito, Toshihiro Kaga, Toshihide Kanamori, Nao Tamura, Kazunori Tomono, Yasufumi Kaneda, Ryuichi Morishita
PLOS ONE Vol. 9 No. 3 2014年3月 研究論文(学術雑誌)
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Mallotus philippinensis bark extracts promote preferential migration of mesenchymal stem cells and improve wound healing in mice
Tadashi Furumoto, Noriyasu Ozawa, Yuta Inami, Misaki Toyoshima, Kosuke Fujita, Kaori Zaiki, Shunya Sahara, Mariko Akita, Keiko Kitamura, Koichi Nakaoji, Kazuhiko Hamada, Katsuto Tamai, Yasufumi Kaneda, Akito Maeda
PHYTOMEDICINE Vol. 21 No. 3 p. 247-253 2014年2月 研究論文(学術雑誌)
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Accumulation of Cytosolic Calcium Induces Necroptotic Cell Death in Human Neuroblastoma
Motonari Nomura, Ayumi Ueno, Kotaro Saga, Masahiro Fukuzawa, Yasufumi Kaneda
CANCER RESEARCH Vol. 74 No. 4 p. 1056-1066 2014年2月 研究論文(学術雑誌)
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Development of LC-MS/MS quantification of the novel antimicrobial peptide, SR-0379, and its pharmacokinetics in rats
Hideki Tomioka, Hironori Nakagami, Tomokazu Sano, Kazuaki Takafuji, Seiji Takashima, Yasufumi Kaneda, Ryuichi Morishita
Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry Vol. 14 No. 1 p. 26-31 2014年 研究論文(学術雑誌)
出版者・発行元:Bentham Science Publishers B.V.
-
Virosome presents multimodel cancer therapy without viral replication.
Saga K, Kaneda Y
Biomedical Research Int. 2013年12月
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トランスレーショナル研究と新規治療 皮膚と骨髄のクロストーク 間葉系幹細胞の体内移動メカニズム解明と治療への応用
玉井 克人, 菊池 康, 相川 恵梨子, 金田 安史, 片山 一郎
神経免疫学 Vol. 18 No. 1 p. 56-56 2013年11月
出版者・発行元:日本神経免疫学会
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神経芽腫におけるCa2+/カルモデュリン依存性プロテインキナーゼII活性化を介した新たな細胞死誘導機構
野村 元成, 福澤 正洋, 金田 安史
日本小児血液・がん学会学術集会・日本小児がん看護学会・公益財団法人がんの子どもを守る会公開シンポジウムプログラム総会号 Vol. 55回・11回・18回 p. 229-229 2013年11月
出版者・発行元:(NPO)日本小児血液・がん学会・(NPO)日本小児がん看護学会・(公財)がんの子供を守る会
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トランスレーショナル研究と新規治療 皮膚と骨髄のクロストーク 間葉系幹細胞の体内移動メカニズム解明と治療への応用
玉井 克人, 菊池 康, 相川 恵梨子, 金田 安史, 片山 一郎
日本臨床免疫学会会誌 Vol. 36 No. 5 p. 299-299 2013年10月
出版者・発行元:日本臨床免疫学会
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Anti-tumor effects of inactivated Sendai virus particles with an IL-2 gene on angiosarcoma
Yuki Takehara, Takahiro Satoh, Aya Nishizawa, Kazumi Saeki, Masataka Nakamura, Mikio Masuzawa, Yasufumi Kaneda, Ichiro Katayama, Hiroo Yokozeki
CLINICAL IMMUNOLOGY Vol. 149 No. 1 p. 1-10 2013年10月 研究論文(学術雑誌)
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Residual Prostate Cancer Cells after Docetaxel Therapy Increase the Tumorigenic Potential via Constitutive Signaling of CXCR4, ERK1/2 and c-Myc
Koji Hatano, Souhei Yamaguchi, Keisuke Nimura, Kouki Murakami, Akira Nagahara, Kazutoshi Fujita, Motohide Uemura, Yasutomo Nakai, Mutsumi Tsuchiya, Masashi Nakayama, Norio Nonomura, Yasufumi Kaneda
MOLECULAR CANCER RESEARCH Vol. 11 No. 9 p. 1088-1100 2013年9月 研究論文(学術雑誌)
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再生医療と新規材料 骨髄間葉系幹細胞の動員による組織再生の分子機構
金田 安史, 玉井 克人
日本DDS学会学術集会プログラム予稿集 Vol. 29回 p. 75-75 2013年6月
出版者・発行元:日本DDS学会
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Occurrence of free deaminoneuraminic acid (KDN)-containing complex-type N-glycans in human prostate cancers
Masahiko Yabu, Hiroaki Korekane, Koji Hatano, Yasufumi Kaneda, Norio Nonomura, Chihiro Sato, Ken Kitajima, Yasuhide Miyamoto
GLYCOBIOLOGY Vol. 23 No. 6 p. 634-642 2013年6月 研究論文(学術雑誌)
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不活化センダイウイルス粒子HVJ-Eによる新たな神経芽腫細胞死誘導機構の解明
野村 元成, 金田 安史
日本小児外科学会雑誌 Vol. 49 No. 3 p. 689-689 2013年5月
出版者・発行元:(一社)日本小児外科学会
-
The RIG-I/MAVS signaling pathway in cancer cell-selective apoptosis
Yasufumi Kaneda
OncoImmunology Vol. 2 No. 4 2013年4月 研究論文(学術雑誌)
-
【臓器円環による生体恒常性のダイナミクス 神経・免疫・循環・内分泌系の連関による維持、ライフステージに応じた変容と破綻】(第1章)組織幹細胞における恒常性維持・変容・破綻 骨髄由来幹細胞による組織修復機構
金田 安史, 玉井 克人
実験医学 Vol. 31 No. 5 p. 655-661 2013年3月
出版者・発行元:(株)羊土社
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Future directions for gene therapy
Yasufumi Kaneda
Gene Therapy: Technologies and Applications 2013年3月1日 論文集(書籍)内論文
出版者・発行元:Future Medicine Ltd.
-
Alpha-synuclein elicits glucose uptake and utilization in adipocytes through the Gab1/PI3K/Akt transduction pathway
Gerardo Rodriguez-Araujo, Hironori Nakagami, Hiroki Hayashi, Masaki Mori, Tetsuya Shiuchi, Yasuhiko Minokoshi, Yoshikazu Nakaoka, Yoichi Takami, Issei Komuro, Ryuichi Morishita, Yasufumi Kaneda
Cellular and Molecular Life Sciences Vol. 70 No. 6 p. 1123-1133 2013年3月 研究論文(学術雑誌)
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13-Cis retinoic acid can enhance the antitumor activity of non-replicating Sendai virus particle against neuroblastoma
Motonari Nomura, Takashi Shimbo, Yasuhide Miyamoto, Masahiro Fukuzawa, Yasufumi Kaneda
CANCER SCIENCE Vol. 104 No. 2 p. 238-244 2013年2月 研究論文(学術雑誌)
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Systemic administration of a novel immune-stimulatory pseudovirion suppresses lung metastatic melanoma by regionally enhancing IFN-γ production.
Saga K, Tamai K, Yamazaki T, Kaneda Y
Clinical cancer research : an official journal of the American Association for Cancer Research Vol. 19 No. 3 p. 668-679 2013年2月 研究論文(学術雑誌)
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The Transcription Factors Tbx18 and Wt1 Control the Epicardial Epithelial-Mesenchymal Transition through Bi-Directional Regulation of Slug in Murine Primary Epicardial Cells
Makiko Takeichi, Keisuke Nimura, Masaki Mori, Hironori Nakagami, Yasufumi Kaneda
PLOS ONE Vol. 8 No. 2 2013年2月 研究論文(学術雑誌)
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Lymphedema and Therapeutic Lymphangiogenesis
Yukihiro Saito, Hironori Nakagami, Yasufumi Kaneda, Ryuichi Morishita
BIOMED RESEARCH INTERNATIONAL Vol. 2013 2013年
-
Virosome Presents Multimodel Cancer Therapy without Viral Replication
Kotaro Saga, Yasufumi Kaneda
BIOMED RESEARCH INTERNATIONAL Vol. 2013 2013年
-
The study of novel DNA vaccines against tuberculosis: Induction of pathogen-specific CTL in the mouse and monkey models of tuberculosis.
Okada M, Kita Y, Nakajima T, Hashimoto S, Nakatani H, Nishimatsu S, Nishida Y, Kanamaru N, Kaneda Y, Takamori Y, McMurray D, Tan EV, Cang ML, Saunderson P, Dela Cruz EC
Human vaccines & immunotherapeutics Vol. 9 2012年12月
出版者・発行元:3
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不活化センダイウイルス粒子HVJ-Eの神経芽腫に対する抗腫瘍効果は13cisレチノイン酸により増強される
野村 元成, 新保 敬史, 宮本 泰豪, 金田 安史, 福澤 正洋
日本小児血液・がん学会学術集会・日本小児がん看護学会・公益財団法人がんの子どもを守る会公開シンポジウムプログラム総会号 Vol. 54回・10回・17回 p. 292-292 2012年11月
出版者・発行元:(NPO)日本小児血液・がん学会・(NPO)日本小児がん看護学会・(公財)がんの子供を守る会
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TRAIL and Noxa Are Selectively Upregulated in Prostate Cancer Cells Downstream of the RIG-I/MAVS Signaling Pathway by Nonreplicating Sendai Virus Particles
Taeko Matsushima-Miyagi, Koji Hatano, Motonari Nomura, Liu Li-Wen, Tomoyuki Nishikawa, Kotaro Saga, Takashi Shimbo, Yasufumi Kaneda
CLINICAL CANCER RESEARCH Vol. 18 No. 22 p. 6271-6283 2012年11月 研究論文(学術雑誌)
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Long-Term Follow-Up Evaluation of Results From Clinical Trial Using Hepatocyte Growth Factor Gene to Treat Severe Peripheral Arterial Disease
Hirofumi Makino, Motokuni Aoki, Naotaka Hashiya, Keita Yamasaki, Junya Azuma, Yoshiki Sawa, Yasufumi Kaneda, Toshio Ogihara, Ryuichi Morishita
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY Vol. 32 No. 10 p. 2503-+ 2012年10月 研究論文(学術雑誌)
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損傷組織の放出するHMGB1は骨髄間葉系幹細胞を動員して損傷組織の再生を誘導する(Injured tissues release HMGB1 to recruit bone marrow mesenchymal stem cells for inducing regeneration of the injury)
玉井 克人, 菊池 康, 飯沼 晋, 金田 安史
日本癌学会総会記事 Vol. 71回 p. 292-292 2012年8月
出版者・発行元:日本癌学会
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不活化センダイウイルス粒子(HVJ-E)は神経芽腫細胞株SK-N-SHに対してRIP1を介したネクロプトーシスを誘導する(Inactivated Sendai virus particle (HVJ-E) causes RIP1-mediated necroptosis in neuroblastoma cell line SK-N-SH)
野村 元成, 新保 敬史, 宮本 泰豪, 福澤 正洋, 金田 安史
日本癌学会総会記事 Vol. 71回 p. 526-526 2012年8月
出版者・発行元:日本癌学会
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【最新疾患モデルと病態解明、創薬応用研究、細胞医薬創製研究の最前線 最新疾患モデル動物、ヒト化マウス、モデル細胞、ES・iPS細胞を利用した病態解明から創薬まで】(第2章)各種病態モデルと創薬研究 皮膚・炎症性疾患 生体内骨髄間葉系幹/前駆細胞動員因子を利用した体内再生誘導医薬開発の展望
玉井 克人, 金田 安史
遺伝子医学MOOK No. 22 p. 207-212 2012年7月
出版者・発行元:(株)メディカルドゥ
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The combination of chemotherapy with HVJ-E containing Rad51 siRNA elicited diverse anti-tumor effects and synergistically suppressed melanoma
E. Kiyohara, K. Tamai, I. Katayama, Y. Kaneda
GENE THERAPY Vol. 19 No. 7 p. 734-741 2012年7月 研究論文(学術雑誌)
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Modification of a novel angiogenic peptide, AG30, for the development of novel therapeutic agents
Hironori Nakagami, Tomoyuki Nishikawa, Nao Tamura, Akito Maeda, Hajime Hibino, Masayoshi Mochizuki, Takashi Shimosato, Toshinori Moriya, Ryuichi Morishita, Katsuto Tamai, Kazunori Tomono, Yasufumi Kaneda
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE Vol. 16 No. 7 p. 1629-1639 2012年7月 研究論文(学術雑誌)
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In vitro investigation of efficient photodynamic therapy using a nonviral vector; hemagglutinating virus of Japan envelope
Makoto Sakai, Naohiro Fujimoto, Katsunori Ishii, Hiroyuki Nakamura, Yasufumi Kaneda, Kunio Awazu
JOURNAL OF BIOMEDICAL OPTICS Vol. 17 No. 7 2012年7月 研究論文(学術雑誌)
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In vitro investigation of efficient photodynamic therapy using a nonviral vector; hemagglutinating virus of Japan envelope
Makoto Sakai, Naohiro Fujimoto, Katsunori Ishii, Hiroyuki Nakamura, Yasufumi Kaneda, Kunio Awazu
JOURNAL OF BIOMEDICAL OPTICS Vol. 17 No. 7 2012年7月 研究論文(学術雑誌)
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In vitro investigation of efficient photodynamic therapy using a nonviral vector; hemagglutinating virus of Japan envelope
Makoto Sakai, Naohiro Fujimoto, Katsunori Ishii, Hiroyuki Nakamura, Yasufumi Kaneda, Kunio Awazu
JOURNAL OF BIOMEDICAL OPTICS Vol. 17 No. 7 2012年7月 研究論文(学術雑誌)
-
Virosome: A novel vector to enable multi-modal strategies for cancer therapy
Yasufumi Kaneda
ADVANCED DRUG DELIVERY REVIEWS Vol. 64 No. 8 p. 730-738 2012年6月
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HIG1, a novel regulator of mitochondrial γ-secretase, maintains normal mitochondrial function.
Hayashi H, Nakagami H, Takeichi M, Shimamura M, Koibuchi N, Oiki E, Sato N, Koriyama H, Mori M, Gerardo Araujo R, Maeda A, Morishita R, Tamai K, Kaneda Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Vol. 26 No. 6 p. 2306-2317 2012年6月 研究論文(学術雑誌)
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Therapeutic strategies for controlling the metastasis and recurrence of cancers: contribution of drug delivery technologies Preface
Yasufumi Kaneda
ADVANCED DRUG DELIVERY REVIEWS Vol. 64 No. 8 p. 707-709 2012年6月
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神経芽腫に対する不活化ウイルス粒子HVJ-Eの抗腫瘍効果の検討
野村 元成, 新保 敬史, 宮本 泰豪, 金田 安史, 福澤 正洋
日本小児外科学会雑誌 Vol. 48 No. 3 p. 469-469 2012年5月
出版者・発行元:(一社)日本小児外科学会
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パーキンソン病関連分子αシヌクレインの老化関連疾患における新規機能 メタボリック症候群及び血管内皮機能への関与
鷹見 洋一, 大石 充, 中神 啓徳, 神出 計, 山本 浩一, 金田 安史, 楽木 宏実
日本高血圧学会臨床高血圧フォーラムプログラム・抄録集 Vol. 1回 p. 139-139 2012年4月
出版者・発行元:(NPO)日本高血圧学会
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表皮水疱症に対する骨髄間葉系幹細胞移植治療の可能性
玉井 克人, 知野 剛直, 飯沼 晋, 梅垣 知子, 金田 安史, 片山 一朗, 中野 創, 澤村 大輔, 橋本 功, 北島 康雄, 飯塚 一, 白方 祐司, 橋本 公二
西日本皮膚科 Vol. 74 No. 2 p. 206-206 2012年4月
出版者・発行元:日本皮膚科学会-西部支部
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Essential Role for miR-196a in Brown Adipogenesis of White Fat Progenitor Cells
Masaki Mori, Hironori Nakagami, Gerardo Rodriguez-Araujo, Keisuke Nimura, Yasufumi Kaneda
PLOS BIOLOGY Vol. 10 No. 4 2012年4月 研究論文(学術雑誌)
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Essential role for miR-196a in brown adipogenesis of white fat progenitor cells
Masaki Mori, Hironori Nakagami, Gerardo Rodriguez-Araujo, Keisuke Nimura, Yasufumi Kaneda
PLoS Biology Vol. 10 No. 4 2012年4月 研究論文(学術雑誌)
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Androgen-Regulated Transcriptional Control of Sialyltransferases in Prostate Cancer Cells
Koji Hatano, Yasuhide Miyamoto, Masaki Mori, Keisuke Nimura, Yasutomo Nakai, Norio Nonomura, Yasufumi Kaneda
PLOS ONE Vol. 7 No. 2 2012年2月 研究論文(学術雑誌)
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Tissue regeneration by recruitment of stem cells to injured tissues
Yasufumi Kaneda
Drug Delivery System Vol. 27 No. 4 p. 246-256 2012年 研究論文(学術雑誌)
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【組織・臓器を修復するStem Cell】骨髄間葉系幹細胞に備わる組織損傷シグナルへの応答機構
玉井 克人, 金田 安史
実験医学 Vol. 29 No. 19 p. 3085-3090 2011年12月
出版者・発行元:(株)羊土社
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Development of Liposomes and Pseudovirions with Fusion Activity for Efficient Gene Delivery
Yasufumi Kaneda
CURRENT GENE THERAPY Vol. 11 No. 6 p. 434-441 2011年12月
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Expression of gangliosides, GD1a, and sialyl paragloboside is regulated by NF-κB-dependent transcriptional control of α2,3-sialyltransferase I, II, and VI in human castration-resistant prostate cancer cells.
Hatano K, Miyamoto Y, Nonomura N, Kaneda Y
International journal of cancer Vol. 129 No. 8 p. 1838-1847 2011年10月 研究論文(学術雑誌)
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Critical Roles of Cold Shock Domain Protein A as an Endogenous Angiogenesis Inhibitor in Skeletal Muscle
Yukihiro Saito, Hironori Nakagami, Nobuyoshi Azuma, Satoshi Hirata, Fumihiro Sanada, Yoshiaki Taniyama, Ryuichi Morishita, Yasufumi Kaneda, Tadahiro Sasajima
ANTIOXIDANTS & REDOX SIGNALING Vol. 15 No. 8 p. 2109-2120 2011年10月 研究論文(学術雑誌)
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HVJ liposomes and HVJ envelope vectors.
Kaneda Y
Cold Spring Harbor protocols Vol. 2011 No. 10 p. 1281-1289 2011年10月
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非ウイルスベクターHVJ-Eを用いた高効率光線力学療法の開発
藤本尚弘, 酒井真理, 石井克典, M.E. El-Zaria, H.S. Ban, 中村浩之, 金田安史, 粟津邦男
2011年7月 研究論文(その他学術会議資料等)
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Methyl-beta cyclodextrin alters the production and infectivity of Sendai virus
Hiroshi Fujita, Katsuto Tamai, Masako Kawachi, Kotaro Saga, Takashi Shimbo, Takehiko Yamazaki, Yasufumi Kaneda
ARCHIVES OF VIROLOGY Vol. 156 No. 6 p. 995-1005 2011年6月 研究論文(学術雑誌)
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In vitro investigation for high efficiency PPIX-PDT with nonviral vector; HVJ-E
K. Awazu, N. Fujimoto, M. Sakai, K. Ishii, M.E. El-Zaria, H.S. Ban, H. Nakamura, Y. Kaneda
2011年5月
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Immunogene therapy using immunomodulating HVJ-E vector augments anti-tumor effects in murine malignant glioma
Masahide Matsuda, Keisuke Nimura, Takashi Shimbo, Toshimitsu Hamasaki, Tetsuya Yamamoto, Akira Matsumura, Yasufumi Kaneda
JOURNAL OF NEURO-ONCOLOGY Vol. 103 No. 1 p. 19-31 2011年5月 研究論文(学術雑誌)
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Photodynamic therapywith high PPIX uptake using a nonviral vector DDS
K. Awazu, K. Ishii, N. Fujimoto, M. Sakai, M.E. El-Zaria, H.S. Ban, H. Nakamura, Y. Kaneda
2011年4月 研究論文(その他学術会議資料等)
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PDGFR alpha-positive cells in bone marrow are mobilized by high mobility group box 1 (HMGB1) to regenerate injured epithelia
Katsuto Tamai, Takehiko Yamazaki, Takenao Chino, Masaru Ishii, Satoru Otsuru, Yasushi Kikuchi, Shin Iinuma, Kotaro Saga, Keisuke Nimura, Takashi Shimbo, Noriko Umegaki, Ichiro Katayama, Jun-ichi Miyazaki, Junji Takeda, John A. McGrath, Jouni Uitto, Yasufumi Kaneda
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA Vol. 108 No. 16 p. 6609-6614 2011年4月 研究論文(学術雑誌)
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骨髄細胞による表皮恒常性維持機構
玉井 克人, 知野 剛直, 飯沼 晋, 金田 安史, 梅垣 知子, 片山 一朗
角化症研究会記録集 Vol. 25 p. 38-40 2011年3月
出版者・発行元:角化症研究会事務局
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Phase I/IIa Clinical Trial of Therapeutic Angiogenesis Using Hepatocyte Growth Factor Gene Transfer to Treat Critical Limb Ischemia
Ryuichi Morishita, Hirofumi Makino, Motokuni Aoki, Naotaka Hashiya, Keita Yamasaki, Junya Azuma, Yoshiaki Taniyama, Yoshiki Sawa, Yasufumi Kaneda, Toshio Ogihara
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY Vol. 31 No. 3 p. 713-720 2011年3月 研究論文(学術雑誌)
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DNA methyltransferase 3b preferentially associates with condensed chromatin
Katsunobu Kashiwagi, Keisuke Nimura, Kiyoe Ura, Yasufumi Kaneda
NUCLEIC ACIDS RESEARCH Vol. 39 No. 3 p. 874-888 2011年2月 研究論文(学術雑誌)
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A Novel Therapeutic and Prophylactic Vaccine against Tuberculosis Using the Cynomolgus Monkey Model and Mouse Model
M. Okada, Y. Kita, T. Nakajima, N. Kanamaru, Y. Kaneda, P. Saunderson, E. Tan, N. McMurray D
4TH VACCINE AND ISV ANNUAL GLOBAL CONGRESS Vol. 4 2011年 研究論文(国際会議プロシーディングス)
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Cationized gelatin-HVJ envelope with sodium borocaptate improved the BNCT efficacy for liver tumors in vivo
Hitoshi Fujii, Akifumi Matsuyama, Hiroshi Komoda, Masao Sasai, Minoru Suzuki, Tomoyuki Asano, Yuichiro Doki, Mitsunori Kirihata, Koji Ono, Yasuhiko Tabata, Yasufumi Kaneda, Yoshiki Sawa, Chun Man Lee
RADIATION ONCOLOGY Vol. 6 2011年1月 研究論文(学術雑誌)
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Development of therapeutic and prophylactic vaccine against tuberculosis using monkey and transgenic mice models
Yoko Kita, Masaji Okada, Toshihiro Nakajima, Noriko Kanamaru, Satomi Hashimoto, Tetsuji Nagasawa, Yasufumi Kaneda, Shigeto Yoshida, Yasuko Nishida, Hitoshi Nakatani, Kyoko Takao, Chie Kishigami, Shiho Nishimatsu, Yuki Sekine, Yasushi Takamori, David N. McMurray, E. C. De la Cruz, E. V. Tan, R. M. Abalos, J. A. Burgos, Paul Saunderson, Mitsunori Sakatani
HUMAN VACCINES Vol. 7 p. 108-114 2011年1月 研究論文(学術雑誌)
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Novel Prophylactic Vaccine Using a Prime-Boost Method and Hemagglutinating Virus of Japan-Envelope against Tuberculosis
Masaji Okada, Yoko Kita, Toshihiro Nakajima, Noriko Kanamaru, Satomi Hashimoto, Tetsuji Nagasawa, Yasufumi Kaneda, Shigeto Yoshida, Yasuko Nishida, Hitoshi Nakatani, Kyoko Takao, Chie Kishigami, Shiho Nishimatsu, Yuki Sekine, Yoshikazu Inoue, David N. McMurray, Andmitsunori Sakatani
CLINICAL & DEVELOPMENTAL IMMUNOLOGY Vol. 2011 2011年 研究論文(学術雑誌)
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Novel therapeutic vaccine Granulysin and new DNA vaccine against tuberculosis
Masaji Okada, Yoko Kita, Toshihiro Nakajima, Noriko Kanamaru, Satomi Hashimoto, Tetsuji Nagasawa, Yasufumi Kaneda, Shigeto Yoshida, Yasuko Nishida, Hitoshi Nakatani, Kyoko Takao, Chie Kishigami, Shiho Nishimatsu, Yuki Sekine, Yoshikazu Inoue, Makoto Matsumoto, David N. McMurray, E. C. Dela Cruz, E. V. Tan, R. M. Abalos, J. A. Burgos, Paul Saunderson, Mitsunori Sakatani
HUMAN VACCINES Vol. 7 p. 60-67 2011年1月 研究論文(学術雑誌)
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EG5 siRNA COMBINED WITH HVJ ENVELOPE SYNERGISTICALLY INDUCED CELL DEATH IN GLIOBLASTOMA
Matsuda, Masahide, Yamamoto, Tetsuya, Matsumura, Akira, Kaneda, Yasufumi
JOURNAL OF GENE MEDICINE Vol. 12 No. 12 p. 1043-1043 2010年12月 研究論文(学術雑誌)
出版者・発行元:JOHN WILEY & SONS LTD
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Histone methyltransferases: regulation of transcription and contribution to human disease
Keisuke Nimura, Kiyoe Ura, Yasufumi Kaneda
JOURNAL OF MOLECULAR MEDICINE-JMM Vol. 88 No. 12 p. 1213-1220 2010年12月
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A non-replicating oncolytic vector as a novel therapeutic tool against cancer
Yasufumi Kaneda
BMB REPORTS Vol. 43 No. 12 p. 773-780 2010年12月
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非ウイルスベクターHVJ-Eを用いた高効率PPIX-PDTの培養がん細胞での検討
藤本尚弘, 酒井真理, 石井克典, E. El-Zaria Mohamed, 潘鉉承, 中村浩之, 金田安史, 粟津邦男
2010年11月 研究論文(その他学術会議資料等)
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Cold shock domain protein A (CSDA) overexpression inhibits tumor growth and lymph node metastasis in a mouse model of squamous cell carcinoma
Goichi Matsumoto, Nobuyuki Yajima, Hiroyuki Saito, Hironori Nakagami, Yasushi Omi, Ushaku Lee, Yasufumi Kaneda
CLINICAL & EXPERIMENTAL METASTASIS Vol. 27 No. 7 p. 539-547 2010年10月 研究論文(学術雑誌)
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Update on non-viral delivery methods for cancer therapy: possibilities of a drug delivery system with anticancer activities beyond delivery as a new therapeutic tool
Yasufumi Kaneda
EXPERT OPINION ON DRUG DELIVERY Vol. 7 No. 9 p. 1079-1093 2010年9月
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悪性黒色腫の新規血清腫瘍マーカーとしての抗BPAG1抗体(Serum anti-BPAG1 auto-antibody is a novel marker for human melanoma)
新保 敬史, 種村 篤, 玉井 克人, 片山 一郎, 金田 安史
日本癌学会総会記事 Vol. 69回 p. 76-77 2010年8月
出版者・発行元:(一社)日本癌学会
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癌治療を目指した高性能HVJ-Eの全身投与による癌治療(Systemic injection of high performance HVJ-E for cancer therapy)
佐賀 公太郎, 玉井 克人, 金田 安史
日本癌学会総会記事 Vol. 69回 p. 101-101 2010年8月
出版者・発行元:(一社)日本癌学会
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HVJ-Eを利用した悪性黒色腫への新規免疫療法(A novel immunotherapy with HVJ envelope to malignant melanoma)
清原 英司, 種村 篤, 西岡 めぐみ, 山中 隆嗣, 谷 守, 李 千萬, 玉井 克人, 片山 一朗, 金田 安史, 河上 裕
日本癌学会総会記事 Vol. 69回 p. 101-101 2010年8月
出版者・発行元:日本癌学会
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[Current status of gene therapy in Japan and other countries].
Kaneda Y
Nihon rinsho. Japanese journal of clinical medicine Vol. 68 Suppl 8 p. 577-583 2010年8月
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Basic investigation of boron neutron capture therapy (BNCT) using HVJ-E and accelerator-based neutron source
M. Sakai, N. Fujimoto, K. Ishii, I. Murata, Y. Kaneda, K. Awazu
2010年6月 研究論文(その他学術会議資料等)
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Variation in OSBPL10 is associated with dyslipidemia
Hiroshi Koriyama, Hironori Nakagami, Tomohiro Katsuya, Hiroshi Akasaka, Shigeyuki Saitoh, Kazuaki Shimamoto, Toshio Ogihara, Yasufumi Kaneda, Ryuichi Morishita, Hiromi Rakugi
HYPERTENSION RESEARCH Vol. 33 No. 5 p. 511-514 2010年5月 研究論文(学術雑誌)
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Dodecaborate lipid liposomes as new vehicles for boron delivery system of neutron capture therapy
Manabu Ueno, Hyun Seung Ban, Kei Nakai, Ryu Inomata, Yasufumi Kaneda, Akira Matsumura, Hiroyuki Nakamura
BIOORGANIC & MEDICINAL CHEMISTRY Vol. 18 No. 9 p. 3059-3065 2010年5月 研究論文(学術雑誌)
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Serum Anti-BPAG1 Auto-Antibody Is a Novel Marker for Human Melanoma
Takashi Shimbo, Atsushi Tanemura, Takehiko Yamazaki, Katsuto Tamai, Ichiro Katayama, Yasufumi Kaneda
PLOS ONE Vol. 5 No. 5 2010年5月 研究論文(学術雑誌)
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Sterile alpha motif containing domain 9 is involved in death signaling of malignant glioma treated with inactivated Sendai virus particle (HVJ-E) or type I interferon
Masahiko Tanaka, Takashi Shimbo, Yasushi Kikuchi, Masahide Matsuda, Yasufumi Kaneda
INTERNATIONAL JOURNAL OF CANCER Vol. 126 No. 8 p. 1982-1991 2010年4月 研究論文(学術雑誌)
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Controlled Release of Bone Morphogenetic Protein-2 Enhances Recruitment of Osteogenic Progenitor Cells for De Novo Generation of Bone Tissue
Yu Kimura, Nobuhiko Miyazaki, Naoki Hayashi, Satoru Otsuru, Katsuto Tamai, Yasufumi Kaneda, Yasuhiko Tabata
TISSUE ENGINEERING PART A Vol. 16 No. 4 p. 1263-1270 2010年4月 研究論文(学術雑誌)
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メラノーマのすべて メラノーマ治療の展望
種村 篤, 清原 英司, 片山 一朗, 金田 安史, 河上 裕
日本皮膚科学会雑誌 Vol. 120 No. 3 p. 515-515 2010年3月
出版者・発行元:(公社)日本皮膚科学会
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非ウイルスベクターHVJ-Eを用いた光線力学療法の基礎検討
藤本 尚弘, 酒井 真理, 石井 克典, 金田 安史, M.E. El-Zaria, H.S. Ban, 中村 浩之, 粟津 邦男
2010年2月 研究論文(その他学術会議資料等)
-
Therapeutic strategies for controlling metastasis and recurrence of cancers
Yasufumi Kaneda
Drug Delivery System Vol. 25 No. 2 p. 94-102 2010年 研究論文(学術雑誌)
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非ウイルスベクターを用いたがんに対する光線力学療法
藤本尚弘, 酒井真理, 石井克典, M.E. El-Zaria, 潘鉉承, 中村浩之, 金田安史, 粟津邦男
2010年
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Identification of Evidence Suggestive of an Association with Peripheral Arterial Disease at the OSBPL10 Locus by Genome-Wide Investigation in the Japanese Population
Hiroshi Koriyama, Hironori Nakagami, Tomohiro Katsuya, Ken Sugimoto, Hidetoshi Yamashita, Yoichi Takami, Shiro Maeda, Michiaki Kubo, Atsushi Takahashi, Yusuke Nakamura, Toshio Ogihara, Hiromi Rakugi, Yasufumi Kaneda, Ryuichi Morishita
JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS Vol. 17 No. 10 p. 1054-1062 2010年 研究論文(学術雑誌)
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Highly efficient eradication of intracranial glioblastoma using Eg5 siRNA combined with HVJ envelope
Matsuda, M, Yamamoto, T, Matsumura, A, Kaneda, Y
GENE THERAPY Vol. 16 No. 12 p. 1465-1476 2009年12月 研究論文(学術雑誌)
出版者・発行元:NATURE PUBLISHING GROUP
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メラノーマ免疫療法 現況と展望 悪性黒色腫におけるHVJ-E腫瘍内投与による抗腫瘍効果の検討について
種村 篤, 清原 英司, 片山 一朗, 金田 安史, 河上 裕
Skin Cancer Vol. 24 No. 2 p. 181-191 2009年10月
出版者・発行元:(一社)日本皮膚悪性腫瘍学会
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加速器及びHVJ-E を用いたホウ素中性子捕捉療法の基礎的検討
藤本 尚弘, 酒井 真理, 石井 克典, 村田 勲, 粟津 邦男, 李 千萬, 金田 安史, 浅野 智之, 中村 浩之
2009年9月 研究論文(その他学術会議資料等)
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癌治療を目指した高性能免疫賦活化ビロソームの開発(Development of high-performance immunovirosome for cancer therapy)
佐賀 公太郎, 玉井 克人, 金田 安史
日本癌学会総会記事 Vol. 68回 p. 241-241 2009年8月
出版者・発行元:(一社)日本癌学会
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化学療法とRad51 siRNAを封入したHVJ-E併用の相乗効果によるメラノーマの抑制(The combination of chemotherapy with immune-competent HVJ-E containing Rad51 siRNA synergistically suppressed melanoma)
清原 英司, 玉井 克人, 片山 一朗, 金田 安史
日本癌学会総会記事 Vol. 68回 p. 88-88 2009年8月
出版者・発行元:日本癌学会
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Development of boron nanocapsules for neutron capture therapy
H. Nakamura, M. Ueno, H. S. Ban, K. Nakai, K. Tsuruta, Y. Kaneda, A. Matsumura
Applied Radiation and Isotopes Vol. 67 No. 7-8 p. S84-S87 2009年7月 研究論文(学術雑誌)
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大学院生を対象としたESPアプローチの医学英語論文講座の試みについて
馬場 幸子, 野口 ジュディー, 和佐 勝史, 渡部 健二, 倉智 嘉久, 金田 安史
医学教育 Vol. 40 No. Suppl. p. 57-57 2009年7月
出版者・発行元:(一社)日本医学教育学会
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Zyxin Mediates Actin Fiber Reorganization in Epithelial-Mesenchymal Transition and Contributes to Endocardial Morphogenesis
Masaki Mori, Hironori Nakagami, Nobutaka Koibuchi, Koichi Miura, Yoichi Takami, Hiroshi Koriyama, Hiroki Hayashi, Hisataka Sabe, Naoki Mochizuki, Ryuichi Morishita, Yasufumi Kaneda
MOLECULAR BIOLOGY OF THE CELL Vol. 20 No. 13 p. 3115-3124 2009年7月 研究論文(学術雑誌)
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A histone H3 lysine 36 trimethyltransferase links Nkx2-5 to Wolf-Hirschhorn syndrome
Keisuke Nimura, Kiyoe Ura, Hidetaka Shiratori, Masato Ikawa, Masaru Okabe, Robert J. Schwartz, Yasufumi Kaneda
NATURE Vol. 460 No. 7252 p. 287-U157 2009年7月 研究論文(学術雑誌)
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Molecular therapies for heritable blistering diseases
Katsuto Tamai, Yasufumi Kaneda, Jouni Uitto
TRENDS IN MOLECULAR MEDICINE Vol. 15 No. 7 p. 285-292 2009年7月
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Ex Vivo Transfer of Nuclear Factor-kappa B Decoy Ameliorates Hepatic Cold Ischemia/Reperfusion Injury
T. Yoshizumi, Y. Ikeda, Y. Kaneda, K. Sueishi
TRANSPLANTATION PROCEEDINGS Vol. 41 No. 5 p. 1504-1507 2009年6月 研究論文(学術雑誌)
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FHL-2 Suppresses VEGF-Induced Phosphatidylinositol 3-Kinase/Akt Activation via Interaction With Sphingosine Kinase-1
Hiroki Hayashi, Hironori Nakagami, Yoichi Takami, Hiroshi Koriyama, Masaki Mori, Katsuto Tamai, Jianxin Sun, Kaori Nagao, Ryuichi Morishita, Yasufumi Kaneda
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY Vol. 29 No. 6 p. 909-U331 2009年6月 研究論文(学術雑誌)
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[Progress of human gene therapy].
Kaneda Y
Nihon rinsho. Japanese journal of clinical medicine Vol. 67 No. 6 p. 1180-1184 2009年6月
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Eg5 siRNA Combined with HVJ Envelope Synergistically Induced Cell Death in Glioblastoma
Matsuda, Masahide, Yamamoto, Tetsuya, Matsumura, Akira, Kaneda, Yasufumi
MOLECULAR THERAPY Vol. 17 No. Suppl. 1 p. 0-0 2009年5月 研究論文(学術雑誌)
出版者・発行元:NATURE PUBLISHING GROUP
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Zyxin Mediates Actin Fiber Reorganization in Epithelial-Mesenchymal Transition and Contributes to Endocardial Morphogenesis
Mori Masaki, Nakagami Hironori, Koibuchi Nobutaka, Miura Koichi, Sabe Hisataka, Mochizuki Naoki, Kaneda Yasufumi
MOLECULAR THERAPY Vol. 17 2009年5月
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Efficient eradication of hormone-resistant human prostate cancers by inactivated Sendai virus particle
Yoshifumi Kawaguchi, Yasuhide Miyamoto, Takehiro Inoue, Yasufumi Kaneda
INTERNATIONAL JOURNAL OF CANCER Vol. 124 No. 10 p. 2478-2487 2009年5月 研究論文(学術雑誌)
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Novel prophylactic and therapeutic vaccine against tuberculosis
Masaji Okada, Yoko Kita, Toshihiro Nakajima, Noriko Kanamaru, Satomi Hashimoto, Tetsuji Nagasawa, Yasufumi Kaneda, Shigeto Yoshida, Yasuko Nishida, Hitoshi Nakatani, Kyoko Takao, Chie Kishigami, Yoshikazu Inoue, Makoto Matsumoto, David N. McMurray, E. C. dela Cruz, E. V. Tan, R. M. Abalos, J. A. Burgos, Paul Saunderson, Mitsunori Sakatani
VACCINE Vol. 27 No. 25-26 p. 3267-3270 2009年5月 研究論文(学術雑誌)
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遺伝性皮膚疾患の根治的治療法開発
玉井 克人, 山崎 尊彦, 知野 剛直, 金田 安史, 片山 一朗
角化症研究会記録集 Vol. 23 p. 142-147 2009年3月
出版者・発行元:角化症研究会事務局
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Development of a novel antimicrobial peptide, AG-30, with angiogenic properties
Tomoyuki Nishikawa, Hironori Nakagami, Akito Maeda, Ryuichi Morishita, Nobuhiko Miyazaki, Toshihiro Ogawa, Yasuhiko Tabata, Yasushi Kikuchi, Hiroki Hayashi, Yoshiro Tatsu, Noboru Yumoto, Katsuto Tamai, Kazunori Tomono, Yasufumi Kaneda
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE Vol. 13 No. 3 p. 535-546 2009年3月 研究論文(学術雑誌)
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Injection of HGF plasmid cDNA to prevent manifestation of Parkinson disease: a preclinical study using a primate model.
Koike H, Ishida A, Hayashi T, Shimamura M, Mizuno S, Nakamura T, Iida H, Ogihara T, Kaneda Y, Morishita R
Open Gene Therapy Journal Vol. 2 p. 38-44 2009年 研究論文(学術雑誌)
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Nonviral Retrograde Gene Transfer of Human Hepatocyte Growth Factor Improves Neuropathic Pain-related Phenomena in Rats
Toyokazu Tsuchihara, Sho Ogata, Koichi Nemoto, Takatoshi Okabayashi, Kuniaki Nakanishi, Naoki Kato, Ryuichi Morishita, Yasufumi Kaneda, Maki Uenoyama, Shinya Suzuki, Masatoshi Amako, Toshiaki Kawai, Hiroshi Arino
MOLECULAR THERAPY Vol. 17 No. 1 p. 42-50 2009年1月 研究論文(学術雑誌)
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ゲノムワイド関連解析による閉塞性動脈硬化症感受性遺伝子座の同定
郡山 弘, 中神 啓徳, 勝谷 友宏, 杉本 研, 山下 英俊, 鷹見 洋一, 赤坂 憲, 斎藤 重幸, 前田 士朗, 中村 裕輔, 金田 安史, 樂木 宏実, 森下 竜一, 島本 和明, 荻原 俊男
日本高血圧学会総会プログラム・抄録集 Vol. 31回 p. 170-170 2008年10月
出版者・発行元:(NPO)日本高血圧学会
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子宮局所における一過性遺伝子導入方法を用いた着床不全マウスモデルの作製
香山 晋輔, 中村 仁美, 谷口 武, 荻田 和秀, 熊澤 恵一, 張 慶, 筒井 建紀, 金田 安史, 木村 正
日本生殖医学会雑誌 Vol. 53 No. 4 p. 284-284 2008年10月
出版者・発行元:(一社)日本生殖医学会
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Cold shock domain protein A, novel endogenous regulator of angiogenesis in heart
Yukihiro Saito, Hironori Nakagami, Nobuyoshi Azuma, Ryuichi Morishita, Yasufumi Kaneda, Tadahiro Sasajima
Journal of Molecular and Cellular Cardiology Vol. 45 No. 4 2008年10月
出版者・発行元:Elsevier {BV}
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着床期子宮局所におけるSTAT-3活性の役割
中村 仁美, 香山 晋輔, 谷口 武, 荻田 和秀, 熊澤 恵一, 張 慶, 筒井 建紀, 古山 将康, 杉野 法広, 田村 博史, 金田 安史, 木村 正
日本内分泌学会雑誌 Vol. 84 No. 2 p. 629-630 2008年9月
出版者・発行元:(一社)日本内分泌学会
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損傷組織による骨髄由来間葉系前駆細胞動員機構(Recruiting mechanism of bone marrow mesenchymal progenitor cells by tissue injury)
玉井 克人, 金田 安史
日本癌学会総会記事 Vol. 67回 p. 300-300 2008年9月
出版者・発行元:(一社)日本癌学会
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Bone marrow cell transfer into fetal circulation can ameliorate genetic skin diseases by providing fibroblasts to the skin and inducing immune tolerance
Takenao Chino, Katsuto Tamai, Takehiko Yamazaki, Satoru Otsuru, Yasushi Kikuchi, Keisuke Nimura, Masayuki Endo, Miki Nagai, Jouni Uitto, Yasuo Kitajima, Yasufumi Kaneda
AMERICAN JOURNAL OF PATHOLOGY Vol. 173 No. 3 p. 803-814 2008年9月 研究論文(学術雑誌)
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Atrial natriuretic peptide gene transfection with a novel envelope vector system ameliorates pulmonary hypertension in rats
Yoshihide Mitani, Junko Maruyama, Bao Hua Jiang, Hirofumi Sawada, Hideto Shimpo, Kyoko Imanaka-Yoshida, Yasufumi Kaneda, Yoshihiro Komada, Kazuo Maruyama
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY Vol. 136 No. 1 p. 142-149 2008年7月 研究論文(学術雑誌)
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子宮局所における一過性遺伝子導入方法を用いたヒト不妊症のマウスモデルの作製
中村 仁美, 香山 晋輔, 荻田 和秀, 谷口 武, 筒井 建紀, 金田 安史, 木村 正
Drug Delivery System Vol. 23 No. 3 p. 417-417 2008年5月
出版者・発行元:日本DDS学会
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New potential therapy for orthotopic bladder carcinoma by combining HVJ envelope with doxorubicin
Hirokazu Kawano, Shintaro Komaba, Tsugiko Yamasaki, Mitsuyo Maeda, Yoshimitsu Kimura, Akito Maeda, Yasufumi Kaneda
CANCER CHEMOTHERAPY AND PHARMACOLOGY Vol. 61 No. 6 p. 973-978 2008年5月 研究論文(学術雑誌)
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Cutaneous gene delivery
Yasushi Kikuchi, Katsuto Tamai, Yasufumi Kaneda
JOURNAL OF DERMATOLOGICAL SCIENCE Vol. 50 No. 2 p. 87-98 2008年5月
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Identification of angiogenic and antimicrobial factor, AG-30, and analysis of its De Novo engineered variants
Tomoyuki Nishikawa, Hironori Nakagami, Akito Maeda, Nobuhiko Miyazaki, Yasuhiko Tabata, Ryuichi Morishita, Katsuto Tamai, Yasufumi Kaneda
JOURNAL OF GENE MEDICINE Vol. 10 No. 4 p. 473-473 2008年4月 研究論文(学術雑誌)
出版者・発行元:JOHN WILEY & SONS LTD
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Sendai virus F glycoprotein induces IL-6 production in dendritic cells in a fusion-independent manner
Hayato Suzuki, Masayuki Kurooka, Yoko Hiroaki, Yoshinori Fujiyoshi, Yasufumi Kaneda
FEBS LETTERS Vol. 582 No. 9 p. 1325-1329 2008年4月 研究論文(学術雑誌)
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創傷治療のニューウェーブ
玉井 克人, 金田 安史, 片山 一朗
日本皮膚科学会雑誌 Vol. 118 No. 4 p. 645-645 2008年3月
出版者・発行元:(公社)日本皮膚科学会
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Cold shock domain protein A represses angiogenesis and lymphangiogenesis via inhibition of serum response element.
Saito Y, Nakagami H, Kurooka M, Takami Y, Kikuchi Y, Hayashi H, Nishikawa T, Tamai K, Morishita R, Azuma N, Sasajima T, Kaneda Y, Oncogene
Vol. 27 No. 13 p. 1821-1833 2008年3月 研究論文(学術雑誌)
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Potential role of CYLD (cylindromatosis) as a deubiquitinating enzyme in vascular cells
Yoichi Takami, Hironori Nakagami, Ryuichi Morishita, Tomohiro Katsuya, Hiroki Hayashi, Masaki Mori, Hiroshi Koriyama, Yoshichika Baba, Osamu Yasuda, Hiromi Rakugi, Toshio Ogihara, Yasufumi Kaneda
AMERICAN JOURNAL OF PATHOLOGY Vol. 172 No. 3 p. 818-829 2008年3月 研究論文(学術雑誌)
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Current status of gene therapy in Asia
Sunyoung Kim, Zhaohui Peng, Yasufumi Kaneda
MOLECULAR THERAPY Vol. 16 No. 2 p. 237-243 2008年2月 研究論文(学術雑誌)
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Functional modification of Sendai virus by siRNA
Kotaro Saga, Katsuto Tamai, Masako Kawachi, Takashi Shimbo, Hiroshi Fujita, Takehiko Yamazaki, Yasufumi Kaneda
JOURNAL OF BIOTECHNOLOGY Vol. 133 No. 3 p. 386-394 2008年2月 研究論文(学術雑誌)
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Applications of Hemagglutinating Virus of Japan in therapeutic delivery systems
Yasufumi Kaneda
EXPERT OPINION ON DRUG DELIVERY Vol. 5 No. 2 p. 221-233 2008年2月
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OP-375 マウスRenca腎癌に対するSendai virus partide(HVJ-E)の抗腫瘍効果の検討(腎腫瘍/基礎,一般演題口演,第96回日本泌尿器科学会総会)
藤原 敦子, 三木 恒治, 金田 安史
日本泌尿器科学会雑誌 Vol. 99 No. 2 p. 365-365 2008年
出版者・発行元:一般社団法人 日本泌尿器科学会
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Polymorphism of myospryn is associated with left ventricular diastolic dysfunction
Kikuchi Yasushi, Nakagami Hironori, Katsuya Tomohiro, Morishita Ryuichi, Horio Takeshi, Kamide Kei, Miyata Toshiyuki, Kawano Yuhei, Takami Yoichi, Rakugi Hiromi, Kaneda Yasufumi, Ogihara Toshio
ANTI-AGING MEDICINE Vol. 5 No. 4 p. 49-52 2008年
出版者・発行元:Japanese Society of Anti-Aging Medicine
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Intratumoral injection of inactivated Sendai virus particles elicits strong antitumor activity by enhancing local CXCL10 expression and systemic NK cell activation
Atsuko Fujihara, Masayuki Kurooka, Tsuneharu Miki, Yasufumi Kaneda
CANCER IMMUNOLOGY IMMUNOTHERAPY Vol. 57 No. 1 p. 73-84 2008年1月 研究論文(学術雑誌)
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Circulating bone marrow-derived osteoblast progenitor cells are recruited to the bone-forming site by the CXCR4/stromal cell-derived factor-1 pathway
Satoru Otsuru, Katsuto Tamai, Takehiko Yamazaki, Hideki Yoshikawa, Yasufumi Kaneda
STEM CELLS Vol. 26 No. 1 p. 223-234 2008年 研究論文(学術雑誌)
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Development of a transferrin receptor-targeting HVXE vector
Takashi Shimbo, Masako Kawachi, Kotaro Saga, Hiroshi Fujita, Takehiko Yamazaki, Katsuto Tanial, Yasufunii Kaneda
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS Vol. 364 No. 3 p. 423-428 2007年12月 研究論文(学術雑誌)
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Gene polymorphism of myospryn (cardiomyopathy-associated 5) is associated with left ventricular wall thickness in patients with hypertension
Hironori Nakagami, Yasushi Kikuchi, Tomohiro Katsuya, Ryuichi Morishita, Hiroshi Akasaka, Shigeyuki Saitoh, Hiromi Rakugi, Yasufumi Kaneda, Kazuaki Shimamoto, Toshio Ogihara
HYPERTENSION RESEARCH Vol. 30 No. 12 p. 1239-1246 2007年12月 研究論文(学術雑誌)
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Regression of abdominal aortic aneurysms by simultaneous inhibition of nuclear factor kappa B and ets in a rabbit model
Takashi Miyake, Motokuni Aoki, Hisao Masaki, Tomio Kawasaki, Masako Oishi, Kazusaburo Kataoka, Toshio Ogihara, Yasufumi Kaneda, Ryuichi Morishita
CIRCULATION RESEARCH Vol. 101 No. 11 p. 1175-1184 2007年11月 研究論文(学術雑誌)
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Involvement of gamma-secretase in postnatal angiogenesis
Hiroki Hayashi, Hironori Nakagami, Yoichi Takami, Naoyuki Sato, Yukihiro Saito, Tomoyuki Nishikawa, Masaki Mori, Hiroshi Koriyama, Katsuto Tamai, Ryuichi Morishita, Yasufumi Kaneda
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS Vol. 363 No. 3 p. 584-590 2007年11月 研究論文(学術雑誌)
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脱ユビキチン化酵素CYLD(cylindromatosis)の血管における機能
鷹見 洋一, 中神 啓徳, 森下 竜一, 勝谷 友宏, 楽木 宏実, 金田 安史, 荻原 俊男
日本高血圧学会総会プログラム・抄録集 Vol. 30回 p. 160-160 2007年10月
出版者・発行元:(NPO)日本高血圧学会
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Ubiquitin carboxyl-terminal hydrolase L1, a novel deubiquitinating enzyme in the vasculature, attenuates NF-kappa B activation
Yoichi Takami, Hironori Nakagami, Ryuichi Morishita, Tomohiro Katsuya, Tai-Xing Cui, Tomonaga Ichikawa, Yukihiro Saito, Hiroki Hayashi, Yasushi Kikuchi, Tomoyuki Nishikawa, Yoshichika Baba, Osamu Yasuda, Hiromi Rakugi, Toshio Ogihara, Yasufumi Kaneda
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY Vol. 27 No. 10 p. 2184-2190 2007年10月 研究論文(学術雑誌)
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Development of tissue-targeting hemagglutinating virus of Japan envelope vector for successful delivery of therapeutic gene to mouse skin
Masako Kawachi, Katsuto Tamai', Kotaro Saga, Takehiko Yamazaki, Hiroshi Fujita, Takashi Shimbo, Yasushi Kikuchi, Keisuke Nimura, Koji Nishifuji, Masayuki Amagai, Jouni Uitto, Yasufumi Kaneda
HUMAN GENE THERAPY Vol. 18 No. 10 p. 881-894 2007年10月 研究論文(学術雑誌)
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Selective inactivation of NF-kappa B in the liver using NF-kappa B decoy suppresses CCl4-induced liver injury and fibrosis
Gakuhei Son, Yuji Iimuro, Ekihiro Seki, Tadamichi Hirano, Yasufumi Kaneda, Jiro Fujimoto
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY Vol. 293 No. 3 p. G631-G639 2007年9月 研究論文(学術雑誌)
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A new therapy for highly effective tumor eradication using HVJ-E combined with chemotherapy
Hirokazu Kawano, Shintarou Komaba, Toshihide Kanamori, Yasufumi Kaneda
BMC MEDICINE Vol. 5 2007年9月 研究論文(学術雑誌)
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運動器の再生 骨折治癒 生体内骨形成プロセスにおける骨髄由来骨前駆細胞関与のメカニズム
大鶴 聰, 玉井 克人, 山崎 尊彦, 吉川 秀樹, 金田 安史
日本整形外科学会雑誌 Vol. 81 No. 8 p. S890-S890 2007年8月
出版者・発行元:(公社)日本整形外科学会
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Effect on vein graft intimal hyperplasia of nuclear factor-kappa B decoy transfection using the second generation of HVJ vector
N. Shimizu, N. Azuma, T. Nishikawa, S. Hirata, R. Morishita, Y. Kaneda, T. Sasajima
JOURNAL OF CARDIOVASCULAR SURGERY Vol. 48 No. 4 p. 463-470 2007年8月 研究論文(学術雑誌)
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Epstein-Barr virus-based vector improves the tumor cell killing effect of pituitary tumor in HVJ-liposome-mediated transcriptional targeting suicide gene therapy
Tsuyoshi Izumo, Akira Ohtsuru, Yoshiharu Tokunaga, Hiroyuki Namba, Yasufumi Kaneda, Izumi Nagata, Shunichi Yamashita
INTERNATIONAL JOURNAL OF ONCOLOGY Vol. 31 No. 2 p. 379-387 2007年8月 研究論文(学術雑誌)
-
[Development of viral envelope-based drug delivery vectors].
Kaneda Y
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme Vol. 52 No. 10 Suppl p. 1268-1273 2007年8月
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Differential regulation of karyopherin alpha 2 expression by TGF-beta(1), and IFN-gamma in normal human epidermal keratinocytes: Evident contribution of KPNA2 for nuclear translocation of IRF-1
Noriko Umegaki, Katsuto Tamai, Hajime Nakano, Ryuta Moritsugu, Takehiko Yamazaki, Katsumi Hanada, Ichiro Katayama, Yasufumi Kaneda
JOURNAL OF INVESTIGATIVE DERMATOLOGY Vol. 127 No. 6 p. 1456-1464 2007年6月 研究論文(学術雑誌)
-
[Anticancer immunotherapy using inactivated Sendai virus particles].
Kurooka M, Kaneda Y
Uirusu Vol. 57 No. 1 p. 19-27 2007年6月
出版者・発行元:日本ウイルス学会
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Evaluation of a novel vaccine (HVJ-liposome/HSP65 DNA+IL-12 DNA) against tuberculosis using the cynomolgus monkey model of TB
Masaji Okada, Yoko Kita, Toshihiro Nakajima, Noriko Kanamaru, Satomi Hashimoto, Tetsuji Nagasawa, Yasufumi Kaneda, Shigeto Yoshida, Yasuko Nishida, Reiko Fukamizu, Yoshie Tsunai, Ruriko Inoue, Hitoshi Nakatani, Yumi Namie, Junko Yamada, Kyoko Takao, Ritsuko Asai, Ryoko Asaki, Makoto Matsumoto, David N. McMurray, E. C. Dela Cruz, E. V. Tan, R. M. Abalos, J. A. Burgos, Robert Gelber, Mitsunori Sakatani
VACCINE Vol. 25 No. 16 p. 2990-2993 2007年4月 研究論文(学術雑誌)
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Comparative roles of Twist-1 and Id1 in transcriptional regulation by BMP signaling
Masanori Hayashi, Keisuke Nimura, Katsunobu Kashiwagi, Taku Harada, Kunio Takaoka, Hiroyuki Kato, Katsuto Tamai, Yasufumi Kaneda
JOURNAL OF CELL SCIENCE Vol. 120 No. 8 p. 1350-1357 2007年4月 研究論文(学術雑誌)
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骨髄細胞による表皮形成
玉井 克人, 山崎 尊彦, 菊池 康, 知野 剛直, 金田 安史
角化症研究会記録集 Vol. 21 p. 34-37 2007年3月
出版者・発行元:角化症研究会事務局
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Needleless intranasal administration of HVJ-E containing allergen attenuates experimental allergic rhinitis
Eri Yasuoka, Kazuo Oshima, Katsuto Tamai, Takeshi Kubo, Yasufumi Kaneda
JOURNAL OF MOLECULAR MEDICINE-JMM Vol. 85 No. 3 p. 279-288 2007年3月 研究論文(学術雑誌)
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Bone marrow-derived osteoblast progenitor cells in circulating blood contribute to ectopic bone formation in mice
Satoru Otsuru, Katsuto Tamai, Takehiko Yamazaki, Hideki Yoshikawa, Yasufumi Kaneda
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS Vol. 354 No. 2 p. 453-458 2007年3月 研究論文(学術雑誌)
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APP-007 不活化 Sendai virus particle (HVJ-E) によるマウス腎癌細胞に対する抗腫瘍効果の機序の検討(第95回日本泌尿器科学会総会)
藤原 敦子, 三木 恒治, 金田 安史
日本泌尿器科学会雑誌 Vol. 98 No. 2 p. 244-244 2007年
出版者・発行元:一般社団法人 日本泌尿器科学会
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Novel vaccination (HVJ-liposome/HSP65 DNA+ IL-12 DNA) against tuberculosis using cynomolgus monkey
M. Okada, Y. Kita, T. Nakajima, N. Kanamaru, S. Hashimoto, T. Nagasawa, Y. Kaneda, Y. Nishida, H. Nakatani, K. Takao, R. Asai, R. Suhara, E. C. Dela Cruz, E. V. Tan, R. M. Abajos, R. Gelber, P. Sanderson, S. Yoshida, M. Matsumoto, D. McMurray, M. Sakatani
13TH INTERNATIONAL CONGRESS OF IMMUNOLOGY p. 119-+ 2007年 研究論文(国際会議プロシーディングス)
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Immunity against breast cancer by TERT DNA vaccine primed with chemokine CCL21
山野智基
Cancer gene therapy Vol. 14 No. 5 p. 451-459 2007年 研究論文(学術雑誌)
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Rapid transport of plasmid DNA into the nucleolus via actin depolymerization using the HVJ envelope vector
Saroj Suvanasuthi, Katsuto Tamai, Yasufumi Kaneda
JOURNAL OF GENE MEDICINE Vol. 9 No. 1 p. 55-62 2007年1月 研究論文(学術雑誌)
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Inactivated Sendai virus particles eradicate tumors by inducing immune responses through blocking regulatory T cells
Masayuki Kurooka, Yasufumi Kaneda
CANCER RESEARCH Vol. 67 No. 1 p. 227-236 2007年1月 研究論文(学術雑誌)
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Delivery of viral vectors to hepatic stellate cells in fibrotic livers using HVJ envelopes fused with targeted liposomes
Joanna E. Adrian, Jan A. A. M. Kamps, Klaas Poelstra, Gerrit L. Scherphof, Dirk K. F. Meijer, Yasufumi Kaneda
JOURNAL OF DRUG TARGETING Vol. 15 No. 1 p. 75-82 2007年 研究論文(学術雑誌)
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Transient local overexpression of human vascular endothelial growth factor (VEGF) in mouse feto-maternal interface during mid-term pregnancy lowers systemic maternal blood pressure.
Koyama S, Kimura T, Ogita K, Nakamura H, Khan MA, Yoshida S, Watanabe M, Shimoya K, Kaneda Y, Murata Y
Horm Metab Res. Vol. 38 No. 10 p. 619-624 2006年10月 研究論文(学術雑誌)
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Hypertension accelerated experimental abdominal aortic aneurysm through upregulation of nuclear factor kappa B and ets
Suguru Shiraya, Ken Miwa, Motokuni Aoki, Takashi Miyake, Masako Oishi, Kazusaburo Kataoka, Shigetsup Ohgi, Toshio Ogihara, Yasufutni Kaneda, Ryuichi Morishita
HYPERTENSION Vol. 48 No. 4 p. 628-636 2006年10月 研究論文(学術雑誌)
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Dnmt3a2 targets endogenous Dnmt3L to ES cell chromatin and induces regional DNA methylation
Keisuke Nimura, Chisaki Ishida, Hiroshi Koriyama, Kenichiro Hata, Shinya Yamanaka, En Li, Kiyoe Ura, Yasufumi Kaneda
GENES TO CELLS Vol. 11 No. 10 p. 1225-1237 2006年10月 研究論文(学術雑誌)
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NFκBデコイDNA軟膏によるアトピー性皮膚炎治療
玉井 克人, 金田 安史, 森下 竜一, 片山 一朗
感染・炎症・免疫 Vol. 36 No. 3 p. 238-240 2006年9月
出版者・発行元:鳥居薬品(株)
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Inhibitory effects of NF kappa B decoy oligodeoxynucleotides on neointimal hyperplasia in a rabbit vein graft model
Takashi Miyake, Motokuni Aoki, Suguru Shiraya, Kazuo Tanemoto, Toshio Ogihara, Yasufumi Kaneda, Ryuichi Morishita
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY Vol. 41 No. 3 p. 431-440 2006年9月 研究論文(学術雑誌)
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Transfection of human hepatocyte growth factor gene ameliorates secondary lymphedema via promotion of lymphangiogenesis
Yukihiro Saito, Hironori Nakagami, Ryuichi Morishita, Yoichi Takami, Yasushi Kikuchi, Hiroki Hayashi, Tomoyuki Nishikawa, Katsuto Tamai, Nobuyoshi Azuma, Tadahiro Sasajima, Yasufumi Kaneda
CIRCULATION Vol. 114 No. 11 p. 1177-1184 2006年9月 研究論文(学術雑誌)
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Novel drug delivery system by surface modified magnetic nanoparticles
Shin-ichi Takeda, Bungo Terazono, Fumihito Mishima, Hironori Nakagami, Shigehiro Nishijima, Yasufumi Kaneda
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY Vol. 6 No. 9-10 p. 3269-3276 2006年9月 研究論文(学術雑誌)
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E2F decoy oligodeoxynucleotide ameliorates cartilage invasion by infiltrating synovium derived from rheumatoid arthritis
Tetsuya Tomita, Yasuo Kunugiza, Naruya Tomita, Hiroshi Takano, Ryuichi Morishita, Yasufumi Kaneda, Hideki Yoshikawa
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE Vol. 18 No. 2 p. 257-265 2006年8月 研究論文(学術雑誌)
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NFkappaB decoy oligodeoxynucleotides ameliorates osteoporosis through inhibition of activation and differentiation of osteoclasts.
Shimizu H, Nakagami H, Tsukamoto I, Morita S, Kunugiza Y, Tomita T, Yoshikawa H, Kaneda Y, Ogihara T, Morishita R, Gene therapy
Vol. 13 No. 12 p. 933-941 2006年6月
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Simple and highly efficient method for transient in vivo gene transfer to mid-late pregnant mouse uterus
S Koyama, T Kimura, K Ogita, H Nakamura, C Tabata, KMAHN Ali, K Temma-Asano, K Shimoya, T Tsutsui, M Koyama, Y Kaneda, Y Murata
JOURNAL OF REPRODUCTIVE IMMUNOLOGY Vol. 70 No. 1-2 p. 59-69 2006年6月 研究論文(学術雑誌)
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Total vascular exclusion safely facilitates liver specific gene transfer by the HVJ (sendai virus)-liposome method in rats
Y Kawashita, H Fujioka, A Ohtsuru, H Kuroda, S Eguchi, Y Kaneda, S Yamashita, T Kanematsu
JOURNAL OF SURGICAL RESEARCH Vol. 132 No. 1 p. 136-141 2006年5月 研究論文(学術雑誌)
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Tumor necrosis factor-alpha antisense transfer remarkably improves hepatic graft viability
T Yoshizumi, Y Yonemitsu, Y Ikeda, Y Kaneda, K Yanaga, K Sugimachi, K Sueishi
LIVER INTERNATIONAL Vol. 26 No. 4 p. 451-456 2006年5月 研究論文(学術雑誌)
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Non-viral vectors for cancer therapy
Y Kaneda, Y Tabata
CANCER SCIENCE Vol. 97 No. 5 p. 348-354 2006年5月
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The effect of VEGF on blood vessels and blood cells during Xenopus development
N Koibuchi, Y Taniyama, K Nagao, T Ogihara, Y Kaneda, R Morishita
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS Vol. 344 No. 1 p. 339-345 2006年5月 研究論文(学術雑誌)
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Mouse model of human infertility: Transient and local inhibition of endometrial STAT-3 activation results in implantation failure
H Nakamura, T Kimura, S Koyama, K Ogita, T Tsutsui, K Shimoya, T Taniguchi, M Koyama, Y Kaneda, Y Murata
FEBS LETTERS Vol. 580 No. 11 p. 2717-2722 2006年5月 研究論文(学術雑誌)
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Interferon-gamma down-regulates expression of the 230-kDa bullous pemphigoid antigen gene (BPAG1) in epidermal keratinocytes via novel chimeric sequences of ISRE and GAS.
Kaneko T, Tamai K, Matsuzaki Y, Yamazaki T, Nakano H, Kon A, Hashimoto I, Hanada K, Kaneda Y, Uitto J
Experimental dermatology Vol. 15 No. 4 p. 308-314 2006年4月
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Gene transfer of hepatocyte growth factor gene improves learning and memory in the chronic stage of cerebral infarction
M Shimamura, N Sato, S Waguri, Y Uchiyama, T Hayashi, H Iida, T Nakamura, T Ogihara, Y Kaneda, R Morishita
HYPERTENSION Vol. 47 No. 4 p. 742-751 2006年4月 研究論文(学術雑誌)
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Development of high-throughput functional screening of therapeutic genes, using a hemagglutinating virus of Japan envelope vector
T Nishikawa, H Nakagami, A Matsuki, A Maeda, CY Yo, T Harada, R Morishita, K Tamai, Y Kaneda
HUMAN GENE THERAPY Vol. 17 No. 4 p. 470-475 2006年4月 研究論文(学術雑誌)
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Construction of a novel DNA decoy that inhibits the oncogenic beta-catenin/T-cell factor pathway
Y Seki, H Yamamoto, CY Ngan, M Yasui, N Tomita, K Kitani, Takemasa, I, M Ikeda, M Sekimoto, N Matsuura, C Albanese, Y Kaneda, RG Pestell, M Monden
MOLECULAR CANCER THERAPEUTICS Vol. 5 No. 4 p. 985-994 2006年4月 研究論文(学術雑誌)
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Targeted chemotherapy against intraperitoneally disseminated colon carcinoma using a cationized gelatin-conjugated HVJ envelope vector
H Mima, S Yamamoto, M Ito, R Tomoshige, Y Tabata, K Tamai, Y Kaneda
MOLECULAR CANCER THERAPEUTICS Vol. 5 No. 4 p. 1021-1028 2006年4月 研究論文(学術雑誌)
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Anti-oxidant gene therapy by NF kappa B decoy oligodeoxynucleotide
Hironori Nakagami, Naruya Tomita, Yasufumi Kaneda, Toshio Ogihara, Ryuichi Morishita
CURRENT PHARMACEUTICAL BIOTECHNOLOGY Vol. 7 No. 2 p. 95-100 2006年4月
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Adipose tissue-derived stromal cells as a novel option for regenerative cell therapy
H Nakagami, R Morishita, K Maeda, Y Kikuchi, T Ogihara, Y Kaneda
JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS Vol. 13 No. 2 p. 77-81 2006年4月
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In vitro RNA interference against beta-catenin inhibits the proliferation of pediatric hepatic tumors
S Sangkhathat, T Kusafuka, JY Miao, A Yoneda, K Nara, S Yamamoto, Y Kaneda, M Fukuzawa
INTERNATIONAL JOURNAL OF ONCOLOGY Vol. 28 No. 3 p. 715-722 2006年3月 研究論文(学術雑誌)
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Heat-directed suicide gene therapy mediated by heat shock protein promoter for gastric cancer
H Isomoto, A Ohtsuru, Braiden, V, M Iwamatsu, F Miki, Y Kawashita, Y Mizuta, Y Kaneda, S Kohno, S Yamashita
ONCOLOGY REPORTS Vol. 15 No. 3 p. 629-635 2006年3月 研究論文(学術雑誌)
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Liver-directed gene therapy of diabetic rats using an HVJ-E vector containing EBV plasmids expressing insulin and GLUT 2 transporter
YD Kim, KG Park, R Morishita, Y Kaneda, SY Kim, DK Song, HS Kim, CW Nam, HC Lee, KU Lee, JY Park, BW Kim, JG Kim, IK Lee
GENE THERAPY Vol. 13 No. 3 p. 216-224 2006年2月 研究論文(学術雑誌)
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DNA vaccine using hemagglutinating virus of Japan-liposome encapsulating combination encoding mycobacterial heat shock protein 65 and interleukin-12 confers protection against Mycobacterium tuberculosis by T cell activation
S Yoshida, T Tanaka, Y Kita, S Kuwayama, N Kanamaru, Y Muraki, S Hashimoto, Y Inoue, M Sakatani, E Kobayashi, Y Kaneda, M Okada
VACCINE Vol. 24 No. 8 p. 1191-1204 2006年2月 研究論文(学術雑誌)
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Prevention of onset of Parkinson's disease by in vivo gene transfer of human hepatocyte growth factor in rodent model: a model of gene therapy for Parkinson's disease.
Koike H, Ishida A, Shimamura M, Mizuno S, Nakamura T, Ogihara T, Kaneda Y, Morishita R
Gene Therapy Vol. 13 p. 1639-1644 2006年
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Enhancement of immunity by a DNA melanoma vaccine against TRP2 with CCL21 as an adjuvant
T Yamano, Y Kaneda, S Huang, SH Hiramatsu, DSB Hoon
MOLECULAR THERAPY Vol. 13 No. 1 p. 194-202 2006年1月 研究論文(学術雑誌)
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HVJ-based non-viral gene transfer method: successful gene therapy using HGF and VEGF genes in experimental ischemia
M Shimamura, N Sato, S Yoshimura, Y Kaneda, R Morishita
FRONTIERS IN BIOSCIENCE Vol. 11 p. 753-759 2006年1月 研究論文(学術雑誌)
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Novel autologous cell therapy in ischemic limb disease through growth factor secretion by cultured adipose tissue-derived stromal cells
H Nakagami, K Maeda, R Morishita, S Iguchi, T Nishikawa, Y Takami, Y Kikuchi, Y Saito, K Tamai, T Ogihara, Y Kaneda
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY Vol. 25 No. 12 p. 2542-2547 2005年12月 研究論文(学術雑誌)
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Assembly of additional heterochromatin distinct from centromere-kinetochore chromatin is required for de novo formation of human artificial chromosome
H Nakashima, M Nakano, R Ohnishi, Y Hiraoka, Y Kaneda, A Sugino, H Masumoto
JOURNAL OF CELL SCIENCE Vol. 118 No. 24 p. 5885-5898 2005年12月 研究論文(学術雑誌)
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The efficacy and safety of gene transfer into the porcine liver in vivo by HVJ (Sendai virus) liposome
Y Kawashita, H Fujioka, A Ohtsuru, Y Kaneda, Y Kamohara, Y Kawazoe, S Yamashita, T Kanematsu
TRANSPLANTATION Vol. 80 No. 11 p. 1623-1629 2005年12月 研究論文(学術雑誌)
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[Current status and future prospective of gene therapy].
Kaneda Y
Nihon rinsho. Japanese journal of clinical medicine Vol. 63 Suppl 12 p. 469-474 2005年12月
-
[Strategies for gene therapy].
Kaneda Y
Nihon rinsho. Japanese journal of clinical medicine Vol. 63 Suppl 12 p. 486-490 2005年12月
-
[Future view of gene therapy in cardiovascular field].
Nkagami H, Kaneda Y, Morishita R
Nihon rinsho. Japanese journal of clinical medicine Vol. 63 Suppl 12 p. 577-581 2005年12月
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NFkappaB decoy DNA for treatment of atopic dermatitis
Katsuto Tamai, Yasufumi Kaneda, Hiroshige Nakamura, Motohiro Aoki, Ryuichi Morishita, Koji Hashimoto, Akimichi Morita, Ichiro Katayama, Katsumi Hanada
Nippon rinsho. Japanese journal of clinical medicine Vol. 63 Suppl 12 p. 659-663 2005年12月
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Gene transfer into adult rat spinal cord using naked plasmid DNA and ultrasound microbubbles
M Shimamura, N Sato, Y Taniyama, H Kurinami, H Tanaka, T Takami, T Ogihara, M Tohyama, Y Kaneda, R Morishita
JOURNAL OF GENE MEDICINE Vol. 7 No. 11 p. 1468-1474 2005年11月 研究論文(学術雑誌)
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Microbubble-enhanced ultrasound for gene transfer into living skin equivalents
LJ Yang, Y Shirakata, K Tamai, XJ Dai, Y Hanakawa, S Tokumaru, Y Yahata, M Tohyama, K Shiraishi, H Nagai, XL Wang, S Murakami, K Sayama, Y Kaneda, K Hashimoto
JOURNAL OF DERMATOLOGICAL SCIENCE Vol. 40 No. 2 p. 105-114 2005年11月 研究論文(学術雑誌)
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Gene transfer of prostaglandin synthase maintains patency of the newborn lamb arterial duct
T Humpl, SHE Zaidi, JY Coe, J Russell, Y Kaneda, H Massaeli, LN Benson, M Rabinovitch
PEDIATRIC RESEARCH Vol. 58 No. 5 p. 976-980 2005年11月 研究論文(学術雑誌)
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In vivo gene transfer into the mouse uterus: A powerful tool for investigating implantation physiology
T Kimura, H Nakamura, S Koyama, K Ogita, C Tabata, T Tsutsui, K Shimoya, M Koyama, Y Kaneda, Y Murata
JOURNAL OF REPRODUCTIVE IMMUNOLOGY Vol. 67 No. 1-2 p. 13-20 2005年10月 研究論文(学術雑誌)
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HVJ-Eベクターを用いたHigh Throughput Screeningによる新規遺伝子機能スクリーニング 血管リモデリング抑制遺伝子の検索
鷹見 洋一, 中神 啓徳, 勝谷 友宏, 楽木 宏実, 森下 竜一, 金田 安史, 荻原 俊男
日本高血圧学会総会プログラム・抄録集 Vol. 28回 p. 84-84 2005年9月
出版者・発行元:(NPO)日本高血圧学会
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Hepatocyte growth factor(HGF)によるリンパ管新生作用
斉藤 幸裕, 中神 啓徳, 鷹見 洋一, 森下 竜一, 金田 安史, 東 信良, 笹嶋 唯博
日本高血圧学会総会プログラム・抄録集 Vol. 28回 p. 87-87 2005年9月
出版者・発行元:(NPO)日本高血圧学会
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Development of novel method of non-viral efficient gene transfer into neonatal cardiac myocytes
H Tashiro, M Aoki, M Isobe, N Hashiya, H Makino, Y Kaneda, T Ogihara, R Morishita
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY Vol. 39 No. 3 p. 503-509 2005年9月 研究論文(学術雑誌)
-
Magnetic nanoparticles with surface modification enhanced gene delivery of HVJ-E vector
N Morishita, H Nakagami, R Morishita, S Takeda, F Mishima, B Terazono, S Nishijima, Y Kaneda, N Tanaka
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS Vol. 334 No. 4 p. 1121-1126 2005年9月 研究論文(学術雑誌)
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Gene transfection with human hepatocyte growth factor complementary DNA plasmids attenuates cardiac remodeling after acute myocardial infarction in goat hearts implanted with ventricular assist devices
Y Shirakawa, Y Sawa, Y Takewa, E Tatsumi, Y Kaneda, Y Taenaka, H Matsuda
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY Vol. 130 No. 3 p. 624-632 2005年9月 研究論文(学術雑誌)
-
Rad51 siRNA delivered by HVJ envelope vector enhances the anti-cancer effect of cisplatin
M Ito, S Yamamoto, K Nimura, K Hiraoka, K Tamai, Y Kaneda
JOURNAL OF GENE MEDICINE Vol. 7 No. 8 p. 1044-1052 2005年8月 研究論文(学術雑誌)
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Nonviral HVJ (hemagglutinating virus of Japan) liposome-mediated retrograde gene transfer of human hepatocyte growth factor into rat nervous system promotes functional and histological recovery of the crushed nerve
N Kato, K Nemoto, K Nakanishi, R Morishita, Y Kaneda, M Uenoyama, T Ikeda, K Fujikawa
NEUROSCIENCE RESEARCH Vol. 52 No. 4 p. 299-310 2005年8月 研究論文(学術雑誌)
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Inhibition of ets, an essential transcription factor for angiogenesis, to prevent the development of abdominal aortic aneurysm in a rat model.
Miwa K, Nakashima H, Aoki M, Miyake T, Kawasaki T, Iwai M, Oishi M, Kataoka, K, Ohgi S, Ogihara T, Kaneda Y, Morishita R
Gene Therapy 2005年7月 研究論文(学術雑誌)
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Biocompatible polymer enhances the in vitro and in vivo transfection efficiency of HVJ envelope vector
H Mima, R Tomoshige, T Kanamori, Y Tabata, S Yamamoto, S Ito, K Tamai, Y Kaneda
JOURNAL OF GENE MEDICINE Vol. 7 No. 7 p. 888-897 2005年7月 研究論文(学術雑誌)
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Induction of compensatory lung growth in pulmonary emphysema improves surgical outcomes in rats
N Shigemura, Y Sawa, S Mizuno, M Ono, M Minami, M Okumura, T Nakamura, Y Kaneda, H Matsuda
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Vol. 171 No. 11 p. 1237-1245 2005年6月 研究論文(学術雑誌)
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Hepatocyte growth factor gene therapy reduces ventricular arrhythmia in animal models of myocardial ischemia
A Yumoto, KF Kusano, K Nakamura, K Hashimoto, M Aoki, R Morishita, Y Kaneda, T Ohe
ACTA MEDICA OKAYAMA Vol. 59 No. 3 p. 73-78 2005年6月 研究論文(学術雑誌)
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Hepatocyte growth factor as potential cardiovascular therapy
Hironori Nakagami, Yasufumi Kaneda, Toshio Ogihara, Ryuichi Morishita
Expert Review of Cardiovascular Therapy Vol. 3 No. 3 p. 513-519 2005年5月
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Hemagglutinating virus of Japan-artificial viral envelope liposome-mediated cotransfer of bag-1 and bcl-2 genes protects hepatic cells against ischemic injury through BAG-1-Assisted preferential enhancement of Bcl-2 protein expression
S Yanada, M Sasaki, S Takayama, Y Kaneda, N Miwa
HUMAN GENE THERAPY Vol. 16 No. 5 p. 627-633 2005年5月 研究論文(学術雑誌)
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超音波とマイクロバブルを用いた三次元皮膚への遺伝子導入
楊 旅軍, 白方 裕司, 花川 靖, 玉井 克人, 金田 安史, 橋本 公二
日本研究皮膚科学会年次学術大会・総会プログラム Vol. 30回 p. 92-92 2005年4月
出版者・発行元:(一社)日本研究皮膚科学会
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Ameliorating effect of hepatocyte growth factor on inflammatory bowel disease in a murine model
K Oh, Y Iimuro, M Takeuchi, Y Kaneda, T Iwasaki, N Terada, T Matsumoto, K Nakanishi, J Fujimoto
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY Vol. 288 No. 4 p. G729-G735 2005年4月 研究論文(学術雑誌)
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Linker histone variants control chromatin dynamics during early embryogenesis
H Saeki, K Ohsumi, H Aihara, T Ito, S Hirose, K Ura, Y Kaneda
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA Vol. 102 No. 16 p. 5697-5702 2005年4月 研究論文(学術雑誌)
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The effect of gene transfer with hepatocyte growth factor for pulmonary vascular hypoplasia in neonatal porcine model
M Ono, Y Sawa, Y Miyamoto, N Fukushima, H Ichikawa, T Ishizaka, Y Kaneda, H Matsuda
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY Vol. 129 No. 4 p. 740-745 2005年4月 研究論文(学術雑誌)
-
遺伝性皮膚疾患の遺伝子治療法開発
玉井 克人, 山崎 尊彦, 大鶴 聡, 知野 剛直, 菊池 康, 金田 安史, 片山 一朗
角化症研究会記録集 Vol. 19 p. 52-55 2005年3月
出版者・発行元:角化症研究会事務局
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Nonviral gene transfer of human hepatocyte growth factor improves streptozotocin-induced diabetic neuropathy in rats
N Kato, K Nemoto, K Nakanishi, R Morishita, Y Kaneda, M Uenoyama, T Ikeda, K Fujikawa
DIABETES Vol. 54 No. 3 p. 846-854 2005年3月 研究論文(学術雑誌)
-
Novel recombinant BCG and DNA-vaccination against tuberculosis in a cynomolgus monkey
Y Kita, T Tanaka, S Yoshida, N Ohara, Y Kaneda, S Kuwayama, Y Muraki, N Kanamaru, S Hashimoto, H Takai, C Okada, Y Fukunaga, Y Sakaguchi, IN Furukawa, K Yamada, Y Inoue, Y Takemoto, M Naito, T Yamada, M Matsumoto, DN McMurray, EC Dela Cruz, EV Tan, RM Abalos, JA Burgos, R Gelber, Y Skeiky, S Reed, M Sakatani, M Okada
VACCINE Vol. 23 No. 17-18 p. 2132-2135 2005年3月 研究論文(学術雑誌)
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Amelioration of pulmonary emphysema by in vivo gene transfection with hepatocyte growth factor in rats
N Shigemura, Y Sawa, S Mizuno, M Ono, M Ohta, T Nakamura, Y Kaneda, H Matsuda
CIRCULATION Vol. 111 No. 11 p. 1407-1414 2005年3月 研究論文(学術雑誌)
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妊娠中期後期の妊娠関連事象研究のための一過性遺伝子導入系の開発
香山 晋輔, 木村 正, 中村 仁美, 荻田 和秀, 田畑 知沙, 古山 将康, 村田 雄二, 金田 安史
日本産科婦人科学会雑誌 Vol. 57 No. 2 p. 546-546 2005年2月
出版者・発行元:(公社)日本産科婦人科学会
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Endothelial dysfunction in hyperglycemia as a trigger of atherosclerosis.
Nakagami H, Kaneda Y, Ogihara T, Morishita R
Current diabetes reviews Vol. 1 No. 1 p. 59-63 2005年2月
-
Endothelial Dysfunction in Hyperglycemia as a Trigger of Atherosclerosis.
Nakagami H, Kaneda Y, Ogihara T, Morishita R
Current Diabetes Reviews 2005年1月
-
Endothelial dysfunction in hyperglycemia as a trigger of atherosclerosis.
中神啓徳, 金田安史, 荻原俊男, 森下竜一
Current Diabetes Reviews 2005年1月 研究論文(学術雑誌)
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Development of HVJ Envelope Vector and Its Application to Gene Therapy
Yasufumi Kaneda, Seiji Yamamoto, Toshihiro Nakajima
NON-VIRAL VECTORS FOR GENE THERAPY, 2ND EDITION: PART 1 Vol. 53 p. 307-332 2005年 論文集(書籍)内論文
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Development of HVJ Envelope Vector and Its Application to Gene Therapy
Yasufumi Kaneda, Seiji Yamamoto, Toshihiro Nakajima
NON-VIRAL VECTORS FOR GENE THERAPY, 2ND EDITION: PART 1 Vol. 53 p. 307-332 2005年 論文集(書籍)内論文
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In vivo transfection of a cis element 'decoy' against signal transducers and activators of transcription 6 (STAT6)-binding site ameliorates IgE-mediated late-phase reaction in an atopic dermatitis mouse model
H. Yokozeki, M. H. Wu, K. Sumi, K. Awad, T. Satoh, I. Katayama, K. Takeda, S. Akira, Y. Kaneda, K. Nishioka
Gene Therapy Vol. 11 No. 24 p. 1753-1762 2004年12月 研究論文(学術雑誌)
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In vivo transfection of a cis element 'decoy' against signal transducers and activators of the transcription 6 (STAT6) binding site ameliorates the response of contact hypersensitivity
K. Sumi, H. Yokozeki, M. H. Wu, T. Satoh, Y. Kaneda, K. Takeda, S. Akira, K. Nishioka
Gene Therapy Vol. 11 No. 24 p. 1763-1771 2004年12月 研究論文(学術雑誌)
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Cytoprotection by bcl-2 gene transfer against ischemic liver injuries together with repressed lipid peroxidation and increased ascorbic acid in livers and serum
S Yanada, Y Saitoh, Y Kaneda, N Miwa
JOURNAL OF CELLULAR BIOCHEMISTRY Vol. 93 No. 5 p. 857-870 2004年11月 研究論文(学術雑誌)
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Somatic gene targeting with RNA/DNA chimeric oligonucleotides: an analysis with a sensitive reporter mouse system
A Ino, S Yamamoto, Y Kaneda, Kobayashi, I
JOURNAL OF GENE MEDICINE Vol. 6 No. 11 p. 1272-1280 2004年11月 研究論文(学術雑誌)
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Application of decoy oligodeoxynucleotides-based approach to renal diseases
N Tomita, H Azuma, Y Kaneda, T Ogihara, R Morishita
CURRENT DRUG TARGETS Vol. 5 No. 8 p. 717-733 2004年11月
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Subcellular trafficking of exogenously expressed interferon-beta in Madin-Darby canine kidney cells
M Maruyama, T Nishio, T Kato, T Yoshida, C Ishida, Y Watanabe, M Nishikawa, Y Kaneda, Y Takakura
JOURNAL OF CELLULAR PHYSIOLOGY Vol. 201 No. 1 p. 117-125 2004年10月 研究論文(学術雑誌)
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Enhanced tumor-specific long-term immunity of hemaggluttinating virus of Japan-mediated dendritic cell-tumor fused cell vaccination-by coadministration with CpG oligodeoxynucleotides
K Hiraoka, S Yamamoto, S Otsuru, S Nakai, K Tamai, R Morishita, T Ogihara, Y Kaneda
JOURNAL OF IMMUNOLOGY Vol. 173 No. 7 p. 4297-4307 2004年10月 研究論文(学術雑誌)
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Safety evaluation of clinical gene therapy using hepatocyte growth factor to treat peripheral arterial disease.
森下竜一
Hypertension 2004年9月 研究論文(学術雑誌)
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Alteration of the timing of implantation by in vivo gene transfer: delay of implantation by suppression of nuclear factor kappa B activity and partial rescue by leukemia inhibitory factor
H Nakamura, T Kimura, K Ogita, S Koyama, T Tsujie, T Tsutsui, K Shimoya, M Koyama, Y Kaneda, Y Murata
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS Vol. 321 No. 4 p. 886-892 2004年9月 研究論文(学術雑誌)
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Periostin as a novel factor responsible for ventricular dilation
N Katsuragi, R Morishita, N Nakamura, T Ochiai, Y Taniyama, Y Hasegawa, K Kawashima, Y Kaneda, T Ogihara, K Sugimura
CIRCULATION Vol. 110 No. 13 p. 1806-1813 2004年9月 研究論文(学術雑誌)
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Effective accumulation of poly(vinylpyrrolidone-co-vinyl laurate) into the spleen
Y Yoshioka, Y Tsutsumi, Y Mukai, H Shibata, T Okamoto, Y Kaneda, S Tsunoda, H Kamada, K Koizumi, Y Yamamoto, Y Mu, H Kodaira, K Sato-Kamada, S Nakagawa, T Mayumi
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A Vol. 70A No. 2 p. 219-223 2004年8月 研究論文(学術雑誌)
-
Safety evaluation of clinical gene therapy using hepatocyte growth factor to treat peripheral arterial disease.
森下竜一
Hypertension 2004年8月 研究論文(学術雑誌)
-
Safety evaluation of clinical gene therapy using hepatocyte growth factor to treat peripheral arterial disease
R Morishita, M Aoki, N Hashiya, H Makino, K Yamasaki, J Azuma, Y Sawa, H Matsuda, Y Kaneda, T Ogihara
HYPERTENSION Vol. 44 No. 2 p. 203-209 2004年8月 研究論文(学術雑誌)
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Hemagglutinating virus of Japan protein is efficient for induction of CD4(+) T-cell response by a hepatitis B core particle-based HIV vaccine
S Takeda, K Shiosaki, Y Kaneda, T Nakasatomi, H Yoshizaki, K Someya, Y Konno, Y Eda, Y Kino, N Yamamoto, M Honda
CLINICAL IMMUNOLOGY Vol. 112 No. 1 p. 92-105 2004年7月 研究論文(学術雑誌)
-
Transcription factor decoy for AP-1 reduces mesangial cell proliferation and extracellular matrix production in vitro and in vivo
JD Ahn, R Morishita, Y Kaneda, HJ Kim, YD Kim, HJ Lee, KU Lee, JY Park, YH Kim, KK Park, YC Chang, KH Yoon, HS Kwon, KG Park, IK Lee
GENE THERAPY Vol. 11 No. 11 p. 916-923 2004年6月 研究論文(学術雑誌)
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Inhibition of experimental abdominal aortic aneurysm in the rat by use of decoy oligodeoxynucleotides suppressing activity of nuclear factor kappaB and ets transcription factors.
Nakashima H
Circulation 2004年6月 研究論文(学術雑誌)
-
In vivo evidence of angiogenesis induced by transcription factor ets-1 - Ets-1 is located upstream of angiogenesis cascade
N Hashiya, N Jo, M Aoki, K Matsumoto, T Nakamura, Y Sato, N Ogata, T Ogihara, Y Kaneda, R Morishita
CIRCULATION Vol. 109 No. 24 p. 3035-3041 2004年6月 研究論文(学術雑誌)
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Enhanced therapeutic angiogenesis by cotransfection of prostacyclin synthase gene or optimization of intramusclular injection of naked plasmid DNA
Hiraoka, K, Koike, H, Yamamoto, S, Tomita, N, Yokoyama, C, Tanabe, T, Aikou, T, Ogihara, T, Kaneda, Y, Morishita, R
Circulation 2004年6月 研究論文(学術雑誌)
-
Essential role of HGF (hepatocyte growth factor) in blood formation in Xenopus.
Koibuchi, N, Kaneda, Y, Taniyama, Y, Matsumoto, K, Nakamura, T, Ogihara, T, Morishita, R
Blood 2004年6月 研究論文(学術雑誌)
-
In vivo evidence of angiogenesis induced by transcription factor ets-1 - Ets-1 is located upstream of angiogenesis cascade
N Hashiya, N Jo, M Aoki, K Matsumoto, T Nakamura, Y Sato, N Ogata, T Ogihara, Y Kaneda, R Morishita
CIRCULATION Vol. 109 No. 24 p. 3035-3041 2004年6月 研究論文(学術雑誌)
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The HVJ-envelope as an innovative vector system for cardiovascular disease
H Kotani, T Nakajima, SP Lai, R Morishita, Y Kaneda
CURRENT GENE THERAPY Vol. 4 No. 2 p. 183-194 2004年6月
-
Lack of association between the hepatocyte growth factor receptor, c-met, and the anti-apoptotic action of bag-1 in endothelial cells
H Nakagami, R Morishita, T Nishikawa, H Shimizu, S Iguchi, K Matsumoto, T Nakamura, Y Kaneda, T Ogihara
HYPERTENSION RESEARCH Vol. 27 No. 5 p. 359-365 2004年5月 研究論文(学術雑誌)
-
Gene therapy with an E2F transcription factor decoy inhibits cell cycle progression in rat anti-Thy 1 glomerulonephritis
N Tomita, JYS Kim, GH Gibbons, LN Zhang, Y Kaneda, RAK Stahl, M Ogborn, B Venderville, R Morishita, D Baran, VJ Dzau
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE Vol. 13 No. 5 p. 629-636 2004年5月 研究論文(学術雑誌)
-
Transposon-independent increase of transcription by the Sleeping Beauty transposase
K Masuda, S Yamamoto, M Endoh, Y Kaneda
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS Vol. 317 No. 3 p. 796-800 2004年5月 研究論文(学術雑誌)
-
Lack of association between the hepatocyte growth factor receptor, c-met, and the anti-apoptotic action of bag-1 in endothelial cells
H Nakagami, R Morishita, T Nishikawa, H Shimizu, S Iguchi, K Matsumoto, T Nakamura, Y Kaneda, T Ogihara
HYPERTENSION RESEARCH Vol. 27 No. 5 p. 359-365 2004年5月 研究論文(学術雑誌)
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【皮膚科医のための臨床トピックス】遺伝子治療の現状 おとり型核酸医薬など
玉井 克人, 金田 安史, 中邨 弘重, 森下 竜一, 中野 創, 花田 勝美, 板見 智, 片山 一郎
臨床皮膚科 Vol. 58 No. 5 p. 171-174 2004年4月
出版者・発行元:(株)医学書院
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Molecular therapy to inhibit NF kappa B activation by transcription factor decoy oligonucleotides
R Morishita, N Tomita, Y Kaneda, T Ogihara
CURRENT OPINION IN PHARMACOLOGY Vol. 4 No. 2 p. 139-146 2004年4月
-
Local delivery of E2F decoy oligodeoxynucleotides using ultrasound with microbubble agent (Optison) inhibits intimal hyperplasia after balloon injury in rat carotid artery model
N Hashiya, M Aoki, K Tachibana, Y Taniyama, K Yamasaki, K Hiraoka, H Makino, K Yasufumi, T Ogihara, R Morishita
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS Vol. 317 No. 2 p. 508-514 2004年4月 研究論文(学術雑誌)
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医学研究者,医療者における様々な遺伝子診断に対する意識調査
駒沢 伸泰, 村岡 潔, 玉井 克人, 金田 安史, 森本 兼嚢
日本遺伝カウンセリング学会誌 Vol. 25 No. 1 p. 41-41 2004年3月
出版者・発行元:(一社)日本遺伝カウンセリング学会
-
Lamr1 functional retroposon causes right ventricular dysplasia in mice
Y Asano, S Takashima, M Asakura, Y Shintani, YL Liao, T Minamino, H Asanuma, S Sanada, J Kim, A Ogai, T Fukushima, Y Oikawa, Y Okazaki, Y Kaneda, M Sato, J Miyazaki, S Kitamura, H Tomoike, M Kitakaze, M Hori
NATURE GENETICS Vol. 36 No. 2 p. 123-130 2004年2月 研究論文(学術雑誌)
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No influence of tumor growth by intramuscular injection of hepatocyte growth factor plasmid DNA: safety evaluation of therapeutic angiogenesis gene therapy in mice
A Matsuki, S Yamamoto, H Nakagami, M Aoki, K Tamai, K Matsumoto, T Nakamura, T Ogihara, Y Kaneda, R Morishita
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS Vol. 315 No. 1 p. 59-65 2004年2月 研究論文(学術雑誌)
-
Delivery of siRNA using HVJ envelope vector
Yasufumi Kaneda
Drug Delivery System Vol. 19 No. 4 p. 379-384 2004年 研究論文(学術雑誌)
-
Hepatocyte growth factor both prevents and ameliorates the symptoms of dermal sclerosis in a mouse model of scleroderma
M. H. Wu, H. Yokozeki, S. Takagawa, T. Yamamoto, T. Satoh, Y. Kaneda, I. Katayama, K. Nishioka
Gene Therapy Vol. 11 No. 2 p. 170-180 2004年1月 研究論文(学術雑誌)
-
Novel (recombinant BCG- and DNA-) vaccination against tuberculosis using cynomolgus monkey
Kita, I, T Tanaka, S Yoshida, N Ohara, Y Kaneda, Kuwayama, I, Muraki, I, Kanamaru, I, S Hashimoto, H Takai, C Okada, Y Fukunaga, Y Sakaguchi, Furukawa, I, K Yamada, Inoue, I, Takemoto, I, M Naito, T Yamada, M Matsumoto, EC Cruz, EV Tan, RM Abalos, LJ Young, JA Burgos, R Gelber, Y Skeiky, S Reed, M Sakatani, M Okada
IMMUNOLOGY 2004: IMMUNODEFICIENCY, INFECTIOUS DISEASES, IMMUNOMODULATION, AND VACCINES p. 403-406 2004年 研究論文(国際会議プロシーディングス)
-
Inhibition of neointimal hyperplasia after balloon injury by cis-element 'decoy' of early growth response gene-1 in hypercholesterolemic rabbits
K Ohtani, K Egashira, M Usui, M Ishibashi, KI Hiasa, Q Zhao, M Aoki, Y Kaneda, R Morishita, A Takeshita
GENE THERAPY Vol. 11 No. 2 p. 126-132 2004年1月 研究論文(学術雑誌)
-
Intrathecal injection of HVJ-E containing HGF gene to cerebrospinal fluid can prevent and ameliorate hearing impairment in rats
K Oshima, M Shimamura, S Mizuno, K Tamai, K Doi, R Morishita, T Nakamura, T Kubo, Y Kaneda
FASEB JOURNAL Vol. 18 No. 1 p. 212-214 2004年1月 研究論文(学術雑誌)
-
Inhibition of experimental abdominal aortic aneurysm in the rat by use of decoy oligodeoxynucleotides suppressing activity of nuclear factor kappa B and ets transcription factors
H Nakashima, M Aoki, T Miyake, T Kawasaki, M Iwai, N Jo, M Oishi, K Kataoka, S Ohgi, T Ogihara, Y Kaneda, R Morishita
CIRCULATION Vol. 109 No. 1 p. 132-138 2004年1月 研究論文(学術雑誌)
-
Novel therapeutic strategy to treat brain ischemia - Overexpression of hepatocyte growth factor gene reduced ischemic injury without cerebral edema in rat model
M Shimamura, N Sato, K Oshima, M Aoki, H Kurinami, S Waguri, Y Uchiyama, T Ogihara, Y Kaneda, R Morishita
CIRCULATION Vol. 109 No. 3 p. 424-431 2004年1月 研究論文(学術雑誌)
-
Intramuscular gene transfer of interleukin-10 cDNA reduces atherosclerosis in apolipoprotein E-knockout mice
M Namiki, S Kawashima, T Yamashita, M Ozaki, T Sakoda, N Inoue, KI Hirata, R Morishita, Y Kaneda, M Yokoama
ATHEROSCLEROSIS Vol. 172 No. 1 p. 21-29 2004年1月 研究論文(学術雑誌)
-
[Gene transfer with ultrasound and microbubbles (optison) as a potential treatment for cardiovascular diseases].
Taniyama Y, Tomita N, Endoh S, Kaneda Y, Ogihara T, Morishita R
Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics Vol. 41 No. 1 p. 51-54 2004年1月
出版者・発行元:The Japan Geriatrics Society
-
Egr-1 in vascular smooth muscle cell proliferation in response to allo-antigen
Y Wada, M Fujimori, J Suzuki, K Tsukioka, K Ito, Y Sawa, R Morishita, Y Kaneda, M Isobe, J Amano
JOURNAL OF SURGICAL RESEARCH Vol. 115 No. 2 p. 294-302 2003年12月 研究論文(学術雑誌)
-
Enhanced therapeutic angiogenesis by cotransfection of prostacyclin synthase gene or optimization of intramuscular injection of naked plasmid DNA
K Hiraoka, H Koike, S Yamamoto, N Tomita, C Yokoyama, T Tanabe, T Aikou, T Ogihara, Y Kaneda, R Morishita
CIRCULATION Vol. 108 No. 21 p. 2689-2696 2003年11月 研究論文(学術雑誌)
-
Angiogenesis induced by endothelial nitric oxide synthase gene through vascular endothelial growth factor expression in a rat hindlimb ischemia model
T Namba, H Koike, K Murakami, M Aoki, H Makino, N Hashiya, T Ogihara, Y Kaneda, M Kohno, R Morishita
CIRCULATION Vol. 108 No. 18 p. 2250-2257 2003年11月 研究論文(学術雑誌)
-
New vector innovation for drug delivery: Development of fusigenic non-viral particles
Y Kaneda
CURRENT DRUG TARGETS Vol. 4 No. 8 p. 599-602 2003年11月
-
Mice with defects in HB-EGF ectodomain shedding show severe developmental abnormalities
S Yamazaki, R Iwamoto, K Saeki, M Asakura, S Takashima, A Yamazaki, R Kimura, H Mizushima, H Moribe, S Higashiyama, M Endoh, Y Kaneda, S Takagi, S Itami, N Takeda, G Yamada, E Mekada
JOURNAL OF CELL BIOLOGY Vol. 163 No. 3 p. 469-475 2003年11月 研究論文(学術雑誌)
-
Ribosomal proteins S0 and S21 are involved in the stability of 18S rRNA in fission yeast, Schizosaccharomyces pombe
M Sato, CJ Kong, H Yoshida, T Nakamura, A Wada, C Shimoda, Y Kaneda
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS Vol. 311 No. 4 p. 942-947 2003年11月 研究論文(学術雑誌)
-
Highly efficient and minimally invasive in-vivo gene transfer to the mouse uterus using haemagglutinating virus of Japan (HVJ) envelope vector
H Nakamura, T Kimura, H Ikegami, K Ogita, S Koyama, K Shimoya, T Tsujie, M Koyama, Y Kaneda, Y Murata
MOLECULAR HUMAN REPRODUCTION Vol. 9 No. 10 p. 603-609 2003年10月 研究論文(学術雑誌)
-
Inhibition of inducible NF-kappa B activity reduces chemoresistance to 5-fluorouracil in human stomach cancer cell line
H Uetsuka, M Haisa, M Kimura, M Gunduz, Y Kaneda, T Ohkawa, M Takaoka, T Murata, T Nobuhisa, T Yamatsuji, J Matsuoka, N Tanaka, Y Naomoto
EXPERIMENTAL CELL RESEARCH Vol. 289 No. 1 p. 27-35 2003年9月 研究論文(学術雑誌)
-
[Gene therapy for colorectal cancer in clinical trials].
Hiraoka K, Kaneda Y
Nihon rinsho. Japanese journal of clinical medicine Vol. 61 Suppl 7 p. 522-525 2003年9月
-
Nuclear factor kappa B decoy oligodeoxynucleotides prevent endotoxin-induced fatal liver failure in a murine model
Ogushi, I, Y Iimuro, E Seki, G Son, T Hirano, T Hada, H Tsutsui, K Nakanishi, R Morishita, Y Kaneda, J Fujimoto
HEPATOLOGY Vol. 38 No. 2 p. 335-344 2003年8月 研究論文(学術雑誌)
-
非ウイルスベクターによる細胞標的法の開発
冨田 奈留也, 森下 竜一, 金田 安史
炎症・再生 : 日本炎症・再生医学会雑誌 = Inflammation and regeneration Vol. 23 No. 3 p. 170-174 2003年5月10日
出版者・発行元:The Japanese Society of Inflammation and Regeneration
-
Efficient gene transfer from innervated muscle into rat peripheral and central nervous systems using a non-viral haemagglutinating virus of Japan (HVJ)-liposome method
N Kato, K Nakanishi, K Nemoto, R Morishita, Y Kaneda, M Uenoyama, T Ikeda, K Fujikawa
JOURNAL OF NEUROCHEMISTRY Vol. 85 No. 3 p. 810-815 2003年5月 研究論文(学術雑誌)
-
Gene therapy with transcription factor decoy oligonucleotides as a potential treatment for cardiovascular diseases
N Tomita, H Azuma, Y Kaneda, T Ogihara, R Morishita
CURRENT DRUG TARGETS Vol. 4 No. 4 p. 339-346 2003年5月
-
Genomic organization and promoter analysis of the Dnmt3b gene
C Ishida, K Ura, A Hirao, H Sasaki, A Toyoda, Y Sakaki, H Niwa, E Li, Y Kaneda
GENE Vol. 310 p. 151-159 2003年5月 研究論文(学術雑誌)
-
Suppression of oxidative stress-induced hepatocyte injury by calpain antisense
K Taniguchi, K Umeshita, M Sakon, H Miyoshi, M Tokunaga, H Ariyoshi, T Yamano, Y Kaneda, M Monden
JOURNAL OF SURGICAL RESEARCH Vol. 111 No. 1 p. 23-27 2003年5月 研究論文(学術雑誌)
-
先天性表皮水疱症 遺伝子治療法の開発
玉井 克人, 菊池 康, 花田 勝美, 小川 秀興, 金田 安史
日本皮膚科学会雑誌 Vol. 113 No. 4 p. 462-462 2003年4月
出版者・発行元:(公社)日本皮膚科学会
-
Current status and future prospects of gene therapy technologies toward the treatment of intractable skin diseases
Yasufumi Kaneda, Katsuto Tamai
Archives of Dermatological Research, Supplement Vol. 295 No. 1 p. S63-S66 2003年4月 研究論文(学術雑誌)
-
Current status and future prospects of gene therapy technologies toward the treatment of intractable skin diseases
Y Kaneda, K Tamai
ARCHIVES OF DERMATOLOGICAL RESEARCH Vol. 295 p. S63-S66 2003年4月 研究論文(学術雑誌)
-
【アトピー性皮膚炎・蕁麻疹の治療ガイド】新規アトピー性皮膚炎治療薬の開発 転写因子NFκBを標的としたODNの臨床応用
玉井 克人, 森下 竜一, 中邨 弘重, 千葉 容子, 金田 安史, 花田 勝美
アレルギーの臨床 Vol. 23 No. 3 p. 196-201 2003年3月
出版者・発行元:(株)北隆館
-
Antisense in vivo knockdown of synaptotagmin I and synapsin I by HVJ-liposome mediated gene transfer modulates ischemic injury of hippocampus in opposing ways
M Iwakuma, T Anzai, S Kobayashi, M Ogata, Y Kaneda, K Ohno, M Saji
NEUROSCIENCE RESEARCH Vol. 45 No. 3 p. 285-296 2003年3月 研究論文(学術雑誌)
-
A novel combination of suicide gene therapy and histone deacetylase inhibitor for treatment of malignant melanoma
S Yamamoto, T Yamano, M Tanaka, DSB Hoon, S Takao, R Morishita, T Aikou, Y Kaneda
CANCER GENE THERAPY Vol. 10 No. 3 p. 179-186 2003年3月 研究論文(学術雑誌)
-
Angiogenic property of hepatocyte growth factor is dependent on Upregulation of essential transcription factor for angiogenesis, ets-1
N Tomita, R Morishita, Y Taniyama, H Koike, M Aoki, H Shimizu, K Matsumoto, T Nakamura, Y Kaneda, T Ogihara
CIRCULATION Vol. 107 No. 10 p. 1411-1417 2003年3月 研究論文(学術雑誌)
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【アレルギー性疾患の特殊な治療の現状と展望】アトピー性皮膚炎に対する核酸医薬導入による新しい治療法
玉井 克人, 森下 竜一, 中邨 広重, 金田 安史, 花田 勝美
アレルギー・免疫 Vol. 10 No. 3 p. 349-356 2003年2月
出版者・発行元:(株)医薬ジャーナル社
-
Gene therapy for ischemic brain diseases.
Saitoh Y, Kato A, Hagihara Y, Kaneda Y, Yoshimine T
Current gene therapy Vol. 3 No. 1 p. 49-58 2003年2月
-
Enhanced angiogenesis and improvement of neuropathy by cotransfection of human hepatocyte growth factor and prostacyclin synthase gene
H Koike, R Morishita, S Iguchi, M Aoki, K Matsumoto, T Nakamura, C Yokoyama, T Tanabe, T Ogihara, Y Kaneda
FASEB JOURNAL Vol. 17 No. 2 p. 779-+ 2003年2月 研究論文(学術雑誌)
-
HGF/NK4 inhibited VEGF-induced angiogenesis in in vitro cultured endothelial cells and in vivo rabbit model.
Nakabayashi M, Morishita R, Nakagami H, Kuba K, Matsumoto K, Nakamura T, Tano Y, Kaneda Y, Diabetologia, v
Vol. 46 No. 1 p. 115-123 2003年1月
-
HVJ-envelope vector for gene transfer into central nervous system
M Shimamura, R Morishita, M Endoh, K Oshima, M Aoki, S Waguri, Y Uchiyama, Y Kaneda
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS Vol. 300 No. 2 p. 464-471 2003年1月 研究論文(学術雑誌)
-
Genetic modification of cold-preserved renal grafts using HSP70 or bcl-2 HVJ-liposome method
J Kita, E Kobayashi, A Hishinuma, Y Kaneda
TRANSPLANT IMMUNOLOGY Vol. 11 No. 1 p. 7-14 2003年1月 研究論文(学術雑誌)
-
Therapeutic potential of oligonucleotide-based therapy in cardiovascular disease
R Morishita, Y Kaneda, T Ogihara
BIODRUGS Vol. 17 No. 6 p. 383-389 2003年
-
The Hemagglutinating Virus of Japan-Liposome Method for Gene Delivery
Yasufumi Kaneda, Seiji Yamamoto, Kazuya Hiraoka
LIPOSOMES, PT C Vol. 373 p. 482-493 2003年 論文集(書籍)内論文
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Novel E2F decoy oligodeoxynucleotides inhibit in vitro vascular smooth muscle cell proliferation and in vivo neointimal hyperplasia
JD Ahn, R Morishita, Y Kaneda, HS Kim, YC Chang, KU Lee, JY Park, HW Lee, YH Kim, IK Lee
GENE THERAPY Vol. 9 No. 24 p. 1682-1692 2002年12月 研究論文(学術雑誌)
-
Synaptotagmin I hypothalamic knockdown prevents amygdaloid seizure-induced damage of hippocampal neurons but not of entorhinal neurons
S Kobayashi, K Ohno, M Iwakuma, Y Kaneda, M Saji
NEUROSCIENCE RESEARCH Vol. 44 No. 4 p. 455-465 2002年12月 研究論文(学術雑誌)
-
Tissue factor pathway inhibitor gene delivery using HVJ-AVE liposomes markedly reduces restenosis in atherosclerotic arteries
XH Yin, C Yutani, Y Ikeda, K Enjyoji, H Ishibashi-Ueda, S Yasuda, Y Tsukamoto, H Nonogi, Y Kaneda, H Kato
CARDIOVASCULAR RESEARCH Vol. 56 No. 3 p. 454-463 2002年12月 研究論文(学術雑誌)
-
Expression of matrix metalloproteinases in cardiac allograft vasculopathy and its attenuation by anti MMP-2 ribozyme gene transfection
K Tsukioka, J Suzuki, M Fujimori, Y Wada, K Yamaura, K Ito, R Morishita, Y Kaneda, M Isobe, J Amano
CARDIOVASCULAR RESEARCH Vol. 56 No. 3 p. 472-478 2002年12月 研究論文(学術雑誌)
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Gene transfer of human hepatocyte growth factor into rat skin wounds mediated by liposomes coated with the Sendai virus (hemagglutinating virus of Japan)
K Nakanishi, M Uenoyama, N Tomita, R Morishita, Y Kaneda, T Ogihara, K Matsumoto, T Nakamura, K Maruta, S Matsuyama, T Kawai, T Aurues, T Hayashi, T Ikeda
AMERICAN JOURNAL OF PATHOLOGY Vol. 161 No. 5 p. 1761-1772 2002年11月 研究論文(学術雑誌)
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Targeted gene therapy for rat glomerulonephritis using HVJ-immunoliposomes
N Tomita, R Morishita, K Yamamoto, J Higaki, VJ Dzau, T Ogihara, Y Kaneda
JOURNAL OF GENE MEDICINE Vol. 4 No. 5 p. 527-535 2002年9月 研究論文(学術雑誌)
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Human cytomegalovirus immediate-early protein IE2-86, but not IE1-72, causes graft coronary arteriopathy in the transplanted rat heart
K Suzuki, B Murtuza, N Suzuki, M Khan, Y Kaneda, MH Yacoub
CIRCULATION Vol. 106 No. 13 p. I158-I162 2002年9月 研究論文(学術雑誌)
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In vivo gene transfection with hepatocyte growth factor via the pulmonary artery induces angiogenesis in the rat lung
M Ono, Y Sawa, K Matsumoto, T Nakamura, Y Kaneda, H Matsuda
CIRCULATION Vol. 106 No. 13 p. I264-I269 2002年9月 研究論文(学術雑誌)
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Heat shock protein 72 enhances manganese superoxide dismutase activity during myocardial ischemia-reperfusion injury, associated with myocardial protection and apoptosis reduction
K Suzuki, B Murtuza, IA Sammut, N Latif, J Jayakumar, RT Smolenski, Y Kaneda, Y Sawa, H Matsuda, MH Yacoub
CIRCULATION Vol. 106 No. 13 p. I270-I276 2002年9月 研究論文(学術雑誌)
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転写因子NFkBを標的としたdecoy oligo deoxynucleotides(ODN)による新規アトピー性皮膚炎治療薬の開発と臨床応用
玉井 克人, 森下 竜一, 千葉 容子, 中邨 弘重, 金子 高英, 水木 大介, 原田 研, 中野 創, 金田 安史, 花田 勝美
日本研究皮膚科学会年次学術大会・総会プログラム Vol. 27回 p. 104-104 2002年8月
出版者・発行元:(一社)日本研究皮膚科学会
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クロマチン 生命情報発現の拠点 発生分化に伴うクロマチン構造変換とDNAのメチル化
浦 聖恵, 佐伯 英昭, 石田 智咲, 柏木 克信, 森田 奈亜子, 金田 安史
生化学 Vol. 74 No. 8 p. 651-651 2002年8月
出版者・発行元:(公社)日本生化学会
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Therapeutic approach to familial hypercholesterolemia by HVJ-liposomes in LDL receptor knockout mouse
N Tomita, R Morishita, H Koike, M Hashizume, M Notake, B Fujitani, Y Kaneda, M Horiuchi, T Ogihara
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE Vol. 10 No. 2 p. 137-143 2002年8月 研究論文(学術雑誌)
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Hepatocyte growth factor prevents endothelial cell death through inhibition of bax translocation from cytosol to mitochondrial membrane
H Nakagami, R Morishita, K Yamamoto, Y Taniyama, M Aoki, K Yamasaki, K Matsumoto, T Nakamura, Y Kaneda, T Ogihara
DIABETES Vol. 51 No. 8 p. 2604-2611 2002年8月 研究論文(学術雑誌)
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Hemagglutinating virus of Japan (HVJ) envelope vector as a versatile gene delivery system
Y Kaneda, T Nakajima, T Nishikawa, S Yamamoto, H Ikegami, N Suzuki, H Nakamura, R Morishita, H Kotani
MOLECULAR THERAPY Vol. 6 No. 2 p. 219-226 2002年8月 研究論文(学術雑誌)
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Angiogenesis and antifibrotic action by hepatocyte growth factor in cardiomyopathy
Y Taniyama, R Morishita, M Aoki, K Hiraoka, K Yamasaki, N Hashiya, K Matsumoto, T Nakamura, Y Kaneda, T Ogihara
HYPERTENSION Vol. 40 No. 1 p. 47-53 2002年7月 研究論文(学術雑誌)
-
Inhibitory effects of novel AP-1 decoy oligodeoxynucleotides on vascular smooth muscle cell proliferation in vitro and neointimal formation in vivo
JD Ahn, R Morishita, Y Kaneda, SJ Lee, KY Kwon, SY Choi, KU Lee, JY Park, IJ Moon, JG Park, M Yoshizumi, Y Ouchi, IK Lee
CIRCULATION RESEARCH Vol. 90 No. 12 p. 1325-1332 2002年6月 研究論文(学術雑誌)
-
Transluminal gene transfer into brain capillary endothelial cells in vivo with HVJ-liposomes
C Jiang, H Matsuo, N Koyabu, H Ohtani, H Fujimoto, Y Yonemitsu, Y Kaneda, M Naito, T Tsuruo, Y Sawada
JOURNAL OF DRUG TARGETING Vol. 10 No. 4 p. 345-352 2002年6月 研究論文(学術雑誌)
-
Effective transfection of a cis element "decoy" of the nuclear factor-kappa B binding site into the experimental choroidal neovascularization
N Jo, N Ogata, M Aoki, T Otsuji, R Morishita, Y Kaneda, M Matsumura
CURRENT EYE RESEARCH Vol. 24 No. 6 p. 465-473 2002年6月 研究論文(学術雑誌)
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高齢者閉塞性動脈硬化症に対するHGF遺伝子プラスミドを用いた血管新生療法の検討
若山 幸示, 森下 竜一, 青木 元邦, 山崎 慶太, 牧野 寛史, 橋弥 尚孝, 東 純哉, 村上 和司, 金田 安史, 荻原 俊男
日本老年医学会雑誌 Vol. 39 No. Suppl. p. 89-89 2002年5月
出版者・発行元:(一社)日本老年医学会
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Fetal gene transfer by intrauterine injection with microbubble-enhanced ultrasound
M Endoh, N Koibuchi, M Sato, R Morishita, T Kanzaki, Y Murata, Y Kaneda
MOLECULAR THERAPY Vol. 5 No. 5 p. 501-508 2002年5月 研究論文(学術雑誌)
-
Gene transfer of hepatocyte growth factor to subarachnoid space in cerebral hypoperfusion model
S Yoshimura, R Morishita, K Hayashi, J Kokuzawa, M Aoki, K Matsumoto, T Nakamura, T Ogihara, N Sakai, Y Kaneda
HYPERTENSION Vol. 39 No. 5 p. 1028-1034 2002年5月 研究論文(学術雑誌)
-
Molecular strategy using cis-element 'decay' of E2F binding site inhibits neointimal formation in porcine balloon-injured coronary artery model
T Nakamura, R Morishita, T Asai, N Tsuboniwa, M Aoki, H Sakonjo, K Yamasaki, N Hashiya, Y Kaneda, T Ogihara
GENE THERAPY Vol. 9 No. 8 p. 488-494 2002年4月 研究論文(学術雑誌)
-
N141I mutant Presenilin-2 gene enhances neuronal cell death and decreases bcl-2 expression
M Mori, H Nakagami, R Morishita, N Mitsuda, K Yamamoto, S Yoshimura, N Ohkubo, N Sato, T Ogihara, Y Kaneda
LIFE SCIENCES Vol. 70 No. 21 p. 2567-2580 2002年4月 研究論文(学術雑誌)
-
Induction of a systemic immune response by a polyvalent melanoma-associated antigen DNA vaccine for prevention and treatment of malignant melanoma
M Tanaka, Y Kaneda, S Fujii, T Yamano, K Hashimoto, SKS Huang, DSB Hoon
MOLECULAR THERAPY Vol. 5 No. 3 p. 291-299 2002年3月 研究論文(学術雑誌)
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Local delivery of plasmid DNA into rat carotid artery using ultrasound
Y Taniyama, K Tachibana, K Hiraoka, T Namba, K Yamasaki, N Hashiya, M Aoki, T Ogihara, K Yasufumi, R Morishita
CIRCULATION Vol. 105 No. 10 p. 1233-1239 2002年3月 研究論文(学術雑誌)
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Impairment of collateral formation in lipoprotein(a) transgenic mice - Therapeutic angiogenesis induced by human hepatocyte growth factor gene
R Morishita, M Sakaki, K Yamamoto, S Iguchi, M Aoki, K Yamasaki, K Matsumoto, T Nakamura, R Lawn, T Ogihara, Y Kaneda
CIRCULATION Vol. 105 No. 12 p. 1491-1496 2002年3月 研究論文(学術雑誌)
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遺伝子治療
金田 安史
皮膚の科学 Vol. 1 No. 1 p. 7-14 2002年
出版者・発行元:Meeting of Osaka Dermatological Association/Meeting of Keiji Dermatological Association
-
Local overexpression of monocyte chemoattractant protein-1 at vessel wall induces infiltration of macrophages and formation of atherosclerotic lesion - Synergism with hypercholesterolemia
M Namiki, S Kawashima, T Yamashita, M Ozaki, T Hirase, T Ishida, N Inoue, K Hirata, A Matsukawa, R Morishita, Y Kaneda, M Yokoyama
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY Vol. 22 No. 1 p. 115-120 2002年1月 研究論文(学術雑誌)
-
HVJ (hemagglutinating virus of Japan; Sendai virus) - Liposome method
R Morishita, Y Kaneda
GENE THERAPY METHODS Vol. 346 p. 619-627 2002年
-
Molecular therapy via transcriptional regulation with double-stranded oligodeoxynucleotides as decoys
H Nakamura, R Morishita, Y Kaneda
IN VIVO Vol. 16 No. 1 p. 45-48 2002年1月
-
Viral liposomes. Preparation and use.
Kaneda Y
Methods in molecular medicine Vol. 69 p. 63-72 2002年
-
cis element decoy against nuclear factor-kappa B attenuates development of experimental autoimmune myocarditis in rats
O Yokoseki, J Suzuki, H Kitabayashi, N Watanabe, Y Wada, M Aoki, R Morishita, Y Kaneda, T Ogihara, H Futamatsu, Y Kobayashi, M Isobe
CIRCULATION RESEARCH Vol. 89 No. 10 p. 899-906 2001年11月 研究論文(学術雑誌)
-
Novel immunotherapy for peritoneal dissemination of murine colon cancer with macrophage inflammatory protein-1 beta mediated by a tumor-specific vector, HVJ cationic liposomes
T Miyata, S Yamamoto, K Sakamoto, R Morishita, Y Kaneda
CANCER GENE THERAPY Vol. 8 No. 11 p. 852-860 2001年11月 研究論文(学術雑誌)
-
Therapeutic angiogenesis induced by human hepatocyte growth factor gene in rat diabetic hind limb ischemia model: molecular mechanisms of delayed angiogenesis in diabetes.
Taniyama Y, Morishita R, Hiraoka K, Aoki M, Nakagami H, Yamasaki K, Matsumoto K, Nakamura T, Kaneda Y, Ogihara T, Circulation
Circulation Vol. 104 No. 19 p. 2344-2350 2001年11月
-
Inhibition of intimal hyperplasia after balloon injury in rat carotid artery model using cis-element 'decoy' of nuclear factor-kappaB binding site as a novel molecular strategy.
Yoshimura S, Morishita R, Hayashi K, Yamamoto K, Nakagami H, Kaneda Y, Sakai N, Ogihara T, Gene therapy
Gene Ther Vol. 8 No. 21 p. 1635-1642 2001年11月
-
転写因子NFκBをターゲットにしたアトピー治療 NFκBデコイ含有軟膏による皮膚症状の改善
中邨 弘重, 森下 竜一, 青木 元邦, 大石 雅子, 玉井 克人, 金田 安史
日本小児アレルギー学会誌 Vol. 15 No. 4 p. 490-490 2001年9月
出版者・発行元:(一社)日本小児アレルギー学会
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Mouse macrophage metalloelastase gene delivery by HVJ-cationic liposomes in experimental antiangiogenic gene therapy for murine CT-26 colon cancer
Manuel J. Gorrin-Rivas, Shigeki Arii, Akira Mori, Yasufumi Kaneda, Masayuki Imamura
International Journal of Cancer Vol. 93 No. 5 p. 731-735 2001年9月1日 研究論文(学術雑誌)
-
Effects of gene transfection of human bcl-2 on concordant cardiac xenografts in hamster to rat model.
Kobayashi Y, Fukushima N, Sawa Y, Ohtake S, Matsumiya G, Horiguchi K, Kawaguchi N, Matsuura N, Kaneda Y, Matsuda H
The Japanese journal of thoracic and cardiovascular surgery : official publication of the Japanese Association for Thoracic Surgery = Nihon Kyobu Geka Gakkai zasshi Vol. 49 No. 9 p. 570-575 2001年9月
-
Inhibition of neointimal formation after balloon injury by cilostazol, accompanied by improvement of endothelial dysfunction and induction of hepatocyte growth factor in rat diabetes model
M Aoki, R Morishita, S Hayashi, N Jo, K Matsumoto, T Nakamura, Y Kaneda, T Ogihara
DIABETOLOGIA Vol. 44 No. 8 p. 1034-1042 2001年8月 研究論文(学術雑誌)
-
Gene therapy for preventing neuronal death using hepatocyte growth factor: in vivo gene transfer of HGF to subarachnoid space prevents delayed neuronal death in gerbil hippocampal CA1 neurons.
Hayashi K, Morishita R, Nakagami H, Yoshimura S, Hara A, Matsumoto K, Nakamura T, Ogihara T, Kaneda Y, Sakai N, Gene therapy
Gene Ther Vol. 8 No. 15 p. 1167-1173 2001年8月
-
Leptin Induces Mitochondrial Superoxide Production and Monocyte Chemoattractant Protein-1 Expression in Aortic Endothelial Cells by Increasing Fatty Acid Oxidation via Protein Kinase A
Sho-Ichi Yamagishi, Diane Edelstein, Xue-Liang Du, Yasufumi Kaneda, Manuel Guzmán, Michael Brownlee
Journal of Biological Chemistry Vol. 276 No. 27 p. 25096-25100 2001年7月6日 研究論文(学術雑誌)
-
Endothelial apoptosis induced by oxidative stress through activation of NF-kappaB: antiapoptotic effect of antioxidant agents on endothelial cells.
Aoki M, Nata T, Morishita R, Matsushita H, Nakagami H, Yamamoto K, Yamazaki K, Nakabayashi M, Ogihara T, Kaneda Y, Hypertension, Dallas, Te
Hypertension Vol. 38 No. 1 p. 48-55 2001年7月
-
EBV replicon vector system enhances transgene expression in vivo: applications to cancer gene therapy.
Otomo T, Yamamoto S, Morishita R, Kaneda Y
The journal of gene medicine Vol. 3 No. 4 p. 345-352 2001年7月
-
Transcription factor decoy for activator protein-1 (AP-1) inhibits high glucose- and angiotensin II-induced type 1 plasminogen activator inhibitor (PAI-1) gene expression in cultured human vascular smooth muscle cells
JD Ahn, R Morishita, Y Kaneda, KU Lee, JY Park, YJ Jeon, HS Song, IK Lee
DIABETOLOGIA Vol. 44 No. 6 p. 713-720 2001年6月 研究論文(学術雑誌)
-
Intravenous injection of oligodeoxynucleotides to the NF-kappaB binding site inhibits hepatic metastasis of M5076 reticulosarcoma in mice
Kawamura, I, R Morishita, S Tsujimoto, T Manda, M Tomoi, N Tomita, T Goto, T Ogihara, Y Kaneda
GENE THERAPY Vol. 8 No. 12 p. 905-912 2001年6月 研究論文(学術雑誌)
-
Hepatocyte growth factor ameliorates acute graft-versus-host disease and promotes hematopoietic function
T Kuroiwa, E Kakishita, T Hamano, Y Kataoka, Y Seto, N Iwata, Y Kaneda, K Matsumoto, T Nakamura, T Ueki, J Fujimoto, T Iwasaki
JOURNAL OF CLINICAL INVESTIGATION Vol. 107 No. 11 p. 1365-1373 2001年6月 研究論文(学術雑誌)
-
Phosphorylation of p38 mitogen-activated protein kinase downstream of bax-caspase-3 pathway leads to cell death induced by high D-glucose in human endothelial cells.
Nakagami H, Morishita R, Yamamoto K, Yoshimura SI, Taniyama Y, Aoki M, Matsubara H, Kim S, Kaneda Y, Ogihara T, Diabetes
Diabetes Vol. 50 No. 6 p. 1472-1481 2001年6月
-
Contribution of Bcl-2, but not Bcl-xL and Bax, to antiapoptotic actions of hepatocyte growth factor in hypoxia-conditioned human endothelial cells.
Yamamoto K, Morishita R, Hayashi S, Matsushita H, Nakagami H, Moriguchi A, Matsumoto K, Nakamura T, Kaneda Y, Ogihara T, Hypertension, Dallas, Te
Vol. 37 No. 5 p. 1341-1348 2001年5月 研究論文(学術雑誌)
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Prolonged transgene expression in glomeruli using an EBV replicon vector system combined with HVJ liposomes
M Tsujie, Y Isaka, H Nakamura, Y Kaneda, E Imai, M Hori
KIDNEY INTERNATIONAL Vol. 59 No. 4 p. 1390-1396 2001年4月 研究論文(学術雑誌)
-
ATP-dependent chromatin remodeling facilitates nucleotide excision repair of UV-induced DNA lesions in synthetic dinucleosomes
Kiyoe Ura, Marito Araki, Hideaki Saeki, Chikahide Masutani, Takashi Ito, Shigenori Iwai, Toshimi Mizukoshi, Yasufumi Kaneda, Fumio Hanaoka
EMBO Journal Vol. 20 2001年4月 研究論文(学術雑誌)
-
Safety evaluation of hemagglutinating virus of Japan-artificial viral envelope liposomes in nonhuman primates
N Tsuboniwa, R Morishita, T Hirano, J Fujimoto, S Furukawa, M Kikumori, A Okuyama, Y Kaneda
HUMAN GENE THERAPY Vol. 12 No. 5 p. 469-487 2001年3月 研究論文(学術雑誌)
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Downregulation of nuclear factor kappa B expression in primate cardiac allograft arteries after E2F decoy transfection
M Kawauchi, J Suzuki, Y Wada, R Morishita, Y Kaneda, M Isobe, J Amano, S Takamoto
TRANSPLANTATION PROCEEDINGS Vol. 33 No. 1-2 p. 451-451 2001年2月 研究論文(学術雑誌)
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Therapeutic angiogenesis induced by human hepatocyte growth factor gene in rat and rabbit hindlimb ischemia models: preclinical study for treatment of peripheral arterial disease.
Taniyama Y, Morishita R, Aoki M, Nakagami H, Yamamoto K, Yamazaki K, Matsumoto K, Nakamura T, Kaneda Y, Ogihara T, Gene therapy
Gene Ther. Vol. 8 No. 3 p. 181-189 2001年2月
-
Mitogenic and antiapoptotic actions of hepatocyte growth factor through ERK, STAT3, and AKT in endothelial cells.
Nakagami H, Morishita R, Yamamoto K, Taniyama Y, Aoki M, Matsumoto K, Nakamura T, Kaneda Y, Horiuchi M, Ogihara T, Hypertension, Dallas, Te
Vol. 37 No. 2 Pt 2 p. 581-586 2001年2月
-
A novel strategy of decoy transfection against nuclear factor-kappaB in myocardial preservation.
Sakaguchi T, Sawa Y, Fukushima N, Nishimura M, Ichikawa H, Kaneda Y, Matsuda H
The Annals of thoracic surgery Vol. 71 No. 2 p. 624-9; discussion 629 2001年2月
-
Reconstitution of chromatin in vitro.
K. Ura, Y. Kaneda
Methods in molecular biology (Clifton, N.J.) Vol. 181 p. 309-325 2001年 研究論文(学術雑誌)
-
DMA vaccines for cancer treatment
Yasufumi Kaneda, Dave S.B. Hoon
IDrugs Vol. 4 No. 3 p. 301-311 2001年 研究論文(学術雑誌)
-
Dominant negative c-Jun gene transfer inhibits vascular smooth muscle cell proliferation and neointimal hyperplasia in rats
H. Yasumoto, S. Kim, Y. Zhan, H. Miyazaki, M. Hoshiga, Y. Kaneda, R. Morishita, H. Iwao
Gene Therapy Vol. 8 No. 22 p. 1682-1689 2001年 研究論文(学術雑誌)
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Gene Therapy: A Battle Against Biological Barriers
Yasufumi Kaneda
Current Molecular Medicine Vol. 1 No. 4 p. 493-499 2001年 研究論文(学術雑誌)
出版者・発行元:Bentham Science Publishers B.V.
-
Improvements in gene therapy technologies
Y. Kaneda
Molecular Urology Vol. 5 No. 2 p. 85-89 2001年 研究論文(学術雑誌)
出版者・発行元:Mary Ann Liebert Inc.
-
Preclinical and therapeutic utility of HVJ liposomes as a gene transfer vector for hepatocellular carcinoma using herpes simplex virus thymidine kinase
Hirofumi Hasegawa, Mitsuo Shimada, Yoshikazu Yonemitsu, Tohru Utsunomiya, Tomonobu Gion, Yasufumi Kaneda, Keizo Sugimachi
Cancer Gene Therapy Vol. 8 No. 4 p. 252-258 2001年 研究論文(学術雑誌)
-
Efficient transfer of intact oligonucleotides into the nucleus of ligament scar fibroblasts by HVJ-cationic liposomes is correlated with effective antisense gene inhibition
Norimasa Nakamura, David A. Hart, Cyril B. Frank, Linda L. Marchuk, Nigel G. Shrive, Naruhisa Ota, Kazunari Taira, Hideki Yoshikawa, Yasufumi Kaneda
Journal of Biochemistry Vol. 129 No. 5 p. 755-759 2001年 研究論文(学術雑誌)
-
An essential role of the antioxidant gene bcl-2 in myocardial adaptation to ischemia: An insight with antisense bcl-2 therapy
R. Hattori, T. Estrada Hernandez, L. Zhu, N. Maulik, H. Otani, Y. Kaneda, D. K. Das
Antioxidants and Redox Signaling Vol. 3 No. 3 p. 403-413 2001年 研究論文(学術雑誌)
出版者・発行元:Mary Ann Liebert Inc.
-
Gene therapy of ischemic-damaged kidney in the rat using hepatocyte growth factor gene
M. Kitamura, N. Tsuboniwa, H. Azuma, J. D. Wang, K. Matsumiya, K. Matsumoto, Y. Kaneda, S. Takahara, A. Okuyama
Transplantation Proceedings Vol. 33 No. 5 p. 2865-2867 2001年 研究論文(学術雑誌)
-
Cells derived from tuberous sclerosis show a prolonged S phase of the cell cycle and increased apoptosis
M. Wataya-Kaneda, Yasufumi Kaneda, Okio Hino, Hiroyuki Adachi, Youko Hirayama, Kuniaki Seyama, Teruhiko Satou, Kunihiko Yoshikawa
Archives of Dermatological Research Vol. 293 No. 9 p. 460-469 2001年 研究論文(学術雑誌)
-
HVJ-liposome-mediated transfection of HSVtk gene driven by AFP promoter inhibits hepatic tumor growth of hepatocellular carcinoma in SCID mice
T Hirano, S Kaneko, Y Kaneda, Saito, I, T Tamaoki, J Furuyama, T Tamaoki, K Kobayashi, T Ueki, J Fujimoto
GENE THERAPY Vol. 8 No. 1 p. 80-83 2001年1月 研究論文(学術雑誌)
-
Decoy oligodeoxynucleotides as novel cardiovascular drugs for cardiovascular disease
R Morishita, M Aoki, Y Kaneda
ATHEROSCLEROSIS VI Vol. 947 p. 294-302 2001年 研究論文(学術雑誌)
-
Inhibition of TNF-a, induced cytokine and adhesion molecule
N Tomita, R Morishita, S Tomita, Y Kaneda, J Higaki, T Ogihara, M Horiuchi
EXPERIMENTAL NEPHROLOGY Vol. 9 No. 3 p. 181-190 2001年 研究論文(学術雑誌)
-
Gene transfer of dominant-negative mutants of extracellular signal-regulated kinase and c-Jun NH2-terminal kinase prevents neointimal formation in balloon-injured rat artery.
泉 康雄
Circ Res Vol. 88 p. 1120-1126 2001年
-
Gene therapy for attenuating cardiac allograft arteriopathy using ex vivo E2F decoy transfection by HVJ-AVE-liposome method in mice and nonhuman primates
M Kawauchi, J Suzuki, R Morishita, Y Wada, A Izawa, N Tomita, J Amano, Y Kaneda, T Ogihara, S Takamoto, M Isobe
CIRCULATION RESEARCH Vol. 87 No. 11 p. 1063-1068 2000年11月 研究論文(学術雑誌)
-
Decoy against nuclear factor-kappa B attenuates myocardial cell infiltration and arterial neointimal formation in murine cardiac allografts
J Suzuki, R Morishita, J Amano, Y Kaneda, M Isobe
GENE THERAPY Vol. 7 No. 21 p. 1847-1852 2000年11月 研究論文(学術雑誌)
-
Gene transfer of the serine elastase inhibitor elafin protects against vein graft degeneration
SB O'Blenes, SHE Zaidi, AYL Cheah, B McIntyre, Y Kaneda, M Rabinovitch
CIRCULATION Vol. 102 No. 19 p. 289-295 2000年11月 研究論文(学術雑誌)
-
Sp1 decoy transfected to carcinoma cells suppresses the expression of vascular endothelial growth factor, transforming growth factor beta(1), and tissue factor and also cell growth and invasion activities
H Ishibashi, K Nakagawa, M Onimaru, EJ Castellanous, Y Kaneda, Y Nakashima, K Shirasuna, K Sueishi
CANCER RESEARCH Vol. 60 No. 22 p. 6531-6536 2000年11月 研究論文(学術雑誌)
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Anti-monocyte chemoattractant protein-1 gene therapy inhibits vascular remodeling in rats: blockade of MCP-1 activity after intramuscular transfer of a mutant gene inhibits vascular remodeling induced by chronic blockade of NO synthesis
K Egashira, M Koyanagi, S Kitamoto, WH Ni, C Kataoka, R Morishita, Y Kaneda, C Akiyama, KI Nishida, K Sueishi, A Takeshita
FASEB JOURNAL Vol. 14 No. 13 p. 1974-1978 2000年10月 研究論文(学術雑誌)
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In vivo transfer of human hepatocyte growth factor gene accelerates re-endothelialization and inhibits neointimal formation after balloon injury in rat model
K Hayashi, S Nakamura, R Morishita, A Moriguchi, M Aoki, K Matsumoto, T Nakamura, Y Kaneda, N Sakai, T Ogihara
GENE THERAPY Vol. 7 No. 19 p. 1664-1671 2000年10月 研究論文(学術雑誌)
-
Gene transfer of human prostacyclin synthase ameliorates monocrotaline-induced pulmonary hypertension in rats
N Nagaya, C Yokoyama, S Kyotani, M Shimonishi, R Morishita, M Uematsu, T Nishikimi, N Nakanishi, T Ogihara, M Yamagishi, K Miyatake, Y Kaneda, T Tanabe
CIRCULATION Vol. 102 No. 16 p. 2005-2010 2000年10月 研究論文(学術雑誌)
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Complexity of determining cause and effect in vivo after antisense gene therapy
DA Hart, N Nakamura, L Marchuk, H Hiraoka, R Boorman, Y Kaneda, NG Shrive, CB Frank
CLINICAL ORTHOPAEDICS AND RELATED RESEARCH No. 379 p. S242-S251 2000年10月 研究論文(学術雑誌)
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遺伝子治療の現状と未来
豊岡 照彦, 金田 安史, 青木 元邦, 森下 竜一, 谷山 義明, 檜垣 実男, 荻原 俊男, 河田 登美枝, 仲澤 幹雄, 阪本 英二, 申 偉秀, ト部 匡司, MONAHAN John, 小澤 敬也, 藤原 俊義, 片岡 正文, 中村 篤, 田中 紀章, 崎山 幸雄
日本薬理学雑誌 Vol. 116 No. 3 p. 158-162 2000年9月1日
出版者・発行元:公益社団法人 日本薬理学会
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HVJ-リポソームを用いた脳毛細血管内皮細胞における遺伝子の導入及び発現
蒋 晨, 松尾 浩民, 小薮 紀子, 大谷 壽一, 藤本 英典, 米満 吉和, 居石 克夫, 金田 安史, 内藤 幹彦, 鶴尾 隆
薬物動態 Vol. 15 No. Suppl. p. S286-S286 2000年9月
出版者・発行元:(一社)日本薬物動態学会
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Catheter-delivered in vivo gene transfer into rat myocardium using the fusigenic liposomal mediated method
K Shinmura, R Morishita, M Aoki, J Higaki, T Ogihara, Y Kaneda, M Tani
JAPANESE HEART JOURNAL Vol. 41 No. 5 p. 633-647 2000年9月 研究論文(学術雑誌)
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Ribozyme oligonucleotides against transforming growth factor-beta inhibited neointimal formation after vascular injury in rat model - Potential application of ribozyme strategy to treat cardiovascular disease
K Yamamoto, R Morishita, N Tomita, T Shimozato, H Nakagami, A Kikuchi, M Aoki, J Higaki, Y Kaneda, T Ogihara
CIRCULATION Vol. 102 No. 11 p. 1308-1314 2000年9月 研究論文(学術雑誌)
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Increased activity of nuclear factor-kappa B participates in cardiovascular remodeling induced by chronic inhibition of nitric oxide synthesis in rats
S Kitamoto, K Egashira, C Kataoka, M Koyanagi, M Katoh, H Shimokawa, R Morishita, Y Kaneda, K Sueishi, A Takeshita
CIRCULATION Vol. 102 No. 7 p. 806-812 2000年8月 研究論文(学術雑誌)
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Ecto-5 '-nucleotidase plays a role in the cardioprotective effects of heat shock protein 72 in ischemia-reperfusion injury in rat hearts
T Sakaguchi, Y Sawa, M Kitakaze, K Suzuki, M Nishimura, Y Kaneda, H Matsuda
CARDIOVASCULAR RESEARCH Vol. 47 No. 1 p. 74-80 2000年7月 研究論文(学術雑誌)
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Systemic administration of HVJ viral coat-liposome complex containing human insulin vector decreases glucose level in diabetic mouse: A model of gene therapy
R Morishita, GH Gibbons, Y Kaneda, T Ogihara, VJ Dzau
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS Vol. 273 No. 2 p. 666-674 2000年7月 研究論文(学術雑誌)
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Transcription factor decoy for NF kappa B inhibits cytokine and adhesion molecule expressions in synovial cells derived from rheumatoid arthritis
T Tomita, H Takano, H Tomita, R Morishita, M Kaneko, K Shi, K Takahi, T Nakase, Y Kaneda, H Yoshikawa, T Ochi
RHEUMATOLOGY Vol. 39 No. 7 p. 749-757 2000年7月 研究論文(学術雑誌)
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Introduction of the interleukin-10 gene into mice inhibited bleomycin- induced lung injury in vivo
Toru Arai, Kin'ya Abe, Hiroto Matsuoka, Mitsuhiro Yoshida, Masahide Mori, Sho Goya, Hiroshi Kida, Kazumi Nishino, Tadashi Osaki, Isao Tachibana, Yasufumi Kaneda, Seiji Hayashi
American Journal of Physiology - Lung Cellular and Molecular Physiology Vol. 278 No. 5 p. L914-L922 2000年5月 研究論文(学術雑誌)
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Gene therapy as a potential treatment for restenosis and myocardial infarction
N Tomita, R Morishita, Y Kaneda, J Higaki, T Ogihara
DRUG NEWS & PERSPECTIVES Vol. 13 No. 4 p. 206-212 2000年5月 研究論文(学術雑誌)
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Hypoxia-induced endothelial apoptosis through nuclear factor-kappa B (NF-kappa B)-mediated bcl-2 suppression - In vivo evidence of the importance of NF-kappa B in endothelial cell regulation
H Matsushita, R Morishita, T Nata, M Aoki, H Nakagami, Y Taniyama, K Yamamoto, J Higaki, K Yasufumi, T Ogihara
CIRCULATION RESEARCH Vol. 86 No. 9 p. 974-981 2000年5月 研究論文(学術雑誌)
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Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage
Takeshi Nishikawa, Diane Edelstein, Xue Liang Du, Sho-Ichi Yamagishi, Takeshi Matsumura, Yasufumi Kaneda, Mark A. Yorek, David Beebe, Peter J. Oates, Hans-Peter Hammes, Ida Glardino, Michael Brownlee
Nature Vol. 404 No. 6779 p. 787-790 2000年4月13日 研究論文(学術雑誌)
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Antisense oligodeoxynucleotide inhibition of vascular angiotensin-converting enzyme expression attenuates neointimal formation - Evidence for tissue angiotensin-converting enzyme function
R Morishita, GH Gibbons, N Tomita, LN Zhang, Y Kaneda, T Ogihara, VJ Dzau
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY Vol. 20 No. 4 p. 915-922 2000年4月 研究論文(学術雑誌)
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Transfection of antisense p53 tumor suppressor gene oligodeoxynucleotides into rat carotid artery results in abnormal growth of vascular smooth muscle cells
H Matsushita, R Morishita, M Aoki, N Tomita, Y Taniyama, H Nakagami, T Shimozato, J Higaki, Y Kaneda, T Ogihara
CIRCULATION Vol. 101 No. 12 p. 1447-1452 2000年3月 研究論文(学術雑誌)
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Antisense Bcl-x oligonucleotide induces apoptosis and prevents arterial neointimal formation in murine cardiac allografts
J Suzuki, M Isobe, R Morishita, T Niskikawa, J Amano, Y Kaneda
CARDIOVASCULAR RESEARCH Vol. 45 No. 3 p. 783-787 2000年2月 研究論文(学術雑誌)
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Enhancement of transgene expression by cotransfection of oriP plasmid with EBNA-1 expression vector
Y Kaneda, Y Saeki, M Nakabayashi, WZ Zhou, MW Kaneda, R Morishita
HUMAN GENE THERAPY Vol. 11 No. 3 p. 471-479 2000年2月 研究論文(学術雑誌)
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Efficacy of hepatocyte-based bioartificial liver on hepatic failure in pigs and several attempts towards clinical application
H Fujioka, Y Kamohara, Y Kawashita, S Eguchi, Y Kawazoe, N Sugiyama, A Tamura, H Moriuchi, J Furui, A Ohtsuru, S Yamashita, Y Kaneda, T Kanematsu
TISSUE ENGINEERING FOR THERAPEUTIC USE 4 Vol. 1198 p. 167-176 2000年 研究論文(国際会議プロシーディングス)
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Phorbol ester-potentiated liposomal transfection to monocytic PLB-985 cells
Li Jun Hao, Dan Yang, Yoshito Fujii, Akira Yamauchi, Norio Suzuki, Hiroshi Kikuchi, Yasufumi Kaneda, Michio Nakamura
Journal of Biochemistry Vol. 128 No. 6 p. 989-998 2000年 研究論文(学術雑誌)
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Inhibition of experimental choroidal neovascularization by overexpression of tissue inhibitor of metalloproteinases-3 in retinal pigment epithelium cells
Tadashi Takahashi, Takao Nakamura, Atsushi Hayashi, Motohiro Kamei, Mari Nakabayashi, Annabelle A. Okada, Naruya Tomita, Yasufumi Kaneda, Yasuo Tano
American Journal of Ophthalmology Vol. 130 No. 6 p. 774-781 2000年 研究論文(学術雑誌)
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Inhibition of growth of melanoma cells by CD95 (Fas/APO-1) gene transfer in vivo
Yoshinori Aragane, Akira Maeda, Chang-Yi Cui, Tadashi Tezuka, Yasufumi Kaneda, Thomas Schwarz
Journal of Investigative Dermatology Vol. 115 No. 6 p. 1008-1014 2000年 研究論文(学術雑誌)
出版者・発行元:Blackwell Publishing Inc.
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Decorin antisense gene therapy improves functional healing of early rabbit ligament scar with enhanced collagen fibrillogenesis in vivo
Norimasa Nakamura, David A. Hart, Richard S. Boorman, Yasufumi Kaneda, Nigel G. Shrive, Linda L. Marchuk, Konsei Shino, Takahiro Ochi, Cyril B. Frank
Journal of Orthopaedic Research Vol. 18 No. 4 p. 517-523 2000年 研究論文(学術雑誌)
出版者・発行元:J Bone Jt Surgery Inc.
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Oligonucleotide-based Gene Therapy for Cardiovascular Disease: Are Oligonucleotide Therapeutics Novel Cardiovascular Drugs ?
Ryuichi Morishita, Motokuni Aoki, Yasufumi Kaneda
Current Drug Targets Vol. 1 No. 1 p. 15-23 2000年 研究論文(学術雑誌)
出版者・発行元:Bentham Science Publishers B.V.
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Suppression of copulatory behavior by intracerebroventricular infusion of antisense oligodeoxynucleotide of granulin in neonatal male rats
Masatoshi Suzuki, Makoto Bannai, Mie Matsumuro, Yasufumi Furuhata, Ryota Ikemura, Erina Kuranaga, Yasufumi Kaneda, Masugi Nishihara, Michio Takahashi
Physiology and Behavior Vol. 68 No. 5 p. 707-713 2000年 研究論文(学術雑誌)
出版者・発行元:Elsevier Inc.
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In vivo gene transfer into choroidal neovascularization by the HVJ liposome method
Tsuyoshi Otsuji, Nahoko Ogata, Kanji Takahashi, Masashi Matsushima, Masanobu Uyama, Yasufumi Kaneda
Graefe's Archive for Clinical and Experimental Ophthalmology Vol. 238 No. 2 p. 191-199 2000年 研究論文(学術雑誌)
出版者・発行元:Springer Verlag
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Gene transfer targeting interstitial fibroblasts by the artificial viral envelope-type hemagglutinating virus of Japan liposome method
Michiko Tsujie, Yoshitaka Isaka, Yutaka Ando, Yoshitaka Akagi, Yasufumi Kaneda, Naohiko Ueda, Enyu Imai, Masatsugu Hori
Kidney International Vol. 57 No. 5 p. 1973-1980 2000年 研究論文(学術雑誌)
出版者・発行元:Blackwell Publishing Inc.
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Changes in pulmonary histology and exfoliated bronchoalveolar cells induced by in vivo introduction of the tumor necrosis factor-α gene
Junko Sakuma-Mochizuki, Mitsuhiro Yoshida, Kin'Ya Abe, Toru Arai, Masahide Mori, Yasufumi Kaneda, Seiji Hayashi
Inflammation Vol. 24 No. 1 p. 11-19 2000年 研究論文(学術雑誌)
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Introduction of plasmid DNA and oligonucleotides into lung epithelial cells by the hemagglutinating virus of Japan (HVJ)-liposome method
Mitsuhiro Yoshida, Seiji Hayashi, Junko Sakuma-Mochizuki, Kin'nya Abe, Toru Arai, Masahide Mori, Sho Goya, Hiroto Matsuoka, Yasufumi Kaneda, Tadamitsu Kishimoto
Somatic Cell and Molecular Genetics Vol. 25 No. 1 p. 49-57 2000年 研究論文(学術雑誌)
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Reduction in myocardial apoptosis associated with overexpression of heat shock protein 70
Ken Suzuki, Yoshiki Sawa, Koji Kagisaki, Satoshi Taketani, Hajime Ichikawa, Yasufumi Kaneda, Hikaru Matsuda
Basic Research in Cardiology Vol. 95 No. 5 p. 397-403 2000年 研究論文(学術雑誌)
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Transforming growth factor-β1 antisense oligodeoxynucleotides block interstitial fibrosis in unilateral ureteral obstruction
Y. Isaka, M. Tsujie, Y. Ando, H. Nakamura, Y. Kaneda, E. Imai, M. Hori
Kidney International Vol. 58 No. 5 p. 1885-1892 2000年 研究論文(学術雑誌)
出版者・発行元:Blackwell Publishing Inc.
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Gene therapy for heart transplantation-associated coronary arteriosclerosis
M Isobe, JI Suzuki, R Morishita, Y Kaneda, J Amano
ATHEROSCLEROSIS V: THE FIFTH SARATOGA CONFERENCE Vol. 902 p. 77-83 2000年 研究論文(学術雑誌)
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Gene therapy for myocardial infarction: A real medicine in the next millenium?
R Morishita, M Aoki, H Nakagami, Y Taniyama, K Yamamoto, H Matsushita, K Matsumoto, J Higaki, Y Kaneda, T Ogihara
HEART FAILURE p. 219-226 2000年 研究論文(国際会議プロシーディングス)
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Efficient introduction of macromolecules and oligonucleotides into brain capillary endothelial cells using HVJ-liposomes
H Matsuo, T Okamura, J Chen, H Takanaga, Y Kaneda, M Naito, T Tsuruo, Y Sawada
JOURNAL OF DRUG TARGETING Vol. 8 No. 4 p. 207-+ 2000年 研究論文(学術雑誌)
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Gene therapy for cardiovascular disease using hepatocyte growth factor
R Morishita, M Aoki, S Nakamura, J Higaki, Y Kaneda, T Ogihara
ATHEROSCLEROSIS V: THE FIFTH SARATOGA CONFERENCE Vol. 902 p. 369-376 2000年 研究論文(学術雑誌)
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Eradication of breast cancer xenografts by hyperthermic suicide gene therapy under the control of the heat shock protein promoter.
Braiden V, Ohtsuru A, Kawashita Y, Miki F, Sawada T, Ito M, Cao Y, Kaneda Y, Koji T, Yamashita S
Hum Gene Ther Vol. 11 No. 18 p. 2453-2463 2000年 研究論文(学術雑誌)
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Amplification of transgene expression in vitro and in vivo using a novel inhibitor of histone deacetylase
山野智基
Molecular Therapy Vol. 1 No. 6 p. 574-580 2000年 研究論文(学術雑誌)
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Suppressed severity of collagen-induced arthritis by in vivo transfection of nuclear factor kappa B decoy oligodeoxynucleotides as a gene therapy
T Tomita, E Takeuchi, N Tomita, R Morishita, M Kaneko, K Yamamoto, T Nakase, H Seki, K Kato, Y Kaneda, T Ochi
ARTHRITIS AND RHEUMATISM Vol. 42 No. 12 p. 2532-2542 1999年12月 研究論文(学術雑誌)
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Transfection of rat kidney with human 15-lipoxygenase suppresses inflammation and preserves function in experimental glomerulonephritis
Karen A. Munger, Angel Montero, Megumu Fukunaga, Susumu Uda, Takafumi Yura, Enyu Imai, Yasufumi Kaneda, José M. Valdivielso, Kamal F. Badr
Proceedings of the National Academy of Sciences of the United States of America Vol. 96 No. 23 p. 13375-13380 1999年11月9日 研究論文(学術雑誌)
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Allogeneic class I major histocompatibility complex gene transfer in murine neuroblastoma in vivo
Hiroyuki Ishida, Yasufumi Kaneda, Shuich Yamane, Tadashi Sawada, Gregory E. Plautz, Takafumi Matsumura
Anticancer Research Vol. 19 No. 6 B p. 5367-5373 1999年11月 研究論文(学術雑誌)
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In vivo gene transfer of an extracellular domain of platelet-derived growth factor beta receptor by the HVJ-liposome method ameliorates bleomycin-induced pulmonary fibrosis
M Yoshida, J Sakuma-Mochizuki, K Abe, T Arai, M Mori, S Goya, H Matsuoka, S Hayashi, Y Kaneda, T Kishimoto
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS Vol. 265 No. 2 p. 503-508 1999年11月 研究論文(学術雑誌)
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Myocardial protection with endogenous overexpression of manganese superoxide dismutase
Ken Suzuki, Yoshiki Sawa, Hajime Ichikawa, Yasufumi Kaneda, Hikaru Matsuda
Annals of Thoracic Surgery Vol. 68 No. 4 p. 1266-1271 1999年10月 研究論文(国際会議プロシーディングス)
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Protective immunization against melanoma by gp100 DNA-HVJ-liposome vaccine
WZ Zhou, Y Kaneda, SKS Huang, R Morishita, DSB Hoon
GENE THERAPY Vol. 6 No. 10 p. 1768-1773 1999年10月 研究論文(学術雑誌)
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Gene transfection of beta 2-adrenergic receptor into the normal rat heart enhances cardiac response to beta-adrenergic agonist
Y Kawahira, Y Sawa, M Nishimura, S Sakakida, H Ueda, Y Kaneda, H Matsuda
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY Vol. 118 No. 3 p. 446-451 1999年9月 研究論文(学術雑誌)
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E2F decoy suppresses E-selectin expression in murine cardiac allograft arteriopathy
J Suzuki, M Isobe, R Morishita, A Izawa, S Yamazaki, Y Okubo, Y Kaneda, M Sekiguchi
TRANSPLANTATION PROCEEDINGS Vol. 31 No. 5 p. 2018-2019 1999年8月 研究論文(学術雑誌)
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Activation of the brain angiotensin system by in vivo human angiotensin-converting enzyme gene transfer in rats
S Nakamura, A Moriguchi, R Morishita, K Yamada, T Nishii, N Tomita, M Ohishi, Y Kaneda, J Higaki, T Ogihara
HYPERTENSION Vol. 34 No. 2 p. 302-308 1999年8月 研究論文(学術雑誌)
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Inhibition of the p53 tumor suppressor gene results in growth of human aortic vascular smooth muscle cells. Potential role of p53 in regulation of vascular smooth muscle cell growth.
Aoki M, Morishita R, Matsushita H, Hayashi S, Nakagami H, Yamamoto K, Moriguchi A, Kaneda Y, Higaki J, Ogihara T, Hypertension, Dallas, Te
Vol. 34 No. 2 p. 192-200 1999年8月 研究論文(学術雑誌)
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Gene transfection of hepatocyte growth factor attenuates reperfusion injury in the heart
H Ueda, Y Sawa, K Matsumoto, S Kitagawa-Sakakida, Y Kawahira, T Nakamura, Y Kaneda, H Matsuda
ANNALS OF THORACIC SURGERY Vol. 67 No. 6 p. 1726-1731 1999年6月 研究論文(学術雑誌)
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Transcription factor decoy to study the molecular mechanism of negative regulation of renin gene expression in the liver in vivo
S Tomita, N Tomita, T Yamada, LN Zhang, Y Kaneda, R Morishita, T Ogihara, VJ Dzau, M Horiuchi
CIRCULATION RESEARCH Vol. 84 No. 9 p. 1059-1066 1999年5月 研究論文(学術雑誌)
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【イオンチャネルと疾患】イオンチャネル病の遺伝子治療 嚢胞性線維症遺伝子治療臨床試験の現状と展望
米満 吉和, 金田 安史, Alton Eric WFW
現代医療 Vol. 31 No. 4 p. 1044-1050 1999年4月
出版者・発行元:(株)現代医療社
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Phosphorothioate oligonucleotides induction into experimental choroidal neovascularization by HVJ-liposome system
N Ogata, T Otsuji, M Matsushima, T Kimoto, R Yamanaka, K Takahashi, M Wada, M Uyama, Y Kaneda
CURRENT EYE RESEARCH Vol. 18 No. 4 p. 261-269 1999年4月 研究論文(学術雑誌)
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Ribosome-associated protein LBP/p40 binds to S21 protein of 40S ribosome: Analysis using a yeast two-hybrid system
Manabu Sato, Yoshinaga Saeki, Kiyoji Tanaka, Yasufumi Kaneda
Biochemical and Biophysical Research Communications Vol. 256 No. 2 p. 385-390 1999年3月16日 研究論文(学術雑誌)
出版者・発行元:Academic Press Inc.
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Prevention of cardiac allograft arteriopathy by antisense cdc2 kinase oligonucleotide
J Suzuki, A Izawa, R Morishita, Y Kaneda, Y Sawa, Y Okubo, T Ogihara, M Sekiguchi, M Isobe
TRANSPLANTATION PROCEEDINGS Vol. 31 No. 1-2 p. 867-868 1999年2月 研究論文(学術雑誌)
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Antisense Cdc2 kinase oligonucleotide inhibits adhesion molecule expression in cardiac allograft arteriopathy
J Suzuki, A Izawa, R Morishita, Y Kaneda, Y Sawa, Y Okubo, T Ogihara, M Sekiguchi, M Isobe
TRANSPLANTATION PROCEEDINGS Vol. 31 No. 1-2 p. 955-956 1999年2月 研究論文(学術雑誌)
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Gene transfer in utero biologically engineers a patent ductus arteriosus in lambs by arresting fibronectin-dependent neointimal formation
CAE Mason, JL Bigras, SB O'Blenes, B Zhou, B McIntyre, N Nakamura, Y Kaneda, M Rabinovitch
NATURE MEDICINE Vol. 5 No. 2 p. 176-182 1999年2月 研究論文(学術雑誌)
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Optimization of the biology of soft tissue repair.
Frank C, Shrive, N, Hiraoka, H, Nakamura, N, Kaneda, Y, Hart, D
J. Sci. Med. Sport Vol. 2 p. 190-210 1999年
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Gene Therapy for Attenuating Chronic Rejection of Cardiac Allografts
Jun-ichi Suzuki, Mitsuaki Isobe, Ryuichi Morishita, Yasufumi Kaneda, Motohiro Kawauchi, Jun Amano
Japanese Journal of Clinical Immunology Vol. 22 No. 6 p. 418-421 1999年 研究論文(学術雑誌)
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Gene transfer to the rat biliary tract with the HVJ-cationic liposome method
Tetsuya Uehara, Kazuo Honda, Etsuro Hatano, Ryuta Terao, Yuji Iimuro, Naritaka Yamamoto, Masayuki Yamamoto, Yasufumi Kaneda, Yoshio Yamaoka
Journal of Hepatology Vol. 30 No. 5 p. 836-842 1999年 研究論文(学術雑誌)
出版者・発行元:Blackwell Munksgaard
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Direct in vivo gene transfer to healing rat patellar ligament by intra-arterial delivery of haemagglutinating virus of Japan liposomes
I. Özkan, K. Shino, N. Nakamura, T. Natsu-ume, N. Matsumoto, S. Horibe, T. Tomita, Y. Kaneda, T. Ochi
European Journal of Clinical Investigation Vol. 29 No. 1 p. 63-67 1999年 研究論文(学術雑誌)
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Gene therapy by transforming growth factor-β receptor-IgG Fc chimera suppressed extracellular matrix accumulation in experimental glomerulonephritis
Yoshitaka Isaka, Yoshitaka Akagi, Yutaka Ando, Michiko Tsujie, Tetsuo Sudo, Noriko Ohno, Wayne A. Border, Nancy A. Noble, Yasufumi Kaneda, Masatsugu Hori, Enyu Imai
Kidney International Vol. 55 No. 2 p. 465-475 1999年 研究論文(学術雑誌)
出版者・発行元:Blackwell Publishing Inc.
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Development of a novel fusogenic viral liposome system (HVJ-liposomes) and its applications to the treatment of acquired diseases
Yasufumi Kaneda
Molecular Membrane Biology Vol. 16 No. 1 p. 119-122 1999年 研究論文(国際会議プロシーディングス)
出版者・発行元:Taylor and Francis Ltd
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Gene transfer of human prostacyclin synthase prevents neointimal formation after carotid balloon injury in rats
T. Todaka, T. Todaka, C. Yokoyama, Hiroji Yanamoto, Hiroji Yanamoto, Hiroji Yanamoto, N. Hashimoto, I. Nagata, T. Tsukahara, S. Hara, T. Hatae, R. Morishita, M. Aoki, T. Ogihara, Y. Kaneda, T. Tanabe, T. Tanabe
Stroke Vol. 30 p. 419-426 1999年1月1日
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LBP-p40 binds DNA tightly through associations with histones H2A, H2B, and H4
Katsunari Kinoshita, Yoshinao Kaneda, Manabu Sato, Yoshinaga Saeki, Mari Wataya-Kaneda, Alexander Hoffmann, Yasufumi Kaneda
Biochemical and Biophysical Research Communications Vol. 253 No. 2 p. 277-282 1998年12月18日 研究論文(学術雑誌)
出版者・発行元:Academic Press Inc.
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Prolonged survival of rat liver allografts transfected with Fas ligand- expressing plasmid
Xiao-Kang Li, Torayuki Okuyama, Akihiko Tamura, Shin Enosawa, Yasufumi Kaneda, Shiro Takahara, Naoko Funashima, Masao Yamada, Hiroshi Amemiya, Seiichi Suzuki
Transplantation Vol. 66 No. 11 p. 1416-1423 1998年12月15日 研究論文(学術雑誌)
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Efficient transfer of oligonucleotides and plasmid DNA into the whole heart through the coronary artery
Y Sawa, Y Kaneda, HZ Bai, K Suzuki, J Fujimoto, R Morishita, H Matsuda
GENE THERAPY Vol. 5 No. 11 p. 1472-1480 1998年11月 研究論文(学術雑誌)
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In vivo transfer of a beta(2)-adrenergic receptor gene into the pressure-overloaded rat heart enhances cardiac response to beta-adrenergic agonist
Y Kawahira, Y Sawa, M Nishimura, S Sakakida, H Ueda, Y Kaneda, H Matsuda
CIRCULATION Vol. 98 No. 19 p. II262-II267 1998年11月 研究論文(学術雑誌)
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Novel therapeutic strategy for atherosclerosis - Ribozyme oligonucleotides against apolipoprotein(a) selectively inhibit apolipoprotein(a) but not plasminogen gene expression
R Morishita, S Yamada, K Yamamoto, N Tomita, Kida, I, Sakurabayashi, I, A Kikuchi, Y Kaneda, R Lawn, J Higaki, T Ogihara
CIRCULATION Vol. 98 No. 18 p. 1898-1904 1998年11月 研究論文(学術雑誌)
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Gene transfer to vein graft wall by HVJ-liposome method: Time course and localization of gene expression
HZ Bai, Y Sawa, WD Zhang, T Yamakawa, R Morishita, Y Kaneda, H Matsuda
ANNALS OF THORACIC SURGERY Vol. 66 No. 3 p. 814-819 1998年9月 研究論文(学術雑誌)
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Stimulatory effect of lipoprotein (a) on proliferation of human mesangial cells: Role of lipoprotein (a) in renal disease
R Morishita, K Yamamoto, S Yamada, H Matsushita, N Tomita, Sakurabayashi, I, Y Kaneda, A Moriguchi, J Higaki, T Ogihara
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS Vol. 249 No. 2 p. 313-320 1998年8月 研究論文(学術雑誌)
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Conditioned medium from HepG2 cells transfected with human apolipoprotein(a) gene stimulates growth of human vascular smooth muscle cells - Effects of overexpression of human apolipoprotein(a) gene
R Morishita, S Yamada, J Higaki, N Tomita, Kida, I, M Aoki, A Moriguchi, S Hayashi, Sakurabayashi, I, Y Kaneda, T Ogihara
HYPERTENSION Vol. 32 No. 2 p. 215-222 1998年8月 研究論文(学術雑誌)
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Functional analysis of cis-element and binding protein as regulators of angiotensinogen generation in SHR.
T Nishii, A Moriguchi, R Morishita, N Tomita, S Nakamura, Y Kaneda, J Higaki, T Ogihara
JAPANESE HEART JOURNAL Vol. 39 No. 4 p. 554-554 1998年7月 研究論文(学術雑誌)
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HVJ-リポソームによる遺伝子導入
金田 安史
化学と生物 Vol. 36 No. 6 p. 376-384 1998年6月25日
出版者・発行元:Japan Society for Bioscience, Biotechnology, and Agrochemistry
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Overexpressed heat shock protein 70 attenuates hypoxic injury in coronary endothelial cells
K Suzuki, Y Sawa, Y Kaneda, H Ichikawa, R Shirakura, H Matsuda
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY Vol. 30 No. 6 p. 1129-1136 1998年6月 研究論文(学術雑誌)
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HVJ (Sendai virus) liposome-mediated gene transfer: current status and future perspectives (Review)
Y Yonemitsu, EWFW Alton, K Komori, T Yoshizumi, K Sugimachi, Y Kaneda
INTERNATIONAL JOURNAL OF ONCOLOGY Vol. 12 No. 6 p. 1277-1285 1998年6月 研究論文(学術雑誌)
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Downregulation of endothelin expression in allograft coronary arteries after gene therapy targeting Cdk2 kinase
M Isobe, J Suzuki, R Morishita, Y Kaneda, Y Sawa, H Matsuda, T Ogihara, S Horie, Y Okubo, J Amano
TRANSPLANTATION PROCEEDINGS Vol. 30 No. 4 p. 1007-1008 1998年6月 研究論文(学術雑誌)
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Heterogeneous induction of apoptosis in colon cancer cells by wild-type p53 gene transfection
M Namoto, Y Yonemitsu, K Nakagawa, S Hashimoto, Y Kaneda, H Nawata, K Sueishi
INTERNATIONAL JOURNAL OF ONCOLOGY Vol. 12 No. 4 p. 777-784 1998年4月 研究論文(学術雑誌)
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Persistent gene expression in rat liver in vivo by repetitive transfections using HVJ-liposome
T Hirano, J Fujimoto, T Ueki, H Yamamoto, T Iwasaki, R Morisita, Y Sawa, Y Kaneda, H Takahashi, E Okamoto
GENE THERAPY Vol. 5 No. 4 p. 459-464 1998年4月 研究論文(学術雑誌)
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Introduction of DNA into the rat and primate trabecular meshwork by fusogenic liposomes
Masanori Hangai, Hidenobu Tanihara, Yoshihito Honda, Yasufumi Kaneda
Investigative Ophthalmology and Visual Science Vol. 39 No. 3 p. 509-516 1998年3月 研究論文(学術雑誌)
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Transfer of wild-type p53 gene effectively inhibits vascular smooth muscle cell proliferation in vitro and in vivo
Y Yonemitsu, Y Kaneda, S Tanaka, Y Nakashima, K Komori, K Sugimachi, K Sueishi
CIRCULATION RESEARCH Vol. 82 No. 2 p. 147-156 1998年2月 研究論文(学術雑誌)
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Role of AP-1 complex in angiotensin II-mediated transforming growth factor-beta expression and growth of smooth muscle cells: Using decoy approach against AP-1 binding site
R Morishita, GH Gibbons, M Horiuchi, Y Kaneda, T Ogihara, VJ Dzau
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS Vol. 243 No. 2 p. 361-367 1998年2月 研究論文(学術雑誌)
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Antisense Cdk2 kinase oligodeoxynucleotide inhibits ICAM-1 expression in murine cardiac allograft arteriopathy
J Suzuki, M Isobe, R Morishita, M Aoki, S Yamazaki, Y Kaneda, Y Sawa, H Matsuda, T Ogihara, S Horie, Y Okubo, M Sekiguchi
TRANSPLANTATION PROCEEDINGS Vol. 30 No. 1 p. 89-90 1998年2月 研究論文(学術雑誌)
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In vivo delivery of phosphorothioate oligonucleotides into murine retina
Masanori Hangai, Hidenobu Tanihara, Yoshihito Honda, Yasufumi Kaneda
Archives of Ophthalmology Vol. 116 No. 3 p. 342-348 1998年 研究論文(学術雑誌)
出版者・発行元:American Medical Association
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Prolonged survival of recipient rats with Fas-ligand-transfected liver allografts by using HVJ-liposome
X. K. Li, T. Okuyama, A. Tamura, M. Fujino, N. Funeshima, Y. Kaneda, Y. Kita, S. Enosawa, H. Amemiya, S. Suzuki
Transplantation Proceedings Vol. 30 No. 4 1998年 研究論文(国際会議プロシーディングス)
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Growth inhibition of cultured human Tenon's fibroblastic cells by targeting the E2F transcription factor
Masayuki Akimoto, Masanori Hangai, Kazushiro Okazaki, Junichi Kogishi, Yoshihito Honda, Yasufumi Kaneda
Experimental Eye Research Vol. 67 No. 4 p. 395-401 1998年 研究論文(学術雑誌)
出版者・発行元:Academic Press
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The HVJ liposome method
Yoshitaka Isaka, Yoshitaka Akagi, Yasufumi Kaneda, Enyu Imai
Experimental Nephrology Vol. 6 No. 2 p. 144-147 1998年 研究論文(国際会議プロシーディングス)
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The induction of apoptosis in HeLa cells by the loss of LBP-p40
Yasufumi Kaneda, Yoshinao Kaneda, Katsunari Kinoshita, Manabu Sato, Yoshinaga Saeki, Ryo Yamada, Mari Wataya-Kaneda, Kiyoji Tanaka
Cell Death and Differentiation Vol. 5 No. 1 p. 20-28 1998年 研究論文(学術雑誌)
出版者・発行元:Nature Publishing Group
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A comparison of in vivo gene delivery methods for antisense therapy in ligament healing
N. Nakamura, S. A. Timmermann, D. A. Hart, Y. Kaneda, N. G. Shrive, K. Shino, T. Ochi, C. B. Frank
Gene Therapy Vol. 5 No. 11 p. 1455-1461 1998年 研究論文(学術雑誌)
出版者・発行元:Nature Publishing Group
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Sustained transgene expression in vitro and in vivo using an epstein-barr virus replicon vector system combined with HVJ liposomes
Y. Saeki, M. Wataya-Kaneda, K. Tanaka, Y. Kaneda
Gene Therapy Vol. 5 No. 8 p. 1031-1037 1998年 研究論文(学術雑誌)
出版者・発行元:Nature Publishing Group
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Early biological effect of in vivo gene transfer of platelet-derived growth factor (PDGF)-B into healing patellar ligament
N. Nakamura, K. Shino, T. Natsuume, S. Horibe, N. Matsumoto, Y. Kaneda, T. Ochi
Gene Therapy Vol. 5 No. 9 p. 1165-1170 1998年 研究論文(学術雑誌)
出版者・発行元:Nature Publishing Group
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Antitumor activity of tumor necrosis factor alpha conjugated with divinyl ether and maleic anhydride copolymer on solid tumors in mice
Y Kaneda, Y Yamamoto, H Kamada, S Tsunoda, Y Tsutsumi, T Hirano, T Mayumi
CANCER RESEARCH Vol. 58 No. 2 p. 290-295 1998年1月 研究論文(学術雑誌)
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Inhibition of growth of human vascular smooth muscle cells by overexpression of p21 gene through induction of apoptosis
H Matsushita, R Morishita, Kida, I, M Aoki, S Hayashi, N Tomita, K Yamamoto, A Moriguchi, A Noda, Y Kaneda, J Higaki, T Ogihara
HYPERTENSION Vol. 31 No. 1 p. 493-498 1998年1月 研究論文(学術雑誌)
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Hemagglutinating virus of Japan-liposome-mediated gene transfer of endothelial cell nitric oxide synthase inhibits intimal hyperplasia of canine vein grafts under conditions of poor runoff
T Matsumoto, K Komori, Y Yonemitsu, R Morishita, K Sueishi, Y Kaneda, K Sugimachi
JOURNAL OF VASCULAR SURGERY Vol. 27 No. 1 p. 135-144 1998年1月 研究論文(学術雑誌)
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Ribozyme-based gene cleavage approach to chronic arthritis associated with human T cell leukemia virus type I
Isao Kitajima, Naohiro Hanyu, Koichi Kawahara, Yasuko Soejima, Toshikazu Kubo, Ryo Yamada, Yasufumi Kaneda, Ikuro Maruyama
Arthritis and Rheumatism Vol. 40 No. 12 p. 2118-2127 1997年12月 研究論文(学術雑誌)
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Development and characterization of cationic liposomes conjugated with HVJ (Sendai virus): Reciprocal effect of cationic lipid for in vitro and in vivo gene transfer
Yoshinaga Saeki, Norinao Matsumoto, Yoshiro Nakano, Masato Mori, Koji Awai, Yasufumi Kaneda
Human Gene Therapy Vol. 8 No. 17 p. 2133-2141 1997年11月20日 研究論文(学術雑誌)
出版者・発行元:Mary Ann Liebert Inc.
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A novel strategy for myocardial protection using in vivo transfection of cis element 'decoy' against NFkB binding site - Evidence for a role of NFkB in ischemia-reperfusion injury
Y Sawa, R Morishita, K Suzuki, K Kagisaki, Y Kaneda, R Maeda, K Kadoba, H Matsuda
CIRCULATION Vol. 96 No. 9 p. 280-284 1997年11月 研究論文(学術雑誌)
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【遺伝子診断】染色体構造蛋白の免疫染色法
金田 眞理, 金田 安史
臨床検査 Vol. 41 No. 10 p. 1173-1178 1997年10月
出版者・発行元:(株)医学書院
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HVJ (Sendai virus)-cationic liposomes: A novel and potentially effective liposome-mediated technique for gene transfer to the airway epithelium
Y Yonemitsu, Y Kaneda, A Muraishi, T Yoshizumi, K Sugimachi, K Sueishi
GENE THERAPY Vol. 4 No. 7 p. 631-638 1997年7月 研究論文(学術雑誌)
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In vivo direct gene transfer into articular cartilage by intraarticular injection mediated by HVJ (Sendai virus) and liposomes
T Tomita, H Hashimoto, N Tomita, R Morishita, SB Lee, K Hayashida, N Nakamura, K Yonenobu, Y Kaneda, T Ochi
ARTHRITIS AND RHEUMATISM Vol. 40 No. 5 p. 901-906 1997年5月 研究論文(学術雑誌)
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In vivo gene transfection with heat shock protein 70 enhances myocardial tolerance to ischemia-reperfusion injury in rat
K Suzuki, Y Sawa, Y Kaneda, H Ichikawa, R Shirakura, H Matsuda
JOURNAL OF CLINICAL INVESTIGATION Vol. 99 No. 7 p. 1645-1650 1997年4月 研究論文(学術雑誌)
-
Efficient in vivo gene transfer into the heart in the rat myocardial infarction model using the HVJ (hemagglutinating virus of Japan) - Liposome method
M Aoki, R Morishita, A Muraishi, A Moriguchi, T Sugimoto, K Maeda, VJ Dzau, Y Kaneda, J Higaki, T Ogihara
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY Vol. 29 No. 3 p. 949-959 1997年3月 研究論文(学術雑誌)
-
In vivo transfer efficiency of antisense oligonucleotides into the myocardium using HVJ-liposome method
M Aoki, R Morishita, J Higaki, A Moriguchi, Kida, I, S Hayashi, H Matsushita, Y Kaneda, T Ogihara
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS Vol. 231 No. 3 p. 540-545 1997年2月 研究論文(学術雑誌)
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The immediate early gene of human cytomegalovirus stimulates vascular smooth muscle cell proliferation in vitro and in vivo
Y Yonemitsu, Y Kaneda, K Komori, K Hirai, K Sugimachi, K Sueishi
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS Vol. 231 No. 2 p. 447-451 1997年2月 研究論文(学術雑誌)
-
Survival of grafts of genetically modified cardiac myocytes transfected with FITC-labeled oligodeoxynucleotides and the beta-galactosidase gene in the noninfarcted area, but not the myocardial infarcted area
M Aoki, R Morishita, J Higaki, A Moriguchi, S Hayashi, H Matsushita, Kida, I, N Tomita, Y Sawa, Y Kaneda, T Ogihara
GENE THERAPY Vol. 4 No. 2 p. 120-127 1997年2月 研究論文(学術雑誌)
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In vivo gene transfection of human endothelial cell nitric oxide synthase in cardiomyocytes causes apoptosis-like cell death: Identification using Sendai virus-coated liposomes
Hiroyuki Kawaguchi, Wee Soo Shin, Yuepeng Wang, Masao Inukai, Masayoshi Kato, Yoko Matsuo-Okai, Aiji Sakamoto, Yoshio Uehara, Yasufumi Kaneda, Teruhiko Toyo-oka
Circulation Vol. 95 No. 10 p. 2441-2447 1997年 研究論文(学術雑誌)
出版者・発行元:Lippincott Williams and Wilkins
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Efficient gene transfer method into the whole heart through the coronary artery with hemagglutinating virus of Japan liposome
A. S. Weebster, Y. Sawa, K. Kadoba, K. Suzuki, H. Z. Bai, Y. Kaneda, R. Shirakura, H. Matsuda, E. D. Verrier, J. K. Kirklin, F. W. Sellke
Journal of Thoracic and Cardiovascular Surgery Vol. 113 No. 3 p. 510-519 1997年 研究論文(学術雑誌)
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Experimental bronchiolitis obliterans induced by in vivo HVJ-liposome- mediated endothelin-1 gene transfer
Shin-Ichi Takeda, Yoshiki Sawa, Masato Minami, Yasufumi Kaneda, Yoshitaka Fujii, Ryota Shirakura, Masashi Yanagisawa, Hikaru Matsuda
Annals of Thoracic Surgery Vol. 63 No. 6 p. 1562-1567 1997年 研究論文(学術雑誌)
出版者・発行元:Elsevier USA
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Wild-type p53 gene transfer: A novel therapeutic strategy for neointimal hyperplasia after arterial injury
Yoshikazu Yonemitsu, Yasufumi Kaneda, Yasuaki Hata, Yutaka Nakashima, Katsuo Sueishi
Annals of the New York Academy of Sciences Vol. 811 p. 395-400 1997年 研究論文(国際会議プロシーディングス)
出版者・発行元:Blackwell Publishing Inc.
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Its pathophysiological significance in humans as well as in an animal model induced by the gene transfer of vascular endothelial growth factor
K Sueishi, Y Yonemitsu, K Nakagawa, Y Kaneda, M Kumamoto, Y Nakashima
ATHEROSCLEROSIS IV: RECENT ADVANCES IN ATHEROSCLEROSIS RESEARCH Vol. 811 p. 311-324 1997年 研究論文(学術雑誌)
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Prevention of restenosis by gene therapy
Y Kaneda, R Morishita, VJ Dzau
ATHEROSCLEROSIS IV: RECENT ADVANCES IN ATHEROSCLEROSIS RESEARCH Vol. 811 p. 299-310 1997年 研究論文(学術雑誌)
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Analysis of nuclear localization of laminin binding protein precursor p40 (LBP/p40)
Manabu Sato, Katsunari Kinoshita, Yoshinao Kaneda, Yoshinaga Saeki, Akihiro Iwamatsu, Kiyoji Tanaka, Yasufumi Kaneda
Biochemical and Biophysical Research Communications Vol. 229 No. 3 p. 896-901 1996年12月24日 研究論文(学術雑誌)
出版者・発行元:Academic Press Inc.
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In vivo gene transfer into the retina mediated by a novel liposome system
Masanori Hangai, Yasufumi Kaneda, Hidenobu Tanihara, Yoshihito Honda
Investigative Ophthalmology and Visual Science Vol. 37 No. 13 p. 2678-2685 1996年12月 研究論文(学術雑誌)
-
Efficient oligonucleotide delivery using the HVJ-liposome method in the central nervous system
Kazuo Yamada, Atsushi Moriguchi, Ryuichi Morishita, Motokuni Aoki, Yoshio Nakamura, Hiroshi Mikami, Takeo Oshima, Mitsuyoshi Ninomiya, Yasufumi Kaneda, Jitsuo Higaki, Toshio Ogihara
American Journal of Physiology - Regulatory Integrative and Comparative Physiology Vol. 271 No. 5 p. R1212-R1220 1996年11月 研究論文(学術雑誌)
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Fusigenic viral liposome for gene therapy in cardiovascular diseases
VJ Dzau, MJ Mann, R Morishita, Y Kaneda
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA Vol. 93 No. 21 p. 11421-11425 1996年10月 研究論文(学術雑誌)
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In vivo transfer of gene and oligodeoxynucleotides into skin of fetal rats by incubation in amniotic fluid
SI Hayashi, R Morishita, M Aoki, A Moriguchi, Kida, I, M Nakajima, Y Kaneda, J Higaki, T Ogihara
GENE THERAPY Vol. 3 No. 10 p. 878-885 1996年10月 研究論文(学術雑誌)
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Characterization of in vivo gene transfer into the arterial wall mediated by the sendai virus (Hemagglutinating virus of Japan) liposomes: An effective tool for the in vivo study of arterial diseases
Y Yonemitsu, Y Kaneda, R Morishita, K Nakagawa, Y Nakashima, K Sueishi
LABORATORY INVESTIGATION Vol. 75 No. 3 p. 313-323 1996年9月 研究論文(学術雑誌)
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Fusigenic liposome-mediated DNA transfer into cardiac myocytes
KE Ellison, NH Bishopric, KA Webster, R Morishita, GH Gibbons, Y Kaneda, B Sato, VJ Dzau
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY Vol. 28 No. 7 p. 1385-1399 1996年7月 研究論文(学術雑誌)
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Sustained transgene expression by transfection of renin gene into liver of neonates
N Tomita, R Morishita, J Higaki, S Tomita, M Aoki, Y Kaneda, T Ogihara
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS Vol. 224 No. 1 p. 43-49 1996年7月 研究論文(学術雑誌)
-
Expression of full-length human dystrophin cDNA in mdx mouse muscle by HVJ-liposome injection
I. Yanagihara, K. Inui, G. Dickson, G. Turner, T. Piper, Y. Kaneda, S. Okada
Gene Therapy Vol. 3 No. 6 p. 549-553 1996年6月 研究論文(学術雑誌)
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Autocrine paracrine effects of overexpression of hepatocyte growth factor gene on growth of endothelial cells
S Hayashi, R Morishita, J Higaki, M Aoki, A Moriguchi, Kida, I, S Yoshiki, K Matsumoto, T Nakamura, Y Kaneda, T Ogihara
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS Vol. 220 No. 3 p. 539-545 1996年3月 研究論文(学術雑誌)
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Preparation of laminin-related peptide analogs and their inhibitory effect on experimental metastasis in mice
Y Izuno, M Kakiuchi, M Maeda, K Kawasaki, Y Kaneda, Y Tsutsumi, S Nakagawa, T Mayumi
PEPTIDE CHEMISTRY 1995 p. 401-404 1996年 研究論文(国際会議プロシーディングス)
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Inhibition of TGF-β1 expression by antisense oligonucleotides suppressed extracellular matrix accumulation in experimental glomerulonephritis
Yoshitaka Akagi, Yoshitaka Isaka, Makoto Arai, Tetsuya Kaneko, Masaru Takenaka, Toshiki Moriyama, Yasufumi Kaneda, Akio Ando, Yoshimasa Orita, Takenobu Kamada, Naohiko Ueda, Enyu Imai
Kidney International Vol. 50 No. 1 p. 148-155 1996年 研究論文(学術雑誌)
出版者・発行元:Nature Publishing Group
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Gene therapy by skeletal muscle expression of decorin prevents fibrotic disease in rat kidney
Yoshitaka Isaka, Douglas K. Brees, Kazuko Ikegaya, Yasufumi Kaneda, Enyu Imai, Nancy A. Noble, Wayne A. Border
Nature Medicine Vol. 2 No. 4 p. 418-423 1996年 研究論文(学術雑誌)
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Novel strategy of gene therapy in cardiovascular disease with HVJ-liposome method
R Morishita, J Higaki, M Aoki, S Hayashi, Kida, I, Y Kaneda, T Ogihara
PROGRESSION OF CHRONIC RENAL DISEASES Vol. 118 p. 254-264 1996年 研究論文(国際会議プロシーディングス)
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Transient introduction of a foreign gene into healing rat patellar ligament
N Nakamura, S Horibe, N Matsumoto, T Tomita, T Natsuume, Y Kaneda, K Shino, T Ochi
JOURNAL OF CLINICAL INVESTIGATION Vol. 97 No. 1 p. 226-231 1996年1月 研究論文(学術雑誌)
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Role of transcriptional cis-elements, angiotensinogen gene-activating elements, of angiotensinogen gene in blood pressure regulation.
Morishita R, Higaki J, Tomita N, Aoki M, Moriguchi A, Tamura K, Murakami K, Kaneda Y, Ogihara T
Hypertension Vol. 27 p. 502-507 1996年 研究論文(学術雑誌)
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Effect of angiotensinogen on blood pressure regulation in normotensive rats: Application of a loss of function approach
N Tomita, R Morishita, J Higaki, S Tomita, M Aoki, Y Kaneda, T Ogihara
JOURNAL OF HYPERTENSION Vol. 13 No. 12 p. 1767-1774 1995年12月 研究論文(学術雑誌)
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The loss of 40-kDa chromosomal protein in tuberous sclerosis lesions
M WatayaKaneda, K Hashimoto, K Yoshikawa, Y Kaneda
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS Vol. 217 No. 2 p. 599-607 1995年12月 研究論文(学術雑誌)
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EFFICIENCY OF IN-VIVO GENE TRANSFECTION INTO TRANSPLANTED RAT-HEART BY CORONARY INFUSION OF HVJ LIPOSOME
Y SAWA, K SUZUKI, HZ BAI, R SHIRAKURA, R MORISHITA, Y KANEDA, H MATSUDA
CIRCULATION Vol. 92 No. 9 p. 479-482 1995年11月 研究論文(学術雑誌)
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Overexpression of Prostacyclin Synthase Inhibits Growth of Vascular Smooth Muscle Cells
Shuntaro Hara, Ryuichi Morishita, Yoshinori Tone, Chieko Yokoyama, Hiroyasu Inoue, Yasufumi Kaneda, Toshio Ogihara, Tadashi Tanabe
Biochemical and Biophysical Research Communications Vol. 216 p. 862-867 1995年1月1日
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EVIDENCE FOR DIRECT LOCAL EFFECT OF ANGIOTENSIN IN VASCULAR HYPERTROPHY - IN-VIVO GENE-TRANSFER OF ANGIOTENSIN-CONVERTING ENZYME
R MORISHITA, GH GIBBONS, KE ELLISON, W LEE, LN ZHANG, H YU, Y KANEDA, T OGIHARA, VJ DZAU
JOURNAL OF CLINICAL INVESTIGATION Vol. 94 No. 3 p. 978-984 1994年9月 研究論文(学術雑誌)
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AUTOCRINE AND PARACRINE EFFECTS OF ATRIAL-NATRIURETIC-PEPTIDE GENE-TRANSFER ON VASCULAR SMOOTH-MUSCLE AND ENDOTHELIAL CELLULAR GROWTH
R MORISHITA, GH GIBBONS, RE PRATT, N TOMITA, Y KANEDA, T OGIHARA, VJ DZAU
JOURNAL OF CLINICAL INVESTIGATION Vol. 94 No. 2 p. 824-829 1994年8月 研究論文(学術雑誌)
-
Introduction and expression of human CD59 gene in the canine kidney
T. Akami, K. Arakawa, M. Okamoto, K. Akioka, I. Fujiwara, I. Nakai, M. Mitsuo, N. Tomita, Y. Kaneda, K. Tanaka, T. Oka
Transplantation Proceedings Vol. 26 No. 3 p. 1315-1317 1994年 研究論文(国際会議プロシーディングス)
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A novel gene-transfer technique mediated by HVJ (Sendai Virus), nuclear protein, and liposomes.
Tomita, N, Higaki, J, Ogihara, T, Kondo, T, Kaneda, Y
Can. Det. and Prev. Vol. 18 No. 6 p. 485-491 1994年 研究論文(学術雑誌)
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Construction of radiation-reduced hybrids and their use in mapping of microclones from chromosome 10p11.2-q11.2
Shoichi Fujita, Eisei Shin, Tsutomu Nakamura, Hiroki Kurahashi, Yasufumi Kaneda, Kiyoji Tanaka, Takesada Mori, Shin-ichiro Takai, Isamu Nishisho
The Japanese Journal of Human Genetics Vol. 38 No. 4 p. 361-370 1993年12月 研究論文(学術雑誌)
出版者・発行元:Springer-Verlag
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HYPERTENSIVE RATS PRODUCED BY IN-VIVO INTRODUCTION OF THE HUMAN RENIN GENE
N TOMITA, J HIGAKI, Y KANEDA, H YU, R MORISHITA, H MIKAMI, T OGIHARA
CIRCULATION RESEARCH Vol. 73 No. 5 p. 898-905 1993年11月 研究論文(学術雑誌)
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SINGLE INTRALUMINAL DELIVERY OF ANTISENSE CDC2 KINASE AND PROLIFERATING-CELL NUCLEAR ANTIGEN OLIGONUCLEOTIDES RESULTS IN CHRONIC INHIBITION OF NEOINTIMAL HYPERPLASIA
R MORISHITA, GH GIBBONS, KE ELLISON, M NAKAJIMA, L ZHANG, Y KANEDA, T OGIHARA, VJ DZAU
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA Vol. 90 No. 18 p. 8474-8478 1993年9月 研究論文(学術雑誌)
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NOVEL AND EFFECTIVE GENE-TRANSFER TECHNIQUE FOR STUDY OF VASCULAR RENIN-ANGIOTENSIN SYSTEM
R MORISHITA, GH GIBBONS, Y KANEDA, T OGIHARA, VJ DZAU
JOURNAL OF CLINICAL INVESTIGATION Vol. 91 No. 6 p. 2580-2585 1993年6月 研究論文(学術雑誌)
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NOVEL INVITRO GENE-TRANSFER METHOD FOR STUDY OF LOCAL MODULATORS IN VASCULAR SMOOTH-MUSCLE CELLS
R MORISHITA, GH GIBBONS, Y KANEDA, T OGIHARA, VJ DZAU
HYPERTENSION Vol. 21 No. 6 p. 894-899 1993年6月 研究論文(学術雑誌)
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Transfection of Interleukin 2 Gene into Human Melanoma Cells Augments Cellular Immune Response
Akihiko Uchiyama, Dave S. B. Hoon, Takashi Morisaki, Yasufumi Kaneda, Dale H. Yuzuki, Donald L. Morton
Cancer Research Vol. 53 No. 5 p. 949-952 1993年3月1日 研究論文(学術雑誌)
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Implementation of a Parallel Processing System for Inference of Phylogenetic Trees“jointly authored”
松田秀雄
280-283 p. 280-283 1993年 研究論文(国際会議プロシーディングス)
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Glomerulosclerosis induced by in vivo transfection of transforming growth factor-β or platelet-derived growth factor gene into the rat kidney
Yoshitaka Isaka, Yoshihiro Fujiwara, Naohiko Ueda, Yasufumi Kaneda, Takenobu Kamada, Enyu Imai
Journal of Clinical Investigation Vol. 92 No. 6 p. 2597-2601 1993年 研究論文(学術雑誌)
出版者・発行元:The American Society for Clinical Investigation
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ANTISENSE OLIGONUCLEOTIDES DIRECTED AT CELL-CYCLE REGULATORY GENES AS STRATEGY FOR RESTENOSIS THERAPY
R MORISHITA, GH GIBBONS, KE ELLISON, M NAKAJIMA, H VONDERLEYEN, LN ZHANG, Y KANEDA, T OGIHARA, VJ DZAU
TRANSACTIONS OF THE ASSOCIATION OF AMERICAN PHYSICIANS, VOL 106 Vol. 106 p. 54-61 1993年 研究論文(国際会議プロシーディングス)
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DIRECT INVIVO GENE INTRODUCTION INTO RAT-KIDNEY
N TOMITA, J HIGAKI, R MORISHITA, K KATO, H MIKAMI, Y KANEDA, T OGIHARA
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS Vol. 186 No. 1 p. 129-134 1992年7月 研究論文(学術雑誌)
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Monoclonal antibodies specific for human chromosome 5 obtained with a monochromosomal hybrid can be used to sort out cells containing the chromosome with a FACS
Akihiro Yoneda, Yoshihiro Yoneda, Yasufumi Kaneda, Helene Hayes, Tsuyoshi Uchida, Yoshio Okada
Chromosoma Vol. 100 No. 3 p. 187-192 1991年3月 研究論文(学術雑誌)
出版者・発行元:Springer-Verlag
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A case of Fabry's disease in a patient with no α-galactosidase A activity caused by a single amino acid substitution of Pro-40 by Ser
Tsuyoshi Koide, Masahiro Ishiura, Kunimitu Iwai, Michitoshi Inoue, Yasufumi Kaneda, Yoshio Okada, Tsuyoshi Uchida
FEBS Letters Vol. 259 No. 2 p. 353-356 1990年1月1日 研究論文(学術雑誌)
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INTRODUCTION OF DOSIM PREDICATE TO PROLOG
Y KANEDA, H MATSUDA
NEW GENERATION COMPUTING Vol. 8 No. 2 p. 163-181 1990年 研究論文(学術雑誌)
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Secretion of mr 46,000 protein from human hepatoma cells treated with tumor promotors is regulated by c-myc gene expression
Hiroshi Miwatani, Yoshihiro Yoneda, Yasufumi Kaneda, Tsuyoshi Uchida, Hideo Maki, Tsuyoshi Uchida
Cell Structure and Function Vol. 14 No. 2 p. 183-192 1989年 研究論文(学術雑誌)
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Regional assignment of the gene for diphtheria toxin sensitivity using subchromosomal fragments in microcell hybrids
Hélène Hayes, Yasufumi Kaneda, Tsuyoshi Uchida, Yoshio Okada
Chromosoma Vol. 96 No. 1 p. 26-32 1987年12月 研究論文(学術雑誌)
出版者・発行元:Springer-Verlag
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Immunofluorescence analysis of cultured mammalian cell nucleus using four monoclonal antibodies against the nucleus
Mari Wataya-Kaneda, Kiyoshi Nishioka, Yasufumi Kaneda, Tsuyoshi Uchida
Journal of Dermatology Vol. 14 No. 4 p. 316-321 1987年8月1日 研究論文(学術雑誌)
出版者・発行元:Blackwell Publishing Ltd
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A monoclonal antibody against the nucleus reveals the presence of a common protein in the nuclear envelope, the perichromosomal region, and cytoplasmic vesicles
M. Wataya-Kaneda, Y. Kaneda, T. Sakurai, H. Sugawa, T. Uchida
Journal of Cell Biology Vol. 104 No. 1 p. 1-7 1987年 研究論文(学術雑誌)
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Parallel Prolog Machine PARK : Its Hardware Structure and Prolog System“jointly authored”
松田秀雄
221/ Vol. 221 p. 35-43 1986年 研究論文(学術雑誌)