EN

基本情報

研究

社会活動

その他の活動

伊川 正人

Ikawa Masahito

微生物病研究所,教授

keyword 受精,発生生物学,実験動物学,発生工学,生殖生物学

学歴

  • 1994年04月 ~ 1997年03月,大阪大学,薬学研究科,環境生物薬学
  • ~ 1992年03月,大阪大学,薬学部,薬学科

経歴

  • 2012年11月 ~ 継続中,大阪大学,教授
  • 2004年04月 ~ 2012年10月,大阪大学,助教授
  • 1998年07月 ~ 2004年03月,大阪大学,助手
  • 2000年09月 ~ 2002年09月,米国ソーク研究所,博士研究員
  • 1997年04月 ~ 1998年06月,日本学術振興会,特別研究員(PD)
  • 1994年04月 ~ 1997年03月,日本学術振興会 特別研究員(DC)

研究内容・専門分野

  • ライフサイエンス,発生生物学,受精
  • ライフサイエンス,分子生物学,ゲノム編集
  • ライフサイエンス,実験動物学,生殖工学

所属学会

  • 日本ゲノム編集学会
  • アメリカ生殖生物学会
  • 日本生殖免疫学会
  • 日本実験動物学会
  • 日本繁殖生物学会
  • アメリカ遺伝子治療学会
  • 日本分子生物学会
  • 日本アンドロロジー学会

論文

  • Bi-allelic DNAH8 Variants Lead to Multiple Morphological Abnormalities of the Sperm Flagella and Primary Male Infertility,Chunyu Liu,Haruhiko Miyata,Yang Gao,Yanwei Sha,Shuyan Tang,Zoulan Xu,Marjorie Whitfield,Catherine Patrat,Huan Wu,Emmanuel Dulioust,Shixiong Tian,Keisuke Shimada,Jiangshan Cong,Taichi Noda,Hang Li,Akane Morohoshi,Caroline Cazin,Zine Eddine Kherraf,Christophe Arnoult,Li Jin,Xiaojin He,Pierre F. Ray,Yunxia Cao,Aminata Touré,Feng Zhang,Masahito Ikawa,American Journal of Human Genetics,Vol. 107,No. 2,p. 330-341,2020年08月06日,研究論文(学術雑誌)
  • NELL2-mediated lumicrine signaling through OVCH2 is required for male fertility,Daiji Kiyozumi,Taichi Noda,Ryo Yamaguchi,Tomohiro Tobita,Takafumi Matsumura,Kentaro Shimada,Mayo Kodani,Takashi Kohda,Yoshitaka Fujihara,Manabu Ozawa,Zhifeng Yu,Gabriella Miklossy,Kurt M. Bohren,Masato Horie,Masaru Okabe,Martin M. Matzuk,Masahito Ikawa,Science,Vol. 368,No. 6495,p. 1132-1135,2020年06月05日,研究論文(学術雑誌)
  • Sperm proteins SOF1, TMEM95, and SPACA6 are required for sperm-oocyte fusion in mice,Taichi Noda,Yonggang Lu,Yoshitaka Fujihara,Seiya Oura,Takayuki Koyano,Sumire Kobayashi,Martin M. Matzuk,Masahito Ikawa,Proceedings of the National Academy of Sciences of the United States of America,Proceedings of the National Academy of Sciences,Vol. 117,No. 21,p. 11493-11502,2020年05月26日,研究論文(学術雑誌)
  • Spermatozoa lacking Fertilization Influencing Membrane Protein (FIMP) fail to fuse with oocytes in mice,Yoshitaka Fujihara,Yonggang Lu,Taichi Noda,Asami Oji,Tamara Larasati,Kanako Kojima-Kita,Zhifeng Yu,Ryan M. Matzuk,Martin M. Matzuk,Masahito Ikawa,Proceedings of the National Academy of Sciences of the United States of America,Vol. 117,No. 17,p. 9393-9400,2020年04月,研究論文(学術雑誌)
  • Identification of multiple male reproductive tractspecific proteins that regulate sperm migration through the oviduct in mice,Yoshitaka Fujihara,Taichi Noda,Kiyonori Kobayashi,Asami Oji,Sumire Kobayashi,Takafumi Matsumura,Tamara Larasati,Seiya Oura,Kanako Kojima-Kita,Zhifeng Yu,Martin M. Matzuk,Masahito Ikawa,Proceedings of the National Academy of Sciences of the United States of America,Vol. 116,No. 37,p. 18498-18506,2019年09月10日,研究論文(学術雑誌)
  • Engineered CRISPR-Cas9 nuclease with expanded targeting space,Hiroshi Nishimasu,Xi Shi,Soh Ishiguro,Linyi Gao,Seiichi Hirano,Sanae Okazaki,Taichi Noda,Omar O. Abudayyeh,Jonathan S. Gootenberg,Hideto Mori,Seiya Oura,Benjamin Holmes,Mamoru Tanaka,Motoaki Seki,Hisato Hirano,Hiroyuki Aburatani,Ryuichiro Ishitani,Masahito Ikawa,Nozomu Yachie,Feng Zhang,Osamu Nureki,Science,Vol. 361,No. 6408,p. 1259-1262,2018年,研究論文(学術雑誌)
  • Genome engineering uncovers 54 evolutionarily conserved and testis-enriched genes that are not required for male fertility in mice,Haruhiko Miyata,Julio M. Castaneda,Yoshitaka Fujihara,Zhifeng Yu,Denise R. Archambeault,Ayako Isotani,Daiji Kiyozumi,Maya L. Kriseman,Daisuke Mashiko,Takafumi Matsumura,Ryan M. Matzuk,Masashi Mori,Taichi Noda,Asami Oji,Masaru Okabe,Renata Prunskaite-Hyyrylainen,Ramiro Ramirez-Solis,Yuhkoh Satouh,Qian Zhang,Masahito Ikawa,Martin M. Matzuk,Proceedings of the National Academy of Sciences of the United States of America,NATL ACAD SCIENCES,Vol. 113,No. 28,p. 7704-7710,2016年07月12日,研究論文(学術雑誌)
  • Sperm calcineurin inhibition prevents mouse fertility with implications for male contraceptive,Haruhiko Miyata,Yuhkoh Satouh,Daisuke Mashiko,Masanaga Muto,Kaori Nozawa,Kogiku Shiba,Yoshitaka Fujihara,Ayako Isotani,Kazuo Inaba,Masahito Ikawa,Science,AMER ASSOC ADVANCEMENT SCIENCE,Vol. 350,No. 6259,p. 442-445,2015年10月23日,研究論文(学術雑誌)
  • MiR-200b and miR-429 function in mouse ovulation and are essential for female fertility,Hidetoshi Hasuwa,Jun Ueda,Masahito Ikawa,Masaru Okabe,Science,American Association for the Advancement of Science,Vol. 341,No. 6141,p. 71-73,2013年,研究論文(学術雑誌)
  • Protein disulfide isomerase homolog PDILT is required for quality control of sperm membrane protein ADAM3 and male infertility,Keizo Tokuhiro,Masahito Ikawa,Adam M. Benham,Masaru Okabe,Proceedings of the National Academy of Sciences of the United States of America,NATL ACAD SCIENCES,Vol. 109,No. 10,p. 3850-3855,2012年03月06日,研究論文(学術雑誌)
  • Pravastatin induces placental growth factor (PGF) and ameliorates preeclampsia in a mouse model,Keiichi Kumasawa,Masahito Ikawa,Hiroyasu Kidoya,Hidetoshi Hasuwa,Tomoko Saito-Fujita,Yuka Morioka,Nobuyuki Takakura,Tadashi Kimura,Masaru Okabe,Proceedings of the National Academy of Sciences of the United States of America,NATL ACAD SCIENCES,Vol. 108,No. 4,p. 1451-1455,2011年01月,研究論文(学術雑誌)
  • Fertilization: A sperm's journey to and interaction with the oocyte,Masahito Ikawa,Naokazu Inoue,Adam M. Benham,Masaru Okabe,Journal of Clinical Investigation,AMER SOC CLINICAL INVESTIGATION INC,Vol. 120,No. 4,p. 984-994,2010年04月
  • Complementation of placental defects and embryonic lethality by trophoblast-specific lentiviral gene transfer,Yuka Okada,Yuko Ueshin,Ayako Isotani,Tomoko Saito-Fujita,Hisako Nakashima,Kazushi Kimura,Akira Mizoguchi,Masatsugu Oh-Hora,Yoshiko Mori,Masato Ogata,Robert G. Oshima,Masaru Okabe,Masahito Ikawa,Nature Biotechnology,NATURE PUBLISHING GROUP,Vol. 25,No. 2,p. 233-237,2007年02月,研究論文(学術雑誌)
  • The immunoglobulin superfamily protein Izumo is required for sperm to fuse with eggs,Naokazu Inoue,Masahito Ikawa,Ayako Isotani,Masaru Okabe,Nature,NATURE PUBLISHING GROUP,Vol. 434,No. 7030,p. 234-238,2005年03月10日,研究論文(学術雑誌)
  • Restoration of spermatogenesis by lentiviral gene transfer: Offspring from infertile mice,Masahito Ikawa,Vinay Tergaonkar,Atsuo Ogura,Narumi Ogonuki,Kimiko Inoue,Inder M. Verma,Proceedings of the National Academy of Sciences of the United States of America,NATL ACAD SCIENCES,Vol. 99,No. 11,p. 7524-7529,2002年05月28日,研究論文(学術雑誌)
  • The putative chaperone calmegin is required for sperm fertility,Masahito Ikawa,Ikuo Wada,Katsuya Kominami,Daisuke Watanabe,Kiyotaka Toshimori,Yoshitake Nishimune,Masaru Okabe,Nature,MACMILLAN MAGAZINES LTD,Vol. 387,No. 6633,p. 607-610,1997年06月05日,研究論文(学術雑誌)
  • Identification and characterization of the antigen recognized by the germ cell mAb TRA98 using a human comprehensive wet protein array,Eriko Fukuda,Hiromitsu Tanaka,Kei Yamaguchi,Mieko Takasaka,Yoshifumi Kawamura,Hidenobu Okuda,Ayako Isotani,Masahito Ikawa,Virginia Smith Shapiro,Junji Tsuchida,Yuki Okada,Akira Tsujimura,Yasushi Miyagawa,Shinichiro Fukuhara,Yoshitaka Kawakami,Morimasa Wada,Yoshitake Nishimune,Naoki Goshima,Genes to Cells,Vol. 26,No. 3,p. 180-189,2021年03月,研究論文(学術雑誌)
  • Cooperation-based sperm clusters mediate sperm oviduct entry and fertilization,Yongcun Qu,Qi Chen,Shanshan Guo,Chiyuan Ma,Yonggang Lu,Junchao Shi,Shichao Liu,Tong Zhou,Taichi Noda,Jingjing Qian,Liwen Zhang,Xili Zhu,Xiaohua Lei,Yujing Cao,Wei Li,Wei Li,Nicolas Plachta,Martin M. Matzuk,Masahito Ikawa,Enkui Duan,Ying Zhang,Hongmei Wang,Protein and Cell,2021年
  • Structural insights into tetraspanin CD9 function,Rie Umeda,Yuhkoh Satouh,Mizuki Takemoto,Yoshiko Nakada-Nakura,Kehong Liu,Takeshi Yokoyama,Mikako Shirouzu,So Iwata,Norimichi Nomura,Ken Sato,Masahito Ikawa,Tomohiro Nishizawa,Osamu Nureki,Nature Communications,Vol. 11,No. 1,p. 1606-1606,2020年12月01日,研究論文(学術雑誌)
  • IgSF11 regulates osteoclast differentiation through association with the scaffold protein PSD-95,Hyunsoo Kim,Noriko Takegahara,Matthew C. Walsh,Sarah A. Middleton,Jiyeon Yu,Jumpei Shirakawa,Jun Ueda,Yoshitaka Fujihara,Masahito Ikawa,Masaru Ishii,Junhyong Kim,Yongwon Choi,Bone Research,Vol. 8,No. 1,2020年12月01日,研究論文(学術雑誌)
  • CRISPR/CAS9-mediated amino acid substitution reveals phosphorylation residues of RSPH6A are not essential for male fertility in mice†,Haruhiko Miyata,Ferheen Abbasi,Pablo E. Visconti,Masahito Ikawa,Biology of reproduction,Vol. 103,No. 5,p. 912-914,2020年10月29日,研究論文(学術雑誌)
  • PGAP6, a GPI-specific phospholipase A2, has narrow substrate specificity against GPI-anchored proteins,Gun Hee Lee,Morihisa Fujita,Hideki Nakanishi,Haruhiko Miyata,Masahito Ikawa,Yusuke Maeda,Yoshiko Murakami,Taroh Kinoshita,The Journal of biological chemistry,Vol. 295,No. 42,p. 14501-14509,2020年10月16日,研究論文(学術雑誌)
  • Evidence for lysosomal biogenesis proteome defect and impaired autophagy in preeclampsia,Akitoshi Nakashima,Shi Bin Cheng,Masahito Ikawa,Tamotsu Yoshimori,Warren J. Huber,Ramkumar Menon,Zheping Huang,Jamie Fierce,James F. Padbury,Yoel Sadovsky,Shigeru Saito,Surendra Sharma,Autophagy,Vol. 16,No. 10,p. 1771-1785,2020年10月02日,研究論文(学術雑誌)
  • Diphtheria toxin-mediated transposon-driven poly (A)-trapping efficiently disrupts transcriptionally silent genes in embryonic stem cells,Jie Bai,Ryohei Kondo,N. Ika Mayasari,Toshiaki Shigeoka,Ayako Isotani,Masahito Ikawa,Goro Sashida,Masashi Kawaichi,Yasumasa Ishida,Genesis,Wiley,Vol. 58,No. 9,2020年09月01日,研究論文(学術雑誌)
  • Protocadherin-7 contributes to maintenance of bone homeostasis through regulation of osteoclast multinucleation,Hyunsoo Kim,Noriko Takegahara,Matthew C. Walsh,Jun Ueda,Yoshitaka Fujihara,Masahito Ikawa,Yongwon Choi,BMB Reports,Vol. 53,No. 9,p. 472-477,2020年09月01日,研究論文(学術雑誌)
  • Large-scale discovery of male reproductive tract-specific genes through analysis of RNA-seq datasets,Matthew J. Robertson,Katarzyna Kent,Nathan Tharp,Kaori Nozawa,Laura Dean,Michelle Mathew,Sandra L. Grimm,Zhifeng Yu,Christine Légaré,Yoshitaka Fujihara,Masahito Ikawa,Robert Sullivan,Cristian Coarfa,Martin M. Matzuk,Thomas X. Garcia,BMC Biology,Vol. 18,No. 1,2020年08月19日,研究論文(学術雑誌)
  • Knockout of serine-rich single-pass membrane protein 1 (Ssmem1) causes globozoospermia and sterility in male mice,Kaori Nozawa,Qian Zhang,Haruhiko Miyata,Darius J. Devlin,Zhifeng Yu,Seiya Oura,Takayuki Koyano,Makoto Matsuyama,Masahito Ikawa,Martin M. Matzuk,Biology of Reproduction,Vol. 103,No. 2,p. 244-253,2020年08月01日,研究論文(国際会議プロシーディングス)
  • CIB4 is essential for the haploid phase of spermatogenesis in mice,Zoulan Xu,Haruhiko Miyata,Yuki Kaneda,Julio M. Castaneda,Yonggang Lu,Akane Morohoshi,Zhifeng Yu,Martin M. Matzuk,Masahito Ikawa,Biology of Reproduction,Vol. 103,No. 2,p. 235-243,2020年08月01日,研究論文(国際会議プロシーディングス)
  • Tmprss12 is required for sperm motility and uterotubal junction migration in mice,Tamara Larasati,Taichi Noda,Yoshitaka Fujihara,Keisuke Shimada,Tomohiro Tobita,Zhifeng Yu,Martin M. Matzuk,Masahito Ikawa,Biology of Reproduction,Vol. 103,No. 2,p. 254-263,2020年08月01日,研究論文(国際会議プロシーディングス)
  • CRISPR/Cas9-mediated genome-edited mice reveal 10 testis-enriched genes are dispensable for male fecundity,Soojin Park,Keisuke Shimada,Yoshitaka Fujihara,Zoulan Xu,Kentaro Shimada,Tamara Larasati,Putri Pratiwi,Ryan M. Matzuk,Darius J. Devlin,Zhifeng Yu,Thomas X. Garcia,Martin M. Matzuk,Masahito Ikawa,Biology of Reproduction,Vol. 103,No. 2,p. 195-204,2020年08月01日,研究論文(国際会議プロシーディングス)
  • Knockout of family with sequence similarity 170 member A (Fam170a) causes male subfertility, while Fam170b is dispensable in mice,Darius J. Devlin,Kaori Nozawa,Masahito Ikawa,Martin M. Matzuk,Biology of Reproduction,Vol. 103,No. 2,p. 205-222,2020年08月01日,研究論文(国際会議プロシーディングス)
  • CRISPR/Cas9-based genome editing in mice uncovers 13 testis- or epididymis-enriched genes individually dispensable for male reproduction,Jiang Sun,Yonggang Lu,Kaori Nozawa,Zoulan Xu,Akane Morohoshi,Julio M. Castaneda,Taichi Noda,Haruhiko Miyata,Ferheen Abbasi,Hossam H. Shawki,Satoru Takahashi,Darius J. Devlin,Zhifeng Yu,Ryan M. Matzuk,Thomas X. Garcia,Martin M. Matzuk,Masahito Ikawa,Biology of Reproduction,Vol. 103,No. 2,p. 183-194,2020年08月01日,研究論文(国際会議プロシーディングス)
  • Prss55 but not Prss51 is required for male fertility in mice,Kiyonori Kobayashi,Tsutomu Endo,Takafumi Matsumura,Yonggang Lu,Zhifeng Yu,Martin M. Matzuk,Masahito Ikawa,Biology of Reproduction,Vol. 103,No. 2,p. 223-234,2020年08月01日,研究論文(国際会議プロシーディングス)
  • PHF7 Modulates BRDT Stability and Histone-to-Protamine Exchange during Spermiogenesis,Chang Rok Kim,Taichi Noda,Hyunkyung Kim,Gibeom Kim,Seongwan Park,Yongwoo Na,Seiya Oura,Keisuke Shimada,Injin Bang,Jun Yeong Ahn,Yong Ryoul Kim,Se Kyu Oh,Hee Jung Choi,Jong Seo Kim,Inkyung Jung,Ho Lee,Yuki Okada,Masahito Ikawa,Sung Hee Baek,Cell Reports,Vol. 32,No. 4,2020年07月28日,研究論文(学術雑誌)
  • Reduction in BDNF from inefficient precursor conversion influences nest building and promotes depressive-like behavior in mice,Masami Kojima,Hikari Otabi,Haruko Kumanogoh,Atsushi Toyoda,Masahito Ikawa,Masaru Okabe,Toshiyuki Mizui,International Journal of Molecular Sciences,Vol. 21,No. 11,2020年06月01日,研究論文(学術雑誌)
  • Identification of transmembrane protein 168 mutation in familial Brugada syndrome,Akio Shimizu,Dimitar P. Zankov,Akira Sato,Masahiro Komeno,Futoshi Toyoda,Satoru Yamazaki,Toshinori Makita,Taichi Noda,Masahito Ikawa,Yoshihiro Asano,Yohei Miyashita,Seiji Takashima,Hiroshi Morita,Taisuke Ishikawa,Naomasa Makita,Masahito Hitosugi,Hiroshi Matsuura,Seiko Ohno,Minoru Horie,Hisakazu Ogita,FASEB Journal,Vol. 34,No. 5,p. 6399-6417,2020年05月01日,研究論文(学術雑誌)
  • Tesmin, Metallothionein-Like 5, is Required for Spermatogenesis in Mice,Asami Oji,Ayako Isotani,Yoshitaka Fujihara,Julio M. Castaneda,Seiya Oura,Masahito Ikawa,Biology of Reproduction,Vol. 102,No. 4,p. 975-983,2020年04月,研究論文(学術雑誌)
  • Testis-enriched kinesin KIF9 is important for progressive motility in mouse spermatozoa,Haruhiko Miyata,Keisuke Shimada,Akane Morohoshi,Seiya Oura,Takafumi Matsumura,Zoulan Xu,Yuki Oyama,Masahito Ikawa,FASEB Journal,Vol. 34,No. 4,p. 5389-5400,2020年04月,研究論文(学術雑誌)
  • Mouse t-complex protein 11 is important for progressive motility in sperm,Julio M. Castaneda,Haruhiko Miyata,Denise R. Archambeault,Yuhkoh Satouh,Zhifeng Yu,Masahito Ikawa,Martin M. Matzuk,Biology of Reproduction,Vol. 102,No. 4,p. 852-862,2020年04月,研究論文(学術雑誌)
  • CRISPR/Cas9-Mediated Genome Editing Reveals Oosp Family Genes are Dispensable for Female Fertility in Mice,Ferheen Abbasi,Mayo Kodani,Chihiro Emori,Daiji Kiyozumi,Masashi Mori,Yoshitaka Fujihara,Masahito Ikawa,Cells,Vol. 9,No. 4,2020年03月28日,研究論文(学術雑誌)
  • The testis-specific serine proteases PRSS44, PRSS46, and PRSS54 are dispensable for male mouse fertility,Richard J. Holcomb,Seiya Oura,Kaori Nozawa,Katarzyna Kent,Zhifeng Yu,Matthew J. Robertson,Cristian Coarfa,Martin M. Matzuk,Masahito Ikawa,Thomas X. Garcia,Biology of Reproduction,Vol. 102,No. 1,p. 84-91,2020年02月12日,研究論文(学術雑誌)
  • Genetic loss of importin α4 causes abnormal sperm morphology and impacts on male fertility in mouse,Yoichi Miyamoto,Mitsuho Sasaki,Haruhiko Miyata,Yoko Monobe,Masahiro Nagai,Mayumi Otani,Penny A.F. Whiley,Akane Morohoshi,Shinya Oki,Junichiro Matsuda,Ken ichi Akagi,Jun Adachi,Masaru Okabe,Masahito Ikawa,Yoshihiro Yoneda,Kate L. Loveland,Masahiro Oka,FASEB Journal,2020年,研究論文(学術雑誌)
  • RNA-binding protein ptbp1 regulates alternative splicing and transcriptome in spermatogonia and maintains spermatogenesis in concert with nanos3,Manami Senoo,Hiroshi Hozoji,Yu Ishikawa-Yamauchi,Takashi Takijiri,Sho Ohta,Tomoyo Ukai,Mio Kabata,Takuya Yamamoto,Yasuhiro Yamada,Masahito Ikawa,Manabu Ozawa,Journal of Reproduction and Development,Vol. 66,No. 5,p. 459-467,2020年,研究論文(学術雑誌)
  • Nexin-Dynein regulatory complex component DRC7 but not FBXL13 is required for sperm flagellum formation and male fertility in mice,Akane Morohoshi,Haruhiko Miyata,Keisuke Shimada,Kaori Nozawa,Takafumi Matsumura,Ryuji Yanase,Kogiku Shiba,Kazuo Inaba,Masahito Ikawa,PLoS Genetics,Vol. 16,No. 1,2020年,研究論文(学術雑誌)
  • PITHD1 is a proteasome-interacting protein essential for male fertilization,Hiroyuki Kondo,X. Takafumi Matsumura,Mari Kaneko,Kenichi Inoue,Hidetaka Kosako,Masahito Ikawa,Yousuke Takahama,Izumi Ohigashi,Journal of Biological Chemistry,Vol. 295,No. 6,p. 1658-1672,2020年,研究論文(学術雑誌)
  • Dgkg knock-out mice show impairments in cerebellar motor coordination, Ltd, and the dendritic development of purkinje cells through the activation of pkcg,Ryosuke Tsumagari,Sho Kakizawa,Sakiko Kikunaga,Yoshitaka Fujihara,Shuji Ueda,Minoru Yamanoue,Naoaki Saito,Masahito Ikawa,Yasuhito Shirai,eNeuro,Society for Neuroscience,Vol. 7,No. 2,p. ENEURO.0319-19.2020,2020年,研究論文(学術雑誌)
  • Analysis of the sperm flagellar axoneme using gene-modified mice,Haruhiko Miyata,Akane Morohoshi,Masahito Ikawa,Experimental Animals,Vol. 69,No. 4,p. 374-381,2020年
  • Genetic mutation of Frem3 does not cause fraser syndrome in mice,Daiji Kiyozumi,Masashi Mori,Mayo Kodani,Masahito Ikawa,Experimental Animals,Vol. 69,No. 1,p. 104-109,2020年,研究論文(学術雑誌)
  • Polarized PtdIns(4,5)P<inf>2</inf> distribution mediated by a voltage-sensing phosphatase (VSP) regulates sperm motility,Takafumi Kawai,Haruhiko Miyata,Hiroki Nakanishi,Souhei Sakata,Shin Morioka,Junko Sasaki,Masahiko Watanabe,Kenji Sakimura,Toyoshi Fujimoto,Takehiko Sasaki,Masahito Ikawa,Yasushi Okamura,Proceedings of the National Academy of Sciences of the United States of America,Vol. 116,No. 51,p. 26020-26028,2019年12月17日,研究論文(学術雑誌)
  • Rap1 regulates hematopoietic stem cell survival and affects oncogenesis and response to chemotherapy,Ekta Khattar,Kyaw Ze Ya Maung,Chen Li Chew,Arkasubhra Ghosh,Michelle Meng Huang Mok,Pei Lee,Jun Zhang,Wei Hong Jeff Chor,Gökhan Cildir,Chelsia Qiuxia Wang,Nur Khairiah Mohd-Ismail,Desmond Wai Loon Chin,Soo Chin Lee,Henry Yang,Yong Jae Shin,Do Hyun Nam,Liming Chen,Alan Prem Kumar,Lih Wen Deng,Masahito Ikawa,Jayantha Gunaratne,Motomi Osato,Vinay Tergaonkar,Nature Communications,Vol. 10,No. 1,p. 5349-5349,2019年12月01日,研究論文(学術雑誌)
  • Male mice, caged in the International Space Station for 35 days, sire healthy offspring,Takafumi Matsumura,Taichi Noda,Masafumi Muratani,Risa Okada,Mutsumi Yamane,Ayako Isotani,Takashi Kudo,Satoru Takahashi,Masahito Ikawa,Scientific Reports,Vol. 9,No. 1,2019年12月01日,研究論文(学術雑誌)
  • Cutting edge: Role of MASP-3 in the physiological activation of factor D of the alternative complement pathway,Manabu Hayashi,Takeshi Machida,Yumi Ishida,Yusuke Ogata,Tomoko Omori,Mika Takasumi,Yuichi Endo,Toshiyuki Suzuki,Masayuki Sekimata,Yoshimi Homma,Masahito Ikawa,Hiromasa Ohira,Teizo Fujita,Hideharu Sekine,Journal of Immunology,Vol. 203,No. 6,p. 1411-1416,2019年09月15日,研究論文(学術雑誌)
  • CRISPR/Cas9-mediated genome editing reveals 30 testis-enriched genes dispensable for male fertility in mice†.,Lu Y,Oura S,Matsumura T,Oji A,Sakurai N,Fujihara Y,Shimada K,Miyata H,Tobita T,Noda T,Castaneda JM,Kiyozumi D,Zhang Q,Larasati T,Young SAM,Kodani M,Huddleston CA,Robertson MJ,Coarfa C,Isotani A,Aitken RJ,Okabe M,Matzuk MM,Garcia TX,Ikawa M,Biology of reproduction,Vol. 101,No. 2,p. 501-511,2019年08月01日,研究論文(学術雑誌)
  • Erratum: Publisher Correction: Calaxin is required for cilia-driven determination of vertebrate laterality (Communications biology (2019) 2 (226)),Keita Sasaki,Kogiku Shiba,Akihiro Nakamura,Natsuko Kawano,Yuhkoh Satouh,Hiroshi Yamaguchi,Motohiro Morikawa,Daisuke Shibata,Ryuji Yanase,Kei Jokura,Mami Nomura,Mami Miyado,Shuji Takada,Hironori Ueno,Shigenori Nonaka,Tadashi Baba,Masahito Ikawa,Masahide Kikkawa,Kenji Miyado,Kazuo Inaba,Communications biology,Vol. 2,No. 1,2019年07月04日,研究論文(学術雑誌)
  • GPAT2 is required for piRNA biogenesis, transposon silencing, and maintenance of spermatogonia in mice†.,Shiromoto Y,Kuramochi-Miyagawa S,Nagamori I,Chuma S,Arakawa T,Nishimura T,Hasuwa H,Tachibana T,Ikawa M,Nakano T,Biology of reproduction,Vol. 101,No. 1,p. 248-256,2019年07月01日,研究論文(学術雑誌)
  • Physiological function of seminal vesicle secretions on male fecundity,Taichi Noda,Masahito Ikawa,Reproductive Medicine and Biology,Vol. 18,No. 3,p. 241-246,2019年07月
  • Calaxin is required for cilia-driven determination of vertebrate laterality,Keita Sasaki,Kogiku Shiba,Akihiro Nakamura,Natsuko Kawano,Yuhkoh Satouh,Hiroshi Yamaguchi,Motohiro Morikawa,Daisuke Shibata,Ryuji Yanase,Kei Jokura,Mami Nomura,Mami Miyado,Shuji Takada,Hironori Ueno,Shigenori Nonaka,Tadashi Baba,Masahito Ikawa,Masahide Kikkawa,Kenji Miyado,Kazuo Inaba,Communications biology,Vol. 2,No. 1,2019年06月20日,研究論文(学術雑誌)
  • Mice with Calr mutations homologous to human CALR mutations only exhibit mild thrombocytosis,Kotaro Shide,Takuro Kameda,Ayako Kamiunten,Asami Oji,Yoshinori Ozono,Masaaki Sekine,Arata Honda,Akira Kitanaka,Keiichi Akizuki,Yuki Tahira,Kenichi Nakamura,Tomonori Hidaka,Yoko Kubuki,Hiroo Abe,Tadashi Miike,Hisayoshi Iwakiri,Yoshihiro Tahara,Mitsue Sueta,Satoru Hasuike,Shojiro Yamamoto,Kenji Nagata,Masahito Ikawa,Kazuya Shimoda,Blood Cancer Journal,Vol. 9,No. 4,2019年04月,研究論文(学術雑誌)
  • USP15 participates in hepatitis C virus propagation through regulation of viral RNA translation and lipid droplet formation,Shinji Kusakabe,Tatsuya Suzuki,Yukari Sugiyama,Saori Haga,Kanako Horike,Makoto Tokunaga,Junki Hirano,He Zhang,David Virya Chen,Hanako Ishiga,Yasumasa Komoda,Chikako Ono,Takasuke Fukuhara,Masahiro Yamamoto,Masahito Ikawa,Takashi Satoh,Shizuo Akira,Tomohisa Tanaka,Kohji Moriishi,Moto Fukai,Akinobu Taketomi,Sachiyo Yoshio,Tatsuya Kanto,Tetsuro Suzuki,Toru Okamoto,Yoshiharu Matsuura,Journal of Virology,Vol. 93,No. 6,2019年03月01日,研究論文(学術雑誌)
  • Developmental analyses of mouse embryos and adults using a non-overlapping tracing system for all three germ layers,Takashi Serizawa,Ayako Isotani,Takafumi Matsumura,Katsuyuki Nakanishi,Shigenori Nonaka,Shinsuke Shibata,Masahito Ikawa,Hideyuki Okano,Development (Cambridge),Vol. 146,No. 21,2019年,研究論文(学術雑誌)
  • Nine genes abundantly expressed in the epididymis are not essential for male fecundity in mice,T. Noda,N. Sakurai,K. Nozawa,S. Kobayashi,D. J. Devlin,M. M. Matzuk,M. Ikawa,Andrology,Vol. 7,No. 5,p. 644-653,2019年,研究論文(学術雑誌)
  • CKAP4, a DKK1 receptor, is a biomarker in exosomes derived from pancreatic cancer and a molecular target for therapy,Hirokazu Kimura,Hideki Yamamoto,Takeshi Harada,Katsumi Fumoto,Yoshihito Osugi,Ryota Sada,Natsumi Maehara,Hayato Hikita,Soichiro Mori,Hidetoshi Eguchi,Masahito Ikawa,Tetsuo Takehara,Akira Kikuchi,Clinical Cancer Research,Vol. 25,No. 6,p. 1936-1947,2019年,研究論文(学術雑誌)
  • PTBP1 contributes to spermatogenesis through regulation of proliferation in spermatogonia,Manami Senoo,Takashi Takijiri,Nobuaki Yoshida,Manabu Ozawa,Masahito Ikawa,Journal of Reproduction and Development,Vol. 65,No. 1,p. 37-46,2019年,研究論文(学術雑誌)
  • Lvrn expression is not critical for mouse placentation,Tomohiro Tobita,Daiji Kiyozumi,Masanaga Muto,Taichi Noda,Masahito Ikawa,Journal of Reproduction and Development,Vol. 65,No. 3,p. 239-244,2019年,研究論文(学術雑誌)
  • Ventricular–subventricular zone fractones are speckled basement membranes that function as a neural stem cell niche,Yuya Sato,Daiji Kiyozumi,Sugiko Futaki,Itsuko Nakano,Chisei Shimono,Naoko Kaneko,Masahito Ikawa,Masaru Okabe,Kazunobu Sawamoto,Kiyotoshi Sekiguchi,Molecular Biology of the Cell,Vol. 30,No. 1,p. 56-68,2019年01月01日,研究論文(学術雑誌)
  • An azoospermic factor gene, Ddx3y and its paralog, Ddx3x are dispensable in germ cells for male fertility,Takafumi Matsumura,Tsutomu Endo,Ayako Isotani,Masaki Ogawa,Masahito Ikawa,Journal of Reproduction and Development,Vol. 65,No. 2,p. 121-128,2019年,研究論文(学術雑誌)
  • Glycerol kinase 2 is essential for proper arrangement of crescent-like mitochondria to form the mitochondrial sheath during mouse spermatogenesis,Keisuke Shimada,Hirotaka Kato,Haruhiko Miyata,Masahito Ikawa,Journal of Reproduction and Development,Vol. 65,No. 2,p. 155-162,2019年,研究論文(学術雑誌)
  • Seminal vesicle secretory protein 7, PATE4, is not required for sperm function but for copulatory plug formation to ensure fecundity,Taichi Noda,Yoshitaka Fujihara,Takafumi Matsumura,Seiya Oura,Sumire Kobayashi,Masahito Ikawa,Biology of Reproduction,Vol. 100,No. 4,p. 1035-1045,2019年,研究論文(学術雑誌)
  • Chimeric analysis with newly established EGFP/DsRed2-tagged ES cells identify HYDIN as essential for spermiogenesis in mice,Seiya Oura,Haruhiko Miyata,Taichi Noda,Keisuke Shimada,Takafumi Matsumura,Akane Morohoshi,Ayako Isotani,Masahito Ikawa,Experimental Animals,Vol. 68,No. 1,p. 25-34,2019年,研究論文(学術雑誌)
  • Calaxin is required for cilia-driven determination of vertebrate laterality.,Keita Sasaki,Kogiku Shiba,Akihiro Nakamura,Natsuko Kawano,Yuhkoh Satouh,Hiroshi Yamaguchi,Motohiro Morikawa,Daisuke Shibata,Ryuji Yanase,Kei Jokura,Mami Nomura,Mami Miyado,Shuji Takada,Hironori Ueno,Shigenori Nonaka,Tadashi Baba,Masahito Ikawa,Masahide Kikkawa,Kenji Miyado,Kazuo Inaba,Communications biology,Vol. 2,p. 226-226,2019年,研究論文(学術雑誌)
  • Sperm-borne phospholipase C zeta-1 ensures monospermic fertilization in mice,Kaori Nozawa,Yuhkoh Satouh,Takao Fujimoto,Asami Oji,Masahito Ikawa,Scientific Reports,Nature Publishing Group,Vol. 8,No. 1,2018年12月01日,研究論文(学術雑誌)
  • Impaired male fertility and abnormal epididymal epithelium differentiation in mice lacking CRISP1 and CRISP4,Guillermo Carvajal,Nicolás Gastón Brukman,Mariana Weigel Muñoz,María A. Battistone,Vanesa A. Guazzone,Masahito Ikawa,Miyata Haruhiko,Livia Lustig,Sylvie Breton,Patricia S. Cuasnicu,Scientific Reports,Vol. 8,No. 1,2018年12月01日,研究論文(学術雑誌)
  • Trophoblast-Specific Conditional Atg7 Knockout Mice Develop Gestational Hypertension,Aiko Aoki,Akitoshi Nakashima,Tae Kusabiraki,Yosuke Ono,Osamu Yoshino,Masanaga Muto,Keiichi Kumasawa,Tamotsu Yoshimori,Masahito Ikawa,Shigeru Saito,American Journal of Pathology,Vol. 188,No. 11,p. 2474-2486,2018年11月,研究論文(学術雑誌)
  • RSPH6A is required for sperm flagellum formation and male fertility in mice,Ferheen Abbasi,Haruhiko Miyata,Keisuke Shimada,Akane Morohoshi,Kaori Nozawa,Takafumi Matsumura,Zoulan Xu,Putri Pratiwi,Masahito Ikawa,Journal of Cell Science,Vol. 131,No. 19,2018年10月01日,研究論文(学術雑誌)
  • Co-expression of sperm membrane proteins CMTM2A and CMTM2B is essential for ADAM3 localization and male fertility in mice,Yoshitaka Fujihara,Asami Oji,Kanako Kojima-Kita,Tamara Larasati,Masahito Ikawa,Journal of Cell Science,Vol. 131,No. 19,2018年10月01日,研究論文(学術雑誌)
  • New Insights into the Molecular Events of Mammalian Fertilization,Yuhkoh Satouh,Masahito Ikawa,Trends in Biochemical Sciences,Vol. 43,No. 10,p. 818-828,2018年10月
  • Infection with flaviviruses requires BCLX<inf>L</inf> for cell survival,Tatsuya Suzuki,Toru Okamoto,Hiroshi Katoh,Yukari Sugiyama,Shinji Kusakabe,Makoto Tokunaga,Junki Hirano,Yuka Miyata,Takasuke Fukuhara,Masahito Ikawa,Takashi Satoh,Sachiyo Yoshio,Ryosuke Suzuki,Masayuki Saijo,David C.S. Huang,Tatsuya Kanto,Shizuo Akira,Yoshiharu Matsuura,PLoS Pathogens,Vol. 14,No. 9,2018年09月,研究論文(学術雑誌)
  • mDia1/3 generate cortical F-actin meshwork in Sertoli cells that is continuous with contractile F-actin bundles and indispensable for spermatogenesis and male fertility,Satoko Sakamoto,Dean Thumkeo,Hiroshi Ohta,Zhen Zhang,Shuangru Huang,Pakorn Kanchanawong,Takayoshi Fuu,Sadanori Watanabe,Kentaro Shimada,Yoshitaka Fujihara,Shosei Yoshida,Masahito Ikawa,Naoki Watanabe,Mitinori Saitou,Shuh Narumiya,PLoS Biology,Vol. 16,No. 9,2018年09月,研究論文(学術雑誌)
  • Correction: Two Ck1δ transcripts regulated by m6A meth-ylation code for two antagonistic kinases in the control of the circadian clock (Proceedings of the National Academy of Sciences of the United States of America (2018) 115 (5980-5985) DOI: 10.1073/pnas.1721371115),Jean Michel Fustin,Rika Kojima,Kakeru Itoh,Hsin Yi Chang,Shiqi Ye,Bowen Zhuang,Asami Oji,Shingo Gibo,Rajesh Narasimamurthy,David Virshup,Gen Kurosawa,Masao Doi,Ichiro Manabe,Yasushi Ishihama,Masahito Ikawa,Hitoshi Okamura,Proceedings of the National Academy of Sciences of the United States of America,Vol. 115,No. 27,2018年07月03日,研究論文(学術雑誌)
  • Two <i>Ck1δ</i> transcripts regulated by m6A methylation code for two antagonistic kinases in the control of the circadian clock.,Fustin JM,Kojima R,Itoh K,Chang HY,Ye S,Zhuang B,Oji A,Gibo S,Narasimamurthy R,Virshup D,Kurosawa G,Doi M,Manabe I,Ishihama Y,Ikawa M,Okamura H,Proceedings of the National Academy of Sciences of the United States of America,National Academy of Sciences,Vol. 115,No. 23,p. 5980-5985,2018年06月05日,研究論文(学術雑誌)
  • Intravesicular acidification regulates lipopolysaccharide inflammation and tolerance through TLR4 trafficking,Motoya Murase,Takumi Kawasaki,Rika Hakozaki,Takuya Sueyoshi,Dyaningtyas Dewi Pamungkas Putri,Yuichi Kitai,Shintaro Sato,Masahito Ikawa,Taro Kawai,Journal of Immunology,American Association of Immunologists,Vol. 200,No. 8,p. 2798-2808,2018年04月,研究論文(学術雑誌)
  • Transgenic mouse lines expressing the 3xFLAG-dCas9 protein for enChIP analysis,Toshitsugu Fujita,Fusako Kitaura,Asami Oji,Naoki Tanigawa,Miyuki Yuno,Masahito Ikawa,Ichiro Taniuchi,Hodaka Fujii,Genes to Cells,Blackwell Publishing Ltd,Vol. 23,No. 4,p. 318-325,2018年04月,研究論文(学術雑誌)
  • Tropomyosin 2 heterozygous knockout in mice using CRISPR-Cas9 system displays the inhibition of injury-induced epithelial-mesenchymal transition, and lens opacity,Teppei Shibata,Shinsuke Shibata,Yasuhito Ishigaki,Etsuko Kiyokawa,Masahito Ikawa,Dhirendra P. Singh,Hiroshi Sasaki,Eri Kubo,Mechanisms of Ageing and Development,Elsevier Ireland Ltd,Vol. 171,p. 24-30,2018年04月,研究論文(学術雑誌)
  • MARCKSL1 Regulates Spine Formation in the Amygdala and Controls the Hypothalamic-Pituitary-Adrenal Axis and Anxiety-Like Behaviors,Takashi Tanaka,Shoko Shimizu,Masaki Ueno,Yoshitaka Fujihara,Masahito Ikawa,Shingo Miyata,EBioMedicine,Elsevier B.V.,Vol. 30,p. 62-73,2018年04月,研究論文(学術雑誌)
  • Factors controlling sperm migration through the oviduct revealed by gene-modified mouse models,Yoshitaka Fujihara,Haruhiko Miyata,Masahito Ikawa,Experimental Animals,International Press Editing Centre Incorporation,Vol. 67,No. 2,p. 91-104,2018年
  • Revolutionizing male fertility factor research in mice by using the genome editing tool CRISPR/Cas9,Ferheen Abbasi,Haruhiko Miyata,Masahito Ikawa,Reproductive Medicine and Biology,John Wiley and Sons Ltd,Vol. 17,No. 1,p. 3-10,2018年01月
  • Laminin γ1 C-terminal Glu to Gln mutation induces early postimplantation lethality.,Kiyozumi D,Taniguchi Y,Nakano I,Toga J,Yagi E,Hasuwa H,Ikawa M,Sekiguchi K,Life science alliance,Vol. 1,No. 5,2018年,研究論文(学術雑誌)
  • Sperm defects,Julio M. Castañeda,Haruhiko Miyata,Masahito Ikawa,Martin M. Matzuk,Encyclopedia of Reproduction,No. 4,p. 276-281,2018年01月01日,論文集(書籍)内論文
  • Vestigial-like 2 contributes to normal muscle fiber type distribution in mice,Masahiko Honda,Kyoko Hidaka,So Ichiro Fukada,Ryo Sugawa,Manabu Shirai,Masahito Ikawa,Takayuki Morisaki,Scientific Reports,NATURE PUBLISHING GROUP,Vol. 7,No. 1,2017年12月01日,研究論文(学術雑誌)
  • Modification of single-nucleotide polymorphism in a fully humanized CYP3A mouse by genome editing technology,Satoshi Abe,Kaoru Kobayashi,Asami Oji,Tetsushi Sakuma,Kanako Kazuki,Shoko Takehara,Kazuomi Nakamura,Azusa Okada,Yasuko Tsukazaki,Naoto Senda,Kazuhisa Honma,Takashi Yamamoto,Masahito Ikawa,Kan Chiba,Mitsuo Oshimura,Yasuhiro Kazuki,Scientific Reports,NATURE PUBLISHING GROUP,Vol. 7,No. 1,2017年12月01日,研究論文(学術雑誌)
  • Suppression of HBV replication by the expression of nickase-and nuclease dead-Cas9,Takeshi Kurihara,Takasuke Fukuhara,Chikako Ono,Satomi Yamamoto,Kentaro Uemura,Toru Okamoto,Masaya Sugiyama,Daisuke Motooka,Shota Nakamura,Masato Ikawa,Masashi Mizokami,Yoshihiko Maehara,Yoshiharu Matsuura,Scientific Reports,NATURE PUBLISHING GROUP,Vol. 7,No. 1,2017年12月01日,研究論文(学術雑誌)
  • Placenta-specific gene manipulation using lentiviral vector and its application,Tomohiro Tobita,Daiji Kiyozumi,Masahito Ikawa,Placenta,W B SAUNDERS CO LTD,Vol. 59,No. Suppl 1,p. S37-S43,2017年11月,研究論文(学術雑誌)
  • Human globozoospermia-related gene spata16 is required for sperm formation revealed by CRISPR/Cas9-mediated mouse models,Yoshitaka Fujihara,Asami Oji,Tamara Larasati,Kanako Kojima-Kita,Masahito Ikawa,International Journal of Molecular Sciences,MDPI AG,Vol. 18,No. 10,2017年10月21日,研究論文(学術雑誌)
  • TCTE1 is a conserved component of the dynein regulatory complex and is required for motility and metabolism in mouse spermatozoa,Julio M. Castaneda,Rong Hua,Haruhiko Miyata,Asami Oji,Yueshuai Guo,Yiwei Cheng,Tao Zhou,Xuejiang Guo,Yiqiang Cui,Bin Shen,Zibin Wang,Zhibin Hu,Zuomin Zhou,Jiahao Sha,Renata Prunskaite-Hyyrylainen,Zhifeng Yu,Ramiro Ramirez-Solis,Masahito Ikawa,Martin M. Matzuk,Mingxi Liu,Proceedings of the National Academy of Sciences of the United States of America,NATL ACAD SCIENCES,Vol. 114,No. 27,p. E5370-E5378,2017年07月03日,研究論文(学術雑誌)
  • New insights into the role of Jmjd3 and Utx in axial skeletal formation in mice,Chie Naruse,Shinwa Shibata,Masaru Tamura,Takayuki Kawaguchi,Kanae Abe,Kazushi Sugihara,Tomoaki Kato,Takumi Nishiuchi,Shigeharu Wakana,Masahito Ikawa,Masahide Asano,FASEB Journal,FEDERATION AMER SOC EXP BIOL,Vol. 31,No. 6,p. 2252-2266,2017年06月,研究論文(学術雑誌)
  • BATF2 inhibits immunopathological Th17 responses by suppressing Il23a expression during Trypanosoma cruzi infection,Shoko Kitada,Hisako Kayama,Daisuke Okuzaki,Ritsuko Koga,Masao Kobayashi,Yasunobu Arima,Atsushi Kumanogoh,Masaaki Murakami,Masahito Ikawa,Kiyoshi Takeda,Journal of Experimental Medicine,ROCKEFELLER UNIV PRESS,Vol. 214,No. 5,p. 1313-1331,2017年05月01日,研究論文(学術雑誌)
  • The mechanics clarifying counterclockwise rotation in most IVF eggs in mice,Kenta Ishimoto,Masahito Ikawa,Masaru Okabe,Scientific Reports,NATURE PUBLISHING GROUP,Vol. 7,2017年03月03日,研究論文(学術雑誌)
  • Viable offspring after imaging of Ca2+ oscillations and visualization of the cortical reaction in mouse eggs†.,Satouh Y,Nozawa K,Yamagata K,Fujimoto T,Ikawa M,Biol Reprod.,SOC STUDY REPRODUCTION,Vol. 96,No. 3,p. 563-575,2017年03月01日,研究論文(学術雑誌)
  • Proton pump inhibitors decrease soluble fms-like tyrosine kinase-1 and soluble endoglin secretion, decrease hypertension, and rescue endothelial dysfunction,Kenji Onda,Stephen Tong,Sally Beard,Natalie Binder,Masanaga Muto,Sevvandi N. Senadheera,Laura Parry,Mark Dilworth,Lewis Renshall,Fiona Brownfoot,Roxanne Hastie,Laura Tuohey,Kirsten Palmer,Toshihiko Hirano,Masahito Ikawa,Tu'uhevaha Kaitu'u-Lino,Natalie J. Hannan,Hypertension,LIPPINCOTT WILLIAMS & WILKINS,Vol. 69,No. 3,p. 457-468,2017年03月01日,研究論文(学術雑誌)
  • Regulation of intestinal homeostasis by the ulcerative colitis-Associated gene RNF186,Kosuke Fujimoto,Makoto Kinoshita,Hiroo Tanaka,Daisuke Okuzaki,Yosuke Shimada,Hisako Kayama,Ryu Okumura,Yoki Furuta,Masashi Narazaki,Atsushi Tamura,Shigetsugu Hatakeyama,Masahito Ikawa,Kiichiro Tsuchiya,Mamoru Watanabe,Atsushi Kumanogoh,Sachiko Tsukita,Kiyoshi Takeda,Mucosal Immunology,NATURE PUBLISHING GROUP,Vol. 10,No. 2,p. 446-459,2017年03月01日,研究論文(学術雑誌)
  • Testis-Specific Histone Variant H3t Gene Is Essential for Entry into Spermatogenesis,Jun Ueda,Akihito Harada,Takashi Urahama,Shinichi Machida,Kazumitsu Maehara,Masashi Hada,Yoshinori Makino,Jumpei Nogami,Naoki Horikoshi,Akihisa Osakabe,Hiroyuki Taguchi,Hiroki Tanaka,Hiroaki Tachiwana,Tatsuma Yao,Minami Yamada,Takashi Iwamoto,Ayako Isotani,Masahito Ikawa,Taro Tachibana,Yuki Okada,Hiroshi Kimura,Yasuyuki Ohkawa,Hitoshi Kurumizaka,Kazuo Yamagata,Cell Reports,CELL PRESS,Vol. 18,No. 3,p. 593-600,2017年01月17日,研究論文(学術雑誌)
  • Muscle-specific deletion of BDK amplifies loss of myofibrillar protein during protein undernutrition,Takuya Ishikawa,Yasuyuki Kitaura,Yoshihiro Kadota,Yukako Morishita,Miki Ota,Fumiya Yamanaka,Minjun Xu,Masahito Ikawa,Naokazu Inoue,Fuminori Kawano,Naoya Nakai,Taro Murakami,Shinji Miura,Yukino Hatazawa,Yasutomi Kamei,Yoshiharu Shimomura,Scientific Reports,NATURE PUBLISHING GROUP,Vol. 7,2017年01月04日,研究論文(学術雑誌)
  • Mouse spermatozoa with higher fertilization rates have thinner nuclei,Daisuke Mashiko,Masahito Ikawa,Koichi Fujimoto,PeerJ,PEERJ INC,Vol. 2017,No. 10,2017年,研究論文(学術雑誌)
  • A delayed sperm penetration of cumulus layers by disruption of acrosin gene in rats<sup>†</sup>,Ayako Isotani,Takafumi Matsumura,Masaki Ogawa,Takahiro Tanaka,Kazuo Yamagata,Masahito Ikawa,Masaru Okabe,Biology of Reproduction,OXFORD UNIV PRESS INC,Vol. 97,No. 1,p. 61-68,2017年,研究論文(学術雑誌)
  • Genome editing in mouse zygotes and embryonic stem cells by introducing SgRNA/Cas9 expressing plasmids,Taichi Noda,Asami Oji,Masahito Ikawa,Methods in Molecular Biology,Humana Press Inc.,Vol. 1630,p. 67-80,2017年,論文集(書籍)内論文
  • STING in tumor and host cells cooperatively work for NK cell-mediated tumor growth retardation,Ken Takashima,Yohei Takeda,Hiroyuki Oshiumi,Hiroaki Shime,Masaru Okabe,Masahito Ikawa,Misako Matsumoto,Tsukasa Seya,Biochemical and Biophysical Research Communications,ACADEMIC PRESS INC ELSEVIER SCIENCE,Vol. 478,No. 4,p. 1764-1771,2016年09月30日,研究論文(学術雑誌)
  • CRISPR/Cas9 mediated genome editing in ES cells and its application for chimeric analysis in mice,Asami Oji,Taichi Noda,Yoshitaka Fujihara,Haruhiko Miyata,Yeon Joo Kim,Masanaga Muto,Kaori Nozawa,Takafumi Matsumura,Ayako Isotani,Masahito Ikawa,Scientific Reports,NATURE PUBLISHING GROUP,Vol. 6,2016年08月17日,研究論文(学術雑誌)
  • Structural and functional insights into IZUMO1 recognition by JUNO in mammalian fertilization,Kazuki Kato,Yuhkoh Satouh,Hiroshi Nishimasu,Arisa Kurabayashi,Junko Morita,Yoshitaka Fujihara,Asami Oji,Ryuichiro Ishitani,Masahito Ikawa,Osamu Nureki,Nature Communications,NATURE PUBLISHING GROUP,Vol. 7,2016年07月15日,研究論文(学術雑誌)
  • Essential role of autoactivation circuitry on Aurora B-mediated H2AX-pS121 in mitosis,Midori Shimada,Takahiro Goshima,Hiromi Matsuo,Yoshikazu Johmura,Mayumi Haruta,Kazuhiro Murata,Hiromitsu Tanaka,Masahito Ikawa,Keiko Nakanishi,Makoto Nakanishi,Nature Communications,NATURE PUBLISHING GROUP,Vol. 7,2016年07月08日,研究論文(学術雑誌)
  • Regulation of intestinal homeostasis by the ulcerative colitis-associated gene RNF186.,Fujimoto K,Kinoshita M,Tamura A,Tanaka H,Okuzaki D,Shimada Y,Kayama H,Okumura R,Furuta Y,Narazaki M,Hatakeyama S,Ikawa M,Tsuchiya K,Watanabe M,Kumanogoh A,Tsukita S,Takeda K,Mucosal Immunol.,2016年07月,研究論文(学術雑誌)
  • Biogenesis of sperm acrosome is regulated by pre-mRNA alternative splicing of acrbp in the mouse,Yoshinori Kanemori,Yoshitaka Koga,Mai Sudo,Woojin Kang,Shin Ichi Kashiwabara,Masahito Ikawa,Hidetoshi Hasuwa,Kiyoshi Nagashima,Yu Ishikawa,Narumi Ogonuki,Atsuo Ogura,Tadashi Baba,Proceedings of the National Academy of Sciences of the United States of America,NATL ACAD SCIENCES,Vol. 113,No. 26,p. E3696-E3705,2016年06月28日,研究論文(学術雑誌)
  • Complementary role of CNNM2 in sperm motility and Ca<sup>2+</sup> influx during capacitation,Daisuke Yamazaki,Yosuke Funato,Haruhiko Miyata,Masahito Ikawa,Hiroaki Miki,Biochemical and Biophysical Research Communications,ACADEMIC PRESS INC ELSEVIER SCIENCE,Vol. 474,No. 3,p. 441-446,2016年06月03日,研究論文(学術雑誌)
  • Expression of a Synthetic Gene of CTDM by Transgenic Animals,R. Sakai,A. Maeda,R. Matsuura,H. Eguchi,P. Lo,H. Hasuwa,M. Ikawa,K. Nakahata,M. Zenitani,T. Yamamichi,S. Umeda,H. Okuyama,S. Miyagawa,Transplantation Proceedings,ELSEVIER SCIENCE INC,Vol. 48,No. 4,p. 1279-1281,2016年05月01日,研究論文(国際会議プロシーディングス)
  • Knockout of Cytidine Monophospho-N-Acetylneuraminic Acid (CMP-NeuAc) Hydroxylase from Porcine Endothelial Cells by a CRISPR System,R. Sakai,Y. Esaki,H. Hasuwa,M. Ikawa,P. Lo,R. Matsuura,K. Nakahata,M. Zenitani,M. Asada,A. Maeda,H. Eguchi,H. Okuyama,S. Miyagawa,Transplantation Proceedings,ELSEVIER SCIENCE INC,Vol. 48,No. 4,p. 1320-1322,2016年05月01日,研究論文(国際会議プロシーディングス)
  • Human HLA-Ev (147) Expression in Transgenic Animals,R. Matsuura,A. Maeda,R. Sakai,H. Eguchi,P. -C. Lo,H. Hasuwa,M. Ikawa,K. Nakahata,M. Zenitani,T. Yamamichi,S. Umeda,K. Deguchi,H. Okuyama,S. Miyagawa,TRANSPLANTATION PROCEEDINGS,ELSEVIER SCIENCE INC,Vol. 48,No. 4,p. 1323-1325,2016年05月,研究論文(学術雑誌)
  • Kidney-specific knockout of Sav1 in the mouse promotes hyperproliferation of renal tubular epithelium through suppression of the Hippo pathway,Tomoki Kai,Yoshiyuki Tsukamoto,Naoki Hijiya,Akinori Tokunaga,Chisato Nakada,Tomohisa Uchida,Tsutomu Daa,Hidekatsu Iha,Mika Takahashi,Takeo Nomura,Fuminori Sato,Hiromitsu Mimata,Masahito Ikawa,Masao Seto,Keiko Matsuura,Masatsugu Moriyama,JOURNAL OF PATHOLOGY,WILEY,Vol. 239,No. 1,p. 97-108,2016年05月,研究論文(学術雑誌)
  • Kidney-specific knockout of Sav1 in the mouse promotes hyperproliferation of renal tubular epithelium through suppression of the Hippo pathway,Tomoki Kai,Yoshiyuki Tsukamoto,Naoki Hijiya,Akinori Tokunaga,Chisato Nakada,Tomohisa Uchida,Tsutomu Daa,Hidekatsu Iha,Mika Takahashi,Takeo Nomura,Fuminori Sato,Hiromitsu Mimata,Masahito Ikawa,Masao Seto,Keiko Matsuura,Masatsugu Moriyama,Journal of Pathology,Vol. 239,No. 1,p. 97-108,2016年05月01日,研究論文(学術雑誌)
  • Kidney-specific knockout of Sav1 in the mouse promotes hyperproliferation of renal tubular epithelium through suppression of the Hippo pathway,Tomoki Kai,Yoshiyuki Tsukamoto,Naoki Hijiya,Akinori Tokunaga,Chisato Nakada,Tomohisa Uchida,Tsutomu Daa,Hidekatsu Iha,Mika Takahashi,Takeo Nomura,Fuminori Sato,Hiromitsu Mimata,Masahito Ikawa,Masao Seto,Keiko Matsuura,Masatsugu Moriyama,JOURNAL OF PATHOLOGY,WILEY,Vol. 239,No. 1,p. 97-108,2016年05月,研究論文(学術雑誌)
  • Expression of a Synthetic Gene of CTDM by Transgenic Animals,R. Sakai,A. Maeda,R. Matsuura,H. Eguchi,P. Lo,H. Hasuwa,M. Ikawa,K. Nakahata,M. Zenitani,T. Yamamichi,S. Umeda,H. Okuyama,S. Miyagawa,TRANSPLANTATION PROCEEDINGS,ELSEVIER SCIENCE INC,Vol. 48,No. 4,p. 1279-1281,2016年05月,研究論文(学術雑誌)
  • Knockout of Cytidine Monophospho-N-Acetylneuraminic Acid (CMP-NeuAc) Hydroxylase From Porcine Endothelial Cells by a CRISPR System,R. Sakai,Y. Esaki,H. Hasuwa,M. Ikawa,P. Lo,R. Matsuura,K. Nakahata,M. Zenitani,M. Asada,A. Maeda,H. Eguchi,H. Okuyama,S. Miyagawa,TRANSPLANTATION PROCEEDINGS,ELSEVIER SCIENCE INC,Vol. 48,No. 4,p. 1320-1322,2016年05月,研究論文(学術雑誌)
  • Human HLA-Ev (147) Expression in Transgenic Animals,R. Matsuura,A. Maeda,R. Sakai,H. Eguchi,P. C. Lo,H. Hasuwa,M. Ikawa,K. Nakahata,M. Zenitani,T. Yamamichi,S. Umeda,K. Deguchi,H. Okuyama,S. Miyagawa,Transplantation Proceedings,ELSEVIER SCIENCE INC,Vol. 48,No. 4,p. 1323-1325,2016年05月01日,研究論文(国際会議プロシーディングス)
  • The Mg<sup>2+</sup> transporter CNNM4 regulates sperm Ca<sup>2+</sup> homeostasis and is essential for reproduction,Daisuke Yamazaki,Haruhiko Miyata,Yosuke Funato,Yoshitaka Fujihara,Masahito Ikawa,Hiroaki Miki,Journal of Cell Science,COMPANY OF BIOLOGISTS LTD,Vol. 129,No. 9,p. 1940-1949,2016年05月01日,研究論文(学術雑誌)
  • Calreticulin Regulates Neointima Formation and Collagen Deposition following Carotid Artery Ligation,Kurt A. Zimmerman,Dongqi Xing,Manuel A. Pallero,Ailing Lu,Masahito Ikawa,Leland Black,Kenneth L. Hoyt,Janusz H. Kabarowski,Marek Michalak,Joanne E. Murphy-Ullrich,Journal of Vascular Research,KARGER,Vol. 52,No. 5,p. 306-320,2016年04月,研究論文(学術雑誌)
  • Generation of Hprt-disrupted rat through mouse←rat ES chimeras.,Isotani A,Yamagata K,Okabe M,Ikawa M,Sci Rep.,NATURE PUBLISHING GROUP,Vol. 6,2016年04月,研究論文(学術雑誌)
  • Fertilization defects in sperm from Cysteine-rich secretory protein 2 (Crisp2) knockout mice: implications for fertility disorders,N. G. Brukman,H. Miyata,P. Torres,D. Lombardo,J. J. Caramelo,M. Ikawa,V. G. Da Ros,P. S. Cuasnicu,MOLECULAR HUMAN REPRODUCTION,OXFORD UNIV PRESS,Vol. 22,No. 4,p. 240-251,2016年04月,研究論文(学術雑誌)
  • Behavior of mouse spermatozoa in the female reproductive tract from soon after mating to the beginning of fertilization,Yuko Muro,Hidetoshi Hasuwa,Ayako Isotani,Haruhiko Miyata,Kazuo Yamagata,Masahito Ikawa,Ryuzo Yanagimachi,Masaru Okabe,Biology of Reproduction,SOC STUDY REPRODUCTION,Vol. 94,No. 4,p. 1193-1207,2016年04月,研究論文(学術雑誌)
  • Fertilization defects in sperm from Cysteine-rich secretory protein 2 (Crisp2) knockout mice: Implications for fertility disorders,N. G. Brukman,H. Miyata,P. Torres,D. Lombardo,J. J. Caramelo,M. Ikawa,V. G. Da Ros,P. S. Cuasnicú,Molecular Human Reproduction,OXFORD UNIV PRESS,Vol. 22,No. 4,p. 240-251,2016年04月,研究論文(学術雑誌)
  • GPI-AP release in cellular, developmental, and reproductive biology,Yoshitaka Fujihara,Masahito Ikawa,Journal of Lipid Research,AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC,Vol. 57,No. 4,p. 538-545,2016年04月
  • CABYR is essential for fibrous sheath integrity and progressive motility in mouse spermatozoa,Samantha A.M. Young,Haruhiko Miyata,Yuhkoh Satouh,Robert John Aitken,Mark A. Baker,Masahito Ikawa,Journal of Cell Science,COMPANY OF BIOLOGISTS LTD,Vol. 129,No. 23,p. 4379-4387,2016年,研究論文(学術雑誌)
  • CRISPR/CAS9-mediated mutation revealed cytoplasmic tail is dispensable for IZUMO1 function and male fertility,Samantha A.M. Young,Haruhiko Miyata,Yuhkoh Satouh,Masanaga Muto,Martin R. Larsen,R. John Aitken,Mark A. Baker,Masahito Ikawa,Reproduction,BIOSCIENTIFICA LTD,Vol. 152,No. 6,p. 665-672,2016年,研究論文(学術雑誌)
  • Lentiviral vector-mediated complementation restored fetal viability but not placental hyperplasia in Plac1-deficient mice,Masanaga Muto,Yoshitaka Fujihara,Tomohiro Tobita,Daiji Kiyozumi,Masahito Ikawa,Biology of Reproduction,SOC STUDY REPRODUCTION,Vol. 94,No. 1,2016年01月01日,研究論文(学術雑誌)
  • A role of TMEM16E carrying a scrambling domain in sperm motility,Sayuri Gyobu,Haruhiko Miyata,Masahito Ikawa,Daiju Yamazaki,Hiroshi Takeshima,Jun Suzuki,Shigekazu Nagata,Molecular and Cellular Biology,AMER SOC MICROBIOLOGY,Vol. 36,No. 4,p. 645-659,2016年,研究論文(学術雑誌)
  • Ground-based assessment of JAXA mouse habitat cage unit by mouse phenotypic studies,Miki Shimbo,Takashi Kudo,Michito Hamada,Hyojung Jeon,Yuki Imamura,Keigo Asano,Risa Okada,Yuki Tsunakawa,Seiya Mizuno,Ken Ichi Yagami,Chihiro Ishikawa,Haiyan Li,Takashi Shiga,Junji Ishida,Juri Hamada,Kazuya Murata,Tomohiro Ishimaru,Misuzu Hashimoto,Akiyoshi Fukamizu,Mutsumi Yamane,Masahito Ikawa,Hironobu Morita,Masahiro Shinohara,Hiroshi Asahara,Taishin Akiyama,Nobuko Akiyama,Hiroki Sasanuma,Nobuaki Yoshida,Rui Zhou,Ying Ying Wang,Taito Ito,Yuko Kokubu,Taka Aki K. Noguchi,Hisako Ishimine,Akira Kurisaki,Dai Shiba,Hiroyasu Mizuno,Masaki Shirakawa,Naoki Ito,Shin’Ichi Takeda,Satoru Takahashi,Experimental Animals,International Press Editing Centre Incorporation,Vol. 65,No. 2,p. 175-187,2016年,研究論文(学術雑誌)
  • A GPI processing phospholipase A2, PGAP6, modulates Nodal signaling in embryos by shedding CRIPTO,Gun Hee Lee,Morihisa Fujita,Katsuyoshi Takaoka,Yoshiko Murakami,Yoshitaka Fujihara,Noriyuki Kanzawa,Kei Ichi Murakami,Eriko Kajikawa,Yoko Takada,Kazunobu Saito,Masahito Ikawa,Hiroshi Hamada,Yusuke Maeda,Taroh Kinoshita,Journal of Cell Biology,Vol. 215,No. 5,p. 705-718,2016年,研究論文(学術雑誌)
  • Elf5-centered transcription factor hub controls trophoblast stem cell self-renewal and differentiation through stoichiometry sensitive shifts in target gene networks,Paulina A. Latos,Arnold R. Sienerth,Alexander Murray,Claire E. Senner,Masanaga Muto,Masahito Ikawa,David Oxley,Sarah Burge,Brian J. Cox,Myriam Hemberger,Genes and Development,COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT,Vol. 29,No. 23,p. 2435-2448,2015年12月01日,研究論文(学術雑誌)
  • CRISPR/Cas9-mediated rapid generation of multiple mouse lines identified Ccdc63 as essential for spermiogenesis,Samantha A.M. Young,Haruhiko Miyata,Yuhkoh Satouh,Hirotaka Kato,Kaori Nozawa,Ayako Isotani,R. John Aitken,Mark A. Baker,Masahito Ikawa,International Journal of Molecular Sciences,MDPI AG,Vol. 16,No. 10,p. 24732-24750,2015年10月16日,研究論文(学術雑誌)
  • Calcitonin Receptor Signaling Inhibits Muscle Stem Cells from Escaping the Quiescent State and the Niche,Masahiko Yamaguchi,Yoko Watanabe,Takuji Ohtani,Akiyoshi Uezumi,Norihisa Mikami,Miki Nakamura,Takahiko Sato,Masahito Ikawa,Mikio Hoshino,Kunihiro Tsuchida,Yuko Miyagoe-Suzuki,Kazutake Tsujikawa,Shin'ichi Takeda,Hiroshi Yamamoto,So ichiro Fukada,Cell Reports,CELL PRESS,Vol. 13,No. 2,p. 302-314,2015年10月13日,研究論文(学術雑誌)
  • Sperm postacrosomal WW domain-binding protein is not required for mouse egg activation,Yuhkoh Satouh,Kaori Nozawa,Masahito Ikawa,Biology of Reproduction,Society for the Study of Reproduction,Vol. 93,No. 4,2015年10月01日,研究論文(学術雑誌)
  • Sperm postacrosomal WW domain-binding protein is not required for mouse egg activation,Yuhkoh Satouh,Kaori Nozawa,Masahito Ikawa,Biology of Reproduction,SOC STUDY REPRODUCTION,Vol. 93,No. 4,2015年10月01日,研究論文(学術雑誌)
  • Calcitonin Receptor Signaling Inhibits Muscle Stem Cells from Escaping the Quiescent State and the Niche,Masahiko Yamaguchi,Yoko Watanabe,Takuji Ohtani,Akiyoshi Uezumi,Norihisa Mikami,Miki Nakamura,Takahiko Sato,Masahito Ikawa,Mikio Hoshino,Kunihiro Tsuchida,Yuko Miyagoe-Suzuki,Kazutake Tsujikawa,Shin'ichi Takeda,Hiroshi Yamamoto,So-ichiro Fukada,CELL REPORTS,CELL PRESS,Vol. 13,No. 2,p. 302-314,2015年10月,研究論文(学術雑誌)
  • Calreticulin is required for development of the cumulus oocyte complex and female fertility,Keizo Tokuhiro,Yuhkoh Satouh,Kaori Nozawa,Ayako Isotani,Yoshitaka Fujihara,Yumiko Hirashima,Hiroyuki Matsumura,Kazuhiro Takumi,Takashi Miyano,Masaru Okabe,Adam M. Benham,Masahito Ikawa,Scientific Reports,NATURE PUBLISHING GROUP,Vol. 5,2015年09月21日,研究論文(学術雑誌)
  • Double strand break repair by capture of retrotransposon sequences and reverse-transcribed spliced mRNA sequences in mouse zygotes,Ryuichi Ono,Masayuki Ishii,Yoshitaka Fujihara,Moe Kitazawa,Takako Usami,Tomoko Kaneko-Ishino,Jun Kanno,Masahito Ikawa,Fumitoshi Ishino,Scientific Reports,NATURE PUBLISHING GROUP,Vol. 5,2015年07月28日,研究論文(学術雑誌)
  • Advantages of using the CRISPR/Cas9 system of genome editing to investigate male reproductive mechanisms using mouse models,Samantha A.M. Young,R. John Aitken,Masahito Ikawa,Asian Journal of Andrology,MEDKNOW PUBLICATIONS & MEDIA PVT LTD,Vol. 17,No. 4,p. 623-627,2015年07月,研究論文(国際会議プロシーディングス)
  • APJ Regulates Parallel Alignment of Arteries and Veins in the Skin,Hiroyasu Kidoya,Hisamichi Naito,Fumitaka Muramatsu,Daishi Yamakawa,Weizhen Jia,Masahito Ikawa,Takashi Sonobe,Hirotsugu Tsuchimochi,Mikiyasu Shirai,Ralf H. Adams,Akiyoshi Fukamizu,Nobuyuki Takakura,Developmental Cell,CELL PRESS,Vol. 33,No. 3,p. 247-259,2015年05月04日,研究論文(学術雑誌)
  • A novel transcriptional factor Nkapl is a germ cell-specific suppressor of Notch signaling and is indispensable for spermatogenesis,Hidenobu Okuda,Hiroshi Kiuchi,Tetsuya Takao,Yasushi Miyagawa,Akira Tsujimura,Norio Nonomura,Haruhiko Miyata,Masaru Okabe,Masahito Ikawa,Yoshitaka Kawakami,Naoki Goshima,Morimasa Wada,Hiromitsu Tanaka,PLoS ONE,PUBLIC LIBRARY SCIENCE,Vol. 10,No. 4,2015年04月,研究論文(学術雑誌)
  • Quantitative assessment of telomerase components in cancer cell lines,Semih Can Akincilar,Kee Chung Low,Chia Yi Liu,Ting Dong Yan,Asami Oji,Masahito Ikawa,Shang Li,Vinay Tergaonkar,FEBS Letters,WILEY-BLACKWELL,Vol. 589,No. 9,p. 974-984,2015年04月,研究論文(学術雑誌)
  • One-step generation of multiple transgenic mouse lines using an improved Pronuclear Injection-based Targeted Transgenesis (i-PITT),Masato Ohtsuka,Hiromi Miura,Keiji Mochida,Michiko Hirose,Ayumi Hasegawa,Atsuo Ogura,Ryuta Mizutani,Minoru Kimura,Ayako Isotani,Masahito Ikawa,Masahiro Sato,Channabasavaiah B. Gurumurthy,BMC GENOMICS,BIOMED CENTRAL LTD,Vol. 16,No. 1,2015年04月,研究論文(学術雑誌)
  • A Novel Transcriptional Factor Nkapl Is a Germ Cell-Specific Suppressor of Notch Signaling and Is Indispensable for Spermatogenesis,Hidenobu Okuda,Hiroshi Kiuchi,Tetsuya Takao,Yasushi Miyagawa,Akira Tsujimura,Norio Nonomura,Haruhiko Miyata,Masaru Okabe,Masahito Ikawa,Yoshitaka Kawakami,Naoki Goshima,Morimasa Wada,Hiromitsu Tanaka,PLOS ONE,PUBLIC LIBRARY SCIENCE,Vol. 10,No. 4,2015年04月,研究論文(学術雑誌)
  • One-step generation of multiple transgenic mouse lines using an improved Pronuclear Injection-based Targeted Transgenesis (i-PITT),Masato Ohtsuka,Hiromi Miura,Keiji Mochida,Michiko Hirose,Ayumi Hasegawa,Atsuo Ogura,Ryuta Mizutani,Minoru Kimura,Ayako Isotani,Masahito Ikawa,Masahiro Sato,Channabasavaiah B. Gurumurthy,BMC Genomics,BIOMED CENTRAL LTD,Vol. 16,No. 1,2015年04月,研究論文(学術雑誌)
  • Genome editing in mice using crispr/cas,A. M.Samantha Young,Mark Baker,Masahito Ikawa,Targeted Genome Editing Using Site-Specific Nucleases: ZFNs, TALENs, and the CRISPR/Cas9 System,Springer Japan,p. 151-166,2015年01月01日,論文集(書籍)内論文
  • Pluripotent stem cells derived from mouse primordial germ cells by small molecule compounds,Tohru Kimura,Yoshiaki Kaga,Yoichi Sekita,Keita Fujikawa,Tsunetoshi Nakatani,Mika Odamoto,Soichiro Funaki,Masahito Ikawa,Kuniya Abe,Toru Nakano,Stem Cells,WILEY-BLACKWELL,Vol. 33,No. 1,p. 45-55,2015年01月01日,研究論文(学術雑誌)
  • Single-step generation of rabbits carrying a targeted allele of the tyrosinase gene using CRISPR/Cas9,Arata Honda,Michiko Hirose,Tadashi Sankai,Lubna Yasmin,Kazuaki Yuzawa,Kimiko Honsho,Haruna Izu,Atsushi Iguchi,Masahito Ikawa,Atsuo Ogura,Experimental Animals,INT PRESS EDITING CENTRE INC,Vol. 64,No. 1,p. 31-37,2015年,研究論文(学術雑誌)
  • Concurrent production of multiple targeted transgenic mouse lines with C57BL/6N genetic background by improved PITT,Masato Ohtsuka,Hiromi Miura,Minoru Kimura,Ayako Isotani,Masahito Ikawa,Masahiro Sato,Channabasavaiah Gurumurthy,TRANSGENIC RESEARCH,SPRINGER,Vol. 23,No. 5,p. 855-856,2014年10月
  • Simple generation of albino C57BL/6J mice with G291T mutation in the tyrosinase gene by the CRISPR/Cas9 system,Seiya Mizuno,Tra Thi Huong Dinh,Kanako Kato,Saori Mizuno-Iijima,Yoko Tanimoto,Yoko Daitoku,Yoshikazu Hoshino,Masahito Ikawa,Satoru Takahashi,Fumihiro Sugiyama,Ken Ichi Yagami,Mammalian Genome,SPRINGER,Vol. 25,No. 7-8,p. 327-334,2014年08月,研究論文(学術雑誌)
  • Deletion of N-myc downstream-regulated gene 2 attenuates reactive astrogliosis and inflammatory response in a mouse model of cortical stab injury,Mika Takarada-Iemata,Dai Kezuka,Toshiaki Takeichi,Masahito Ikawa,Tsuyoshi Hattori,Yasuko Kitao,Osamu Hori,Journal of Neurochemistry,WILEY-BLACKWELL,Vol. 130,No. 3,p. 374-387,2014年08月,研究論文(学術雑誌)
  • NUCKS Is a Positive Transcriptional Regulator of Insulin Signaling,Beiying Qiu,Xiaohe Shi,Ee Tsin Wong,Joy Lim,Marco Bezzi,Diana Low,Qiling Zhou,Semih Can Akincilar,Manikandan Lakshmanan,Hannah L.F. Swa,Jill Mae Lan Tham,Jayantha Gunaratne,Kenneth K.Y. Cheng,Wanjin Hong,Karen S.L. Lam,Masahito Ikawa,Ernesto Guccione,Aimin Xu,Weiping Han,Vinay Tergaonkar,Cell Reports,CELL PRESS,Vol. 7,No. 6,p. 1876-1886,2014年06月26日,研究論文(学術雑誌)
  • GPI-anchored protein complex, LY6K/TEX101, is required for sperm migration into the oviduct and male fertility in mice1,Yoshitaka Fujihara,Masaru Okabe,Masahito Ikawa,Biology of Reproduction,SOC STUDY REPRODUCTION,Vol. 90,No. 3,2014年03月,研究論文(学術雑誌)
  • Liver-Specific γ-Glutamyl Carboxylase-Deficient Mice Display Bleeding Diathesis and Short Life Span.,Azuma K,Tsukui T,Ikeda K,Shiba S,Nakagawa K,Okano T,Urano T,Horie-Inoue K,Ouchi Y,Ikawa M,Inoue S,PLoS One.,PUBLIC LIBRARY SCIENCE,Vol. 9,No. 2,2014年02月10日,研究論文(学術雑誌)
  • Effect of isolated AMP deaminase deficiency on skeletal muscle function,Jidong Cheng,Hiroko Morisaki,Naomi Sugimoto,Atsushi Dohi,Takuya Shintani,Erika Kimura,Keiko Toyama,Masahito Ikawa,Masaru Okabe,Itsuro Higuchi,Satoshi Matsuo,Yasuaki Kawai,Ichiro Hisatome,Takako Sugama,Edward W. Holmes,Takayuki Morisaki,Molecular Genetics and Metabolism Reports,Elsevier Inc.,Vol. 1,No. 1,p. 51-59,2014年,研究論文(学術雑誌)
  • CRISPR/Cas9-based genome editing in mice by single plasmid injection,Yoshitaka Fujihara,Masahito Ikawa,Methods in Enzymology,ELSEVIER ACADEMIC PRESS INC,Vol. 546,No. C,p. 319-336,2014年,論文集(書籍)内論文
  • RHOF promotes murine marginal zone B cell development,Mayuko Kishimoto,Takenori Matsuda,Shougo Yanase,Akira Katsumi,Nobuaki Suzuki,Makoto Ikejiri,Akira Takagi,Masahito Ikawa,Tetsuhito Kojima,Shinji Kunishima,Hitoshi Kiyoi,Tomoki Naoe,Tadashi Matsushita,Mitsuo Maruyama,Nagoya Journal of Medical Science,Vol. 76,No. 3-4,p. 293-305,2014年,研究論文(学術雑誌)
  • Effect of isolated AMP deaminase deficiency on skeletal muscle function,Jidong Cheng,Hiroko Morisaki,Naomi Sugimoto,Atsushi Dohi,Takuya Shintani,Erika Kimura,Keiko Toyama,Masahito Ikawa,Masaru Okabe,Itsuro Higuchi,Satoshi Matsuo,Yasuaki Kawai,Ichiro Hisatome,Takako Sugama,Edward W. Holmes,Takayuki Morisaki,Molecular Genetics and Metabolism Reports,Elsevier Inc.,Vol. 1,No. 1,p. 51-59,2014年,研究論文(学術雑誌)
  • CRISPR/Cas9-based genome editing in mice by single plasmid injection,Yoshitaka Fujihara,Masahito Ikawa,Methods in Enzymology,Academic Press Inc.,Vol. 546,No. C,p. 319-336,2014年,研究論文(学術雑誌)
  • Effect of isolated AMP deaminase deficiency on skeletal muscle function,Jidong Cheng,Hiroko Morisaki,Naomi Sugimoto,Atsushi Dohi,Takuya Shintani,Erika Kimura,Keiko Toyama,Masahito Ikawa,Masaru Okabe,Itsuro Higuchi,Satoshi Matsuo,Yasuaki Kawai,Ichiro Hisatome,Takako Sugama,Edward W. Holmes,Takayuki Morisaki,Molecular Genetics and Metabolism Reports,Elsevier Inc.,Vol. 1,No. 1,p. 51-59,2014年,研究論文(学術雑誌)
  • GPI-anchored protein complex, LY6K/TEX101, is required for sperm migration into the oviduct and male fertility in mice1,Yoshitaka Fujihara,Masaru Okabe,Masahito Ikawa,Biology of Reproduction,Society for the Study of Reproduction,Vol. 90,No. 3,2014年,研究論文(学術雑誌)
  • Feasibility for a large scale mouse mutagenesis by injecting CRISPR/Cas plasmid into zygotes,Daisuke Mashiko,Samantha A.M. Young,Masanaga Muto,Hirotaka Kato,Kaori Nozawa,Masaki Ogawa,Taichi Noda,Yeon Joo Kim,Yuhkoh Satouh,Yoshitaka Fujihara,Masahito Ikawa,Development Growth and Differentiation,WILEY-BLACKWELL,Vol. 56,No. 1,p. 122-129,2014年01月,研究論文(学術雑誌)
  • Generation of mutant mice by pronuclear injection of circular plasmid expressing Cas9 and single guided RNA,Daisuke Mashiko,Yoshitaka Fujihara,Yuhkoh Satouh,Haruhiko Miyata,Ayako Isotani,Masahito Ikawa,Scientific Reports,NATURE PUBLISHING GROUP,Vol. 3,2013年11月27日,研究論文(学術雑誌)
  • Targeted disruption of fad24, a regulator of adipogenesis, causes pre-implantation embryonic lethality due to the growth defect at the blastocyst stage,Natsuki Ochiai,Makoto Nishizuka,Tomomi Miyamoto,Ichiro Miyoshi,Masahito Ikawa,Shigehiro Osada,Masayoshi Imagawa,Biochemical and Biophysical Research Communications,Vol. 438,No. 2,p. 301-305,2013年08月23日,研究論文(学術雑誌)
  • Establishment of Mouse Model of MYH9 Disorders: Heterozygous R702C Mutation Provokes Macrothrombocytopenia with Leukocyte Inclusion Bodies, Renal Glomerulosclerosis and Hearing Disability,Nobuaki Suzuki,Shinji Kunishima,Makoto Ikejiri,Shoichi Maruyama,Michihiko Sone,Akira Takagi,Masahito Ikawa,Masaru Okabe,Tetsuhito Kojima,Hidehiko Saito,Tomoki Naoe,Tadashi Matsushita,PLoS ONE,Vol. 8,No. 8,2013年08月20日,研究論文(学術雑誌)
  • Macrophage MHC and T-Cell receptors essential for rejection of allografted skin and lymphoma,Junko Tashiro-Yamaji,Shogo Maeda,Masahito Ikawa,Masaru Okabe,Takahiro Kubota,Ryotaro Yoshida,Transplantation,Vol. 96,No. 3,p. 251-257,2013年08月15日,研究論文(学術雑誌)
  • Molecular dissection of IZUMO1, a sperm protein essential for sperm-egg fusion,Naokazu Inoue,Daizo Hamada,Hironari Kamikubo,Kunio Hirata,Mikio Kataoka,Masaki Yamamoto,Masahito Ikawa,Masaru Okabe,Yoshihisa Hagihara,Development (Cambridge),COMPANY OF BIOLOGISTS LTD,Vol. 140,No. 15,p. 3221-3229,2013年08月01日,研究論文(学術雑誌)
  • Recruitment of cyclin G2 to promyelocytic leukemia nuclear bodies promotes dephosphorylation of γH2AX following treatment with ionizing radiation.,Naito Y,Yabuta N,Sato J,Ohno S,Sakata M,Kasama T,Ikawa M,Nojima H,Cell cycle (Georgetown, Tex.),Taylor and Francis Inc.,Vol. 12,No. 11,p. 1773-1784,2013年06月01日,研究論文(学術雑誌)
  • Expression of TEX101, regulated by ACE, is essential for the production of fertile mouse spermatozoa,Yoshitaka Fujihara,Keizo Tokuhiro,Yuko Muro,Gen Kondoh,Yoshihiko Araki,Masahito Ikawa,Masaru Okabe,Proceedings of the National Academy of Sciences of the United States of America,NATL ACAD SCIENCES,Vol. 110,No. 20,p. 8111-8116,2013年05月14日,研究論文(学術雑誌)
  • Functional and structural study of mouse sperm protein, IZUMO1, by using molecular dissection,Naokazu Inoue,Daizo Hamada,Hironari Kamikubo,Kunio Hirata,Mikio Kataoka,Masaki Yamamoto,Masahito Ikawa,Masaru Okabe,Yoshihisa Hagihara,Development,Vol. 140,No. 15,p. 3221-3229,2013年,研究論文(その他学術会議資料等)
  • Production of mouse pups from germline transmission-failed knockout chimeras,Yoshitaka Fujihara,Kazuhiro Kaseda,Naokazu Inoue,Masahito Ikawa,Masaru Okabe,Transgenic Research,Vol. 22,No. 1,p. 195-200,2013年,研究論文(学術雑誌)
  • Neutrophil infiltration during inflammation is regulated by PILRα via modulation of integrin activation.,Wang J,Shiratori I,Uehori J,Ikawa M,Arase H,Nature immunology,Vol. 14,No. 1,p. 34-40,2013年01月,研究論文(学術雑誌)
  • N-terminal truncation of Lats1 causes abnormal cell growth control and chromosomal instability,Norikazu Yabuta,Satomi Mukai,Ayumi Okamoto,Daisuke Okuzaki,Hirokazu Suzuki,Kosuke Torigata,Kaori Yoshida,Nobuhiro Okada,Daisaku Miura,Akihiko Ito,Masahito Ikawa,Masaru Okabe,Hiroshi Nojima,Journal of Cell Science,COMPANY OF BIOLOGISTS LTD,Vol. 126,No. 2,p. 508-519,2013年01月,研究論文(学術雑誌)
  • A point mutation in Semaphorin 4A associates with defective endosomal sorting and causes retinal degeneration,Satoshi Nojima,Toshihiko Toyofuku,Hiroyuki Kamao,Chie Ishigami,Jun Kaneko,Tatsusada Okuno,Hyota Takamatsu,Daisuke Ito,Sujin Kang,Tetsuya Kimura,Yuji Yoshida,Keiko Morimoto,Yohei Maeda,Atsushi Ogata,Masahito Ikawa,Eiichi Morii,Katsuyuki Aozasa,Junichi Takagi,Masayo Takahashi,Atsushi Kumanogoh,Nature Communications,NATURE PUBLISHING GROUP,Vol. 4,2013年,研究論文(学術雑誌)
  • Mice deficient in ficolin, a lectin complement pathway recognition molecule, are susceptible to Streptococcus pneumoniae infection,Yuichi Endo,Minoru Takahashi,Daisuke Iwaki,Yumi Ishida,Naomi Nakazawa,Toshihisa Kodama,Tomohiro Matsuzaka,Kazuko Kanno,Yu Liu,Kohsuke Tsuchiya,Ikuo Kawamura,Masahito Ikawa,Satoshi Waguri,Ikuo Wada,Misao Matsushita,Wilhelm J. Schwaeble,Teizo Fujita,Journal of Immunology,AMER ASSOC IMMUNOLOGISTS,Vol. 189,No. 12,p. 5860-5866,2012年12月15日,研究論文(学術雑誌)
  • AMPD3-deficient mice exhibit increased erythrocyte ATP levels but anemia not improved due to PK deficiency,Jidong Cheng,Hiroko Morisaki,Keiko Toyama,Masahito Ikawa,Masaru Okabe,Takayuki Morisaki,Genes to Cells,WILEY-BLACKWELL,Vol. 17,No. 11,p. 913-922,2012年11月,研究論文(学術雑誌)
  • SPACA1-deficient male mice are infertile with abnormally shaped sperm heads reminiscent of globozoospermia,Yoshitaka Fujihara,Yuhkoh Satouh,Naokazu Inoue,Ayako Isotani,Masahito Ikawa,Masaru Okabe,Development (Cambridge),COMPANY OF BIOLOGISTS LTD,Vol. 139,No. 19,p. 3583-3589,2012年10月01日,研究論文(学術雑誌)
  • Tetraspanin-interacting protein IGSF8 is dispensable for mouse fertility,Naokazu Inoue,Takao Nishikawa,Masahito Ikawa,Masaru Okabe,Fertility and Sterility,ELSEVIER SCIENCE INC,Vol. 98,No. 2,p. 465-470,2012年08月,研究論文(学術雑誌)
  • GPHR-dependent functions of the golgi apparatus are essential for the formation of lamellar granules and the skin barrier,Masahito Tarutani,Kimiko Nakajima,Yoshikazu Uchida,Mikiro Takaishi,Naoko Goto-Inoue,Masahito Ikawa,Mitsutoshi Setou,Taroh Kinoshita,Peter M. Elias,Shigetoshi Sano,Yusuke Maeda,Journal of Investigative Dermatology,NATURE PUBLISHING GROUP,Vol. 132,No. 8,p. 2019-2025,2012年08月,研究論文(学術雑誌)
  • Mice expressing aberrant sperm-specific protein PMIS2 produce normal-looking but fertilization-incompetent spermatozoa,Ryo Yamaguchi,Yoshitaka Fujiharaa,Masahito Ikawa,Masaru Okabe,Molecular Biology of the Cell,AMER SOC CELL BIOLOGY,Vol. 23,No. 14,p. 2671-2679,2012年07月15日,研究論文(学術雑誌)
  • Cold-inducible RNA-binding protein (Cirp) interacts with Dyrk1b/Mirk and promotes proliferation of immature male germ cells in mice,Tomoko Masuda,Katsuhiko Itoh,Hiroaki Higashitsuji,Hisako Higashitsuji,Noa Nakazawa,Toshiharu Sakurai,Yu Liu,Hiromu Tokuchi,Takanori Fujita,Yan Zhao,Hiroyuki Nishiyama,Takashi Tanaka,Manabu Fukumoto,Masahito Ikawa,Masaru Okabe,Jun Fujita,Proceedings of the National Academy of Sciences of the United States of America,NATL ACAD SCIENCES,Vol. 109,No. 27,p. 10885-10890,2012年07月03日,研究論文(学術雑誌)
  • Erratum: Protein disulfide isomerase homolog PDILT is required for quality control of sperm membrane protein ADAM3 and male infertility (Proceedings of the National Academy of Sciences of the United States of America (2012) 109, 10 (3850-3855) DOI: 10.1073/pnas.1117963109),Keizo Tokuhiro,Masahito Ikawa,Adam M. Benham,Masaru Okabe,Proceedings of the National Academy of Sciences of the United States of America,Vol. 109,No. 15,2012年04月,研究論文(学術雑誌)
  • Characterization of inclusion bodies with cytoprotective properties formed by seipinopathy-linked mutant seipin,Daisuke Ito,Takuya Yagi,Masahito Ikawa,Norihiro Suzuki,Human Molecular Genetics,OXFORD UNIV PRESS,Vol. 21,No. 3,p. 635-646,2012年02月,研究論文(学術雑誌)
  • Visualization of the moment of mouse sperm-egg fusion and dynamic localization of IZUMO1,Yuhkoh Satouh,Naokazu Inoue,Masahito Ikawa,Masaru Okabe,Journal of Cell Science,COMPANY OF BIOLOGISTS LTD,Vol. 125,No. 21,p. 4985-4990,2012年,研究論文(学術雑誌)
  • Proteinuria in AMPD2-deficient mice,Keiko Toyama,Hiroko Morisaki,Jidong Cheng,Hiroshi Kawachi,Fujio Shimizu,Masahito Ikawa,Masaru Okabe,Takayuki Morisaki,Genes to Cells,WILEY-BLACKWELL,Vol. 17,No. 1,p. 28-38,2012年01月,研究論文(学術雑誌)
  • Acrosome-reacted mouse spermatozoa recovered from the perivitelline space can fertilize other eggs,Naokazu Inoue,Yuhkoh Satouh,Masahito Ikawa,Masaru Okabe,Ryuzo Yanagimachi,Proceedings of the National Academy of Sciences of the United States of America,NATL ACAD SCIENCES,Vol. 108,No. 50,p. 20008-20011,2011年12月13日,研究論文(学術雑誌)
  • Acrosome-reacted mouse spermatozoa recovered from the perivitelline space can fertilize other eggs,Naokazu Inoue,Yuhkoh Satouh,Masahito Ikawa,Masaru Okabe,Ryuzo Yanagimachi,PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,NATL ACAD SCIENCES,Vol. 108,No. 50,p. 20008-20011,2011年12月,研究論文(学術雑誌)
  • Acrosome-reacted mouse spermatozoa recovered from the perivitelline space can fertilize other eggs,Naokazu Inoue,Yuhkoh Satouh,Masahito Ikawa,Masaru Okabe,Ryuzo Yanagimachi,PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,NATL ACAD SCIENCES,Vol. 108,No. 50,p. 20008-20011,2011年12月,研究論文(学術雑誌)
  • Dynamic modification of sphingomyelin in lipid microdomains controls development of obesity, fatty liver, and type 2 diabetes,Susumu Mitsutake,Kota Zama,Hazuki Yokota,Tetsuya Yoshida,Miki Tanaka,Masaru Mitsui,Masahito Ikawa,Masaru Okabe,Yoshikazu Tanaka,Tadashi Yamashita,Hiroshi Takemoto,Toshiro Okazaki,Ken Watanabe,Yasuyuki Igarashi,Journal of Biological Chemistry,AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC,Vol. 286,No. 32,p. 28544-28555,2011年08月12日,研究論文(学術雑誌)
  • Factor for Adipocyte Differentiation 158 Gene Disruption Prevents the Body Weight Gain and Insulin Resistance Induced by a High-Fat Diet,Takahiro Hayashi,Yuriko Nozaki,Makoto Nishizuka,Masahito Ikawa,Shigehiro Osada,Masayoshi Imagawa,BIOLOGICAL & PHARMACEUTICAL BULLETIN,PHARMACEUTICAL SOC JAPAN,Vol. 34,No. 8,p. 1257-1263,2011年08月,研究論文(学術雑誌)
  • Factor for Adipocyte Differentiation 158 gene disruption prevents the body weight gain and insulin resistance induced by a high-fat diet,Takahiro Hayashi,Yuriko Nozaki,Makoto Nishizuka,Masahito Ikawa,Shigehiro Osada,Masayoshi Imagawa,Biological and Pharmaceutical Bulletin,PHARMACEUTICAL SOC JAPAN,Vol. 34,No. 8,p. 1257-1263,2011年08月,研究論文(学術雑誌)
  • Dynamic Modification of Sphingomyelin in Lipid Microdomains Controls Development of Obesity, Fatty Liver, and Type 2 Diabetes,Susumu Mitsutake,Kota Zama,Hazuki Yokota,Tetsuya Yoshida,Miki Tanaka,Masaru Mitsui,Masahito Ikawa,Masaru Okabe,Yoshikazu Tanaka,Tadashi Yamashita,Hiroshi Takemoto,Toshiro Okazaki,Ken Watanabe,Yasuyuki Igarashi,JOURNAL OF BIOLOGICAL CHEMISTRY,AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC,Vol. 286,No. 32,p. 28544-28555,2011年08月,研究論文(学術雑誌)
  • Factor for Adipocyte Differentiation 158 Gene Disruption Prevents the Body Weight Gain and Insulin Resistance Induced by a High-Fat Diet,Takahiro Hayashi,Yuriko Nozaki,Makoto Nishizuka,Masahito Ikawa,Shigehiro Osada,Masayoshi Imagawa,BIOLOGICAL & PHARMACEUTICAL BULLETIN,PHARMACEUTICAL SOC JAPAN,Vol. 34,No. 8,p. 1257-1263,2011年08月,研究論文(学術雑誌)
  • Dynamic Modification of Sphingomyelin in Lipid Microdomains Controls Development of Obesity, Fatty Liver, and Type 2 Diabetes,Susumu Mitsutake,Kota Zama,Hazuki Yokota,Tetsuya Yoshida,Miki Tanaka,Masaru Mitsui,Masahito Ikawa,Masaru Okabe,Yoshikazu Tanaka,Tadashi Yamashita,Hiroshi Takemoto,Toshiro Okazaki,Ken Watanabe,Yasuyuki Igarashi,JOURNAL OF BIOLOGICAL CHEMISTRY,AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC,Vol. 286,No. 32,p. 28544-28555,2011年08月,研究論文(学術雑誌)
  • Homologous Recombination in Rat Germline Stem Cells,Mito Kanatsu-Shinohara,Megumi Kato-Itoh,Masahito Ikawa,Masanori Takehashi,Makoto Sanbo,Yuka Morioka,Takashi Tanaka,Hiroko Morimoto,Masumi Hirabayashi,Takashi Shinohara,BIOLOGY OF REPRODUCTION,SOC STUDY REPRODUCTION,Vol. 85,No. 1,p. 208-217,2011年07月,研究論文(学術雑誌)
  • Homologous recombination in rat germline stem cells,Mito Kanatsu-Shinohara,Megumi Kato-Itoh,Masahito Ikawa,Masanori Takehashi,Makoto Sanbo,Yuka Morioka,Takashi Tanaka,Hiroko Morimoto,Masumi Hirabayashi,Takashi Shinohara,Biology of Reproduction,SOC STUDY REPRODUCTION,Vol. 85,No. 1,p. 208-217,2011年07月01日,研究論文(学術雑誌)
  • Homologous Recombination in Rat Germline Stem Cells,Mito Kanatsu-Shinohara,Megumi Kato-Itoh,Masahito Ikawa,Masanori Takehashi,Makoto Sanbo,Yuka Morioka,Takashi Tanaka,Hiroko Morimoto,Masumi Hirabayashi,Takashi Shinohara,BIOLOGY OF REPRODUCTION,SOC STUDY REPRODUCTION,Vol. 85,No. 1,p. 208-217,2011年07月,研究論文(学術雑誌)
  • Targeted disruption of one of the importin α family members leads to female functional incompetence in delivery.,Moriyama T,Nagai M,Oka M,Ikawa M,Okabe M,Yoneda Y,FEBS J.,WILEY-BLACKWELL,Vol. 278,No. 9,p. 1561-1572,2011年05月,研究論文(学術雑誌)
  • Targeted disruption of one of the importin alpha family members leads to female functional incompetence in delivery,Tetsuji Moriyama,Masahiro Nagai,Masahiro Oka,Masahito Ikawa,Masaru Okabe,Yoshihiro Yoneda,FEBS JOURNAL,WILEY-BLACKWELL,Vol. 278,No. 9,p. 1561-1572,2011年05月,研究論文(学術雑誌)
  • Targeted disruption of one of the importin α family members leads to female functional incompetence in delivery.,Moriyama T,Nagai M,Oka M,Ikawa M,Okabe M,Yoneda Y,FEBS J.,2011年05月,研究論文(学術雑誌)
  • Formation of a thymus from rat ES cells in xenogeneic nude mouse &lt;-&gt; rat ES chimeras,Ayako Isotani,Hide Hatayama,Kazuhiro Kaseda,Masahito Ikawa,Masaru Okabe,GENES TO CELLS,WILEY-BLACKWELL,Vol. 16,No. 4,p. 397-405,2011年04月,研究論文(学術雑誌)
  • Formation of a thymus from rat ES cells in xenogeneic nude mouse &lt;-&gt; rat ES chimeras,Ayako Isotani,Hide Hatayama,Kazuhiro Kaseda,Masahito Ikawa,Masaru Okabe,GENES TO CELLS,WILEY-BLACKWELL,Vol. 16,No. 4,p. 397-405,2011年04月,研究論文(学術雑誌)
  • Formation of a thymus from rat ES cells in xenogeneic nude mouse↔rat ES chimeras,Ayako Isotani,Hide Hatayama,Kazuhiro Kaseda,Masahito Ikawa,Masaru Okabe,Genes to Cells,WILEY-BLACKWELL,Vol. 16,No. 4,p. 397-405,2011年04月,研究論文(学術雑誌)
  • Mice lacking Ran binding protein 1 are viable and show male infertility,Masahiro Nagai,Tetsuji Moriyama,Rashid Mehmood,Keizo Tokuhiro,Masahito Ikawa,Masaru Okabe,Hiromitsu Tanaka,Yoshihiro Yoneda,FEBS Letters,ELSEVIER SCIENCE BV,Vol. 585,No. 5,p. 791-796,2011年03月09日,研究論文(学術雑誌)
  • Muscle Fiber Type-Predominant Promoter Activity in Lentiviral-Mediated Transgenic Mouse,Tomohiro Suga,En Kimura,Yuka Morioka,Masahito Ikawa,Sheng Li,Katsuhisa Uchino,Yuji Uchida,Satoshi Yamashita,Yasushi Maeda,Jeffrey S. Chamberlain,Makoto Uchino,PLOS ONE,PUBLIC LIBRARY SCIENCE,Vol. 6,No. 3,2011年03月,研究論文(学術雑誌)
  • Mice lacking Ran binding protein 1 are viable and show male infertility,Masahiro Nagai,Tetsuji Moriyama,Rashid Mehmood,Keizo Tokuhiro,Masahito Ikawa,Masaru Okabe,Hiromitsu Tanaka,Yoshihiro Yoneda,FEBS LETTERS,ELSEVIER SCIENCE BV,Vol. 585,No. 5,p. 791-796,2011年03月,研究論文(学術雑誌)
  • Mice lacking Ran binding protein 1 are viable and show male infertility,Masahiro Nagai,Tetsuji Moriyama,Rashid Mehmood,Keizo Tokuhiro,Masahito Ikawa,Masaru Okabe,Hiromitsu Tanaka,Yoshihiro Yoneda,FEBS LETTERS,ELSEVIER SCIENCE BV,Vol. 585,No. 5,p. 791-796,2011年03月,研究論文(学術雑誌)
  • Identification of Semaphorin 4B as a Negative Regulator of Basophil-Mediated Immune Responses,Yukinobu Nakagawa,Hyota Takamatsu,Tatsusada Okuno,Sujin Kang,Satoshi Nojima,Tetsuya Kimura,Tatsuki R. Kataoka,Masahito Ikawa,Toshihiko Toyofuku,Ichiro Katayama,Atsushi Kumanogoh,JOURNAL OF IMMUNOLOGY,AMER ASSOC IMMUNOLOGISTS,Vol. 186,No. 5,p. 2881-2888,2011年03月,研究論文(学術雑誌)
  • Identification of semaphorin 4B as a negative regulator of basophil-mediated immune responses,Yukinobu Nakagawa,Hyota Takamatsu,Tatsusada Okuno,Sujin Kang,Satoshi Nojima,Tetsuya Kimura,Tatsuki R. Kataoka,Masahito Ikawa,Toshihiko Toyofuku,Ichiro Katayama,Atsushi Kumanogoh,Journal of Immunology,AMER ASSOC IMMUNOLOGISTS,Vol. 186,No. 5,p. 2881-2888,2011年03月01日,研究論文(学術雑誌)
  • Muscle Fiber Type-Predominant Promoter Activity in Lentiviral-Mediated Transgenic Mouse,Tomohiro Suga,En Kimura,Yuka Morioka,Masahito Ikawa,Sheng Li,Katsuhisa Uchino,Yuji Uchida,Satoshi Yamashita,Yasushi Maeda,Jeffrey S. Chamberlain,Makoto Uchino,PLOS ONE,PUBLIC LIBRARY SCIENCE,Vol. 6,No. 3,2011年03月,研究論文(学術雑誌)
  • Identification of Semaphorin 4B as a Negative Regulator of Basophil-Mediated Immune Responses,Yukinobu Nakagawa,Hyota Takamatsu,Tatsusada Okuno,Sujin Kang,Satoshi Nojima,Tetsuya Kimura,Tatsuki R. Kataoka,Masahito Ikawa,Toshihiko Toyofuku,Ichiro Katayama,Atsushi Kumanogoh,JOURNAL OF IMMUNOLOGY,AMER ASSOC IMMUNOLOGISTS,Vol. 186,No. 5,p. 2881-2888,2011年03月,研究論文(学術雑誌)
  • Calsperin is a testis-specific chaperone required for sperm fertility,Masahito Ikawa,Keizo Tokuhiro,Ryo Yamaguchi,Adam M. Benham,Taku Tamura,Ikuo Wada,Yuhkoh Satouh,Naokazu Inoue,Masaru Okabe,Journal of Biological Chemistry,AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC,Vol. 286,No. 7,p. 5639-5646,2011年02月18日,研究論文(学術雑誌)
  • Mitochondrial dysfunction and increased reactive oxygen species impair insulin secretion in sphingomyelin synthase 1-null Mice,Masato Yano,Ken Watanabe,Tadashi Yamamoto,Kazutaka Ikeda,Takafumi Senokuchi,Meihong Lu,Tsuyoshi Kadomatsu,Hiroto Tsukano,Masahito Ikawa,Masaru Okabe,Shohei Yamaoka,Toshiro Okazaki,Hisanori Umehara,Tomomi Gotoh,Wen Jie Song,Koichi Node,Ryo Taguchi,Kazuya Yamagata,Yuichi Oike,Journal of Biological Chemistry,AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC,Vol. 286,No. 5,p. 3992-4002,2011年02月04日,研究論文(学術雑誌)
  • Mitochondrial Dysfunction and Increased Reactive Oxygen Species Impair Insulin Secretion in Sphingomyelin Synthase 1-null Mice,Masato Yano,Ken Watanabe,Tadashi Yamamoto,Kazutaka Ikeda,Takafumi Senokuchi,Meihong Lu,Tsuyoshi Kadomatsu,Hiroto Tsukano,Masahito Ikawa,Masaru Okabe,Shohei Yamaoka,Toshiro Okazaki,Hisanori Umehara,Tomomi Gotoh,Wen-Jie Song,Koichi Node,Ryo Taguchi,Kazuya Yamagata,Yuichi Oike,JOURNAL OF BIOLOGICAL CHEMISTRY,AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC,Vol. 286,No. 5,p. 3992-4002,2011年02月,研究論文(学術雑誌)
  • Mitochondrial Dysfunction and Increased Reactive Oxygen Species Impair Insulin Secretion in Sphingomyelin Synthase 1-null Mice,Masato Yano,Ken Watanabe,Tadashi Yamamoto,Kazutaka Ikeda,Takafumi Senokuchi,Meihong Lu,Tsuyoshi Kadomatsu,Hiroto Tsukano,Masahito Ikawa,Masaru Okabe,Shohei Yamaoka,Toshiro Okazaki,Hisanori Umehara,Tomomi Gotoh,Wen-Jie Song,Koichi Node,Ryo Taguchi,Kazuya Yamagata,Yuichi Oike,JOURNAL OF BIOLOGICAL CHEMISTRY,AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC,Vol. 286,No. 5,p. 3992-4002,2011年02月,研究論文(学術雑誌)
  • Calsperin Is a Testis-specific Chaperone Required for Sperm Fertility,Masahito Ikawa,Keizo Tokuhiro,Ryo Yamaguchi,Adam M. Benham,Taku Tamura,Ikuo Wada,Yuhkoh Satouh,Naokazu Inoue,Masaru Okabe,JOURNAL OF BIOLOGICAL CHEMISTRY,AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC,Vol. 286,No. 7,p. 5639-5646,2011年02月,研究論文(学術雑誌)
  • Calsperin Is a Testis-specific Chaperone Required for Sperm Fertility,Masahito Ikawa,Keizo Tokuhiro,Ryo Yamaguchi,Adam M. Benham,Taku Tamura,Ikuo Wada,Yuhkoh Satouh,Naokazu Inoue,Masaru Okabe,JOURNAL OF BIOLOGICAL CHEMISTRY,AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC,Vol. 286,No. 7,p. 5639-5646,2011年02月,研究論文(学術雑誌)
  • Primary screening of single nucleotide polymorphisms in human Calreticulin 3 (CALR3),Shinji Irie,Junko Nakamura,Yasushi Miyagawa,Akira Tsujimura,Hidenobu Okuda,Keisuke Yamamoto,Shinichiro Fukuhara,Iwao Yoshioka,Kiuchi Hiroshi,Yasuhiro Matsuoka,Tetsuya Takao,Norio Nonomura,Masahito Ikawa,Keizo Tokuhiro,Masaru Okabe,Tomomi Shibata,Kyoko Fujimoto,Morimasa Wada,Hiromitsu Tanaka,Open Andrology Journal,Vol. 3,p. 30-35,2011年,研究論文(学術雑誌)
  • The mechanism of sperm-egg interaction and the involvement of IZUMO1 in fusion,Naokazu Inoue,Masahito Ikawa,Masaru Okabe,Asian Journal of Andrology,ACTA PHARMACOLOGICA SINICA,Vol. 13,No. 1,p. 81-87,2011年01月
  • The mechanism of sperm-egg interaction and the involvement of IZUMO1 in fusion,Naokazu Inoue,Masahito Ikawa,Masaru Okabe,ASIAN JOURNAL OF ANDROLOGY,ACTA PHARMACOLOGICA SINICA,Vol. 13,No. 1,p. 81-87,2011年01月
  • Muscle fiber type-predominant promoter activity in lentiviral-mediated transgenic mouse,Tomohiro Suga,En Kimura,Yuka Morioka,Masahito Ikawa,Sheng Li,Katsuhisa Uchino,Yuji Uchida,Satoshi Yamashita,Yasushi Maeda,Jeffrey S. Chamberlain,Makoto Uchino,PLoS ONE,PUBLIC LIBRARY SCIENCE,Vol. 6,No. 3,2011年,研究論文(学術雑誌)
  • The mechanism of sperm-egg interaction and the involvement of IZUMO1 in fusion,Naokazu Inoue,Masahito Ikawa,Masaru Okabe,ASIAN JOURNAL OF ANDROLOGY,ACTA PHARMACOLOGICA SINICA,Vol. 13,No. 1,p. 81-87,2011年01月
  • Calponin 3 regulates actin cytoskeleton rearrangement in trophoblastic cell fusion,Yukinao Shibukawa,Natsuko Yamazaki,Keiichi Kumasawa,Etsuko Daimon,Michiko Tajiri,Yuka Okada,Masahito Ikawa,Yoshinao Wada,Molecular Biology of the Cell,AMER SOC CELL BIOLOGY,Vol. 21,No. 22,p. 3973-3984,2010年11月15日,研究論文(学術雑誌)
  • Establishment and analysis of SLC22A12 (URAT1) knockout mouse,M. Hosoyamada,Y. Takiue,H. Morisaki,J. Cheng,M. Ikawa,M. Okabe,T. Morisaki,K. Ichida,T. Hosoya,T. Shibasaki,Nucleosides, Nucleotides and Nucleic Acids,TAYLOR & FRANCIS INC,Vol. 29,No. 4-6,p. 314-320,2010年06月,研究論文(学術雑誌)
  • Sperm equatorial segment protein 1, SPESP1, is required for fully fertile sperm in mouse,Yoshitaka Fujihara,Masao Murakami,Naokazu Inoue,Yuhkoh Satouh,Kazuhiro Kaseda,Masahito Ikawa,Masaru Okabe,Journal of Cell Science,COMPANY OF BIOLOGISTS LTD,Vol. 123,No. 9,p. 1531-1536,2010年05月01日,研究論文(学術雑誌)
  • Transgenic mouse sperm that have green acrosome and red mitochondria allow visualization of sperm and their acrosome reaction in vivo,Hidetoshi Hasuwa,Yuko Muro,Masahito Ikawa,Noriko Kato,Yoshihide Tsujimoto,Masaru Okabe,Experimental Animals,INT PRESS EDITING CENTRE INC,Vol. 59,No. 1,p. 105-107,2010年03月11日
  • Humanized gene replacement in mice reveals the contribution of cancer stroma-derived HB-EGF to tumor growth,Tomoko Ichise,Satoshi Adachi,Minako Ohishi,Masahito Ikawa,Masaru Okabe,Ryo Iwamoto,Eisuke Mekada,Cell Structure and Function,JAPAN SOC CELL BIOLOGY,Vol. 35,No. 1,p. 3-13,2010年,研究論文(学術雑誌)
  • Identification and disruption of sperm-specific angiotensin converting enzyme-3 (ACE3) in mouse,Naokazu Inoue,Tatsuya Kasahara,Masahito Ikawa,Masaru Okabe,PLoS ONE,PUBLIC LIBRARY SCIENCE,Vol. 5,No. 4,2010年,研究論文(学術雑誌)
  • Introduction of a foreign gene into zebrafish and medaka cells using adenoviral vectors,Toshihiro Kawasaki,Kenji Saito,Kaoru Mitsui,Masahito Ikawa,Masakane Yamashita,Yoshihito Taniguchi,Shunichi Takeda,Kohnosuke Mitani,Noriyoshi Sakai,Zebrafish,MARY ANN LIEBERT INC,Vol. 6,No. 3,p. 253-258,2009年09月01日,研究論文(学術雑誌)
  • L-Amino acid oxidase plays a crucial role in host defense in the mammary glands,Kentaro Nagaoka,Fugaku Aoki,Mizuna Hayashi,Yoshikage Muroi,Toshihiro Sakurai,Kikuji Itoh,Masahito Ikawa,Masaru Okabe,Kazuhiko Imakawa,Senkiti Sakai,FASEB Journal,FEDERATION AMER SOC EXP BIOL,Vol. 23,No. 8,p. 2514-2520,2009年08月,研究論文(学術雑誌)
  • A histone H3 lysine 36 trimethyltransferase links Nkx2-5 to Wolf-Hirschhorn syndrome,Keisuke Nimura,Kiyoe Ura,Hidetaka Shiratori,Masato Ikawa,Masaru Okabe,Robert J. Schwartz,Yasufumi Kaneda,Nature,NATURE PUBLISHING GROUP,Vol. 460,No. 7252,p. 287-291,2009年07月09日,研究論文(学術雑誌)
  • Disruption of ADAM3 impairs the migration of sperm into oviduct in mouse,Ryo Yamaguchi,Yuko Muro,Ayako Isotani,Keizo Tokuhiro,Kazuhiro Takumi,Ibrahim Adham,Masahito Ikawa,Masaru Okabe,Biology of Reproduction,SOC STUDY REPRODUCTION,Vol. 81,No. 1,p. 142-146,2009年07月,研究論文(学術雑誌)
  • Peroxiredoxin 4 knockout results in elevated spermatogenic cell death via oxidative stress,Yoshihito Iuchi,Futoshi Okada,Satoshi Tsunoda,Noriko Kibe,Nobuyuki Shirasawa,Masahito Ikawa,Masaru Okabe,Yoshitaka Ikeda,Junichi Fujii,Biochemical Journal,PORTLAND PRESS LTD,Vol. 419,No. 1,p. 149-158,2009年04月,研究論文(学術雑誌)
  • Disruption of the novel gene fad104 causes rapid postnatal death and attenuation of cell proliferation, adhesion, spreading and migration,Makoto Nishizuka,Keishi Kishimoto,Ayumi Kato,Masahito Ikawa,Masaru Okabe,Ryuichiro Sato,Hiroyuki Niida,Makoto Nakanishi,Shigehiro Osada,Masayoshi Imagawa,Experimental Cell Research,ELSEVIER INC,Vol. 315,No. 5,p. 809-819,2009年03月10日,研究論文(学術雑誌)
  • Placenta-specific gene activation and inactivation using integrase-defective lentiviral vectors with the Cre/LoxP system,Yuka Morioka,Ayako Isotani,Robert G. Oshima,Masaru Okabe,Masahito Ikawa,Genesis,WILEY-LISS,Vol. 47,No. 12,p. 793-798,2009年,研究論文(学術雑誌)
  • Signalling mediated by the endoplasmic reticulum stress transducer OASIS is involved in bone formation,Tomohiko Murakami,Atsushi Saito,Shin Ichiro Hino,Shinichi Kondo,Soshi Kanemoto,Kazuyasu Chihara,Hiroshi Sekiya,Kenji Tsumagari,Kimiko Ochiai,Kazuya Yoshinaga,Masahiro Saitoh,Riko Nishimura,Toshiyuki Yoneda,Ikuyo Kou,Tatsuya Furuichi,Shiro Ikegawa,Masahito Ikawa,Masaru Okabe,Akio Wanaka,Kazunori Imaizumi,Nature Cell Biology,NATURE PUBLISHING GROUP,Vol. 11,No. 10,p. 1205-1211,2009年,研究論文(学術雑誌)
  • Regulation of endoplasmic reticulum stress response by a BBF2H7-mediated Sec23a pathway is essential for chondrogenesis,Atsushi Saito,Shin Ichiro Hino,Tomohiko Murakami,Soshi Kanemoto,Shinichi Kondo,Masahiro Saitoh,Riko Nishimura,Toshiyuki Yoneda,Tatsuya Furuichi,Shiro Ikegawa,Masahito Ikawa,Masaru Okabe,Kazunori Imaizumi,Nature Cell Biology,NATURE PUBLISHING GROUP,Vol. 11,No. 10,p. 1197-1204,2009年,研究論文(学術雑誌)
  • Male germline and embryonic stem cell lines from NOD mice: Efficient derivation of gs cells from a nonpermissive strain for ES cell derivation,Hiroshi Ohta,Yasuhide Ohinata,Masahito Ikawa,Yuka Morioka,Yuko Sakaide,Mitinori Saitou,Osami Kanagawa,Teruhiko Wakayama,Biology of Reproduction,SOC STUDY REPRODUCTION,Vol. 81,No. 6,p. 1147-1153,2009年,研究論文(学術雑誌)
  • Targeted gene modification in mouse ES cells using integrase-defective lentiviral vectors,Yuka Okada,Yuko Ueshin,Hidetoshi Hasuwa,Kazuhiro Takumi,Masaru Okabe,Masahito Ikawa,Genesis,WILEY-LISS,Vol. 47,No. 4,p. 217-223,2009年,研究論文(学術雑誌)
  • Putative sperm fusion protein IZUMO and the role of N-glycosylation,Naokazu Inoue,Masahito Ikawa,Masaru Okabe,Biochemical and Biophysical Research Communications,ACADEMIC PRESS INC ELSEVIER SCIENCE,Vol. 377,No. 3,p. 910-914,2008年12月19日,研究論文(学術雑誌)
  • Bis deficiency results in early lethality with metabolic deterioration and involution of spleen and thymus,Dong Ye Youn,Dong Hyoung Lee,Mi Hyun Lim,Jung Sook Yoon,Hee Lim Ji,Eun Jung Seung,Eun Yeum Chung,Whee Park Cheol,Ho Joong Youn,Jae Seon Lee,Seong Beom Lee,Masahito Ikawa,Masaru Okabe,Yoshihide Tsujimoto,Jeong Hwa Lee,American Journal of Physiology - Endocrinology and Metabolism,AMER PHYSIOLOGICAL SOC,Vol. 295,No. 6,p. E1349-E1357,2008年12月,研究論文(学術雑誌)
  • Role of calnexin in the ER quality control and productive folding of CFTR; differential effect of calnexin knockout on wild-type and ΔF508 CFTR,Tsukasa Okiyoneda,Akiko Niibori,Kazutsune Harada,Taijun Kohno,Marek Michalak,Marek Duszyk,Ikuo Wada,Masahito Ikawa,Tsuyoshi Shuto,Mary Ann Suico,Hirofumi Kai,Biochimica et Biophysica Acta - Molecular Cell Research,ELSEVIER SCIENCE BV,Vol. 1783,No. 9,p. 1585-1594,2008年09月,研究論文(学術雑誌)
  • Taurine depletion caused by knocking out the taurine transporter gene leads to cardiomyopathy with cardiac atrophy,Takashi Ito,Yasushi Kimura,Yoriko Uozumi,Mika Takai,Satoko Muraoka,Takahisa Matsuda,Kei Ueki,Minoru Yoshiyama,Masahito Ikawa,Masaru Okabe,Stephen W. Schaffer,Yasushi Fujio,Junichi Azuma,Journal of Molecular and Cellular Cardiology,ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD,Vol. 44,No. 5,p. 927-937,2008年05月,研究論文(学術雑誌)
  • Pluripotency of a single spermatogonial stem cell in mice,Mito Kanatsu-Shinohara,Jiyoung Lee,Kimiko Inoue,Narumi Ogonuki,Hiromi Miki,Shinya Toyokuni,Masahito Ikawa,Tomoyuki Nakamura,Atsuo Ogura,Takashi Shinohara,Biology of Reproduction,SOC STUDY REPRODUCTION,Vol. 78,No. 4,p. 681-687,2008年04月,研究論文(学術雑誌)
  • DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes,Satomi Kuramochi-Miyagawa,Toshiaki Watanabe,Kengo Gotoh,Yasushi Totoki,Atsushi Toyoda,Masahito Ikawa,Noriko Asada,Kanako Kojima,Yuka Yamaguchi,Takashi W. Ijiri,Kenichiro Hata,En Li,Yoichi Matsuda,Tohru Kimura,Masaru Okabe,Yoshiyuki Sakaki,Hiroyuki Sasaki,Toru Nakano,Genes and Development,COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT,Vol. 22,No. 7,p. 908-917,2008年04月,研究論文(学術雑誌)
  • Neuroaxonal dystrophy caused by group VIA phospholipase A<inf>2</inf> deficiency in mice: A model of human neurodegenerative disease,Koei Shinzawa,Hisae Sumi,Masahito Ikawa,Yosuke Matsuoka,Masaru Okabe,Saburo Sakoda,Yoshihide Tsujimoto,Journal of Neuroscience,SOC NEUROSCIENCE,Vol. 28,No. 9,p. 2212-2220,2008年02月27日,研究論文(学術雑誌)
  • Ghrelin deficiency does not influence feeding performance,Takahiro Sato,Mamoru Kurokawa,Yoshiki Nakashima,Takanori Ida,Tomoko Takahashi,Yoshihiko Fukue,Masahito Ikawa,Masaru Okabe,Kenji Kangawa,Masayasu Kojima,Regulatory Peptides,ELSEVIER SCIENCE BV,Vol. 145,No. 1-3,p. 7-11,2008年01月10日
  • Disruption of miR-200b leads to female infertility,Hidetoshi Hasuwa,Masahito Ikawa,Masaru Okabe,BIOLOGY OF REPRODUCTION,SOC STUDY REPRODUCTION,p. 213-213,2008年
  • Cd52, known as a major maturation-associated sperm membrane antigen secreted from the epididymis, is not required for fertilization in the mouse,Ryo Yamaguchi,Kazuo Yamagata,Hidetoshi Hasuwa,Emiko Inano,Masahito Ikawa,Masaru Okabe,Genes to Cells,BLACKWELL PUBLISHING,Vol. 13,No. 8,p. 851-861,2008年,研究論文(学術雑誌)
  • Mechanisms of sperm-egg interactions emerging from gene-manipulated animals,Masahito Ikawa,Naokazu Inoue,Masaru Okabe,International Journal of Developmental Biology,U B C PRESS,Vol. 52,No. 5-6,p. 657-664,2008年
  • Innate versus learned odour processing in the mouse olfactory bulb,Ko Kobayakawa,Reiko Kobayakawa,Hideyuki Matsumoto,Yuichiro Oka,Takeshi Imai,Masahito Ikawa,Masaru Okabe,Toshio Ikeda,Shigeyoshi Itohara,Takefumi Kikusui,Kensaku Mori,Hitoshi Sakano,Nature,NATURE PUBLISHING GROUP,Vol. 450,No. 7169,p. 503-508,2007年11月21日,研究論文(学術雑誌)
  • Efficient derivation of embryonic stem cells by inhibition of glycogen synthase kinase-3,Hiroki Umehara,Tohru Kimura,Satoshi Ohtsuka,Toshinobu Nakamura,Kenji Kitajima,Masahito Ikawa,Masaru Okabe,Hitoshi Niwa,Toru Nakano,Stem Cells,WILEY-BLACKWELL,Vol. 25,No. 11,p. 2705-2711,2007年11月,研究論文(学術雑誌)
  • PGAP1 knock-out mice show otocephaly and male infertility,Yasutaka Ueda,Ryo Yamaguchi,Masahito Ikawa,Masaru Okabe,Eiichi Morii,Yusuke Maeda,Taroh Kinoshita,Journal of Biological Chemistry,AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC,Vol. 282,No. 42,p. 30373-30380,2007年10月19日,研究論文(学術雑誌)
  • Hypertension and dysregulated proinflammatory cytokine production in receptor activity-modifying protein 1-deficient mice,Kazutake Tsujikawa,Katsutoshi Yayama,Tamon Hayashi,Hiroaki Matsushita,Taijiro Yamaguchi,Tomomi Shigeno,Yusuke Ogitani,Megumi Hirayama,Tetsuya Kato,So Ichiro Fukada,Shingo Takatori,Hiromu Kawasaki,Hiroshi Okamoto,Masahito Ikawa,Masaru Okabe,Hiroshi Yamamoto,Proceedings of the National Academy of Sciences of the United States of America,NATL ACAD SCIENCES,Vol. 104,No. 42,p. 16702-16707,2007年10月16日,研究論文(学術雑誌)
  • Lats2 is an essential mitotic regulator required for the coordination of cell division,Norikazu Yabuta,Nobuhiro Okada,Akihiko Ito,Toshiya Hosomi,Souichi Nishihara,Yuya Sasayama,Azumi Fujimori,Daisuke Okuzaki,Hanjun Zhao,Masahito Ikawa,Masaru Okabe,Hiroshi Nojima,Journal of Biological Chemistry,AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC,Vol. 282,No. 26,p. 19259-19271,2007年06月29日,研究論文(学術雑誌)
  • Mcp4, a meiotic coiled-coil protein, plays a role in F-actin positioning during Schizosaccharomyces pombe meiosis,Ayami Ohtaka,Daisuke Okuzaki,Takamune T. Saito,Hiroshi Nojima,EUKARYOTIC CELL,AMER SOC MICROBIOLOGY,Vol. 6,No. 6,p. 971-983,2007年06月,研究論文(学術雑誌)
  • Antitumor NK activation induced by the Toll-like receptor 3-TICAM-1 (TRIF) pathway in myeloid dendritic cells,Takashi Akazawa,Takashi Ebihara,Manabu Okuno,Yu Okuda,Masashi Shingai,Kunio Tsujimura,Toshitada Takahashi,Masahito Ikawa,Masaru Okabe,Norimitsu Inoue,Miki Okamoto-Tanaka,Hiroyoshi Ishizaki,Jun Miyoshi,Misako Matsumoto,Tsukasa Seya,Proceedings of the National Academy of Sciences of the United States of America,NATL ACAD SCIENCES,Vol. 104,No. 1,p. 252-257,2007年01月02日,研究論文(学術雑誌)
  • Sperm-egg interaction and gene manipulated animals.,Naokazu Inoue,Ryo Yamaguchi,Masahito Ikawa,Masaru Okabe,Society of Reproduction and Fertility supplement,Vol. 65,p. 363-371,2007年
  • PGC7/Stella protects against DNA demethylation in early embryogenesis,Toshinobu Nakamura,Yoshikazu Arai,Hiroki Umehara,Masaaki Masuhara,Tohru Kimura,Hisaaki Taniguchi,Toshihiro Sekimoto,Masahito Ikawa,Yoshihiro Yoneda,Masaru Okabe,Satoshi Tanaka,Kunio Shiota,Toru Nakano,Nature Cell Biology,NATURE PUBLISHING GROUP,Vol. 9,No. 1,p. 64-71,2007年01月,研究論文(学術雑誌)
  • Aberrant distribution of ADAM3 in sperm from both angiotensin-converting enzyme (Ace)- and calmegin (Clgn)-deficient mice,Ryo Yamaguchi,Kazuo Yamagata,Masahito Ikawa,Stuart B. Moss,Masaru Okabe,Biology of Reproduction,SOC STUDY REPRODUCTION,Vol. 75,No. 5,p. 760-766,2006年11月,研究論文(学術雑誌)
  • The testes-specific bZip type transcription factor Tisp40 plays a role in ER stress responses and chromatin packaging during spermiogenesis,Ippei Nagamori,Kentaro Yomogida,Masahito Ikawa,Masaru Okabe,Norikazu Yabuta,Hiroshi Nojima,Genes to Cells,WILEY-BLACKWELL,Vol. 11,No. 10,p. 1161-1171,2006年10月,研究論文(学術雑誌)
  • Rapid generation of knockdown transgenic mice by silencing lentiviral vectors,Oded Singer,Gustavo Tiscornia,Masahito Ikawa,Inder M. Verma,Nature Protocols,NATURE PUBLISHING GROUP,Vol. 1,No. 1,p. 286-292,2006年06月,研究論文(学術雑誌)
  • Deletion of SERP1/RAMP4, a component of the endoplasmic reticulum (ER) translocation sites, leads to ER stress,Osamu Hori,Mayuki Miyazaki,Takashi Tamatani,Kentaro Ozawa,Katsura Takano,Masaru Okabe,Masahito Ikawa,Enno Hartmann,Petra Mai,David M. Stern,Yasuko Kitao,Satoshi Ogawa,Molecular and Cellular Biology,AMER SOC MICROBIOLOGY,Vol. 26,No. 11,p. 4257-4267,2006年06月,研究論文(学術雑誌)
  • Plexin-A1 and its interaction with DAP12 in immune responses and bone homeostasis,Noriko Takegahara,Hyota Takamatsu,Toshihiko Toyofuku,Tohru Tsujimura,Tatsusada Okuno,Kazunori Yukawa,Masayuki Mizui,Midori Yamamoto,Durbaka V.R. Prasad,Kazuhiro Suzuki,Masaru Ishii,Kenta Terai,Masayuki Moriya,Yuji Nakatsuji,Saburo Sakoda,Shintaro Sato,Shizuo Akira,Kiyoshi Takeda,Masanori Inui,Toshiyuki Takai,Masahito Ikawa,Masaru Okabe,Atsushi Kumanogoh,Hitoshi Kikutani,Nature Cell Biology,NATURE PUBLISHING GROUP,Vol. 8,No. 6,p. 615-622,2006年06月,研究論文(学術雑誌)
  • Production of knockout mice by random or targeted mutagenesis in spermatogonial stem cells,Mito Kanatsu-Shinohara,Masahito Ikawa,Masanori Takehashi,Narumi Ogonuki,Hiromi Miki,Kimiko Inoue,Yasuhiro Kazuki,Jiyoung Lee,Shinya Toyokuni,Mitsuo Oshimura,Atsuo Ogura,Takashi Shinohara,Proceedings of the National Academy of Sciences of the United States of America,NATL ACAD SCIENCES,Vol. 103,No. 21,p. 8018-8023,2006年05月23日,研究論文(学術雑誌)
  • Choroidal neovascularization in transgenic mice expressing prokineticin 1: An animal model for age-related macular degeneration,Nobushige Tanaka,Masahito Ikawa,Nathan L. Mata,Inder M. Verma,Molecular Therapy,ACADEMIC PRESS INC ELSEVIER SCIENCE,Vol. 13,No. 3,p. 609-616,2006年03月,研究論文(学術雑誌)
  • Comparison of gene expression in male and female mouse blastocysts revealed imprinting of the X-linked gene, Rhox5/Pem, at preimplantation stages,Shin Kobayashi,Ayako Isotani,Nathan Mise,Masamichi Yamamoto,Yoshitaka Fujihara,Kazuhiro Kaseda,Tomoko Nakanishi,Masahito Ikawa,Hiroshi Hamada,Kuniya Abe,Masaru Okabe,Current Biology,CELL PRESS,Vol. 16,No. 2,p. 166-172,2006年01月24日,研究論文(学術雑誌)
  • Analysis of mice that show abnormal expression of neuroglycan C, a central nervous system-specific transmembrane proteoglycan,Sachiko Aono,Yoshiyuki Kuroda,Fumiko Matsui,Yoshihito Tokita,Keiko Nakanishi,Michiru Ida,Masahito Ikawa,Masaru Okabe,Katsuhiko Ono,Atsuhiko Oohira,NEUROSCIENCE RESEARCH,ELSEVIER IRELAND LTD,Vol. 55,p. S186-S186,2006年
  • RECS1 deficiency in mice induces susceptibility to cystic medial degeneration,Hanjun Zhao,Akihiko Ito,Shinya H. Kimura,Norikazu Yabuta,Naohiko Sakai,Masahito Ikawa,Masaru Okabe,Yuji Matsuzawa,Shizuya Yamashita,Hiroshi Nojima,Genes and Genetic Systems,GENETICS SOC JAPAN,Vol. 81,No. 1,p. 41-50,2006年,研究論文(学術雑誌)
  • Distinct roles of IκB proteins in regulating constitutive NF-κB activity,Vinay Tergaonkar,Ricardo G. Correa,Masahito Ikawa,Inder M. Verma,Nature Cell Biology,NATURE PUBLISHING GROUP,Vol. 7,No. 9,p. 921-923,2005年09月,研究論文(学術雑誌)
  • Impaired urea accumulation in the inner medulla of mice lacking the urea transporter UT-A2,Shinichi Uchida,Eisei Sohara,Tatemitsu Rai,Masahito Ikawa,Masaru Okabe,Sei Sasaki,Molecular and Cellular Biology,AMER SOC MICROBIOLOGY,Vol. 25,No. 16,p. 7357-7363,2005年08月,研究論文(学術雑誌)
  • Progressive adipocyte hypertrophy in aquaporin-7-deficient mice: Adipocyte glycerol permeability as a novel regulator of fat accumulation,Mariko Hara-Chikuma,Eisei Sohara,Tatemitsu Rai,Masahito Ikawa,Masaru Okabe,Sei Sasaki,Shinichi Uchida,A. S. Verkman,Journal of Biological Chemistry,AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC,Vol. 280,No. 16,p. 15493-15496,2005年04月,研究論文(学術雑誌)
  • Neuromedin U has a novel anorexigenic effect independent of the leptin signaling pathway,Reiko Hanada,Hitoshi Teranishi,James Todd Pearson,Mamoru Kurokawa,Hiroshi Hosoda,Nobuhiro Fukushima,Yoshihiko Fukue,Ryota Serino,Hiroaki Fujihara,Yoichi Ueta,Masahito Ikawa,Masaru Okabe,Noboru Murakami,Mikiyasu Shirai,Hironobu Yoshimatsu,Kenji Kangawa,Masayasu Kojima,Nature Medicine,NATURE PUBLISHING GROUP,Vol. 10,No. 10,p. 1067-1073,2004年10月,研究論文(学術雑誌)
  • Selective passage through the uterotubal junction of sperm from a mixed population produced by chimeras of calmegin-knockout and wild-type male mice,Tomoko Nakanishi,Ayako Isotani,Ryo Yamaguchi,Masahito Ikawa,Tadashi Baba,Susan S. Suarez,Masaru Okabe,Biology of Reproduction,SOC STUDY REPRODUCTION,Vol. 71,No. 3,p. 959-965,2004年09月,研究論文(学術雑誌)
  • Lineage-specific cell disruption in living mice by Cre-mediated expression of diphtheria toxin A chain,Hiroyuki Matsumura,Hidetoshi Hasuwa,Naokazu Inoue,Masahito Ikawa,Masaru Okabe,Biochemical and Biophysical Research Communications,ACADEMIC PRESS INC ELSEVIER SCIENCE,Vol. 321,No. 2,p. 275-279,2004年08月20日,研究論文(学術雑誌)
  • The LIM homeobox gene, L3/Lhx8, is necessary for proper development of basal forebrain cholinergic neurons,Tetsuji Mori,Zhang Yuxing,Hiromi Takaki,Mayumi Takeuchi,Ken Iseki,Seita Hagino,Jun Ichi Kitanaka,Motohiko Takemura,Hidemi Misawa,Masahito Ikawa,Masaru Okabe,Akio Wanaka,European Journal of Neuroscience,BLACKWELL PUBLISHING LTD,Vol. 19,No. 12,p. 3129-3141,2004年06月,研究論文(学術雑誌)
  • Identification of the XPG Region That Causes the Onset of Cockayne Syndrome by Using Xpg Mutant Mice Generated by the cDNA-Mediated Knock-In Method,Naoko Shiomi,Seiji Kito,Masaki Oyama,Tsukasa Matsunaga,Yoshi Nobu Harada,Masahito Ikawa,Masaru Okabe,Tadahiro Shiomi,Molecular and Cellular Biology,AMER SOC MICROBIOLOGY,Vol. 24,No. 9,p. 3712-3719,2004年05月,研究論文(学術雑誌)
  • Mili, a mammalian member of piwi family gene, is essential for spermatogenesis,Satomi Kuramochi-Miyagawa,Tohru Kimura,Takashi W. Ijiri,Taku Isobe,Noriko Asada,Yukiko Fujita,Masahito Ikawa,Naomi Iwai,Masaru Okabe,Wei Deng,Haifan Lin,Yoichi Matsuda,Toru Nakano,Development,COMPANY OF BIOLOGISTS LTD,Vol. 131,No. 4,p. 839-849,2004年02月,研究論文(学術雑誌)
  • IκB Kinase-Independent IκBα Degradation Pathway: Functional NF-κB Activity and Implications for Cancer Therapy,Vinay Tergaonkar,Virginie Bottero,Masahito Ikawa,Qiutang Li,Inder M. Verma,Molecular and Cellular Biology,AMER SOC MICROBIOLOGY,Vol. 23,No. 22,p. 8070-8083,2003年11月,研究論文(学術雑誌)
  • Generation of transgenic mice using lentiviral vectors: A novel preclinical assessment of lectiviral vectors for gene therapy,Masahito Ikawa,Nobushige Tanaka,Winston W.Y. Kao,Inder M. Verma,Molecular Therapy,ACADEMIC PRESS INC ELSEVIER SCIENCE,Vol. 8,No. 4,p. 666-673,2003年10月,研究論文(学術雑誌)
  • Disruption of mouse CD46 causes an accelerated spontaneous acrosome reaction in sperm,Naokazu Inoue,Masahito Ikawa,Tomoko Nakanishi,Misako Matsumoto,Midori Nomura,Tsukasa Seya,Masaru Okabe,Molecular and Cellular Biology,AMER SOC MICROBIOLOGY,Vol. 23,No. 7,p. 2614-2622,2003年04月,研究論文(学術雑誌)
  • A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA,Gustavo Tiscornia,Oded Singer,Masahito Ikawa,Inder M. Verma,Proceedings of the National Academy of Sciences of the United States of America,NATL ACAD SCIENCES,Vol. 100,No. 4,p. 1844-1848,2003年02月18日,研究論文(学術雑誌)
  • Mouse germ cell-less as an essential component for nuclear integrity,Tohru Kimura,Chizuru Ito,Shoko Watanabe,Tohru Takahashi,Masahito Ikawa,Kentaro Yomogida,Yukiko Fujita,Megumi Ikeuchi,Noriko Asada,Kiyomi Matsumiya,Akihiko Okuyama,Masaru Okabe,Kiyotaka Toshimori,Toru Nakano,Molecular and Cellular Biology,AMER SOC MICROBIOLOGY,Vol. 23,No. 4,p. 1304-1315,2003年02月,研究論文(学術雑誌)
  • Mouse sperm lacking cell surface hyaluronidase PH-20 can pass through the layer of cumulus cells and fertilize the egg.,Daichi Baba,Shin ichi Kashiwabara,Arata Honda,Kazuo Yamagata,Qing Wu,Masahito Ikawa,Masaru Okabe,Tadashi Baba,The Journal of biological chemistry,AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC,Vol. 277,No. 33,p. 30310-30314,2002年08月16日,研究論文(学術雑誌)
  • Transgenesis by lentiviral vectors: Lack of gene silencing in mammalian embryonic stem cells and preimplantation embryos,Alexander Pfeifer,Masahito Ikawa,Yelena Dayn,Inder M. Verma,Proceedings of the National Academy of Sciences of the United States of America,NATL ACAD SCIENCES,Vol. 99,No. 4,p. 2140-2145,2002年02月19日,研究論文(学術雑誌)
  • Fish analysis of 142 EGFP transgene integration sites into the mouse genome,Tomoko Nakanishi,Asato Kuroiwa,Shuichi Yamada,Ayako Isotani,Atsuko Yamashita,Ai Tairaka,Tamon Hayashi,Tatsuya Takagi,Masahito Ikawa,Yoichi Matsuda,Masaru Okabe,Genomics,ACADEMIC PRESS INC ELSEVIER SCIENCE,Vol. 80,No. 6,p. 564-574,2002年,研究論文(学術雑誌)
  • Sperm from the calmegin-deficient mouse have normal abilities for binding and fusion to the egg plasma membrane,Kazuo Yamagata,Tomoko Nakanishi,Masahito Ikawa,Ryou Yamaguchi,Stuart B. Moss,Masaru Okabe,Developmental Biology,ACADEMIC PRESS INC ELSEVIER SCIENCE,Vol. 250,No. 2,p. 348-357,2002年,研究論文(学術雑誌)
  • Calmegin is required for fertilin α/β heterodimerization and sperm fertility,Masahito Ikawa,Tomoko Nakanishi,Shuichi Yamada,Ikuo Wada,Katsuya Kominami,Hiromitsu Tanaka,Masami Nozaki,Yoshitake Nishimune,Masaru Okabe,Developmental Biology,ACADEMIC PRESS INC ELSEVIER SCIENCE,Vol. 240,No. 1,p. 254-261,2001年12月01日,研究論文(学術雑誌)
  • Alkalinization of acrosome measured by GFP as a pH indicator and its relation to sperm capacitation,Tomoko Nakanishi,Masahito Ikawa,Shuichi Yamada,Kiyotaka Toshimori,Masaru Okabe,Developmental Biology,ACADEMIC PRESS INC,Vol. 237,No. 1,p. 222-231,2001年09月01日,研究論文(学術雑誌)
  • Efficient chromosomal transposition of a Tc1/mariner-like transposon Sleeping Beauty in mice,Kyoji Horie,Asato Kuroiwa,Masahito Ikawa,Masaru Okabe,Gen Kondoh,Yoichi Matsuda,Junji Takeda,Proceedings of the National Academy of Sciences of the United States of America,NATL ACAD SCIENCES,Vol. 98,No. 16,p. 9191-9196,2001年07月31日,研究論文(学術雑誌)
  • A synthetic DAF (CD55) gene based on optimal codon usage for transgenic animals,Shuji Miyagawa,Mako Yamada,Katsuyoshi Matsunami,Yukie Koresawa,Masahito Ikawa,Masaru Okabe,Ryota Shirakura,Journal of Biochemistry,JAPANESE BIOCHEMICAL SOC,Vol. 129,No. 5,p. 795-801,2001年05月,研究論文(学術雑誌)
  • Expression of the endoplasmic reticulum molecular chaperone (ORP150) rescues hippocampal neurons from glutamate toxicity,Yasuko Kitao,Kentaro Ozawa,Mayuki Miyazaki,Michio Tamatani,Tomohiro Kobayashi,Hideki Yanagi,Masaru Okabe,Masahito Ikawa,Tetsumori Yamashima,David M. Stern,Osamu Hori,Satoshi Ogawa,Journal of Clinical Investigation,AMER SOC CLINICAL INVESTIGATION INC,Vol. 108,No. 10,p. 1439-1450,2001年,研究論文(学術雑誌)
  • Cyclin G1 is involved in G2/M arrest in response to DNA damage and in growth control after damage recovery,Shinya H. Kimura,Masahito Ikawa,Akihiko Ito,Masaru Okabe,Hiroshi Nojima,Oncogene,NATURE PUBLISHING GROUP,Vol. 20,No. 25,p. 3290-3300,2001年,研究論文(学術雑誌)
  • A codon exchange DAF is a powerful material for xenografting,M. Yamada,S. Miyagawa,K. Matsunami,Y. Koresawa,T. Kurihara,M. Ikawa,M. Okabe,R. Shirakura,Transplantation Proceedings,ELSEVIER SCIENCE INC,Vol. 33,No. 1-2,p. 744-745,2001年,研究論文(国際会議プロシーディングス)
  • Erratum: Homeobox gene Hex is essential for onset of mouse embryonic liver development and differentiation of the monocyte lineage (Biochemical and Biophysical Research Communication (2000) 276:3 (1155-1161)),V. W. Keng,H. Yagi,M. Ikawa,T. Nagano,Z. Myint,K. Yamada,T. Tanaka,A. Sato,I. Muramatsu,M. Okabe,M. Sato,T. Noguchi,Biochemical and Biophysical Research Communications,Vol. 279,No. 2,2000年12月20日,研究論文(学術雑誌)
  • Green fluorescent protein-transgenic mice: Immune functions and their application to studies of lymphocyte development,Naoto Kawakami,Naoki Sakane,Fumiko Nishizawa,Mutsumi Iwao,So Ichiro Fukada,Kazutake Tsujikawa,Yasuhiro Kohama,Masahito Ikawa,Masaru Okabe,Hiroshi Yamamoto,Immunology Letters,ELSEVIER SCIENCE BV,Vol. 70,No. 3,p. 165-171,2000年12月01日,研究論文(学術雑誌)
  • Homeobox gene Hex is essential for onset of mouse embryonic liver development and differentiation of the monocyte lineage,Vincent W. Keng,Hideshi Yagi,Masahito Ikawa,Takashi Nagano,Zaw Myint,Kazuya Yamada,Takashi Tanaka,Ayuko Sato,Ikunobu Muramatsu,Masaru Okabe,Makoto Sato,Tamio Noguchi,Biochemical and Biophysical Research Communications,Vol. 276,No. 3,p. 1155-1161,2000年10月05日,研究論文(学術雑誌)
  • The class IV semaphorin CD100 plays nonredundant roles in the immune system: Defective B and T cell activation in CD100-deficient mice,Wei Shi,Atsushi Kumanogoh,Chie Watanabe,Junji Uchida,Xiaosong Wang,Teruhito Yasui,Kazunori Yukawa,Masahito Ikawa,Masaru Okabe,Jane R. Parnes,Kanji Yoshida,Hitoshi Kikutani,Immunity,CELL PRESS,Vol. 13,No. 5,p. 633-642,2000年,研究論文(学術雑誌)
  • Mice with markedly reduced PACAP (PAC<inf>1</inf>) receptor expression by targeted deletion of the signal peptide,Hitoshi Hashimoto,Norihito Shintani,Akiko Nishino,Masaru Okabe,Masahito Ikawa,Shogo Matsuyama,Kyoko Itoh,Kyohei Yamamoto,Shuhei Tomimoto,Takashi Fujita,Nami Hagihara,Wakaba Mori,Yutaka Koyama,Toshio Matsuda,Shigekazu Nagata,Akemichi Baba,Journal of Neurochemistry,LIPPINCOTT WILLIAMS & WILKINS,Vol. 75,No. 5,p. 1810-1817,2000年,研究論文(学術雑誌)
  • A new Cre recombinase gene based on optimal codon usage in mammals: A powerful material for organ-specific gene targeting,Y. Koresawa,S. Miyagawa,M. Ikawa,K. Matsunami,M. Yamada,M. Okabe,R. Shirakura,Transplantation Proceedings,ELSEVIER SCIENCE INC,Vol. 32,No. 7,p. 2516-2517,2000年,研究論文(学術雑誌)
  • Synthesis of a new Cre recombinase gene based on optimal codon usage for mammalian systems,Yukie Koresawa,Shuji Miyagawa,Masahito Ikawa,Katsuyoshi Matsunami,Mako Yamada,Ryota Shirakura,Masaru Okabe,Journal of Biochemistry,JAPANESE BIOCHEMICAL SOC,Vol. 127,No. 3,p. 367-372,2000年,研究論文(学術雑誌)
  • Roles of integrins and CD44 on the adhesion and migration of fetal liver cells to the fetal thymus,Naoto Kawakami,Fumiko Nishizawa,Naoki Sakane,Mutsumi Iwao,Kazutake Tsujikawa,Masahito Ikawa,Masaru Okabe,Hiroshi Yamamoto,Journal of Immunology,AMER ASSOC IMMUNOLOGISTS,Vol. 163,No. 6,p. 3211-3216,1999年09月15日,研究論文(学術雑誌)
  • Migration of exogenous immature hematopoietic cells into adult mouse brain parenchyma under GFP-expressing bone marrow chimera,Kenji Ono,Takemasa Takii,Kikuo Onozaki,Masahito Ikawa,Masaru Okabe,Makoto Sawada,Biochemical and Biophysical Research Communications,ACADEMIC PRESS INC,Vol. 262,No. 3,p. 610-614,1999年09月07日,研究論文(学術雑誌)
  • Mutation in ankyrin repeats of the mouse Notch2 gene induces early embryonic lethality,Yoshio Hamada,Yuzo Kadokawa,Masaru Okabe,Masahito Ikawa,John R. Coleman,Yoshihide Tsujimoto,Development,COMPANY OF BIOLOGISTS LTD,Vol. 126,No. 15,p. 3415-3424,1999年08月,研究論文(学術雑誌)
  • Real-time observation of acrosomal dispersal from mouse sperm using GFP as a marker protein,Tomoko Nakanishi,Masahito Ikawa,Shuichi Yamada,Martti Parvinen,Tadashi Baba,Yoshitake Nishimune,Masaru Okabe,FEBS Letters,ELSEVIER SCIENCE BV,Vol. 449,No. 2-3,p. 277-283,1999年04月,研究論文(学術雑誌)
  • Postnatal growth failure, short life span, and early onset of cellular senescence and subsequent immortalization in mice lacking the xeroderma pigmentosum group G gene,Yoshi Nobu Harada,Naoko Shiomi,Manabu Koike,Masahito Ikawa,Masaru Okabe,Seiichi Hirota,Yukihiko Kitamura,Masanobu Kitagawa,Tsukasa Matsunaga,Osamu Nikaido,Tadahiro Shiomi,Molecular and Cellular Biology,AMER SOC MICROBIOLOGY,Vol. 19,No. 3,p. 2366-2372,1999年03月,研究論文(学術雑誌)
  • Green fluorescent protein (GFP) as a marker for cell viability after UV irradiation,C. Baumstark-Khan,M. Palm,J. Wehner,M. Okabe,M. Ikawa,G. Horneck,Journal of Fluorescence,Kluwer Academic/Plenum Publishers,Vol. 9,No. 1,p. 37-43,1999年,研究論文(学術雑誌)
  • The putative chaperone calmegin and sperm fertility.,M Okabe,M Ikawa,S Yamada,T Nakanishi,T Baba,Y Nishimune,MALE GAMETE: FROM BASIC SCIENCE TO CLINICAL APPLICATIONS,CACHE RIVER PRESS,p. 47-54,1999年,研究論文(国際会議プロシーディングス)
  • Efficient selection of transgenic mouse embryos using EGFP as a marker gene,Minoru Kato,Keitaro Yamanouchi,Masahito Ikawa,Masaru Okabe,Kunihiko Naito,Hideaki Tojo,Molecular Reproduction and Development,WILEY-LISS,Vol. 54,No. 1,p. 43-48,1999年,研究論文(学術雑誌)
  • Glowing podocytes in living mouse: Transgenic mouse carrying a podocyte- specific promoter,Enyu Imai,Yoshitaka Akagi,Yoshitaka Isaka,Masahito Ikawa,Masaru Takenaka,Masatsugu Hori,Masaru Okabe,Experimental Nephrology,KARGER,Vol. 7,No. 1,p. 63-66,1999年,研究論文(国際会議プロシーディングス)
  • Studies on the Mechanism of Sperm Prodution,Tanaka H,Okabe M,Ikawa M,Tsuchida J,Yoshimura Y,Yomogida Y,Nishimune Y,Testicular Function: From Gene Expression to Genetic Manipulation.,Springer,Vol. 235-254,1998年10月
  • Generating green fluorescent mice by germline transmission of green fluorescent ES cells,Anna Katerina Hadjantonakis,Marina Gertsenstein,Masahito Ikawa,Masaru Okabe,Andras Nagy,Mechanisms of Development,ELSEVIER SCIENCE BV,Vol. 76,No. 1-2,p. 79-90,1998年08月,研究論文(学術雑誌)
  • 'Green mice' and their potential usage in biological research,Masahito Ikawa,Shuichi Yamada,Tomoko Nakanishi,Masaru Okabe,FEBS Letters,ELSEVIER SCIENCE BV,Vol. 430,No. 1-2,p. 83-87,1998年06月23日,研究論文(国際会議プロシーディングス)
  • Prevention of hyperacute rejection by phosphatidylinositol-anchored mini-complement receptor type 1,Shoki Mikata,Shuji Miyagawa,Masao Yoshitatsu,Masato Ikawa,Masaru Okabe,Hikaru Matsuda,Ryota Shirakura,Transplant Immunology,ARNOLD, HODDER HEADLINE PLC,Vol. 6,No. 2,p. 107-110,1998年06月,研究論文(学術雑誌)
  • Gametogenesis '98: Male infertility and the genetics of spermatogenesis,Masaru Okabe,Masahito Ikawa,John Ashkenas,American Journal of Human Genetics,UNIV CHICAGO PRESS,Vol. 62,No. 6,p. 1274-1281,1998年06月,研究論文(学術雑誌)
  • Defective stratum corneum and early neonatal death in mice lacking the gene for transglutaminase 1 (keratinocyte transglutaminase),Masato Matsuki,Fumiyoshi Yamashita,Akemi Ishida-Yamamoto,Keiko Yamada,Chikako Kinoshita,Shinji Fushiki,Eiichiro Ueda,Yohichi Morishima,Kohichi Tabata,Hirokazu Yasuno,Mitsuru Hashida,Hajime Iizuka,Masahito Ikawa,Masaru Okabe,Gen Kondoh,Taroh Kinoshita,Junji Takeda,Kiyofumi Yamanishi,Proceedings of the National Academy of Sciences of the United States of America,NATL ACAD SCIENCES,Vol. 95,No. 3,p. 1044-1049,1998年02月03日,研究論文(学術雑誌)
  • The putative chaperone calmegin is required for sperm fertility,Masahito Ikawa,Ikuo Wada,Katsuya Kominami,Daisuke Watanabe,Kiyotaka Toshimori,Yoshitake Nishimune,Masaru Okabe,Zygote,Vol. 6,No. 1 SUPPL.,1998年,研究論文(学術雑誌)
  • Green fluorescent protein and its usage in reproductive biology,Masaru Okabe,Masahito Ikawa,Tomoko Nakanishi,Shuichi Yamada,Tadashi Baba,Yoshitake Nishimune,Zygote,Vol. 6,No. 1 SUPPL.,1998年,研究論文(学術雑誌)
  • Induction of EAE by Th1-type, GFP<sup>+</sup> MOG-specific T cells in C57BL/6 mice,Mamoru Yura,Masashi Serada,Ichiro Takahashi,Hiroshi Kiyono,Takehiro Koshio,Keiji Nakagami,Masahito Ikawa,Masaru Okabe,Japanese Journal of Clinical Immunology,Vol. 21,p. 125-134,1998年,研究論文(学術雑誌)
  • The putative chaperone calmegin is required for sperm fertility,M. Ikawa,I. Wada,K. Kominami,D. Watanabe,K. Toshimori,Y. Nishimune,M. Okabe,Journal of Urology,Lippincott Williams and Wilkins,Vol. 160,No. 2,1998年,研究論文(学術雑誌)
  • Non-invasive sexing of preimplantation stage mammalian embryos [2],A. K. Hadjantonakis,M. Gertsenstein,M. Ikawa,M. Okabe,A. Nagy,Nature Genetics,NATURE AMERICA INC,Vol. 19,No. 3,p. 220-222,1998年
  • 1 Green Fluorescent Protein (GFP) as a Vital Marker in Mammals,Masahito Ikawa,Shuichi Yamada,Tomoko Nakanishi,Masaru Okabe,Current Topics in Developmental Biology,ACADEMIC PRESS INC,Vol. 44,No. C,p. 1-6,1998年01月01日,研究論文(学術雑誌)
  • Cloning and characterization of the human Calmegin gene encoding putative testis-specific chaperone,Hiromitsu Tanaka,Masahito Ikawa,Junji Tsuchida,Masami Nozaki,Mikio Suzuki,Tsutomu Fujiwara,Masaru Okabe,Yoshitake Nishimune,Gene,ELSEVIER SCIENCE BV,Vol. 204,No. 1-2,p. 159-163,1997年12月19日,研究論文(学術雑誌)
  • Tissue-specific knockout of the mouse Pig-a gene reveals important roles for GPI-anchored proteins in skin development,Masahito Tarutani,Satoshi Itami,Masaru Okabe,Masahito Ikawa,Tadashi Tezuka,Kunihiko Yoshikawa,Taroh Kinoshita,Junji Takeda,Proceedings of the National Academy of Sciences of the United States of America,NATL ACAD SCIENCES,Vol. 94,No. 14,p. 7400-7405,1997年07月08日,研究論文(学術雑誌)
  • 'Green mice' as a source of ubiquitous green cells,Masaru Okabe,Masahito Ikawa,Katsuya Kominami,Tomoko Nakanishi,Yoshitake Nishimune,FEBS Letters,ELSEVIER SCIENCE BV,Vol. 407,No. 3,p. 313-319,1997年05月05日,研究論文(学術雑誌)
  • The regulation of membrane cofactor protein (CD46) expression by the 3' untranslated region in transgenic mice,Shuji Miyagawa,Shoki Mikata,Hironori Tanaka,Masahito Ikawa,Katsuya Kominami,Tsukasa Seya,Yoshitake Nishimune,Ryota Shirakura,Masaru Okabe,Biochemical and Biophysical Research Communications,ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS,Vol. 233,No. 3,p. 829-833,1997年04月,研究論文(学術雑誌)
  • Spermatogenesis: Molecular biological approaches,Y Nishimune,M Okabe,H Tanaka,J Tsuchida,M Ikawa,CURRENT ADVANCES IN ANDROLOGY,MONDUZZI EDITORE,Vol. 111-117,p. 111-117,1997年,研究論文(国際会議プロシーディングス)
  • Transcriptional activation of a hybrid promoter composed of cytomegalovirus enhancer and β-actin/β-globin gene in glomerular epithelial cells in vivo,Yoshitaka Akagi,Yoshitaka Isaka,Akiko Akagi,Masahito Ikawa,Masaru Takenaka,Toshiki Moriyama,Atsushi Yamauchi,Masaru Horio,Naohiko Ueda,Masaru Okabe,Enyu Imai,Kidney International,BLACKWELL SCIENCE INC,Vol. 51,No. 4,p. 1265-1269,1997年,研究論文(学術雑誌)
  • The regulation of membrane cofactor protein (CD46) expression in transgenic mice: The importance of the first 125 bp of the 3' untranslated region,S. Miyagawa,M. Ikawa,K. Kominami,H. Tanaka,S. Mikata,H. Matsuda,T. Seya,R. Shirakura,M. Okabe,Transplantation Proceedings,ELSEVIER SCIENCE INC,Vol. 29,No. 1-2,p. 941-942,1997年,研究論文(国際会議プロシーディングス)
  • Glycosylphosphatidylinositol-anchor-deficient mice: Implications for clonal dominance of mutant cells in paroxysmal nocturnal hemoglobinuria,Kazuyoshi Kawagoe,Daisuke Kitamura,Masaru Okabe,Ichiro Taniuchi,Masahito Ikawa,Takeshi Watanabe,Taroh Kinoshita,Junji Takeda,Blood,W B SAUNDERS CO,Vol. 87,No. 9,p. 3600-3606,1996年05月01日,研究論文(学術雑誌)
  • Difference of expression levels between gene technological product ΔCYT- MCP(CD46) and intact MCP(CD46) in transgenic mice,Miyagawa S,Ikawa M,Kominami K,Yoshimura Y,Tanaka H,Mikata S,Shirakura R,Matsuda H,Yanagi Y,Seya T,Okabe M,Transplantation Proceedings,APPLETON & LANGE,Vol. 28,No. 2,p. 585-586,1996年,研究論文(国際会議プロシーディングス)
  • In vitro and in vivo studies to prevent hyperacute rejection,S. Miyagawa,M. Mikata,H. Matsuda,M. Ikawa,M. Okabe,S. Nagasawa,M. Matsumoto,T. Seya,R. Shirakura,Transplantation Proceedings,APPLETON & LANGE,Vol. 28,No. 2,p. 1031-1033,1996年,研究論文(国際会議プロシーディングス)
  • A rapid and non-invasive selection of transgenic embryos before implantation using green fluorescent protein (GFP),Masahito Ikawa,Katsuya Kominami,Yasuhide Yoshimura,Keiichi Tanaka,Yoshitake Nishimune,Masaru Okabe,FEBS Letters,ELSEVIER SCIENCE BV,Vol. 375,No. 1-2,p. 125-128,1995年11月13日,研究論文(学術雑誌)
  • Green fluorescent protein as a marker in transgenic mice,Masahito Ikawa,Katsuya Kominami,Yasuhide Yoshimura,Keiichi Tanaka,Yoshitake Nishimune,Masaru Okabe,Development, Growth &amp; Differentiation,BLACKWELL SCIENCE PUBL AUSTR,Vol. 37,No. 4,p. 455-459,1995年08月,研究論文(学術雑誌)
  • Improvement of Fusing Ability of Human Sperm to Zona-Free Hamster Eggs by Conditioned Media,Masahito Ikawa,Masahito Ikawa,Xing Ying,Keiichi Tanaka,Kazutomo Ohashi,Kazutomo Ohashi,Fumitaka Saji,Masahito Ikawa,Masaru Okabe,Biological and Pharmaceutical Bulletin,PHARMACEUTICAL SOC JAPAN,Vol. 18,No. 1,p. 5-8,1995年,研究論文(学術雑誌)
  • Degeneration of skeletal and cardiac muscles in c-myb transgenic mice (共著),Furuta Y,Aizawa S,Suda Y,Ikawa Y,Nakagoshi H,Nishina Y,Ishii S,Transgenic Research,CHAPMAN HALL LTD,Vol. 2,No. 4,p. 199-207,1993年07月,研究論文(学術雑誌)
  • Homology of an acrosome-reacted sperm-specific antigen to CD46,Masaru Okabe,Xing Ying,Morio Nagira,Masahito Ikawa,Yasuhiro Kohama,Tsutomu Mimura,Keiichi Tanaka,Journal of Pharmacobio-Dynamics,PHARMACEUTICAL SOC JAPAN,Vol. 15,No. 8,p. 455-459,1992年,研究論文(学術雑誌)

MISC

  • Spar1 is a novel transmembrane gene required for acrosome formation in mouse,Julio Castaneda,Yuhkoh Satouh,Darius Devlin,Martin M. Matzuk,Masahito Ikawa,2019年07月
  • Glycerol kinase 2 is important for proper arrangement of crescent-like mitochondria to form the mitochondrial sheath,Keisuke Shimada,Haruhiko Miyata,Masahito Ikawa,2019年07月
  • Deficiency of sperm hyaluronidase affects the male infertility in SPAM1/HYAL5 double mutants,Park Soojin,2019年06月
  • CRISPR/Cas9 Mediated Genome Editing and Its Application for the Study of Fertilization,伊川 正人,2019年05月
  • CRISPR/Cas9 mediated genome editing in mouse zygote and analysis of fertility-related genes,Seiya Oura,Lu yonggang,Nobuyuki Sakurai,Taichi Noda,Masahito Ikawa,2019年05月
  • ゲノム編集技術を用いた精子機能の解析,諸星 茜,宮田 治彦,伊川 正人,谷本学校 毒性質問箱 第20号,No. 20,p. 30-36,2018年09月
  • SPAR1 is a Novel Transmembrane Protein Required for Acrosome Formation in Mice,Julio M,Castaneda,Yuhkoh Satouh,Darius J. Devlin,Martin M. Matzuk,Masahito Ikawa,2018年07月
  • RSPH6A is essential for sperm flagellum formation and male fertility in mice,Haruhiko Miyata,Ferheen Abbasi,Keisuke Shimada,Akane Morohoshi,Kaori Nozawa,Takafumi Matsumura,Masahito Ikawa,2018年07月
  • Human globozoospermia-related gene Spata16 is essential for spermiogenesis in mice,Yoshitaka Fujihara,Asami Oji,Tamara Larasati,Kanako Kojima-Kita,Masahito Ikawa,2017年09月
  • Sperm motility and its competency for mammalian fertilization,Haruhiko Miyata,Masahito Ikawa,2017年07月
  • Gk2 knockout mice show impaired sperm motility and male infertility,Keisuke Shimada,Hirotaka Kato,Haruhiko Miyata,Yuhkoh Satouh,Masahito Ikawa,2017年07月
  • ゲノム編集と生殖工学への応用,Miyata H, Ikawa M,臨床婦人科産科,2017年05月
  • IZUMO1の細胞内領域はマウスの生殖能力に必須ではない,Haruhiko Miyata,Samantha,A.M. Young,Yukoh Satouh,Muto Masanaga,Martin R. Larsen,R. John Aitken,Mark A. Baker,Masahito Ikawa,2017年05月
  • Generation of point mutant mouse model responsible for human globozoospermia by CRISPR/Cas9 system,Yoshitaka Fujihara,Asami Oji,Tamara Larasati,Kanako Kojima-Kita,Masahito Ikawa,2017年05月
  • Knock-down of Tropomyosin 2 created by CRISPR-CAS9 in mouse induces age-related cataract,Eri Kubo,Teppei Shibata,Shinsuke Shibata,Hiroshi Sasaki,Etsuko Kiyokawa,Masato Ikawa,Dhirendra P. Singh,INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE,ASSOC RESEARCH VISION OPHTHALMOLOGY INC,Vol. 57,No. 12,2016年09月,研究発表ペーパー・要旨(国際会議)
  • Functional analysis of Plac1 in placental formation using knockout mice and lentiviral vector-mediated complementation,Masanaga Muto,Yoshitaka Fujihara,Tomohiro Tobita,Daiji Kiyozumi,Masahito Ikawa,2016年02月
  • Sperm-specific calcineurin is necessary for midpiece flexibility and male fertility,Haruhiko Miyata,Yuhkoh Satouh,Daisuke Mashiko,Masanaga Muto,Kaori Nozawa,Kogiku Shiba,Yoshitaka Fujihara,Ayako Isotani,Kazuo Inaba,Masahito Ikawa,2016年02月
  • Erratum: Real-time observation of acrosomal dispersal from mouse sperm using GFP as a marker protein (FEBS Lett. (1999) 449 (277-283)),Tomoko Nakanishi,Masahito Ikawa,Shuichi Yamada,Martti Parvinen,Tadashi Baba,Yoshitake Nishimune,Masaru Okabe,FEBS Letters,ELSEVIER SCIENCE BV,Vol. 589,No. 20,p. 3220-3220,2015年10月07日
  • 精子カルシニューリンはオスの生殖能に必須である,宮田 治彦, 伊川 正人,ライフサイエンス新着論文レビュー,Vol. 67,No. 3,2015年10月
  • TROPHOBLAST SPECIFIC CONDITIONAL ATG7 KNOCKOUT PREGNANT MICE DEVELOP GESTATIONAL HYPERTENSION,Aiko Aoki,Masahito Ikawa,Akitoshi Nakashima,Tamotsu Yoshimori,Shigeru Saito,PLACENTA,W B SAUNDERS CO LTD,Vol. 36,No. 10,p. A13-A13,2015年10月,研究発表ペーパー・要旨(国際会議)
  • PROTON PUMP INHIBITORS QUENCH THE PATHOPHYSIOLOGICAL CHARACTERISTICS OF PREECLAMPSIA IN BOTH HUMAN AND MOUSE MODELS AND REPRESENT AN EXCITING NOVEL CANDIDATE THERAPEUTIC,Kenji Onda,Stephen Tong,Natalie Binder,Sally Beard,Tu'uhevaha Kaitu'u-Lino,Masanaga Muto,Masahito Ikawa,Mark Dilworth,Lewis Renshal,Sevvandi Senadheera,Laura Parry,Roxanne Hastie,Fiona Brownfoot,Laura Tuohey,Kirsten Palmer,Natalie Hannan,PLACENTA,W B SAUNDERS CO LTD,Vol. 36,No. 9,p. A10-A11,2015年09月,研究発表ペーパー・要旨(国際会議)
  • CRISPR/Casシステムを用いた遺伝子改変マウスの作製とその応用,野田大地、伊川正人,生産と技術,Vol. 252,No. 2,2015年07月
  • Ca2+-Dependent Phosphatase and Sperm Motility,Haruhiko Miyata,Yuhkoh Satouh,Daisuke Mashiko,Masanaga Muto,Kaori Nozawa,Kogiku Shiba,Yoshitaka Fujihara,Ayako Isotani,Kazuo Inaba,Masahito Ikawa,2015年07月
  • Analysis of PLAC1 in mouse placental formation by a lentiviral vector,Masanaga Muto,Yoshitaka Fujihara,Masahito Ikawa,2015年06月
  • CRISPR/Cas mediated genome editing in mice,Daisuke Mashiko,Yoshitaka Fujihara,Yuhkoh Satouh,Masahito Ikawa,2015年03月
  • 哺乳類におけるゲノム編集の現状と今後の展望,野田 大地,伊川 正人,脳21,Vol. 3,2015年01月
  • マウス個体でのゲノム編集(2)──簡便かつ迅速な遺伝子改変マウス作製法について,藤原 祥高, 伊川 正人,医学のあゆみ,Vol. 18,No. 1,2015年01月
  • ゲノム編集-基礎から応用へ,伊川 正人,医学のあゆみ,Vol. 252,No. 2,2015年01月
  • Evolution of mammalian viviparity by retrotransposon-derived genes,Ryuichi Ono,Moe Kitazawa,Masahito Ikawa,Tomoko Kaneko-Ishino,Fumitoshi Ishino,GENES & GENETIC SYSTEMS,GENETICS SOC JAPAN,Vol. 89,No. 6,p. 287-287,2014年12月,研究発表ペーパー・要旨(国際会議)
  • ゲノム編集がひらく遺伝子改変マウスの未来,伊川 正人,領域融合レビュー,大学共同利用機関法人 情報・システム研究機構 ライフサイエンス統合データベースセンター,Vol. 3,2014年07月
  • マウスのゲノム編集がもたらす可能性,藤原 祥高, 伊川 正人,実験医学,2014年06月
  • Proteinuria in AMPD2-deficient mice (vol 17, pg 28, 2012),K. Toyama,H. Morisaki,J. Cheng,H. Kawachi,F. Shimizu,M. Ikawa,M. Okabe,T. Morisaki,GENES TO CELLS,WILEY-BLACKWELL,Vol. 19,No. 6,p. 540-540,2014年06月
  • C57BL/6Nを遺伝的背景に持つターゲットトランスジェネシス用種マウスの作製と評価,大塚正人,三浦浩美,磯谷綾子,伊川正人,佐藤正宏,木村穣,日本実験動物学会総会講演要旨集,Vol. 61st,2014年05月01日
  • マウスにおけるCRISPR/Cas9を用いた遺伝子改変,藤原 祥高,伊川 正人,今すぐ始めるゲノム編集 実験医学別冊 最強のステップUPシリーズ,羊土社,p. 95-107,2014年03月
  • 精子と透明帯の相互作用,藤原 祥高,伊川 正人,細胞工学,学研メディカル秀潤社,Vol. 33,No. 4,p. 380-385,2014年03月
  • 受精メカニズム新論争 ドグマの再構築(監修)(Overview),伊川 正人,細胞工学,学研メディカル秀潤社,Vol. 33,No. 4,p. 362-365,2014年03月
  • 精巣内生殖細胞特異的な発現を示すTex101欠損マウスの機能解析,藤原祥高,徳弘圭造,室悠子,荒木慶彦,伊川正人,岡部勝,J Reprod Dev,(一社)日本繁殖生物学会,Vol. 58,No. Suppl Japanese Issue,p. J94-j94,2012年08月
  • The in vivo imaging of fertilizing spermatozoa traveling in female reproductive tract,M. Okabe,Y. Muro,M. Ikawa,JOURNAL OF REPRODUCTIVE IMMUNOLOGY,ELSEVIER IRELAND LTD,Vol. 94,No. 1,p. 101-101,2012年05月,研究発表ペーパー・要旨(国際会議)
  • 精巣内生殖細胞特異的な発現を示すTex101欠損マウスの機能解析,藤原祥高,徳弘圭造,室悠子,荒木慶彦,伊川正人,岡部勝,日本実験動物学会総会講演要旨集,Vol. 59th,2012年05月
  • Preeclamptic model mice and exploration of therapy,Keiichi Kumasawa,Tadashi Kimura,Masaru Okabe,Masahito Ikawa,PLACENTA,W B SAUNDERS CO LTD,Vol. 32,No. 9,p. A162-A162,2011年09月,研究発表ペーパー・要旨(国際会議)
  • 精巣内生殖細胞特異的な発現を示すTex101ノックアウトマウスの作製と機能解析,藤原祥高,徳弘圭造,室悠子,荒木慶彦,伊川正人,岡部勝,日本分子生物学会年会プログラム・要旨集(Web),Vol. 34th,2011年
  • 骨格筋特異的プロモーター活性の詳細な検討,小出達也,木村円,内野克尚,菅智宏,伊川正人,山下賢,前田寧,CHAMBERLAIN Jeffrey,HAUSCHKA Stephen,内野誠,日本神経学会学術大会プログラム・抄録集,Vol. 52nd,2011年
  • 筋ジストロフィーに対するトランスレーショナル・リサーチ ウイルスベクターと間葉系幹細胞を用いた筋ジストロフィーの治療研究―骨格筋特異的プロモーター活性の詳細な検討―,内野誠,小出達也,木村円,内野克尚,菅智宏,山下賢,前田寧,伊川正人,CHAMBERLAIN Jeffrey S,HAUSCHKA Stephen D,精神・神経疾患研究開発費による研究報告集(2年度班・初年度班) 平成22年度,p. 242-243,2011年
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  • Significance of feto-maternal interface in mice model: from implantation failure to pre-eclampsia,T. Kimura,K. I. Kumasawa,H. Nakamura,M. Okabe,M. Ikawa,AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY,WILEY-BLACKWELL PUBLISHING, INC,Vol. 64,p. 8-9,2010年12月,研究発表ペーパー・要旨(国際会議)
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  • How far was fertilization elucidated?,Naokazu Inoue,Ryo Yamaguchi,Masahito Ikawa,Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme,Vol. 50,No. 11,p. 1405-1412,2005年09月,書評論文,書評,文献紹介等
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著書

  • 学術書,実験医学別冊 完全版 ゲノム編集実験スタンダード Ⅱ実践編 (15) gRNA/Cas9複合体を用いたマウスでのゲノム編集,野田 大地,大浦 聖矢,伊川 正人,(株)羊土社,ISBN:9784758122443,2019年12月
  • 学術書,「マウスでのゲノム編集」 実験医学増刊 Vol.34 No.20 All Aboutゲノム編集,野田 大地,大字 亜沙美,伊川 正人,(株)羊土社,ISBN:9784758103596,2016年12月
  • 学術書,実験医学別冊マウス表現型解析スタンダード 第4章(8) 生殖不全の表現型解析,藤原祥高,佐藤裕公,伊川正人,羊土社,ISBN:9784758101981,2016年11月
  • 学術書,「 生殖不全の表現型解析」 実験医学別冊 マウス表現型解析スタンダード,藤原 祥高,佐藤 裕公,伊川 正人,(株)羊土社,2016年11月
  • 学術書,「ゲノム編集技術を使った遺伝子改変マウスの作製」 実験医学別冊 マウス表現型解析スタンダード,野田 大地,大字 亜沙美,伊川 正人,(株)羊土社,2016年11月
  • 学術書,「精子カルシニューリンが受精能力に必要」 医学のあゆみ Vol. 258 No. 9,宮田 治彦,伊川 正人,医歯薬出版株式会社,2016年08月
  • 学術書,「精子カルシニューリンが受精能力に必要」 医学のあゆみ Vol. 258 No. 9,宮田 治彦,伊川 正人,医歯薬出版株式会社,2016年08月
  • 学術書,「精子カルシニューリンはオスの生殖能に必須である」 臨床免疫・アレルギー科 Vol. 66 No. 1,宮田 治彦,伊川 正人,(有)科学評論社,2016年07月
  • 学術書,「精子カルシニューリンはオスの生殖能に必須である」 臨床免疫・アレルギー科 Vol. 66 No. 1,宮田 治彦,伊川 正人,(有)科学評論社,2016年07月
  • 学術書,「マウスの生殖能力に必須な精子カルシニューリンは男性避妊薬の標的となりうる」Japanese Scientists in Science 2015,宮田 治彦,伊川 正人,American Association for the Advancement of Science(AAAS),2016年06月
  • 学術書,「ゲノム編集・遺伝子改変技術と生殖医学」 HORMONE FRONTIER IN GYNECOLOGY 2016.6 Vol.23 No.2,伊川 正人,(株)メディカルレビュー社,2016年06月
  • 学術書,「マウスの生殖能力に必須な精子カルシニューリンは男性避妊薬の標的となりうる」Japanese Scientists in Science 2015,宮田 治彦,伊川 正人,American Association for the Advancement of Science(AAAS),2016年06月
  • 学術書,「ゲノム編集・遺伝子改変技術と生殖医学」 HORMONE FRONTIER IN GYNECOLOGY 2016.6 Vol.23 No.2,伊川 正人,(株)メディカルレビュー社,2016年06月
  • 学術書,「カルシニューリンは精子中片部の屈曲能とオスの生殖能に必須である」細胞工学 2016年3月号,宮田 治彦,伊川 正人,(株)学研メディカル秀潤社,ISBN:9784780901764,2016年02月
  • 学術書,「マウスの生殖能力に必須な精子カルシニューリンは男性避妊薬の標的となりうる」実験医学 2016年3月号 病態を再現・解明し、創薬へとつなぐ 疾患iPS細胞,宮田 治彦,伊川 正人,(株)羊土社,ISBN:9784758101493,2016年02月
  • 学術書,「カルシニューリンは精子中片部の屈曲能とオスの生殖能に必須である」細胞工学 2016年3月号,宮田 治彦,伊川 正人,(株)学研メディカル秀潤社,ISBN:9784780901764,2016年02月
  • 学術書,「マウスの生殖能力に必須な精子カルシニューリンは男性避妊薬の標的となりうる」実験医学 2016年3月号 病態を再現・解明し、創薬へとつなぐ 疾患iPS細胞,宮田 治彦,伊川 正人,(株)羊土社,ISBN:9784758101493,2016年02月
  • 学術書,論文だけではわからない ゲノム編集成功の秘訣Q&A 第3章 マウスでのゲノム編集,藤原 祥高,伊川正人,(株)羊土社,ISBN:9784758101936,2015年11月
  • 学術書,植物でのゲノム編集、実験医学別冊 ゲノム編集実験Q&A,安本周平,關 光,村中俊哉,羊土社,ISBN:9784758101936,2015年11月
  • 学術書,論文だけではわからない ゲノム編集成功の秘訣Q&A 第3章 マウスでのゲノム編集,藤原 祥高,伊川正人,羊土社,ISBN:9784758101936,2015年11月
  • 学術書,人工ヌクレアーゼを用いた植物代謝工学、進化するゲノム編集技術,安本周平,關 光,村中俊哉,エヌ・ティー・エス,ISBN:9784860434359,2015年10月
  • 学術書,進化するゲノム編集技術,宮田治彦,伊川正人,(株)エヌ・ティー・エス,ISBN:9784860434359,2015年10月
  • 学術書,医学のあゆみ ゲノム編集 -基礎から応用へ マウス個体でのゲノム編集(2)──簡便かつ迅速な遺伝子改変マウス作製法について,藤原祥高,伊川正人,医歯薬出版株式会社,2015年01月
  • 学術書,Targeted Genome Editing Using Site-Specific Nucleases,Samantha A,M. Young,Mark Baker,Masahito Ikawa,Springer Japan,ISBN:9784431552260,2014年10月
  • 学術書,実験医学 ゲノム編集法の新常識!CRISPR/Casが生命科学を加速する マウスのゲノム編集がもたらす可能性,藤原祥高,伊川正人,羊土社,ISBN:9784758101295,2014年06月
  • 学術書,今すぐ始めるゲノム編集 実験医学別冊 最強のステップUPシリーズ マウスにおけるCRISPR/Cas9を用いた遺伝子改変,藤原祥高,伊川正人,羊土社,ISBN:9784758101905,2014年03月
  • 学術書,細胞工学 受精メカニズム新論争ドグマの再構築 精子と透明帯の相互作用,藤原祥高,伊川正人,秀潤社,2014年03月
  • 学術書,論文ができてしまう! 疾患モデルマウス表現型解析指南 生殖細胞・不妊,藤原祥高,伊川正人,中山書店,ISBN:9784521734491,2011年12月
  • 学術書,モデル動物利用マニュアル生物機能モデルと新しいリソース・リサーチツール ノックアウトマウスプロジェクト,森岡裕香,藤原祥高,伊川正人,エル・アイ・シー,ISBN:9784900487482,2011年02月
  • Green fluorescent protein (GFP) as a vital marlcer in mammals(共著),Cuor Top. Dev Biol,1999年

特許・実用新案・意匠

  • 栄養外胚葉細胞特異的遺伝子導入法,岡部勝,伊川正人,特許第5020083号,特願2007-530936,出願日:2006年07月,登録日:2012年06月

受賞

  • 安東・田嶋賞,伊川正人,日本実験動物学会,2021年05月
  • SSR Research Award,伊川 正人,米国生殖生物学会,2017年07月
  • 総長顕彰 研究部門,伊川正人,大阪大学,2014年07月
  • 日本学術振興会賞,伊川 正人,日本学術振興会,2013年02月
  • 奨励賞,伊川正人,日本実験動物学会,1999年05月
  • 業績報告会・最優秀学術賞,伊川正人,大阪大学・微生物病研究所,1998年01月
  • DGD Wiley Blackwell Prize 2015,Daisuke Mashiko,Samantha A Young,Masanaga Muto,Hirotaka Kato,Kaori Nozawa,Masaki Ogawa,Taichi Noda,Yeon-Joo Kim,Yuhkoh Satouh,Yoshitaka Fujihara,Masahito Ikawa,日本発生生物学会,2015年06月

講演・口頭発表等

  • ゲノム編集と受精研究への応用,伊川 正人,第17回熊本大学生命資源・研究センターシンポジウム,2021年03月
  • マウスDRC7は精子鞭毛形成およびオス妊孕性に必須である,諸星 茜,⽇本アンドロロジー学会 第39回学術⼤会,2021年01月
  • ルミクリンシステムによる精子成熟の制御メカニズム,伊川 正人,配偶子インテグリティの構築』『全能性プログラム』合同公開シンポジウム2020,2020年12月
  • 精巣上体上皮細胞の分化に影響する神経ペプチド様遺伝子の機能解析,島田 健太郎,第43回日本分子生物学会年会,2020年12月
  • CRISPR/Cas9 Mediated Genome Editing and Its Application for the Study of Fertilization in Mice,伊川 正人,The University of Kansas Medical Center seminar,2020年11月
  • 遺伝子改変マウスを用いた精子鞭毛形成の解析,諸星 茜,第7回生殖若手の会,2020年10月
  • ゲノム編集マウスが切り開く受精研究の最前線,伊川 正人,第38回日本受精着床学会総会・学術講演会,2020年10月
  • ゲノム編集マウスが切り開く受精研究の最前線,伊川 正人,第113回日本繁殖生物学会大会,2020年09月
  • CRISPR/Cas9-mediated genome-edited mice reveal 10 testis-enriched genes are dispensable for male fecundity,Soojin Park,SSR Virtual,2020年07月
  • 最新の方法と将来の展望 ①ゲノム編集技術と遺伝子改変動物の作成,伊川 正人,第84回日本循環器学会学術集会,2020年07月
  • ゲノム編集を利用した遺伝子治療および最先端ゲノム編集技術とその安全性,伊川 正人,第47回日本毒性学会学術年会,2020年06月

報道

  • 精子の成熟 たんぱく質特定 阪大など 不妊治療へ応用期待,読売新聞 朝刊 2020年7月3日,2020年07月
  • 精子成熟の鍵を発見 男性不妊の解明に一歩 大阪大など,朝日新聞DIGITAL,2020年06月
  • 精子成熟 仕組み解明,毎日新聞 夕刊 (2020.06.05),2020年06月
  • 精子受精能力、獲得促すたんぱく質 阪大グループ発見 男性不妊症の究明糸口に,毎日新聞 大阪夕刊 2020年6月8日,2020年06月
  • 大阪大とBaylor医科大、精子の成熟を制御する仕組みをScience誌にて発表,日経バイオテク 2020年6月10日,2020年06月
  • ⼤阪⼤とBaylor医科⼤、精⼦と卵の融合に必須な精⼦の膜蛋⽩質をCRISPRで相次ぎ特定,日経バイオテク,2020年05月
  • サラヤ、阪大の微生物病研究所と共同研究契約締結-欧州標準試験法による新型コロナウイルス病原体を用いた有効性評価試験開始,日本経済新聞(ネット記事),2020年05月
  • 受精に必須な精子遺伝子発見,朝日新聞,2020年04月
  • 精子が「電気信号」を感じる独自のメカニズム、大阪大学が発見,大学ジャーナルオンライン,2019年12月
  • 宇宙滞在マウス、精子は正常 特製ケージが生還のカギに,朝日新聞デジタル,2019年10月
  • 宇宙生活 生殖影響なし,大分合同新聞(一面),2019年09月
  • 宇宙からマウス生還に成功,ABCテレビ,2019年09月
  • 宇宙からマウス無事生還 繁殖能力影響なし,読売テレビ,2019年09月
  • ISSで1か月飼育 マウス精子異常なし,ヨミダス歴史館 読売新聞,2019年09月
  • 宇宙滞在、生殖に影響せず,日本経済新聞社,2019年09月
  • 宇宙に滞在しても生殖力に影響なし,毎日新聞朝刊,2019年09月
  • 精子の受精能力に関与 阪大 関連遺伝子群突き止め,日本経済新聞 夕刊,2019年08月
  • 精子の受精能力を制御する遺伝子群 阪大が発見,日本経済新聞(web),2019年08月
  • 受精に必要な遺伝子群を発見-男性不妊治療などへの応用も期待-,読売テレビ,2019年08月
  • 精子受精 遺伝子群が関与,読売新聞,2019年08月
  • 不妊に関わる精子の遺伝子群、マウスで発見 阪大など,朝日新聞DIGITAL,2019年08月
  • ゲノム編集 ヒトの病気再現,朝日新聞,2017年03月
  • 国際宇宙ステーション・「きぼう」における、長期飼育マウスの全数生存帰還の世界初の達成ならびに次世代仔マウスの誕生について,JAXAウェブサイト,2016年10月
  • 「宇宙マウス」の精子から子誕生,日本経済新聞,2016年10月
  • 「宇宙マウス」2世誕生=大西さん飼育、帰還後に―JAXA,YAHOO!JAPANニュース,2016年10月
  • 東大の濡木教授と阪大の伊川教授ら、精子IZUMO1への結合で重要な卵子JUNOのアミノ酸残基を特定 CRISPRで作成したJUNO欠損マウスの卵子で新実験系を確立,日経バイオテク,2016年07月
  • 受精の仕組み解明に新手法 卵子の細胞膜タンパク質構造決定,科学新聞,2016年07月
  • 精巣で多く発現する遺伝子なのに約7割が生殖能力に関係なし,科学新聞,2016年07月
  • Inhibiting Sperm Protein Causes Infertility,The Scientist Magazine®,2015年10月
  • Sperm-specific mechanism could lead to male contraceptive,Science HP,2015年10月
  • Another Step Closer to Male Birth Control Pills A protein might lead to an oral contraceptive for men,Smithsonian,2015年10月
  • Scientists make male pill breakthrough -but it's still 'years' away,Telegraph,2015年10月
  • Mouse Study Hints at New 'Male Contraceptive',The Philly,2015年10月
  • Scientists report new avenue for study of male infertility, contraception,The Japan Times,2015年10月
  • Altering how sperm develop could lead to a reversible male birth control,The Verge,2015年10月
  • Human sperm compete to fertilize an egg. A study published in Science this week hints at a new, reversible means of blocking male fertility.,The Why Files,2015年10月
  • OSAKA, Japan, Oct. 2 (UPI) -- Researchers in Japan may have found a method for reliable, reversible male contraception by blocking a protein in mice using two,UPI,2015年10月
  • 男性避妊薬の開発に新たな手掛かり/日本の研究者ら、マウスの精子カルシニューリン機能を阻害,今朝の日本関係記事inドイツ,2015年10月
  • Male Birth Control Treatment Could Focus on Sperm Proteins, Not Hormones,Richard Dawkins Foundation,2015年10月
  • Researchers identify new molecular target for male contraceptives,Pharma Business International,2015年10月
  • Newly Identified Sperm-Specific Protein Bolsters Prospects Of Male Contraceptive,IFLScience,2015年10月
  • Potential Male Birth Control Pill Is Found in an Immunosuppressant Drug,Newsweek,2015年10月
  • Scientists find way to cause temporary infertility in mice, could lead to first birth control pill for men: report,NY Daily News,2015年10月
  • Mouse Study Hints at New 'Male Contraceptive',NIH_ MedlinePlus,2015年10月
  • En busca de la pildora anticonceptiva masculina,Materia Spanish,2015年10月
  • Scientists identify potential control ‘pill‘ for men,LA times1,2015年10月
  • EQUALITY OF CONTRACEPTION: SCIENTISTS MAY HAVE FINALLY FOUND A WAY TO MAKE THE ‘MALE PILL’,INQUISITR,2015年10月
  • Mouse Study Hints at New 'Male Contraceptive',HealthDay,2015年10月
  • Scientists come a step closer to creating the world's first male contraceptive pill -but there's a strong chance the pharma industry won't be thrilled,City A.M.,2015年10月
  • Breakthrough in male contraceptive pill but drug only lasts days (and most women wouldn't trust men to take it anyway),Daily Mail Online,2015年10月
  • Japanese researchers may be onto male birth control pill breakthrough,Boston Herald,2015年10月
  • 男性避妊薬開発に繋がる標的分子をマウスで発見,科学新聞,2015年10月
  • 阪大など、精子の活動に不可欠な酵素を発見ー不妊治療、男性避妊薬への応用も,テックタイムズ,2015年10月
  • 阪大の伊川教授ら、精巣特異的カルシニョーリンが男性避妊薬の標的に、Scienceで発表,日経バイオテク,2015年10月
  • 精子正常運動に酵素不可=不妊解明へ前進-阪大,時事通信社・時事ドットコム・WSJ・msn・YAHOO!JAPANニュース,2015年10月
  • 精子動かす物質特定、大阪大など 不妊症解明に期待,信濃毎日新聞・静岡新聞・大分合同新聞・中國新聞・長崎新聞・東京新聞・福島民友新聞社,2015年10月
  • 精子動かす物質特定、大阪大など 不妊症解明に期待,デーリー東北・ロイター・河北新報・京都新聞・高知新聞・佐賀新聞・四国新聞社,2015年10月
  • 精力そのまま男性用ピル 酵素を弱め・・・阪大が突き止め 不妊症究明・治療に新手法,産経ニュース・産経WEST,2015年10月
  • 男性避妊薬の標的分子 阪大発見、マウスで実験,日経産業新聞,2015年10月
  • 精子の活動に欠かせぬ酵素,日本經濟新聞,2015年10月
  • 男性用避妊薬の開発に道 精子の動き「スイッチ役」酵素確認,朝日新聞,2015年10月
  • 不妊 男性の原因遺伝子特定,読売新聞,2012年02月
  • 受精の酵素発見 「不妊治療に"光"」,産経新聞,2012年02月
  • 男性不妊の原因酵素 「阪大、マウス実験で特定」,日本経済新聞,2012年02月
  • 男性不妊症 解明に光 「受精へ必須酵素 マウスで確認」,毎日新聞,2012年02月
  • 妊娠高血圧マウス作成,毎日新聞,2010年12月
  • 妊婦OKの薬へ前進,朝日新聞,2010年12月
  • 妊娠中毒症治療,日経新聞,2010年12月
  • 妊娠高血圧症に新治療法,産経新聞,2010年12月
  • Study reverses male infertility in mice,CNN,2002年05月
  • 緑色発光ネズミ誕生,日本経済新聞,1997年06月

学術貢献

  • 日本生殖免疫学会(理事),2021年01月 ~ 継続中
  • NPO法人 発生工学研究会(理事長),2012年11月 ~ 継続中
  • 日本ゲノム編集学会(理事),2020年 ~ 2022年
  • 日本実験動物学会(理事),2012年05月 ~ 2018年05月
  • 米国生殖生物学会2019プログラム委員長,2019年 ~
  • 日本実験動物学会(評議員),2006年05月 ~ 継続中
  • 米国生殖生物学会(プログラム委員),2012年07月 ~ 2014年07月
  • LASセミナー3 賢く使おうリソース・インフラ,日本実験動物学会,2019年05月 ~
  • BDR Seminar in Kobe,理化学研究所 生命機能科学研究センター,2018年10月 ~
  • 科学技術振興機構 国際科学技術共同研究推進事業 戦略的国際共同研究プログラム:日本―中国共同研究,2018年04月 ~
  • 生化学若い研究者の会 九州支部 夏のセミナー,生化若手の会 九州支部,2017年08月 ~
  • 通年講座「ラスタ教養大学」伊丹市立生涯学習センター,伊丹市,2017年06月 ~
  • 3領域合同若手勉強会2017,3つの領域グループでの共催,2017年06月 ~
  • Lecture Series from Osaka University, Japan,Institut Teknologi Bandung,2016年01月 ~
  • 第7回遺伝子組換え実験安全研修会 ~ゲノム編集技術の進展と課題~,全国大学等遺伝子研究支援施設連絡協議会,2015年08月 ~
  • 千里ライフサイエンス振興財団・技術講習会,千里ライフサイエンス振興財団,2014年06月 ~

社会貢献

  • 高校生のためのサマースクール@微研 「遺伝子改変技術」を知る・見る・考える,微生物病研究所,2018年08月 ~
  • 第48回大阪大学公開講座,大阪大学企画部男女協働推進・社学連携課,2016年12月 ~
  • サイエンスカフェ@待兼山,大阪大学総合学術博物館,2014年12月 ~