Identification of 2 Novel Species, Mycobacterium novusgordonae and M. shingordonae.

Kazuki Hashimoto, Yuko Abe, Kiyoharu Fukushima, Yuki Matsumoto, Haruko Saito, Yuri Akamine, Takayuki Niitsu, June Yamauchi, Tadayoshi Nitta, Michio Tanaka, Takuro Nii, Takanori Matsuki, Daisuke Motooka, Kazuyuki Tsujino, Keisuke Miki, Kozo Morimoto, Atsushi Kumanogoh, Shizuo Akira, Shota Nakamura, Hiroshi Kida

Emerging infectious diseases　Vol. 31　No. 3　p. 624-627　2025年3月　研究論文（学術雑誌）

Identification of α-galactosylceramide as an endogenous mammalian antigen for iNKT cells.

Yuki Hosono, Noriyuki Tomiyasu, Hayato Kasai, Eri Ishikawa, Masatomo Takahashi, Akihiro Imamura, Hideharu Ishida, Federica Compostella, Hiroshi Kida, Atsushi Kumanogoh, Takeshi Bamba, Yoshihiro Izumi, Sho Yamasaki

The Journal of experimental medicine　Vol. 222　No. 2　2025年2月3日　研究論文（学術雑誌）

Enhancing the efficacy of near-infrared photoimmunotherapy through intratumoural delivery of CD44–targeting antibody–photoabsorber conjugates

Yuichi Adachi, Kotaro Miyake, Kika Ohira, Shingo Satoh, Kentaro Masuhiro, Ryuya Edahiro, Yuya Shirai, Maiko Naito, Yujiro Naito, Takayuki Shiroyama, Shohei Koyama, Haruhiko Hirata, Kota Iwahori, Izumi Nagatomo, Yoshito Takeda, Atsushi Kumanogoh

eBioMedicine　Vol. 112　p. 105566-105566　2025年2月　研究論文（学術雑誌）

Peripheral Neuropathy in Systemic Sclerosis with Proximal Nerve Involvement: Diagnostic Challenges and Response to Corticosteroid Therapy.

Takehiro Suzuki, Takahiro Kawasaki, Goichi Beck, Noyuri Takenaka, Kotaro Ogawa, Eri Itotagawa, Kazuki Matsukawa, Michiko Ohashi, Takeshi Kaneko, Eri Oguro-Igashira, Yumiko Mizuno, Mayuko Izumi, Kohei Tsujimoto, Yasutaka Okita, Takayoshi Morita, Akane Watanabe, Yasuhiro Kato, Masayuki Nishide, Sumiyuki Nishida, Yoshihito Shima, Masashi Narazaki, Atsushi Kumanogoh

Modern rheumatology case reports　2025年1月30日　研究論文（学術雑誌）

Peripheral Neuropathy in Systemic Sclerosis with Proximal Nerve Involvement: Diagnostic Challenges and Response to Corticosteroid Therapy

Takehiro Suzuki, Takahiro Kawasaki, Goichi Beck, Noyuri Takenaka, Kotaro Ogawa, Eri Itotagawa, Kazuki Matsukawa, Michiko Ohashi, Takeshi Kaneko, Eri Oguro-Igashira, Yumiko Mizuno, Mayuko Izumi, Kohei Tsujimoto, Yasutaka Okita, Takayoshi Morita, Akane Watanabe, Yasuhiro Kato, Masayuki Nishide, Sumiyuki Nishida, Yoshihito Shima, Masashi Narazaki, Atsushi Kumanogoh

Modern Rheumatology Case Reports　2025年1月30日　研究論文（学術雑誌）

NHERF2 as a Novel Biomarker for Distinguishing MAC Pulmonary Disease from Tuberculosis Based on Proteome Analysis of Serum Extracellular Vesicles

Maiko Naito, Yoshito Takeda, Ryuya Edahiro, Yuya Shirai, Takatoshi Enomoto, Mana Nakayama, Satoshi Nojima, Mari Nogami-Ito, Masahide Mori, Yukihiro Yano, Takanori Matsuki, Hanako Yoshimura, Reina Hara, Makoto Yamamoto, Kentaro Masuhiro, Yujiro Naito, Shohei Koyama, Kota Iwahori, Izumi Nagatomo, Takayuki Shiroyama, Kotaro Miyake, Haruhiko Hirata, Hiroaki Hase, Kazutake Tsujikawa, Koji Ueda, Atsushi Kumanogoh

International Journal of Molecular Sciences　Vol. 26　No. 3　p. 1155-1155　2025年1月29日　研究論文（学術雑誌）

Intestinal Foxl1+ cell-derived CXCL12 maintains epithelial homeostasis by modulating cellular metabolism.

Mayu Yagita-Sakamaki, Takayoshi Ito, Taiki Sakaguchi, Shuichi Shimma, Bo Li, Daisuke Okuzaki, Daisuke Motooka, Shota Nakamura, Koji Hase, Eiichiro Fukusaki, Akira Kikuchi, Takashi Nagasawa, Atsushi Kumanogoh, Kiyoshi Takeda, Hisako Kayama

International immunology　2025年1月8日　研究論文（学術雑誌）

CAR-NK cells derived from cord blood originate mainly from CD56⁻CD7⁺CD34⁻HLA-DR⁻Lin⁻ NK progenitor cells

Tansri Wibowo, Yosuke Kogue, Shunya Ikeda, Moto Yaga, Mana Tachikawa, Makiko Suga, Shuhei Kida, Kumi Shibata, Kazuhito Tsutsumi, Hiraku Murakami, Yasutaka Ueda, Hisashi Kato, Kentaro Fukushima, Jiro Fujita, Tomoaki Ueda, Shinsuke Kusakabe, Akihisa Hino, Michiko Ichii, Chihaya Imai, Daisuke Okuzaki, Atsushi Kumanogoh, Naoki Hosen

Molecular Therapy Methods and Clinical Development　Vol. 32　No. 4　2024年12月12日　研究論文（学術雑誌）

Variability in non-tumor areas of colorectal cancer patients as revealed by endoscopic intestinal step biopsies.

Shoko Ikuta, Yutaka Saito, So Takata, Yoichiro Nakatani, Izumi Nagatomo, Satoshi Shiba, Yoshito Takeda, Yasushi Totoki, Sayaka Mizutani, Hironori Sunakawa, Hiroaki Ikematsu, Hiroyuki Takamaru, Atsushi Kumanogoh, Shinichi Yachida

Molecular cancer　Vol. 23　No. 1　p. 249-249　2024年11月7日　研究論文（学術雑誌）

The pyruvate-GPR31 axis promotes transepithelial dendrite formation in human intestinal dendritic cells.

Eri Oguro-Igashira, Mari Murakami, Ryota Mori, Ryuichi Kuwahara, Takako Kihara, Masaharu Kohara, Makoto Fujiwara, Daisuke Motooka, Daisuke Okuzaki, Mitsuru Arase, Hironobu Toyota, Siyun Peng, Takayuki Ogino, Yasuji Kitabatake, Eiichi Morii, Seiichi Hirota, Hiroki Ikeuchi, Eiji Umemoto, Atsushi Kumanogoh, Kiyoshi Takeda

Proceedings of the National Academy of Sciences of the United States of America　Vol. 121　No. 44　2024年10月29日　研究論文（学術雑誌）

Case report: Avacopan‐induced severe liver injury with prolonged jaundice and lipoprotein X‐induced dyslipidemia

Yoshiyuki Kioi, Eri Itotagawa, Yusuke Kawachi, Rumiko Ichikawa, Yoshinari Obata, Kohei Tsujimoto, Takahiro Kawasaki, Taro Akira, Kazuma Kosaka, Jeonghoon Park, Masashi Narazaki, Iichiro Shimomura, Atsushi Kumanogoh

International Journal of Rheumatic Diseases　Vol. 27　No. 11　2024年10月28日　研究論文（学術雑誌）

MicroRNA-130a-3p regulates osimertinib resistance by targeting runt-related transcription factor 3 in lung adenocarcinoma.

Takuya Shintani, Yu-Ting Shun, Yuji Toyozumi, Kenji Ikemura, Takayuki Shiroyama, Izumi Nagatomo, Kentaro Jingushi, Yoshito Takeda, Atsushi Kumanogoh, Masahiro Okuda

Scientific reports　Vol. 14　No. 1　p. 24429-24429　2024年10月18日　研究論文（学術雑誌）

Variability of macrolide-resistant profile in Mycobacterium avium complex pulmonary disease.

Kiyoharu Fukushima, Yuki Matsumoto, Yuko Abe, Kazuki Hashimoto, Daisuke Motooka, Seigo Kitada, Haruko Saito, Sho Komukai, Eriko Fukui, Takayuki Niitsu, Hiroshi Nabeshima, Yasuharu Nagahama, June Yamauchi, Tadayoshi Nitta, Takuro Nii, Takanori Matsuki, Kazuyuki Tsujino, Keisuke Miki, Yasushi Shintani, Atsushi Kumanogoh, Shizuo Akira, Shota Nakamura, Hiroshi Kida

Antimicrobial agents and chemotherapy　2024年10月8日　研究論文（学術雑誌）

Proteomics of blood extracellular vesicles in inflammatory respiratory diseases for biomarker discovery and new insights into pathophysiology.

Takahiro Kawasaki, Yoshito Takeda, Atsushi Kumanogoh

Inflammation and regeneration　Vol. 44　No. 1　p. 38-38　2024年9月18日　研究論文（学術雑誌）

Clonal landscape of autoantibody-secreting plasmablasts in COVID-19 patients

Shuhei Sakakibara, Yu-Chen Liu, Masakazu Ishikawa, Ryuya Edahiro, Yuya Shirai, Soichiro Haruna, Marwa Ali El Hussien, Zichang Xu, Songling Li, Yuta Yamaguchi, Teruaki Murakami, Takayoshi Morita, Yasuhiro Kato, Haruhiko Hirata, Yoshito Takeda, Fuminori Sugihara, Yoko Naito, Daisuke Motooka, Chao-Yuan Tsai, Chikako Ono, Yoshiharu Matsuura, James B Wing, Hisatake Matsumoto, Hiroshi Ogura, Masato Okada, Atsushi Kumanogoh, Yukinari Okada, Daron M Standley, Hitoshi Kikutani, Daisuke Okuzaki

Life Science Alliance　Vol. 7　No. 12　p. e202402774-e202402774　2024年9月17日　研究論文（学術雑誌）

Safety, pharmacokinetics, biomarker response and efficacy of E6742: a dual antagonist of Toll-like receptors 7 and 8, in a first in patient, randomised, double-blind, phase I/II study in systemic lupus erythematosus.

Yoshiya Tanaka, Atsushi Kumanogoh, Tatsuya Atsumi, Tomonori Ishii, Fumitoshi Tago, Mari Aoki, Shintaro Yamamuro, Shizuo Akira

RMD open　Vol. 10　No. 3　2024年9月17日　研究論文（学術雑誌）

Neoself-antigens are the primary target for autoreactive T cells in human lupus.

Shunsuke Mori, Masako Kohyama, Yoshiaki Yasumizu, Asa Tada, Kaito Tanzawa, Tatsuya Shishido, Kazuki Kishida, Hui Jin, Masayuki Nishide, Shoji Kawada, Daisuke Motooka, Daisuke Okuzaki, Ryota Naito, Wataru Nakai, Teru Kanda, Takayuki Murata, Chikashi Terao, Koichiro Ohmura, Noriko Arase, Tomohiro Kurosaki, Manabu Fujimoto, Tadahiro Suenaga, Atsushi Kumanogoh, Shimon Sakaguchi, Yoshihiro Ogawa, Hisashi Arase

Cell　2024年9月11日　研究論文（学術雑誌）

Large-scale cross-trait genetic analysis highlights shared genetic backgrounds of autoimmune diseases

Yuji Yamamoto, Yuya Shirai, Ryuya Edahiro, Atsushi Kumanogoh, Yukinori Okada

Immunological Medicine　p. 1-10　2024年8月22日　研究論文（学術雑誌）

CD98 heavy chain protein is overexpressed in non-small cell lung cancer and is a potential target for CAR T-cell therapy.

Moto Yaga, Kana Hasegawa, Shunya Ikeda, Miwa Matsubara, Takashi Hiroshima, Toru Kimura, Yuya Shirai, Wibowo Tansri, Hirofumi Uehara, Mana Tachikawa, Yuzuru Okairi, Masayuki Sone, Hiromi Mori, Yosuke Kogue, Hiroki Akamine, Daisuke Okuzaki, Kotaro Kawagishi, Satoshi Kawanaka, Hiroyuki Yamato, Yukiyasu Takeuchi, Eiji Okura, Ryu Kanzaki, Jiro Okami, Itsuko Nakamichi, Shigeru Nakane, Aki Kobayashi, Takashi Iwazawa, Toshiteru Tokunaga, Hideoki Yokouchi, Yukihiro Yano, Junji Uchida, Masahide Mori, Kiyoshi Komuta, Tetsuro Tachi, Hideki Kuroda, Noriyuki Kijima, Haruhiko Kishima, Michiko Ichii, Shinji Futami, Yujiro Naito, Takayuki Shiroyama, Kotaro Miyake, Shohei Koyama, Haruhiko Hirata, Yoshito Takeda, Soichiro Funaki, Yasushi Shintani, Atsushi Kumanogoh, Naoki Hosen

Scientific reports　Vol. 14　No. 1　p. 17917-17917　2024年8月2日　研究論文（学術雑誌）

ケラチノサイトにおけるSemaphorin 4A発現低下は乾癬非病変部の病態形成に関わる

久米 美輝, 吉岡 華子, 金田 眞理, 熊ノ郷 淳, 藤本 学, 渡邉 玲

日本臨床免疫学会総会プログラム・抄録集　Vol. 52回　p. 80-80　2024年8月

【ヒト疾患と免疫細胞サブセット 解像度をあげて見えてきた病態を規定する疾患のキープレーヤーと治療戦略】(第4章)疾患とのかかわり ANCA関連血管炎に特徴的な単球細胞集団の発見

西出 真之, 熊ノ郷 淳

実験医学　Vol. 42　No. 12　p. 1951-1956　2024年8月

Risk Stratification According to Baseline and Early Change in Neutrophil-to-Lymphocyte Ratio in Advanced Non-Small Cell Lung Cancer Treated with Chemoimmunotherapy: A Multicenter Real-World Study.

Kinnosuke Matsumoto, Yuji Yamamoto, Takayuki Shiroyama, Tomoki Kuge, Masahide Mori, Motohiro Tamiya, Yuhei Kinehara, Akihiro Tamiya, Hidekazu Suzuki, Satoshi Tobita, Kiyonobu Ueno, Toshie Niki, Izumi Nagatomo, Yoshito Takeda, Atsushi Kumanogoh

Targeted oncology　2024年7月11日　研究論文（学術雑誌）

Quantification of escape from X chromosome inactivation with single-cell omics data reveals heterogeneity across cell types and tissues

Yoshihiko Tomofuji, Ryuya Edahiro, Kyuto Sonehara, Yuya Shirai, Kian Hong Kock, Qingbo S. Wang, Shinichi Namba, Jonathan Moody, Yoshinari Ando, Akari Suzuki, Tomohiro Yata, Kotaro Ogawa, Tatsuhiko Naito, Ho Namkoong, Quy Xiao Xuan Lin, Eliora Violain Buyamin, Le Min Tan, Radhika Sonthalia, Kyung Yeon Han, Hiromu Tanaka, Ho Lee, Tatsusada Okuno, Boxiang Liu, Koichi Matsuda, Koichi Fukunaga, Hideki Mochizuki, Woong-Yang Park, Kazuhiko Yamamoto, Chung-Chau Hon, Jay W. Shin, Shyam Prabhakar, Atsushi Kumanogoh, Yukinori Okada

Cell Genomics　p. 100625-100625　2024年7月　研究論文（学術雑誌）

Semaphorin 6D tunes amygdalar circuits for emotional, metabolic, and inflammatory outputs

Yoshimitsu Nakanishi, Mayuko Izumi, Hiroaki Matsushita, Yoshihisa Koyama, Diego Diez, Hyota Takamatsu, Shohei Koyama, Masayuki Nishide, Maiko Naito, Yumiko Mizuno, Yuta Yamaguchi, Tomoki Mae, Yu Noda, Kamon Nakaya, Satoshi Nojima, Fuminori Sugihara, Daisuke Okuzaki, Masahito Ikawa, Shoichi Shimada, Sujin Kang, Atsushi Kumanogoh

Neuron　2024年7月　研究論文（学術雑誌）

PlexinB1 inactivation reprograms immune cells in the tumor microenvironment, inhibiting breast cancer growth and metastatic dissemination.

Giulia Franzolin, Serena Brundu, Carina Florina Cojocaru, Aurora Curatolo, Matteo Ponzo, Roberta Mastrantonio, Emiko Mihara, Atsushi Kumanogoh, Hiroaki Suga, Junichi Takagi, Luca Tamagnone, Enrico Giraudo

Cancer immunology research　2024年6月14日　研究論文（学術雑誌）

SFTPB in serum extracellular vesicles as a biomarker of progressive pulmonary fibrosis.

Takatoshi Enomoto, Yuya Shirai, Yoshito Takeda, Ryuya Edahiro, Shigeyuki Shichino, Mana Nakayama, Miho Takahashi-Itoh, Yoshimi Noda, Yuichi Adachi, Takahiro Kawasaki, Taro Koba, Yu Futami, Moto Yaga, Yuki Hosono, Hanako Yoshimura, Saori Amiya, Reina Hara, Makoto Yamamoto, Daisuke Nakatsubo, Yasuhiko Suga, Maiko Naito, Kentaro Masuhiro, Haruhiko Hirata, Kota Iwahori, Izumi Nagatomo, Kotaro Miyake, Shohei Koyama, Kiyoharu Fukushima, Takayuki Shiroyama, Yujiro Naito, Shinji Futami, Yayoi Natsume-Kitatani, Satoshi Nojima, Masahiro Yanagawa, Yasushi Shintani, Mari Nogami-Itoh, Kenji Mizuguchi, Jun Adachi, Takeshi Tomonaga, Yoshikazu Inoue, Atsushi Kumanogoh

JCI insight　Vol. 9　No. 11　2024年6月10日　研究論文（学術雑誌）

ケラチノサイトにおけるセマフォリン4A発現低下は乾癬非病変部のモデルとなる

久米 美輝, 吉岡 華子, 金田 眞理, 渡辺 玲, 藤本 学, 熊ノ郷 淳

皮膚の科学　Vol. 23　No. 2　p. 151-151　2024年6月

Downregulation of Semaphorin 4A in keratinocytes reflects the features of non-lesional psoriasis

Miki Kume, Hanako Koguchi-Yoshioka, Shuichi Nakai, Yutaka Matsumura, Atsushi Tanemura, Kazunori Yokoi, Shoichi Matsuda, Yuumi Nakamura, Naoya Otani, Mifue Taminato, Koichi Tomita, Tateki Kubo, Mari Wataya-Kaneda, Atsushi Kumanogoh, Manabu Fujimoto, Rei Watanabe

2024年5月28日

Tetracyclines enhance antitumor T-cell immunity via the Zap70 signaling pathway

Mari Tone, Kota Iwahori, Michinari Hirata, Azumi Ueyama, Akiyoshi Tani, Jun-Ichi Haruta, Yoshito Takeda, Yasushi Shintani, Atsushi Kumanogoh, Hisashi Wada

Journal for ImmunoTherapy of Cancer　2024年4月　研究論文（学術雑誌）

Hypoglossal nerve palsy in IgG4-related disease

T Kaneko, Y Okita, Y Kato, M Narazaki, A Kumanogoh

QJM: An International Journal of Medicine　2024年3月27日　研究論文（学術雑誌）

Galectin-10 in serum extracellular vesicles reflects asthma pathophysiology.

Hanako Yoshimura, Yoshito Takeda, Yuya Shirai, Makoto Yamamoto, Daisuke Nakatsubo, Saori Amiya, Takatoshi Enomoto, Reina Hara, Yuichi Adachi, Ryuya Edahiro, Moto Yaga, Kentaro Masuhiro, Taro Koba, Miho Itoh-Takahashi, Mana Nakayama, So Takata, Yuki Hosono, Sho Obata, Masayuki Nishide, Akinori Hata, Masahiro Yanagawa, Satoko Namba, Michio Iwata, Momoko Hamano, Haruhiko Hirata, Shohei Koyama, Kota Iwahori, Izumi Nagatomo, Yasuhiko Suga, Kotaro Miyake, Takayuki Shiroyama, Kiyoharu Fukushima, Shinji Futami, Yujiro Naito, Takahiro Kawasaki, Kenji Mizuguchi, Yusuke Kawashima, Yoshihiro Yamanishi, Jun Adachi, Mari Nogami-Itoh, Shigeharu Ueki, Atsushi Kumanogoh

The Journal of allergy and clinical immunology　2024年3月14日　研究論文（学術雑誌）

免疫内科と整形外科によるRA患者のBio/JAK阻害剤治療の相違についての検討 関西多施設ANSWER cohortによる解析

惠谷 悠紀, 蛯名 耕介, 野口 貴明, 沖田 康孝, 辻本 考平, 白杉 郁, 山下 真依, 永井 孝治, 吉川 紋佳, 橋本 求, 岡野 匡志, 野崎 祐史, 伊丹 哲, 孫 瑛洙, 槇野 秀彦, 村田 浩一, 藤井 貴之, 山本 渉, 熊ノ郷 淳, 岡田 誠司

日本リウマチ学会総会・学術集会プログラム・抄録集　Vol. 68回　p. 859-859　2024年3月

肺非結核性抗酸菌症 肺Mycobacterium avium complex症におけるマクロライド耐性化の可塑性

安部 祐子, 福島 清春, 松本 悠希, 北田 清悟, 元岡 大祐, 新津 敬之, 新居 卓朗, 松本 隆典, 熊ノ郷 淳, 中村 昇太, 木田 博

日本呼吸器学会誌　Vol. 13　No. 増刊　p. 188-188　2024年3月

ゲノム解析が紐解くMycobacterium gordonae症の多様性

安部 祐子, 福島 清春, 松本 悠希, 松木 隆典, 元岡 大祐, 新津 敬之, 辻野 和之, 三木 啓資, 熊ノ郷 淳, 中村 昇太, 木田 博

日本呼吸器学会誌　Vol. 13　No. 増刊　p. 324-324　2024年3月

リアルタイムコアゲノム解析による非結核性抗酸菌症の迅速・高精度同定法の確立および臨床応用

新居 卓朗, 福島 清春, 松本 悠希, 松木 隆典, 元岡 大祐, 辻野 和之, 三木 啓資, 熊ノ郷 淳, 中村 昇太, 木田 博

日本呼吸器学会誌　Vol. 13　No. 増刊　p. 324-324　2024年3月

全身性強皮症におけるレイノー現象対策の薬剤費の調査結果

嶋 良仁, 渡邉 あかね, 水野 裕美子, 泉 真祐子, 辻本 考平, 糸田川 英里, 西出 真之, 加藤 保宏, 楢崎 雅司, 熊ノ郷 淳

日本リウマチ学会総会・学術集会プログラム・抄録集　Vol. 68回　p. 750-750　2024年3月

Progressive pulmonary fibrosisにおける抗線維化薬の効果の探索

新津 敬之, 福島 清春, 白山 敬之, 木田 博, 武田 吉人, 熊ノ郷 淳

日本呼吸器学会誌　Vol. 13　No. 増刊　p. 315-315　2024年3月

Pneumocephalus and Cerebral Abscess in Granulomatosis With Polyangiitis.

Yasutaka Okita, Masashi Okamoto, Jun Fujimoto, Atsushi Kumanogoh

The Journal of rheumatology　2024年3月1日　研究論文（学術雑誌）

Sema6D forward signaling impairs T cell activation and proliferation in head and neck cancer.

Takashi Hirai, Yujiro Naito, Shohei Koyama, Yoshimitsu Nakanishi, Kentaro Masuhiro, Mayuko Izumi, Tomoki Kuge, Maiko Naito, Yumiko Mizuno, Yuta Yamaguchi, Sujin Kang, Moto Yaga, Yu Futami, Satoshi Nojima, Masayuki Nishide, Takayoshi Morita, Yasuhiro Kato, Takeshi Tsuda, Norihiko Takemoto, Yumi Kinugasa-Katayama, Taiki Aoshi, Jordan Kelly Villa, Kazuo Yamashita, Tomohiro Enokida, Yuta Hoshi, Kazuto Matsuura, Makoto Tahara, Hyota Takamatsu, Yoshito Takeda, Hidenori Inohara, Atsushi Kumanogoh

JCI insight　Vol. 9　No. 3　2024年2月8日　研究論文（学術雑誌）

新技術が変える内科診療 患者検体シングルセル解析に基づいた膠原病疾患多様性の理解

西出 真之, 熊ノ郷 淳

日本内科学会雑誌　Vol. 113　No. 臨増　p. 102-102　2024年2月

Paradoxical improvement of dyspnoea in relapsing polychondritis by glucocorticoid tapering

Kenji Funakoshi, Yasuhiro Kato, Masashi Narazaki, Atsushi Kumanogoh

BMJ Case Reports　Vol. 17　No. 1　p. e257861-e257861　2024年1月24日　研究論文（学術雑誌）

Idiopathic pulmonary fibrosis-specific Bayesian network integrating extracellular vesicle proteome and clinical information

Mei Tomoto, Yohei Mineharu, Noriaki Sato, Yoshinori Tamada, Mari Nogami-Itoh, Masataka Kuroda, Jun Adachi, Yoshito Takeda, Kenji Mizuguchi, Atsushi Kumanogoh, Yayoi Natsume-Kitatani, Yasushi Okuno

Scientific Reports　Vol. 14　No. 1　2024年1月15日　研究論文（学術雑誌）

Cancer-associated SNRPD3 mutation confers resistance to hypoxia, which is attenuated by DRP1 inhibition.

Shingo Satoh, Kotaro Miyake, Yuichi Adachi, Kentaro Masuhiro, Shinji Futami, Yujiro Naito, Takayuki Shiroyama, Shohei Koyama, Yuta Yamaguchi, Hachiro Konaka, Hyota Takamatsu, Daisuke Okuzaki, Izumi Nagatomo, Yoshito Takeda, Atsushi Kumanogoh

Biochemical and biophysical research communications　Vol. 696　p. 149511-149511　2024年1月10日　研究論文（学術雑誌）

Real-world outcomes of nivolumab plus ipilimumab and pembrolizumab with platinum-based chemotherapy in advanced non-small cell lung cancer: a multicenter retrospective comparative study.

Kinnosuke Matsumoto, Takayuki Shiroyama, Motohiro Tamiya, Toshiyuki Minami, Yuhei Kinehara, Akihiro Tamiya, Yasuhiko Suga, Tomoki Kuge, Masahide Mori, Hidekazu Suzuki, Satoshi Tobita, Kiyonobu Ueno, Yoshinobu Namba, Satoshi Tetsumoto, Toshie Niki, Osamu Morimura, Akio Osa, Kazumi Nishino, Izumi Nagatomo, Yoshito Takeda, Takashi Kijima, Atsushi Kumanogoh

Cancer immunology, immunotherapy : CII　Vol. 73　No. 1　p. 4-4　2024年1月4日　研究論文（学術雑誌）

[LARGE-SCALE GENOME-WIDE ASSOCIATION STUDIES REVEAL THE GENETIC BACKGROUND OF AUTOIMMUNE AND ALLERGIC DISEASES].

Yuji Yamamoto, Yuya Shirai, Atsushi Kumanogoh, Yukinori Okada

Arerugi = [Allergy]　Vol. 73　No. 10　p. 1195-1199　2024年　研究論文（学術雑誌）

5,6-dimethylxanthenone-4-acetic acid (DMXAA), a partial STING agonist, competes for human STING activation.

Burcu Temizoz, Takayuki Shibahara, Kou Hioki, Tomoya Hayashi, Kouji Kobiyama, Michelle Sue Jann Lee, Naz Surucu, Erdal Sag, Atsushi Kumanogoh, Masahiro Yamamoto, Mayda Gursel, Seza Ozen, Etsushi Kuroda, Cevayir Coban, Ken J Ishii

Frontiers in immunology　Vol. 15　p. 1353336-1353336　2024年　研究論文（学術雑誌）

Single-cell transcriptome landscape of circulating CD4+ T cell populations in autoimmune diseases

Yoshiaki Yasumizu, Daiki Takeuchi, Reo Morimoto, Yusuke Takeshima, Tatsusada Okuno, Makoto Kinoshita, Takayoshi Morita, Yasuhiro Kato, Min Wang, Daisuke Motooka, Daisuke Okuzaki, Yamami Nakamura, Norihisa Mikami, Masaya Arai, Xuan Zhang, Atsushi Kumanogoh, Hideki Mochizuki, Naganari Ohkura, Shimon Sakaguchi

Cell Genomics　p. 100473-100473　2024年1月　研究論文（学術雑誌）

Estimating gene-level false discovery probability improves eQTL statistical fine-mapping precision.

Qingbo S Wang, Ryuya Edahiro, Ho Namkoong, Takanori Hasegawa, Yuya Shirai, Kyuto Sonehara, Atsushi Kumanogoh, Makoto Ishii, Ryuji Koike, Akinori Kimura, Seiya Imoto, Satoru Miyano, Seishi Ogawa, Takanori Kanai, Koichi Fukunaga, Yukinori Okada

NAR genomics and bioinformatics　Vol. 5　No. 4　2023年12月　研究論文（学術雑誌）

Analysis of gut microbiome, host genetics, and plasma metabolites reveals gut microbiome-host interactions in the Japanese population.

Yoshihiko Tomofuji, Toshihiro Kishikawa, Kyuto Sonehara, Yuichi Maeda, Kotaro Ogawa, Shuhei Kawabata, Eri Oguro-Igashira, Tatsusada Okuno, Takuro Nii, Makoto Kinoshita, Masatoshi Takagaki, Kenichi Yamamoto, Noriko Arase, Mayu Yagita-Sakamaki, Akiko Hosokawa, Daisuke Motooka, Yuki Matsumoto, Hidetoshi Matsuoka, Maiko Yoshimura, Shiro Ohshima, Shota Nakamura, Manabu Fujimoto, Hidenori Inohara, Haruhiko Kishima, Hideki Mochizuki, Kiyoshi Takeda, Atsushi Kumanogoh, Yukinori Okada

Cell reports　p. 113324-113324　2023年10月30日　研究論文（学術雑誌）

Single-cell multi-omics analysis identifies two distinct phenotypes of newly-onset microscopic polyangiitis.

Masayuki Nishide, Kei Nishimura, Hiroaki Matsushita, Ryuya Edahiro, Sachi Inukai, Hiroshi Shimagami, Shoji Kawada, Yasuhiro Kato, Takahiro Kawasaki, Kohei Tsujimoto, Hokuto Kamon, Ryusuke Omiya, Yukinori Okada, Kunihiro Hattori, Masashi Narazaki, Atsushi Kumanogoh

Nature communications　Vol. 14　No. 1　p. 5789-5789　2023年10月11日　研究論文（学術雑誌）

自己免疫性疾患患者におけるSARS-CoV-2 mRNAワクチン効果の持続性に関する検討

行木 紳一郎, 山口 勇太, 加藤 保宏, 村上 輝明, 吉峰 由子, 網屋 沙織, 森田 貴義, 沖田 康孝, 川崎 貴裕, 藤本 潤, 前田 悠一, 渡邊 あかね, 高松 漂太, 西田 純幸, 嶋 良仁, 楢崎 雅司, 熊ノ郷 淳

日本臨床免疫学会総会プログラム・抄録集　Vol. 51回　p. 121-121　2023年10月

疾患層別化、治療応用につながる免疫疾患の病態理解 患者検体シングルセル解析を基盤とした顕微鏡的多発血管炎に特徴的な細胞集団の同定

西出 真之, 熊ノ郷 淳

日本臨床免疫学会総会プログラム・抄録集　Vol. 51回　p. 52-52　2023年10月

Automatic evaluation of atlantoaxial subluxation in rheumatoid arthritis by a deep learning model

Yasutaka Okita, Toru Hirano, Bowen Wang, Yuta Nakashima, Saki Minoda, Hajime Nagahara, Atsushi Kumanogoh

Arthritis Research & Therapy　Vol. 25　No. 1　2023年9月25日　研究論文（学術雑誌）

Secretion of mitochondrial DNA via exosomes promotes inflammation in Behçet's syndrome.

Hachiro Konaka, Yasuhiro Kato, Toru Hirano, Kohei Tsujimoto, JeongHoon Park, Taro Koba, Wataru Aoki, Yusei Matsuzaki, Masayasu Taki, Shohei Koyama, Eri Itotagawa, Tatsunori Jo, Takehiro Hirayama, Taro Kawai, Ken J Ishii, Mitsuyoshi Ueda, Shigehiro Yamaguchi, Shizuo Akira, Takayoshi Morita, Yuichi Maeda, Masayuki Nishide, Sumiyuki Nishida, Yoshihito Shima, Masashi Narazaki, Hyota Takamatsu, Atsushi Kumanogoh

The EMBO journal　Vol. 42　No. 20　2023年9月4日　研究論文（学術雑誌）

The role of semaphorins in allergic diseases.

Maiko Naito, Atsushi Kumanogoh

Allergology international : official journal of the Japanese Society of Allergology　2023年8月25日　研究論文（学術雑誌）

A randomized phase 2 study on demeclocycline in patients with mild-to-moderate COVID-19.

Kota Iwahori, Takuro Nii, Norihiko Yamaguchi, Takahiro Kawasaki, Satomi Okamura, Kazuki Hashimoto, Takanori Matsuki, Kazuyuki Tsujino, Keisuke Miki, Akio Osa, Sho Goya, Kinya Abe, Masahide Mori, Yoshito Takeda, Tomomi Yamada, Hiroshi Kida, Atsushi Kumanogoh

Scientific reports　Vol. 13　No. 1　p. 13809-13809　2023年8月23日　研究論文（学術雑誌）

Disseminated non-tuberculous mycobacterial infection caused by Mycobacterium obuense in an immunocompromised patient: a case report.

Maiko Naito, Kentaro Fukushima, Shinsuke Kusakabe, Takaya Endo, Takayuki Shiroyama, Kika Ohira, Koji Azuma, Satoshi Tanizaki, Yumiko Yamamoto, Yuki Hosono, Yujiro Naito, Shinji Futami, Kotaro Miyake, Haruhiko Hirata, Yoshito Takeda, Atsushi Kumanogoh

BMC infectious diseases　Vol. 23　No. 1　p. 517-517　2023年8月8日　研究論文（学術雑誌）

Drug retention of biologics and Janus kinase inhibitors in patients with rheumatoid arthritis: the ANSWER cohort study.

Kosuke Ebina, Yuki Etani, Yuichi Maeda, Yasutaka Okita, Makoto Hirao, Wataru Yamamoto, Motomu Hashimoto, Koichi Murata, Ryota Hara, Koji Nagai, Yuri Hiramatsu, Yonsu Son, Hideki Amuro, Takayuki Fujii, Takaichi Okano, Yo Ueda, Masaki Katayama, Tadashi Okano, Shotaro Tachibana, Shinya Hayashi, Atsushi Kumanogoh, Seiji Okada, Ken Nakata

RMD open　Vol. 9　No. 3　2023年8月　研究論文（学術雑誌）

Expression of the readthrough transcript CiDRE in alveolar macrophages boosts SARS-CoV-2 susceptibility and promotes COVID-19 severity

Yuichi Mitsui, Tatsuya Suzuki, Kanako Kuniyoshi, Jun Inamo, Kensuke Yamaguchi, Mariko Komuro, Junya Watanabe, Mio Edamoto, Songling Li, Tsukasa Kouno, Seiya Oba, Tadashi Hosoya, Kentaro Masuhiro, Yujiro Naito, Shohei Koyama, Nobuo Sakaguchi, Daron M. Standley, Jay W. Shin, Shizuo Akira, Shinsuke Yasuda, Yasunari Miyazaki, Yuta Kochi, Atsushi Kumanogoh, Toru Okamoto, Takashi Satoh

Immunity　2023年7月　研究論文（学術雑誌）

A cancer-associated METTL14 mutation induces aberrant m6A modification, affecting tumor growth

Kotaro Miyake, Pedro Henrique Costa Cruz, Izumi Nagatomo, Yuki Kato, Daisuke Motooka, Shingo Satoh, Yuichi Adachi, Yoshito Takeda, Yukio Kawahara, Atsushi Kumanogoh

Cell Reports　Vol. 42　No. 7　p. 112688-112688　2023年7月　研究論文（学術雑誌）

Single-cell Raman microscopy with machine learning highlights distinct biochemical features of neutrophil extracellular traps and necrosis.

Patrick Michael Lelliott, Alison Jane Hobro, Nicolas Pavillon, Masayuki Nishide, Yasutaka Okita, Yumiko Mizuno, Sho Obata, Shinichiro Nameki, Hanako Yoshimura, Atsushi Kumanogoh, Nicholas Isaac Smith

Scientific reports　Vol. 13　No. 1　p. 10093-10093　2023年6月21日　研究論文（学術雑誌）

T cell immunity in interstitial lung disease with non-small cell lung cancer patients.

Tomomi Isono, Kota Iwahori, Masahiro Yanagawa, Yoko Yamamoto, Mari Tone, Miya Haruna, Michinari Hirata, Eriko Fukui, Toru Kimura, Takashi Kanou, Naoko Ose, Soichiro Funaki, Yoshito Takeda, Eiichi Morii, Atsushi Kumanogoh, Yasushi Shintani, Hisashi Wada

Lung cancer (Amsterdam, Netherlands)　Vol. 182　p. 107278-107278　2023年6月9日　研究論文（学術雑誌）

Pathophysiological functions of semaphorins in the sympathetic nervous system.

Yumiko Mizuno, Yoshimitsu Nakanishi, Atsushi Kumanogoh

Inflammation and regeneration　Vol. 43　No. 1　p. 30-30　2023年6月8日　研究論文（学術雑誌）

Corrigendum to Semaphorin 4C and 4G are ligands of Plexin-B2 required in cerebellar development [Mol. Cell. Neurosci., 2011 Feb;46(2):419-31].

Viola Maier, Christine Jolicoeur, Helen Rayburn, Noriko Takegahara, Atsushi Kumanogoh, Hitoshi Kikutani, Marc Tessier-Lavigne, Wolfgang Wurst, Roland H Friedel

Molecular and cellular neurosciences　Vol. 125　p. 103837-103837　2023年6月

Impact of minocycline on outcomes of EGFR-mutant non-small cell lung cancer patients treated with EGFR-TKIs.

Mari Tone, Kota Iwahori, Takayuki Shiroyama, Shinji Futami, Yujiro Naito, Kiyoharu Fukushima, Kotaro Miyake, Shohei Koyama, Haruhiko Hirata, Izumi Nagatomo, Hisashi Wada, Yoshito Takeda, Atsushi Kumanogoh

Scientific reports　Vol. 13　No. 1　p. 8313-8313　2023年5月23日　研究論文（学術雑誌）

Tumor-derived semaphorin 4A improves PD-1-blocking antibody efficacy by enhancing CD8+ T cell cytotoxicity and proliferation.

Yujiro Naito, Shohei Koyama, Kentaro Masuhiro, Takashi Hirai, Takeshi Uenami, Takako Inoue, Akio Osa, Hirotomo Machiyama, Go Watanabe, Nicolas Sax, Jordan Villa, Yumi Kinugasa-Katayama, Satoshi Nojima, Moto Yaga, Yuki Hosono, Daisuke Okuzaki, Shingo Satoh, Takeshi Tsuda, Yoshimitsu Nakanishi, Yasuhiko Suga, Takayoshi Morita, Kiyoharu Fukushima, Masayuki Nishide, Takayuki Shiroyama, Kotaro Miyake, Kota Iwahori, Haruhiko Hirata, Izumi Nagatomo, Yukihiro Yano, Motohiro Tamiya, Toru Kumagai, Norihiko Takemoto, Hidenori Inohara, Sho Yamasaki, Kazuo Yamashita, Taiki Aoshi, Esra A Akbay, Naoki Hosen, Yasushi Shintani, Hyota Takamatsu, Masahide Mori, Yoshito Takeda, Atsushi Kumanogoh

Science advances　Vol. 9　No. 20　2023年5月19日　研究論文（学術雑誌）

Reconstruction of the personal information from human genome reads in gut metagenome sequencing data.

Yoshihiko Tomofuji, Kyuto Sonehara, Toshihiro Kishikawa, Yuichi Maeda, Kotaro Ogawa, Shuhei Kawabata, Takuro Nii, Tatsusada Okuno, Eri Oguro-Igashira, Makoto Kinoshita, Masatoshi Takagaki, Kenichi Yamamoto, Takashi Kurakawa, Mayu Yagita-Sakamaki, Akiko Hosokawa, Daisuke Motooka, Yuki Matsumoto, Hidetoshi Matsuoka, Maiko Yoshimura, Shiro Ohshima, Shota Nakamura, Hidenori Inohara, Haruhiko Kishima, Hideki Mochizuki, Kiyoshi Takeda, Atsushi Kumanogoh, Yukinori Okada

Nature microbiology　Vol. 8　No. 6　p. 1079-1094　2023年5月15日　研究論文（学術雑誌）

Food additive succinate exacerbates experimental autoimmune encephalomyelitis accompanied by increased IL-1β production.

Yasuko Sugiyama, Kazushiro Takata, Makoto Kinoshita, Daisuke Motooka, Naoyuki Shiraishi, Keigo Kihara, Hisashi Murata, Shohei Beppu, Toru Koda, Kazuya Yamashita, Akiko Namba, Kosuke Fujimoto, Atsushi Kumanogoh, Tatsusada Okuno, Hideki Mochizuki

Biochemical and biophysical research communications　Vol. 656　p. 97-103　2023年5月14日　研究論文（学術雑誌）

The Ragulator complex: delving its multifunctional impact on metabolism and beyond.

Kohei Tsujimoto, Hyota Takamatsu, Atsushi Kumanogoh

Inflammation and regeneration　Vol. 43　No. 1　p. 28-28　2023年5月12日　研究論文（学術雑誌）

Impact of Lymphopenia Recovery After Chemoradiotherapy on Durvalumab Consolidation Therapy in Stage III NSCLC.

Tomoki Kuge, Takayuki Shiroyama, Akihiro Tamiya, Motohiro Tamiya, Masaki Kanazu, Yuhei Kinehara, Tsunehiro Tanaka, Osamu Morimura, Yoshihiko Taniguchi, Toshie Niki, Satoshi Tetsumoto, Kazuhiko Hayashi, Kazumi Nishino, Izumi Nagatomo, Atsushi Kumanogoh

JTO clinical and research reports　Vol. 4　No. 5　p. 100505-100505　2023年5月　研究論文（学術雑誌）

Impact of respiratory bacterial infections on mortality in Japanese patients with COVID-19: a retrospective cohort study.

Kensuke Nakagawara, Hirofumi Kamata, Shotaro Chubachi, Ho Namkoong, Hiromu Tanaka, Ho Lee, Shiro Otake, Takahiro Fukushima, Tatsuya Kusumoto, Atsuho Morita, Shuhei Azekawa, Mayuko Watase, Takanori Asakura, Katsunori Masaki, Makoto Ishii, Akifumi Endo, Ryuji Koike, Hiroyasu Ishikura, Tohru Takata, Yasushi Matsushita, Norihiro Harada, Hiroyuki Kokutou, Takashi Yoshiyama, Kensuke Kataoka, Yoshikazu Mutoh, Masayoshi Miyawaki, Soichiro Ueda, Hiroshi Ono, Takuya Ono, Tomohisa Shoko, Hiroyuki Muranaka, Kodai Kawamura, Nobuaki Mori, Takao Mochimaru, Mototaka Fukui, Yusuke Chihara, Yoji Nagasaki, Masaki Okamoto, Masaru Amishima, Toshio Odani, Mayuko Tani, Koichi Nishi, Yuya Shirai, Ryuya Edahiro, Akira Ando, Naozumi Hashimoto, Shinji Ogura, Yuichiro Kitagawa, Toshiyuki Kita, Takashi Kagaya, Yasuhiro Kimura, Naoki Miyazawa, Tomoya Tsuchida, Shigeki Fujitani, Koji Murakami, Hirohito Sano, Yuki Sato, Yoshinori Tanino, Ryo Otsuki, Shuko Mashimo, Mizuki Kuramochi, Yasuo Hosoda, Yoshinori Hasegawa, Tetsuya Ueda, Yotaro Takaku, Takashi Ishiguro, Akiko Fujiwara, Naota Kuwahara, Hideya Kitamura, Eri Hagiwara, Yasushi Nakamori, Fukuki Saito, Yuta Kono, Shinji Abe, Tomoo Ishii, Takehiko Ohba, Yu Kusaka, Hiroko Watanabe, Makoto Masuda, Hiroki Watanabe, Yoshifumi Kimizuka, Akihiko Kawana, Yu Kasamatsu, Satoru Hashimoto, Yukinori Okada, Tomomi Takano, Kazuhiko Katayama, Masumi Ai, Atsushi Kumanogoh, Toshiro Sato, Katsushi Tokunaga, Seiya Imoto, Yuko Kitagawa, Akinori Kimura, Satoru Miyano, Naoki Hasegawa, Seishi Ogawa, Takanori Kanai, Koichi Fukunaga

BMC pulmonary medicine　Vol. 23　No. 1　p. 146-146　2023年4月26日　研究論文（学術雑誌）

Single-cell analyses and host genetics highlight the role of innate immune cells in COVID-19 severity.

Ryuya Edahiro, Yuya Shirai, Yusuke Takeshima, Shuhei Sakakibara, Yuta Yamaguchi, Teruaki Murakami, Takayoshi Morita, Yasuhiro Kato, Yu-Chen Liu, Daisuke Motooka, Yoko Naito, Ayako Takuwa, Fuminori Sugihara, Kentaro Tanaka, James B Wing, Kyuto Sonehara, Yoshihiko Tomofuji, Ho Namkoong, Hiromu Tanaka, Ho Lee, Koichi Fukunaga, Haruhiko Hirata, Yoshito Takeda, Daisuke Okuzaki, Atsushi Kumanogoh, Yukinori Okada

Nature genetics　Vol. 55　No. 5　p. 753-767　2023年4月24日　研究論文（学術雑誌）

Identifying phenotypes in interstitial lung disease using group-based trajectory modelling.

S Takata, S Komukai, T Hoshino, H Tabuchi, K Masuhiro, M Yaga, Y Shirai, Y Mitsui, Y Abe, T Kuge, K Fukushima, H Kida, A Kumanogoh

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease　Vol. 27　No. 4　p. 332-334　2023年4月1日　研究論文（学術雑誌）

Celastrol suppresses humoral immune responses and autoimmunity by targeting the COMMD3/8 complex

Taiichiro Shirai, Akiko Nakai, Emiko Ando, Jun Fujimoto, Sarah Leach, Takao Arimori, Daisuke Higo, Floris J. van Eerden, Janyerkye Tulyeu, Yu-Chen Liu, Daisuke Okuzaki, Masanori A. Murayama, Haruhiko Miyata, Kazuto Nunomura, Bangzhong Lin, Akiyoshi Tani, Atsushi Kumanogoh, Masahito Ikawa, James B. Wing, Daron M. Standley, Junichi Takagi, Kazuhiro Suzuki

Science Immunology　Vol. 8　No. 81　2023年3月31日　研究論文（学術雑誌）

Gut dysbiosis is associated with aortic aneurysm formation and progression in Takayasu arteritis.

Yusuke Manabe, Tomohiko Ishibashi, Ryotaro Asano, Shuichi Tonomura, Yuichi Maeda, Daisuke Motooka, Jin Ueda, Masahiro Yanagawa, Yuko Edamoto-Taira, Tomomi Chikaishi-Kirino, Takeshi Masaki, Tadakatsu Inagaki, Shota Nakamura, Yoshinori Katada, Makoto Okazawa, Masashi Narazaki, Takeshi Ogo, Atsushi Kumanogoh, Yoshikazu Nakaoka

Arthritis research & therapy　Vol. 25　No. 1　p. 46-46　2023年3月24日　研究論文（学術雑誌）

MGIT-seq for the Identification of Nontuberculous Mycobacteria and Drug Resistance: a Prospective Study.

Kiyoharu Fukushima, Yuki Matsumoto, Takanori Matsuki, Haruko Saito, Daisuke Motooka, Sho Komukai, Eriko Fukui, June Yamuchi, Tadayoshi Nitta, Takayuki Niitsu, Yuko Abe, Hiroshi Nabeshima, Yasuharu Nagahama, Takuro Nii, Kazuyuki Tsujino, Keisuke Miki, Seigo Kitada, Atsushi Kumanogoh, Shizuo Akira, Shota Nakamura, Hiroshi Kida

Journal of clinical microbiology　Vol. 61　No. 4　2023年3月22日　研究論文（学術雑誌）

Group 2 innate lymphoid cells and their surrounding environment.

Maiko Naito, Atsushi Kumanogoh

Inflammation and regeneration　Vol. 43　No. 1　p. 21-21　2023年3月20日　研究論文（学術雑誌）

リアルワールドにおけるPF-ILDに対する抗線維化薬の長期的効果の検証及び,慢性間質性肺炎の多様なフェノタイプの同定

新津 敬之, 福島 清春, 高田 壮, 小向 翔, 武田 吉人, 木田 博, 熊ノ郷 淳

日本呼吸器学会誌　Vol. 12　No. 増刊　p. 218-218　2023年3月

Virtual fluoroscopic preprocedural planning using Ziostation2 for transbronchial biopsy: A prospective self-controlled study.

Yuko Abe, Kotaro Miyake, Takayuki Shiroyama, Haruhiko Hirata, Izumi Nagatomo, Yoshito Takeda, Atsushi Kumanogoh

Respiratory investigation　Vol. 61　No. 2　p. 157-163　2023年3月　研究論文（学術雑誌）

DOCK2は日本人集団におけるCOVID-19の重症化遺伝子で,宿主免疫応答に重要な役割を担う

南宮 湖, 枝廣 龍哉, 高野 友美, 西原 広史, 熊ノ郷 淳, 小池 竜司, 木村 彰方, 井元 清哉, 宮野 悟, 小川 誠司, 金井 隆典, 岡田 随象, 福永 興壱

日本呼吸器学会誌　Vol. 12　No. 増刊　p. 271-271　2023年3月　研究論文（学術雑誌）

COVID-19 トランスレーショナルリサーチ 日本人での大規模シングルセルRNA-seqにより明らかになったCOVID-19重症化における自然免疫細胞の生物学的・宿主遺伝学的な関与

枝廣 龍哉, 白井 雄也, 奥崎 大介, 平田 陽彦, 武田 吉人, 熊ノ郷 淳, 岡田 随象

日本呼吸器学会誌　Vol. 12　No. 増刊　p. 176-176　2023年3月

Direct activation of microglia by β-glucosylceramide causes phagocytosis of neurons that exacerbates Gaucher disease.

Takashi Shimizu, Charles R Schutt, Yoshihiro Izumi, Noriyuki Tomiyasu, Zakaria Omahdi, Kuniyuki Kano, Hyota Takamatsu, Junken Aoki, Takeshi Bamba, Atsushi Kumanogoh, Masaki Takao, Sho Yamasaki

Immunity　Vol. 56　No. 2　p. 307-319　2023年2月14日　研究論文（学術雑誌）

A sex-biased imbalance between Tfr, Tph, and atypical B cells determines antibody responses in COVID-19 patients.

Jonas Nørskov Søndergaard, Janyerkye Tulyeu, Ryuya Edahiro, Yuya Shirai, Yuta Yamaguchi, Teruaki Murakami, Takayoshi Morita, Yasuhiro Kato, Haruhiko Hirata, Yoshito Takeda, Daisuke Okuzaki, Shimon Sakaguchi, Atsushi Kumanogoh, Yukinori Okada, James Badger Wing

Proceedings of the National Academy of Sciences of the United States of America　Vol. 120　No. 4　2023年1月24日　研究論文（学術雑誌）

Genomic repertoires linked with pathogenic potency of arthritogenic Prevotella copri isolated from the gut of patients with rheumatoid arthritis.

Takuro Nii, Yuichi Maeda, Daisuke Motooka, Mariko Naito, Yuki Matsumoto, Takao Ogawa, Eri Oguro-Igashira, Toshihiro Kishikawa, Makoto Yamashita, Satoshi Koizumi, Takashi Kurakawa, Ryu Okumura, Hisako Kayama, Mari Murakami, Taiki Sakaguchi, Bhabatosh Das, Shota Nakamura, Yukinori Okada, Atsushi Kumanogoh, Kiyoshi Takeda

Annals of the rheumatic diseases　Vol. 82　No. 5　p. 621-629　2023年1月10日　研究論文（学術雑誌）

Efficacy and risk of mRNA vaccination in patients with autoimmune inflammatory rheumatic diseases

Yasuhiro Kato, Takayoshi Morita, Atsushi Kumanogoh

Inflammation and Regeneration　Vol. 43　No. 1　2023年1月6日　研究論文（学術雑誌）

WT1 Trio Peptide-Based Cancer Vaccine for Rare Cancers Expressing Shared Target WT1

Yusuke Oji, Naoki Kagawa, Hideyuki Arita, Norifumi Naka, Ken-ichiro Hamada, Hidetatsu Outani, Yasushi Shintani, Yoshito Takeda, Eiichi Morii, Kenzo Shimazu, Motoyuki Suzuki, Sumiyuki Nishida, Jun Nakata, Akihiro Tsuboi, Miki Iwai, Sae Hayashi, Rin Imanishi, Sayaka Ikejima, Mizuki Kanegae, Masahiro Iwamoto, Mayu Ikeda, Kento Yagi, Haruka Shimokado, Hiroko Nakajima, Kana Hasegawa, Soyoko Morimoto, Fumihiro Fujiki, Akira Nagahara, Atsushi Tanemura, Yutaka Ueda, Tsunekazu Mizushima, Masato Ohmi, Takayuki Ishida, Manabu Fujimoto, Norio Nonomura, Tadashi Kimura, Hidenori Inohara, Seiji Okada, Haruhiko Kishima, Naoki Hosen, Atsushi Kumanogoh, Yoshihiro Oka, Haruo Sugiyama

Cancers　Vol. 15　No. 2　p. 393-393　2023年1月6日　研究論文（学術雑誌）

Secondary subcutaneous abscess due to mixed infections by Peptoniphilus olsenii and Gleimia europaea after COVID-19.

Yuji Yamamoto, Takayuki Shiroyama, Haruhiko Hirata, Kinnosuke Matsumoto, Tomoki Kuge, Midori Yoneda, Makoto Yamamoto, Akinori Uchiyama, Yoshito Takeda, Atsushi Kumanogoh

Clinical case reports　Vol. 11　No. 1　2023年1月

Real-world impact of antifibrotics on prognosis in patients with progressive fibrosing interstitial lung disease.

Takayuki Niitsu, Kiyoharu Fukushima, Sho Komukai, So Takata, Yuko Abe, Takuro Nii, Tomoki Kuge, Shinichi Iwakoshi, Takayuki Shiroyama, Kotaro Miyake, Kazuyuki Tujino, Satoshi Tanizaki, Kota Iwahori, Haruhiko Hirata, Keisuke Miki, Masahiro Yanagawa, Noriyuki Takeuchi, Yoshito Takeda, Hiroshi Kida, Atsushi Kumanogoh

RMD open　Vol. 9　No. 1　2023年1月　研究論文（学術雑誌）

A case of Takayasu arteritis complicated with pulmonary infarction

Takehiro Hirayama, Takayoshi Morita, Kenji Funakoshi, Yuko Yoshimine, Saki Minoda, Teruaki Murakami, Yasutaka Okita, Masashi Narazaki, Atsushi Kumanogoh

Oxford Medical Case Reports　Vol. 2022　No. 12　2022年12月1日　研究論文（学術雑誌）

Persistence of SARS-CoV-2 neutralizing antibodies and anti-Omicron IgG induced by BNT162b2 mRNA vaccine in patients with autoimmune inflammatory rheumatic disease: An explanatory study in Japan

Yuta Yamaguchi, Shinichiro Nameki, Yasuhiro Kato, Ryotaro Saita, Tomoharu Sato, Sayaka Nagao, Teruaki Murakami, Yuko Yoshimine, Saori Amiya, Takayoshi Morita, Yasutaka Okita, Takahiro Kawasaki, Jun Fujimoto, Yasutaka Ueda, Yuichi Maeda, Akane Watanabe, Hyota Takamatsu, Sumiyuki Nishida, Yoshihito Shima, Masashi Narazaki, Atsushi Kumanogoh

The Lancet Regional Health - Western Pacific　p. 100661-100661　2022年12月　研究論文（学術雑誌）

Prokaryotic and viral genomes recovered from 787 Japanese gut metagenomes revealed microbial features linked to diets, populations, and diseases

Yoshihiko Tomofuji, Toshihiro Kishikawa, Yuichi Maeda, Kotaro Ogawa, Yuriko Otake-Kasamoto, Shuhei Kawabata, Takuro Nii, Tatsusada Okuno, Eri Oguro-Igashira, Makoto Kinoshita, Masatoshi Takagaki, Naoki Oyama, Kenichi Todo, Kenichi Yamamoto, Kyuto Sonehara, Mayu Yagita, Akiko Hosokawa, Daisuke Motooka, Yuki Matsumoto, Hidetoshi Matsuoka, Maiko Yoshimura, Shiro Ohshima, Shinichiro Shinzaki, Shota Nakamura, Hideki Iijima, Hidenori Inohara, Haruhiko Kishima, Tetsuo Takehara, Hideki Mochizuki, Kiyoshi Takeda, Atsushi Kumanogoh, Yukinori Okada

Cell Genomics　Vol. 2　No. 12　p. 100219-100219　2022年12月　研究論文（学術雑誌）

PlexinA1-deficient mice exhibit decreased cell density and augmented oxidative stress in parvalbumin-expressing interneurons in the medial prefrontal cortex

Mst Sharifa Jahan, Takamasa Tsuzuki, Takuji Ito, Md. Eliusur Rahman Bhuiyan, Ikuko Takahashi, Hyota Takamatsu, Atsushi Kumanogoh, Takayuki Negishi, Kazunori Yukawa

IBRO Neuroscience Reports　Vol. 13　p. 500-512　2022年12月　研究論文（学術雑誌）

Next-generation proteomics of serum extracellular vesicles combined with single-cell RNA sequencing identifies MACROH2A1 associated with refractory COVID-19.

Takahiro Kawasaki, Yoshito Takeda, Ryuya Edahiro, Yuya Shirai, Mari Nogami-Itoh, Takanori Matsuki, Hiroshi Kida, Takatoshi Enomoto, Reina Hara, Yoshimi Noda, Yuichi Adachi, Takayuki Niitsu, Saori Amiya, Yuta Yamaguchi, Teruaki Murakami, Yasuhiro Kato, Takayoshi Morita, Hanako Yoshimura, Makoto Yamamoto, Daisuke Nakatsubo, Kotaro Miyake, Takayuki Shiroyama, Haruhiko Hirata, Jun Adachi, Yukinori Okada, Atsushi Kumanogoh

Inflammation and regeneration　Vol. 42　No. 1　p. 53-53　2022年11月30日　研究論文（学術雑誌）

The lysosomal Ragulator complex activates NLRP3 inflammasome in vivo via HDAC6.

Kohei Tsujimoto, Tatsunori Jo, Daiki Nagira, Hachiro Konaka, Jeong Hoon Park, Shin-Ichiro Yoshimura, Akinori Ninomiya, Fuminori Sugihara, Takehiro Hirayama, Eri Itotagawa, Yusei Matsuzaki, Yuki Takaichi, Wataru Aoki, Shotaro Saita, Shuhei Nakamura, Andrea Ballabio, Shigeyuki Nada, Masato Okada, Hyota Takamatsu, Atsushi Kumanogoh

The EMBO journal　Vol. 42　No. 1　2022年11月29日　研究論文（学術雑誌）

Proposal of a novel pipeline involving precise bronchoscopy of distal peripheral pulmonary lesions for genetic testing.

So Takata, Kotaro Miyake, Daichi Maeda, Kazue Hatake, Izumi Nagatomo, Takayuki Shiroyama, Kentaro Masuhiro, Moto Yaga, Yuya Shirai, Yuichi Mitsui, Shinichi Yachida, Atsushi Kumanogoh

Scientific reports　Vol. 12　No. 1　p. 19774-19774　2022年11月17日　研究論文（学術雑誌）

Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis.

Kazuyoshi Ishigaki, Saori Sakaue, Chikashi Terao, Yang Luo, Kyuto Sonehara, Kensuke Yamaguchi, Tiffany Amariuta, Chun Lai Too, Vincent A Laufer, Ian C Scott, Sebastien Viatte, Meiko Takahashi, Koichiro Ohmura, Akira Murasawa, Motomu Hashimoto, Hiromu Ito, Mohammed Hammoudeh, Samar Al Emadi, Basel K Masri, Hussein Halabi, Humeira Badsha, Imad W Uthman, Xin Wu, Li Lin, Ting Li, Darren Plant, Anne Barton, Gisela Orozco, Suzanne M M Verstappen, John Bowes, Alexander J MacGregor, Suguru Honda, Masaru Koido, Kohei Tomizuka, Yoichiro Kamatani, Hiroaki Tanaka, Eiichi Tanaka, Akari Suzuki, Yuichi Maeda, Kenichi Yamamoto, Satoru Miyawaki, Gang Xie, Jinyi Zhang, Christopher I Amos, Edward Keystone, Gertjan Wolbink, Irene van der Horst-Bruinsma, Jing Cui, Katherine P Liao, Robert J Carroll, Hye-Soon Lee, So-Young Bang, Katherine A Siminovitch, Niek de Vries, Lars Alfredsson, Solbritt Rantapää-Dahlqvist, Elizabeth W Karlson, Sang-Cheol Bae, Robert P Kimberly, Jeffrey C Edberg, Xavier Mariette, Tom Huizinga, Philippe Dieudé, Matthias Schneider, Martin Kerick, Joshua C Denny, Koichi Matsuda, Keitaro Matsuo, Tsuneyo Mimori, Fumihiko Matsuda, Keishi Fujio, Yoshiya Tanaka, Atsushi Kumanogoh, Matthew Traylor, Cathryn M Lewis, Stephen Eyre, Huji Xu, Richa Saxena, Thurayya Arayssi, Yuta Kochi, Katsunori Ikari, Masayoshi Harigai, Peter K Gregersen, Kazuhiko Yamamoto, S Louis Bridges Jr, Leonid Padyukov, Javier Martin, Lars Klareskog, Yukinori Okada, Soumya Raychaudhuri

Nature genetics　Vol. 54　No. 11　p. 1640-1651　2022年11月　研究論文（学術雑誌）

Semaphorin 6D-expressing mesenchymal cells regulate IL-10 production by ILC2s in the lung.

Maiko Naito, Yoshimitsu Nakanishi, Yasutaka Motomura, Hyota Takamatsu, Shohei Koyama, Masayuki Nishide, Yujiro Naito, Mayuko Izumi, Yumiko Mizuno, Yuta Yamaguchi, Satoshi Nojima, Daisuke Okuzaki, Atsushi Kumanogoh

Life science alliance　Vol. 5　No. 11　2022年11月　研究論文（学術雑誌）

Consecutive BNT162b2 mRNA vaccination induces short-term epigenetic memory in innate immune cells.

Yuta Yamaguchi, Yasuhiro Kato, Ryuya Edahiro, Jonas N Søndergaard, Teruaki Murakami, Saori Amiya, Shinichiro Nameki, Yuko Yoshimine, Takayoshi Morita, Yusuke Takeshima, Shuhei Sakakibara, Yoko Naito, Daisuke Motooka, Yu-Chen Liu, Yuya Shirai, Yasutaka Okita, Jun Fujimoto, Haruhiko Hirata, Yoshito Takeda, James B Wing, Daisuke Okuzaki, Yukinori Okada, Atsushi Kumanogoh

JCI insight　Vol. 7　No. 22　2022年10月25日　研究論文（学術雑誌）

Peripheral T cell cytotoxicity predicts the efficacy of anti-PD-1 therapy for advanced non-small cell lung cancer patients.

Kota Iwahori, Takeshi Uenami, Yukihiro Yano, Toshihiko Ueda, Mari Tone, Yujiro Naito, Yasuhiko Suga, Kiyoharu Fukushima, Takayuki Shiroyama, Kotaro Miyake, Shohei Koyama, Haruhiko Hirata, Izumi Nagatomo, Hiroshi Kida, Masahide Mori, Yoshito Takeda, Atsushi Kumanogoh, Hisashi Wada

Scientific reports　Vol. 12　No. 1　p. 17461-17461　2022年10月19日　研究論文（学術雑誌）

CiDRE⁺ M2c macrophages hijacked by SARS-CoV-2 cause COVID-19 severity

Yuichi Mitsui, Tatsuya Suzuki, Kanako Kuniyoshi, Jun Inamo, Kensuke Yamaguchi, Mariko Komuro, Junya Watanabe, Mio Edamoto, Songling Li, Tsukasa Kouno, Seiya Oba, Tadashi Hosoya, Shohei Koyama, Nobuo Sakaguchi, Daron M. Standley, Jay W. Shin, Shizuo Akira, Shinsuke Yasuda, Yasunari Miyazaki, Yuta Kochi, Atsushi Kumanogoh, Toru Okamoto, Takashi Satoh

2022年10月3日

多発性硬化症治療におけるDMD反応性と免疫セマホリンSema4Aの関連の検討

甲田 亨, 奥野 龍禎, 木下 允, 望月 秀樹, 宮本 勝一, 新野 正明, 清水 優子, 山本 真守, 熊ノ郷 淳, 中辻 裕司

臨床神経学　Vol. 62　No. Suppl.　p. S331-S331　2022年10月　研究論文（学術雑誌）

DOCK2 is involved in the host genetics and biology of severe COVID-19

Ho Namkoong, Ryuya Edahiro, Tomomi Takano, Hiroshi Nishihara, Yuya Shirai, Kyuto Sonehara, Hiromu Tanaka, Shuhei Azekawa, Yohei Mikami, Ho Lee, Takanori Hasegawa, Atsushi Kumanogoh, Toshiro Sato, Naoki Hasegawa, Katsushi Tokunaga, Makoto Ishii, Ryuji Koike, Yuko Kitagawa, Akinori Kimura, Seiya Imoto, Satoru Miyano, Seishi Ogawa, Takanori Kanai, Koichi Fukunaga, Yukinori Okada et al.

Nature　Vol. 609　No. 7928　p. 754-760　2022年9月22日　研究論文（学術雑誌）

Arm heating to relieve Raynaud's phenomenon in systemic sclerosis: A single-arm multicentre prospective clinical trial.

Akane Watanabe, Yoshihito Shima, Hiroki Takahashi, Yuji Akiyama, Masanari Kodera, Masatoshi Jinnin, Naoto Azuma, Koji Ishii, Atsushi Kumanogoh

Modern rheumatology　2022年9月19日　研究論文（学術雑誌）

SLE stratification based on BAFF and IFN-I bioactivity for biologics and implications of BAFF produced by glomeruli in lupus nephritis.

Eri Itotagawa, Yoshihiko Tomofuji, Yasuhiro Kato, Hachiro Konaka, Kohei Tsujimoto, JeongHoon Park, Daiki Nagira, Takehiro Hirayama, Tatsunori Jo, Toru Hirano, Takayoshi Morita, Masayuki Nishide, Sumiyuki Nishida, Yoshihito Shima, Masashi Narazaki, Yukinori Okada, Hyota Takamatsu, Atsushi Kumanogoh

Rheumatology (Oxford, England)　Vol. 62　No. 5　p. 1988-1997　2022年9月12日　研究論文（学術雑誌）

Impact of treatment line on risks and benefits of immune checkpoint inhibitor in patients with advanced non-small cell lung cancer and interstitial lung disease: a systematic review and meta-analysis of cohort studies.

Kinnosuke Matsumoto, Takayuki Shiroyama, Tomoki Kuge, Kotaro Miyake, Yuji Yamamoto, Midori Yoneda, Makoto Yamamoto, Yujiro Naito, Yasuhiko Suga, Kiyoharu Fukushima, Shohei Koyama, Kota Iwahori, Haruhiko Hirata, Izumi Nagatomo, Yoshito Takeda, Atsushi Kumanogoh

Translational lung cancer research　Vol. 11　No. 9　p. 1835-1846　2022年9月　研究論文（学術雑誌）

The proliferative activity levels of each immune cell population evaluated by mass cytometry are linked to the clinical phenotypes of systemic lupus erythematosus.

Kajihara Akiko, Takayoshi Morita, Yasuhiro Kato, Hachiro Konaka, Teruaki Murakami, Yuta Yamaguchi, Shohei Koyama, Hyota Takamatsu, Masayuki Nishide, Yuichi Maeda, Akane Watanabe, Sumiyuki Nishida, Toru Hirano, Yoshihito Shima, Masashi Narazaki, Atsushi Kumanogoh

International immunology　Vol. 35　No. 1　p. 27-41　2022年8月23日　研究論文（学術雑誌）

Add-on Effectiveness of Methotrexate or Iguratimod in Patients with Rheumatoid Arthritis Exhibiting an Inadequate Response to Janus Kinase Inhibitors: The ANSWER Cohort Study.

Kosuke Ebina, Toru Hirano, Yuichi Maeda, Yasutaka Okita, Yuki Etani, Makoto Hirao, Wataru Yamamoto, Motomu Hashimoto, Koichi Murata, Akira Onishi, Sadao Jinno, Ryota Hara, Yonsu Son, Hideki Amuro, Takuya Kotani, Hideyuki Shiba, Masaki Katayama, Keiichi Yamamoto, Atsushi Kumanogoh, Seiji Okada, Ken Nakata

Modern rheumatology　2022年8月13日　研究論文（学術雑誌）

A case of relapsing polychondritis localized to the laryngeal cartilage in which FDG-PET/CT was helpful for diagnosis

D Nakatsubo, Y Maeda, K Hosokawa, S Kawada, M Okamoto, H Shimagami, T Tada, H Kiyokawa, K Sato, S Tahara, E Morii, M Narazaki, A Kumanogoh

Scandinavian Journal of Rheumatology　Vol. 52　No. 1　p. 102-104　2022年8月10日　研究論文（学術雑誌）

Safety and immunogenicity of a quadrivalent seasonal influenza vaccine adjuvanted with hydroxypropyl-β-cyclodextrin: A phase 1 clinical trial.

Akane Watanabe, Sumiyuki Nishida, Temizöz Burcu, Takayuki Shibahara, Takato Kusakabe, Etsushi Kuroda, Ken J Ishii, Atsushi Kumanogoh

Vaccine　Vol. 40　No. 31　p. 4150-4159　2022年7月29日　研究論文（学術雑誌）

Lateral Decubitus Position Enables Further Advancement of the Bronchoscope into the Lung Periphery.

Kotaro Miyake, Takayuki Shiroyama, Haruhiko Hirata, Izumi Nagatomo, Yoshito Takeda, Atsushi Kumanogoh

Journal of bronchology & interventional pulmonology　Vol. 29　No. 4　p. 307-310　2022年7月26日　研究論文（学術雑誌）

CpG ODN (K3)-toll-like receptor 9 agonist-induces Th1-type immune response and enhances cytotoxic activity in advanced lung cancer patients: a phase I study.

Tomoyuki Otsuka, Sumiyuki Nishida, Takayuki Shibahara, Burcu Temizoz, Masanari Hamaguchi, Takayuki Shiroyama, Keiko Kimura, Kotaro Miyake, Haruhiko Hirata, Yumiko Mizuno, Mayu Yagita, Yusuke Manabe, Etsushi Kuroda, Yoshito Takeda, Hiroshi Kida, Ken J Ishii, Atsushi Kumanogoh

BMC cancer　Vol. 22　No. 1　p. 744-744　2022年7月7日　研究論文（学術雑誌）

Respiratory Impedance is Associated with Ventilation and Diffusing Capacity in Patients with Idiopathic Pulmonary Fibrosis Combined with Emphysema

Yuji Yamamoto, Haruhiko Hirata, Takayuki Shiroyama, Tomoki Kuge, Kinnosuke Matsumoto, Midori Yoneda, Makoto Yamamoto, Yujiro Naito, Yasuhiko Suga, Kiyoharu Fukushima, Kotaro Miyake, Shohei Koyama, Kota Iwahori, Izumi Nagatomo, Yoshito Takeda, Atsushi Kumanogoh

International Journal of Chronic Obstructive Pulmonary Disease　Vol. Volume 17　p. 1495-1506　2022年7月　研究論文（学術雑誌）

Impact of the Treatment Line on the Risks and Benefits of Immune Checkpoint Inhibitors in Patients With Non-Small Cell Lung Cancer and Interstitial Lung Disease.

Kinnosuke Matsumoto, Takayuki Shiroyama, Yuji Yamamoto, Kotaro Miyake, Yoshito Takeda, Atsushi Kumanogoh

Chest　Vol. 162　No. 1　2022年7月

Chronic Pulmonary Disease Caused by Tsukamurella toyonakaense.

Tomoki Kuge, Kiyoharu Fukushima, Yuki Matsumoto, Haruko Saito, Yuko Abe, Eri Akiba, Kako Haduki, Tadayoshi Nitta, Akira Kawano, Michio Tanaka, Yumi Hattori, Takahiro Kawasaki, Takanori Matsuki, Takayuki Shiroyama, Daisuke Motooka, Kazuyuki Tsujino, Keisuke Miki, Masahide Mori, Seigo Kitada, Shota Nakamura, Tetsuya Iida, Atsushi Kumanogoh, Hiroshi Kida

Emerging infectious diseases　Vol. 28　No. 7　p. 1437-1441　2022年7月　研究論文（学術雑誌）

Multi-trait and cross-population genome-wide association studies across autoimmune and allergic diseases identify shared and distinct genetic component

Yuya Shirai, Yoshimitsu Nakanishi, Akari Suzuki, Hachirou Konaka, Rika Nishikawa, Kyuto Sonehara, Shinichi Namba, Hiroaki Tanaka, Tatsuo Masuda, Moto Yaga, Shingo Satoh, Mayuko Izumi, Yumiko Mizuno, Tatsunori Jo, Yuichi Maeda, Takuro Nii, Eri Oguro-Igashira, Takayuki Morisaki, Yoichiro Kamatani, Shingo Nakayamada, Chikako Nishigori, Yoshiya Tanaka, Yoshito Takeda, Kazuhiko Yamamoto, Atsushi Kumanogoh, Yukinori Okada

Annals of the Rheumatic Diseases　Vol. 81　No. 9　p. annrheumdis-2022　2022年6月26日　研究論文（学術雑誌）

Longitudinal alterations of the gut mycobiota and microbiota on COVID-19 severity.

Yuichi Maeda, Daisuke Motooka, Takahiro Kawasaki, Hiroya Oki, Yoshimi Noda, Yuichi Adachi, Takayuki Niitsu, Shota Okamoto, Kentaro Tanaka, Kiyoharu Fukushima, Saori Amiya, Reina Hara, Eri Oguro-Igashira, Takanori Matsuki, Haruhiko Hirata, Yoshito Takeda, Hiroshi Kida, Atsushi Kumanogoh, Shota Nakamura, Kiyoshi Takeda

BMC infectious diseases　Vol. 22　No. 1　p. 572-572　2022年6月24日　研究論文（学術雑誌）

Genome-Wide Association Study of Intracranial Artery Stenosis Followed by Phenome-Wide Association Study.

Shogo Dofuku, Kyuto Sonehara, Satoru Miyawaki, Saori Sakaue, Hideaki Imai, Masahiro Shimizu, Hiroki Hongo, Yuki Shinya, Kenta Ohara, Yu Teranishi, Atsushi Okano, Hideaki Ono, Hirofumi Nakatomi, Akira Teraoka, Kenichi Yamamoto, Yuichi Maeda, Takuro Nii, Toshihiro Kishikawa, Ken Suzuki, Jun Hirata, Meiko Takahashi, Koichi Matsuda, Atsushi Kumanogoh, Fumihiko Matsuda, Yukinori Okada, Nobuhito Saito

Translational stroke research　2022年6月14日　研究論文（学術雑誌）

Identification of CD14 and lipopolysaccharide-binding protein as novel biomarkers for sarcoidosis using proteomics of serum extracellular vesicles.

Yu Futami, Yoshito Takeda, Taro Koba, Ryohei Narumi, Yosui Nojima, Mari Ito, Mana Nakayama, Mimiko Ishida, Hanako Yoshimura, Yujiro Naito, Kiyoharu Fukushima, Takayuki Takimoto, Ryuya Edahiro, Takanori Matsuki, Satoshi Nojima, Haruhiko Hirata, Shohei Koyama, Kota Iwahori, Izumi Nagatomo, Yuya Shirai, Yasuhiko Suga, Shingo Satoh, Shinji Futami, Kotaro Miyake, Takayuki Shiroyama, Yoshikazu Inoue, Jun Adachi, Takeshi Tomonaga, Koji Ueda, Atsushi Kumanogoh

International immunology　Vol. 34　No. 6　p. 327-340　2022年6月4日　研究論文（学術雑誌）

Duration of SARS-CoV-2 RNA positivity from various specimens and clinical characteristics in patients with COVID-19: a systematic review and meta-analysis.

Yasutaka Okita, Takayoshi Morita, Atsushi Kumanogoh

Inflammation and regeneration　Vol. 42　No. 1　p. 16-16　2022年6月1日　研究論文（学術雑誌）

Quantitative evaluation of emphysema for predicting immunotherapy response in patients with advanced non-small-cell lung cancer.

Yoshimi Noda, Takayuki Shiroyama, Kentaro Masuhiro, Saori Amiya, Takatoshi Enomoto, Yuichi Adachi, Reina Hara, Takayuki Niitsu, Yujiro Naito, Kotaro Miyake, Shohei Koyama, Haruhiko Hirata, Izumi Nagatomo, Yoshito Takeda, Atsushi Kumanogoh

Scientific reports　Vol. 12　No. 1　p. 8881-8881　2022年5月25日　研究論文（学術雑誌）

Leucine-rich a-2 glycoprotein as a potential biomarker of idiopathic multicentric Castleman disease with pulmonary involvement: a single-center case-control study from Japan.

So Takata, Yoshito Takeda, Haruhiko Hirata, Yuya Shirai, Takayoshi Morita, Yu Futami, Yujiro Naito, Kentaro Masuhiro, Takayuki Shiroyama, Kotaro Miyake, Tetsuji Naka, Atsushi Kumanogoh

Journal of thoracic disease　Vol. 14　No. 5　p. 1332-1341　2022年5月　研究論文（学術雑誌）

Cell-Free DNA Derived From Neutrophils Triggers Type 1 Interferon Signature in Neuromyelitis Optica Spectrum Disorder.

Hisashi Murata, Makoto Kinoshita, Yoshiaki Yasumizu, Daisuke Motooka, Shohei Beppu, Naoyuki Shiraishi, Yasuko Sugiyama, Keigo Kihara, Satoru Tada, Toru Koda, Hachiro Konaka, Hyota Takamatsu, Atsushi Kumanogoh, Tatsusada Okuno, Hideki Mochizuki

Neurology(R) neuroimmunology & neuroinflammation　Vol. 9　No. 3　2022年5月　研究論文（学術雑誌）

Bronchoalveolar lavage fluid reveals factors contributing to the efficacy of PD-1 blockade in lung cancer.

Kentaro Masuhiro, Motohiro Tamiya, Kosuke Fujimoto, Shohei Koyama, Yujiro Naito, Akio Osa, Takashi Hirai, Hidekazu Suzuki, Norio Okamoto, Takayuki Shiroyama, Kazumi Nishino, Yuichi Adachi, Takuro Nii, Yumi Kinugasa-Katayama, Akiko Kajihara, Takayoshi Morita, Seiya Imoto, Satoshi Uematsu, Takuma Irie, Daisuke Okuzaki, Taiki Aoshi, Yoshito Takeda, Toru Kumagai, Tomonori Hirashima, Atsushi Kumanogoh

JCI insight　Vol. 7　No. 9　2022年4月7日　研究論文（学術雑誌）

Rapid attenuation of anti-SARS-CoV-2 antibodies in patients with musculoskeletal diseases in whom intensive immunosuppressive therapies were reinitiated after COVID-19: comment on the article by Curtis et al.

Masashi Okamoto, Shoji Kawada, Hiroshi Shimagami, Naoko Fujii, Kazuki Matsukawa, Nachi Ishikawa, Keisuke Kawamoto, Shinji Higa, Yutaka Ishida, Atsushi Ogata, Yuta Yamaguchi, Takayoshi Morita, Yasuhiro Kato, Atsushi Kumanogoh

Arthritis & rheumatology (Hoboken, N.J.)　Vol. 74　No. 4　p. 726-728　2022年4月　研究論文（学術雑誌）

The superiority of manual over automated methods in identifying bronchial trees on identical CT images.

So Takata, Kotaro Miyake, Atsushi Kumanogoh

Scientific reports　Vol. 12　No. 1　p. 5416-5416　2022年3月30日　研究論文（学術雑誌）

Data-driven patient stratification and drug target discovery by using medical information and serum proteome data of idiopathic pulmonary fibrosis patients

Yayoi Natsume-Kitatani, Mari N Itoh, Yoshito Takeda, Masataka Kuroda, Haruhiko Hirata, Kohtaro Miyake, Takayuki Shiroyama, Yuya Shirai, Yoshimi Noda, Yuichi Adachi, Takatoshi Enomoto, Saori Amiya, Jun Adachi, Ryohei Narumi, Satoshi Muraoka, Takeshi Tomonaga, Sadao Kurohashi, Fei Cheng, Ribeka Tanaka, Shuntaro Yada, Eiji Aramaki, Shoko Wakamiya, Yi-An Chen, Chihiro Higuchi, Yosui Nojima, Takeshi Fujiwara, Chioko Nagao, Yasushi Matsumura, Kenji Mizuguchi, Atsushi Kumanogoh, Naonori Ueda

2022年3月29日

Marked increase of interferon-β after BNT162b2 mRNA vaccination: a case of polyarthritis with pleurisy.

Hiroshi Shimagami, Yuta Yamaguchi, Yasuhiro Kato, Atsushi Kumanogoh

BMJ case reports　Vol. 15　No. 3　2022年3月2日　研究論文（学術雑誌）

Anterior chamber flare and ciliochoroidal detachment using flare photometry and anterior segment optical coherence tomography in acute lupus choroidopathy: A case report.

Satoko Fujimoto, Taku Wakabayashi, Kazuichi Maruyama, Chikako Hara, Eri Oguro-Igashira, Masayuki Nishide, Hirokazu Sakaguchi, Atsushi Kumanogoh, Kohji Nishida

American journal of ophthalmology case reports　Vol. 25　p. 101314-101314　2022年3月

Cellular Adhesion Is a Controlling Factor in Neutrophil Extracellular Trap Formation Induced by Anti-Neutrophil Cytoplasmic Antibodies.

Patrick M Lelliott, Masayuki Nishide, Nicolas Pavillon, Yasutaka Okita, Takayuki Shibahara, Yumiko Mizuno, Hanako Yoshimura, Sho Obata, Atsushi Kumanogoh, Nicholas I Smith

ImmunoHorizons　Vol. 6　No. 2　p. 170-183　2022年2月22日　研究論文（学術雑誌）

Selective targeting of multiple myeloma cells with a monoclonal antibody recognizing the ubiquitous protein CD98 heavy chain.

Kana Hasegawa, Shunya Ikeda, Moto Yaga, Kouki Watanabe, Rika Urakawa, Akie Iehara, Mai Iwai, Seishin Hashiguchi, Soyoko Morimoto, Fumihiro Fujiki, Hiroko Nakajima, Jun Nakata, Sumiyuki Nishida, Akihiro Tsuboi, Yoshihiro Oka, Satoshi Yoshihara, Masahiro Manabe, Hiroyoshi Ichihara, Atsuko Mugitani, Yasutaka Aoyama, Takafumi Nakao, Asao Hirose, Masayuki Hino, Shiho Ueda, Katsuto Takenaka, Takashi Masuko, Koichi Akashi, Takahiro Maruno, Susumu Uchiyama, Shinji Takamatsu, Naoki Wada, Eiichi Morii, Shushi Nagamori, Daisuke Motooka, Yoshikatsu Kanai, Yusuke Oji, Tomoyoshi Nakagawa, Noriyuki Kijima, Haruhiko Kishima, Atsuyo Ikeda, Takayuki Ogino, Yasushi Shintani, Tateki Kubo, Emiko Mihara, Kosuke Yusa, Haruo Sugiyama, Junichi Takagi, Eiji Miyoshi, Atsushi Kumanogoh, Naoki Hosen

Science translational medicine　Vol. 14　No. 632　2022年2月16日　研究論文（学術雑誌）

Corrigendum to "Cell surface-expressed Ro52/IgG/HLA-DR complex is targeted by autoantibodies in patients with inflammatory myopathies" [J. Autoimmun. 126 (2022) 102774].

Noriko Arase, Hideaki Tsuji, Hyota Takamatsu, Hui Jin, Hachiro Konaka, Yasuhito Hamaguchi, Kyoko Tonomura, Yorihisa Kotobuki, Ikuko Ueda-Hayakawa, Sumiko Matsuoka, Toru Hirano, Hideki Yorifuji, Hiroyuki Murota, Koichiro Ohmura, Ran Nakashima, Tomoharu Sato, Atsushi Kumanogoh, Ichiro Katayama, Hisashi Arase, Manabu Fujimoto

Journal of autoimmunity　Vol. 127　p. 102797-102797　2022年2月9日

COVID-19 in a human T-cell lymphotropic virus type-1 carrier.

Takatoshi Enomoto, Takayuki Shiroyama, Haruhiko Hirata, Saori Amiya, Yuichi Adachi, Takayuki Niitsu, Yoshimi Noda, Reina Hara, Kiyoharu Fukushima, Yasuhiko Suga, Kotaro Miyake, Shohei Koyama, Kota Iwahori, Izumi Nagatomo, Natsuko Tokuhira, Akinori Uchiyama, Yoshito Takeda, Atsushi Kumanogoh

Clinical case reports　Vol. 10　No. 2　2022年2月

Whole gut virome analysis of 476 Japanese revealed a link between phage and autoimmune disease.

Yoshihiko Tomofuji, Toshihiro Kishikawa, Yuichi Maeda, Kotaro Ogawa, Takuro Nii, Tatsusada Okuno, Eri Oguro-Igashira, Makoto Kinoshita, Kenichi Yamamoto, Kyuto Sonehara, Mayu Yagita, Akiko Hosokawa, Daisuke Motooka, Yuki Matsumoto, Hidetoshi Matsuoka, Maiko Yoshimura, Shiro Ohshima, Shota Nakamura, Hidenori Inohara, Hideki Mochizuki, Kiyoshi Takeda, Atsushi Kumanogoh, Yukinori Okada

Annals of the rheumatic diseases　Vol. 81　No. 2　p. 278-288　2022年2月　研究論文（学術雑誌）

Axon guidance molecules in immunometabolic diseases.

Yoshimitsu Nakanishi, Sujin Kang, Atsushi Kumanogoh

Inflammation and regeneration　Vol. 42　No. 1　p. 5-5　2022年1月19日　研究論文（学術雑誌）

Case report: Acute exacerbation of interstitial pneumonia related to messenger RNA COVID-19 vaccination.

Saori Amiya, Jun Fujimoto, Kinnosuke Matsumoto, Makoto Yamamoto, Yuji Yamamoto, Midori Yoneda, Tomoki Kuge, Kotaro Miyake, Takayuki Shiroyama, Haruhiko Hirata, Yoshito Takeda, Atsushi Kumanogoh

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases　Vol. 116　p. 255-257　2022年1月19日

Degradation of the NOTCH intracellular domain by elevated autophagy in osteoblasts promotes osteoblast differentiation and alleviates osteoporosis.

Gota Yoshida, Tsuyoshi Kawabata, Hyota Takamatsu, Shotaro Saita, Shuhei Nakamura, Keizo Nishikawa, Mari Fujiwara, Yusuke Enokidani, Tadashi Yamamuro, Keisuke Tabata, Maho Hamasaki, Masaru Ishii, Atsushi Kumanogoh, Tamotsu Yoshimori

Autophagy　p. 1-10　2022年1月13日　研究論文（学術雑誌）

Factors affecting drug retention of Janus kinase inhibitors in patients with rheumatoid arthritis: the ANSWER cohort study.

Kosuke Ebina, Toru Hirano, Yuichi Maeda, Wataru Yamamoto, Motomu Hashimoto, Koichi Murata, Akira Onishi, Sadao Jinno, Ryota Hara, Yonsu Son, Hideki Amuro, Tohru Takeuchi, Ayaka Yoshikawa, Masaki Katayama, Keiichi Yamamoto, Yasutaka Okita, Makoto Hirao, Yuki Etani, Atsushi Kumanogoh, Seiji Okada, Ken Nakata

Scientific reports　Vol. 12　No. 1　p. 134-134　2022年1月7日　研究論文（学術雑誌）

Management of severe hypertension due to lenvatinib in patients with advanced thymic carcinoma: A case report.

Kinnosuke Matsumoto, Takayuki Shiroyama, Kotaro Miyake, Yuji Yamamoto, Tomoki Kuge, Midori Yoneda, Makoto Yamamoto, Yujiro Naito, Yasuhiko Suga, Kiyoharu Fukushima, Shohei Koyama, Kota Iwahori, Haruhiko Hirata, Izumi Nagatomo, Yoshito Takeda, Atsushi Kumanogoh

Medicine　Vol. 101　No. 1　2022年1月7日　研究論文（学術雑誌）

Heterogeneity of Stroke in Patients with Systemic Lupus Erythematosus.

Takaya Kitano, Toru Hirano, Shuhei Okazaki, Eri Itotagawa, Yoshiki Yagita, Yoshitaka Morita, Akihiro Watanabe, Daisuke Takahashi, Manabu Sakaguchi, Hiroshi Fujiwara, Kenichi Todo, Tsutomu Sasaki, Atsushi Kumanogoh, Hideki Mochizuki

Internal medicine (Tokyo, Japan)　Vol. 61　No. 20　p. 3045-3052　2022年　研究論文（学術雑誌）

T Cell-Intrinsic Vitamin A Metabolism and Its Signaling Are Targets for Memory T Cell-Based Cancer Immunotherapy.

Fumihiro Fujiki, Soyoko Morimoto, Akiko Katsuhara, Akane Okuda, Saeka Ogawa, Eriko Ueda, Maki Miyazaki, Ayako Isotani, Masahito Ikawa, Sumiyuki Nishida, Hiroko Nakajima, Akihiro Tsuboi, Yoshihiro Oka, Jun Nakata, Naoki Hosen, Atsushi Kumanogoh, Yusuke Oji, Haruo Sugiyama

Frontiers in immunology　Vol. 13　p. 935465-935465　2022年　研究論文（学術雑誌）

Tetracyclines Enhance Anti-tumor T-Cell Responses Induced by a Bispecific T-Cell Engager.

Yuki Noguchi, Yoko Yamamoto, Kota Iwahori, Mitsunobu Matsumoto, Michinari Hirata, Hiroomi Okuyama, Yasushi Shintani, Atsushi Kumanogoh, Hisashi Wada

Biological & pharmaceutical bulletin　Vol. 45　No. 4　p. 429-437　2022年　研究論文（学術雑誌）

A case of synchronous triple autoimmune disorders secondary to thymoma: Pure red cell aplasia, Good's syndrome, and thymoma-associated multi-organ autoimmunity.

Yuta Nakagawa, Kinnosuke Matsumoto, Makoto Yamamoto, Haruhiko Hirata, Takayuki Shiroyama, Kotaro Miyake, Yuji Yamamoto, Tomoki Kuge, Midori Yoneda, Yujiro Naito, Yasuhiko Suga, Kiyoharu Fukushima, Shohei Koyama, Kota Iwahori, Izumi Nagatomo, Yoshito Takeda, Atsushi Kumanogoh

Respiratory medicine case reports　Vol. 36　p. 101619-101619　2022年　研究論文（学術雑誌）

Continuous Use of Etanercept During Pregnancy Does Not Affect TNF-Alpha Levels in Umbilical Cord Blood.

Masayuki Nishide, Mayu Yagita, Atsushi Kumanogoh

Biologics : targets & therapy　Vol. 16　p. 17-19　2022年　研究論文（学術雑誌）

Anti-Myxovirus Resistance Protein-1 Immunoglobulin A Autoantibody in Idiopathic Pulmonary Fibrosis.

Toru Arai, Masaki Hirose, Yoshimasa Hamano, Tomoko Kagawa, Akihiro Murakami, Hiroshi Kida, Atsushi Kumanogoh, Yoshikazu Inoue

Canadian respiratory journal　Vol. 2022　p. 1107673-1107673　2022年　研究論文（学術雑誌）

Cellular and Humoral Immune Responses Induced by an HLA Class I-restricted Peptide Cancer Vaccine Targeting WT1 Are Associated With Favorable Clinical Outcomes in Advanced Ovarian Cancer.

Sumiyuki Nishida, Soyoko Morimoto, Yusuke Oji, Satoshi Morita, Toshiaki Shirakata, Takayuki Enomoto, Akihiro Tsuboi, Yutaka Ueda, Kiyoshi Yoshino, Alzaaqi Shouq, Mizuki Kanegae, Satoshi Ohno, Fumihiro Fujiki, Hiroko Nakajima, Yoshiki Nakae, Jun Nakata, Naoki Hosen, Atsushi Kumanogoh, Yoshihiro Oka, Tadashi Kimura, Haruo Sugiyama

Journal of immunotherapy (Hagerstown, Md. : 1997)　Vol. 45　No. 1　p. 56-66　2022年1月1日　研究論文（学術雑誌）

Cell surface-expressed Ro52/IgG/HLA-DR complex is targeted by autoantibodies in patients with inflammatory myopathies.

Noriko Arase, Hideaki Tsuji, Hyota Takamatsu, Hui Jin, Hachiro Konaka, Yasuhito Hamaguchi, Kyoko Tonomura, Yorihisa Kotobuki, Ikuko Ueda-Hayakawa, Sumiko Matsuoka, Toru Hirano, Hideki Yorifuji, Hiroyuki Murota, Koichiro Ohmura, Ran Nakashima, Tomoharu Sato, Atsushi Kumanogoh, Ichiro Katayama, Hisashi Arase, Manabu Fujimoto

Journal of autoimmunity　Vol. 126　p. 102774-102774　2022年1月　研究論文（学術雑誌）

Crosstalk between axon guidance signaling and bone remodeling.

Yoshimitsu Nakanishi, Sujin Kang, Atsushi Kumanogoh

Bone　Vol. 157　p. 116305-116305　2021年12月29日　研究論文（学術雑誌）

Advances and Challenges of Antibody Therapeutics for Severe Bronchial Asthma.

Yuko Abe, Yasuhiko Suga, Kiyoharu Fukushima, Hayase Ohata, Takayuki Niitsu, Hiroshi Nabeshima, Yasuharu Nagahama, Hiroshi Kida, Atsushi Kumanogoh

International journal of molecular sciences　Vol. 23　No. 1　2021年12月22日　研究論文（学術雑誌）

Genetic architecture of microRNA expression and its link to complex diseases in the Japanese population.

Kyuto Sonehara, Saori Sakaue, Yuichi Maeda, Jun Hirata, Toshihiro Kishikawa, Kenichi Yamamoto, Hidetoshi Matsuoka, Maiko Yoshimura, Takuro Nii, Shiro Ohshima, Atsushi Kumanogoh, Yukinori Okada

Human molecular genetics　Vol. 31　No. 11　p. 1806-1820　2021年12月17日　研究論文（学術雑誌）

Lipoid Pneumonia After Pembrolizumab Treatment for Advanced Non-Small-Cell Lung Cancer.

Moto Yaga, Takayuki Shiroyama, Haruhiko Hirata, Kaori Oya, Yoshito Takeda, Atsushi Kumanogoh

Clinical lung cancer　2021年12月10日

Identification of conserved SARS-CoV-2 spike epitopes that expand public cTfh clonotypes in mild COVID-19 patients.

Xiuyuan Lu, Yuki Hosono, Masamichi Nagae, Shigenari Ishizuka, Eri Ishikawa, Daisuke Motooka, Yuki Ozaki, Nicolas Sax, Yuichi Maeda, Yasuhiro Kato, Takayoshi Morita, Ryo Shinnakasu, Takeshi Inoue, Taishi Onodera, Takayuki Matsumura, Masaharu Shinkai, Takashi Sato, Shota Nakamura, Shunsuke Mori, Teru Kanda, Emi E Nakayama, Tatsuo Shioda, Tomohiro Kurosaki, Kiyoshi Takeda, Atsushi Kumanogoh, Hisashi Arase, Hironori Nakagami, Kazuo Yamashita, Yoshimasa Takahashi, Sho Yamasaki

The Journal of experimental medicine　Vol. 218　No. 12　2021年12月6日　研究論文（学術雑誌）

Impact of treatment timing and sequence of immune checkpoint inhibitors and anti-angiogenic agents for advanced non-small cell lung cancer: A systematic review and meta-analysis.

Kinnosuke Matsumoto, Takayuki Shiroyama, Tomoki Kuge, Kotaro Miyake, Yuji Yamamoto, Midori Yoneda, Makoto Yamamoto, Yujiro Naito, Yasuhiko Suga, Kiyoharu Fukushima, Shohei Koyama, Kota Iwahori, Haruhiko Hirata, Izumi Nagatomo, Yoshito Takeda, Atsushi Kumanogoh

Lung cancer (Amsterdam, Netherlands)　Vol. 162　p. 175-184　2021年12月　研究論文（学術雑誌）

Highly immunogenic cancer cells require activation of the WNT pathway for immunological escape.

Yoshiko Takeuchi, Tokiyoshi Tanegashima, Eiichi Sato, Takuma Irie, Atsuo Sai, Kota Itahashi, Shogo Kumagai, Yasuko Tada, Yosuke Togashi, Shohei Koyama, Esra A Akbay, Takahiro Karasaki, Keisuke Kataoka, Soichiro Funaki, Yasushi Shintani, Izumi Nagatomo, Hiroshi Kida, Genichiro Ishii, Tomohiro Miyoshi, Keiju Aokage, Kazuhiro Kakimi, Seishi Ogawa, Meinoshin Okumura, Masatoshi Eto, Atsushi Kumanogoh, Masahiro Tsuboi, Hiroyoshi Nishikawa

Science immunology　Vol. 6　No. 65　2021年11月12日　研究論文（学術雑誌）

Comprehensive and long-term surveys of COVID-19 sequelae in Japan, an ambidirectional multicentre cohort study: study protocol.

Kensuke Nakagawara, Ho Namkoong, Hideki Terai, Katsunori Masaki, Takae Tanosaki, Kyoko Shimamoto, Ho Lee, Hiromu Tanaka, Satoshi Okamori, Hiroki Kabata, Shotaro Chubachi, Shinnosuke Ikemura, Hirofumi Kamata, Hiroyuki Yasuda, Ichiro Kawada, Makoto Ishii, Yoshiki Ishibashi, Sei Harada, Takanori Fujita, Daisuke Ito, Shogyoku Bun, Hajime Tabuchi, Sho Kanzaki, Eisuke Shimizu, Keitaro Fukuda, Jun Yamagami, Keigo Kobayashi, Toshiyuki Hirano, Takashi Inoue, Junko Kagyo, Tetsuya Shiomi, Keiko Ohgino, Koichi Sayama, Kengo Otsuka, Naoki Miyao, Toshio Odani, Yoshitaka Oyamada, Keita Masuzawa, Sohei Nakayama, Yusuke Suzuki, Rie Baba, Ichiro Nakachi, Naota Kuwahara, Takashi Ishiguro, Shuko Mashimo, Naoto Minematsu, Soichiro Ueda, Tadashi Manabe, Yohei Funatsu, Hidefumi Koh, Takashi Yoshiyama, Fumitake Saito, Kota Ishioka, Saeko Takahashi, Morio Nakamura, Ai Goto, Norihiro Harada, Yu Kusaka, Yasushi Nakano, Kazumi Nishio, Hiroki Tateno, Ryuya Edahiro, Yoshito Takeda, Atsushi Kumanogoh, Nobuhiro Kodama, Masaki Okamoto, Akira Umeda, Kazuto Hagimura, Toshiro Sato, Naoki Miyazaki, Ryo Takemura, Yasunori Sato, Toru Takebayashi, Jin Nakahara, Masaru Mimura, Kaoru Ogawa, Shigeto Shimmura, Kazuno Negishi, Kazuo Tsubota, Masayuki Amagai, Rei Goto, Yoko Ibuka, Naoki Hasegawa, Yuko Kitagawa, Takanori Kanai, Koichi Fukunaga

BMJ open respiratory research　Vol. 8　No. 1　2021年11月　研究論文（学術雑誌）

Prolonged corticosteroid therapy and cytomegalovirus infection in patients with severe COVID-19.

Yuji Yamamoto, Takayuki Shiroyama, Haruhiko Hirata, Tomoki Kuge, Kinnosuke Matsumoto, Midori Yoneda, Makoto Yamamoto, Akinori Uchiyama, Yoshito Takeda, Atsushi Kumanogoh

Journal of medical virology　2021年10月28日　研究論文（学術雑誌）

エクソソームのプロテオミクスを用いた小細胞肺癌における新規バイオマーカー探索

菅 泰彦, 吉村 華子, 内藤 祐二郎, 白山 敬之, 三宅 浩太郎, 平田 陽彦, 小山 正平, 岩堀 幸太, 長友 泉, 武田 吉人, 熊ノ郷 淳

肺癌　Vol. 61　No. 6　p. 683-683　2021年10月

Cytomegalovirus infection in critically ill patients with COVID-19.

Takayuki Niitsu, Takayuki Shiroyama, Haruhiko Hirata, Yoshimi Noda, Yuichi Adachi, Takatoshi Enomoto, Reina Hara, Saori Amiya, Akinori Uchiyama, Yoshito Takeda, Atsushi Kumanogoh

The Journal of infection　Vol. 83　No. 4　p. 496-522　2021年10月

Opposite response of lung adenocarcinoma and its choroidal metastases upon ramucirumab plus docetaxel therapy after immunotherapy: a case report.

Kinnosuke Matsumoto, Takayuki Shiroyama, Noriyasu Hashida, Kotaro Miyake, Yuji Yamamoto, Tomoki Kuge, Midori Yoneda, Makoto Yamamoto, Yujiro Naito, Yasuhiko Suga, Kiyoharu Fukushima, Shohei Koyama, Kota Iwahori, Haruhiko Hirata, Izumi Nagatomo, Yoshito Takeda, Atsushi Kumanogoh

Angiogenesis　Vol. 25　No. 2　p. 147-149　2021年9月30日

Proximal heat stress up-regulates angiopoietin-1 in fingers and reduces the severity of Raynaud's phenomenon in systemic sclerosis: a single-centre pilot study.

Yoshihito Shima, Akane Watanabe, Nobuto Inoue, Tetsuya Maruyama, Eiji Kunitomo, Kunihiko Hamano, Takashi Kawanishi, Masashi Takasugi, Atsushi Kumanogoh

Modern rheumatology　Vol. 32　No. 2　p. 351-357　2021年9月4日　研究論文（学術雑誌）

IL-33 Induces Sema4A Expression in Dendritic Cells and Exerts Antitumor Immunity.

Yasuhiko Suga, Izumi Nagatomo, Yuhei Kinehara, Shohei Koyama, Daisuke Okuzaki, Akio Osa, Yujiro Naito, Hyota Takamatsu, Masayuki Nishide, Satoshi Nojima, Daisuke Ito, Takeshi Tsuda, Takeshi Nakatani, Yoshimitsu Nakanishi, Yu Futami, Taro Koba, Shingo Satoh, Yuki Hosono, Kotaro Miyake, Kiyoharu Fukushima, Takayuki Shiroyama, Kota Iwahori, Haruhiko Hirata, Yoshito Takeda, Atsushi Kumanogoh

Journal of immunology (Baltimore, Md. : 1950)　Vol. 207　No. 5　p. 1456-1467　2021年9月1日　研究論文（学術雑誌）

The SARS-CoV-2 Delta variant is poised to acquire complete resistance to wild-type spike vaccines

Yafei Liu, Noriko Arase, Jun-ichi Kishikawa, Mika Hirose, Songling Li, Asa Tada, Sumiko Matsuoka, Akemi Arakawa, Kanako Akamatsu, Chikako Ono, Hui Jin, Kazuki Kishida, Wataru Nakai, Masako Kohyama, Atsushi Nakagawa, Yoshiaki Yamagishi, Hironori Nakagami, Atsushi Kumanogoh, Yoshiharu Matsuura, Daron M. Standley, Takayuki Kato, Masato Okada, Manabu Fujimoto, Hisashi Arase

2021年8月23日

Metagenome-wide association study revealed disease-specific landscape of the gut microbiome of systemic lupus erythematosus in Japanese.

Yoshihiko Tomofuji, Yuichi Maeda, Eri Oguro-Igashira, Toshihiro Kishikawa, Kenichi Yamamoto, Kyuto Sonehara, Daisuke Motooka, Yuki Matsumoto, Hidetoshi Matsuoka, Maiko Yoshimura, Mayu Yagita, Takuro Nii, Shiro Ohshima, Shota Nakamura, Hidenori Inohara, Kiyoshi Takeda, Atsushi Kumanogoh, Yukinori Okada

Annals of the rheumatic diseases　Vol. 80　No. 12　p. 1575-1583　2021年8月23日　研究論文（学術雑誌）

Anti-AQP4 autoantibodies promote ATP release from astrocytes and induce mechanical pain in rats.

Teruyuki Ishikura, Makoto Kinoshita, Mikito Shimizu, Yoshiaki Yasumizu, Daisuke Motooka, Daisuke Okuzaki, Kazuya Yamashita, Hisashi Murata, Shohei Beppu, Toru Koda, Satoru Tada, Naoyuki Shiraishi, Yasuko Sugiyama, Katsuichi Miyamoto, Susumu Kusunoki, Tomoyuki Sugimoto, Atsushi Kumanogoh, Tatsusada Okuno, Hideki Mochizuki

Journal of neuroinflammation　Vol. 18　No. 1　p. 181-181　2021年8月21日　研究論文（学術雑誌）

CD14 and LBP as Novel Biomarkers for Sarcoidosis by Proteomics of Extracellular Vesicles

Yu Futami, Yoshito Takeda, Taro Koba, Ryohei Narumi, Yosui Nojima, Mari Ito, Mana Nakayama, Mimiko Ishida, Hanako Yoshimura, Yujiro Naito, Kiyoharu Fukushima, Takayuki Takimoto, Ryuya Edahiro, Tomonori Matsuki, Satoshi Nojima, Haruhiko Hirata, Shohei Koyama, Kota Iwahori, Izumi Nagatomo, Yuya Shirai, Yasuhiko Suga, Shingo Satoh, Shinji Futami, Kotaro Miyake, Takayuki Shiroyama, Yoshikazu Inoue, Jun Adachi, Takeshi Tomonaga, Koji Ueda, Atsushi Kumanogoh

2021年8月19日

Drug retention of sarilumab, baricitinib, and tofacitinib in patients with rheumatoid arthritis: the ANSWER cohort study.

Kosuke Ebina, Toru Hirano, Yuichi Maeda, Wataru Yamamoto, Motomu Hashimoto, Koichi Murata, Akira Onishi, Sadao Jinno, Ryota Hara, Yonsu Son, Hideki Amuro, Tohru Takeuchi, Ayaka Yoshikawa, Masaki Katayama, Keiichi Yamamoto, Makoto Hirao, Yasutaka Okita, Atsushi Kumanogoh, Ken Nakata

Clinical rheumatology　Vol. 40　No. 7　p. 2673-2680　2021年7月　研究論文（学術雑誌）

Comparison of efficacy between anti-IL-6 receptor antibody and other biological disease-modifying antirheumatic drugs in the patients with rheumatoid arthritis who have knee joint involvement: the ANSWER cohort, retrospective study.

Yuichi Maeda, Toru Hirano, Kosuke Ebina, Ryota Hara, Motomu Hashimoto, Wataru Yamamoto, Kosaku Murakami, Takuya Kotani, Kenichiro Hata, Yonsu Son, Hideki Amuro, Akira Onishi, Sadao Jinno, Masaki Katayama, Atsushi Kumanogoh

Rheumatology international　Vol. 41　No. 7　p. 1233-1241　2021年7月　研究論文（学術雑誌）

Fatal cytomegalovirus pneumonia in a critically ill patient with COVID-19.

Saori Amiya, Haruhiko Hirata, Takayuki Shiroyama, Yuichi Adachi, Takayuki Niitsu, Yoshimi Noda, Takatoshi Enomoto, Reina Hara, Kiyoharu Fukushima, Yasuhiko Suga, Kotaro Miyake, Moe Koide, Akinori Uchiyama, Yoshito Takeda, Atsushi Kumanogoh

Respirology case reports　Vol. 9　No. 7　2021年7月

Loss of FCHSD1 leads to amelioration of chronic obstructive pulmonary disease.

Takahiro Kawasaki, Fuminori Sugihara, Kiyoharu Fukushima, Takanori Matsuki, Hiroshi Nabeshima, Tomohisa Machida, Yuichi Mitsui, Saki Fujimura, Rio Sagawa, Lee Gaheun, Kanako Kuniyoshi, Hiroki Tanaka, Masashi Narazaki, Atsushi Kumanogoh, Shizuo Akira, Takashi Satoh

Proceedings of the National Academy of Sciences of the United States of America　Vol. 118　No. 26　2021年6月29日　研究論文（学術雑誌）

Neural guidance factors as hubs of immunometabolic crosstalk.

Yoshimitsu Nakanishi, Sujin Kang, Atsushi Kumanogoh

International immunology　Vol. 33　No. 12　p. 749-754　2021年6月26日　研究論文（学術雑誌）

The lysosomal Ragulator complex plays an essential role in leukocyte trafficking by activating myosin II.

Takeshi Nakatani, Kohei Tsujimoto, JeongHoon Park, Tatsunori Jo, Tetsuya Kimura, Yoshitomo Hayama, Hachiro Konaka, Takayoshi Morita, Yasuhiro Kato, Masayuki Nishide, Shyohei Koyama, Shigeyuki Nada, Masato Okada, Hyota Takamatsu, Atsushi Kumanogoh

Nature communications　Vol. 12　No. 1　p. 3333-3333　2021年6月7日　研究論文（学術雑誌）

Imaging Assessment of Tumor Response in the Era of Immunotherapy.

Jun Nakata, Kayako Isohashi, Yoshihiro Oka, Hiroko Nakajima, Soyoko Morimoto, Fumihiro Fujiki, Yusuke Oji, Akihiro Tsuboi, Atsushi Kumanogoh, Naoya Hashimoto, Jun Hatazawa, Haruo Sugiyama

Diagnostics (Basel, Switzerland)　Vol. 11　No. 6　2021年6月5日　研究論文（学術雑誌）

Predicting recurrence of respiratory failure in critically ill patients with COVID-19: A preliminary study.

Yuichi Adachi, Takayuki Shiroyama, Yuta Yamaguchi, Teruaki Murakami, Haruhiko Hirata, Saori Amiya, Takayuki Niitsu, Yoshimi Noda, Reina Hara, Takatoshi Enomoto, Takayoshi Morita, Yasuhiro Kato, Akinori Uchiyama, Yoshito Takeda, Atsushi Kumanogoh

The Journal of infection　Vol. 82　No. 5　2021年5月

Large-scale plasma-metabolome analysis identifies potential biomarkers of psoriasis and its clinical subtypes.

Toshihiro Kishikawa, Noriko Arase, Shigeyoshi Tsuji, Yuichi Maeda, Takuro Nii, Jun Hirata, Ken Suzuki, Kenichi Yamamoto, Tatsuo Masuda, Kotaro Ogawa, Shiro Ohshima, Hidenori Inohara, Atsushi Kumanogoh, Manabu Fujimoto, Yukinori Okada

Journal of dermatological science　Vol. 102　No. 2　p. 78-84　2021年5月　研究論文（学術雑誌）

Pulmonary artery hypertension prior to the relapse of adult-onset Still's disease.

Yuki Hara, Takayoshi Morita, Katsunao Tanaka, Fusako Sera, Yasushi Sakata, Masayuki Nishide, Yuichi Maeda, Masashi Narazaki, Atsushi Kumanogoh

Respirology case reports　Vol. 9　No. 5　2021年5月

Evasion of Innate Immunity Contributes to Small Cell Lung Cancer Progression and Metastasis.

Mingrui Zhu, Yi Huang, Matthew E Bender, Luc Girard, Rahul Kollipara, Buse Eglenen-Polat, Yujiro Naito, Trisha K Savage, Kenneth E Huffman, Shohei Koyama, Atsushi Kumanogoh, John D Minna, Jane E Johnson, Esra A Akbay

Cancer research　Vol. 81　No. 7　p. 1813-1826　2021年4月1日　研究論文（学術雑誌）

Greater reductions in blood flow after anti-angiogenic treatment in non-small cell lung cancer patients are associated with shorter progression-free survival.

Daisuke Katayama, Masahiro Yanagawa, Keiko Matsunaga, Hiroshi Watabe, Tadashi Watabe, Hiroki Kato, Takashi Kijima, Yoshito Takeda, Atsushi Kumanogoh, Eku Shimosegawa, Jun Hatazawa, Noriyuki Tomiyama

Scientific reports　Vol. 11　No. 1　p. 6805-6805　2021年3月24日　研究論文（学術雑誌）

Aryl hydrocarbon receptor is essential for the pathogenesis of pulmonary arterial hypertension.

Takeshi Masaki, Makoto Okazawa, Ryotaro Asano, Tadakatsu Inagaki, Tomohiko Ishibashi, Akiko Yamagishi, Saori Umeki-Mizushima, Manami Nishimura, Yusuke Manabe, Hatsue Ishibashi-Ueda, Manabu Shirai, Hirotsugu Tsuchimochi, James T Pearson, Atsushi Kumanogoh, Yasushi Sakata, Takeshi Ogo, Tadamitsu Kishimoto, Yoshikazu Nakaoka

Proceedings of the National Academy of Sciences of the United States of America　Vol. 118　No. 11　2021年3月16日　研究論文（学術雑誌）

Radioligand Assay-Based Detection of Antibodies against SARS-CoV-2 in Hospital Workers Treating Patients with Severe COVID-19 in Japan.

Hidenori Matsunaga, Akiko Makino, Yasuhiro Kato, Teruaki Murakami, Yuta Yamaguchi, Atsushi Kumanogoh, Yuichiro Oba, Satoshi Fujimi, Tomoyuki Honda, Keizo Tomonaga

Viruses　Vol. 13　No. 2　2021年2月23日　研究論文（学術雑誌）

Genetic determinants of risk in autoimmune pulmonary alveolar proteinosis.

Saori Sakaue, Etsuro Yamaguchi, Yoshikazu Inoue, Meiko Takahashi, Jun Hirata, Ken Suzuki, Satoru Ito, Toru Arai, Masaki Hirose, Yoshinori Tanino, Takefumi Nikaido, Toshio Ichiwata, Shinya Ohkouchi, Taizou Hirano, Toshinori Takada, Satoru Miyawaki, Shogo Dofuku, Yuichi Maeda, Takuro Nii, Toshihiro Kishikawa, Kotaro Ogawa, Tatsuo Masuda, Kenichi Yamamoto, Kyuto Sonehara, Ryushi Tazawa, Konosuke Morimoto, Masahiro Takaki, Satoshi Konno, Masaru Suzuki, Keisuke Tomii, Atsushi Nakagawa, Tomohiro Handa, Kiminobu Tanizawa, Haruyuki Ishii, Manabu Ishida, Toshiyuki Kato, Naoya Takeda, Koshi Yokomura, Takashi Matsui, Masaki Watanabe, Hiromasa Inoue, Kazuyoshi Imaizumi, Yasuhiro Goto, Hiroshi Kida, Tomoyuki Fujisawa, Takafumi Suda, Takashi Yamada, Yasuomi Satake, Hidenori Ibata, Nobuyuki Hizawa, Hideki Mochizuki, Atsushi Kumanogoh, Fumihiko Matsuda, Koh Nakata, Tomomitsu Hirota, Mayumi Tamari, Yukinori Okada

Nature communications　Vol. 12　No. 1　p. 1032-1032　2021年2月15日　研究論文（学術雑誌）

Longer Prehospitalization and Preintubation Periods in Intubated Non-survivors and ECMO Patients With COVID-19: A Systematic Review and Meta-Analysis.

Kenji Funakoshi, Takayoshi Morita, Atsushi Kumanogoh

Frontiers in medicine　Vol. 8　p. 727101-727101　2021年

Pleural Effusion Caused by Mycolicibacterium mageritense in an Immunocompetent Host: A Case Report.

Takayuki Niitsu, Tomoki Kuge, Kiyoharu Fukushima, Yuki Matsumoto, Yuko Abe, Masashi Okamoto, Kako Haduki, Haruko Saito, Tadayoshi Nitta, Akira Kawano, Takanori Matsuki, Daisuke Motooka, Kazuyuki Tsujino, Keisuke Miki, Shota Nakamura, Hiroshi Kida, Atsushi Kumanogoh

Frontiers in medicine　Vol. 8　p. 797171-797171　2021年

Therapeutic efficacy of denosumab for rheumatoid arthritis: a systematic review and meta-analysis.

Mayu Yagita, Takayoshi Morita, Atsushi Kumanogoh

Rheumatology advances in practice　Vol. 5　No. 3　2021年　研究論文（学術雑誌）

Distinct difference in tumor-infiltrating immune cells between Wilms’ tumor gene 1 peptide vaccine and anti-programmed cell death-1 antibody therapies

Chisato Yokota, Jun Nakata, Koji Takano, Hiroko Nakajima, Hiromu Hayashibara, Hikaru Minagawa, Yasuyoshi Chiba, Ryuichi Hirayama, Noriyuki Kijima, Manabu Kinoshita, Yoshiko Hashii, Akihiro Tsuboi, Yoshihiro Oka, Yusuke Oji, Atsushi Kumanogoh, Haruo Sugiyama, Naoki Kagawa, Haruhiko Kishima

Neuro-Oncology Advances　Vol. 3　No. 1　2021年1月1日　研究論文（学術雑誌）

Oral intake of silica nanoparticles exacerbates intestinal inflammation.

Takao Ogawa, Ryu Okumura, Kazuya Nagano, Tomomi Minemura, Masahiro Izumi, Daisuke Motooka, Shota Nakamura, Tetsuya Iida, Yuichi Maeda, Atsushi Kumanogoh, Yasuo Tsutsumi, Kiyoshi Takeda

Biochemical and biophysical research communications　Vol. 534　p. 540-546　2021年1月1日　研究論文（学術雑誌）

Proteomics of serum extracellular vesicles identifies a novel COPD biomarker, fibulin-3 from elastic fibres.

Taro Koba, Yoshito Takeda, Ryohei Narumi, Takashi Shiromizu, Yosui Nojima, Mari Ito, Muneyoshi Kuroyama, Yu Futami, Takayuki Takimoto, Takanori Matsuki, Ryuya Edahiro, Satoshi Nojima, Yoshitomo Hayama, Kiyoharu Fukushima, Haruhiko Hirata, Shohei Koyama, Kota Iwahori, Izumi Nagatomo, Mayumi Suzuki, Yuya Shirai, Teruaki Murakami, Kaori Nakanishi, Takeshi Nakatani, Yasuhiko Suga, Kotaro Miyake, Takayuki Shiroyama, Hiroshi Kida, Takako Sasaki, Koji Ueda, Kenji Mizuguchi, Jun Adachi, Takeshi Tomonaga, Atsushi Kumanogoh

ERJ open research　Vol. 7　No. 1　2021年1月　研究論文（学術雑誌）

COVID-19 in a patient with sporadic lymphangioleiomyomatosis awaiting lung transplantation.

Yoshimi Noda, Takayuki Shiroyama, Saori Amiya, Yuichi Adachi, Takatoshi Enomoto, Reina Hara, Takayuki Niitsu, Kotaro Miyake, Haruhiko Hirata, Yoshito Takeda, Atsushi Kumanogoh

Respiratory medicine case reports　Vol. 34　p. 101505-101505　2021年

Combined small cell lung carcinoma harboring ALK rearrangement: A case report and literature review.

Takayuki Niitsu, Takayuki Shiroyama, Kotaro Miyake, Yoshimi Noda, Kansuke Kido, Reina Hara, Takatoshi Enomoto, Yuichi Adachi, Saori Amiya, Yasuhiko Suga, Kiyoharu Fukushima, Shohei Koyama, Kota Iwahori, Haruhiko Hirata, Izumi Nagatomo, Yoshito Takeda, Atsushi Kumanogoh

Thoracic cancer　Vol. 11　No. 12　p. 3625-3630　2020年12月　研究論文（学術雑誌）

PlexinA1 deficiency in BALB/cAJ mice leads to excessive self-grooming and reduced prepulse inhibition.

Mst Sharifa Jahan, Takuji Ito, Sachika Ichihashi, Takanobu Masuda, Md Eliusur Rahman Bhuiyan, Ikuko Takahashi, Hyota Takamatsu, Atsushi Kumanogoh, Takamasa Tsuzuki, Takayuki Negishi, Kazunori Yukawa

IBRO reports　Vol. 9　p. 276-289　2020年12月　研究論文（学術雑誌）

Association of the RPA3-UMAD1 locus with interstitial lung diseases complicated with rheumatoid arthritis in Japanese.

Yuya Shirai, Suguru Honda, Katsunori Ikari, Masahiro Kanai, Yoshito Takeda, Yoichiro Kamatani, Takayuki Morisaki, Eiichi Tanaka, Atsushi Kumanogoh, Masayoshi Harigai, Yukinori Okada

Annals of the rheumatic diseases　Vol. 79　No. 10　p. 1305-1309　2020年10月　研究論文（学術雑誌）

Pulmonary metastases of lung adenocarcinoma mimicking COVID-19 pneumonia.

Takayuki Shiroyama, Haruhiko Hirata, Izumi Nagatomo, Yoshito Takeda, Atsushi Kumanogoh

Journal of thoracic disease　Vol. 12　No. 10　p. 6125-6126　2020年10月　研究論文（学術雑誌）

Olig2-Induced Semaphorin Expression Drives Corticospinal Axon Retraction After Spinal Cord Injury.

Masaki Ueno, Yuka Nakamura, Hiroshi Nakagawa, Jesse K Niehaus, Mari Maezawa, Zirong Gu, Atsushi Kumanogoh, Hirohide Takebayashi, Qing Richard Lu, Masahiko Takada, Yutaka Yoshida

Cerebral cortex (New York, N.Y. : 1991)　Vol. 30　No. 11　p. 5702-5716　2020年10月1日　研究論文（学術雑誌）

Tet DNA demethylase is required for plasma cell differentiation by controlling expression levels of IRF4.

Kentaro Fujii, Shinya Tanaka, Takanori Hasegawa, Masashi Narazaki, Atsushi Kumanogoh, Haruhiko Koseki, Tomohiro Kurosaki, Wataru Ise

International immunology　Vol. 32　No. 10　p. 683-690　2020年9月30日　研究論文（学術雑誌）

Enhanced immune reaction resulting from co-vaccination of WT1 helper peptide assessed on PET-CT.

Jun Nakata, Kayako Isohashi, Soyoko Morimoto, Ryota Itou, Takashi Kamiya, Ai Matsuura, Hiroko Nakajima, Fumihiro Fujiki, Sumiyuki Nishida, Yoshiko Hasii, Kana Hasegawa, Shinichi Nakatsuka, Naoki Hosen, Akihiro Tsuboi, Yoshihiro Oka, Atsushi Kumanogoh, Masaru Shibano, Satoru Munakata, Yusuke Oji, Jun Hatazawa, Haruo Sugiyama

Medicine　Vol. 99　No. 39　2020年9月25日　研究論文（学術雑誌）

Metabolomic analysis of fibrotic mice combined with public RNA-Seq human lung data reveal potential diagnostic biomarker candidates for lung fibrosis.

Yosui Nojima, Yoshito Takeda, Yohei Maeda, Takeshi Bamba, Eiichiro Fukusaki, Mari N Itoh, Kenji Mizuguchi, Atsushi Kumanogoh

FEBS open bio　Vol. 10　No. 11　p. 2427-2436　2020年9月22日　研究論文（学術雑誌）

LRRK2 regulates endoplasmic reticulum-mitochondrial tethering through the PERK-mediated ubiquitination pathway.

Toshihiko Toyofuku, Yuki Okamoto, Takako Ishikawa, Shigemi Sasawatari, Atsushi Kumanogoh

The EMBO journal　Vol. 39　No. 18　2020年9月15日

Increased levels of plasma nucleotides in patients with rheumatoid arthritis.

Toshihiro Kishikawa, Yuichi Maeda, Takuro Nii, Noriko Arase, Jun Hirata, Ken Suzuki, Kenichi Yamamoto, Tatsuo Masuda, Kotaro Ogawa, Shigeyoshi Tsuji, Masato Matsushita, Hidetoshi Matsuoka, Maiko Yoshimura, Shinichiro Tsunoda, Shiro Ohshima, Masashi Narazaki, Atsushi Ogata, Yukihiko Saeki, Hidenori Inohara, Atsushi Kumanogoh, Kiyoshi Takeda, Yukinori Okada

International immunology　Vol. 33　No. 2　p. 119-124　2020年8月31日　研究論文（学術雑誌）

Mitochondrial DNA enhance innate immune responses in neuromyelitis optica by monocyte recruitment and activation.

Mikito Shimizu, Tatsusada Okuno, Makoto Kinoshita, Hisae Sumi, Harutoshi Fujimura, Kazuya Yamashita, Tomoyuki Sugimoto, Shuhei Sakakibara, Kaori Sakakibara, Toru Koda, Satoru Tada, Teruyuki Ishikura, Hisashi Murata, Shohei Beppu, Naoyuki Shiraishi, Yasuko Sugiyama, Yuji Nakatsuji, Atsushi Kumanogoh, Hideki Mochizuki

Scientific reports　Vol. 10　No. 1　p. 13274-13274　2020年8月6日　研究論文（学術雑誌）

Revisiting Cell Death Responses in Fibrotic Lung Disease: Crosstalk between Structured and Non-Structured Cells.

Kiyoharu Fukushima, Takashi Satoh, Hiroshi Kida, Atsushi Kumanogoh

Diagnostics (Basel, Switzerland)　Vol. 10　No. 7　2020年7月21日　研究論文（学術雑誌）

Recovery from prolonged thrombocytopenia in patients with TAFRO syndrome: case series and literature review.

Yuta Yamaguchi, Yuichi Maeda, Takayuki Shibahara, Shinichiro Nameki, Akihiko Nakabayashi, Kiyohide Komuta, Yumiko Mizuno, Mayu Yagita, Yusuke Manabe, Takayoshi Morita, Masayuki Nishide, Akane Watanabe, Hyota Takamatsu, Sumiyuki Nishida, Toru Hirano, Yoshihito Shima, Masashi Narazaki, Atsushi Kumanogoh

Modern rheumatology case reports　Vol. 4　No. 2　p. 302-309　2020年7月　研究論文（学術雑誌）

The spectrum of macrophage activation by immunometabolism.

Sujin Kang, Atsushi Kumanogoh

International immunology　Vol. 32　No. 7　p. 467-473　2020年6月26日　研究論文（学術雑誌）

Pristane/Hypoxia (PriHx) Mouse as a Novel Model of Pulmonary Hypertension Reflecting Inflammation and Fibrosis

Hiroyoshi Mori, Tomohiko Ishibashi, Tadakatsu Inagaki, Makoto Okazawa, Takeshi Masaki, Ryotaro Asano, Yusuke Manabe, Keiko Ohta-Ogo, Masashi Narazaki, Hatsue Ishibashi-Ueda, Atsushi Kumanogoh, Yoshikazu Nakaoka

Circulation Journal　Vol. 84　No. 7　p. 1163-1172　2020年6月25日　研究論文（学術雑誌）

Host Immune Response and Novel Diagnostic Approach to NTM Infections.

Yuko Abe, Kiyoharu Fukushima, Yuki Hosono, Yuki Matsumoto, Daisuke Motooka, Naoko Ose, Shota Nakamura, Seigo Kitada, Hiroshi Kida, Atsushi Kumanogoh

International journal of molecular sciences　Vol. 21　No. 12　2020年6月18日　研究論文（学術雑誌）

Drug retention of 7 biologics and tofacitinib in biologics-naïve and biologics-switched patients with rheumatoid arthritis -The ANSWER cohort study-

Ebina K, Hirano T, Maeda Y, Yamamoto W, Hashimoto M, Murata K, Takeuchi T, Shiba H, Son Y, Amuro H, Onishi A, Akashi K, Hara R, Katayama M, Yamamoto K, Kumanogoh A, Hirao M

Arthritis Research & Therapy　Vol. 22　No. 1　p. 142-142　2020年6月15日　研究論文（学術雑誌）

Efficacy of mycophenolate mofetil as a remission induction therapy in antineutrophil cytoplasmic antibody: associated vasculitis-a meta-analysis.

Kentaro Kuzuya, Takayoshi Morita, Atsushi Kumanogoh

RMD open　Vol. 6　No. 1　2020年4月　研究論文（学術雑誌）

Dysregulated Expression of the Nuclear Exosome Targeting Complex Component Rbm7 in Nonhematopoietic Cells Licenses the Development of Fibrosis.

Kiyoharu Fukushima, Takashi Satoh, Fuminori Sugihara, Yuki Sato, Toru Okamoto, Yuichi Mitsui, Sachiyo Yoshio, Songling Li, Satoshi Nojima, Daisuke Motooka, Shota Nakamura, Hiroshi Kida, Daron M Standley, Eiichi Morii, Tatsuya Kanto, Motoko Yanagita, Yoshiharu Matsuura, Takashi Nagasawa, Atsushi Kumanogoh, Shizuo Akira

Immunity　Vol. 52　No. 3　p. 542-556　2020年3月17日　研究論文（学術雑誌）

Sema4A is implicated in the acceleration of Th17 cell-mediated neuroinflammation in the effector phase.

Toru Koda, Akiko Namba, Makoto Kinoshita, Yuji Nakatsuji, Tomoyuki Sugimoto, Kaori Sakakibara, Satoru Tada, Mikito Shimizu, Kazuya Yamashita, Kazushiro Takata, Teruyuki Ishikura, Syo Murata, Shohei Beppu, Atsushi Kumanogoh, Hideki Mochizuki, Tatsusada Okuno

Journal of neuroinflammation　Vol. 17　No. 1　p. 82-82　2020年3月13日　研究論文（学術雑誌）

Drug retention of secondary biologics or JAK inhibitors after tocilizumab or abatacept failure as first biologics in patients with rheumatoid arthritis -the ANSWER cohort study.

Kosuke Ebina, Toru Hirano, Yuichi Maeda, Wataru Yamamoto, Motomu Hashimoto, Koichi Murata, Tohru Takeuchi, Koji Nagai, Yonsu Son, Hideki Amuro, Akira Onishi, Sadao Jinno, Ryota Hara, Masaki Katayama, Keiichi Yamamoto, Atsushi Kumanogoh, Makoto Hirao

Clinical rheumatology　Vol. 39　No. 9　p. 2563-2572　2020年3月11日　研究論文（学術雑誌）

Immunotherapeutic potential of CD4 and CD8 single-positive T cells in thymic epithelial tumors.

Yoko Yamamoto, Kota Iwahori, Soichiro Funaki, Mitsunobu Matsumoto, Michinari Hirata, Tetsuya Yoshida, Ryu Kanzaki, Takashi Kanou, Naoko Ose, Masato Minami, Eiichi Sato, Atsushi Kumanogoh, Yasushi Shintani, Meinoshin Okumura, Hisashi Wada

Scientific reports　Vol. 10　No. 1　p. 4064-4064　2020年3月4日　研究論文（学術雑誌）

Blockade of N-Glycosylation Promotes Antitumor Immune Response of T Cells.

Shigemi Sasawatari, Yuki Okamoto, Atsushi Kumanogoh, Toshihiko Toyofuku

Journal of immunology (Baltimore, Md. : 1950)　Vol. 204　No. 5　p. 1373-1385　2020年3月1日　研究論文（学術雑誌）

Pathological and therapeutic implications of eosinophil-derived semaphorin 4D in eosinophilic chronic rhinosinusitis.

Takeshi Tsuda, Masayuki Nishide, Yohei Maeda, Yoshitomo Hayama, Shohei Koyama, Satoshi Nojima, Hyota Takamatsu, Daisuke Okuzaki, Takayoshi Morita, Takeshi Nakatani, Yasuhiro Kato, Yoshimitsu Nakanishi, Yu Futami, Yasuhiko Suga, Yujiro Naito, Hachiro Konaka, Shingo Satoh, Maiko Naito, Mayuko Izumi, Sho Obata, Ayaka Nakatani, Takashi Shikina, Kazuya Takeda, Masaki Hayama, Hidenori Inohara, Atsushi Kumanogoh

The Journal of allergy and clinical immunology　Vol. 145　No. 3　p. 843-854　2020年3月　研究論文（学術雑誌）

Monitoring PD-1-Blocking Antibodies Bound to T Cells Derived from a Drop of Peripheral Blood.

Yujiro Naito, Akio Osa, Kentaro Masuhiro, Takashi Hirai, Shohei Koyama, Atsushi Kumanogoh

Journal of visualized experiments : JoVE　No. 156　2020年2月5日　研究論文（学術雑誌）

OCTA, a sensitive screening for asymptomatic retinopathy, raises alarm over systemic involvements in patients with SLE.

Yumiko Mizuno, Masayuki Nishide, Taku Wakabayashi, Kohji Nishida, Atsushi Kumanogoh

Annals of the rheumatic diseases　Vol. 79　No. 2　2020年2月

Severe myocarditis with slight lymphocytic infiltration after nivolumab treatment.

Edahiro R, Shiroyama T, Hijiki S, Nojima S, Shirai Y, Koyama S, Kumanogoh A

Lung cancer (Amsterdam, Netherlands)　Vol. 140　p. 116-117　2020年2月

Real-Time Monitoring and Detection of Single-Cell Level Cytokine Secretion Using LSPR Technology.

Chen Zhu, Xi Luo, Wilfred Villariza Espulgar, Shohei Koyama, Atsushi Kumanogoh, Masato Saito, Hyota Takamatsu, Eiichi Tamiya

Micromachines　Vol. 11　No. 1　2020年1月19日　研究論文（学術雑誌）

LRRK2 regulates endoplasmic reticulum-mitochondrial tethering through the PERK-mediated ubiquitination pathway.

Toyofuku T, Okamoto Y, Ishikawa T, Sasawatari S, Kumanogoh A

The EMBO journal　Vol. 39　No. 2　2020年1月15日　研究論文（学術雑誌）

Integrative Analysis Reveals Common and Unique Roles of Tetraspanins in Fibrosis and Emphysema.

Lokesh P Tripathi, Mari N Itoh, Yoshito Takeda, Kazuyuki Tsujino, Yasushi Kondo, Atsushi Kumanogoh, Kenji Mizuguchi

Frontiers in genetics　Vol. 11　p. 585998-585998　2020年　研究論文（学術雑誌）

A case of SAPHO syndrome with the lesions limited to the skull.

Eri Oguro, Yasuhiro Kato, Hyota Takamatsu, Masashi Narazaki, Atsushi Kumanogoh

Rheumatology advances in practice　Vol. 4　No. 2　2020年　研究論文（学術雑誌）

The therapeutic efficacy of denosumab for the loss of bone mineral density in glucocorticoid-induced osteoporosis: a meta-analysis.

Yuta Yamaguchi, Takayoshi Morita, Atsushi Kumanogoh

Rheumatology advances in practice　Vol. 4　No. 1　2020年　研究論文（学術雑誌）

A Microfluidic Platform for Single Cell Fluorometric Granzyme B Profiling.

Jonathan C Briones, Wilfred V Espulgar, Shohei Koyama, Hiroyuki Yoshikawa, JeongHoon Park, Yujiro Naito, Atsushi Kumanogoh, Eiichi Tamiya, Hyota Takamatsu, Masato Saito

Theranostics　Vol. 10　No. 1　p. 123-132　2020年　研究論文（学術雑誌）

Docetaxel Upregulates HMGB1 Levels in Non-small Cell Lung Cancer.

Miya Haruna, Michinari Hirata, Kota Iwahori, Takayuki Kanazawa, Yoko Yamamoto, Kumiko Goto, Atsunari Kawashima, Akiko Morimoto-Okazawa, Soichiro Funaki, Yasushi Shintani, Atsushi Kumanogoh, Hisashi Wada

Biological & pharmaceutical bulletin　Vol. 43　No. 3　p. 399-403　2020年　研究論文（学術雑誌）

Metagenome-wide association study of gut microbiome revealed novel aetiology of rheumatoid arthritis in the Japanese population.

Kishikawa T, Maeda Y, Nii T, Motooka D, Matsumoto Y, Matsushita M, Matsuoka H, Yoshimura M, Kawada S, Teshigawara S, Oguro E, Okita Y, Kawamoto K, Higa S, Hirano T, Narazaki M, Ogata A, Saeki Y, Nakamura S, Inohara H, Kumanogoh A, Takeda K, Okada Y

Annals of the rheumatic diseases　Vol. 79　No. 1　p. 103-111　2020年1月　研究論文（学術雑誌）

Lipid nanoparticles of Type-A CpG D35 suppress tumor growth by changing tumor immune-microenvironment and activate CD8 T cells in mice.

Lisa Munakata, Yoshihiko Tanimoto, Akio Osa, Jie Meng, Yasunari Haseda, Yujiro Naito, Hirotomo Machiyama, Atsushi Kumanogoh, Daiki Omata, Kazuo Maruyama, Yasuo Yoshioka, Yoshiaki Okada, Shohei Koyama, Ryo Suzuki, Taiki Aoshi

Journal of controlled release : official journal of the Controlled Release Society　Vol. 313　p. 106-119　2019年11月10日　研究論文（学術雑誌）

Single Cell Receptor Analysis Aided by a Centrifugal Microfluidic Device for Immune Cells Profiling

Chen Zhu, Wilfred Villariza Espulgar, Woosik Yoo, Shohei Koyama, Xiaoming Dou, Atsushi Kumanogoh, Eiichi Tamiya, Hyota Takamatsu, Masato Saito

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN　Vol. 92　No. 11　p. 1834-1839　2019年11月　研究論文（学術雑誌）

Monitoring antibody binding to T cells in a pembrolizumab-treated patient with lung adenocarcinoma on hemodialysis.

Osa A, Uenami T, Naito Y, Hirata H, Koyama S, Takimoto T, Shiroyama T, Futami S, Nakatsubo S, Sawa N, Yano Y, Nagatomo I, Takeda Y, Mori M, Kida H, Kumanogoh A

Thoracic cancer　Vol. 10　No. 11　p. 2183-2187　2019年11月

The therapeutic efficacy of intravenous immunoglobulin in anti-neutrophilic cytoplasmic antibody-associated vasculitis: a meta-analysis.

Shimizu T, Morita T, Kumanogoh A

Rheumatology (Oxford, England)　Vol. 59　No. 5　p. 959-967　2019年8月4日　研究論文（学術雑誌）

Immune adjuvant therapy using Bacillus Calmette-Guérin cell wall skeleton (BCG-CWS) in advanced malignancies: A phase 1 study of safety and immunogenicity assessments.

Nishida S, Tsuboi A, Tanemura A, Ito T, Nakajima H, Shirakata T, Morimoto S, Fujiki F, Hosen N, Oji Y, Kumanogoh A, Kawase I, Oka Y, Azuma I, Morita S, Sugiyama H

Medicine　Vol. 98　No. 33　2019年8月　研究論文（学術雑誌）

A lung abscess caused by secondary syphilis - the utility of polymerase chain reaction techniques in transbronchial biopsy: a case report.

Shinji Futami, Takayuki Takimoto, Futoshi Nakagami, Shingo Satoh, Masanari Hamaguchi, Muneyoshi Kuroyama, Kotaro Miyake, Shohei Koyama, Kota Iwahori, Haruhiko Hirata, Izumi Nagatomo, Yoshito Takeda, Hiroshi Kida, Atsushi Kumanogoh

BMC infectious diseases　Vol. 19　No. 1　p. 598-598　2019年7月9日　研究論文（学術雑誌）

The COMMD3/8 complex determines GRK6 specificity for chemoattractant receptors.

Akiko Nakai, Jun Fujimoto, Haruhiko Miyata, Ralf Stumm, Masashi Narazaki, Stefan Schulz, Yoshihiro Baba, Atsushi Kumanogoh, Kazuhiro Suzuki

The Journal of experimental medicine　Vol. 216　No. 7　p. 1630-1647　2019年7月1日

Response to: 'Blood plasma versus serum: which is right for sampling circulating membrane microvesicles in human subjects?' by Liu et al.

Yasuhiro Kato, JeongHoon Park, Hyota Takamatsu, Atsushi Kumanogoh

Annals of the rheumatic diseases　Vol. 79　No. 6　2019年5月16日　研究論文（学術雑誌）

Correction to: Drug tolerability and reasons for discontinuation of seven biologics in 4466 treatment courses of rheumatoid arthritis-the ANSWER cohort study.

Kosuke Ebina, Motomu Hashimoto, Wataru Yamamoto, Toru Hirano, Ryota Hara, Masaki Katayama, Akira Onishi, Koji Nagai, Yonsu Son, Hideki Amuro, Keiichi Yamamoto, Yuichi Maeda, Koichi Murata, Sadao Jinno, Tohru Takeuchi, Makoto Hirao, Atsushi Kumanogoh, Hideki Yoshikawa

Arthritis research & therapy　Vol. 21　No. 1　p. 114-114　2019年5月6日

Unique Case of Pseudoprogression Manifesting as Lung Cavitation After Pembrolizumab Treatment.

Kentaro Masuhiro, Takayuki Shiroyama, Izumi Nagatomo, Atsushi Kumanogoh

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer　Vol. 14　No. 5　2019年5月

Anti-receptor activator of nuclear factor κB ligand antibody treatment increases osteoclastogenesis-promoting IL-8 in patients with rheumatoid arthritis.

Takayoshi Morita, Yoshihito Shima, Kosuke Fujimoto, Hideki Tsuboi, Yukihiko Saeki, Masashi Narazaki, Atsushi Ogata, Atsushi Kumanogoh

International immunology　Vol. 31　No. 5　p. 277-285　2019年4月26日　研究論文（学術雑誌）

Transport of cellular misfolded proteins to the cell surface by HLA-B27 free heavy chain.

Hideki Yorifuji, Noriko Arase, Masako Kohyama, Toru Hirano, Tadahiro Suenaga, Atsushi Kumanogoh, Hisashi Arase

Biochemical and biophysical research communications　Vol. 511　No. 4　p. 862-868　2019年4月16日　研究論文（学術雑誌）

Drug tolerability and reasons for discontinuation of seven biologics in 4466 treatment courses of rheumatoid arthritis-the ANSWER cohort study.

Kosuke Ebina, Motomu Hashimoto, Wataru Yamamoto, Toru Hirano, Ryota Hara, Masaki Katayama, Akira Onishi, Koji Nagai, Yonsu Son, Hideki Amuro, Keiichi Yamamoto, Yuichi Maeda, Koichi Murata, Sadao Jinno, Tohru Takeuchi, Makoto Hirao, Atsushi Kumanogoh, Hideki Yoshikawa

Arthritis research & therapy　Vol. 21　No. 1　p. 91-91　2019年4月11日　研究論文（学術雑誌）

SEMA4A promotes eosinophil survival and contributes to eosinophil-mediated allergic diseases.

Yohei Maeda, Takeshi Tsuda, Yoshito Takeda, Shohei Koyama, Yoshitomo Hayama, Satoshi Nojima, Tetsuya Kimura, Daisuke Ito, Hyota Takamatsu, Sujin Kang, Masayuki Nishide, Keiko Morimoto, Takashi Hosokawa, Yuhei Kinehara, Yasuhiro Kato, Takeshi Nakatani, Kazuya Takeda, Masaki Hayama, Sho Obata, Hitoshi Akazawa, Takashi Shikina, Hidenori Inohara, Atsushi Kumanogoh

Allergology international : official journal of the Japanese Society of Allergology　Vol. 68　No. 2　p. 274-276　2019年4月

Long-term outcomes of advanced thymoma in patients undergoing preoperative chemotherapy or chemoradiotherapy followed by surgery: a 20-year experience.

Ryu Kanzaki, Takashi Kanou, Naoko Ose, Soichiro Funaki, Yasushi Shintani, Masato Minami, Hiroshi Kida, Kazuhiko Ogawa, Atsushi Kumanogoh, Meinoshin Okumura

Interactive cardiovascular and thoracic surgery　Vol. 28　No. 3　p. 360-367　2019年3月1日　研究論文（学術雑誌）

Peripheral T cell cytotoxicity predicts T cell function in the tumor microenvironment.

Kota Iwahori, Yasushi Shintani, Soichiro Funaki, Yoko Yamamoto, Mitsunobu Matsumoto, Tetsuya Yoshida, Akiko Morimoto-Okazawa, Atsunari Kawashima, Eiichi Sato, Stephen Gottschalk, Meinoshin Okumura, Atsushi Kumanogoh, Hisashi Wada

Scientific reports　Vol. 9　No. 1　p. 2636-2636　2019年2月22日　研究論文（学術雑誌）

Impact of sarcopenia in patients with advanced non-small cell lung cancer treated with PD-1 inhibitors: A preliminary retrospective study.

Takayuki Shiroyama, Izumi Nagatomo, Shohei Koyama, Haruhiko Hirata, Sumiyuki Nishida, Kotaro Miyake, Kiyoharu Fukushima, Yuya Shirai, Yuichi Mitsui, So Takata, Kentaro Masuhiro, Moto Yaga, Kota Iwahori, Yoshito Takeda, Hiroshi Kida, Atsushi Kumanogoh

Scientific reports　Vol. 9　No. 1　p. 2447-2447　2019年2月21日　研究論文（学術雑誌）

Ficolin-1 is a promising therapeutic target for autoimmune diseases.

Katayama M, Ota K, Nagi-Miura N, Ohno N, Yabuta N, Nojima H, Kumanogoh A, Hirano T

International immunology　Vol. 31　No. 1　p. 23-32　2019年2月6日

Eosinophil-derived neurotoxin enhances airway remodeling in eosinophilic chronic rhinosinusitis and correlates with disease severity.

Takeshi Tsuda, Yohei Maeda, Masayuki Nishide, Shohei Koyama, Yoshitomo Hayama, Satoshi Nojima, Hyota Takamatsu, Daisuke Okuzaki, Yuhei Kinehara, Yasuhiro Kato, Takeshi Nakatani, Sho Obata, Hitoshi Akazawa, Takashi Shikina, Kazuya Takeda, Masaki Hayama, Hidenori Inohara, Atsushi Kumanogoh

International immunology　Vol. 31　No. 1　p. 33-40　2019年2月6日　研究論文（学術雑誌）

Phenotypic Analysis of Tumor Tissue-Infiltrating Lymphocytes in Tumor Microenvironment of Bladder Cancer and Upper Urinary Tract Carcinoma.

Iwahori K, Shintani Y, Funaki S, Yamamoto Y, Matsumoto M, Yoshida T, Morimoto-Okazawa A, Kawashima A, Sato E, Gottschalk S, Okumura M, Kumanogoh A, Wada H

Sci Rep.　Vol. 9　No. 1　p. 2636-2636　2019年2月　研究論文（学術雑誌）

Towards centrifugation-assisted cell trapping and isolation in a two-phase liquid

Wilfred Espulgar, Yuga Okui, Masato Saito, Shohei Koyama, Atsushi Kumanogoh, Hyota Takamatsu, Eiichi Tamiya

23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019　p. 276-277　2019年　研究論文（国際会議プロシーディングス）

Single cell fluorometric granzyme B profiling of immunological cells as early immunotherapy response predictor

Jonathan Briones, Wilfred Espulgar, Hiroyuki Yoshikawa, Masato Saito, Shohei Koyama, Atsushi Kumanogoh, Hyouta Takamatsu, Eiichi Tamiya

23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019　p. 472-473　2019年　研究論文（国際会議プロシーディングス）

Clinical Course of Amyloid A Amyloidosis Secondary to Rheumatoid Arthritis Treated with Anti-Rheumatic Drugs Including Biologic Agent: Case Series in Answer Cohort

Hirano T, Maeda Y, Ebina K, Nagai K, Son Y, Amuro H, Hara R, Hashimoto M, Kumanogoh A

Arch Clin Med Case Rep　Vol. 3　No. 6　p. 508-517　2019年　研究論文（学術雑誌）

Drug tolerability and reasons for discontinuation of seven biologics in elderly patients with rheumatoid arthritis -The ANSWER cohort study.

Kosuke Ebina, Motomu Hashimoto, Wataru Yamamoto, Toru Hirano, Ryota Hara, Masaki Katayama, Akira Onishi, Koji Nagai, Yonsu Son, Hideki Amuro, Keiichi Yamamoto, Yuichi Maeda, Koichi Murata, Sadao Jinno, Tohru Takeuchi, Makoto Hirao, Atsushi Kumanogoh, Hideki Yoshikawa

PloS one　Vol. 14　No. 5　2019年　研究論文（学術雑誌）

PlexinA1 is crucial for the midline crossing of callosal axons during corpus callosum development in BALB/cAJ mice.

Hossain MM, Tsuzuki T, Sakakibara K, Imaizumi F, Ikegaya A, Inagaki M, Takahashi I, Ito T, Takamatsu H, Kumanogoh A, Negishi T, Yukawa K

PloS one　Vol. 14　No. 8　2019年　研究論文（学術雑誌）

The Outcomes of Induction Chemoradiotherapy Followed by Surgery for Clinical T3-4 Non-Small Cell Lung Cancer.

Ryu Kanzaki, Naoko Ose, Soichiro Funaki, Yasushi Shintani, Masato Minami, Osamu Suzuki, Hiroshi Kida, Kazuhiko Ogawa, Atsushi Kumanogoh, Meinoshin Okumura

Technology in cancer research & treatment　Vol. 18　p. 1533033819871327-1533033819871327　2019年1月1日　研究論文（学術雑誌）

Development and validation of a deep-learning model for scoring of radiographic finger joint destruction in rheumatoid arthritis.

Hirano T, Nishide M, Nonaka N, Seita J, Ebina K, Sakurada K, Kumanogoh A

Rheumatology advances in practice　Vol. 3　No. 2　2019年　研究論文（学術雑誌）

Eukaryotic translation initiation factor 3 subunit C is associated with acquired resistance to erlotinib in non-small cell lung cancer.

Takuya Shintani, Kazuma Higashisaka, Makiko Maeda, Masaya Hamada, Ryosuke Tsuji, Koudai Kurihara, Yuri Kashiwagi, Atsuhiro Sato, Masanori Obana, Ayaha Yamamoto, Keisuke Kawasaki, Ying Lin, Takashi Kijima, Yuhei Kinehara, Yoshihiro Miwa, Shinichiro Maeda, Eiichi Morii, Atsushi Kumanogoh, Yasuo Tsutsumi, Izumi Nagatomo, Yasushi Fujio

Oncotarget　Vol. 9　No. 101　p. 37520-37533　2018年12月25日　研究論文（学術雑誌）

Semaphorin 7A promotes EGFR-TKI resistance in EGFR mutant lung adenocarcinoma cells.

Yuhei Kinehara, Izumi Nagatomo, Shohei Koyama, Daisuke Ito, Satoshi Nojima, Ryota Kurebayashi, Yoshimitsu Nakanishi, Yasuhiko Suga, Yu Nishijima-Futami, Akio Osa, Takeshi Nakatani, Yasuhiro Kato, Masayuki Nishide, Yoshitomo Hayama, Masayoshi Higashiguchi, Osamu Morimura, Kotaro Miyake, Sujin Kang, Toshiyuki Minami, Haruhiko Hirata, Kota Iwahori, Takayuki Takimoto, Hyota Takamatsu, Yoshito Takeda, Naoki Hosen, Shigenori Hoshino, Yasushi Shintani, Meinoshin Okumura, Toru Kumagai, Kazumi Nishino, Fumio Imamura, Shin-Ichi Nakatsuka, Takashi Kijima, Hiroshi Kida, Atsushi Kumanogoh

JCI insight　Vol. 3　No. 24　2018年12月20日　研究論文（学術雑誌）

Integration of genetics and miRNA-target gene network identified disease biology implicated in tissue specificity.

Saori Sakaue, Jun Hirata, Yuichi Maeda, Eiryo Kawakami, Takuro Nii, Toshihiro Kishikawa, Kazuyoshi Ishigaki, Chikashi Terao, Ken Suzuki, Masato Akiyama, Naomasa Suita, Tatsuo Masuda, Kotaro Ogawa, Kenichi Yamamoto, Yukihiko Saeki, Masato Matsushita, Maiko Yoshimura, Hidetoshi Matsuoka, Katsunori Ikari, Atsuo Taniguchi, Hisashi Yamanaka, Hideya Kawaji, Timo Lassmann, Masayoshi Itoh, Hiroyuki Yoshitomi, Hiromu Ito, Koichiro Ohmura, Alistair R R Forrest, Yoshihide Hayashizaki, Piero Carninci, Atsushi Kumanogoh, Yoichiro Kamatani, Michiel de Hoon, Kazuhiko Yamamoto, Yukinori Okada

Nucleic acids research　Vol. 46　No. 22　p. 11898-11909　2018年12月14日　研究論文（学術雑誌）

Extremely strong infiltration of WT1-specific CTLs into mouse tumor by the combination vaccine with WT1-specific CTL and helper peptides.

Jun Nakata, Hiroko Nakajima, Hiromu Hayashibara, Kanako Imafuku, Soyoko Morimoto, Fumihiro Fujiki, Daisuke Motooka, Daisuke Okuzaki, Kana Hasegawa, Naoki Hosen, Akihiro Tsuboi, Yoshihiro Oka, Atsushi Kumanogoh, Yusuke Oji, Haruo Sugiyama

Oncotarget　Vol. 9　No. 89　p. 36029-36038　2018年11月13日　研究論文（学術雑誌）

Clinical implications of monitoring nivolumab immunokinetics in non-small cell lung cancer patients.

Akio Osa, Takeshi Uenami, Shohei Koyama, Kosuke Fujimoto, Daisuke Okuzaki, Takayuki Takimoto, Haruhiko Hirata, Yukihiro Yano, Soichiro Yokota, Yuhei Kinehara, Yujiro Naito, Tomoyuki Otsuka, Masaki Kanazu, Muneyoshi Kuroyama, Masanari Hamaguchi, Taro Koba, Yu Futami, Mikako Ishijima, Yasuhiko Suga, Yuki Akazawa, Hirotomo Machiyama, Kota Iwahori, Hyota Takamatsu, Izumi Nagatomo, Yoshito Takeda, Hiroshi Kida, Esra A Akbay, Peter S Hammerman, Kwok-Kin Wong, Glenn Dranoff, Masahide Mori, Takashi Kijima, Atsushi Kumanogoh

JCI insight　Vol. 3　No. 19　2018年10月4日　研究論文（学術雑誌）

Electrochemiluminescence-based Monitoring of Activated Human Neutrophils Using Luminol Derivative Immobilized onto Screen-printed Electrodes

Joyotu Mazumder, Yuka Kizawa, Wilfred Espulgar, Hiroyuki Yoshikawa, Masato Saito, Shouhei Koyama, Hyota Takamatsu, Atsushi Kumanogoh, Eiichi Tamiya

CHEMISTRY LETTERS　Vol. 47　No. 10　p. 1337-1340　2018年10月　研究論文（学術雑誌）

The Direct Oblique Method: A New Gold Standard for Bronchoscopic Navigation That is Superior to Automatic Methods.

Miyake K, Morimura O, Inoue T, Yoshida K, Nagatomo I, Kijima T, Kumanogoh A

Journal of bronchology & interventional pulmonology　Vol. 25　No. 4　p. 305-314　2018年10月　研究論文（学術雑誌）

Apoptosis-derived membrane vesicles drive the cGAS-STING pathway and enhance type I IFN production in systemic lupus erythematosus.

Kato Y, Park J, Takamatsu H, Konaka H, Aoki W, Aburaya S, Ueda M, Nishide M, Koyama S, Hayama Y, Kinehara Y, Hirano T, Shima Y, Narazaki M, Kumanogoh A

Annals of the rheumatic diseases　Vol. 77　No. 10　p. 1507-1515　2018年10月　研究論文（学術雑誌）

Minimal neonatal transfer of certolizumab pegol in a Japanese patient with rheumatoid arthritis.

Morita T, Fujimoto K, Shima Y, Ogata A, Kumanogoh A

Annals of the rheumatic diseases　Vol. 77　No. 9　2018年9月

Selecting suitable chemotherapies for PD-1/PD-L1 blockade to optimize the tumor immune microenvironment.

Koyama S, Nagatomo I, Kijima T, Kumanogoh A

Oncotarget　Vol. 9　No. 66　p. 32552-32553　2018年8月24日

In vivo visualisation of different modes of action of biological DMARDs inhibiting osteoclastic bone resorption.

Yoshinobu Matsuura, Junichi Kikuta, Yuika Kishi, Tetsuo Hasegawa, Daisuke Okuzaki, Toru Hirano, Masafumi Minoshima, Kazuya Kikuchi, Atsushi Kumanogoh, Masaru Ishii

Annals of the rheumatic diseases　Vol. 77　No. 8　p. 1219-1225　2018年8月　研究論文（学術雑誌）

Wilms tumour 1 peptide vaccine as a cure-oriented post-chemotherapy strategy for patients with acute myeloid leukaemia at high risk of relapse.

Jun Nakata, Yoshiki Nakae, Manabu Kawakami, Soyoko Morimoto, Daisuke Motooka, Naoki Hosen, Fumihiro Fujiki, Hiroko Nakajima, Kana Hasegawa, Sumiyuki Nishida, Akihiro Tsuboi, Yusuke Oji, Yoshihiro Oka, Atsushi Kumanogoh, Haruo Sugiyama

British journal of haematology　Vol. 182　No. 2　p. 287-290　2018年7月

WT1 peptide-based immunotherapy for advanced thymic epithelial malignancies.

Yusuke Oji, Masayoshi Inoue, Yoshito Takeda, Naoki Hosen, Yasushi Shintani, Manabu Kawakami, Takuya Harada, Yui Murakami, Miki Iwai, Mari Fukuda, Sumiyuki Nishida, Jun Nakata, Yoshiki Nakae, Satoshi Takashima, Toshiaki Shirakata, Hiroko Nakajima, Kana Hasegawa, Hiroshi Kida, Takashi Kijima, Soyoko Morimoto, Fumihiro Fujiki, Akihiro Tsuboi, Eiichi Morii, Satoshi Morita, Junichi Sakamoto, Atsushi Kumanogoh, Yoshihiro Oka, Meinoshin Okumura, Haruo Sugiyama

International journal of cancer　Vol. 142　No. 11　p. 2375-2382　2018年6月1日　研究論文（学術雑誌）

Lysosomal Protein Lamtor1 Controls Innate Immune Responses via Nuclear Translocation of Transcription Factor EB.

Yoshitomo Hayama, Tetsuya Kimura, Yoshito Takeda, Shigeyuki Nada, Shohei Koyama, Hyota Takamatsu, Sujin Kang, Daisuke Ito, Yohei Maeda, Masayuki Nishide, Satoshi Nojima, Hana Sarashina-Kida, Takashi Hosokawa, Yuhei Kinehara, Yasuhiro Kato, Takeshi Nakatani, Yoshimitsu Nakanishi, Takeshi Tsuda, Taro Koba, Masato Okada, Atsushi Kumanogoh

Journal of immunology (Baltimore, Md. : 1950)　Vol. 200　No. 11　p. 3790-3800　2018年6月1日　研究論文（学術雑誌）

Semaphorin 6D reverse signaling controls macrophage lipid metabolism and anti-inflammatory polarization.

Sujin Kang, Yoshimitsu Nakanishi, Yoshiyuki Kioi, Daisuke Okuzaki, Tetsuya Kimura, Hyota Takamatsu, Shohei Koyama, Satoshi Nojima, Masayuki Nishide, Yoshitomo Hayama, Yuhei Kinehara, Yasuhiro Kato, Takeshi Nakatani, Tomomi Shimogori, Junichi Takagi, Toshihiko Toyofuku, Atsushi Kumanogoh

Nature immunology　Vol. 19　No. 6　p. 561-570　2018年6月　研究論文（学術雑誌）

Cerebrospinal fluid mitochondrial DNA in neuromyelitis optica spectrum disorder.

Kazuya Yamashita, Makoto Kinoshita, Katsuichi Miyamoto, Akiko Namba, Mikito Shimizu, Toru Koda, Tomoyuki Sugimoto, Yuki Mori, Yoshichika Yoshioka, Yuji Nakatsuji, Atsushi Kumanogoh, Susumu Kusunoki, Hideki Mochizuki, Tatsusada Okuno

Journal of neuroinflammation　Vol. 15　No. 1　p. 125-125　2018年4月27日　研究論文（学術雑誌）

Double deletion of tetraspanins CD9 and CD81 in mice leads to a syndrome resembling accelerated aging.

Jin Y, Takeda Y, Kondo Y, Tripathi LP, Kang S, Takeshita H, Kuhara H, Maeda Y, Higashiguchi M, Miyake K, Morimura O, Koba T, Hayama Y, Koyama S, Nakanishi K, Iwasaki T, Tetsumoto S, Tsujino K, Kuroyama M, Iwahori K, Hirata H, Takimoto T, Suzuki M, Nagatomo I, Sugimoto K, Fujii Y, Kida H, Mizuguchi K, Ito M, Kijima T, Rakugi H, Mekada E, Tachibana I, Kumanogoh A

Scientific reports　Vol. 8　No. 1　p. 5145-5145　2018年3月23日　研究論文（学術雑誌）

Tracheobronchopathia Osteochondroplastica: A Cause of Difficult Tracheal Intubation.

Matsuki T, Takeda Y, Kida H, Kumanogoh A

Internal medicine (Tokyo, Japan)　Vol. 57　No. 6　p. 909-910　2018年3月15日

Combination Gemcitabine and WT1 Peptide Vaccination Improves Progression-Free Survival in Advanced Pancreatic Ductal Adenocarcinoma: A Phase II Randomized Study.

Sumiyuki Nishida, Takeshi Ishikawa, Shinichi Egawa, Shigeo Koido, Hiroaki Yanagimoto, Jun Ishii, Yoshihide Kanno, Satoshi Kokura, Hiroaki Yasuda, Mari Saito Oba, Maho Sato, Soyoko Morimoto, Fumihiro Fujiki, Hidetoshi Eguchi, Hiroaki Nagano, Atsushi Kumanogoh, Michiaki Unno, Masanori Kon, Hideaki Shimada, Kei Ito, Sadamu Homma, Yoshihiro Oka, Satoshi Morita, Haruo Sugiyama

Cancer immunology research　Vol. 6　No. 3　p. 320-331　2018年3月　研究論文（学術雑誌）

Clinical response to PD-1 blockade correlates with a sub-fraction of peripheral central memory CD4+ T cells in patients with malignant melanoma.

Takeuchi Y, Tanemura A, Tada Y, Katayama I, Kumanogoh A, Nishikawa H

International immunology　Vol. 30　No. 1　p. 13-22　2018年2月3日

High-efficient microfluidic chip for multiple receptor profile analysis of single immune cells through centrifugation

Chen Zhu, W. V. Espulgar, M. Saito, H. Takamatsu, H. Takamatsu, S. Koyama, A. Kumanogoh, E. Tamiya

22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018　Vol. 3　p. 1326-1329　2018年　研究論文（国際会議プロシーディングス）

Roles of Lamtor1 in Macrophages, CD4+ T-cells, and Regulatory T-cells.

Tetsuya Kimura, Atsushi Kumanogoh, Masato Okada

Critical reviews in immunology　Vol. 38　No. 5　p. 403-414　2018年　研究論文（学術雑誌）

Beneficial effects of fingolimod in MS patients with high serum Sema4A levels.

Toru Koda, Akiko Namba, Yuji Nakatsuji, Masaaki Niino, Yusei Miyazaki, Tomoyuki Sugimoto, Makoto Kinoshita, Kazushiro Takata, Kazuya Yamashita, Mikito Shimizu, Toshiyuki Fukazawa, Atsushi Kumanogoh, Hideki Mochizuki, Tatsusada Okuno

PloS one　Vol. 13　No. 3　2018年　研究論文（学術雑誌）

Drug retention and discontinuation reasons between seven biologics in patients with rheumatoid arthritis -The ANSWER cohort study.

Kosuke Ebina, Motomu Hashimoto, Wataru Yamamoto, Akira Ohnishi, Daijiro Kabata, Toru Hirano, Ryota Hara, Masaki Katayama, Shuzo Yoshida, Koji Nagai, Yonsu Son, Hideki Amuro, Kengo Akashi, Takanori Fujimura, Makoto Hirao, Keiichi Yamamoto, Ayumi Shintani, Atsushi Kumanogoh, Hideki Yoshikawa

PloS one　Vol. 13　No. 3　2018年　研究論文（学術雑誌）

The role of semaphorins in immune responses and autoimmune rheumatic diseases.

Nishide M, Kumanogoh A

Nature reviews. Rheumatology　Vol. 14　No. 1　p. 19-31　2018年1月　研究論文（学術雑誌）

Quantitative pulmonary blood flow measurement using 15O-H2O PET with and without tissue fraction correction: a comparison study.

Keiko Matsunaga, Masahiro Yanagawa, Tomoyuki Otsuka, Haruhiko Hirata, Takashi Kijima, Atsushi Kumanogoh, Noriyuki Tomiyama, Eku Shimosegawa, Jun Hatazawa

EJNMMI research　Vol. 7　No. 1　p. 102-102　2017年12月22日　研究論文（学術雑誌）

Screening of causative genes for fibrosis development in mice

Kiyoharu Fukushima, Takashi Satoh, Atsushi Kumanogoh, Shizuo Akira

2017年12月

The activated conformation of integrin β₇ is a novel multiple myeloma-specific target for CAR T cell therapy.

Hosen N, Matsunaga Y, Hasegawa K, Matsuno H, Nakamura Y, Makita M, Watanabe K, Yoshida M, Satoh K, Morimoto S, Fujiki F, Nakajima H, Nakata J, Nishida S, Tsuboi A, Oka Y, Manabe M, Ichihara H, Aoyama Y, Mugitani A, Nakao T, Hino M, Uchibori R, Ozawa K, Baba Y, Terakura S, Wada N, Morii E, Nishimura J, Takeda K, Oji Y, Sugiyama H, Takagi J, Kumanogoh A

Nature medicine　Vol. 23　No. 12　p. 1436-1443　2017年12月　研究論文（学術雑誌）

Gallbladder-derived surfactant protein D regulates gut commensal bacteria for maintaining intestinal homeostasis.

Sarashina-Kida H, Negishi H, Nishio J, Suda W, Nakajima Y, Yasui-Kato M, Iwaisako K, Kang S, Endo N, Yanai H, Asagiri M, Kida H, Hattori M, Kumanogoh A, Taniguchi T

Proceedings of the National Academy of Sciences of the United States of America　Vol. 114　No. 38　p. 10178-10183　2017年9月19日　研究論文（学術雑誌）

Lamtor1 Is Critically Required for CD4+ T Cell Proliferation and Regulatory T Cell Suppressive Function.

Takashi Hosokawa, Tetsuya Kimura, Shigeyuki Nada, Tatsusada Okuno, Daisuke Ito, Sujin Kang, Satoshi Nojima, Kazuya Yamashita, Takeshi Nakatani, Yoshitomo Hayama, Yasuhiro Kato, Yuhei Kinehara, Masayuki Nishide, Norihisa Mikami, Syohei Koyama, Hyota Takamatsu, Daisuke Okuzaki, Naganari Ohkura, Shimon Sakaguchi, Masato Okada, Atsushi Kumanogoh

Journal of immunology (Baltimore, Md. : 1950)　Vol. 199　No. 6　p. 2008-2019　2017年9月15日　研究論文（学術雑誌）

Carboplatin plus weekly nanoparticle albumin-bound paclitaxel in elderly patients with previously untreated advanced squamous non-small-cell lung cancer selected based on Mini Nutritional Assessment short-form scores: a multicenter phase 2 study.

Shiroyama T, Tamiya M, Minami S, Takata S, Masuhiro K, Futami-Nishijima Y, Uenami T, Mori M, Koba T, Matsuki T, Takimoto T, Suzuki H, Okamoto N, Komuta K, Hirashima T, Kumanogoh A, Kijima T

Cancer chemotherapy and pharmacology　Vol. 80　No. 3　p. 461-467　2017年9月　研究論文（学術雑誌）

CUBIC pathology: three-dimensional imaging for pathological diagnosis.

Satoshi Nojima, Etsuo A Susaki, Kyotaro Yoshida, Hiroyoshi Takemoto, Naoto Tsujimura, Shohei Iijima, Ko Takachi, Yujiro Nakahara, Shinichiro Tahara, Kenji Ohshima, Masako Kurashige, Yumiko Hori, Naoki Wada, Jun-Ichiro Ikeda, Atsushi Kumanogoh, Eiichi Morii, Hiroki R Ueda

Scientific reports　Vol. 7　No. 1　p. 9269-9269　2017年8月24日　研究論文（学術雑誌）

Interleukin-17A Promotes Lung Tumor Progression through Neutrophil Attraction to Tumor Sites and Mediating Resistance to PD-1 Blockade.

Akbay EA, Koyama S, Liu Y, Dries R, Bufe LE, Silkes M, Alam MM, Magee DM, Jones R, Jinushi M, Kulkarni M, Carretero J, Wang X, Warner-Hatten T, Cavanaugh JD, Osa A, Kumanogoh A, Freeman GJ, Awad MM, Christiani DC, Bueno R, Hammerman PS, Dranoff G, Wong KK

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer　Vol. 12　No. 8　p. 1268-1279　2017年8月

Semaphorin 4D inhibits neutrophil activation and is involved in the pathogenesis of neutrophil-mediated autoimmune vasculitis.

Masayuki Nishide, Satoshi Nojima, Daisuke Ito, Hyota Takamatsu, Shohei Koyama, Sujin Kang, Tetsuya Kimura, Keiko Morimoto, Takashi Hosokawa, Yoshitomo Hayama, Yuhei Kinehara, Yasuhiro Kato, Takeshi Nakatani, Yoshimitsu Nakanishi, Takeshi Tsuda, Jeong Hoon Park, Toru Hirano, Yoshihito Shima, Masashi Narazaki, Eiichi Morii, Atsushi Kumanogoh

Annals of the rheumatic diseases　Vol. 76　No. 8　p. 1440-1448　2017年8月　研究論文（学術雑誌）

Control of species-dependent cortico-motoneuronal connections underlying manual dexterity.

Gu Z, Kalambogias J, Yoshioka S, Han W, Li Z, Kawasawa YI, Pochareddy S, Li Z, Liu F, Xu X, Wijeratne HRS, Ueno M, Blatz E, Salomone J, Kumanogoh A, Rasin MR, Gebelein B, Weirauch MT, Sestan N, Martin JH, Yoshida Y

Science (New York, N.Y.)　Vol. 357　No. 6349　p. 400-404　2017年7月28日

Trastuzumab emtansine suppresses the growth of HER2-positive small-cell lung cancer in preclinical models.

Morimura O, Minami T, Kijima T, Koyama S, Otsuka T, Kinehara Y, Osa A, Higashiguchi M, Miyake K, Nagatomo I, Hirata H, Iwahori K, Takimoto T, Takeda Y, Kida H, Kumanogoh A

Biochemical and biophysical research communications　Vol. 488　No. 4　p. 596-602　2017年7月8日　研究論文（学術雑誌）

Clarifying the biological significance of the CHK2 K373E somatic mutation discovered in The Cancer Genome Atlas database

Higashiguchi Masayoshi, Nagatomo Izumi, Kijima Takashi, Morimura Osamu, Miyake Kotaro, Minami Toshiyuki, Koyama Shohei, Hirata Haruhiko, Iwahori Kota, Takimoto Takayuki, Takeda Yoshito, Kida Hiroshi, Kumanogoh Atsushi

CANCER RESEARCH　Vol. 77　2017年7月

Mouse model of Epstein-Barr virus LMP1- and LMP2A-driven germinal center B-cell lymphoproliferative disease.

Takeharu Minamitani, Yijie Ma, Hufeng Zhou, Hiroshi Kida, Chao-Yuan Tsai, Masanori Obana, Daisuke Okuzaki, Yasushi Fujio, Atsushi Kumanogoh, Bo Zhao, Hitoshi Kikutani, Elliott Kieff, Benjamin E Gewurz, Teruhito Yasui

Proceedings of the National Academy of Sciences of the United States of America　Vol. 114　No. 18　p. 4751-4756　2017年5月2日　研究論文（学術雑誌）

BATF2 inhibits immunopathological Th17 responses by suppressing Il23a expression during Trypanosoma cruzi infection.

Shoko Kitada, Hisako Kayama, Daisuke Okuzaki, Ritsuko Koga, Masao Kobayashi, Yasunobu Arima, Atsushi Kumanogoh, Masaaki Murakami, Masahito Ikawa, Kiyoshi Takeda

The Journal of experimental medicine　Vol. 214　No. 5　p. 1313-1331　2017年5月1日　研究論文（学術雑誌）

Regulation of intestinal homeostasis by the ulcerative colitis-associated gene RNF186.

Kosuke Fujimoto, Makoto Kinoshita, Hiroo Tanaka, Daisuke Okuzaki, Yosuke Shimada, Hisako Kayama, Ryu Okumura, Yoki Furuta, Masashi Narazaki, Atsushi Tamura, Shigetsugu Hatakeyama, Masahito Ikawa, Kiichiro Tsuchiya, Mamoru Watanabe, Atsushi Kumanogoh, Sachiko Tsukita, Kiyoshi Takeda

Mucosal Immunol　Vol. 10　No. 2　p. 446-459　2017年3月　研究論文（学術雑誌）

Regulation of intestinal homeostasis by the ulcerative colitis-associated gene RNF186.

Fujimoto K, Kinoshita M, Tanaka H, Okuzaki D, Shimada Y, Kayama H, Okumura R, Furuta Y, Narazaki M, Tamura A, Hatakeyama S, Ikawa M, Tsuchiya K, Watanabe M, Kumanogoh A, Tsukita S, Takeda K

Mucosal immunology　Vol. 10　No. 2　p. 446-459　2017年3月　研究論文（学術雑誌）

Erratum: Polarization of M2 macrophages requires Lamtor1 that integrates cytokine and amino-acid signals.

Kimura T, Nada S, Takegahara N, Okuno T, Nojima S, Kang S, Ito D, Morimoto K, Hosokawa T, Hayama Y, Mitsui Y, Sakurai N, Sarashina-Kida H, Nishide M, Maeda Y, Takamatsu H, Okuzaki D, Yamada M, Okada M, Kumanogoh A

Nature communications　Vol. 8　p. 14711-14711　2017年2月27日　研究論文（学術雑誌）

Classification of idiopathic interstitial pneumonias using anti-myxovirus resistance-protein 1 autoantibody.

Hamano Y, Kida H, Ihara S, Murakami A, Yanagawa M, Ueda K, Honda O, Tripathi LP, Arai T, Hirose M, Hamasaki T, Yano Y, Kimura T, Kato Y, Takamatsu H, Otsuka T, Minami T, Hirata H, Inoue K, Nagatomo I, Takeda Y, Mori M, Nishikawa H, Mizuguchi K, Kijima T, Kitaichi M, Tomiyama N, Inoue Y, Kumanogoh A

Scientific reports　Vol. 7　p. 43201-43201　2017年2月23日　研究論文（学術雑誌）

The roles of neuropilins in the immune system

Satoshi Nojima, Atsushi Kumanogoh

The Neuropilins: Role and Function in Health and Disease　p. 151-160　2017年2月6日　論文集(書籍)内論文

Rapid intracranial response to osimertinib, without radiotherapy, in nonsmall cell lung cancer patients harboring the EGFR T790M mutation: Two Case Reports.

Koba T, Kijima T, Takimoto T, Hirata H, Naito Y, Hamaguchi M, Otsuka T, Kuroyama M, Nagatomo I, Takeda Y, Kida H, Kumanogoh A

Medicine　Vol. 96　No. 6　2017年2月　研究論文（学術雑誌）

Identification of an atypical monocyte and committed progenitor involved in fibrosis.

Satoh T, Nakagawa K, Sugihara F, Kuwahara R, Ashihara M, Yamane F, Minowa Y, Fukushima K, Ebina I, Yoshioka Y, Kumanogoh A, Akira S

Nature　Vol. 541　No. 7635　p. 96-101　2017年1月5日　研究論文（学術雑誌）

Serum anti-citrullinated protein antibodies of a mother with rheumatoid arthritis pass through the placenta but do not cause arthritis in her neonate

T. Morita, Y. Shima, A. Kakigano, A. Ogata, A. Kumanogoh

SCANDINAVIAN JOURNAL OF RHEUMATOLOGY　Vol. 46　No. 1　p. 85-86　2017年

アレルギー学からみた内科疾患：病態解明から新規治療の開発へ、司会者のことば

楠 進, 熊ノ郷 淳

日本内科学会雑誌　Vol. 106　p. 1811-113,142　2017年　研究論文（学術雑誌）

Characterizing Semaphorin-Mediated Immune Responses Using an Antigen-Presentation Assay.

Satoshi Nojima, Atsushi Kumanogoh

Methods in molecular biology (Clifton, N.J.)　Vol. 1493　p. 379-391　2017年　研究論文（学術雑誌）

Fungal ITS1 Deep-Sequencing Strategies to Reconstruct the Composition of a 26-Species Community and Evaluation of the Gut Mycobiota of Healthy Japanese Individuals.

Motooka D, Fujimoto K, Tanaka R, Yaguchi T, Gotoh K, Maeda Y, Furuta Y, Kurakawa T, Goto N, Yasunaga T, Narazaki M, Kumanogoh A, Horii T, Iida T, Takeda K, Nakamura S

Frontiers in microbiology　Vol. 8　p. 238-238　2017年　研究論文（学術雑誌）

Wilms' Tumor Gene 1 (WT1) Peptide Vaccine Therapy for Hematological Malignancies: From CTL Epitope Identification to Recent Progress in Clinical Studies Including a Cure-Oriented Strategy.

Yoshihiro Oka, Akihiro Tsuboi, Jun Nakata, Sumiyuki Nishida, Naoki Hosen, Atsushi Kumanogoh, Yusuke Oji, Haruo Sugiyama

Oncology research and treatment　Vol. 40　No. 11　p. 682-690　2017年　研究論文（学術雑誌）

Febuxostat ameliorates secondary progressive experimental autoimmune encephalomyelitis by restoring mitochondrial energy production in a GOT2-dependent manner.

Josephe A Honorat, Yuji Nakatsuji, Mikito Shimizu, Makoto Kinoshita, Hisae Sumi-Akamaru, Tsutomu Sasaki, Kazushiro Takata, Toru Koda, Akiko Namba, Kazuya Yamashita, Eri Sanda, Manabu Sakaguchi, Atsushi Kumanogoh, Takashi Shirakura, Mizuho Tamura, Saburo Sakoda, Hideki Mochizuki, Tatsusada Okuno

PloS one　Vol. 12　No. 11　2017年　研究論文（学術雑誌）

Clarifying the biological significance of the CHK2 K373E somatic mutation discovered in The Cancer Genome Atlas database.

Higashiguchi M, Nagatomo I, Kijima T, Morimura O, Miyake K, Minami T, Koyama S, Hirata H, Iwahori K, Takimoto T, Takeda Y, Kida H, Kumanogoh A

FEBS letters　Vol. 590　No. 23　p. 4275-4286　2016年12月

Syndecan-4 as a biomarker to predict clinical outcome for glioblastoma multiforme treated with WT1 peptide vaccine.

Satoshi Takashima, Yoshihiro Oka, Fumihiro Fujiki, Soyoko Morimoto, Hiroko Nakajima, Yoshiki Nakae, Jun Nakata, Sumiyuki Nishida, Naoki Hosen, Naoya Tatsumi, Kenji Mizuguchi, Naoya Hashimoto, Yusuke Oji, Akihiro Tsuboi, Atsushi Kumanogoh, Haruo Sugiyama

Future science OA　Vol. 2　No. 4　2016年12月　研究論文（学術雑誌）

CAPS1 RNA Editing Promotes Dense Core Vesicle Exocytosis.

Miyake K, Ohta T, Nakayama H, Doe N, Terao Y, Oiki E, Nagatomo I, Yamashita Y, Abe T, Nishikura K, Kumanogoh A, Hashimoto K, Kawahara Y

Cell reports　Vol. 17　No. 8　p. 2004-2014　2016年11月15日　研究論文（学術雑誌）

The role of Sema4A in angiogenesis, immune responses, carcinogenesis, and retinal systems.

Ito D, Kumanogoh A

Cell adhesion & migration　Vol. 10　No. 6　p. 692-699　2016年11月

Dysbiosis Contributes to Arthritis Development via Activation of Autoreactive T Cells in the Intestine.

Maeda Y, Kurakawa T, Umemoto E, Motooka D, Ito Y, Gotoh K, Hirota K, Matsushita M, Furuta Y, Narazaki M, Sakaguchi N, Kayama H, Nakamura S, Iida T, Saeki Y, Kumanogoh A, Sakaguchi S, Takeda K

Arthritis & rheumatology (Hoboken, N.J.)　Vol. 68　No. 11　p. 2646-2661　2016年11月　研究論文（学術雑誌）

Polarization of M2 macrophages requires Lamtor1 that integrates cytokine and amino-acid signals.

Tetsuya Kimura, Shigeyuki Nada, Noriko Takegahara, Tatsusada Okuno, Satoshi Nojima, Sujin Kang, Daisuke Ito, Keiko Morimoto, Takashi Hosokawa, Yoshitomo Hayama, Yuichi Mitsui, Natsuki Sakurai, Hana Sarashina-Kida, Masayuki Nishide, Yohei Maeda, Hyota Takamatsu, Daisuke Okuzaki, Masaki Yamada, Masato Okada, Atsushi Kumanogoh

Nature communications　Vol. 7　p. 13130-13130　2016年10月12日　研究論文（学術雑誌）

[113th Scientific Meeting of the Japanese Society of Internal Medicine: Symposium: Insight into the Mechanism of Diseases on New Perspective Arising in Internal Medicine: From Epigenetics to Organ Associations: A New Perspective in the Regulation of Immun

Ito D, Kumanogoh A

Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine　Vol. 105　No. 9　p. 1732-8　2016年9月

LRRK1 is critical in the regulation of B-cell responses and CARMA1-dependent NF-κB activation.

Morimoto K, Baba Y, Shinohara H, Kang S, Nojima S, Kimura T, Ito D, Yoshida Y, Maeda Y, Sarashina-Kida H, Nishide M, Hosokawa T, Kato Y, Hayama Y, Kinehara Y, Okuno T, Takamatsu H, Hirano T, Shima Y, Narazaki M, Kurosaki T, Toyofuku T, Kumanogoh A

Scientific reports　Vol. 6　p. 25738-25738　2016年5月11日　研究論文（学術雑誌）

Sialylation converts arthritogenic IgG into inhibitors of collagen-induced arthritis.

Yuhsuke Ohmi, Wataru Ise, Akira Harazono, Daisuke Takakura, Hidehiro Fukuyama, Yoshihiro Baba, Masashi Narazaki, Hirofumi Shoda, Nobunori Takahashi, Yuki Ohkawa, Shuting Ji, Fumihiro Sugiyama, Keishi Fujio, Atsushi Kumanogoh, Kazuhiko Yamamoto, Nana Kawasaki, Tomohiro Kurosaki, Yoshimasa Takahashi, Koichi Furukawa

Nature communications　Vol. 7　p. 11205-11205　2016年4月5日　研究論文（学術雑誌）

LRRK1 plays an essential role in B-cell responses by regulating BCR-dependent NF-kappa B signaling

Morimoto K, Baba Y, Shinohara H, Kurosaki T, Toyofuku T, Kumanogoh A

European Journal of Immunology　Vol. 46　p. 847-848　2016年　研究論文（学術雑誌）

Glycosylation Status of CD43 Protein Is Associated with Resistance of Leukemia Cells to CTL-Mediated Cytolysis.

Kana Hasegawa, Satomi Tanaka, Fumihiro Fujiki, Soyoko Morimoto, Katsuhiko Nakano, Hiroko Kinoshita, Atsushi Okumura, Yuka Fujioka, Rika Urakawa, Hiroko Nakajima, Naoya Tatsumi, Jun Nakata, Satoshi Takashima, Sumiyuki Nishida, Akihiro Tsuboi, Yoshihiro Oka, Yusuke Oji, Eiji Miyoshi, Takako Hirata, Atsushi Kumanogoh, Haruo Sugiyama, Naoki Hosen

PloS one　Vol. 11　No. 3　p. e0152326-113　2016年

Altered composition of gut microbiota in rheumatoid arthritis patients.

Maeda Y, Kumanogoh A, Takeda K

Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology　Vol. 39　No. 1　p. 59-63　2016年　研究論文（学術雑誌）

Structure of the Plexin Ectodomain Bound by Semaphorin-Mimicking Antibodies.

Suzuki K, Tsunoda H, Omiya R, Matoba K, Baba T, Suzuki S, Segawa H, Kumanogoh A, Iwasaki K, Hattori K, Takagi J

PloS one　Vol. 11　No. 6　2016年

The Proportion of Regulatory T Cells in Patients with Rheumatoid Arthritis: A Meta-Analysis.

Morita T, Shima Y, Wing JB, Sakaguchi S, Ogata A, Kumanogoh A

PloS one　Vol. 11　No. 9　2016年　研究論文（学術雑誌）

[Semaphorins as treatment targets for cartilage and bone damage caused by rheumatoid arthritis].

Yoshida Y, Kumanogoh A

Clinical calcium　Vol. 25　No. 12　p. 1795-800　2015年12月

Optimization of Treatment Intervals of Tocilizumab and Golimumab By Measuring Serum Trough Levels in Rheumatoid Arthritis Patients

Yoshinobu Matsuura, Masashi Narazaki, Masayuki Nishide, Yasuhiro Kato, Hideki Yorifuji, Toru Hirano, Yoshihito Shima, Toshio Tanaka, Atsushi Ogata, Atsushi Kumanogoh

ARTHRITIS & RHEUMATOLOGY　Vol. 67　p. 815-816　2015年10月　研究論文（その他学術会議資料等）

Leucine-Rich Repeat Kinase 1 Regulates Autophagy through Turning On TBC1D2-Dependent Rab7 Inactivation.

Toyofuku T, Morimoto K, Sasawatari S, Kumanogoh A

Molecular and cellular biology　Vol. 35　No. 17　p. 3044-58　2015年9月1日　研究論文（学術雑誌）

mTOR Complex Signaling through the SEMA4A-Plexin B2 Axis Is Required for Optimal Activation and Differentiation of CD8+ T Cells.

Daisuke Ito, Satoshi Nojima, Masayuki Nishide, Tatsusada Okuno, Hyota Takamatsu, Sujin Kang, Tetsuya Kimura, Yuji Yoshida, Keiko Morimoto, Yohei Maeda, Takashi Hosokawa, Toshihiko Toyofuku, Jun Ohshima, Daisuke Kamimura, Masahiro Yamamoto, Masaaki Murakami, Eiichi Morii, Hiromi Rakugi, Yoshitaka Isaka, Atsushi Kumanogoh

Journal of immunology (Baltimore, Md. : 1950)　Vol. 195　No. 3　p. 934-43　2015年8月1日　研究論文（学術雑誌）

Two distinct effector memory cell populations of WT1 (Wilms' tumor gene 1)-specific cytotoxic T lymphocytes in acute myeloid leukemia patients.

Nakae Y, Oka Y, Fujiki F, Morimoto S, Kamiya T, Takashima S, Nakata J, Nishida S, Nakajima H, Hosen N, Tsuboi A, Kyo T, Oji Y, Mizuguchi K, Kumanogoh A, Sugiyama H

Cancer immunology, immunotherapy : CII　Vol. 64　No. 7　p. 791-804　2015年7月　研究論文（学術雑誌）

Semaphorin 4D Contributes to Rheumatoid Arthritis by Inducing Inflammatory Cytokine Production: Pathogenic and Therapeutic Implications.

Yuji Yoshida, Atsushi Ogata, Sujin Kang, Kousuke Ebina, Kenrin Shi, Satoshi Nojima, Tetsuya Kimura, Daisuke Ito, Keiko Morimoto, Masayuki Nishide, Takashi Hosokawa, Toru Hirano, Yoshihito Shima, Masashi Narazaki, Hideki Tsuboi, Yukihiko Saeki, Tetsuya Tomita, Toshio Tanaka, Atsushi Kumanogoh

Arthritis & rheumatology (Hoboken, N.J.)　Vol. 67　No. 6　p. 1481-90　2015年6月　研究論文（学術雑誌）

Interleukin-6/interleukin-21 signaling axis is critical in the pathogenesis of pulmonary arterial hypertension.

Hashimoto-Kataoka T, Hosen N, Sonobe T, Arita Y, Yasui T, Masaki T, Minami M, Inagaki T, Miyagawa S, Sawa Y, Murakami M, Kumanogoh A, Yamauchi-Takihara K, Okumura M, Kishimoto T, Komuro I, Shirai M, Sakata Y, Nakaoka Y

Proceedings of the National Academy of Sciences of the United States of America　Vol. 112　No. 20　p. E2677-86-86　2015年5月19日

Semaphorin-Plexin Signaling Controls Mitotic Spindle Orientation during Epithelial Morphogenesis and Repair.

Xia J, Swiercz JM, Bañón-Rodríguez I, Matković I, Federico G, Sun T, Franz T, Brakebusch CH, Kumanogoh A, Friedel RH, Martín-Belmonte F, Gröne HJ, Offermanns S, Worzfeld T

Developmental cell　Vol. 33　No. 3　p. 299-313　2015年5月4日

CD16+CD56+ cells are a potential culprit for hematuria in IgA nephropathy.

Hirotsugu Iwatani, Yasuyuki Nagasawa, Ryohei Yamamoto, Kenichiro Iio, Masayuki Mizui, Arata Horii, Tadashi Kitahara, Hidenori Inohara, Atsushi Kumanogoh, Enyu Imai, Hiromi Rakugi, Yoshitaka Isaka

Clinical and experimental nephrology　Vol. 19　No. 2　p. 216-24　2015年4月　研究論文（学術雑誌）

Favorable response to trastuzumab plus irinotecan combination therapy in two patients with HER2-positive relapsed small-cell lung cancer.

Kinehara Y, Minami T, Kijima T, Hoshino S, Morimura O, Otsuka T, Hayama Y, Fukushima K, Takeuchi Y, Higashiguchi M, Miyake K, Hirata H, Nagatomo I, Inoue K, Takeda Y, Kida H, Kumanogoh A

Lung cancer (Amsterdam, Netherlands)　Vol. 87　No. 3　p. 321-5　2015年3月　研究論文（学術雑誌）

CD72 negatively regulates mouse mast cell functions and down-regulates the expression of KIT and FcεRIα.

Kataoka TR, Kumanogoh A, Fukuishi N, Ueshima C, Hirata M, Moriyoshi K, Tsuruyama T, Haga H

International immunology　Vol. 27　No. 2　p. 95-103　2015年2月

Semaphorin 4D induces vaginal epithelial cell apoptosis to control mouse postnatal vaginal tissue remodeling.

Ito T, Bai T, Tanaka T, Yoshida K, Ueyama T, Miyajima M, Negishi T, Kawasaki T, Takamatsu H, Kikutani H, Kumanogoh A, Yukawa K

Molecular medicine reports　Vol. 11　No. 2　p. 829-36　2015年2月　研究論文（学術雑誌）

Semaphorins in the immune system

Satoshi Nojima, Atsushi Kumanogoh

Semaphorins: A Diversity of Emerging Physiological and Pathological Activities　p. 137-158　2015年1月1日　論文集(書籍)内論文

Expansion of range of joint motion following treatment of systemic sclerosis with tocilizumab.

Shima Y, Hosen N, Hirano T, Arimitsu J, Nishida S, Hagihara K, Narazaki M, Ogata A, Tanaka T, Kishimoto T, Kumanogoh A

Modern rheumatology　Vol. 25　No. 1　p. 134-7　2015年1月

Dapsone hypersensitivity syndrome-related lung injury without eosinophilia in the bronchoalveolar lavage fluid.

Kinehara Y, Kijima T, Inoue K, Hirata H, Takeuchi Y, Fukushima K, Hayama Y, Higashiguchi M, Morimura O, Miyake K, Minami T, Nagatomo I, Takeda Y, Kida H, Kumanogoh A

Internal medicine (Tokyo, Japan)　Vol. 54　No. 7　p. 827-31　2015年　研究論文（学術雑誌）

An Immunocompetent Mouse Model for MLL/AF9 Leukemia Reveals the Potential of Spontaneous Cytotoxic T-Cell Response to an Antigen Expressed in Leukemia Cells.

Kana Hasegawa, Satomi Tanaka, Fumihiro Fujiki, Soyoko Morimoto, Hiroko Nakajima, Naoya Tatsumi, Jun Nakata, Satoshi Takashima, Sumiyuki Nishida, Akihiro Tsuboi, Yoshihiro Oka, Yusuke Oji, Atsushi Kumanogoh, Haruo Sugiyama, Naoki Hosen

PloS one　Vol. 10　No. 12　2015年　研究論文（学術雑誌）

Comprehensive exploration of autoantibody in Behçet's disease: a novel autoantibody to claudin-1, an essential protein for tight junctions, is identified.

Morishima A, Hirano T, Nishikawa H, Nakai K, Sakaguchi S, Kumanogoh A

Joint, bone, spine : revue du rhumatisme　Vol. 81　No. 6　p. 546-8　2014年12月

Development of microscopic polyangiitis-related pulmonary fibrosis in a patient with autoimmune pulmonary alveolar proteinosis.

Kinehara Y, Kida H, Inoue Y, Hirose M, Nakabayashi A, Takeuchi Y, Hayama Y, Fukushima K, Hirata H, Inoue K, Minami T, Nagatomo I, Takeda Y, Funakoshi T, Kijima T, Kumanogoh A

BMC pulmonary medicine　Vol. 14　p. 172-172　2014年11月4日　研究論文（学術雑誌）

Germline variants in the SEMA4A gene predispose to familial colorectal cancer type X.

Eduard Schulz, Petra Klampfl, Stefanie Holzapfel, Andreas R Janecke, Peter Ulz, Wilfried Renner, Karl Kashofer, Satoshi Nojima, Anita Leitner, Armin Zebisch, Albert Wölfler, Sybille Hofer, Armin Gerger, Sigurd Lax, Christine Beham-Schmid, Verena Steinke, Ellen Heitzer, Jochen B Geigl, Christian Windpassinger, Gerald Hoefler, Michael R Speicher, C Richard Boland, Atsushi Kumanogoh, Heinz Sill

Nature communications　Vol. 5　p. 5191-5191　2014年10月13日　研究論文（学術雑誌）

A retrospective study of prognostic factors in patients with interstitial pneumonia receiving long-term oxygen therapy.

Higashiguchi M, Kijima T, Sumikawa H, Honda O, Minami T, Hirata H, Inoue K, Nagatomo I, Takeda Y, Kida H, Tomiyama N, Kumanogoh A

Lung　Vol. 192　No. 5　p. 729-37　2014年10月　研究論文（学術雑誌）

Vaccination strategies to improve outcome of hematopoietic stem cell transplant in leukemia patients: early evidence and future prospects.

Hosen N, Maeda T, Hashii Y, Tsuboi A, Nishida S, Nakata J, Nakae Y, Takashima S, Oji Y, Oka Y, Kumanogoh A, Sugiyama H

Expert review of hematology　Vol. 7　No. 5　p. 671-81　2014年10月　研究論文（学術雑誌）

In vivo eradication of MLL/ENL leukemia cells by NK cells in the absence of adaptive immunity

J. Nakata, K. Nakano, A. Okumura, Y. Mizutani, H. Kinoshita, M. Iwai, K. Hasegawa, S. Morimoto, F. Fujiki, N. Tatsumi, H. Nakajima, Y. Nakae, S. Nishida, A. Tsuboi, Y. Oji, Y. Oka, H. Sugiyama, A. Kumanogoh, N. Hosen

LEUKEMIA　Vol. 28　No. 6　p. 1316-1325　2014年6月　研究論文（学術雑誌）

Plexin-A1 is required for Toll-like receptor-mediated microglial activation in the development of lipopolysaccharide-induced encephalopathy.

Ito T, Yoshida K, Negishi T, Miyajima M, Takamatsu H, Kikutani H, Kumanogoh A, Yukawa K

International journal of molecular medicine　Vol. 33　No. 5　p. 1122-30　2014年5月　研究論文（学術雑誌）

Sema4A inhibits the therapeutic effect of IFN-β in EAE.

Koda T, Okuno T, Takata K, Honorat JA, Kinoshita M, Tada S, Moriya M, Sakoda S, Mochizuki H, Kumanogoh A, Nakatsuji Y

Journal of neuroimmunology　Vol. 268　No. 1-2　p. 43-9　2014年3月15日　研究論文（学術雑誌）

Wilms Tumor Gene ( WT1) Peptide- based Cancer Vaccine Combined With Gemcitabine for Patients With Advanced Pancreatic Cancer

Sumiyuki Nishida, Shigeo Koido, Yutaka Takeda, Sadamu Homma, Hideo Komita, Akitaka Takahara, Satoshi Morita, Toshinori Ito, Soyoko Morimoto, Kazuma Hara, Akihiro Tsuboi, Yoshihiro Oka, Satoru Yanagisawa, Yoichi Toyama, Masahiro Ikegami, Toru Kitagawa, Hidetoshi Eguchi, Hiroshi Wada, Hiroaki Nagano, Jun Nakata, Yoshiki Nakae, Naoki Hosen, Yusuke Oji, Toshio Tanaka, Ichiro Kawase, Atsushi Kumanogoh, Junichi Sakamoto, Yuichiro Doki, Masaki Mori, Toshifumi Ohkusa, Hisao Tajiri, Haruo Sugiyama

JOURNAL OF IMMUNOTHERAPY　Vol. 37　No. 2　p. 105-114　2014年2月　研究論文（学術雑誌）

Protection against colitis by CD100-dependent modulation of intraepithelial gamma delta T lymphocyte function

T. F. Meehan, D. A. Witherden, C-H Kim, K. Sendaydiego, I. Ye, O. Garijo, H. K. Komori, A. Kumanogoh, H. Kikutani, L. Eckmann, W. L. Havran

MUCOSAL IMMUNOLOGY　Vol. 7　No. 1　p. 134-142　2014年1月　研究論文（学術雑誌）

Community-acquired, hospital-acquired, and healthcare-associated pneumonia caused by Pseudomonas aeruginosa.

Fujii A, Seki M, Higashiguchi M, Tachibana I, Kumanogoh A, Tomono K

Respiratory medicine case reports　Vol. 12　p. 30-3　2014年　研究論文（学術雑誌）

Rapidly progressive pneumonia caused by Cryptococcus neoformans in the patient of granulomatosis with polyangiitis.

Nakabayashi A, Seki M, Hirano T, Hirata H, Tomono K, Kumanogoh A

Respiratory medicine case reports　Vol. 13　p. 13-5　2014年　研究論文（学術雑誌）

[The role of semaphorin family in immune systems].

Daisuke Ito, Satoshi Nojima, Atsushi Kumanogoh

Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology　Vol. 37　No. 1　p. 1-10　2014年　研究論文（学術雑誌）

Efficacy and safety of pirfenidone for idiopathic pulmonary fibrosis.

Takeda Y, Tsujino K, Kijima T, Kumanogoh A

Patient preference and adherence　Vol. 8　p. 361-70　2014年

Estrogen-dependent proteolytic cleavage of semaphorin 4D and plexin-B1 enhances semaphorin 4D-induced apoptosis during postnatal vaginal remodeling in pubescent mice.

Ito T, Bai T, Tanaka T, Yoshida K, Ueyama T, Miyajima M, Negishi T, Kawasaki T, Takamatsu H, Kikutani H, Kumanogoh A, Yukawa K

PloS one　Vol. 9　No. 5　2014年　研究論文（学術雑誌）

A retrospective analysis of 335 Japanese lung cancer patients who responded to initial gefitinib treatment

K. Nishino, F. Imamura, S. Morita, M. Mori, K. Komuta, T. Kijima, Y. Namba, T. Kumagai, S. Yamamoto, I. Tachibana, Y. Nakazawa, J. Uchida, S. Minami, R. Takahashi, Y. Yano, T. Okuyama, A. Kumanogoh

Lung Cancer　Vol. 82　No. 2　p. 299-304　2013年11月　研究論文（学術雑誌）

Molecular mechanism underlying the antiproliferative effect of suppressor of cytokine signaling-1 in non-small-cell lung cancer cells.

Shimada K, Serada S, Fujimoto M, Nomura S, Nakatsuka R, Harada E, Iwahori K, Tachibana I, Takahashi T, Kumanogoh A, Kishimoto T, Naka T

Cancer science　Vol. 104　No. 11　p. 1483-91　2013年11月　研究論文（学術雑誌）

Immunological functions of the neuropilins and plexins as receptors for semaphorins.

Kumanogoh A, Kikutani H

Nature reviews. Immunology　Vol. 13　No. 11　p. 802-14　2013年11月

CD72 regulates the growth of KIT-mutated leukemia cell line Kasumi-1.

Kataoka TR, Kumanogoh A, Hirata M, Moriyoshi K, Ueshima C, Kawahara M, Tsuruyama T, Haga H

Scientific reports　Vol. 3　p. 2861-2861　2013年10月4日

Validation of noninvasive morphological and diffusion imaging in mouse emphysema by micro-computed tomography and hyperpolarized (129)Xe magnetic resonance imaging.

Tetsumoto S, Takeda Y, Imai H, Kimura A, Jin Y, Nakanishi K, Maeda Y, Kuhara H, Tsujino K, Iwasaki T, Shigeta H, Kondo Y, Ito M, Minami T, Hirata H, Takahashi R, Kohmo S, Nagatomo I, Inoue K, Kida H, Kijima T, Tachibana I, Maeda N, Funahashi T, Shimomura I, Fujiwara H, Kumanogoh A

American journal of respiratory cell and molecular biology　Vol. 49　No. 4　p. 592-600　2013年10月　研究論文（学術雑誌）

Polymorphisms of CYP2D6 gene and gefitinib-induced hepatotoxicity.

Takimoto T, Kijima T, Otani Y, Nonen S, Namba Y, Mori M, Yokota S, Minami S, Komuta K, Uchida J, Imamura F, Furukawa M, Tsuruta N, Fujio Y, Azuma J, Tachibana I, Kumanogoh A

Clinical lung cancer　Vol. 14　No. 5　p. 502-7　2013年9月

Maintenance of complete remission after allogeneic stem cell transplantation in leukemia patients treated with Wilms tumor 1 peptide vaccine

T. Maeda, N. Hosen, K. Fukushima, A. Tsuboi, S. Morimoto, T. Matsui, H. Sata, J. Fujita, K. Hasegawa, S. Nishida, J. Nakata, Y. Nakae, S. Takashima, H. Nakajima, F. Fujiki, N. Tatsumi, T. Kondo, M. Hino, Y. Oji, Y. Oka, Y. Kanakura, A. Kumanogoh, H. Sugiyama

Blood Cancer Journal　Vol. 3　No. 8　2013年8月　研究論文（学術雑誌）

Favorable responses to tocilizumab in two patients with cancer-related cachexia.

Hirata H, Tetsumoto S, Kijima T, Kida H, Kumagai T, Takahashi R, Otani Y, Inoue K, Kuhara H, Shimada K, Nagatomo I, Takeda Y, Goya S, Yoshizaki K, Kawase I, Tachibana I, Kishimoto T, Kumanogoh A

Journal of pain and symptom management　Vol. 46　No. 2　p. e9-e13-e13　2013年8月

Echinoderm microtubule-associated protein-like 4 (EML4)-anaplastic lymphoma kinase (ALK) rearrangement in congenital pulmonary airway malformation.

Tetsumoto S, Kijima T, Morii E, Goya S, Minami T, Hirata H, Takahashi R, Kohmo S, Inoue K, Nagatomo I, Takeda Y, Kida H, Tachibana I, Kumanogoh A

Clinical lung cancer　Vol. 14　No. 4　p. 457-60　2013年7月　研究論文（学術雑誌）

Efficacy of Anti-IL-6 therapy for seronegative spondyloarthropathy

Atsushi Ogata, Toshio Tanaka, Atsushi Kumanogoh

Ankylosing Spondylitis: Symptoms, Treatment and Potential Complications　p. 37-52　2013年6月　論文集(書籍)内論文

IL-6 targeting strategy for various: Immune-mediated diseases other than rheumatoid arthritis: An update review

Toshio Tanaka, Atsushi Ogata, Yoshihito Shima, Masashi Narazaki, Atsushi Kumanogoh, Tadamitsu Kishimoto

Interleukin-6: Genetics, Clinical Applications and Role in Disease　p. 61-109　2013年4月　論文集(書籍)内論文

IL-6 targeting strategy for rheumatoid arthritis

Atsushi Ogata, Yuji Yoshida, Atsuyoshi Morishima, Atsushi Kumanogoh, Toshio Tanaka

Interleukin-6: Genetics, Clinical Applications and Role in Disease　p. 111-149　2013年4月　論文集(書籍)内論文

Functional human Th17 clones with WT1-specific helper activity.

Tachino S, Fujiki F, Oka Y, Tsuboi A, Morimoto S, Lin YH, Tamanaka T, Kondo K, Nakajima H, Nishida S, Hosen N, Oji Y, Kumanogoh A, Sugiyama H

Cancer immunology, immunotherapy : CII　Vol. 62　No. 4　p. 801-10　2013年4月　研究論文（学術雑誌）

HLA-DPB1*05: 01-restricted WT1332-specific TCR-transduced CD4+ T lymphocytes display a helper activity for WT1-specific CTL induction and a cytotoxicity against leukemia cells.

Lin Y, Fujiki F, Katsuhara A, Oka Y, Tsuboi A, Aoyama N, Tanii S, Nakajima H, Tatsumi N, Morimoto S, Tamanaka T, Tachino S, Hosen N, Nishida S, Oji Y, Kumanogoh A, Sugiyama H

Journal of immunotherapy (Hagerstown, Md. : 1997)　Vol. 36　No. 3　p. 159-70　2013年4月　研究論文（学術雑誌）

Semaphorins in bone development, homeostasis, and disease.

Kang S, Kumanogoh A

Seminars in cell & developmental biology　Vol. 24　No. 3　p. 163-71　2013年3月　研究論文（学術雑誌）

Dynamic visualization of RANKL and Th17-mediated osteoclast function.

Kikuta J, Wada Y, Kowada T, Wang Z, Sun-Wada GH, Nishiyama I, Mizukami S, Maiya N, Yasuda H, Kumanogoh A, Kikuchi K, Germain RN, Ishii M

The Journal of clinical investigation　Vol. 123　No. 2　p. 866-73　2013年2月　研究論文（学術雑誌）

[Immune semaphorins and allergic diseases].

Morihana T, Kumanogoh A

Arerugi = [Allergy]　Vol. 62　No. 2　p. 155-62　2013年2月

Deletion of tetraspanin CD9 diminishes lymphangiogenesis in vivo and in vitro.

Takeo Iwasaki, Yoshito Takeda, Kazuichi Maruyama, Yasuyuki Yokosaki, Kazuyuki Tsujino, Satoshi Tetsumoto, Hanako Kuhara, Kaori Nakanishi, Yasushi Otani, Yingji Jin, Satoshi Kohmo, Haruhiko Hirata, Ryo Takahashi, Mayumi Suzuki, Koji Inoue, Izumi Nagatomo, Sho Goya, Takashi Kijima, Toru Kumagai, Isao Tachibana, Ichiro Kawase, Atsushi Kumanogoh

The Journal of biological chemistry　Vol. 288　No. 4　p. 2118-31　2013年1月25日　研究論文（学術雑誌）

Retention of tocilizumab and anti-tumour necrosis factor drugs in the treatment of rheumatoid arthritis

Y. Hishitani, A. Ogata, Y. Shima, T. Hirano, K. Ebina, Y. Kunugiza, K. Shi, M. Narazaki, K. Hagihara, T. Tomita, H. Yoshikawa, T. Tanaka, A. Kumanogoh

SCANDINAVIAN JOURNAL OF RHEUMATOLOGY　Vol. 42　No. 4　p. 253-259　2013年　研究論文（学術雑誌）

An inhibitory role for Sema4A in antigen-specific allergic asthma.

Tetsuo Morihana, Sho Goya, Masayuki Mizui, Teruhito Yasui, Durubaka V R Prasad, Atsushi Kumanogoh, Manabu Tamura, Takashi Shikina, Yohei Maeda, Yoriko Iwamoto, Hidenori Inohara, Hitoshi Kikutani

Journal of clinical immunology　Vol. 33　No. 1　p. 200-9　2013年1月　研究論文（学術雑誌）

Involvement of STAT3 in immune evasion during lung tumorigenesis.

Kida H, Ihara S, Kumanogoh A

Oncoimmunology　Vol. 2　No. 1　2013年1月1日

Drug-induced thrombotic thrombocytopenic purpura successfully treated with recombinant human soluble thrombomodulin.

Nishijima Y, Hirata H, Himeno A, Kida H, Matsumoto M, Takahashi R, Otani Y, Inoue K, Nagatomo I, Takeda Y, Kijima T, Tachibana I, Fujimura Y, Kumanogoh A

Internal medicine (Tokyo, Japan)　Vol. 52　No. 10　p. 1111-4　2013年　研究論文（学術雑誌）

Calretinin mediates apoptosis in small cell lung cancer cells expressing tetraspanin CD9.

He P, Kuhara H, Tachibana I, Jin Y, Takeda Y, Tetsumoto S, Minami T, Kohmo S, Hirata H, Takahashi R, Inoue K, Nagatomo I, Kida H, Kijima T, Naka T, Morii E, Kawase I, Kumanogoh A

FEBS open bio　Vol. 3　p. 225-30　2013年　研究論文（学術雑誌）

Interleukin-16 promotes cardiac fibrosis and myocardial stiffening in heart failure with preserved ejection fraction.

Tamaki S, Mano T, Sakata Y, Ohtani T, Takeda Y, Kamimura D, Omori Y, Tsukamoto Y, Ikeya Y, Kawai M, Kumanogoh A, Hagihara K, Ishii R, Higashimori M, Kaneko M, Hasuwa H, Miwa T, Yamamoto K, Komuro I

PloS one　Vol. 8　No. 7　2013年　研究論文（学術雑誌）

Overcoming chemoresistance of small-cell lung cancer through stepwise HER2-targeted antibody-dependent cell-mediated cytotoxicity and VEGF-targeted antiangiogenesis.

Minami T, Kijima T, Kohmo S, Arase H, Otani Y, Nagatomo I, Takahashi R, Miyake K, Higashiguchi M, Morimura O, Ihara S, Tsujino K, Hirata H, Inoue K, Takeda Y, Kida H, Tachibana I, Kumanogoh A

Scientific reports　Vol. 3　p. 2669-2669　2013年　研究論文（学術雑誌）

Statins decrease lung inflammation in mice by upregulating tetraspanin CD9 in macrophages.

Jin Y, Tachibana I, Takeda Y, He P, Kang S, Suzuki M, Kuhara H, Tetsumoto S, Tsujino K, Minami T, Iwasaki T, Nakanishi K, Kohmo S, Hirata H, Takahashi R, Inoue K, Nagatomo I, Kida H, Kijima T, Ito M, Saya H, Kumanogoh A

PloS one　Vol. 8　No. 9　2013年　研究論文（学術雑誌）

DNA damage in rheumatoid arthritis: an age-dependent increase in the lipid peroxidation-derived DNA adduct, heptanone-etheno-2'-deoxycytidine.

Ogawa M, Matsuda T, Ogata A, Hamasaki T, Kumanogoh A, Toyofuku T, Tanaka T

Autoimmune diseases　Vol. 2013　p. 183487-183487　2013年　研究論文（学術雑誌）

Tocilizumab for the treatment of patients with refractory Takayasu arteritis.

Nakaoka Y, Higuchi K, Arita Y, Otsuki M, Yamamoto K, Hashimoto-Kataoka T, Yasui T, Ikeoka K, Ohtani T, Sakata Y, Shima Y, Kumanogoh A, Yamauchi-Takihara K, Tanaka T, Kishimoto T, Komuro I

International heart journal　Vol. 54　No. 6　p. 405-11　2013年

A point mutation in Semaphorin 4A associates with defective endosomal sorting and causes retinal degeneration.

Satoshi Nojima, Toshihiko Toyofuku, Hiroyuki Kamao, Chie Ishigami, Jun Kaneko, Tatsusada Okuno, Hyota Takamatsu, Daisuke Ito, Sujin Kang, Tetsuya Kimura, Yuji Yoshida, Keiko Morimoto, Yohei Maeda, Atsushi Ogata, Masahito Ikawa, Eiichi Morii, Katsuyuki Aozasa, Junichi Takagi, Masayo Takahashi, Atsushi Kumanogoh

Nature communications　Vol. 4　p. 1406-1406　2013年　研究論文（学術雑誌）

Phase II tailored S-1 regimen study of first-line chemotherapy in elderly patients with advanced and recurrent non-small cell lung cancer.

Shiroyama T, Kijima T, Komuta K, Yamamoto S, Minami S, Ogata Y, Okafuji K, Imamura F, Hirashima T, Tachibana I, Kawase I, Kumanogoh A

Cancer chemotherapy and pharmacology　Vol. 70　No. 6　p. 783-9　2012年12月

Recognition of a natural WT1 epitope by a modified WT1 peptide-specific T-cell receptor.

Tamanaka T, Oka Y, Fujiki F, Tsuboi A, Katsuhara A, Nakajima H, Hosen N, Nishida S, Lin YH, Tachino S, Akatsuka Y, Kuzushima K, Oji Y, Kumanogoh A, Sugiyama H

Anticancer research　Vol. 32　No. 12　p. 5201-9　2012年12月　研究論文（学術雑誌）

Suppression of metastases of small cell lung cancer cells in mice by a peptidic CXCR4 inhibitor TF14016.

Otani Y, Kijima T, Kohmo S, Oishi S, Minami T, Nagatomo I, Takahashi R, Hirata H, Suzuki M, Inoue K, Takeda Y, Kida H, Tachibana I, Fujii N, Kumanogoh A

FEBS letters　Vol. 586　No. 20　p. 3639-44　2012年10月19日　研究論文（学術雑誌）

CD138-negative clonogenic cells are plasma cells but not B cells in some multiple myeloma patients

N. Hosen, Y. Matsuoka, S. Kishida, J. Nakata, Y. Mizutani, K. Hasegawa, A. Mugitani, H. Ichihara, Y. Aoyama, S. Nishida, A. Tsuboi, F. Fujiki, N. Tatsumi, H. Nakajima, M. Hino, T. Kimura, K. Yata, M. Abe, Y. Oka, Y. Oji, A. Kumanogoh, H. Sugiyama

LEUKEMIA　Vol. 26　No. 9　p. 2135-2141　2012年9月　研究論文（学術雑誌）

[Regulation of immune responses by immune semaphorins].

Daisuke Ito, Satoshi Nojima, Atsushi Kumanogoh

Nihon rinsho. Japanese journal of clinical medicine　Vol. 70　No. 9　p. 1633-43　2012年9月　研究論文（学術雑誌）

The CD100 receptor interacts with its plexin B2 ligand to regulate epidermal γδ T cell function.

Witherden DA, Watanabe M, Garijo O, Rieder SE, Sarkisyan G, Cronin SJ, Verdino P, Wilson IA, Kumanogoh A, Kikutani H, Teyton L, Fischer WH, Havran WL

Immunity　Vol. 37　No. 2　p. 314-25　2012年8月24日

Dynamism of immune reactions and regulation.

Kurosaki T, Saito T, Kumanogoh A, Takeda K, Kaisho T

International immunology　Vol. 24　No. 8　p. 473-5　2012年8月

Tetraspanin CD151 protects against pulmonary fibrosis by maintaining epithelial integrity.

Tsujino K, Takeda Y, Arai T, Shintani Y, Inagaki R, Saiga H, Iwasaki T, Tetsumoto S, Jin Y, Ihara S, Minami T, Suzuki M, Nagatomo I, Inoue K, Kida H, Kijima T, Ito M, Kitaichi M, Inoue Y, Tachibana I, Takeda K, Okumura M, Hemler ME, Kumanogoh A

American journal of respiratory and critical care medicine　Vol. 186　No. 2　p. 170-80　2012年7月15日　研究論文（学術雑誌）

Inhibitory roles of signal transducer and activator of transcription 3 in antitumor immunity during carcinogen-induced lung tumorigenesis.

Ihara S, Kida H, Arase H, Tripathi LP, Chen YA, Kimura T, Yoshida M, Kashiwa Y, Hirata H, Fukamizu R, Inoue R, Hasegawa K, Goya S, Takahashi R, Minami T, Tsujino K, Suzuki M, Kohmo S, Inoue K, Nagatomo I, Takeda Y, Kijima T, Mizuguchi K, Tachibana I, Kumanogoh A

Cancer research　Vol. 72　No. 12　p. 2990-9　2012年6月15日　研究論文（学術雑誌）

Optic chiasm presentation of Semaphorin6D in the context of Plexin-A1 and Nr-CAM promotes retinal axon midline crossing.

Kuwajima T, Yoshida Y, Takegahara N, Petros TJ, Kumanogoh A, Jessell TM, Sakurai T, Mason C

Neuron　Vol. 74　No. 4　p. 676-90　2012年5月24日

Elevation of Sema4A implicates Th cell skewing and the efficacy of IFN-β therapy in multiple sclerosis.

Nakatsuji Y, Okuno T, Moriya M, Sugimoto T, Kinoshita M, Takamatsu H, Nojima S, Kimura T, Kang S, Ito D, Nakagawa Y, Toyofuku T, Takata K, Nakano M, Kubo M, Suzuki S, Matsui-Hasumi A, Uto-Konomi A, Ogata A, Mochizuki H, Sakoda S, Kumanogoh A

Journal of immunology (Baltimore, Md. : 1950)　Vol. 188　No. 10　p. 4858-65　2012年5月15日　研究論文（学術雑誌）

Osteoprotection by semaphorin 3A.

Hayashi M, Nakashima T, Taniguchi M, Kodama T, Kumanogoh A, Takayanagi H

Nature　Vol. 485　No. 7396　p. 69-74　2012年5月3日

Endosomal sorting by Semaphorin 4A in retinal pigment epithelium supports photoreceptor survival.

Toshihiko Toyofuku, Satoshi Nojima, Takako Ishikawa, Hyota Takamatsu, Tohru Tsujimura, Akiyoshi Uemura, Junko Matsuda, Takaharu Seki, Atsushi Kumanogoh

Genes & development　Vol. 26　No. 8　p. 816-29　2012年4月15日　研究論文（学術雑誌）

A case of Behçet's disease treated with a humanized anti-interleukin-6 receptor antibody, tocilizumab.

Hirano T, Ohguro N, Hohki S, Hagihara K, Shima Y, Narazaki M, Ogata A, Yoshizaki K, Kumanogoh A, Kishimoto T, Tanaka T

Modern rheumatology　Vol. 22　No. 2　p. 298-302　2012年4月

HER2 as therapeutic target for overcoming ATP-binding cassette transporter-mediated chemoresistance in small cell lung cancer.

Minami T, Kijima T, Otani Y, Kohmo S, Takahashi R, Nagatomo I, Hirata H, Suzuki M, Inoue K, Takeda Y, Kida H, Tachibana I, Kumanogoh A

Molecular cancer therapeutics　Vol. 11　No. 4　p. 830-41　2012年4月　研究論文（学術雑誌）

Biased usage of T cell receptor β-chain variable region genes of Wilms' tumor gene (WT1)-specific CD8+ T cells in patients with solid tumors and healthy donors.

Soyoko Morimoto, Yoshihiro Oka, Akihiro Tsuboi, Yukie Tanaka, Fumihiro Fujiki, Hiroko Nakajima, Naoki Hosen, Sumiyuki Nishida, Jun Nakata, Yoshiki Nakae, Motohiko Maruno, Akira Myoui, Takayuki Enomoto, Shuichi Izumoto, Mitsugu Sekimoto, Naoki Kagawa, Naoya Hashimoto, Toshiki Yoshimine, Yusuke Oji, Atsushi Kumanogoh, Haruo Sugiyama

Cancer Sci.　Vol. 103　No. 3　p. 408-414　2012年3月　研究論文（学術雑誌）

Biased usage of T cell receptor β-chain variable region genes of Wilms' tumor gene (WT1)-specific CD8+ T cells in patients with solid tumors and healthy donors.

Morimoto S, Oka Y, Tsuboi A, Tanaka Y, Fujiki F, Nakajima H, Hosen N, Nishida S, Nakata J, Nakae Y, Maruno M, Myoui A, Enomoto T, Izumoto S, Sekimoto M, Kagawa N, Hashimoto N, Yoshimine T, Oji Y, Kumanogoh A, Sugiyama H

Cancer science　Vol. 103　No. 3　p. 408-14　2012年3月　研究論文（学術雑誌）

Diverse roles for semaphorin-plexin signaling in the immune system.

Takamatsu H, Kumanogoh A

Trends in immunology　Vol. 33　No. 3　p. 127-35　2012年3月　研究論文（学術雑誌）

Intestinal epithelial cell-derived semaphorin 7A negatively regulates development of colitis via αvβ1 integrin.

Kang S, Okuno T, Takegahara N, Takamatsu H, Nojima S, Kimura T, Yoshida Y, Ito D, Ohmae S, You DJ, Toyofuku T, Jang MH, Kumanogoh A

Journal of immunology (Baltimore, Md. : 1950)　Vol. 188　No. 3　p. 1108-16　2012年2月1日　研究論文（学術雑誌）

Therapeutic implications of tocilizumab, a humanized anti-interleukin-6 receptor antibody, for various immune-mediated diseases: An update review

Toshio Tanaka, Atsushi Ogata, Yoshihito Shima, Masashi Narazaki, Atsushi Kumanogoh, Tadamitsu Kishimoto

Current Rheumatology Reviews　Vol. 8　No. 3　p. 209-226　2012年　研究論文（学術雑誌）

Psoriatic arthritis in two patients with an inadequate response to treatment with tocilizumab.

Ogata A, Umegaki N, Katayama I, Kumanogoh A, Tanaka T

Joint, bone, spine : revue du rhumatisme　Vol. 79　No. 1　p. 85-7　2012年1月

Early [18F]fluorodeoxyglucose positron emission tomography at two days of gefitinib treatment predicts clinical outcome in patients with adenocarcinoma of the lung.

Ryo Takahashi, Haruhiko Hirata, Isao Tachibana, Eku Shimosegawa, Atsuo Inoue, Izumi Nagatomo, Yoshito Takeda, Hiroshi Kida, Sho Goya, Takashi Kijima, Mitsuhiro Yoshida, Toru Kumagai, Atsushi Kumanogoh, Meinoshin Okumura, Jun Hatazawa, Ichiro Kawase

Clinical cancer research : an official journal of the American Association for Cancer Research　Vol. 18　No. 1　p. 220-8　2012年1月1日　研究論文（学術雑誌）

Adiponectin: a novel link between adipocytes and COPD.

Takeda Y, Nakanishi K, Tachibana I, Kumanogoh A

Vitamins and hormones　Vol. 90　p. 419-35　2012年　研究論文（学術雑誌）

Pathological role of interleukin-6 in psoriatic arthritis.

Ogata A, Kumanogoh A, Tanaka T

Arthritis　Vol. 2012　p. 713618-713618　2012年

Tocilizumab, a humanized anti-interleukin-6 receptor antibody, for the treatment of autoimmune disorders

Toshio Tanaka, Keisuke Hagihara, Yoshihito Shima, Masashi Narazaki, Atsushi Ogata, Atsushi Kumanogoh

DRUG DEVELOPMENT RESEARCH　Vol. 72　No. 8　p. 717-732　2011年12月　研究論文（学術雑誌）

The role of immune semaphorins in multiple sclerosis.

Tatsusada Okuno, Yuji Nakatsuji, Atsushi Kumanogoh

FEBS letters　Vol. 585　No. 23　p. 3829-35　2011年12月1日　研究論文（学術雑誌）

[Involvement of semaphorins in immune regulations].

Takamatsu H, Kumanogoh A

Seikagaku. The Journal of Japanese Biochemical Society　Vol. 83　No. 12　p. 1103-9　2011年12月　研究論文（学術雑誌）

The action of Semaphorin7A on thalamocortical axon branching.

Fukunishi A, Maruyama T, Zhao H, Tiwari M, Kang S, Kumanogoh A, Yamamoto N

Journal of neurochemistry　Vol. 118　No. 6　p. 1008-15　2011年9月　研究論文（学術雑誌）

Ectopic myelinating oligodendrocytes in the dorsal spinal cord as a consequence of altered semaphorin 6D signaling inhibit synapse formation.

Leslie JR, Imai F, Fukuhara K, Takegahara N, Rizvi TA, Friedel RH, Wang F, Kumanogoh A, Yoshida Y

Development (Cambridge, England)　Vol. 138　No. 18　p. 4085-95　2011年9月

[WT1 peptide-based immunotherapy for the treatment of malignancies: focusing on hematological neoplasms].

Oka Y, Tsuboi A, Nishida S, Hosen N, Nakata J, Hashii Y, Maeda T, Oji Y, Kumanogoh A, Sugiyama H

[Rinsho ketsueki] The Japanese journal of clinical hematology　Vol. 52　No. 5　p. 235-42　2011年5月　研究論文（学術雑誌）

A molecular mechanism that regulates medially oriented axonal growth of upper layer neurons in the developing neocortex.

Zhao H, Maruyama T, Hattori Y, Sugo N, Takamatsu H, Kumanogoh A, Shirasaki R, Yamamoto N

The Journal of comparative neurology　Vol. 519　No. 5　p. 834-48　2011年4月1日　研究論文（学術雑誌）

RGMa modulates T cell responses and is involved in autoimmune encephalomyelitis.

Muramatsu R, Kubo T, Mori M, Nakamura Y, Fujita Y, Akutsu T, Okuno T, Taniguchi J, Kumanogoh A, Yoshida M, Mochizuki H, Kuwabara S, Yamashita T

Nature medicine　Vol. 17　No. 4　p. 488-94　2011年4月　研究論文（学術雑誌）

Identification of semaphorin 4B as a negative regulator of basophil-mediated immune responses.

Yukinobu Nakagawa, Hyota Takamatsu, Tatsusada Okuno, Sujin Kang, Satoshi Nojima, Tetsuya Kimura, Tatsuki R Kataoka, Masahito Ikawa, Toshihiko Toyofuku, Ichiro Katayama, Atsushi Kumanogoh

Journal of immunology (Baltimore, Md. : 1950)　Vol. 186　No. 5　p. 2881-8　2011年3月1日　研究論文（学術雑誌）

Semaphorin 4C and 4G are ligands of Plexin-B2 required in cerebellar development.

Maier V, Jolicoeur C, Rayburn H, Takegahara N, Kumanogoh A, Kikutani H, Tessier-Lavigne M, Wurst W, Friedel RH

Molecular and cellular neurosciences　Vol. 46　No. 2　p. 419-31　2011年2月

Control of bone resorption by semaphorin 4D is dependent on ovarian function.

Dacquin R, Domenget C, Kumanogoh A, Kikutani H, Jurdic P, Machuca-Gayet I

PloS one　Vol. 6　No. 10　2011年

The lactic acid bacterium Pediococcus acidilactici suppresses autoimmune encephalomyelitis by inducing IL-10-producing regulatory T cells.

Kazushiro Takata, Makoto Kinoshita, Tatsusada Okuno, Masayuki Moriya, Tohru Kohda, Josephe A Honorat, Tomoyuki Sugimoto, Atsushi Kumanogoh, Hisako Kayama, Kiyoshi Takeda, Saburo Sakoda, Yuji Nakatsuji

PloS one　Vol. 6　No. 11　2011年　研究論文（学術雑誌）

Diminished contact-dependent reinforcement of Syk activation underlies impaired thrombus growth in mice lacking Semaphorin 4D.

Wannemacher KM, Zhu L, Jiang H, Fong KP, Stalker TJ, Lee D, Tran AN, Neeves KB, Maloney S, Kumanogoh A, Kikutani H, Hammer DA, Diamond SL, Brass LF

Blood　Vol. 116　No. 25　p. 5707-15　2010年12月16日

Integral roles of a guanine nucleotide exchange factor, FARP2, in osteoclast podosome rearrangements.

Noriko Takegahara, Sujin Kang, Satoshi Nojima, Hyota Takamatsu, Tatsusada Okuno, Hitoshi Kikutani, Toshihiko Toyofuku, Atsushi Kumanogoh

FASEB journal : official publication of the Federation of American Societies for Experimental Biology　Vol. 24　No. 12　p. 4782-92　2010年12月　研究論文（学術雑誌）

Th1 cells promote neurite outgrowth from cortical neurons via a mechanism dependent on semaphorins.

Ishii H, Kubo T, Kumanogoh A, Yamashita T

Biochemical and biophysical research communications　Vol. 402　No. 1　p. 168-72　2010年11月5日

Structural basis for semaphorin signalling through the plexin receptor.

Nogi T, Yasui N, Mihara E, Matsunaga Y, Noda M, Yamashita N, Toyofuku T, Uchiyama S, Goshima Y, Kumanogoh A, Takagi J

Nature　Vol. 467　No. 7319　p. 1123-7　2010年10月28日　研究論文（学術雑誌）

Roles of Sema4D and Plexin-B1 in tumor progression.

Ch'ng ES, Kumanogoh A

Molecular cancer　Vol. 9　p. 251-251　2010年9月21日

Deletion of Sema4D gene reduces intimal neovascularization and plaque growth in apolipoprotein E-deficient mice.

Yukawa K, Tanaka T, Kishino M, Yoshida K, Takeuchi N, Ito T, Takamatsu H, Kikutani H, Kumanogoh A

International journal of molecular medicine　Vol. 26　No. 1　p. 39-44　2010年7月　研究論文（学術雑誌）

Semaphorins guide the entry of dendritic cells into the lymphatics by activating myosin II.

Hyota Takamatsu, Noriko Takegahara, Yukinobu Nakagawa, Michio Tomura, Masahiko Taniguchi, Roland H Friedel, Helen Rayburn, Marc Tessier-Lavigne, Yutaka Yoshida, Tatsusada Okuno, Masayuki Mizui, Sujin Kang, Satoshi Nojima, Tohru Tsujimura, Yuji Nakatsuji, Ichiro Katayama, Toshihiko Toyofuku, Hitoshi Kikutani, Atsushi Kumanogoh

Nature immunology　Vol. 11　No. 7　p. 594-600　2010年7月　研究論文（学術雑誌）

The study of cytokines by Japanese researchers: a historical perspective.

Kumanogoh A, Ogata M

International immunology　Vol. 22　No. 5　p. 341-5　2010年5月

Anti-aquaporin-4 antibody induces astrocytic cytotoxicity in the absence of CNS antigen-specific T cells.

Makoto Kinoshita, Yuji Nakatsuji, Takashi Kimura, Masayuki Moriya, Kazushiro Takata, Tatsusada Okuno, Atsushi Kumanogoh, Koji Kajiyama, Hiroo Yoshikawa, Saburo Sakoda

Biochemical and biophysical research communications　Vol. 394　No. 1　p. 205-10　2010年3月26日　研究論文（学術雑誌）

CD72 negatively regulates KIT-mediated responses in human mast cells.

Kataoka TR, Kumanogoh A, Bandara G, Metcalfe DD, Gilfillan AM

Journal of immunology (Baltimore, Md. : 1950)　Vol. 184　No. 5　p. 2468-75　2010年3月1日

Regulation of immune cell responses by semaphorins and their receptors.

Takamatsu H, Okuno T, Kumanogoh A

Cellular & molecular immunology　Vol. 7　No. 2　p. 83-8　2010年3月　研究論文（学術雑誌）

A midline switch of receptor processing regulates commissural axon guidance in vertebrates.

Nawabi H, Briançon-Marjollet A, Clark C, Sanyas I, Takamatsu H, Okuno T, Kumanogoh A, Bozon M, Takeshima K, Yoshida Y, Moret F, Abouzid K, Castellani V

Genes & development　Vol. 24　No. 4　p. 396-410　2010年2月15日　研究論文（学術雑誌）

Sema4A induces cell morphological changes through B-type plexin-mediated signaling.

Yukawa K, Tanaka T, Yoshida K, Takeuchi N, Ito T, Takamatsu H, Kikutani H, Kumanogoh A

International journal of molecular medicine　Vol. 25　No. 2　p. 225-30　2010年2月　研究論文（学術雑誌）

Roles of Sema4D-plexin-B1 interactions in the central nervous system for pathogenesis of experimental autoimmune encephalomyelitis.

Tatsusada Okuno, Yuji Nakatsuji, Masayuki Moriya, Hyota Takamatsu, Satoshi Nojima, Noriko Takegahara, Toshihiko Toyofuku, Yukinobu Nakagawa, Sujin Kang, Roland H Friedel, Saburo Sakoda, Hitoshi Kikutani, Atsushi Kumanogoh

Journal of immunology (Baltimore, Md. : 1950)　Vol. 184　No. 3　p. 1499-506　2010年2月1日　研究論文（学術雑誌）

Semaphorins and their receptors: novel features of neural guidance molecules.

Kumanogoh A, Kikutani H

Proceedings of the Japan Academy. Series B, Physical and biological sciences　Vol. 86　No. 6　p. 611-20　2010年

Neuromyelitis optica: Passive transfer to rats by human immunoglobulin.

Makoto Kinoshita, Yuji Nakatsuji, Takashi Kimura, Masayuki Moriya, Kazushiro Takata, Tatsusada Okuno, Atsushi Kumanogoh, Koji Kajiyama, Hiroo Yoshikawa, Saburo Sakoda

Biochemical and biophysical research communications　Vol. 386　No. 4　p. 623-7　2009年9月4日　研究論文（学術雑誌）

Endogenous CD100 promotes glomerular injury and macrophage recruitment in experimental crescentic glomerulonephritis.

Li M, O'Sullivan KM, Jones LK, Lo C, Semple T, Kumanogoh A, Kikutani H, Holdsworth SR, Kitching R

Immunology　Vol. 128　No. 1　p. 114-22　2009年9月

Disruption of SEMA4D ameliorates platelet hypersensitivity in dyslipidemia and confers protection against the development of atherosclerosis.

Zhu L, Stalker TJ, Fong KP, Jiang H, Tran A, Crichton I, Lee EK, Neeves KB, Maloney SF, Kikutani H, Kumanogoh A, Pure E, Diamond SL, Brass LF

Arteriosclerosis, thrombosis, and vascular biology　Vol. 29　No. 7　p. 1039-45　2009年7月

[New paradigm on host defence mechanisms].

Kumanogoh A, Takeda K

Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme　Vol. 54　No. 8 Suppl　p. 1073-5　2009年6月

[Immune semaphorins: involvement of semaphorins in various phases of immune responses].

Takegahara N, Kumanogoh A

Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme　Vol. 54　No. 8 Suppl　p. 1101-7　2009年6月

Sema4D/CD100 deficiency leads to superior performance in mouse motor behavior.

Yukawa K, Tanaka T, Takeuchi N, Iso H, Li L, Kohsaka A, Waki H, Miyajima M, Maeda M, Kikutani H, Kumanogoh A

The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques　Vol. 36　No. 3　p. 349-55　2009年5月

Astrocytic necrosis is induced by anti-aquaporin-4 antibody-positive serum.

Makoto Kinoshita, Yuji Nakatsuji, Masayuki Moriya, Tatsusada Okuno, Atsushi Kumanogoh, Misa Nakano, Toshiyuki Takahashi, Kazuo Fujihara, Keiko Tanaka, Saburo Sakoda

Neuroreport　Vol. 20　No. 5　p. 508-12　2009年3月25日　研究論文（学術雑誌）

Signal adaptor DAP10 associates with MDL-1 and triggers osteoclastogenesis in cooperation with DAP12.

Inui M, Kikuchi Y, Aoki N, Endo S, Maeda T, Sugahara-Tobinai A, Fujimura S, Nakamura A, Kumanogoh A, Colonna M, Takai T

Proceedings of the National Academy of Sciences of the United States of America　Vol. 106　No. 12　p. 4816-21　2009年3月24日　研究論文（学術雑誌）

Sema4D/CD100 DEFICIENCY LEADS TO SUPERIOR PERFORMANCE IN MOUSE MOTOR BEHAVIOR

Kazunori Yukawa, Tetsuji Tanaka, Noriko Takeuchi, Hiroyuki Iso, Li Li, Akira Kohsaka, Hidefumi Waki, Masayasu Miyajima, Masanobu Maeda, Hitoshi Kikutani, Atsushi Kumanogoh

JOURNAL OF PHYSIOLOGICAL SCIENCES　Vol. 59　No. 3　p. 483-483　2009年

Immune semaphorins: novel features of neural guidance molecules.

Masayuki Mizui, Atsushi Kumanogoh, Hitoshi Kikutani

Journal of clinical immunology　Vol. 29　No. 1　p. 1-11　2009年1月　研究論文（学術雑誌）

Plexin A3 and plexin A4 convey semaphorin signals during facial nerve development.

Schwarz Q, Waimey KE, Golding M, Takamatsu H, Kumanogoh A, Fujisawa H, Cheng HJ, Ruhrberg C

Developmental biology　Vol. 324　No. 1　p. 1-9　2008年12月1日　研究論文（学術雑誌）

Involvement of Sema4A in the progression of experimental autoimmune myocarditis.

Nobuhiko Makino, Toshihiko Toyofuku, Noriko Takegahara, Hyota Takamatsu, Tatsusada Okuno, Yukinobu Nakagawa, Sujin Kang, Satoshi Nojima, Masatsugu Hori, Hitoshi Kikutani, Atsushi Kumanogoh

FEBS letters　Vol. 582　No. 28　p. 3935-40　2008年11月26日　研究論文（学術雑誌）

Repulsive and attractive semaphorins cooperate to direct the navigation of cardiac neural crest cells.

Toyofuku T, Yoshida J, Sugimoto T, Yamamoto M, Makino N, Takamatsu H, Takegahara N, Suto F, Hori M, Fujisawa H, Kumanogoh A, Kikutani H

Developmental biology　Vol. 321　No. 1　p. 251-62　2008年9月1日　研究論文（学術雑誌）

Edaravone, a free radical scavenger, ameliorates experimental autoimmune encephalomyelitis.

Masayuki Moriya, Yuji Nakatsuji, Katsuichi Miyamoto, Tatsusada Okuno, Makoto Kinoshita, Atsushi Kumanogoh, Susumu Kusunoki, Saburo Sakoda

Neuroscience letters　Vol. 440　No. 3　p. 323-6　2008年8月8日　研究論文（学術雑誌）

Tumor angiogenesis and progression are enhanced by Sema4D produced by tumor-associated macrophages.

Sierra JR, Corso S, Caione L, Cepero V, Conrotto P, Cignetti A, Piacibello W, Kumanogoh A, Kikutani H, Comoglio PM, Tamagnone L, Giordano S

The Journal of experimental medicine　Vol. 205　No. 7　p. 1673-85　2008年7月7日

Bimodal regulation of T cell-mediated immune responses by TIM-4.

Masayuki Mizui, Takashi Shikina, Hisashi Arase, Kazuhiro Suzuki, Teruhito Yasui, Paul D Rennert, Atsushi Kumanogoh, Hitoshi Kikutani

International immunology　Vol. 20　No. 5　p. 695-708　2008年5月　研究論文（学術雑誌）

Plexin-A4 negatively regulates T lymphocyte responses.

Midori Yamamoto, Kazuhiro Suzuki, Tatsusada Okuno, Takehiro Ogata, Noriko Takegahara, Hyota Takamatsu, Masayuki Mizui, Masahiko Taniguchi, Alain Chédotal, Fumikazu Suto, Hajime Fujisawa, Atsushi Kumanogoh, Hitoshi Kikutani

International immunology　Vol. 20　No. 3　p. 413-20　2008年3月　研究論文（学術雑誌）

Semaphorins and their receptors in immune cell interactions.

Suzuki K, Kumanogoh A, Kikutani H

Nature immunology　Vol. 9　No. 1　p. 17-23　2008年1月

A novel role for the semaphorin Sema4D in the induction of allo-responses.

Duran-Struuck R, Tawara I, Lowler K, Clouthier SG, Weisiger E, Rogers C, Luker G, Kumanogoh A, Liu C, Ferrara JL, Reddy P

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation　Vol. 13　No. 11　p. 1294-1303　2007年11月

CD83 influences cell-surface MHC class II expression on B cells and other antigen-presenting cells.

Kuwano Y, Prazma CM, Yazawa N, Watanabe R, Ishiura N, Kumanogoh A, Okochi H, Tamaki K, Fujimoto M, Tedder TF

International immunology　Vol. 19　No. 8　p. 977-92　2007年8月　研究論文（学術雑誌）

Tim2 is expressed in mouse fetal hepatocytes and regulates their differentiation.

Watanabe N, Tanaka M, Suzuki K, Kumanogoh A, Kikutani H, Miyajima A

Hepatology (Baltimore, Md.)　Vol. 45　No. 5　p. 1240-9　2007年5月

Semaphorin 7A initiates T-cell-mediated inflammatory responses through alpha1beta1 integrin.

Suzuki K, Okuno T, Yamamoto M, Pasterkamp RJ, Takegahara N, Takamatsu H, Kitao T, Takagi J, Rennert PD, Kolodkin AL, Kumanogoh A, Kikutani H

Nature　Vol. 446　No. 7136　p. 680-4　2007年4月5日　研究論文（学術雑誌）

Semaphorin-4A, an activator for T-cell-mediated immunity, suppresses angiogenesis via Plexin-D1.

Toyofuku T, Yabuki M, Kamei J, Kamei M, Makino N, Kumanogoh A, Hori M

The EMBO journal　Vol. 26　No. 5　p. 1373-84　2007年3月7日　研究論文（学術雑誌）

Serum chemokine profile in patients with bullous pemphigoid

H. Nakashima, M. Fujimoto, N. Asashima, R. Watanabe, Y. Kuwano, N. Yazawa, N. Maruyama, H. Okochi, A. Kumanogoh, K. Tamaki

BRITISH JOURNAL OF DERMATOLOGY　Vol. 156　No. 3　p. 454-459　2007年3月　研究論文（学術雑誌）

Regulated surface expression and shedding support a dual role for semaphorin 4D in platelet responses to vascular injury.

Zhu L, Bergmeier W, Wu J, Jiang H, Stalker TJ, Cieslak M, Fan R, Boumsell L, Kumanogoh A, Kikutani H, Tamagnone L, Wagner DD, Milla ME, Brass LF

Proceedings of the National Academy of Sciences of the United States of America　Vol. 104　No. 5　p. 1621-6　2007年1月30日

Immune semaphorins: increasing members and their diverse roles.

Kikutani H, Suzuki K, Kumanogoh A

Advances in immunology　Vol. 93　p. 121-43　2007年

CD100 enhances dendritic cell and CD4+ cell activation leading to pathogenetic humoral responses and immune complex glomerulonephritis.

Li M, O'Sullivan KM, Jones LK, Semple T, Kumanogoh A, Kikutani H, Holdsworth SR, Kitching AR

Journal of immunology (Baltimore, Md. : 1950)　Vol. 177　No. 5　p. 3406-12　2006年9月1日

Plexin-A1 and its interaction with DAP12 in immune responses and bone homeostasis.

Noriko Takegahara, Hyota Takamatsu, Toshihiko Toyofuku, Tohru Tsujimura, Tatsusada Okuno, Kazunori Yukawa, Masayuki Mizui, Midori Yamamoto, Durbaka V R Prasad, Kazuhiro Suzuki, Masaru Ishii, Kenta Terai, Masayuki Moriya, Yuji Nakatsuji, Saburo Sakoda, Shintaro Sato, Shizuo Akira, Kiyoshi Takeda, Masanori Inui, Toshiyuki Takai, Masahito Ikawa, Masaru Okabe, Atsushi Kumanogoh, Hitoshi Kikutani

Nature cell biology　Vol. 8　No. 6　p. 615-22　2006年6月　研究論文（学術雑誌）

[Semaphorins in immune responses: involvement of Sema4A in T-cell priming and Th1/Th2 regulation].

Suzuki K, Kumanogoh A

Seikagaku. The Journal of Japanese Biochemical Society　Vol. 78　No. 2　p. 141-5　2006年2月

FARP2 triggers signals for Sema3A-mediated axonal repulsion.

Toyofuku T, Yoshida J, Sugimoto T, Zhang H, Kumanogoh A, Hori M, Kikutani H

Nature neuroscience　Vol. 8　No. 12　p. 1712-9　2005年12月　研究論文（学術雑誌）

Requirement for CD100-CD72 interactions in fine-tuning of B-cell antigen receptor signaling and homeostatic maintenance of the B-cell compartment.

Atsushi Kumanogoh, Takashi Shikina, Chie Watanabe, Noriko Takegahara, Kazuhiro Suzuki, Midori Yamamoto, Hyota Takamatsu, Durbaka V R Prasad, Masayuki Mizui, Toshihiko Toyofuku, Manabu Tamura, Dai Watanabe, Jane R Parnes, Hitoshi Kikutani

International immunology　Vol. 17　No. 10　p. 1277-82　2005年10月　研究論文（学術雑誌）

[Involvement of semaphorins in autoimmunity].

Takamatsu H, Kumanogoh A

Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology　Vol. 28　No. 5　p. 327-32　2005年10月　研究論文（学術雑誌）

Semaphorins: a new class of immunoregulatory molecules.

Takegahara N, Kumanogoh A, Kikutani H

Philosophical transactions of the Royal Society of London. Series B, Biological sciences　Vol. 360　No. 1461　p. 1673-80　2005年9月29日

Loss of dopaminergic neurons by the induction of inducible nitric oxide synthase and cyclooxygenase-2 via CD 40: relevance to Parkinson's disease.

Tatsusada Okuno, Yuji Nakatsuji, Atsushi Kumanogoh, Masayuki Moriya, Hiroshi Ichinose, Hisae Sumi, Harutoshi Fujimura, Hitoshi Kikutani, Saburo Sakoda

Journal of neuroscience research　Vol. 81　No. 6　p. 874-82　2005年9月15日　研究論文（学術雑誌）

Semaphorin 4A induces growth cone collapse of hippocampal neurons in a Rho/Rho-kinase-dependent manner.

Yukawa K, Tanaka T, Bai T, Ueyama T, Owada-Makabe K, Tsubota Y, Maeda M, Suzuki K, Kikutani H, Kumanogoh A

International journal of molecular medicine　Vol. 16　No. 1　p. 115-8　2005年7月　研究論文（学術雑誌）

[Involvement of semaphorins in immunoregulation].

Masayuki Mizui, Atsushi Kumanogoh

Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology　Vol. 28　No. 3　p. 109-16　2005年6月　研究論文（学術雑誌）

Nonredundant roles of Sema4A in the immune system: defective T cell priming and Th1/Th2 regulation in Sema4A-deficient mice.

Atsushi Kumanogoh, Takashi Shikina, Kazuhiro Suzuki, Satoshi Uematsu, Kazunori Yukawa, Shin-Ichiro Kashiwamura, Hiroko Tsutsui, Midori Yamamoto, Hyota Takamatsu, Elizabeth P Ko-Mitamura, Noriko Takegahara, Satoko Marukawa, Isao Ishida, Hiroshi Morishita, Durbaka V R Prasad, Manabu Tamura, Masayuki Mizui, Toshihiko Toyofuku, Shizuo Akira, Kiyoshi Takeda, Masaru Okabe, Hitoshi Kikutani

Immunity　Vol. 22　No. 3　p. 305-16　2005年3月　研究論文（学術雑誌）

Guidance of myocardial patterning in cardiac development by Sema6D reverse signalling.

Toyofuku T, Zhang H, Kumanogoh A, Takegahara N, Yabuki M, Harada K, Hori M, Kikutani H

Nature cell biology　Vol. 6　No. 12　p. 1204-11　2004年12月　研究論文（学術雑誌）

Woodchuck interleukin-6 gene: structure, characterization, and biologic activity.

Li DH, Kumanogoh A, Cao TM, Parnes JR, Cullen JM

Gene　Vol. 342　No. 1　p. 157-64　2004年11月10日

Induction of cyclooxygenase-2 in reactive glial cells by the CD40 pathway: relevance to amyotrophic lateral sclerosis.

Tatsusada Okuno, Yuji Nakatsuji, Atsushi Kumanogoh, Ken Koguchi, Masayuki Moriya, Harutoshi Fujimura, Hitoshi Kikutani, Saburo Sakoda

Journal of neurochemistry　Vol. 91　No. 2　p. 404-12　2004年10月　研究論文（学術雑誌）

Dual roles of Sema6D in cardiac morphogenesis through region-specific association of its receptor, Plexin-A1, with off-track and vascular endothelial growth factor receptor type 2.

Toyofuku T, Zhang H, Kumanogoh A, Takegahara N, Suto F, Kamei J, Aoki K, Yabuki M, Hori M, Fujisawa H, Kikutani H

Genes & development　Vol. 18　No. 4　p. 435-47　2004年2月15日　研究論文（学術雑誌）

The transmembrane semaphorin Sema4D/CD100, an inhibitor of axonal growth, is expressed on oligodendrocytes and upregulated after CNS lesion.

Moreau-Fauvarque C, Kumanogoh A, Camand E, Jaillard C, Barbin G, Boquet I, Love C, Jones EY, Kikutani H, Lubetzki C, Dusart I, Chédotal A

The Journal of neuroscience : the official journal of the Society for Neuroscience　Vol. 23　No. 27　p. 9229-39　2003年10月8日

Immune semaphorins: a new area of semaphorin research.

Kumanogoh A, Kikutani H

Journal of cell science　Vol. 116　No. Pt 17　p. 3463-70　2003年9月1日

Involvement of CD100, a lymphocyte semaphorin, in the activation of the human immune system via CD72: implications for the regulation of immune and inflammatory responses.

Ishida I, Kumanogoh A, Suzuki K, Akahani S, Noda K, Kikutani H

International immunology　Vol. 15　No. 8　p. 1027-34　2003年8月

CD100/Sema4D, a lymphocyte semaphorin involved in the regulation of humoral and cellular immune responses.

Suzuki K, Kumanogoh A, Kikutani H

Cytokine & growth factor reviews　Vol. 14　No. 1　p. 17-24　2003年2月

Semaphorins in interactions between T cells and antigen-presenting cells.

Kikutani H, Kumanogoh A

Nature reviews. Immunology　Vol. 3　No. 2　p. 159-67　2003年2月

Roles of the semaphorin family in immune regulation.

Kumanogoh A, Kikutani H

Advances in immunology　Vol. 81　p. 173-98　2003年

[Involvement of immune semaphorins in the immune system].

Kumanogoh A

Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme　Vol. 47　No. 16 Suppl　p. 2254-60　2002年12月

Requirement for the lymphocyte semaphorin, CD100, in the induction of antigen-specific T cells and the maturation of dendritic cells.

Kumanogoh A, Suzuki K, Ch'ng E, Watanabe C, Marukawa S, Takegahara N, Ishida I, Sato T, Habu S, Yoshida K, Shi W, Kikutani H

Journal of immunology (Baltimore, Md. : 1950)　Vol. 169　No. 3　p. 1175-81　2002年8月1日

Dissection of B cell differentiation during primary immune responses in mice with altered CD40 signals.

Yasui T, Muraoka M, Takaoka-Shichijo Y, Ishida I, Takegahara N, Uchida J, Kumanogoh A, Suematsu S, Suzuki M, Kikutani H

International immunology　Vol. 14　No. 3　p. 319-29　2002年3月