EN

基本情報

研究

社会活動

その他の活動

藤尾 慈

Fujio Yasushi

薬学研究科 医療薬学専攻,教授

研究内容・専門分野

  • ライフサイエンス,薬理学,病態薬理学

所属学会

  • 日本薬学会
  • 日本循環薬理学会
  • 日本心臓病学会
  • 日本心不全学会
  • アメリカ心臓協会
  • 日本臨床薬理学会
  • 日本薬理学会
  • 日本循環器学会
  • 日本内科学会

論文

  • Title: Gene transfer by pyro-drive jet injector is a novel therapeutic approach for muscle diseases,Takafumi Nakae,Masanori Obana,Takahiro Maeda,Akari Ikeda,Hiroshi Miyazaki,Shota Tanaka,Makiko Maeda,Kunihiko Yamashita,Kazuhiro Terai,Satoshi Obika,Yasushi Fujio,Gene,Elsevier BV,Vol. 788,p. 145664-145664,2021年07月,研究論文(学術雑誌)
  • Adenovirus Vector–Induced IL-6 Promotes Leaky Adenoviral Gene Expression, Leading to Acute Hepatotoxicity,Kahori Shimizu,Fuminori Sakurai,Shunsuke Iizuka,Ryosuke Ono,Tomohito Tsukamoto,Fumitaka Nishimae,Shin-ichiro Nakamura,Toru Nishinaka,Tomoyuki Terada,Yasushi Fujio,Hiroyuki Mizuguchi,The Journal of Immunology,The American Association of Immunologists,Vol. 206,No. 2,p. 410-421,2021年01月15日,研究論文(学術雑誌)
  • Transcription factor old astrocyte specifically induced substance is a novel regulator of kidney fibrosis.,Ayaha Yamamoto,Hitomi Morioki,Takafumi Nakae,Yoshiaki Miyake,Takeo Harada,Shunsuke Noda,Sayuri Mitsuoka,Kotaro Matsumoto,Masashi Tomimatsu,Soshi Kanemoto,Shota Tanaka,Makiko Maeda,Simon J Conway,Kazunori Imaizumi,Yasushi Fujio,Masanori Obana,FASEB journal : official publication of the Federation of American Societies for Experimental Biology,2020年11月05日,研究論文(学術雑誌)
  • Thorough QT/QTc Study Shows That a Novel 5-HT4 Receptor Partial Agonist Minesapride Has No Effect on QT Prolongation.,Tatsuto Hamatani,Naoto Noda,Takeshi Takagaki,Yasuhide Yodo,Hirotaka Kawai,Hiroyoshi Kakuyama,Yoshikazu Kaji,Yasushi Fujio,Clinical pharmacology in drug development,Vol. 9,No. 8,p. 938-951,2020年11月,研究論文(学術雑誌)
  • β2-adrenergic stimulation induces interleukin-6 by increasing Arid5a, a stabilizer of mRNA, through cAMP/PKA/CREB pathway in cardiac fibroblasts.,Shota Tanaka,Atsuki Imaeda,Kotaro Matsumoto,Makiko Maeda,Masanori Obana,Yasushi Fujio,Pharmacology research & perspectives,Vol. 8,No. 2,2020年04月,研究論文(学術雑誌)
  • [Preface].,Yasushi Fujio,Jong-Kook Lee,Nihon yakurigaku zasshi. Folia pharmacologica Japonica,Vol. 155,No. 5,p. 299-299,2020年,研究論文(学術雑誌)
  • The CalcR-PKA-Yap1 Axis Is Critical for Maintaining Quiescence in Muscle Stem Cells.,Zhang L,Noguchi YT,Nakayama H,Kaji T,Tsujikawa K,Ikemoto-Uezumi M,Uezumi A,Okada Y,Doi T,Watanabe S,Braun T,Fujio Y,Fukada SI,Cell reports,Vol. 29,No. 8,p. 2154-2163.e5,2019年11月
  • Verification of pharmacogenomics-based algorithms to predict warfarin maintenance dose using registered data of Japanese patients.,Sasano M,Ohno M,Fukuda Y,Nonen S,Hirobe S,Maeda S,Miwa Y,Yokoyama J,Nakayama H,Miyagawa S,Sawa Y,Fujio Y,Maeda M,European journal of clinical pharmacology,Vol. 75,No. 7,p. 901-911,2019年07月
  • Myofibroblast β2 adrenergic signaling amplifies cardiac hypertrophy in mice.,Imaeda A,Tanaka S,Tonegawa K,Fuchigami S,Obana M,Maeda M,Kihara M,Kiyonari H,Conway SJ,Fujio Y,Nakayama H,Biochemical and biophysical research communications,Vol. 510,No. 1,p. 149-155,2019年02月
  • Old-Age Onset Progressive Cardiac Contractile Dysfunction in a Patient with Polycystic Kidney Disease Harboring a PKD1 Frameshift Mutation.,Suwa Y,Higo S,Nakamoto K,Sera F,Kunimatsu S,Masumura Y,Kanzaki M,Mizote I,Mizuno H,Fujio Y,Hikoso S,Sakata Y,International heart journal,Vol. 60,No. 1,p. 220-225,2019年01月
  • The Robo4-TRAF7 complex suppresses endothelial hyperpermeability in inflammation.,Shirakura K,Ishiba R,Kashio T,Funatsu R,Tanaka T,Fukada SI,Ishimoto K,Hino N,Kondoh M,Ago Y,Fujio Y,Yano K,Doi T,Aird WC,Okada Y,Journal of cell science,Vol. 132,No. 1,2019年01月
  • Eukaryotic translation initiation factor 3 subunit C is associated with acquired resistance to erlotinib in non-small cell lung cancer.,Takuya Shintani,Kazuma Higashisaka,Makiko Maeda,Masaya Hamada,Ryosuke Tsuji,Koudai Kurihara,Yuri Kashiwagi,Atsuhiro Sato,Masanori Obana,Ayaha Yamamoto,Keisuke Kawasaki,Ying Lin,Takashi Kijima,Yuhei Kinehara,Yoshihiro Miwa,Shinichiro Maeda,Eiichi Morii,Atsushi Kumanogoh,Yasuo Tsutsumi,Izumi Nagatomo,Yasushi Fujio,Oncotarget,Vol. 9,No. 101,p. 37520-37533,2018年12月25日
  • Blockade of NKG2D/NKG2D Ligand Interaction Attenuated Cardiac Remodeling after Myocardial Infarction.,Matsumoto K,Obana M,Kobayashi A,Kihara M,Shioi G,Miyagawa S,Maeda M,Sakata Y,Nakayama H,Sawa Y,Fujio Y,Cardiovascular research,2018年10月
  • Low-dose erythropoietin in patients with ST-segment elevation myocardial infarction (EPO-AMI-II): ― A randomized controlled clinical trial ―,Tetsuo Minamino,Shuichiro Higo,Ryo Araki,Shungo Hikoso,Daisaku Nakatani,Hiroshi Suzuki,Takahisa Yamada,Masaaki Okutsu,Kouji Yamamoto,Yasushi Fujio,Yoshio Ishida,Takuya Ozawa,Kiminori Kato,Ken Toba,Yoshifusa Aizawa,Issei Komuro,T. Toba,T. Ishimitsu,S. Higo,Y. Yasumura,T. Yamada,Y. Ueda,M. Nishino,H. Ito,H. Suzuki,A. Namiki,T. Tobaru,K. Ando,S. Yasuda,Y. Doi,S. Koba,M. Yasutake,Y. Akashi,S. Saito,M. Okutsu,Y. Kijima,T. Yoshida,N. Sato,Y. Sakai,Y. Ohira,EPO-AMI-II Investigators,Circulation Journal,Japanese Circulation Society,Vol. 82,No. 4,p. 1083-1091,2018年,研究論文(学術雑誌)
  • The cardioprotective effect of interleukin-11 against ischemia-reperfusion injury in a heart donor model,Yusaku Tamura,Hiroki Kohno,Tomomi Mohri,Yasushi Fujio,Goro Matsumiya,Annals of Cardiothoracic Surgery,AME Publishing Company,Vol. 7,No. 1,p. 99-105,2018年01月01日,研究論文(学術雑誌)
  • Caveolae-Specific CaMKII Signaling in the Regulation of Voltage-Dependent Calcium Channel and Cardiac Hypertrophy.,Tanaka S,Fujio Y,Nakayama H,Frontiers in physiology,Vol. 9,2018年
  • Sustained Activation of Guanylate Cyclase-A with TDT, a Natriuretic Peptide Derivative, Exhibits Cardiorenal Protection in Dahl Salt-Sensitive Hypertensive Rats,Shohei Oishi,Naoko Suzuki,Yuri Hasui,Tsuyoshi Homma,Masanori Obana,Takahiro Nagayama,Yasushi Fujio,JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS,AMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS,Vol. 363,No. 3,p. 402-410,2017年12月,研究論文(学術雑誌)
  • 2-aminoethoxydiphenyl borate provides an anti-oxidative effect and mediates cardioprotection during ischemia reperfusion in mice,Hirofumi Morihara,Masanori Obana,Shota Tanaka,Ikki Kawakatsu,Daisuke Tsuchiyama,Shota Mori,Hiroshi Suizu,Akiko Ishida,Rumi Kimura,Izuru Tsuchimochi,Makiko Maeda,Takehiko Yoshimitsu,Yasushi Fujio,Hiroyuki Nakayama,PLoS ONE,Public Library of Science,Vol. 12,No. 12,2017年12月01日,研究論文(学術雑誌)
  • Myofibroblast-Specific Deletion of Runx2 Improves Systolic Function and Survival in Late Phase of Cardiac Remodeling After Myocardial Infarction,Tanaka Shota,Enomoto Daichi,Yanase Emiko,Kumagai Shohei,Obana Masanori,Maeda Makiko,Fujio Yasushi,Nakayama Hiroyuki,CIRCULATION,Vol. 136,2017年11月14日
  • Safety and Feasibility Report of Investigational Therapy With Interleukin-11 Against Acute Myocardial Infarction,Maeda Makiko,Nakagawa Masaki,Owada Yasuko,Izumi Yasukatsu,Nonin Shinichi,Sugioka Kenichi,Nakatani Daisaku,Iwata Shinichi,Mizutani Kazuki,Nishimura Satoshi,Ito Asahiro,Fujita Suwako,Daimon Takashi,Sawa Yoshiki,Asakura Masanori,Fujio Yasushi,Yoshiyama Minoru,CIRCULATION,Vol. 136,2017年11月14日
  • RORγt-expressing cells attenuate cardiac remodeling after myocardial infarction.,Enomoto D,Matsumoto K,Yamashita T,Kobayashi A,Maeda M,Nakayama H,Obana M,Fujio Y,PloS one,Vol. 12,No. 8,2017年08月,研究論文(学術雑誌)
  • Phospholamban Inhibition by a Single Dose of Locked Nucleic Acid Antisense Oligonucleotide Improves Cardiac Contractility in Pressure Overload-Induced Systolic Dysfunction in Mice,Hirofumi Morihara,Tsuyoshi Yamamoto,Harunori Oiwa,Kota Tonegawa,Daisuke Tsuchiyama,Ikki Kawakatsu,Masanori Obana,Makiko Maeda,Tomomi Mohri,Satoshi Obika,Yasushi Fujio,Hiroyuki Nakayama,JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS,SAGE PUBLICATIONS INC,Vol. 22,No. 3,p. 273-282,2017年05月,研究論文(学術雑誌)
  • Mouse model of Epstein-Barr virus LMP1-and LMP2A-driven germinal center B-cell lymphoproliferative disease,Takeharu Minamitani,Yijie Ma,Hufeng Zhou,Hiroshi Kida,Chao-Yuan Tsai,Masanori Obana,Daisuke Okuzaki,Yasushi Fujio,Atsushi Kumanogoh,Bo Zhao,Hitoshi Kikutani,Elliott Kieff,Benjamin E. Gewurz,Teruhito Yasui,PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,NATL ACAD SCIENCES,Vol. 114,No. 18,p. 4751-4756,2017年05月,研究論文(学術雑誌)
  • Adult murine cardiomyocytes exhibit regenerative activity with cell cycle reentry through STAT3 in the healing process of myocarditis,Akimitsu Miyawaki,Masanori Obana,Yusuke Mitsuhara,Aya Orimoto,Yusuke Nakayasu,Tomomi Yamashita,So-ichiro Fukada,Makiko Maeda,Hiroyuki Nakayama,Yasushi Fujio,SCIENTIFIC REPORTS,NATURE PUBLISHING GROUP,Vol. 7,No. 1,2017年05月,研究論文(学術雑誌)
  • ROR gamma t heterozygous deficiency aggravates cardiac remodeling after myocardial infarction,Enomoto Daichi,Obana Masanori,Matsumoto Kotaro,Maeda Makiko,Nakayama Hiroyuki,Fujio Yasushi,JOURNAL OF PHARMACOLOGICAL SCIENCES,Vol. 133,No. 3,2017年03月
  • Fibroblast-specific PKA activation induces cardiac hypertrophy,Takahashi Misato,Tonegawa Kota,Fuchigami Shota,Tanaka Shota,Obana Masanori,Maeda Makiko,Fujio Yasushi,Nakayama Hiroyuki,JOURNAL OF PHARMACOLOGICAL SCIENCES,Vol. 133,No. 3,2017年03月
  • Elucidation of underlying mechanism of dynasore against ROS-induced CM death,Kawakatsu Ikki,Morihara Hirofumi,Kimura Rumi,Kubo Mikiko,Tsuchiyama Daisuke,Obana Masanori,Maeda Makiko,Fujio Yasushi,Nakayama Hiroyuki,JOURNAL OF PHARMACOLOGICAL SCIENCES,Vol. 133,No. 3,2017年03月
  • The deletion of Runx2 in fibroblasts has a protective role after MI,Yanase Emiko,Tanaka Shouta,Kumagai Shouhei,Enomoto Daichi,Nakayama Nami,Obana Masanori,Maeda Makiko,Fujio Yasushi,Nakayama Hiroyuki,JOURNAL OF PHARMACOLOGICAL SCIENCES,Vol. 133,No. 3,2017年03月
  • Moesin is activated in cardiomyocytes in experimental autoimmune myocarditis and mediates tissue restoration with protrusion formation,Mitsuhara Yusuke,Miyawaki Akimitsu,Orimoto Aya,Nakayasu Yusuke,Tsunoda Shin-ichi,Obana Masanori,Maeda Makiko,Nakayama Hiroyuki,Yoshioka Yasuo,Tsutsumi Yasuo,Fujio Yasushi,JOURNAL OF PHARMACOLOGICAL SCIENCES,Vol. 133,No. 3,2017年03月
  • eIF4B is a cytoprotective molecule downstream of Pim-1 kinase in cardiomyocytes,Yokoyama Yukari,Matsumoto Kotaro,Kinoshita Maki,Obana Masanori,Maeda Makiko,Nakayama Hiroyuki,Fujio Yasushi,JOURNAL OF PHARMACOLOGICAL SCIENCES,Vol. 133,No. 3,2017年03月
  • Interleukin-11 therapy for cardioprotection against acute myocardial infarction,Fujio Yasushi,Maeda Makiko,Daimon Takashi,Nakatani Daisaku,Sugioka Kinichi,Iwata Shinichi,Sawa Yoshiki,Asakura Masanori,Izumi Yasukatsu,Yoshiyama Minoru,JOURNAL OF PHARMACOLOGICAL SCIENCES,Vol. 133,No. 3,2017年03月
  • Caveolae-specific activation loop between CaMKII and L-type Ca<sup>2+</sup> channel aggravates cardiac hypertrophy in α<sub>1</sub>-adrenergic stimulation.,Tonegawa K,Otsuka W,Kumagai S,Matsunami S,Hayamizu N,Tanaka S,Moriwaki K,Obana M,Maeda M,Asahi M,Kiyonari H,Fujio Y,Nakayama H,American journal of physiology. Heart and circulatory physiology,Vol. 312,No. 3,p. H501-H514,2017年03月,研究論文(学術雑誌)
  • Myeloid Cell-Specific Runx2 Deficiency Exacerbates Adverse Cardiac Remodeling After Myocardial Infarction,Moe Ashizuka,Shouhei Kumagai,Emiko Yanase,Masanori Obana,Makiko Maeda,Yasushi Sakata,Hiroyuki Nakayama,Yasushi Fujio,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 134,2016年11月
  • Heterozygous Ablation of ROR gamma t Gene Deteriorates Adverse Cardiac Remodeling After Myocardial Infarction,Daichi Enomoto,Masanori Obana,Kotaro Matsumoto,Yasushi Sakata,Makiko Maeda,Hiroyuki Nakayama,Yasushi Fujio,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 134,2016年11月
  • Fibroblast-specific Beta-adrenergic Receptor Signaling Regulates Cardiac Hypertrophy in Mice,Kota Tonegawa,Shota Tanaka,Misato Takahashi,Shota Fuchigami,Masanori Obana,Makiko Maeda,Yasushi Sakata,Yasushi Fujio,Hiroyuki Nakayama,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 134,2016年11月
  • Adult Mammalian Hearts Restore Intrinsic Regenerative Capacity Through Signal Transducer and Activation of Transcription 3 in the Resolution Phase of Myocarditis,Akimitsu Miyawaki,Masanori Obana,Yusuke Mitsuhara,Aya Orimoto,Yusuke Nakayasu,Tomomi Yamashita,So-ichiro Fukada,Makiko Maeda,Yasushi Sakata,Hiroyuki Nakayama,Yasushi Fujio,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 134,2016年11月
  • Four cases of investigational therapy with interleukin-11 against acute myocardial infarction.,Masashi Nakagawa,Yasuko Owada,Yasukatsu Izumi,Shinichi Nonin,Kenichi Sugioka,Daisaku Nakatani,Shinichi Iwata,Kazuki Mizutani,Satoshi Nishimura,Asahiro Ito,Suwako Fujita,Takashi Daimon,Yoshiki Sawa,Masanori Asakura,Makiko Maeda,Yasushi Fujio,Minoru Yoshiyama,Heart and vessels,Vol. 31,No. 9,p. 1574-8,2016年09月
  • Moesin is activated in cardiomyocytes in experimental autoimmune myocarditis and mediates cytoskeletal reorganization with protrusion formation,Akimitsu Miyawaki,Yusuke Mitsuhara,Aya Orimoto,Yusuke Nakayasu,Shin-ichi Tsunoda,Masanori Obana,Makiko Maeda,Hiroyuki Nakayama,Yasuo Yoshioka,Yasuo Tsutsumi,Yasushi Fujio,AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY,AMER PHYSIOLOGICAL SOC,Vol. 311,No. 2,p. H476-H486,2016年08月,研究論文(学術雑誌)
  • Adult cardiomyocytes restore intrinsic regenerative capacity through STAT3 activation in the inflamed murine heart,Miyawaki Akimitsu,Takaya Tamaki,Mitsuhara Yusuke,Yamashita Tomomi,Obana Masanori,Maeda Makiko,Nakayama Hiroyuki,Fujio Yasushi,JOURNAL OF PHARMACOLOGICAL SCIENCES,Vol. 130,No. 3,2016年03月
  • Elucidation of underlying mechanism of 2-APB against ROS-induced CM death,Ishida Akiko,Morihara Hirofumi,Kawakatsu Ikki,Tsuchiyama Daisuke,Kubo Mikiko,Obana Masanori,Maeda Makiko,Fujio Yasushi,Nakayama Hiroyuki,JOURNAL OF PHARMACOLOGICAL SCIENCES,Vol. 130,No. 3,2016年03月
  • Myeloid cell-derived LRG attenuates adverse cardiac remodelling after myocardial infarction,Shohei Kumagai,Hiroyuki Nakayama,Minoru Fujimoto,Hiromi Honda,Satoshi Serada,Hatsue Ishibashi-Ueda,Atsushi Kasai,Masanori Obana,Yasushi Sakata,Yoshiki Sawa,Yasushi Fujio,Tetsuji Naka,CARDIOVASCULAR RESEARCH,OXFORD UNIV PRESS,Vol. 109,No. 2,p. 272-282,2016年02月,研究論文(学術雑誌)
  • Adrenergic Receptors beta 2 and beta 3 Transduce Differential Signals in Cardiac Fibroblasts,Kota Tonegawa,Hiroyuki Nakayama,Hiromi Igarashi,Sachi Matsunami,Nao Hayamizu,Masanori Obana,Makiko Maeda,Yasushi Fujio,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 132,2015年11月
  • Blockade of NKG2D/NKG2D Ligands Interaction Attenuated Cardiac Remodeling After Myocardial Infarction,Kotaro Matsumoto,Masanori Obana,Rina Hashizume,Yukari Yokoyama,Shigeru Miyagawa,Tomomi Mohri,Makiko Maeda,Hiroyuki Nakayama,Yoshiki Sawa,Yasushi Fujio,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 132,2015年11月
  • Interleukin-27 induces the endothelial differentiation in Sca-1+cardiac resident stem cells,Tomohiro Tanaka,Masanori Obana,Tomomi Mohri,Masaki Ebara,Yuta Otani,Makiko Maeda,Yasushi Fujio,CYTOKINE,ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD,Vol. 75,No. 2,p. 365-372,2015年10月,研究論文(学術雑誌)
  • Cardiac-specific ablation of the STAT3 gene in the subacute phase of myocardial infarction exacerbated cardiac remodeling,Daichi Enomoto,Masanori Obana,Akimitsu Miyawaki,Makiko Maeda,Hiroyuki Nakayama,Yasushi Fujio,AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY,AMER PHYSIOLOGICAL SOC,Vol. 309,No. 3,p. H471-H480,2015年08月,研究論文(学術雑誌)
  • Elucidation of molecular mechanism of cardiomyocyte necrosis induced by reactive oxygen species,Tsuchiyama Daisuke,Nakayama Hiroyuki,Morihara Hirofumi,Ishida Akiko,Obana Masanori,Maeda Makiko,Fujio Yasushi,JOURNAL OF PHARMACOLOGICAL SCIENCES,Vol. 128,No. 3,2015年07月
  • Interleukin 27 induces endothelial differentiation in murine cardiac stem cells,Tanaka Tomohiro,Obana Masanori,Maeda Makiko,Nakayama Hiroyuki,Fujio Yasushi,JOURNAL OF PHARMACOLOGICAL SCIENCES,Vol. 128,No. 3,2015年07月
  • IL-27 negatively regulates murine experimental autoimmune myocarditis (EAM),Furutani Chika,Miyawaki Akimitsu,Otani Yuta,Obana Masanori,Maeda Makiko,Nakayama Hiroyuki,Fujio Yasushi,JOURNAL OF PHARMACOLOGICAL SCIENCES,Vol. 128,No. 3,2015年07月
  • The properties of cardiac Sca-1+resident stem cells are altered in response to myocardial inflammation,Matsuhara Yumi,Miyawaki Akimitsu,Ebara Masaki,Obana Masanori,Maeda Makiko,Nakayama Hiroyuki,Fujio Yasushi,JOURNAL OF PHARMACOLOGICAL SCIENCES,Vol. 128,No. 3,2015年07月
  • The Inhibition of N-Glycosylation of Glycoprotein 130 Molecule Abolishes STAT3 Activation by IL-6 Family Cytokines in Cultured Cardiac Myocytes,Reo Matsuo,Hirofumi Morihara,Tomomi Mohri,Shiho Murasawa,Kana Takewaki,Hiroyuki Nakayama,Makiko Maeda,Yasushi Fujio,PLOS ONE,PUBLIC LIBRARY SCIENCE,Vol. 9,No. 10,2014年10月,研究論文(学術雑誌)
  • Requirement of SLD5 for Early Embryogenesis,Tomomi Mohri,Masaya Ueno,Yumi Nagahama,Zhi-Yuan Gong,Masahide Asano,Hiroko Oshima,Masanobu Oshima,Yasushi Fujio,Nobuyuki Takakura,PLOS ONE,PUBLIC LIBRARY SCIENCE,Vol. 8,No. 11,2013年11月,研究論文(学術雑誌)
  • Polymorphisms of CYP2D6 Gene and Gefitinib-Induced Hepatotoxicity,Takayuki Takimoto,Takashi Kijima,Yasushi Otani,Shinpei Nonen,Yoshinobu Namba,Masahide Mori,Soichiro Yokota,Seigo Minami,Kiyoshi Komuta,Junji Uchida,Fumio Imamura,Mitsugi Furukawa,Naotoshi Tsuruta,Yasushi Fujio,Junichi Azuma,Isao Tachibana,Atsushi Kumanogoh,CLINICAL LUNG CANCER,CIG MEDIA GROUP, LP,Vol. 14,No. 5,p. 502-507,2013年09月,研究論文(学術雑誌)
  • Cathelicidin antimicrobial peptide inhibits fibroblast migration via P2X7 receptor signaling,Shohei Kumagai,Kazuki Matsui,Haruyo Kawaguchi,Tomomi Yamashita,Tomomi Mohri,Yasushi Fujio,Hiroyuki Nakayama,Biochemical and Biophysical Research Communications,Vol. 437,No. 4,p. 609-614,2013年08月09日,研究論文(学術雑誌)
  • Genetic polymorphisms of CYP17A1 in steroidogenesis pathway are associated with risk of progression to castration-resistant prostate cancer in Japanese men receiving androgen deprivation therapy,Takeshi Yamada,Masashi Nakayama,Tomohito Shimizu,Shinpei Nonen,Yasutomo Nakai,Kazuo Nishimura,Yasushi Fujio,Akihiko Okuyama,Junichi Azuma,Norio Nonomura,INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY,SPRINGER JAPAN KK,Vol. 18,No. 4,p. 711-717,2013年08月,研究論文(学術雑誌)
  • NAT2 genotype guided regimen reduces isoniazid-induced liver injury and early treatment failure in the 6-month four-drug standard treatment of tuberculosis: A randomized controlled trial for pharmacogenetics-based therapy,Junichi Azuma,Masako Ohno,Ryuji Kubota,Soichiro Yokota,Takayuki Nagai,Kazunari Tsuyuguchi,Yasuhisa Okuda,Tetsuya Takashima,Sayaka Kamimura,Yasushi Fujio,Ichiro Kawase,EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY,SPRINGER HEIDELBERG,Vol. 69,No. 5,p. 1091-1101,2013年05月,研究論文(学術雑誌)
  • Minimal dose for effective clinical outcome and predictive factors for responsiveness to carvedilol: Japanese chronic heart failure (J-CHF) study,Hiroshi Okamoto,Masatsugu Hori,Masunori Matsuzaki,Hiroyuki Tsutsui,Tsutomu Yamazaki,Ryozo Nagai,Tsutomu Yoshikawa,Yasushi Fujio,Shinpei Nonen,Junichi Azuma,Tohru Izumi,Yasuo Ohashi,Akira Kitabatake,INTERNATIONAL JOURNAL OF CARDIOLOGY,ELSEVIER IRELAND LTD,Vol. 164,No. 2,p. 238-244,2013年04月,研究論文(学術雑誌)
  • Therapeutic administration of IL-11 exhibits the postconditioning effects against ischemia-reperfusion injury via STAT3 in the heart,Masanori Obana,Kaori Miyamoto,Shiho Murasawa,Tomohiko Iwakura,Akiko Hayama,Tomomi Yamashita,Momoko Shiragaki,Shohei Kumagai,Akimitsu Miyawaki,Kana Takewaki,Goro Matsumiya,Makiko Maeda,Minoru Yoshiyama,Hiroyuki Nakayama,Yasushi Fujio,AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY,AMER PHYSIOLOGICAL SOC,Vol. 303,No. 5,p. H569-H577,2012年09月,研究論文(学術雑誌)
  • Endothelial Gab1 Deletion Accelerates Angiotensin II-Dependent Vascular Inflammation and Atherosclerosis in Apolipoprotein E Knockout Mice,Kaori Higuchi,Yoshikazu Nakaoka,Wataru Shioyama,Yoh Arita,Takahiro Hashimoto,Taku Yasui,Kuniyasu Ikeoka,Tadashi Kuroda,Takashi Minami,Keigo Nishida,Yasushi Fujio,Keiko Yamauchi-Takihara,Mikiyasu Shirai,Naoki Mochizuki,Issei Komuro,CIRCULATION JOURNAL,JAPANESE CIRCULATION SOC,Vol. 76,No. 8,p. 2031-2040,2012年08月,研究論文(学術雑誌)
  • Interleukin-11 Exhibits the Post-conditioning Effects against Ischemia Reperfusion injury via Cardiac Signal Transducer and Activator of Transcription 3,Kaori Miyamoto,Masanori Obana,Makiko Maeda,Hiroyuki Nakayama,Yasushi Fujio,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 118,p. 86P-86P,2012年
  • Interleukin-11 Attenuates Infarct Size And Improves Ventricular Function In a Canine Heart Model Of Ischemia/Reperfusion Injury,Makiko Maeda,Koji Takeda,Goro Matsumiya,Junichi Azuma,Yasushi Fujio,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 118,p. 244P-244P,2012年
  • Glycoprotein 130 Cytokine Signal as a Therapeutic Target Against Cardiovascular Diseases,Yasushi Fujio,Makiko Maeda,Tomomi Mohri,Masanori Obana,Tomohiko Iwakura,Akiko Hayama,Tomomi Yamashita,Hiroyuki Nakayama,Junichi Azuma,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 117,No. 4,p. 213-222,2011年12月
  • [Genetic analysis for nicotine dependence].,Maeda M,Fujio Y,Azuma J,Nihon rinsho. Japanese journal of clinical medicine,Vol. 69,No. 10,p. 1887-1890,2011年10月
  • Association between osteopontin promoter variants and diastolic dysfunction in hypertensive heart in the Japanese population,Hiroyuki Nakayama,Hiromi Nagai,Kyotaka Matsumoto,Ryosuke Oguro,Ken Sugimoto,Kei Kamide,Mitsuru Ohishi,Tomohiro Katsuya,Hiroshi Okamoto,Makiko Maeda,Kazuo Komamura,Junichi Azuma,Hiromi Rakugi,Yasushi Fujio,HYPERTENSION RESEARCH,NATURE PUBLISHING GROUP,Vol. 34,No. 10,p. 1141-1146,2011年10月,研究論文(学術雑誌)
  • IL-6-mediated Th17 differentiation through ROR gamma t is essential for the initiation of experimental autoimmune myocarditis,Tomomi Yamashita,Tomohiko Iwakura,Kazuki Matsui,Haruyo Kawaguchi,Masanori Obana,Akiko Hayama,Makiko Maeda,Yasukatsu Izumi,Issei Komuro,Yoshiyuki Ohsugi,Minoru Fujimoto,Tetsuji Naka,Tadamitsu Kishimoto,Hiroyuki Nakayama,Yasushi Fujio,CARDIOVASCULAR RESEARCH,OXFORD UNIV PRESS,Vol. 91,No. 4,p. 640-648,2011年09月,研究論文(学術雑誌)
  • STAT3/Pim-1 signaling pathway plays a crucial role in endothelial differentiation of cardiac resident Sca-1+cells both in vitro and in vivo,Tomohiko Iwakura,Tomomi Mohri,Tatsuto Hamatani,Masanori Obana,Tomomi Yamashita,Makiko Maeda,Naoto Katakami,Hideaki Kaneto,Toru Oka,Issei Komuro,Junichi Azuma,Hiroyuki Nakayama,Yasushi Fujio,JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY,ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD,Vol. 51,No. 2,p. 207-214,2011年08月,研究論文(学術雑誌)
  • Safe and Successful Treatment With Erlotinib After Gefitinib-Induced Hepatotoxicity: Difference in Metabolism As a Possible Mechanism,Takashi Kijima,Tomohito Shimizu,Shinpei Nonen,Mitsugi Furukawa,Yasushi Otani,Toshiyuki Minami,Ryo Takahashi,Haruhiko Hirata,Izumi Nagatomo,Yoshito Takeda,Hiroshi Kida,Sho Goya,Yasushi Fujio,Junichi Azuma,Isao Tachibana,Ichiro Kawase,JOURNAL OF CLINICAL ONCOLOGY,AMER SOC CLINICAL ONCOLOGY,Vol. 29,No. 19,p. E588-E590,2011年07月,研究論文(学術雑誌)
  • Docking Protein Gab1 Is an Essential Component of Postnatal Angiogenesis After Ischemia via HGF/c-Met Signaling,Wataru Shioyama,Yoshikazu Nakaoka,Kaori Higuchi,Takashi Minami,Yoshiaki Taniyama,Keigo Nishida,Hiroyasu Kidoya,Takashi Sonobe,Hisamichi Naito,Yoh Arita,Takahiro Hashimoto,Tadashi Kuroda,Yasushi Fujio,Mikiyasu Shirai,Nobuyuki Takakura,Ryuichi Morishita,Keiko Yamauchi-Takihara,Tatsuhiko Kodama,Toshio Hirano,Naoki Mochizuki,Issei Komuro,CIRCULATION RESEARCH,LIPPINCOTT WILLIAMS & WILKINS,Vol. 108,No. 6,p. 664-U299,2011年03月,研究論文(学術雑誌)
  • Interleukin-11 exhibits the post-conditioning effects against ischemia reperfusion injury through cardiac STAT3 activation,Masanori Obana,Kaori Miyamoto,Tomohiko Iwakura,Akiko Hayama,Tomomi Yamashita,Shiho Murasawa,Momoko Shiragaki,Makiko Maeda,Junichi Azuma,Hiroyuki Nakayama,Yasushi Fujio,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 115,p. 110P-110P,2011年
  • Interleukin-6 family cytokines induce endothelial cell differentiation of cardiac Sca-1+cells via STAT3/Pim-1 signaling pathway,Tomohiko Iwakura,Tomomi Mohri,Tatsuto Hamatani,Tomomi Yamashita,Masanori Obana,Akiko Hayama,Kazuki Matsui,Makiko Maeda,Junichi Azuma,Hiroyuki Nakayama,Yasushi Fujio,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 115,p. 96P-96P,2011年
  • Cathelicidin antimicrobial peptide (CAMP) is induced in autoimmune myocarditis and reduces the motility of cardiac fibroblasts,Kazuki Matsui,Tomomi Yamashita,Haruyo Kawaguchi,Tomohiko Iwakura,Masanori Obana,Akiko Hayama,Shiho Murasawa,Kohei Katayama,Momoko Shiragaki,Makiko Maeda,Junichi Azuma,Hiroyuki Nakayama,Yasushi Fujio,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 115,p. 110P-110P,2011年
  • Cigarette Smoke Extract Induces CYP2B6 through Constitutive Androstane Receptor in Hepatocytes,Ikumi Washio,Makiko Maeda,Chika Sugiura,Ryota Shiga,Mitsuhiro Yoshida,Shinpei Nonen,Yasushi Fujio,Junichi Azuma,DRUG METABOLISM AND DISPOSITION,AMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS,Vol. 39,No. 1,p. 1-3,2011年01月,研究論文(学術雑誌)
  • RGS2 determines the preventive effects of ARBs against vascular remodeling: toward personalized medicine of anti-hypertensive therapy with ARBs,Yasushi Fujio,HYPERTENSION RESEARCH,NATURE PUBLISHING GROUP,Vol. 33,No. 12,p. 1221-1222,2010年12月
  • Pim-1 Kinase is Required for Endothelial Differentiation of Cardiac Stem Cells via STAT3 Signaling Pathway,Tomohiko Iwakura,Tomomi Mohri,Tatsuto Hamatani,Tomomi Yamashita,Masanori Obana,Akiko Hayama,Makiko Maeda,Hiroyuki Nakayama,Issei Komuro,Junichi Azuma,Yasushi Fujio,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 122,No. 21,2010年11月
  • The Gene Polymorphisms of CYP2A6 and the Nicotinic Acetylcholine Receptor alpha 4 Subunit Influence Nicotine Dependence, Which is One of the Cardiovascular Risk Factors, in Japanese Smokers,Makiko Maeda,Chieko N. Taniguchi,Masanobu Funamoto,Genta Miura,Tomoko Kubota,Chika Sugiura,Ryota Shiga,Shipei Nonen,Yasushi Fujio,Junichi Azuma,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 122,No. 21,2010年11月
  • SHP2 mediates gp130-dependent cardiomyocyte hypertrophy via negative regulation of skeletal alpha-actin gene,Yoshikazu Nakaoka,Wataru Shioyama,Satoshi Kunimoto,Yoh Arita,Kaori Higuchi,Kaori Yamamoto,Yasushi Fujio,Keigo Nishida,Tadashi Kuroda,Hisao Hirota,Keiko Yamauchi-Takihara,Toshio Hirano,Issei Komuro,Naoki Mochizuki,JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY,ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD,Vol. 49,No. 2,p. 157-164,2010年08月,研究論文(学術雑誌)
  • Therapeutic Activation of Signal Transducer and Activator of Transcription 3 by Interleukin-11 Ameliorates Cardiac Fibrosis After Myocardial Infarction,Masanori Obana,Makiko Maeda,Koji Takeda,Akiko Hayama,Tomomi Mohri,Tomomi Yamashita,Yoshikazu Nakaoka,Issei Komuro,Kiyoshi Takeda,Goro Matsumiya,Junichi Azuma,Yasushi Fujio,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 121,No. 5,p. 684-U121,2010年02月,研究論文(学術雑誌)
  • Interleukin-11 ameliorates cardiac remodeling after myocardial infarction through STAT3,Masanori Obana,Makiko Maeda,Junichi Azuma,Yasushi Fujio,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 112,p. 74P-74P,2010年
  • Interleukin-11 Attenuates Infarct Size and Improves Ventricular Function in a Canine Heart Model of Ischemia/Reperfusion Injury,Koji Takeda,Goro Matsumiya,Shigeru Miyagawa,Makiko Maeda,Yasushi Fujio,Yoshiki Sawa,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 120,No. 18,p. S737-S737,2009年11月
  • Influence of clinical and genetic factors on warfarin dose requirements among Japanese patients,Masako Ohno,Akiko Yamamoto,Ayumu Ono,Genta Miura,Masanobu Funamoto,Yasuhiko Takemoto,Kinya Otsu,Yasushi Kouno,Tomoko Tanabe,Yuiko Masunaga,Shinpei Nonen,Yasushi Fujio,Junichi Azuma,EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY,SPRINGER,Vol. 65,No. 11,p. 1097-1103,2009年11月,研究論文(学術雑誌)
  • Clinical significance of plasma endothelin-1 level after bosentan administration in pulmonary arterial hypertension,Yoshimune Hiramoto,Wataru Shioyama,Kaori Higuchi,Yoh Arita,Tadashi Kuroda,Yasushi Sakata,Yoshikazu Nakaoka,Yasushi Fujio,Keiko Yamauchi-Takihara,JOURNAL OF CARDIOLOGY,ELSEVIER IRELAND LTD,Vol. 53,No. 3,p. 374-380,2009年06月,研究論文(学術雑誌)
  • Signals Through Glycoprotein 130 Regulate the Endothelial Differentiation of Cardiac Stem Cells,Tomomi Mohri,Yasushi Fujio,Masanori Obana,Tomohiko Iwakura,Koichi Matsuda,Makiko Maeda,Junichi Azuma,ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY,LIPPINCOTT WILLIAMS & WILKINS,Vol. 29,No. 5,p. 754-760,2009年05月,研究論文(学術雑誌)
  • Analyses on the in vivo transdifferentiation of cardiac stem cells into endothelial cell lineage in post-infarct myocardium,Koichi Matsuda,Yasushi Fujio,Tomomi Mohri,Masanori Obana,Tomohiko Iwakura,Tomomi Yamashita,Akiko Hayama,Makiko Maeda,Junichi Azuma,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 109,p. 118P-118P,2009年
  • Th17 cells are induced in chronic inflammation after myocardial infarction,Akiko Hayama,Yasushi Fujio,Masanori Obana,Tomomi Mohri,Tomomi Yamashita,Tomohiko Iwakura,Makiko Maeda,Junichi Azuma,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 109,p. 118P-118P,2009年
  • IL-6 family cytokines induce IL-10 in cardiac myocytes via STAT3 and ERK1/2 signaling pathway,Tomohiko Iwakura,Yasushi Fujio,Makiko Maeda,Tomomi Mohri,Masanori Obana,Koichi Matsuda,Tomomi Yamashita,Akiko Hayama,Junichi Azuma,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 109,p. 62P-62P,2009年
  • The infiltration of Th17 cells into myocardium is associated with severity of the inflammation in experimental autoimmune myocarditis (EAM),Tomomi Yamashita,Yasushi Fujio,Akiko Hayama,Kouichi Matsuda,Masanori Obana,Tomohiko Iwakura,Tornomi Mohri,Makiko Maeda,Junichi Azuma,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 109,p. 117P-117P,2009年
  • Involvement of Transcriptional Factor TonEBP in the Regulation of the Taurine Transporter in the Cardiomyocyte,Takashi Ito,Yasushi Fujio,Stephen W. Schaffer,Junichi Azuma,Taurine 7,SPRINGER,Vol. 643,p. 523-532,2009年,研究論文(学術雑誌)
  • Beneficial Effect of Taurine Treatment Against Doxorubicin-Induced Cardiotoxicity in Mice,Takashi Ito,Satoko Muraoka,Kyoko Takahashi,Yasushi Fujio,Stephen W. Schaffer,Junichi Azuma,Taurine 7,SPRINGER,Vol. 643,p. 65-74,2009年,研究論文(学術雑誌)
  • Pharmacokinetics/genotype associations for major cytochrome P450 enzymes in native and first- and third-generation Japanese populations: Comparison with Korean, Chinese, and Caucasian populations,S. P. Myrand,K. Sekiguchi,M. Z. Man,X. Lin,R-Y Tzeng,C-H Teng,B. Hee,M. Garrett,H. Kikkawa,C-Y Lin,S. M. Eddy,J. Dostalik,J. Mount,J. Azuma,Y. Fujio,I-J Jang,S-G Shin,M. R. Bleavins,J. A. Williams,J. D. Paulauskis,K. D. Wilner,CLINICAL PHARMACOLOGY & THERAPEUTICS,NATURE PUBLISHING GROUP,Vol. 84,No. 3,p. 347-361,2008年09月,研究論文(学術雑誌)
  • Interaction of scaffolding adaptor protein Gab1 with tyrosine phosphatase SHP2 negatively regulates IGF-I-dependent myogenic differentiation via the ERK1/2 signaling pathway,Tatsuya Koyama,Yoshikazu Nakaoka,Yasushi Fujio,Hisao Hirota,Keigo Nishida,Shoko Sugiyama,Kitaro Okamoto,Keiko Yamauchi-Takihara,Michihiro Yoshimura,Seibu Mochizuki,Masatsugu Hori,Toshio Hiran,Naoki Mochizuki,JOURNAL OF BIOLOGICAL CHEMISTRY,AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC,Vol. 283,No. 35,p. 24234-24244,2008年08月,研究論文(学術雑誌)
  • Atrogin-1 ubiquitin ligase is upregulated by doxorubicin via p38-MAP kinase in cardiac myocytes,Yasuhiro Yamamoto,Yuki Hoshino,Takashi Ito,Tetsuro Nariai,Tomomi Mohri,Masanori Obana,Nozomi Hayata,Yoriko Uozumi,Makiko Maeda,Yasushi Fujio,Junichi Azuma,CARDIOVASCULAR RESEARCH,OXFORD UNIV PRESS,Vol. 79,No. 1,p. 89-96,2008年07月,研究論文(学術雑誌)
  • Taurine depletion caused by knocking out the taurine transporter gene leads to cardiomyopathy with cardiac atrophy,Takashi Ito,Yasushi Kimura,Yoriko Uozumi,Mika Takai,Satoko Muraoka,Takahisa Matsuda,Kei Ueki,Minoru Yoshiyama,Masahito Ikawa,Masara Okabe,Stephen W. Schaffer,Yasushi Fujio,Junichi Azuma,JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY,ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD,Vol. 44,No. 5,p. 927-937,2008年05月,研究論文(学術雑誌)
  • Connective tissue growth factor induces cardiac hypertrophy through Akt signaling,Nozomi Hayata,Yasushi Fujio,Yasuhiro Yamamoto,Tomohiko Iwakura,Masanori Obana,Mika Takai,Tomomi Mohri,Shinpei Nonen,Makiko Maeda,Junichi Azuma,BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,ACADEMIC PRESS INC ELSEVIER SCIENCE,Vol. 370,No. 2,p. 274-278,2008年05月,研究論文(学術雑誌)
  • MTHFR gene polymorphism is susceptible to diabetic retinopathy but not to diabetic nephropathy in Japanese type 2 diabetic patients,Makiko Maeda,Isamu Yamamoto,Masakatsu Fukuda,Takashi Motomura,Mari Nishida,Shinpei Nonen,Soji Kasayama,Yasushi Fujio,Junichi Azuma,JOURNAL OF DIABETES AND ITS COMPLICATIONS,ELSEVIER SCIENCE INC,Vol. 22,No. 2,p. 119-125,2008年03月,研究論文(学術雑誌)
  • Polymorphisms of norepinephrine transporter and adrenergic receptor alpha(1D) are associated with the response to beta-blockers in dilated cardiomyopathy,S. Nonen,H. Okamoto,Y. Fujio,Y. Takemoto,M. Yoshiyama,T. Hamaguchi,Y. Matsui,J. Yoshikawa,A. Kitabatake,J. Azuma,PHARMACOGENOMICS JOURNAL,NATURE PUBLISHING GROUP,Vol. 8,No. 1,p. 78-84,2008年02月,研究論文(学術雑誌)
  • Adrenergic beta(1) receptor polymorphism (Ser49Gly) is associated with obesity in type II diabetic patients,Shinpei Nonen,Isamu Yamamoto,Jianmin Liu,Makiko Maeda,Takashi Motomura,Tsuyoshi Igarashi,Yasushi Fujio,Junichi Azuma,BIOLOGICAL & PHARMACEUTICAL BULLETIN,PHARMACEUTICAL SOC JAPAN,Vol. 31,No. 2,p. 295-298,2008年02月,研究論文(学術雑誌)
  • Signals through gp130 mediate the endothelial differentiation in cardiac Sca-1+stem cells,Tomomi Mohri,Yasushi Fujio,Tomohiko Iwakura,Masanori Obana,Koichi Matsuda,Makiko Maeda,Takashi Ito,Yasuhiro Yamamoto,Nozomi Hayata,Akiko Hayama,Tomomi Yamashita,Junichi Azuma,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 106,p. 58P-58P,2008年
  • Skeletal muscle-derived Sca-1+stem cells are differentiated into endothelial cells by Leukemia inhibitory factor,Tomohiko Iwakura,Yasushi Fujio,Makiko Maeda,Tomomi Mohri,Koichi Matsuda,Tomomi Yamashita,Takashi Ito,Yasuhiro Yamamoto,Masanori Obana,Nozomi Hayata,Mika Takai,Akiko Hayama,Yukako Ueno,Haruaki Nobori,Kouhei Yamashita,Junichi Azuma,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 106,p. 99P-99P,2008年
  • Interleukin (IL)-11 ameliorates cardiac remodeling with angiogenic and anti-inflammatory effects in murine myocardial infarction model,Masanori Obana,Makiko Maeda,Yasubito Yamamoto,Takashi Ito,Tomomi Mohri,Tomohiko Iwakura,Nozomi Hayata,Mika Takai,Akiko Hayama,Koichi Matsuda,Kouhei Yamashita,Yasushi Fujio,Juriichi Azuma,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 106,p. 112P-112P,2008年
  • Connective tissue growth factor mediates hypertrophic signals through its C-terminal domain in cultured cardiac myocytes,Nozomi Hayata,Yasushi Fujio,Takashi Ito,Tomomi Mohri,Yasuhiro Yamamoto,Masanori Obana,Tomohiko Iwakura,Mika Takai,Koichi Matsuda,Yukako Ueno,Makiko Maeda,Shinpei Nonen,Junichi Azuma,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 106,p. 120P-120P,2008年
  • Interleukin-11 prevents cardiac remodeling after myocardial infarction with Neovascularization in murine model,Masanori Obana,Makiko Maeda,Yasuhiro Yamamoto,Takashi Ito,Tomomi Mohn,Tomohiko Iwakura,Nozomi Hayata,Mika Takai,Akiko Hayama,Koichi Matsuda,Kouhei Yamashita,Yasushi Fujio,Junichi Azuma,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 116,No. 16,p. 262-262,2007年10月
  • Signals through glycoprotein 130 promote the endothelial differentiation of cardiac Sca(-1)+ cells,Tomomi Mohri,Yasushi Fujio,Tomohiko Iwakura,Masanori Obana,Koichi Matsuda,Makiko Maeda,Takashi Ito,Yasuhiro Yamamoto,Nozomi Hayata,Junichi Azuma,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 116,No. 16,p. 48-48,2007年10月
  • Regulation of cytochrome P450 2E1 under hypertonic environment through TonEBP in human hepatocytes,Takashi Ito,Koko Asakura,Katsuhiko Tougou,Tsuyoshi Fukuda,Ryuji Kubota,Shinpei Nonen,Yasushi Fujio,Junichi Azuma,MOLECULAR PHARMACOLOGY,AMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS,Vol. 72,No. 1,p. 173-181,2007年07月,研究論文(学術雑誌)
  • Gab family proteins are essential for postnatal maintenance of cardiac function via neuregulin-1/ErbB signaling,Yoshikazu Nakaoka,Keigo Nishida,Masahiro Narimatsu,Atsunori Kamiya,Takashi Minami,Hirofumi Sawa,Katsuya Okawa,Yasushi Fujio,Tatsuya Koyama,Makiko Maeda,Manami Sone,Satoru Yamasaki,Yuji Arai,Gou Young Koh,Tatsuhiko Kodama,Hisao Hirota,Kinya Otsu,Toshio Hirano,Naoki Mochizuki,JOURNAL OF CLINICAL INVESTIGATION,AMER SOC CLINICAL INVESTIGATION INC,Vol. 117,No. 7,p. 1771-1781,2007年07月,研究論文(学術雑誌)
  • Carbacyclin induces carnitine palmitoyltransferase-1 in cardiornyocytes via peroxisome proliferator-activated receptor (PPAR) delta independent of the IP receptor signaling pathway,Tadashi Kuroda,Hisao Hirota,Yasushi Fujio,Shoko Suglyama,Mitsuru Masaki,Yoshimune Hiramoto,Wataru Shioyama,Kitaro Okamoto,Masatsugu Horl,Keiko Yamauchi-Takihara,JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY,ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD,Vol. 43,No. 1,p. 54-62,2007年07月,研究論文(学術雑誌)
  • Identification of cardiac myocytes as the target of interleukin 11, a cardioprotective cytokine,Ryusuke Kimura,Makiko Maeda,Atsushi Arita,Yuichi Oshima,Masanori Obana,Takashi Ito,Yasuhiro Yamamoto,Tomorm Mohri,Tadamitsu Kishimoto,Ichiro Kawase,Yasushi Fujio,Junichi Azuma,CYTOKINE,ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD,Vol. 38,No. 2,p. 107-115,2007年05月,研究論文(学術雑誌)
  • Effect of bosentan on plasma endothelin-1 concentration in patients with pulmonary arterial hypertension,Yoshimune Hiramoto,Wataru Shioyama,Tadashi Kuroda,Mitsuru Masaki,Shoko Sugiyama,Kitaro Okamoto,Hisao Hirota,Yasushi Fujio,Masatsugu Hori,Keiko Yamauchi-Takihara,CIRCULATION JOURNAL,JAPANESE CIRCULATION SOCIETY,Vol. 71,No. 3,p. 367-369,2007年03月,研究論文(学術雑誌)
  • Rac1 activity is required for cardiac myocyte alignment in response to mechanical stress,Masako Yamane,Takahisa Matsuda,Takashi Ito,Yasushi Fujio,Kyoko Takahashi,Junichi Azuma,BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,ACADEMIC PRESS INC ELSEVIER SCIENCE,Vol. 353,No. 4,p. 1023-1027,2007年02月,研究論文(学術雑誌)
  • Interleukin (IL)-11 prevents ischemia/reperfusion (I/R) injury in hearts as a novel card ioprotective cytokine.,Makiko Maeda,Ryusuke Kimura,Atsushi Arita,Masanori Obana,Yasuhiro Yamamoto,Tomomi Mohri,Tomohiko Iwakura,Koichi Mastuda,Takashi Ito,Yasushi Kimura,Yuichi Oshima,Yasushi Fujio,Junichi Azuma,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 103,p. 117P-117P,2007年
  • Genetic polymorphism of bile acid CoA: Amino acid n-alpha cyltransferase in Japanese individuals,Katsuhiko Tougou,Tsuyoshi Fukuda,Takashi Ito,Hiroshi Yamazaki,Yasushi Fujio,Junichi Azuma,DRUG METABOLISM AND PHARMACOKINETICS,JAP SOC STUDY XENOBIOTICS,Vol. 22,No. 2,p. 125-128,2007年,研究論文(学術雑誌)
  • Degradation of NFAT5, a transcriptional regulator of osmotic stress-related genes, is a critical event for doxorubicin-induced cytotoxicity in cardiac myocytes,Takashi Ito,Yasushi Fujio,Kyoko Takahashi,Junichi Azuma,JOURNAL OF BIOLOGICAL CHEMISTRY,AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC,Vol. 282,No. 2,p. 1152-1160,2007年01月,研究論文(学術雑誌)
  • MTHFR gene polymorphism and diabetic retinopathy,Makiko Maeda,Yasushi Fujio,Junichi Azuma,Current Diabetes Reviews,Vol. 2,No. 4,p. 467-476,2006年11月
  • Warfarin dose requirement for patients with both VKORCI 3673A/A and CYP2C9*3/*3 genotypes,Tsuyoshi Fukuda,Tomoko Tanabe,Masako Ohno,Katsuhiko Tougou,Yasushi Fujio,Junichi Azuma,Isamu Yamamoto,Akira Takeda,CLINICAL PHARMACOLOGY & THERAPEUTICS,MOSBY, INC,Vol. 80,No. 5,p. 553-554,2006年11月
  • Interleukin (IL)-11 prevents ischemia/reperfusion injury in hearts as a novel cardioprotective cytokine,Makiko Maeda,Yasushi Fujio,Ryusuke Kimura,Atsushi Arita,Takashi Itoh,Yasuhiro Yamamoto,Tomomi Mohri,Yuichi Oshima,Junich Azuma,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 114,No. 18,p. 208-208,2006年10月
  • Atrogin-1 ubiquitin ligase is upregulated by doxorubicin, leading to muscle atrophy in cardiac myocytes,Yasushi Fujio,Yuki Hoshino-Nariai,Yasuhiro Yamamoto,Takashi Ito,Yoriko Uozumi,Tomomi Mohri,Masanori Obana,Tetsurou Nariai,Yasushi Kimura,Makiko Maeda,Junichi Azuma,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 114,No. 18,p. 332-332,2006年10月
  • Cardiac sca-1+cells were differentiated into endothelial cells by leukemia inhibitory factor, a paracrine cytokine,Tomomi Mohh,Yasushi Fujio,Makiko Maeda,Takashi Ito,Tomohiko Iwakura,Yoriko Uozumi,Yasuhiro Yamamoto,Junichi Azuma,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 114,No. 18,p. 120-120,2006年10月
  • Antisense to cyclin D1 inhibits vascular endothelial growth factor-stimulated growth of vascular endothelial cells: Implication of tumor vascularization,Masayoshi Yasui,Hirofumi Yamamoto,Chew Yee Ngan,Bazarragchaa Damdinsuren,Yurika Sugita,Hiroki Fukunaga,Jinyu Gu,Makiko Maeda,Ichiro Takemasa,Masataka Ikeda,Yasushi Fujio,Mitsugu Sekimoto,Nariaki Matsuura,I. Bernard Weinstein,Morito Monden,CLINICAL CANCER RESEARCH,AMER ASSOC CANCER RESEARCH,Vol. 12,No. 15,p. 4720-4729,2006年08月,研究論文(学術雑誌)
  • Degradation of transcription factor NFAT5 is induced by doxorubicin exposure in cultured cardiomyocytes,Ito Takashi,Uozumi Yoriko,Maeda Makiko,Yamamoto Yasuhiro,Mohri Tomomi,Fujio Yasushi,Azuma Junichi,ACTA PHARMACOLOGICA SINICA,BLACKWELL PUBLISHING,Vol. 27,p. 140-140,2006年07月
  • Leukemia inhibitory factor induces endothelial differentiation in cardiac Sca-1+stem cells,Mohri Tomomi,Fujio Yasushi,Maeda Makiko,Ito Takashi,Iwakura Tomo-hiko,Oshima Yuichi,Uozumi Yoriko,Yamamoto Yasuhiro,Azuma Junichi,ACTA PHARMACOLOGICA SINICA,BLACKWELL PUBLISHING,Vol. 27,p. 183-183,2006年07月
  • N-cadherin signals through Rac1 determine the localization of connexin 43 in cardiac myocytes,T Matsuda,Y Fujio,T Nariai,T Ito,M Yamane,T Takatani,K Takahashi,J Azuma,JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY,ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD,Vol. 40,No. 4,p. 495-502,2006年04月,研究論文(学術雑誌)
  • Myogenic differentiation induces taurine transporter in association with taurine-mediated cytoprotection in skeletal muscles,Y Uozumi,T Ito,Y Hoshino,T Mohri,M Maeda,K Takahashi,Y Fujio,J Azuma,BIOCHEMICAL JOURNAL,PORTLAND PRESS LTD,Vol. 394,p. 699-706,2006年03月,研究論文(学術雑誌)
  • Leukemia inhibitory factor induces endothelial differentiation in cardiac stem cells,T Mohri,Y Fujio,M Maeda,T Ito,T Iwakura,Y Oshima,Y Uozumi,M Segawa,H Yamamoto,T Kishimoto,J Azuma,JOURNAL OF BIOLOGICAL CHEMISTRY,AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC,Vol. 281,No. 10,p. 6442-6447,2006年03月,研究論文(学術雑誌)
  • CYP2A6 polymorphisms are associated with nicotine dependence and influence withdrawal symptoms in smoking cessation,T Kubota,C Nakajima-Taniguchi,T Fukuda,M Funamoto,M Maeda,E Tange,R Ueki,K Kawashima,H Hara,Y Fujio,J Azuma,PHARMACOGENOMICS JOURNAL,NATURE PUBLISHING GROUP,Vol. 6,No. 2,p. 115-119,2006年03月,研究論文(学術雑誌)
  • TauT gene expression is regulated by TonEBP and plays a role in cell survival,Takashi Ito,Yasushi Fujio,Yoriko Uozumi,Takahisa Matsuda,Makiko Maeda,Kyoko Takahashi,Junichi Azuma,TAURINE 6,SPRINGER-VERLAG BERLIN,Vol. 583,p. 91-98,2006年,研究論文(学術雑誌)
  • Myogenic induction of taurine transporter prevents dexamethasone-induced muscle atrophy,Yoriko Uozumi,Takashi Ito,Kyoko Takahashi,Takahisa Matsuda,Tomomi Mohri,Yasushi Kimura,Yasushi Fujio,Junichi Azuma,TAURINE 6,SPRINGER-VERLAG BERLIN,Vol. 583,p. 265-270,2006年,研究論文(学術雑誌)
  • Molecular mechanisms of cardioprotection by taurine on ischemia-induced apoptosis in cultured cardiomyocytes,Kyoko Takahashi,Tomoka Takatani,Yoriko Uozumi,Takashi Ito,Takahisa Matsuda,Yasushi Fujio,Stephen W. Schaffer,Junichi Azuma,TAURINE 6,SPRINGER-VERLAG BERLIN,Vol. 583,p. 257-263,2006年,研究論文(学術雑誌)
  • No positive association between adrenergic receptor variants of alpha(2c)Del322-325, beta(1)Ser49, beta(1)Arg389 and the risk for heart failure in the Japanese population,S Nonen,H Okamoto,M Akino,Y Matsui,Y Fujio,M Yoshiyama,Y Takemoto,J Yoshikawa,J Azuma,A Kitabatake,BRITISH JOURNAL OF CLINICAL PHARMACOLOGY,BLACKWELL PUBLISHING,Vol. 60,No. 4,p. 414-417,2005年10月,研究論文(学術雑誌)
  • Constitutive activation of JAK3/STAT3 in colon carcinoma tumors and cell lines - Inhibition of JAK3/STAT3 signaling induces apoptosis and cell cycle arrest of colon carcinoma cells,Q Lin,R Lai,LR Chirieac,CP Li,VA Thomazy,L Grammatikakis,GZ Rassidakis,W Zhang,Y Fujio,K Kunisada,Hamilton, SR,HM Amin,AMERICAN JOURNAL OF PATHOLOGY,AMER SOC INVESTIGATIVE PATHOLOGY, INC,Vol. 167,No. 4,p. 969-980,2005年10月,研究論文(学術雑誌)
  • Platelet activating factor induces cytoskeletal reorganization through Rho family pathway in THP-1 macrophages,C Sumita,M Yamane,T Matsuda,M Maeda,T Nariai,Y Fujio,J Azuma,FEBS LETTERS,ELSEVIER SCIENCE BV,Vol. 579,No. 18,p. 4038-4042,2005年07月,研究論文(学術雑誌)
  • STAT3 mediates cardioprotection against ischemia/reperfusion injury through metallothionein induction in the heart,Y Oshima,Y Fujio,T Nakanishi,N Itoh,Y Yamamoto,S Negoro,K Tanaka,T Kishimoto,Kawase, I,J Azuma,CARDIOVASCULAR RESEARCH,ELSEVIER SCIENCE BV,Vol. 65,No. 2,p. 428-435,2005年02月,研究論文(学術雑誌)
  • N-cadherin-mediated cell adhesion determines the plasticity for cell alignment in response to mechanical stretch in cultured cardiomyocytes,T Matsuda,K Takahashi,T Nariai,T Ito,T Takatani,Y Fujio,J Azuma,BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,ACADEMIC PRESS INC ELSEVIER SCIENCE,Vol. 326,No. 1,p. 228-232,2005年01月,研究論文(学術雑誌)
  • Taurine inhibits apoptosis by preventing formation of the Apaf-1/caspase-9 apoptosome,T Takatani,K Takahashi,Y Uozumi,E Shikata,Y Yamamoto,T Ito,T Matsuda,SW Schaffer,Y Fujio,J Azuma,AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY,AMER PHYSIOLOGICAL SOC,Vol. 287,No. 4,p. C949-C953,2004年10月,研究論文(学術雑誌)
  • Leptin stimulates ischemia-induced retinal neovascularization - Possible role of vascular endothelial growth factor expressed in retinal endothelial cells,E Suganami,H Takagi,H Ohashi,K Suzuma,Suzuma, I,H Oh,D Watanabe,T Ojima,T Suganami,Y Fujio,K Nakao,Y Ogawa,N Yoshimura,DIABETES,AMER DIABETES ASSOC,Vol. 53,No. 9,p. 2443-2448,2004年09月,研究論文(学術雑誌)
  • Circulating interleukin-6 family cytokines and their receptors in patients with congestive heart failure,H Hirota,M Izumi,T Hamaguchi,S Sugiyama,E Murakami,K Kunisada,Y Fujio,Y Oshima,Y Nakaoka,K Yamauchi-Takihara,HEART AND VESSELS,SPRINGER,Vol. 19,No. 5,p. 237-241,2004年09月,研究論文(学術雑誌)
  • Signals through gp130 upregulate Wnt5a and contribute to cell adhesion in cardiac myocytes,Y Fujio,T Matsuda,Y Oshima,M Maeda,T Mohri,T Ito,T Takatani,M Hirata,Y Nakaoka,R Kimura,T Kishimoto,J Azuma,FEBS LETTERS,ELSEVIER SCIENCE BV,Vol. 573,No. 1-3,p. 202-206,2004年08月,研究論文(学術雑誌)
  • Pioglitazone induces plasma platelet activating factor-acetylhydrolase and inhibits platelet activating factor-mediated cytoskeletal reorganization in macrophage,C Sumita,M Maeda,Y Fujio,J Kima,J Fujitsu,S Kasayama,Yamamoto, I,J Azuma,BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS,ELSEVIER SCIENCE BV,Vol. 1673,No. 3,p. 115-121,2004年08月,研究論文(学術雑誌)
  • Expression of taurine transporter is regulated through the TonE (tonicity-responsive element)/TonEBP (TonE-binding protein) pathway and contributes to cytoprotection in HepG2 cells,T Ito,Y Fujio,M Hirata,T Takatani,T Matsuda,S Muraoka,K Takahashi,J Azuma,BIOCHEMICAL JOURNAL,PORTLAND PRESS LTD,Vol. 382,p. 177-182,2004年08月,研究論文(学術雑誌)
  • Selective inhibition of STAT3 induces apoptosis and G(1) cell cycle arrest in ALK-positive anaplastic large cell lymphoma,HM Amin,TJ McDonnell,YP Ma,Q Lin,Y Fujio,K Kunisada,Leventaki, V,P Das,GZ Rassidakis,C Cutler,LJ Medeiros,R Lai,ONCOGENE,NATURE PUBLISHING GROUP,Vol. 23,No. 32,p. 5426-5434,2004年07月,研究論文(学術雑誌)
  • Signal transducer and activator of transcription-3 activation contributes to high tissue inhibitor of metalloproteinase-1 expression in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma,R Lai,GZ Rassidakis,LJ Medeiros,L Ramdas,AH Goy,C Cutler,Y Fujio,K Kunisada,HM Amin,F Gilles,AMERICAN JOURNAL OF PATHOLOGY,AMER SOC INVESTIGATIVE PATHOLOGY, INC,Vol. 164,No. 6,p. 2251-2258,2004年06月,研究論文(学術雑誌)
  • Novel Insertional mutation in the bone morphogenetic protein receptor type II associated with sporadic primary pulmonary hypertension,S Sugiyama,H Hirota,M Yoshida,Y Takemura,Y Nakaoka,Y Shima,K Terai,M Izumi,Y Fujio,S Hasegawa,T Mano,Y Nakatsuchi,M Hori,K Yamauchi-Takihara,Kawase, I,CIRCULATION JOURNAL,BLACKWELL PUBLISHING ASIA,Vol. 68,No. 6,p. 592-594,2004年06月,研究論文(学術雑誌)
  • Taurine prevents the ischemia-induced apoptosis in cultured neonatal rat cardiomyocytes through Akt/caspase-9 pathway,T Takatani,K Takahashi,Y Uozumi,T Matsuda,T Ito,SW Schaffer,Y Fujio,J Azuma,BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,ACADEMIC PRESS INC ELSEVIER SCIENCE,Vol. 316,No. 2,p. 484-489,2004年04月,研究論文(学術雑誌)
  • CYP3A5 genotype did not impact on nifedipine disposition in healthy volunteers,T. Fukuda,S. Onishi,S. Fukuen,Y. Ikenaga,M. Ohno,M. Ohno,K. Hoshino,K. Matsumoto,A. Maihara,K. Momiyama,T. Ito,Y. Fujio,J. Azuma,Pharmacogenomics Journal,Vol. 4,No. 1,p. 34-39,2004年,研究論文(学術雑誌)
  • Homocysteine induces vascular endothelial growth factor expression in differentiated THP-1 macrophages,M Maeda,Yamamoto, I,Y Fujio,J Azuma,BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS,ELSEVIER SCIENCE BV,Vol. 1623,No. 1,p. 41-46,2003年09月,研究論文(学術雑誌)
  • Activation of gp130 transduces hypertrophic signal through interaction of scaffolding/docking protein Gab1 with tyrosine phosphatase SHP2 in cardiomyocytes,Y Nakaoka,K Nishida,Y Fujio,M Izumi,K Terai,Y Oshima,S Sugiyama,S Matsuda,S Koyasu,K Yamauchi-Takihara,T Hirano,Kawase, I,H Hirota,CIRCULATION RESEARCH,LIPPINCOTT WILLIAMS & WILKINS,Vol. 93,No. 3,p. 221-229,2003年08月,研究論文(学術雑誌)
  • Diabetic retinopathy possibly results from poor blood sugar control associated with MTHFR gene polymorphism in type 2 diabetic patients - Response to Yoshioka et al.,M Maeda,Yamamoto, I,M Fukuda,M Nishida,J Fujitsu,S Nonen,T Igarashi,T Motomura,M Inaba,Y Fujio,J Azuma,DIABETES CARE,AMER DIABETES ASSOC,Vol. 26,No. 6,p. 1948-1948,2003年06月
  • MTHFR gene polymorphism as a risk factor for diabetic retinopathy in type 2 diabetic patients without serum creatinine elevation,M Maeda,Yamamoto, I,M Fukuda,M Nishida,J Fujitsu,S Nonen,T Igarashi,T Motomura,M Inaba,Y Fujio,J Azuma,DIABETES CARE,AMER DIABETES ASSOC,Vol. 26,No. 2,p. 547-548,2003年02月
  • A novel role for cytokine signaling in cardiac remodeling,K Yamauchi-Takihara,H Hirota,Y Fujio,M Izumi,Y Oshima,Y Nakaoka,CARDIAC REMODELING AND FAILURE,KLUWER ACADEMIC PUBLISHERS,Vol. 5,p. 259-264,2003年,研究論文(国際会議プロシーディングス)
  • Specific cardiomyopathy caused by multisystemic lipid storage in Jordan's anomaly,Y Oshima,H Hirota,H Nagai,M Izumi,Y Nakaoka,T Osugi,Y Fujio,H Tateyama,M Kikui,K Yamauchi-Takihara,Kawase, I,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 106,No. 2,p. 280-281,2002年07月
  • Aldosterone augments endothelin-1-induced cardiac myocyte hypertrophy with the reinforcement of the JNK pathway,Y Oshima,Y Fujio,M Funamoto,S Negoro,M Izumi,Y Nakaoka,H Hirota,K Yamauchi-Takihara,Kawase, I,FEBS LETTERS,ELSEVIER SCIENCE BV,Vol. 524,No. 1-3,p. 123-126,2002年07月,研究論文(学術雑誌)
  • Bcl-xl reduces doxorubicin-induced myocardial damage but fails to control cardiac gene downregulation,K Kunisada,E Tone,S Negoro,Y Nakaoka,Y Oshima,T Osugi,M Funamoto,M Izumi,Y Fujio,H Hirota,K Yamauchi-Takihara,CARDIOVASCULAR RESEARCH,ELSEVIER SCIENCE BV,Vol. 53,No. 4,p. 936-943,2002年03月,研究論文(学術雑誌)
  • A case of hypereosinophilic syndrome presenting mid-ventricular obstruction,Y Nakaoka,K Iwahori,K Kunisada,Y Fujio,M Izumi,T Osugi,Y Oshima,H Hirota,K Yamauchi-Takihara,HEART AND VESSELS,SPRINGER-VERLAG,Vol. 16,No. 3,p. 121-124,2002年03月,研究論文(学術雑誌)
  • Cardiac-specific activation of signal transducer and activator of transcription 3 promotes vascular formation in the heart,T Osugi,Y Oshima,Y Fujio,M Funamoto,A Yamashita,S Negoro,K Kunisada,M Izumi,Y Nakaoka,H Hirota,M Okabe,K Yamauchi-Takihara,Kawase, I,T Kishimoto,JOURNAL OF BIOLOGICAL CHEMISTRY,AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC,Vol. 277,No. 8,p. 6676-6681,2002年02月,研究論文(学術雑誌)
  • Activation of Akt2 Inhibits anoikis and apoptosis induced by myogenic differentiation,Y Fujio,Y Mitsuuchi,Testa, JR,K Walsh,CELL DEATH AND DIFFERENTIATION,NATURE PUBLISHING GROUP,Vol. 8,No. 12,p. 1207-1212,2001年12月,研究論文(学術雑誌)
  • Protein kinase B/Akt activates c-Jun NH2-terminal kinase by increasing NO production in response to shear stress,YM Go,YC Boo,H Park,MC Maland,R Patel,KA Pritchard,Y Fujio,K Walsh,Darley-Usmar, V,H Jo,JOURNAL OF APPLIED PHYSIOLOGY,AMER PHYSIOLOGICAL SOC,Vol. 91,No. 4,p. 1574-1581,2001年10月,研究論文(学術雑誌)
  • Activation of signal transducer and activator of transcription 3 protects cardiomyocytes from hypoxia/reoxygenation-induced oxidative stress through the upregulation of manganese superoxide dismutase,S Negoro,K Kunisada,Y Fujio,M Funamoto,MI Darville,DL Eizirik,T Osugi,M Izumi,Y Oshima,Y Nakaoka,H Hirota,T Kishimoto,K Yamauchi-Takihara,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 104,No. 9,p. 979-981,2001年08月,研究論文(学術雑誌)
  • Bone morphogenetic protein-2 inhibits serum deprivation-induced apoptosis of neonatal cardiac myocytes through activation of the Smad1 pathway,M Izumi,Y Fujio,K Kunisada,S Negoro,E Tone,M Funamoto,T Osugi,Y Oshima,Y Nakaoka,T Kishimoto,K Yamauchi-Takihara,H Hirota,JOURNAL OF BIOLOGICAL CHEMISTRY,AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC,Vol. 276,No. 33,p. 31133-31141,2001年08月,研究論文(学術雑誌)
  • beta-amyloid peptide expression is sufficient for myotube death: Implications for human inclusion body myopathy,HW Querfurth,T Suhara,KM Rosen,DL McPhie,Y Fujio,G Tejada,RL Neve,LS Adelman,K Walsh,MOLECULAR AND CELLULAR NEUROSCIENCE,ACADEMIC PRESS INC,Vol. 17,No. 5,p. 793-810,2001年05月,研究論文(学術雑誌)
  • Cardiomyocyte grafting for cardiac repair: Graft cell death and anti-death strategies,M Zhang,D Methot,Poppa, V,Y Fujio,K Walsh,CE Murry,JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY,ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD,Vol. 33,No. 5,p. 907-921,2001年05月,研究論文(学術雑誌)
  • Glycoprotein 130 regulates cardiac myocyte survival in doxorubicin-induced apoptosis through phosphatidylinositol 3-kinase/Akt phosphorylation and Bcl-xL/caspase-3 interaction,S Negoro,H Oh,E Tone,K Kunisada,Y Fujio,K Walsh,T Kishimoto,K Yamauchi-Takihara,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 103,No. 4,p. 555-561,2001年01月,研究論文(学術雑誌)
  • Akt1/PKB upregulation leads to vascular smooth muscle cell hypertrophy and polyploidization,ML Hixon,C Muro-Cacho,MW Wagner,C Obejero-Paz,E Millie,Y Fujio,Y Kureishi,T Hassold,K Walsh,A Gualberto,JOURNAL OF CLINICAL INVESTIGATION,AMER SOC CLINICAL INVESTIGATION INC,Vol. 106,No. 8,p. 1011-1020,2000年10月,研究論文(学術雑誌)
  • Acute modulation of endothelial Akt/PKB activity alters nitric oxide-dependent vasomotor activity in vivo,ZY Luo,Y Fujio,Y Kureishi,RD Rudic,G Daumerie,D Fulton,WC Sessa,K Walsh,JOURNAL OF CLINICAL INVESTIGATION,AMER SOC CLINICAL INVESTIGATION INC,Vol. 106,No. 4,p. 493-499,2000年08月,研究論文(学術雑誌)
  • Isolation and characterization of the murine cardiotrophin-1 gene: Expression and norepinephrine-induced transcriptional activation,M Funamoto,S Hishinuma,Y Fujio,Y Matsuda,K Kunisada,H Oh,S Negoro,E Tone,T Kishimoto,K Yamauchi-Takihara,JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY,ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD,Vol. 32,No. 7,p. 1275-1284,2000年07月,研究論文(学術雑誌)
  • Vascular endothelial growth factor-stimulated actin reorganization and migration of endothelial cells is regulated via the serine/threonine kinase Akt,M Morales-Ruiz,D Fulton,G Sowa,LR Languino,Y Fujio,K Walsh,WC Sessa,CIRCULATION RESEARCH,LIPPINCOTT WILLIAMS & WILKINS,Vol. 86,No. 8,p. 892-896,2000年04月,研究論文(学術雑誌)
  • Signal transducer and activator of transcription 3 is required for glycoprotein 130-mediated induction of vascular endothelial growth factor in cardiac myocytes,M Funamoto,Y Fujio,K Kunisada,S Negoro,E Tone,T Osugi,H Hirota,M Izumi,K Yoshizaki,K Walsh,T Kishimoto,K Yamauchi-Takihara,JOURNAL OF BIOLOGICAL CHEMISTRY,AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC,Vol. 275,No. 14,p. 10561-10566,2000年04月,研究論文(学術雑誌)
  • Akt promotes survival of cardiomyocytes in vitro and protects against ischemia-reperfusion injury in mouse heart,Y Fujio,T Nguyen,D Wencker,RN Kitsis,K Walsh,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 101,No. 6,p. 660-667,2000年02月,研究論文(学術雑誌)
  • Hypoxic stress induces cardiotrophin-1 expression in cardiac myocytes,S Hishinuma,M Funamoto,Y Fujio,K Kunisada,K Yamauchi-Takihara,BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,ACADEMIC PRESS INC,Vol. 264,No. 2,p. 436-440,1999年10月,研究論文(学術雑誌)
  • Reactive oxygen species mediate the activation of Akt/protein kinase B by angiotensin II in vascular smooth muscle cells,M Ushio-Fukai,RW Alexander,M Akers,QQ Yin,Y Fujio,K Walsh,KK Griendling,JOURNAL OF BIOLOGICAL CHEMISTRY,AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC,Vol. 274,No. 32,p. 22699-22704,1999年08月,研究論文(学術雑誌)
  • Cell cycle withdrawal promotes myogenic induction of Akt, a positive modulator of myocyte survival,Y Fujio,K Guo,T Mano,Y Mitsuuchi,Testa, JR,K Walsh,MOLECULAR AND CELLULAR BIOLOGY,AMER SOC MICROBIOLOGY,Vol. 19,No. 7,p. 5073-5082,1999年07月,研究論文(学術雑誌)
  • Regulation of endothelium-derived nitric oxide production by the protein kinase Akt,D Fulton,JP Gratton,TJ McCabe,J Fontana,Y Fujio,K Walsh,TF Franke,A Papapetropoulos,WC Sessa,NATURE,MACMILLAN MAGAZINES LTD,Vol. 399,No. 6736,p. 597-601,1999年06月,研究論文(学術雑誌)
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  • Induction of interleukin (IL)-6 by hypoxia is mediated by nuclear factor (NF)-kappa B and NF-IL6 in cardiac myocytes,H Matsui,Y Ihara,Y Fujio,K Kunisada,S Akira,T Kishimoto,K Yamauchi-Takihara,CARDIOVASCULAR RESEARCH,ELSEVIER SCIENCE BV,Vol. 42,No. 1,p. 104-112,1999年04月,研究論文(学術雑誌)
  • Angiotensin II interferes with leukemia inhibitory factor-induced STAT3 activation in cardiac myocytes,E Tone,K Kunisada,Y Fujio,H Matsui,S Negoro,H Oh,T Kishimoto,K Yamauchi-Takihara,BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,ACADEMIC PRESS INC,Vol. 253,No. 1,p. 147-150,1998年12月,研究論文(学術雑誌)
  • Activation of gp130 transduces hypertrophic signals via STAT3 in cardiac myocytes,K Kunisada,E Tone,Y Fujio,H Matsui,K Yamauchi-Takihara,T Kishimoto,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 98,No. 4,p. 346-352,1998年07月,研究論文(学術雑誌)
  • Activation of phosphatidylinositol 3-kinase through glycoprotein 130 induces protein kinase B and p70 S6 kinase phosphorylation in cardiac myocytes,H Oh,Y Fujio,K Kunisada,H Hirota,H Matsui,T Kishimoto,K Yamauchi-Takihara,JOURNAL OF BIOLOGICAL CHEMISTRY,AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC,Vol. 273,No. 16,p. 9703-9710,1998年04月,研究論文(学術雑誌)
  • Signals through gp130 upregulate bcl-x gene expression via STAT1-binding cis-element in cardiac myocytes,Y Fujio,K Kunisada,H Hirota,K YamauchiTakihara,T Kishimoto,JOURNAL OF CLINICAL INVESTIGATION,ROCKEFELLER UNIV PRESS,Vol. 99,No. 12,p. 2898-2905,1997年06月,研究論文(学術雑誌)
  • Novel missense mutation in cardiac troponin T gene found in Japanese patient with hypertrophic cardiomyopathy,C NakajimaTaniguchi,H Matsui,Y Fujio,S Nagata,T Kishimoto,K YamauchiTakihara,JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY,ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD,Vol. 29,No. 2,p. 839-843,1997年02月,研究論文(学術雑誌)
  • Activation of JAK-STAT and MAP kinases by leukemia inhibitory factor through gp130 in cardiac myocytes,K Kunisada,H Hirota,Y Fujio,H Matsui,Y Tani,K YamauchiTakihara,T Kishimoto,CIRCULATION,AMER HEART ASSOC,Vol. 94,No. 10,p. 2626-2632,1996年11月,研究論文(学術雑誌)
  • Leukemia inhibitory factor induces a hypertrophic response mediated by GP130 in murine cardiac myocytes,H Matsui,Y Fujio,K Kunisada,H Hirota,K YamauchiTakihara,RESEARCH COMMUNICATIONS IN MOLECULAR PATHOLOGY AND PHARMACOLOGY,P J D PUBLICATIONS LTD,Vol. 93,No. 2,p. 149-162,1996年08月,研究論文(学術雑誌)
  • Clinical implications of hypertrophic cardiomyopathy associated with mutations in the alpha-tropomyosin gene,K YamauchiTakihara,C NakajimaTaniguchi,H Matsui,Y Fujio,K Kunisada,S Nagata,T Kishimoto,HEART,BRITISH MED JOURNAL PUBL GROUP,Vol. 76,No. 1,p. 63-65,1996年07月,研究論文(学術雑誌)
  • Roles of gp130 signaling pathways in cardiac myocytes: Recent advances and implications for cardiovascular disease,Keiko Yamauchi-Takihara,Hisao Hirota,Keita Kunisada,Hideo Matsui,Yasushi Fujio,Tetsuya Taga,Tadamitsu Kishimoto,Journal of Cardiac Failure,Churchill Livingstone Inc.,Vol. 2,No. 1,p. S63-S67,1996年,研究論文(学術雑誌)
  • Elevated calcium level induces calcium-dependent proteolysis of A-CAM (N-cadherin) in heart - Analysis by detergent-treated model,N Sato,Y Fujio,F YamadaHonda,H Funai,A Wada,S Kawashima,N Awata,N Shibata,BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS,Vol. 217,No. 2,p. 649-653,1995年12月,研究論文(学術雑誌)
  • Disruption of cell-cell adhesion in an inbred strain of hereditary cardiomyopathic hamster (bio 14.6),Y Fujio,F YamadaHonda,N Sato,H Funai,A Wada,N Awata,N Shibata,CARDIOVASCULAR RESEARCH,ELSEVIER SCIENCE BV,Vol. 30,No. 6,p. 899-904,1995年12月,研究論文(学術雑誌)
  • ALTERED FIBRONECTIN-DEPENDENT CELL-ADHESION BY PDGF ACCOMPANIES PHENOTYPIC MODULATION OF VASCULAR SMOOTH-MUSCLE CELLS,Y FUJIO,F YAMADA,K TAKAHASHI,N SHIBATA,BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS,Vol. 196,No. 2,p. 997-1002,1993年10月,研究論文(学術雑誌)
  • RESPONSES OF SMOOTH-MUSCLE CELLS TO PLATELET-DERIVED GROWTH-FACTOR ARE INHIBITED BY HERBIMYCIN-A TYROSINE KINASE INHIBITOR,Y FUJIO,F YAMADA,K TAKAHASHI,N SHIBATA,BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS,Vol. 195,No. 1,p. 79-83,1993年08月,研究論文(学術雑誌)
  • STRUCTURAL AND FUNCTIONAL-RELATIONSHIPS BETWEEN H-CALDESMONS AND L-CALDESMONS,K HAYASHI,Y FUJIO,KATO, I,K SOBUE,JOURNAL OF BIOLOGICAL CHEMISTRY,AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC,Vol. 266,No. 1,p. 355-361,1991年01月,研究論文(学術雑誌)
  • Immunochemical evidence that myosin i heavy chain-like protein is identical to the 110-kilodalton brush-border protein,Minoru Hoshimaru,Yasushi Fujio,Kenji Sobue,Tetsuo Sugimoto,Shigetada Nakanishi,Journal of Biochemistry,Oxford University Press,Vol. 106,No. 3,p. 455-459,1989年,研究論文(学術雑誌)
  • Significances of two different Mr caldesmons.,Sobue K,Fujio Y,In Calcium Protein Signaling, Plenum Publishing Corporation,p. 325-335,1989年
  • TUMOR PROMOTER INDUCES REORGANIZATION OF ACTIN-FILAMENTS AND CALSPECTIN (FODRIN OR NONERYTHROID SPECTRIN) IN 3T3 CELLS,K SOBUE,Y FUJIO,K KANDA,PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,NATL ACAD PRESS,Vol. 85,No. 2,p. 482-486,1988年01月,研究論文(学術雑誌)
  • IMMUNOCYTOCHEMICAL LOCALIZATION OF CALSPECTIN (A NONERYTHROID SPECTRIN-LIKE PROTEIN) IN THYROID-GLANDS OF NORMAL AND TSH-TREATED RATS,K ISHIMURA,T SENDA,K KITAJIMA,H FUJITA,Y FUJIO,K SOBUE,HISTOCHEMISTRY,SPRINGER VERLAG,Vol. 86,No. 6,p. 537-539,1987年,研究論文(学術雑誌)

MISC

  • Progesterone receptor membrane component 1 leads to erlotinib resistance, initiating crosstalk of Wnt/β-catenin and NF-κB pathways, in lung adenocarcinoma cells.,Ying Lin,Kazuma Higashisaka,Takuya Shintani,Ayaka Maki,Sachiyo Hanamuro,Yuya Haga,Shinichiro Maeda,Hirofumi Tsujino,Kazuya Nagano,Yasushi Fujio,Yasuo Tsutsumi,Scientific reports,Vol. 10,No. 1,p. 4748-4748,2020年03月16日
  • Suppression of transcription factor OASIS ameliorated kidney fibrosis.,Masanori Obana,Ayaha Yamamoto,Takafumi Nakae,Yoshiaki Miyake,Takeo Harada,Sayuri Mitsuoka,Shunsuke Noda,Makiko Maeda,Kazunori Imaizumi,Kotaro Matsumoto,Yasushi Fujio,ASN Kidney Week 2019 Annual Meeting,2019年11月,研究発表ペーパー・要旨(国際会議)
  • 日本におけるPharm D.制度の推進 Pharm D(大阪大学)コース 臨床科学に貢献するPharmacist-Scientistの育成を目指して,藤尾 慈,前田 真一郎,宇野 公之,日本薬剤学会年会講演要旨集,(公社)日本薬剤学会,Vol. 32年会,p. 78-78,2017年05月
  • Heterozygous Ablation of ROR gamma t Gene Deteriorates Adverse Cardiac Remodeling After Myocardial Infarction,Daichi Enomoto,Masanori Obana,Kotaro Matsumoto,Yasushi Sakata,Makiko Maeda,Hiroyuki Nakayama,Yasushi Fujio,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 134,2016年11月,研究発表ペーパー・要旨(国際会議)
  • Adult Mammalian Hearts Restore Intrinsic Regenerative Capacity Through Signal Transducer and Activation of Transcription 3 in the Resolution Phase of Myocarditis,Akimitsu Miyawaki,Masanori Obana,Yusuke Mitsuhara,Aya Orimoto,Yusuke Nakayasu,Tomomi Yamashita,So-ichiro Fukada,Makiko Maeda,Yasushi Sakata,Hiroyuki Nakayama,Yasushi Fujio,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 134,2016年11月,研究発表ペーパー・要旨(国際会議)
  • Myeloid Cell Derived Leucine Rich alpha 2 Glycoprotein Attenuates Adverse Cardiac Remodeling After Myocardial Infarction,Shohei Kumagai,Hiroyuki Nakayama,Minoru Fujimoto,Hiromi Honda,Satoshi Serada,Atsushi Kasai,Masanori Obana,Yasushi Sakata,Yoshiki Sawa,Tetsuji Naka,Yasushi Fujio,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 132,2015年11月,研究発表ペーパー・要旨(国際会議)
  • Cardiac STAT3 Activation in Subacute Phase of Myocardial Infarction was Required for the Suppression of Adverse Cardiac Remodeling,Daichi Enomoto,Masanori Obana,Akimitsu Miyawaki,Tomomi Mohri,Makio Maeda,Yasushi Sakata,Hiroyuki Nakayama,Yasushi Fujio,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 132,2015年11月,研究発表ペーパー・要旨(国際会議)
  • Caveolae-Specific Phosphorylation of L-type Calcium Channel beta 2a Subunit Exacerbates Cardiac Hypertrophy,Shohei Kumagai,Nao Hayamizu,Sachi Matsunami,Wataru Otsuka,Yasushi Sakata,Yasushi Fujio,Hiroyuki Nakayama,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 130,2014年11月,研究発表ペーパー・要旨(国際会議)
  • Vascular functional and morphological alterations in smokers with varenicline therapy,M. Kobayashi,Y. Takemoto,T. Shuto,N. Norioka,T. Iguchi,M. Maeda,Y. Fujio,J. Azuma,M. Yoshiyama,K. Hirohashi,EUROPEAN HEART JOURNAL,OXFORD UNIV PRESS,Vol. 35,p. 902-903,2014年09月,研究発表ペーパー・要旨(国際会議)
  • 創薬研究のパラダイムシフト―難治性疾患の分子創薬―循環器疾患における新規サイトカイン治療,大和田康子,前田真貴子,藤尾慈,臨床化学,(一社)日本臨床化学会,Vol. 43,No. 3,p. 191-196,2014年07月31日
  • Phosphorylation of L-type Ca2+ channel beta 2a subunit induces cardiomyocyte hypertrophy,Nao Hayamizu,Shohei Kumagai,Sachi Matsunami,Hiroyuki Nakayama,Yasushi Fujio,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 124,p. 134P-134P,2014年,研究発表ペーパー・要旨(国際会議)
  • Excessive BIN1 expression results in adverse remodeling through cardiomyocyte death,Kota Tonegawa,Sachi Matsunami,Daisuke Tsuchiyama,Hiroyuki Nakayama,Yasushi Fujio,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 124,p. 87P-87P,2014年,研究発表ペーパー・要旨(国際会議)
  • The macrophage-specific overexpression of CD93 enhances phagocytosis and ameliorates cardiac fibrosis after myocardial infarction,Kana Takewaki,Tomomi Yamashita,Kaori Miyamoto,Tomomi Mohri,Hiroyuki Nakayama,Yasushi Fujio,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 124,p. 87P-87P,2014年,研究発表ペーパー・要旨(国際会議)
  • 心筋梗塞慢性期における心筋特異的STAT3の欠損は心筋リモデリングを悪化させる,榎本大智,尾花理徳,宮脇昭光,毛利友美,前田真貴子,中山博之,藤尾慈,生体機能と創薬シンポジウム要旨集,Vol. 2014,2014年
  • ニコチン代謝酵素CYP2A6遺伝子多型と呼気CO濃度の関係,前田真貴子,杉浦知佳,志賀遼太,松岡翔太,竹ノ内拓也,中西和親,山川剛,藤尾慈,東純一,臨床薬理,(一社)日本臨床薬理学会,Vol. 44,No. Supplement,p. S256-S256,2013年11月14日
  • 急性心筋梗塞に対するインターロイキン11(IL-11)製剤を用いた心筋保護治療の臨床試験のためのプロトコール作成研究,大和田 康子,泉 康雄,朝倉 正紀,山本 晴子,前田 真貴子,葭山 稔,藤尾 慈,臨床薬理,(一社)日本臨床薬理学会,Vol. 44,No. Suppl.,p. S248-S248,2013年11月
  • Cathelicidin antimicrobial peptide inhibits fibroblasts migration via P2X7 receptor signaling,Shohei Kumagai,Hiroyuki Nakayama,Kazuki Matsui,Haruyo Kawaguchi,Akimitsu Miyawaki,Tomomi Yamashita,Yasushi Fujio,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 121,p. 77P-77P,2013年,研究発表ペーパー・要旨(国際会議)
  • Development of a novel tool for analysis of PKA and CaMKII activities in caveolae microdomain,Sachi Matsunami,Nao Hayamizu,Hiroyuki Nakayama,Yasushi Fujio,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 121,p. 97P-97P,2013年,研究発表ペーパー・要旨(国際会議)
  • Regulatory T cells (Tregs) ameliorate myocardial infarction (MI)-induced cardiac remodeling in mice,Shiori Taga,Tomomi Yamashita,Hiroyuki Nakayama,Yasushi Fujio,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 121,p. 83P-83P,2013年,研究発表ペーパー・要旨(国際会議)
  • The myocardial activation of CaMKII beta leads to heart failure,Komayu Wajima,Hiroyuki Nakayama,Tatsuto Hamatani,Sachi Matsunami,Shohei Kumagai,Tomomi Yamashita,Yasushi Fujio,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 121,p. 84P-84P,2013年,研究発表ペーパー・要旨(国際会議)
  • Association of Paraoxonase 1 gene polymorphism with intima-media thickness (IMT) of the carotid arteries in Japanese type 2 diabetic patients,I. Yamamoto,T. Honda,K. Takada,M. Maeda,S. Nonen,T. Motomura,K. Maeda,Y. Fujio,J. Azuma,DIABETES-METABOLISM RESEARCH AND REVIEWS,WILEY-BLACKWELL,Vol. 28,p. 94-94,2012年12月,研究発表ペーパー・要旨(国際会議)
  • Treg is Recruited Into Myocardium Through Th17 Pathway as a Negative Feedback in Autoimmune Myocarditis,Tomomi Yamashita,Rie Torii,Issei Komuro,Hiroyuki Nakayama,Yasushi Fujio,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 126,No. 21,2012年11月,研究発表ペーパー・要旨(国際会議)
  • 喫煙者におけるインターロイキン‐6(IL‐6)遺伝子プロモーター領域の遺伝子多型が肥満とニコチン依存に及ぼす影響,前田真貴子,竹本恭彦,船本全信,藤尾慈,東純一,臨床薬理,(一社)日本臨床薬理学会,Vol. 43,No. Supplement,p. S249-S249,2012年10月31日
  • Cardiac-Specific Overexpression of Runx2 Mediates Cardiac Hypertrophy and Dysfunction in Mice,Hiroyuki Nakayama,Tatsuto Hamatani,Shohei Kumagai,Kota Tonegawa,Tomomi Yamashita,Yasushi Fujio,CIRCULATION RESEARCH,LIPPINCOTT WILLIAMS & WILKINS,Vol. 111,No. 4,2012年08月,研究発表ペーパー・要旨(国際会議)
  • Genetic variation of osteopontin G-156del effectively predicts mortality and responsiveness to carvedilol: Japanese chronic heart failure (J-CHF) study,Hiroshi Okamoto,Yasushi Fujio,Shinpei Nonen,Jyunichi Azuma,Masatsugu Hori,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 125,No. 19,p. E691-E691,2012年05月,研究発表ペーパー・要旨(国際会議)
  • インターロイキン-11は心筋STAT3を介して虚血再灌流におけるpost-conditioning効果を惹起する,中山 博之,尾花 正徳,前田 真貴子,松宮 護郎,葭山 稔,小室 一成,藤尾 慈,日本臨床分子医学会学術総会プログラム・抄録集,日本臨床分子医学会,Vol. 49回,p. 91-91,2012年04月
  • Calcium-mediated pathogenesis in heart,Hiroyuki Nakayama,Yasushi Fujio,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 118,p. 15P-15P,2012年,研究発表ペーパー・要旨(国際会議)
  • The ablation of ROR gamma t gene results in advanced cardiac fibrosis after Myocardial Infarction,Tomomi Yamashita,Masanori Obana,Akiko Hayama,Hiroyuki Nakayama,Yasushi Fujio,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 118,p. 76P-76P,2012年,研究発表ペーパー・要旨(国際会議)
  • The myocardial expression of tumor necrosis factor-stimulated gene-6 (TSG-6) increases at the end of inflammation in experimental autoimmune myocarditis (EAM).,Haruyo Kawaguchi,Tomomi Yamashita,Rie Torii,Hiroyuki Nakayama,Yasushi Fujio,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 118,p. 241P-241P,2012年,研究発表ペーパー・要旨(国際会議)
  • Cardiac-specific overexpression of Runx2 mediates cardiac hypertrophy in mice.,Tatsuto Hamatani,Hiroyuki Nakayama,Sachi Matsunami,Reo Matsuo,Yasushi Fujio,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 118,p. 201P-201P,2012年,研究発表ペーパー・要旨(国際会議)
  • Th17 Cells Exhibit Protective Effects Against Cardiac Fibrosis After Myocardial Infarction,Tomomi Yamashita,Masanori Obana,Akiko Hayama,Tomohiko Iwakura,Issei Komuro,Hiroyuki Nakayama,Yasushi Fujio,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 124,No. 21,2011年11月,研究発表ペーパー・要旨(国際会議)
  • 喫煙による薬物代謝酵素UGT1A1誘導に対する核内レセプターCAR及びAhRの関与,志賀遼太,杉浦知佳,前田真貴子,東純一,藤尾慈,臨床薬理,(一社)日本臨床薬理学会,Vol. 42,No. Supplement,p. S234-S234,2011年10月31日
  • COPD ニコチン依存の遺伝子解析,前田真貴子,藤尾慈,東純一,日本臨床,Vol. 69,No. 10,p. 1887-1890,2011年10月01日
  • 禁煙治療薬の個別化適正投与法確立に向けたゲノム薬理学的研究,前田真貴子,藤尾慈,東純一,臨床薬理の進歩,(公財)臨床薬理研究振興財団,No. 32,p. 127-135,2011年06月20日
  • GENETIC POLYMORPHISMS OF CYP17A1 MAY PREDICT EARLY PROGRESSION AFTER PRIMARY ANDROGEN DEPRIVATION THERAPY IN JAPANESE MEN WITH PROSTATE CANCER,Masashi Nakayama,Takeshi Yamada,Tomohito Shimizu,Shinpei Nonen,Kensaku Nishimura,Kazuo Nishimura,Tsuneo Hara,Go Tanigawa,Toshiaki Yoshioka,Koji Hatano,Yasutomo Nakai,Hitoshi Takayama,Yasushi Fujio,Junichi Azuma,Akihiko Okuyama,Norio Nonomura,JOURNAL OF UROLOGY,ELSEVIER SCIENCE INC,Vol. 185,No. 4,p. E918-E918,2011年04月,研究発表ペーパー・要旨(国際会議)
  • ニコチン性アセチルコリン受容体α4サブユニット遺伝子多型rs2273504とニコチン依存度との関連について,前田真貴子,杉浦知佳,志賀遼太,藤尾慈,東純一,日本薬学会年会要旨集,(公社)日本薬学会,Vol. 131st,No. 3,p. 165-165,2011年03月05日
  • Disruption of leptin signal exacerbates myocardial injury by enhancing ER stress after myocardial infarction,Momoko Shiragaki,Masanori Obana,Shiho Murasawa,Kaori Miyamoto,Hiroyuki Nakayama,Yasushi Fujio,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 115,p. 111P-111P,2011年,研究発表ペーパー・要旨(国際会議)
  • Olmesartan attenuates angiotensin II induced interleukin-23 production in cardiac fibroblast,Kohei Katayama,Akiko Hayama,Tomomi Yamasita,Shiho Murasawa,Hiroyuki Nakayama,Yasushi Fujio,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 115,p. 108P-108P,2011年,研究発表ペーパー・要旨(国際会議)
  • Th17 cells are indispensable for myocardial inflammation in autoimmune myocarditis,Tomomi Yamashita,Hiroyuki Nakayama,Yasushi Fujio,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 115,p. 88P-88P,2011年,研究発表ペーパー・要旨(国際会議)
  • PTP1B negatively regulates JAK/STAT cardioprotective signaling in cardiomyocytes,Shiho Murasawa,Masanori Obana,Tomohiko Iwakura,Kazuki Matsui,Momoko Shiragaki,Kohei Katayama,Kaori Miyamoto,Junichi Azuma,Hiroyuki Nakayama,Yasushi Fujio,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 115,p. 89P-89P,2011年,研究発表ペーパー・要旨(国際会議)
  • DOCKING PROTEIN GAB1 IS ESSENTIAL FOR HGF-DEPENDENT ENDOTHELIAL SIGNALING AND ANGIOGENESIS AFTER HINDLIMB ISCHEMIA,Yoshikazu Nakaoka,Wataru Shioyama,Kaori Higuchi,Yo Arita,Fumihiro Sanada,Yoshiaki Taniyama,Ryuichi Morishita,Tadashi Kuroda,Yasushi Fujio,Keiko Yamauchi-Takihara,Naoki Mochizuki,Issei Komuro,JOURNAL OF GENE MEDICINE,JOHN WILEY & SONS LTD,Vol. 12,No. 12,p. 1050-1051,2010年12月,研究発表ペーパー・要旨(国際会議)
  • 喫煙による薬物代謝酵素CYP2B6誘導に対する核内レセプターCARの関与,志賀遼太,杉浦知佳,鷲尾育美,前田真貴子,吉田光宏,南畝晋平,藤尾慈,東純一,臨床薬理,(一社)日本臨床薬理学会,Vol. 41,No. Supplement,p. S284-S284,2010年11月10日
  • Gab1 Attenuates Angiotensin II-accelerated Atherosclerosis in Apolipoprotein E Deficient Mice via HGF/c-Met Signaling Pathway,Kaori Higuchi,Yoshikazu Nakaoka,Wataru Shioyama,Yoshiaki Taniyama,Yoh Arita,Takahiro Hashimoto,Yasushi Fujio,Keiko Yamauchi-Takihara,Ryuichi Morishita,Toshio Hirano,Naoki Mochizuki,Issei Komuro,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 122,No. 21,2010年11月,研究発表ペーパー・要旨(国際会議)
  • 科学的根拠に基づく禁煙支援に向けたニコチン依存形成に関するファーマコゲノミクス(ゲノム薬理学)研究の進捗状況,前田真貴子,薗はじめ,薗潤,杉浦知佳,志賀遼太,今本千衣子,加藤正隆,木下正治,竹本恭彦,田那村雅子,内藤毅郎,西耕一,能登啓文,船本全信,松岡宏,村松弘康,森田純二,山田修久,作田学,藤尾慈,東純一,日本禁煙学会学術総会プログラム・抄録集,(一社)日本禁煙学会,Vol. 5th,p. 51-51,2010年09月19日
  • Calcium-mediated Cell Death in Heart Failure,Hiroyuki Nakayama,Yasushi Fujio,JOURNAL OF CARDIAC FAILURE,CHURCHILL LIVINGSTONE INC MEDICAL PUBLISHERS,Vol. 16,No. 9,p. S133-S133,2010年09月,研究発表ペーパー・要旨(国際会議)
  • Cardiac and skeletal muscle abnormality in taurine transporter-knockout mice,Takashi Ito,Shohei Oishi,Mika Takai,Yasushi Kimura,Yoriko Uozumi,Yasushi Fujio,Stephen W. Schaffer,Junichi Azuma,JOURNAL OF BIOMEDICAL SCIENCE,BIOMED CENTRAL LTD,Vol. 17,2010年08月,書評論文,書評,文献紹介等
  • 心臓血管の発生,疾患に関与する新しい注目すべき分子 IL‐11の心血管系における作用,尾花理徳,前田真貴子,藤尾慈,循環器内科,(有)科学評論社,Vol. 67,No. 2,p. 156-162,2010年02月28日
  • 虚血再灌流傷害におけるIL‐11のpost‐conditioning効果について,宮本香織,尾花理徳,前田真貴子,東純一,中山博之,藤尾慈,日本薬理学会近畿部会プログラム・要旨集,Vol. 118th,2010年
  • ニコチン代謝酵素CYP2A6遺伝子多型のニコチン依存強度に与える影響,杉浦知佳,前田真貴子,植木理紗,谷口智子,船本全信,三浦源太,鷲尾育美,久保田智子,竹本恭彦,南畝晋平,藤尾慈,東純一,臨床薬理,(一社)日本臨床薬理学会,Vol. 40,No. Supplement,p. S183-S183,2009年11月18日
  • Interaction of Docking Protein Gab1 With Tyrosine Phosphatase SHP2 Regulates Hepatocyte Growth Factor-dependent ERK5 Activation and Upregulation of KLF2 in the Vascular Endothelium,Wataru Shioyama,Yoshikazu Nakaoka,Kaori Higuchi,Takashi Minami,Takao Hamakubo,Yoh Arita,Kaori Yamamoto,Hiroyasu Kidoya,Hisamichi Naito,Nobuyuki Takakura,Yasushi Fujio,Keiko Yamauchi-Takihara,Toshio Hirano,Tatsuhiko Kodama,Naoki Mochizuki,Issei Komuro,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 120,No. 18,p. S1152-S1152,2009年11月,研究発表ペーパー・要旨(国際会議)
  • Scaffolding Docking Protein Gab1 Has an Essential Role for HGF-Dependent Endothelial Signaling and Angiogenesis After Hindlimb Ischemia,Yoshikazu Nakaoka,Wataru Shioyama,Kaori Higuchi,Yoh Arita,Yasushi Fujio,Keiko Yamauchi-Takihara,Naoki Mochizuki,Issei Komuro,CIRCULATION RESEARCH,LIPPINCOTT WILLIAMS & WILKINS,Vol. 105,No. 7,p. E52-E52,2009年09月,研究発表ペーパー・要旨(国際会議)
  • 科学的根拠に基づく禁煙支援に向けたニコチン依存形成に関するファーマコゲノミクス(ゲノム薬理学)研究 禁煙学会認定研究としての進め方について,東 純一,前田 真貴子,薗 潤,薗 はじめ,杉浦 知佳,稲本 望,今本 千衣子,清水 隆裕,竹本 恭彦,能登 啓文,山代 寛,山田 修久,藤尾 慈,作田 学,日本禁煙学会学術総会プログラム・抄録集,(一社)日本禁煙学会,Vol. 4回,p. 48-48,2009年09月
  • ニコチン代謝酵素CYP2A6遺伝子多型のニコチン依存強度に与える影響,杉浦 知佳,前田 真貴子,植木 理紗,谷口 智子,船本 全信,蓮沼 智子,三浦 源太,丹下 悦子,鷲尾 育美,久保田 智子,増永 結子,南畝 晋平,藤尾 慈,東 純一,日本禁煙学会学術総会プログラム・抄録集,(一社)日本禁煙学会,Vol. 4回,p. 92-92,2009年09月
  • 「薬が効かない」を科学する 1 レスポンダーとノンレスポンダー,藤尾慈,前田真貴子,東純一,医薬ジャーナル,Vol. 45,No. 4,p. 1175-1179,2009年04月01日
  • 「薬が効かない」を科学する(新連載・1)レスポンダーとノンレスポンダー,藤尾 慈,前田 真貴子,東 純一,医薬ジャ-ナル,医薬ジャ-ナル社,Vol. 45,No. 4,p. 125-129,2009年04月
  • CYP2B6遺伝子多型はニコチン依存度に影響を及ぼさない,鷲尾 育美,前田 真貴子,谷口 智子,船本 全信,蓮沼 智子,三浦 源太,山本 明子,増永 結子,南畝 晋平,藤尾 慈,東 純一,臨床薬理,(一社)日本臨床薬理学会,Vol. 39,No. Suppl.,p. S213-S213,2008年11月
  • The Association of Osteopontin with Cardiac Fibrosis and the Responsiveness to Beta-Blockers in Patients with Heart Failure,Hiroshi Okamoto,Shinpei Nonen,Yasushi Fujio,Yutaka Matsui,Yasuhiko Takemoto,Minoru Yoshiyama,Junichi Yoshikawa,Akira Kitabatake,Junichi Azuma,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 118,No. 18,p. S955-S955,2008年10月,研究発表ペーパー・要旨(国際会議)
  • SHP2 Negatively Regulates Skeletal alpha-actin Gene Expression Downstream of LIF-dependent Hypertrophic Signaling in Cardiomyocytes,Wataru Shioyama,Yoshikazu Nakaoka,Yasushi Fujio,Keiko Yamauchi-Takihara,Naoki Mochizuki,JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY,ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD,Vol. 45,p. S18-S18,2008年10月,研究発表ペーパー・要旨(国際会議)
  • Scaffolding Docking Protein Gab1 Is Essential for HGF-Mediated Endothelial Signaling and Angiogenesis after Hind-Limb Ischemia,Yoshimune Hiramoto,Wataru Shioyama,Kaori Higuchi,Kitaro Okamoto,Yo Arita,Tadashi Kuroda,Fumihiro Sanada,Yoshiaki Taniyama,Ryuichi Morishita,Keigo Nishida,Yasushi Fujio,Keiko Yamauchi-Takihara,Toshio Hirano,Naoki Mochizuki,Yoshikazu Nakaoka,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 118,No. 18,p. S549-S550,2008年10月,研究発表ペーパー・要旨(国際会議)
  • 科学的根拠に基づく禁煙支援に向けたニコチン依存形成に関するファーマコゲノミクス(ゲノム薬理学)研究,東純一,前田真貴子,薗潤, 薗はじめ,鷲尾育美,杉浦知佳,藤尾慈,日本禁煙学会学術総会プログラム・抄録集,(一社)日本禁煙学会,Vol. 3rd,p. 59-59,2008年08月09日
  • Interaction of Scaffolding Adaptor Protein Gab1 with Tyrosine Phosphatase SHP2 Negatively Regulates IGF-I-Dependent Myogenic Differentiation via ERK1/2 Signaling Pathway,Yoshikazu Nakaoka,Tatsuya Koyama,Kitaro Okamoto,Wataru Shioyama,Keigo Nishida,Yasushi Fujio,Toshio Hirano,Naoki Mochizuki,CIRCULATION RESEARCH,LIPPINCOTT WILLIAMS & WILKINS,Vol. 103,No. 5,p. E59-E59,2008年08月,研究発表ペーパー・要旨(国際会議)
  • 喫煙と薬の相互作用~薬物代謝酵素チトクロームP450 1A2の誘導による影響を中心に~,前田真貴子,増永結子,大野雅子,藤尾慈,東純一,日本禁煙学会雑誌,(一社)日本禁煙学会,Vol. 3,No. 4,p. 63-65,2008年08月01日
  • 日本人においてニコチン依存に影響を及ぼす遺伝子多型の探索,鷲尾 育美,前田 真貴子,植木 理紗,谷口 智子,船本 全信,蓮沼 智子,三浦 源太,山本 明子,丹下 悦子,久保田 智子,増永 結子,南畝 晋平,藤尾 慈,東 純一,日本禁煙学会学術総会プログラム・抄録集,(一社)日本禁煙学会,Vol. 3回,p. 58-58,2008年08月
  • Enhancement of proteasome-linked TonEBP/NFAT5 degradation in cardiomyocytes exposed to doxorubicin,Takashy Ito,Yasushi Fujio,Junichi Azuma,FASEB JOURNAL,FEDERATION AMER SOC EXP BIOL,Vol. 22,2008年04月,研究発表ペーパー・要旨(国際会議)
  • Carbacycline induces CPT-1 in cardiomyocytes via PPAR delta, independent of the IP receptor signaling pathway,Tadashi Kuroda,Keiko Yamauchi-Takihara,Hisao Hirota,Yasushi Fujio,Masatsugu Hori,JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY,ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD,Vol. 44,No. 2,p. 449-449,2008年02月,研究発表ペーパー・要旨(国際会議)
  • Thrombospondin 1 polymorphism (Thr523Ala) is associated with the response to beta-blockers in the patients with dilated cardiomyopathy,Shinpei Nonen,Yukako Ueno,Hiroshi Okamoto,Yasushi Fujio,Yasuhiko Takemoto,Minoru Yoshiyama,Fumio Terasaki,Kaoru Otsuka,Hiroshi Iwao,Junichi Azuma,YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN,PHARMACEUTICAL SOC JAPAN,Vol. 128,p. 83-83,2008年,研究発表ペーパー・要旨(国際会議)
  • Ablation of taurine transporter gene impaired the balance of protein synthesis and proteolysis in skeletal muscles,Mika Takai,Takashi Ito,Yasushi Kimura,Yoriko Uozumi,Takahito Ito,Haruaki Nobori,Karla Okada,Yasushi Fujio,Junichi Azuma,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 106,p. 83P-83P,2008年,研究発表ペーパー・要旨(国際会議)
  • 血小板減少症治療薬インターロイキン(IL)‐11を用いた心不全に対するサイトカイン療法II―慢性モデルを用いた検討―,藤尾慈,尾花理徳,有田惇之,山本泰弘,毛利朋美,岩倉智彦,早田望,端山明子,松田浩一,前田真貴子,東純一,臨床薬理,(一社)日本臨床薬理学会,Vol. 38,No. Supplement,p. S206-S206,2007年11月15日
  • 血小板減少症治療薬インターロイキン(IL)‐11を用いた心不全に対するサイトカイン療法I―急性モデルを用いた検討―,前田真貴子,有田惇之,尾花理徳,山本泰弘,毛利朋美,岩倉智彦,早田望,端山明子,松田浩一,藤尾慈,東純一,臨床薬理,(一社)日本臨床薬理学会,Vol. 38,No. Supplement,p. S205-S205,2007年11月15日
  • Gab family scaffolding adaptor proteins are essential for postnatal maintenance of cardiac function via neuregulin-1/ErbB signaling,Yoshikazu Nakaoka,Atsunori Kamiya,Takashi Minami,Hirofumi Sawa,Yasushi Fujio,Tatsuya Koyama,Hisao Hirota,Keiko Yamauchi-Takihara,Kinya Otsu,Masatsugu Hori,Toshio Hirano,Naoki Mochizuki,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 116,No. 16,p. 5-5,2007年10月,研究発表ペーパー・要旨(国際会議)
  • 科学的根拠に基づいた禁煙支援に向けて ニコチン性アセチルコリン受容体α4サブユニット(CHRNA4)多型のニコチン依存性に及ぼす影響,東 純一,前田 真貴子,植木 理紗,谷口 智子,船本 全信,蓮沼 智子,三浦 源太,山本 明子,丹下 悦子,久保田 智子,増永 結子,福田 剛史,南畝 晋平,藤尾 慈,日本禁煙学会学術総会プログラム・抄録集,(一社)日本禁煙学会,Vol. 2回,p. 51-51,2007年08月
  • The social acceptance of the clinical application of pharmacogenomics in Japan,Yasushi Fujio,Mieko Tamaoki,Kiichiro Tsutani,Junichi Azuma,Hiroshi Watanabe,Japanese Journal of Clinical Pharmacology and Therapeutics,Vol. 38,No. 4,p. 225-230,2007年07月,書評論文,書評,文献紹介等
  • 科学的根拠に基づいた禁煙支援に向けて~ニコチン性アセチルコリン受容体α4サブユニット(CHRNA4)多型はニコチン依存性に影響を及ぼす~,増永結子,植木理紗,谷口智子,船本全信,三浦源太,蓮沼智子,山本明子,丹下悦子,久保田智子,前田真貴子,福田剛史,藤尾慈,東純一,医療薬学フォーラム講演要旨集,Vol. 15th,2007年07月
  • 血小板減少症治療薬インターロイキン11(IL‐11)の心不全発症予防薬としての可能性と研究意義,前田真貴子,有田敦之,尾花理徳,山本泰弘,毛利友美,岩倉智彦,松田浩一,端山明子,山下朋美,藤尾慈,東純一,医療薬学フォーラム講演要旨集,Vol. 15th,2007年07月
  • BMP2-Smads signal protects cardiomyocytes from ischemia-reperfusion injury through the induction of beta-catenin,Mitsuru Masaki,Masahiro Izumi,Yasushi Fujio,Masatsugu Hori,Keiko Yamauchi-Takihara,JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY,ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD,Vol. 42,p. S195-S196,2007年06月,研究発表ペーパー・要旨(国際会議)
  • Carbacyclin induces CPT-1 in cardiac myocytes via PPAR delta, independent of the IP receptor signaling pathway,Tadashi Kuroda,Keiko Yamauchi-Takihara,Yasushi Fujio,Masatsugu Hori,JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY,ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD,Vol. 42,p. S48-S48,2007年06月,研究発表ペーパー・要旨(国際会議)
  • A transcriptional factor tonicityresponse element-binding protein (TonEBP) mediates hypertonicity-induced cytochrome P450 2E1 (CYP2E1) upregulation in human hepatocytes,Koko Asakura,Takashi Ito,Katsuhiko Tougou,Tsuyoshi Fukuda,Ryuji Kubota,Yasushi Fujio,Junichi Azuma,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 103,p. 85P-85P,2007年,研究発表ペーパー・要旨(国際会議)
  • Taurine depletion leads to the impaired mitochondrial function and cardiomyopathy in mice,Takashi Ito,Yasushi Fujio,Yoriko Uozumi,Yasushi Kimura,Mika Takai,Junichi Azuma,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 103,p. 109P-109P,2007年,研究発表ペーパー・要旨(国際会議)
  • Disruption of taurine transporter gene results in the decrease of exercise capacity and skeletal muscle atrophy in mice.,Yasushi Kimura,Takashi Ito,Yoriko Uozumi,Mika Takai,Takahito Ito,Yasushi Fujio,Junichi Azuma,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 103,p. 105P-105P,2007年,研究発表ペーパー・要旨(国際会議)
  • Rac 1 activity is required for cardiac myocyte alignment in response to mechanical stress,Masako Yamane,Takahisa Matsuda,Takashi Ito,Yasushi Fujio,Kyoko Takahashi,Junichi Azuma,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 103,p. 98P-98P,2007年,研究発表ペーパー・要旨(国際会議)
  • Carbacyclin induces CPT-1 in cardiomyocytes via PPAR delta, independent of the IP receptor signaling pathway,Tadashi Kuroda,Keiko Yamauchi-Takihara,Yasushi Fujio,Masatsugu Hori,JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY,ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD,Vol. 41,No. 6,p. 1068-1068,2006年12月,研究発表ペーパー・要旨(国際会議)
  • Cross-talk between BMP 2 and leukemia inhibitory factor through ERK 1/2 and Smad1 in protection against doxorubicin-induced injury of cardiomyocytes,Mitsuru Masaki,Masahiro Izumi,Yasushi Fujio,Keiko Takihara,Masatsugu Hori,JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY,ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD,Vol. 41,No. 6,p. 1065-1065,2006年12月,研究発表ペーパー・要旨(国際会議)
  • 科学的根拠に基づいた禁煙支援に向けて~ニコチン性アセチルコリン受容体α4サブユニット(CHRNA4)多型のニコチン依存性に及ぼす影響~,植木理紗,谷口智子,丹下悦子,久保田智子,福田剛史,船本全信,前田真貴子,藤尾慈,東純一,臨床薬理,(一社)日本臨床薬理学会,Vol. 37,No. Supplement,p. S128-S229,2006年11月15日
  • 科学的根拠に基づいた禁煙支援に向けて ニコチン性アセチルコリン受容体α4サブユニット(CHRNA4)多型のニコチン依存性に及ぼす影響,植木 理紗,谷口 智子,丹下 悦子,久保田 智子,福田 剛史,船本 全信,前田 真貴子,藤尾 慈,東 純一,臨床薬理,(一社)日本臨床薬理学会,Vol. 37,No. Suppl.,p. S128-S128,2006年11月
  • Adrenoceptor alpha 1B and norepinephrine transporter polymorphisms are associated with the response to beta-blockers in patients with dilated cardiomyopathy,Hiroshi Okamoto,Shinpei Nonen,Yasushi Fujio,Yasuhiko Takemoto,Minoru Yoshiyama,Tomoyuki Hamaguchi,Yutaka Matsui,Junichi Yoshikawa,Akira Kitabatake,Junichi Azuma,JOURNAL OF CARDIAC FAILURE,CHURCHILL LIVINGSTONE INC MEDICAL PUBLISHERS,Vol. 12,No. 8,p. S172-S172,2006年10月,研究発表ペーパー・要旨(国際会議)
  • Disruption of Taurine transporter gene results in abnormal cardiac morphology associated with impairment of mitochondrial ultrastructure and function in mice,Takashi Ito,Yasushi Fujio,Yoriko Uozumi,Kyoko Takahashi,Junichi Azuma,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 114,No. 18,p. 101-101,2006年10月,研究発表ペーパー・要旨(国際会議)
  • Adrenoceptor alpha(1B) (G549A) and norepinephrine transporter (T-182C) polynnorphisms are associated with the response to beta-blockers in the patients with dilated cardiomyopathy,Hiroshi Okamoto,Shinpei Nonen,Yasushi Fujio,Yasuhiko Takemoto,Minoru Yoshiyama,Tomoyuki Hamaguchi,Yutaka Matsui,Junichi Yoshikawa,Akira Kitabatake,Junichi Azuma,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 114,No. 18,p. 443-443,2006年10月,研究発表ペーパー・要旨(国際会議)
  • 入賞 保険薬局薬剤師が薬学生の医療人教育に貢献するために解決すべき課題 (日本薬学会医療薬科学部会公募論文),前田 真貴子,藤尾 慈,上島 悦子,月刊薬事,じほう,Vol. 48,No. 11,p. 1799-1803,2006年10月
  • Impaired mitochondrial ultrastructure and metabolic function in cardiac and skeletal muscle in taurine-deficient mice,Takashi Ito,Yoriko Uozumi,Yasushi Fujio,Kyoko Takahashi,Junichi Azuma,CIRCULATION RESEARCH,LIPPINCOTT WILLIAMS & WILKINS,Vol. 99,No. 5,p. E25-E25,2006年09月,研究発表ペーパー・要旨(国際会議)
  • 保険調剤薬局における薬剤師職能について解決すべき課題,大風春乃,滝本桂子,大風幸一,中村真由美,矢野加奈子,徳野裕子,徳野晶子,京田和代,森あかね,佐藤千恵,黒田晶子,前田真貴子,藤尾慈,東純一,医療薬学フォーラム講演要旨集,Vol. 14th,2006年07月
  • 科学的根拠に基づいた禁煙支援に向けて~ニコチン性アセチルコリン受容体α4サブユニット(CHRNA4)多型のニコチン依存性に及ぼす影響~,植木理紗,谷口智子,丹下悦子,久保田智子,福田剛史,船本全信,前田真貴子,藤尾慈,東純一,医療薬学フォーラム講演要旨集,Vol. 14th,2006年07月
  • 薬学部6年制導入に向けての薬剤師の意識調査,黒田晶子,大風春乃,大風幸一,前田真貴子,藤尾慈,東純一,医療薬学フォーラム講演要旨集,Vol. 14th,2006年07月
  • 「薬剤師の現状と将来に対する意識調査」から見えてきたこと,前田真貴子,大風春乃,大風幸一,藤尾慈,東純一,医療薬学フォーラム講演要旨集,Vol. 14th,2006年07月
  • Cardiac expression of mineralocorticoid receptor contributes to cardiac remodeling after myocardial infarction,Y Yamamoto,Y Oshima,T Ito,ZG Qiu,T Mohri,Y Uozumi,Y Kimura,R Kimura,K Takahashi,Y Fujio,J Azuma,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 100,p. 86P-86P,2006年,研究発表ペーパー・要旨(国際会議)
  • Taurine/taurine transporter system contributes to cytoprotection and normal development in skeletal muscles,Y Uozumi,T Ito,Y Hoshino,T Mohri,Y Kimura,M Takai,K Takahashi,Y Fujio,J Azuma,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 100,p. 112P-112P,2006年,研究発表ペーパー・要旨(国際会議)
  • Doxorubicin induces atrogin-1, a muscle-specific ubiquitin ligase through FOXO pathway,Y Hoshino,Y Fujio,T Ito,T Mohri,Y Uozumi,J Azuma,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 100,p. 111P-111P,2006年,研究発表ペーパー・要旨(国際会議)
  • Leukemia inhibitory factor induces endothelial differentiation in cardiac Sca-1+stem cells,T Mohri,Y Fujio,M Maeda,T Ito,T Iwakura,Y Oshima,Y Uozumi,Y Yamamoto,J Azuma,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 100,p. 73P-73P,2006年,研究発表ペーパー・要旨(国際会議)
  • Hyperhomocyseinemia (Hcy) increases the expression of inflammatory cytokines in retina of streptozocine (STZ)-induced diabetic rats,M Maeda,Y Fujio,J Kim,T Ito,J Azuma,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 100,p. 100P-100P,2006年,研究発表ペーパー・要旨(国際会議)
  • The degradation of NFAT5 is induced by doxorubicin and impairs cell viability in cardiomyocytes,T Ito,Y Uozumi,Y Hoshino,M Takai,M Maeda,Y Yamamoto,T Mohri,Y Kimura,Y Fujio,J Azuma,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 100,p. 102P-102P,2006年,研究発表ペーパー・要旨(国際会議)
  • Transcription factor NFAT5 is necessary for regulation of taurine transporter and cell survival in cardiomyocytes,T Ito,Y Fujio,T Matsuda,K Takahashi,J Azuma,JOURNAL OF CARDIAC FAILURE,CHURCHILL LIVINGSTONE INC MEDICAL PUBLISHERS,Vol. 11,No. 9,p. S279-S279,2005年12月,研究発表ペーパー・要旨(国際会議)
  • 喫煙習慣と遺伝的要因の探索~依存や離脱に及ぼすセロトニンの影響~,丹下悦子,久保田智子,谷口智子,船本全信,藤尾慈,福田剛史,植木理紗,前田真貴子,南畝晋平,原英記,東純一,臨床薬理,(一社)日本臨床薬理学会,Vol. 36,No. Supplement,p. S184-S184,2005年11月15日
  • CYP246 polymorphisms have an impact on nicotine dependence and influence withdrawal symptoms in smoking cessation,Y Fujio,T Kubota,C Nakajima-Taniguchi,M Funamoto,M Maeda,E Tange,R Ueki,T Fukuda,H Hara,J Azuma,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 112,No. 17,p. U896-U896,2005年10月,研究発表ペーパー・要旨(国際会議)
  • 科学的根拠に基づく,禁煙支援への介助‐CYP2A6遺伝子多型の喫煙習慣及び禁煙に及ぼす影響‐,前田真貴子,久保田智子,福田剛史,丹下悦子,植木理沙,川島一剛,谷口智子,船本全信,原英記,藤尾慈,東純一,医療薬学フォーラム講演要旨集,Vol. 13th,2005年07月
  • Loss of body weight in mice lacking of taurine transporter,T Ito,Y Fujio,S Muraoka,T Fukuda,T Matsuda,Y Uozumi,Y Kimura,K Ueki,K Momiyama,K Takahashi,J Azuma,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 97,p. 250P-250P,2005年,研究発表ペーパー・要旨(国際会議)
  • Temperature elevation of coronary artery plaques is associated with the upregulation of the proinflammatory cytokine, IL-1 beta,J Kim,M Maeda,Y Fujio,S Negoro,K Kunisada,J Azuma,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 97,p. 98P-98P,2005年,研究発表ペーパー・要旨(国際会議)
  • Protective effect of taurine against doxorubicin-induced cardiotoxicity in mice,S Muraoka,T Ito,Y Fujio,Y Uozumi,Y Kimura,T Matsuda,K Takahashi,J Azuma,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 97,p. 193P-193P,2005年,研究発表ペーパー・要旨(国際会議)
  • Taurine transporter is transcriptionally regulated through MEF2 during skeletal muscle differentiation,Y Uozumi,Y Fujio,T Ito,S Muraoka,T Matsuda,T Nariai,T Mohri,Y Kimura,K Takahashi,J Azuma,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 97,p. 129P-129P,2005年,研究発表ペーパー・要旨(国際会議)
  • メチレンテトラヒドロ葉酸還元酵素の遺伝子多型と糖尿病網膜症および腎症との関係,前田真貴子,山本勇,西田真理,藤尾慈,元村卓嗣,五十嵐敢,阪本吉広,岡本紀夫,福田全克,日本糖尿病眼学会誌,日本糖尿病眼学会,Vol. 9,p. 146-146,2004年08月28日
  • N-cadherin determined the localization of connexin 43 through Rho pathway in cardiac myocytes,T Matsuda,K Takahashi,T Nariai,T Ito,T Takatani,M Hirata,Y Fujio,J Azuma,JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY,ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD,Vol. 37,No. 1,p. 170-170,2004年07月,研究発表ペーパー・要旨(国際会議)
  • Protective mechanism of taurine on ischemia-induced apoptosis in cultured cardiomyocytes,K Takahashi,T Takatani,Y Uozumi,T Ito,T Matsuda,Y Fujio,SW Schaffer,J Azuma,JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY,ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD,Vol. 37,No. 1,p. 247-248,2004年07月,研究発表ペーパー・要旨(国際会議)
  • メチレンテトラヒドロ葉酸還元酵素(MTHFR)の遺伝子多型と糖尿病網膜症との関係,前田真貴子,山本勇,福田全克,西田真理,南畝晋平,五十嵐敢,元村卓嗣,藤尾慈,東純一,医療薬学フォーラム講演要旨集,Vol. 12th,2004年06月
  • Mechanical stretch in the early stage after cultivation is a determinant for cell orientation, leading to localization of Cx43 in cardiomyocytes,T Nariai,K Takahashi,T Matsuda,T Takatani,T Ito,M Hirata,Y Fujio,J Azuma,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 94,p. 151P-151P,2004年,研究発表ペーパー・要旨(国際会議)
  • Osmoregulation of taurine transporter mediated by TonE/TonEBP pathway as a cytoprotective response,T Ito,Y Fujio,M Hirata,T Takatani,T Matsuda,S Muraoka,K Takahashi,J Azuma,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 94,p. 124P-124P,2004年,研究発表ペーパー・要旨(国際会議)
  • STAT3 as a therapeutic target for heart failure,Y Fujio,J Azuma,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 94,p. 37P-37P,2004年,研究発表ペーパー・要旨(国際会議)
  • The mitochondrial apoptotic pathway is activated on an in vitro cell culture model of seal-induced cardiac ischemia,T Takatani,K Takahashi,Y Uozumi,T Ito,T Matsuda,Y Fujio,J Azuma,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 94,p. 153P-153P,2004年,研究発表ペーパー・要旨(国際会議)
  • Homocysteine contributed to angiogenesis through VEGF induction in vitro,M Maeda,Y Fujio,Yamamoto, I,J Azuma,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 94,p. 156P-156P,2004年,研究発表ペーパー・要旨(国際会議)
  • The aligned cardiomyocytes lead to the localization of Cx43 at the intercalated disk through N-cadherin/Rho pathway,T Matsuda,K Takahashi,T Nariai,T Ito,T Takatani,Y Fujio,J Azuma,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 94,p. 88P-88P,2004年,研究発表ペーパー・要旨(国際会議)
  • Taurine suppressed cardiac hypertrophy induced by endothelin-1 in rat neonatal cardiac myocytes,M Hirata,K Takahashi,T Ito,S Muraoka,T Takatani,T Matsuda,Y Fujio,J Azuma,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 94,p. 269P-269P,2004年,研究発表ペーパー・要旨(国際会議)
  • Interaction of Scaffolding/Docking protein Gab1 with tyrosine phosphatase SHP2 is involved in gp130-mediated activation of ERK5 and elongation of cardiomyocytes,Y Nakaoka,K Nishida,Y Fujio,M Izumi,K Terai,Y Oshima,S Sugiyama,S Matsuda,S Koyasu,K Yamauchi-Takihara,Kawase, I,T Hirano,H Hirota,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 108,No. 17,p. 52-52,2003年10月,研究発表ペーパー・要旨(国際会議)
  • Pioglitazoneは血しょう型Platelet Activating Factor-Acetylhydrolaseを誘導する事で抗動脈硬化作用を示す,角田ちぬよ,藤尾慈,藤津純子,前田真貴子,笠山宗正,山本勇,東純一,日本動脈硬化学会総会プログラム・抄録集,Vol. 35th,2003年09月01日
  • No association between the MTHFR gene polymorphism and diabetic retinopathy in type 2 diabetic patients without overt nephropathy [10],Keiji Yoshioka,Toshihide Yoshida,Yasuto Takakura,Akinori Kogure,Tsunekazu Umekawa,Hitoshi Toda,Toshikazu Yoshikawa,Makiko Maeda,Isamu Yamamoto,Masakatsu Fukuda,Mari Nishida,Junko Fujitsu,Shinpei Nonen,Tsuyoshi Igarashi,Takashi Motomura,Makiko Inaba,Yasushi Fujio,Junichi Azuma,Diabetes Care,Vol. 26,No. 6,p. 1947-1948,2003年06月01日,速報,短報,研究ノート等(学術雑誌)
  • 脂質代謝に関与する脂肪酸活性化酵素(acyl‐CoA synthetase:ACS)のピオグリタゾンによる誘導作用,岩田悦子,山本勇,福円修一,前田真貴子,松永憲和,角田ちぬよ,高橋京子,藤尾慈,東純一,日本薬学会年会要旨集,(公社)日本薬学会,Vol. 123rd,No. 4,p. 32-32,2003年03月05日
  • メチレンテトラヒドロ葉酸還元酵素(MTHFR)の遺伝子多型と糖尿病網膜症との関係,前田 真貴子,山本 勇,福田 全克,西田 真理,五十嵐 敢,元村 卓嗣,稲葉 真希子,藤尾 慈,東 純一,日本眼科紀要 = Folia ophthalmologica Japonica,日本眼科紀要会,Vol. 54,No. 1,p. 11-15,2003年01月28日
  • N-cadherin is related to the oriented responses of cardiomyocytes by mechanical stretch.,T Matsuda,K Takahashi,T Itoh,T Takatani,T Nariai,Y Fujio,J Azuma,JOURNAL OF PHARMACOLOGICAL SCIENCES,JAPANESE PHARMACOLOGICAL SOC,Vol. 91,p. 104P-104P,2003年,研究発表ペーパー・要旨(国際会議)
  • Overexpression of Bcl-xL inhibits doxorubicin-induced cell death but fails to control cardiac-specific gene downregulation in cardiac myocytes,K Kunisada,K Yamauchi-Takihara,E Tone,Y Fujio,Y Oshima,Y Nakaoka,H Hirota,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 106,No. 19,p. 236-236,2002年11月,研究発表ペーパー・要旨(国際会議)
  • Cardiac-specific activation of signal transducer and activator of transcription 3 (STAT3) prevents myocardial damage induced by ischemia/reperfusion,Y Oshima,Y Fujio,S Sugiyama,M Izumi,Y Nakaoka,T Osugi,H Hirota,K Yamauchi-Takihara,T Kishimoto,Kawase, I,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 106,No. 19,p. 193-193,2002年11月,研究発表ペーパー・要旨(国際会議)
  • Loss of STAT3-dependent pathway in cardiac cell is a critical event in the onset of myocardial fibrosis,H Hirota,Y Nakaoka,M Izumi,Y Oshima,Y Fujio,K Yamauchi-Takihara,Kawase, I,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 106,No. 19,p. 160-160,2002年11月,研究発表ペーパー・要旨(国際会議)
  • Activation of Gp130 transduces cardiac hypertrophy through the interaction of scaffolding protein Gab1 and tyrosine phosphatase SHP2,Y Nakaoka,K Nishida,Y Fujio,M Izumi,Y Oshima,K Yamauchi-Takihara,T Hirano,H Hirota,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 106,No. 19,p. 259-259,2002年11月,研究発表ペーパー・要旨(国際会議)
  • Targeted disruption of Gab1 gene leads to developmental abnormalities in heart,Y Nakaoka,K Nishida,M Izumi,Y Fujio,K Yamauchi-Takihara,T Hirano,H Hirota,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 106,No. 19,p. 286-286,2002年11月,研究発表ペーパー・要旨(国際会議)
  • Cardiac specific activation of Stat3 promotes the vascular formation in the heart,Y Fujio,Y Oshima,M Funamoto,S Negoro,K Kunisada,M Izumi,Y Nakaoka,T Osugi,H Hirota,K Yamauchi-Takihara,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 104,No. 17,p. 221-221,2001年10月,研究発表ペーパー・要旨(国際会議)
  • Akt1 mediates the onset of vascular smooth muscle cell polyploidization and hypertrophy,ML Hixon,G Muro-Cacho,MW Wagner,CA Obejero-Paz,E Millie,Y Fujio,Y Kureishi,T Hassold,K Walsh,A Gualberto,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 102,No. 18,p. 57-57,2000年10月,研究発表ペーパー・要旨(国際会議)
  • Akt1/PKB signaling in endothelial cells is sufficient for blood vessel growth in ischemic hindlimb,ZY Luo,Y Kureishi,Y Fujio,K Walsh,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 102,No. 18,p. 44-44,2000年10月,研究発表ペーパー・要旨(国際会議)
  • Activation of GP130-mediated signal protects oxidative stress-induced cardiomyocyte damage by upregulation of antioxidant enzymes,S Negoro,K Kunisada,E Tone,Y Fujio,M Funamoto,M Izumi,H Hirota,K Yamauchi-Takihara,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 102,No. 18,p. 85-85,2000年10月,研究発表ペーパー・要旨(国際会議)
  • Akt/protein kinase B regulates flow-dependent activation of cJun N-terminal kinase by producing nitric oxide from endothelial nitric oxide synthase,YM Go,Y Boo,H Park,MC Maland,R Patel,Darley-Usmar, V,KA Pritchard,Y Fujio,K Walsh,H Jo,FASEB JOURNAL,FEDERATION AMER SOC EXP BIOL,Vol. 14,No. 4,p. A403-A403,2000年03月,研究発表ペーパー・要旨(国際会議)
  • The protein kinase Akt regulates endothelium-dependent vasomotion in vivo,ZY Luo,Y Fujio,D Fulton,WC Sessa,K Walsh,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 100,No. 18,p. 339-339,1999年11月,研究発表ペーパー・要旨(国際会議)
  • Akt mediates IGF-1 cytoprotection of cardiomyocytes in vitro and protects against ischemia-reperfusion injury in mouse heart,Y Fujio,RN Kitsis,K Walsh,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 100,No. 18,p. 9-9,1999年11月,研究発表ペーパー・要旨(国際会議)
  • Akt mediates cytoprotection of endothelial cells by anchorage-dependent survival signals,Y Fujio,K Walsh,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 100,No. 18,p. 703-704,1999年11月,研究発表ペーパー・要旨(国際会議)
  • Regulation of endothelium-derived nitric oxide production by the protein kinase Akt (vol 399, pg 597, 1999),D Fulton,JP Gratton,TJ McCabe,J Fontana,Y Fujio,K Walsh,TF Franke,A Papapetropoulos,WC Sessa,NATURE,MACMILLAN MAGAZINES LTD,Vol. 400,No. 6746,p. 792-792,1999年08月
  • Akt mediates the cell survival effects of vascular endothelial growth factor.,Y Fujio,T Mano,K Walsh,CIRCULATION,LIPPINCOTT WILLIAMS & WILKINS,Vol. 98,No. 17,p. 463-463,1998年10月,研究発表ペーパー・要旨(国際会議)
  • Adenovirus-mediated gene transfer of STAT3 to cardiac myocytes transduces hypertrophic signals without affecting MAP kinase activity,K Kunisada,E Tone,S Negoro,Y Fujio,K YamauchiTakihara,T Kishimoto,CIRCULATION,AMER HEART ASSOC,Vol. 96,No. 8,p. 3116-3116,1997年10月,研究発表ペーパー・要旨(国際会議)
  • Activation of gp130 transduces cytoprotective signals in cardiac myocytes,K YamauchiTakihara,Y Fujio,K Kunisada,H Matsui,T Kishimoto,CIRCULATION,AMER HEART ASSOC,Vol. 96,No. 8,p. 2370-2370,1997年10月,研究発表ペーパー・要旨(国際会議)
  • Phosphatidylinositol 3-kinase mediates gp130 dependent hypertrophic signals in cardiac myocyte,H Oh,Y Fujio,K Kunisada,H Matsui,S Hishinuma,K YamauchiTakihara,T Kishimoto,CIRCULATION,AMER HEART ASSOC,Vol. 96,No. 8,p. 3110-3110,1997年10月,研究発表ペーパー・要旨(国際会議)
  • Hypoxic stress induces nuclear factor (NF)-kappa B and NF-IL6 transcription factors in cardiac myocytes,H Matsui,Y Fujio,K YamauchiTakihara,T Kishimoto,CIRCULATION,AMER HEART ASSOC,Vol. 96,No. 8,p. 1329-1329,1997年10月,研究発表ペーパー・要旨(国際会議)
  • Leukemia inhibitory factor induces hypertrophic response through gp130 in murine cardiac myocyte,H Matsui,Y Fujio,K Kunisada,H Hirota,K YamauchiTakihara,T Kishimoto,CIRCULATION,AMER HEART ASSOC,Vol. 94,No. 8,p. 3104-3104,1996年10月,研究発表ペーパー・要旨(国際会議)
  • Targeted disruption of gp130, a common signal transducer for the interleukin 6 family of cytokines, leads to myocardial disorder,H Hirota,K Yoshida,S Hishinuma,H Oh,Y Fujio,H Matsui,K Kunisada,K YamauchiTakihara,T Taga,T Kishimoto,CIRCULATION,AMER HEART ASSOC,Vol. 94,No. 8,p. 1739-1739,1996年10月,研究発表ペーパー・要旨(国際会議)
  • Activation of gp130 induces Bcl-xL in cardiac myocytes,Y Fujio,K Kunisada,H Hirota,H Matsui,K YamauchiTakihara,T Kishimoto,CIRCULATION,AMER HEART ASSOC,Vol. 94,No. 8,p. 1637-1637,1996年10月,研究発表ペーパー・要旨(国際会議)
  • Activation of JAK-STAT and MAP kinase by leukemia inhibitory factor in cardiac myocyte,K Kunisada,H Hirota,Y Fujio,H Matsui,K YamauchiTakihara,T Kishimoto,CIRCULATION,AMER HEART ASSOC,Vol. 94,No. 8,p. 2360-2360,1996年10月,研究発表ペーパー・要旨(国際会議)
  • MYOCARDIAL HYPERTROPHY CAUSED IN MICE BY CONTINUOUS ACTIVATION OF GP130, A SIGNAL-TRANSDUCING RECEPTOR COMPONENT FOR IL-6-RELATED CYTOKINES,H HIROTA,Y FUJIO,H MATSUI,K KUNISADA,Y IHARA,K YTAKIHARA,K YOSHIDA,T TAGA,T KISHIMOTO,CIRCULATION,AMER HEART ASSOC,Vol. 92,No. 8,p. 1139-1139,1995年10月,研究発表ペーパー・要旨(国際会議)
  • LEUKEMIA INHIBITORY FACTOR SIGNALING TO THE NUCLEUS THROUGH JAK-STAT PATHWAY IN MURINE HEART,K KUNISADA,H HIROTA,Y FUJIO,H MATSUI,Y IHARA,K YTAKIHARA,T KISHIMOTO,CIRCULATION,AMER HEART ASSOC,Vol. 92,No. 8,p. 2725-2725,1995年10月,研究発表ペーパー・要旨(国際会議)
  • CA-2+ REGULATION OF CALSPECTIN (FODRIN) ACTIN INTERACTION - COMPARISON WITH ERYTHROCYTE SPECTRIN-ACTIN INTERACTION,T TANAKA,K KANDA,Y FUJIO,K SOBUE,NEUROCHEMICAL RESEARCH,PLENUM PUBL CORP,Vol. 13,No. 3,p. 260-260,1988年03月,研究発表ペーパー・要旨(国際会議)
  • CA2+ REGULATION OF ADRENAL-MEDULLARY ACTOMYOSIN,T TANAKA,K KANDA,K ITOH,Y FUJIO,K SOBUE,S KAKIUCHI,NEUROCHEMICAL RESEARCH,PLENUM PUBL CORP,Vol. 11,No. 12,p. 1791-1791,1986年12月,研究発表ペーパー・要旨(国際会議)