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リゾリン脂質輸送体と疾患制御
小林 直木, 久野 悠, 西 毅
医学のあゆみ Vol. 269 No. 13 p. 1082-1088 2019年6月 研究論文(学術雑誌)
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A human ABC transporter ABCC4 gene SNP (rs11568658, 559 G>T, G187W) reduces ABCC4-dependent drug resistance
M. Tsukamoto, M. Yamashita, S. Sato, T. Nishi, H. Nakagawa
Cells Vol. 8 2019年1月 研究論文(学術雑誌)
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MFSD2B is a sphingosine 1-phosphate transporter in erythroid cells
Naoki Kobayashi, Shoko Kawasaki-Nishi, Masato Otsuka, Yu Hisano, Akihito Yamaguchi, Tsuyoshi Nishi
Scientific Reports Vol. 8 No. 1 2018年12月1日 研究論文(学術雑誌)
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新たに同定された赤血球のS1P輸送体MFSD2B
小林 直木, 西, 川崎)晶子, 西 毅
生化学 2018年10月
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MFSD2B is a novel sphingosine 1-phosphate transporter in erythroid cells
N. Kobayashi, S.Kawasaki-Nishi, M. Otsuka, Y. Hisano, A. Yamaguchi, T. Nishi
2018年9月
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MFSD2B mediates sphingosine 1-phosphate export from erythroid cells
N. Kobayashi, S.Kawasaki-Nishi, M. Otsuka, Y. Hisano, A. Yamaguchi, T. Nishi
2018年9月
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A rapid fluorescence assay for measuring sphingosine-1-phosphate transporter activity in erythrocytes
Naoki Kobayashi, Tsuyoshi Nishi
Methods in Molecular Biology Vol. 1697 p. 73-82 2018年 論文集(書籍)内論文
出版者・発行元:Humana Press Inc.
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Fluorescence-based rapid measurement of sphingosine-1-phosphate transport activity in erythrocytes
Naoki Kobayashi, Masato Otsuka, Akihito Yamaguchi, Tsuyoshi Nishi
JOURNAL OF LIPID RESEARCH Vol. 57 No. 11 p. 2088-2094 2016年11月 研究論文(学術雑誌)
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新しい創薬標的としての脂質メディエーター分泌輸送体
西 毅, 久野 悠, 小林 直木, 山口 明人
実験医学 Vol. 34 p. 2356-2361 2016年9月
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Molecular and physiological functions of sphingosine 1-phosphate transporters
Tsuyoshi Nishi, Naoki Kobayashi, Yu Hisano, Atsuo Kawahara, Akihito Yamaguchi
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS Vol. 1841 No. 5 p. 759-765 2014年5月
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Functional and Physiological Roles of Sphingosine 1-Phosphate Transporters
Atsuo Kawahara, Tsuyoshi Nishi
Lysophospholipid Receptors: Signaling and Biochemistry p. 185-200 2013年2月19日 論文集(書籍)内論文
出版者・発行元:John Wiley and Sons
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The functional roles of S1P in immunity
Yu Hisano, Tsuyoshi Nishi, Atsuo Kawahara
JOURNAL OF BIOCHEMISTRY Vol. 152 No. 4 p. 305-311 2012年10月 研究論文(学術雑誌)
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Mouse SPNS2 Functions as a Sphingosine-1-Phosphate Transporter in Vascular Endothelial Cells
Yu Hisano, Naoki Kobayashi, Akihito Yamaguchi, Tsuyoshi Nishi
PLOS ONE Vol. 7 No. 6 2012年6月 研究論文(学術雑誌)
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Phosphopeptide-Dependent Labeling of 14-3-3?? Proteins by Fusicoccin-Based Fluorescent Probes
Michiko Takahashi, Akie Kawamura, Nobuo Kato, Tsuyoshi Nishi, Itaru Hamachi, Junko Ohkanda
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION Vol. 51 No. 2 p. 509-512 2012年 研究論文(学術雑誌)
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Isoform selective and phosphopeptide-dependent 14-3-3 zeta labeling by fusicoccins
J. Ohkanda, M. Takahashi, A. Kawamura, I. Hamachi, T. Nishi, N. Kato
2011年1月
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The Sphingosine 1-Phosphate Transporter, SPNS2, Functions as a Transporter of the Phosphorylated Form of the Immunomodulating Agent FTY720
Yu Hisano, Naoki Kobayashi, Atsuo Kawahara, Akihito Yamaguchi, Tsuyoshi Nishi
JOURNAL OF BIOLOGICAL CHEMISTRY Vol. 286 No. 3 p. 1758-1766 2011年1月 研究論文(学術雑誌)
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The analysis of sphingosine 1-phosphate secretion from cells expressing Spns2.
Y. Hisano, A. Yamaguchi, T. Nish
2010年9月
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Macrophage ABCA5 deficiency influences cellular cholesterol efflux and increases susceptibility to atherosclerosis in female LDLr knockout mice
Dan Ye, Illiana Meurs, Megumi Ohigashi, Laura Calpe-Berdiel, Kim L. L. Habets, Ying Zhao, Yoshiyuki Kubo, Akihito Yamaguchi, Theo J. C. Van Berkel, Tsuyoshi Nishi, Miranda Van Eck
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS Vol. 395 No. 3 p. 387-394 2010年5月 研究論文(学術雑誌)
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Characterization of the ATP-dependent Sphingosine 1-Phosphate Transporter in Rat Erythrocytes
Naoki Kobayashi, Nobuyoshi Kobayashi, Akihito Yamaguchi, Tsuyoshi Nishi
JOURNAL OF BIOLOGICAL CHEMISTRY Vol. 284 No. 32 p. 21192-21200 2009年8月 研究論文(学術雑誌)
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The Sphingolipid Transporter Spns2 Functions in Migration of Zebrafish Myocardial Precursors
Atsuo Kawahara, Tsuyoshi Nishi, Yu Hisano, Hajime Fukui, Akihito Yamaguchi, Naoki Mochizuki
SCIENCE Vol. 323 No. 5913 p. 524-527 2009年1月 研究論文(学術雑誌)
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Neuronal expression of the ATP Binding Cassette transporter, ABCA5
Megumi Ohigashi, Tsuyoshi Nishi, Akihito Yamaguchi
YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN Vol. 128 p. 25-26 2008年
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Identification of the S1P transporter in PLPs derived form the MEG-01 cells treated with siRNA
Yu Hisano, Tsuyoshi Nishi, Akihito Yamaguchi
YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN Vol. 128 p. 27-28 2008年
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Secretion mechanism of the lipophilic cell signaling molecule from the cells
Tsuyoshi Nishi, Naoki Kobayashi, Akihito Yamaguchi
YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN Vol. 128 p. 63-64 2008年
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Tissue specific expression of the splicing variants of the mouse vacuolar proton-translocating ATPase a4 subunit.
Kawasaki-Nishi, S, Yamaguchi, A, Forgac, M, Nishi, T
Biochem. Biophys. Res. Commun. Vol. 364 No. 4 p. 1032-1036 2007年12月 研究論文(学術雑誌)
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ラット赤血球におけるスフィンゴシン1リン酸輸送機構の同定
小林直木, 小林伸好, 西毅, 山口明人
薬学雑誌 Vol. 127 No. Supple. 5 p. 29-30 2007年11月 研究論文(学術雑誌)
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Identification of the function of ABCA7 in mouse platelets
Mamiko Onoe, Sakiko Shibata, Tsuyoshi Nishi, Akihito Yamaguchi
YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN Vol. 127 p. 31-32 2007年
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Expression and cellular localization of ABCA6 in mouse liver
Kosuke Miyata, Megumi Ohigashi, Tsuyoshi Nishi, Akihito Yamaguchi
YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN Vol. 127 p. 33-34 2007年
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Sphingosine 1-phosphate is released from the cytosol of rat platelets in a carrier-mediated manner.
Nobuyoshi Kobayashi, Tsuyoshi Nishi, Takahiro Hirata, Akio Kihara, Takamitsu Sano, Yasuyuki Igarashi, Akihito Yamaguchi
Journal of lipid research Vol. 47 No. 3 p. 614-21 2006年3月 研究論文(学術雑誌)
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Erratum: ABCA5 resides in lysosomes, and ABCA5 knockout mice develop lysosomal disease-like symptoms (Molecular and Cellular Biology (2005) 25, 10 (4138-4149))
Yoshiyuki Kubo, Sayaka Sekiya, Megumi Ohigashi, Chiemi Takenaka, Kyoko Tamura, Shigeyuki Nada, Tsuyoshi Nishi, Akitsugu Yamamoto, Akihito Yamaguchi
Molecular and Cellular Biology Vol. 25 No. 13 2005年7月 研究論文(学術雑誌)
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ABCA5 resides in lysosomes, and ABCA5 knockout mice develop lysosomal disease-like symptoms
Y Kubo, S Sekiya, M Ohigashi, C Takenaka, K Tamura, S Nada, T Nishi, A Yamamoto, A Yamaguchi
MOLECULAR AND CELLULAR BIOLOGY Vol. 25 No. 10 p. 4138-4149 2005年5月 研究論文(学術雑誌)
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サブユニットアイソフォームによるV-ATPaseの局在と活性の制御
西 毅
生化学 Vol. 77 No. 4 p. 354-358 2005年4月
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精巧で巧妙な仕組みを持つプロトンポンプ、V 型 ATPase
横山 謙, 西 毅
蛋白質 核酸 酵素 Vol. 49 p. 2035-2043 2004年
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Expression and function of the mouse V-ATPase d subunit isoforms
T Nishi, SK Nishi, M Forgac
JOURNAL OF BIOLOGICAL CHEMISTRY Vol. 278 No. 47 p. 46396-46402 2003年11月 研究論文(学術雑誌)
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Interacting helical surfaces of the transmembrane segments of subunits a and c’ of the yeast V-ATPase defined by disulfide-mediated cross-linking.
Kawasaki-Nishi S, Nishi T, Forgac M
J. Biol. Chem. Vol. 278 No. 43 p. 41908-41913 2003年10月 研究論文(学術雑誌)
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Proton translocation driven by ATP hydrolysis in V-ATPases
S Kawasaki-Nishi, T Nishi, M Forgac
FEBS LETTERS Vol. 545 No. 1 p. 76-85 2003年6月
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Mutational analysis of the non-homologous region of subunit a of the yeast V-ATPase
E Shao, T Nishi, S Kawasaki-Nishi, M Forgac
JOURNAL OF BIOLOGICAL CHEMISTRY Vol. 278 No. 15 p. 12985-12991 2003年4月 研究論文(学術雑誌)
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The first putative transmembrane segment of subunit c” (Vma16p) of the yeast V-ATPase is not necessary for function.
Nishi T, Kawasaki-Nishi S, Forgac M
J. Biol. Chem. Vol. 278 No. 8 p. 5821-5827 2003年2月 研究論文(学術雑誌)
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Structure, subunit function and regulation of the coated vesicle and yeast vacuolar (H+)-ATPases
Y Arata, T Nishi, S Kawasaki-Nishi, E Shao, S Wilkens, M Forgac
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS Vol. 1555 No. 1-3 p. 71-74 2002年9月 研究論文(学術雑誌)
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Structure, subunit function and regulation of the coated vesicle and yeast vacuolar (H(+))-ATPases.
Arata Y, Nishi T, Kawasaki-Nishi S, Shao E, Wilkens S, Forgac M
Biochimica et biophysica acta Vol. 1555 No. 1-3 p. 71-74 2002年9月
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The vacuolar (H+)-ATPase―Nature’s most versatile proton pumps.
Nishi T, Forgac M
Nature Reviews Mol. Cell Biol. Vol. 3 No. 2 p. 94-103 2002年2月
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The amino-terminal domain of the vacuolar proton-translocating ATPase a subunit controls targeting and in vivo dissociation, and the carboxyl-terminal domain affects coupling of proton transport and ATP hydrolysis
S Kawasaki-Nishi, K Bowers, T Nishi, M Forgac, TH Stevens
JOURNAL OF BIOLOGICAL CHEMISTRY Vol. 276 No. 50 p. 47411-47420 2001年12月 研究論文(学術雑誌)
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Arg-735 of the 100-kDa subunit a of the yeast V-ATPase is essential for proton translocation
S Kawasaki-Nishi, T Nish, M Forgac
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA Vol. 98 No. 22 p. 12397-12402 2001年10月 研究論文(学術雑誌)
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Expression and localization of the mouse homologue of the yeast V-ATPase 21 kDa subunit c” (Vma16p).
Nishi T, Kawasaki-Nishi S, Forgac M
J. Biol. Chem. Vol. 276 No. 36 p. 34122-34130 2001年9月 研究論文(学術雑誌)
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Yeast V-ATPase complexes containing different isoforms of the 100-kDa a-subunit differ in coupling efficiency and in vivo dissociation
S Kawasaki-Nishi, T Nishi, M Forgac
JOURNAL OF BIOLOGICAL CHEMISTRY Vol. 276 No. 21 p. 17941-17948 2001年5月 研究論文(学術雑誌)
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Molecular cloning and expression of three isoforms of the 100-kDa a subunit of the mouse vacuolar proton-translocating ATPase
T Nishi, M Forgac
JOURNAL OF BIOLOGICAL CHEMISTRY Vol. 275 No. 10 p. 6824-6830 2000年3月 研究論文(学術雑誌)
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Human histamine H2 receptor gene: multiple transcription initiation and tissue-specific expression
H Murakami, GH Sun-Wada, M Matsumoto, T Nishi, Y Wada, M Futai
FEBS LETTERS Vol. 451 No. 3 p. 327-331 1999年5月 研究論文(学術雑誌)
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Transmembrane topography of the 100-kDa a subunit (Vph1p) of the yeast vacuolar proton translocating ATPase
XH Leng, T Nishi, M Forgac
JOURNAL OF BIOLOGICAL CHEMISTRY Vol. 274 No. 21 p. 14655-14661 1999年5月 研究論文(学術雑誌)
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Metabotropic glutamate receptors negatively regulate melatonin synthesis in rat pinealocytes
H Yamada, S Yatsushiro, S Ishio, M Hayashi, T Nishi, A Yamamoto, M Futai, A Yamaguchi, Y Moriyama
JOURNAL OF NEUROSCIENCE Vol. 18 No. 6 p. 2056-2062 1998年3月 研究論文(学術雑誌)
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Functional expression of a GLT-1 type Na+-dependent glutamate transporter in rat pinealocytes
H Yamada, S Yatsushiro, A Yamamoto, M Hayashi, T Nishi, M Futai, A Yamaguchi, Y Moriyama
JOURNAL OF NEUROCHEMISTRY Vol. 69 No. 4 p. 1491-1498 1997年10月 研究論文(学術雑誌)
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Transcriptional activation of H+/K+-ATPase genes by gastric GATA binding proteins
T Nishi, K Kubo, M Hasebe, M Maeda, M Futai
JOURNAL OF BIOCHEMISTRY Vol. 121 No. 5 p. 922-929 1997年5月 研究論文(学術雑誌)
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胃粘膜壁細胞のプロトンポンプとその発現調節
西 毅, 二井 將光
臨床科学 Vol. 33 p. 611-617 1997年
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Roles of gastric GATA DNA-binding proteins
M Maeda, K Kubo, T Nishi, M Futai
JOURNAL OF EXPERIMENTAL BIOLOGY Vol. 199 No. 3 p. 513-520 1996年3月
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THE RAT INTRINSIC-FACTOR GENE - ITS 5'-UPSTREAM REGION AND CHIEF CELL-SPECIFIC TRANSCRIPTION
M MAEDA, S ASAHARA, T NISHI, S MUSHIAKE, T OKA, S SHIMADA, T CHIBA, M TOHYAMA, M FUTAI
JOURNAL OF BIOCHEMISTRY Vol. 117 No. 6 p. 1305-1311 1995年6月 研究論文(学術雑誌)
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IDENTIFICATION OF THE PROMOTER REGION OF THE HUMAN HISTAMINE-H2-RECEPTOR GENE
T NISHI, T KOIKE, T OKA, M MAEDA, M FUTAI
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS Vol. 210 No. 2 p. 616-623 1995年5月 研究論文(学術雑誌)
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SEQUENCE MOTIF IN CONTROL REGIONS OF THE H+/K+ ATPASE ALPHA-SUBUNIT AND BETA-SUBUNIT GENES RECOGNIZED BY GASTRIC SPECIFIC NUCLEAR PROTEIN(S)
S TAMURA, KI OSHIMAN, T NISHI, M MORI, M MAEDA, M FUTAI
FEBS LETTERS Vol. 298 No. 2-3 p. 137-141 1992年2月 研究論文(学術雑誌)
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ATP-DEPENDENT TRANSPORT FOR GLUCURONIDES IN CANALICULAR PLASMA-MEMBRANE VESICLES
K KOBAYASHI, S KOMATSU, T NISHI, H HARA, K HAYASHI
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS Vol. 176 No. 2 p. 622-626 1991年4月 研究論文(学術雑誌)