EN

基本情報

研究

社会活動

その他の活動

深瀬 浩一

Koichi Fukase

理学研究科 化学専攻,教授

keyword 有機合成,糖質化学,天然物有機化学

学歴

  • ~ 1987年,大阪大学,理学研究科,有機化学
  • ~ 1987年,大阪大学
  • ~ 1982年,大阪大学,理学部
  • ~ 1982年,大阪大学

経歴

  • 1998年 ~ 2004年,大阪大学,大学院理学研究科,助教授
  • 1996年 ~ 1998年,大阪大学講師
  • 1996年 ~ 1998年,大阪大学
  • 1988年 ~ 1996年,大阪大学助手
  • 1988年 ~ 1996年,Osaka University, Research Associate
  • 1987年 ~ 1988年,日本学術振興会特別研究員
  • 1987年 ~ 1988年,Postdoctral Fellow of JSPS

研究内容・専門分野

  • ナノテク・材料,生体化学
  • ナノテク・材料,有機合成化学
  • ライフサイエンス,生物有機化学
  • ナノテク・材料,構造有機化学、物理有機化学
  • ナノテク・材料,生物分子化学

所属学会

  • フロンティア生命化学研究会
  • International Society for Combinatorial Science
  • 天然物化学談話会
  • 日本化学会・生体機能関連化学部会
  • 天然有機化合物討論会
  • International Endotoxin and Innate Immunity Society
  • 日本ケミカルバイオロジー研究会
  • 日本細菌学会
  • Combinatorial Chemistry研究会
  • 日本ペプチド学会
  • 日本糖質学会
  • 有機合成化学協会
  • 日本化学会
  • International Society for Combinatorial Science
  • Japanease society for chemical biology
  • The Japanese Combinatorial Chemistry Focus Group
  • The Japanese Society of Carbohydrate Research
  • The Japaneses Peptide Society
  • American Chemical Society

論文

  • Electrocyclization-Based Labeling Allows Efficient In Vivo Imaging of Cellular Trafficking,Katsunori Tanaka,Kaori Minami,Tsuyoshi Tahara,Yohei Fujii,Eric R. O. Siwu,Satoshi Nozaki,Hirotaka Onoe,Satomi Yokoi,Koichi Koyama,Yasuyoshi Watanabe,Koichi Fukase,CHEMMEDCHEM,WILEY-V C H VERLAG GMBH,Vol. 5,No. 6,p. 841-845,2010年06月,研究論文(学術雑誌)
  • Synthesis of [<sup>211</sup>At]4-astato-L-phenylalanine by dihydroxyboryl-astatine substitution reaction in aqueous solution,Yoshifumi Shirakami,Tadashi Watabe,Honoka Obata,Kazuko Kaneda,Kazuhiro Ooe,Yuwei Liu,Takahiro Teramoto,Atsushi Toyoshima,Atsushi Shinohara,Eku Shimosegawa,Jun Hatazawa,Koichi Fukase,Scientific Reports,Vol. 11,No. 1,2021年12月,研究論文(学術雑誌)
  • Lipopolysaccharide from Gut-Associated Lymphoid-Tissue-Resident Alcaligenes faecalis: Complete Structure Determination and Chemical Synthesis of Its Lipid A,Atsushi Shimoyama,Flaviana Di Lorenzo,Haruki Yamaura,Keisuke Mizote,Angelo Palmigiano,Molly D. Pither,Immacolata Speciale,Tomoya Uto,Seiji Masui,Luisa Sturiale,Domenico Garozzo,Koji Hosomi,Naoko Shibata,Kazuya Kabayama,Yukari Fujimoto,Alba Silipo,Jun Kunisawa,Hiroshi Kiyono,Antonio Molinaro,Koichi Fukase,ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,WILEY-V C H VERLAG GMBH,Vol. 60,No. 18,p. 10023-10031,2021年04月,研究論文(学術雑誌)
  • Synthesis of cyclotetrapeptide analogues of c-PLAI and evaluation of their antimicrobial properties,Rani Maharani,Orin Inggriani Napitupulu,Jelang M. Dirgantara,Ace Tatang Hidayat,Dadan Sumiarsa,Desi Harneti,Nurlelasari,Unang Supratman,Koichi Fukase,ROYAL SOCIETY OPEN SCIENCE,ROYAL SOC,Vol. 8,No. 3,2021年03月,研究論文(学術雑誌)
  • alpha-Emitting cancer therapy using At-211-AAMT targeting LAT1,Kazuko Kaneda-Nakashima,ZiJian Zhang,Yoshiyuki Manabe,Atsushi Shimoyama,Kazuya Kabayama,Tadashi Watabe,Yoshikatsu Kanai,Kazuhiro Ooe,Atsushi Toyoshima,Yoshifumi Shirakami,Takashi Yoshimura,Mitsuhiro Fukuda,Jun Hatazawa,Takashi Nakano,Koichi Fukase,Atsushi Shinohara,CANCER SCIENCE,WILEY,Vol. 112,No. 3,p. 1132-1140,2021年03月,研究論文(学術雑誌)
  • Behavior of glycolylated sialoglycans in the binding pockets of murine and human CD22,Cristina Di Carluccio,Rosa Ester Forgione,Marco Montefiori,Monica Civera,Sara Sattin,Giovanni Smaldone,K. Fukase,Y. Manabe,Paul R. Crocker,Antonio Molinaro,Roberta Marchetti,Alba Silipo,iScience,Vol. 24,No. 1,2021年01月22日,研究論文(学術雑誌)
  • Synthesis of ABO blood group antigens and functional glycan display on the cell surface,Masato Tsutsui,Yoshiyuki Manabe,Kazuya Kabayama,Koichi Fukase,ARKIVOC,ARKAT USA INC,p. 168-185,2021年,研究論文(学術雑誌)
  • Practical synthesis of 1-substituted 5-aminopyrazolo[4,3-d]pyrimidin-7-ones using intramolecular friedel-crafts type cyclization and its application to the synthesis of pharmaceutically active compounds,Takashi Goi,Tetsuji Matsudaira,Koichi Fukase,Heterocycles,Vol. 102,No. 1,p. 69-80,2021年,研究論文(学術雑誌)
  • Concise and Reliable Syntheses of Glycodendrimers via Self-Activating Click Chemistry: A Robust Strategy for Mimicking Multivalent Glycan-Pathogen Interactions,Kindi Farabi,Yoshiyuki Manabe,Hiroaki Ichikawa,Shuto Miyake,Masato Tsutsui,Kazuya Kabayama,Toshiyuki Yamaji,Katsunori Tanaka,Shang-Cheng Hung,Koichi Fukase,JOURNAL OF ORGANIC CHEMISTRY,AMER CHEMICAL SOC,Vol. 85,No. 24,p. 16014-16023,2020年12月,研究論文(学術雑誌)
  • Temporal analysis of localization and trafficking of glycolipids,Kenta Arai,Yoshimi Kanie,Osamu Kanie,Koichi Fukase,Kazuya Kabayama,BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,ACADEMIC PRESS INC ELSEVIER SCIENCE,Vol. 532,No. 1,p. 19-24,2020年10月,研究論文(学術雑誌)
  • Lymphoid Tissue-ResidentAlcaligenesEstablish an Intracellular Symbiotic Environment by Creating a Unique Energy Shift in Dendritic Cells,Koji Hosomi,Naoko Shibata,Atsushi Shimoyama,Tomoya Uto,Takahiro Nagatake,Yoko Tojima,Tomomi Nishino,Haruko Takeyama,Koichi Fukase,Hiroshi Kiyono,Jun Kunisawa,FRONTIERS IN MICROBIOLOGY,FRONTIERS MEDIA SA,Vol. 11,p. 561005-561005,2020年09月,研究論文(学術雑誌)
  • Total Syntheses of C60-and C100-Dolichols,Kohtaro Hirao,Risako Ono,Yoshiyuki Manabe,Seiji Masui,Haruyuki Atomi,Koichi Fukase,JOURNAL OF ORGANIC CHEMISTRY,AMER CHEMICAL SOC,Vol. 85,No. 17,p. 11549-11559,2020年09月,研究論文(学術雑誌)
  • Adjuvant Activity of Synthetic Lipid A of Alcaligenes, a Gut-Associated Lymphoid Tissue-Resident Commensal Bacterium, to Augment Antigen-Specific IgG and Th17 Responses in Systemic Vaccine,Yunru Wang,Koji Hosomi,Atsushi Shimoyama,Ken Yoshii,Haruki Yamaura,Takahiro Nagatake,Tomomi Nishino,Hiroshi Kiyono,Koichi Fukase,Jun Kunisawa,VACCINES,MDPI,Vol. 8,No. 3,p. 1-12,2020年09月,研究論文(学術雑誌)
  • Immunological Evaluation of Co-Assembling a Lipidated Peptide Antigen and Lipophilic Adjuvants: Self-Adjuvanting Anti-Breast-Cancer Vaccine Candidates,Taku Aiga,Yoshiyuki Manabe,Keita Ito,Tsung-Che Chang,Kazuya Kabayama,Shino Ohshima,Yoshie Kametani,Ayane Miura,Hiroto Furukawa,Hiroshi Inaba,Kazunori Matsuura,Koichi Fukase,ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,WILEY-V C H VERLAG GMBH,Vol. 59,No. 40,p. 17705-17711,2020年09月,研究論文(学術雑誌)
  • Unveiling Molecular Recognition of Sialoglycans by Human Siglec-10 (vol 23, 101231, 2020),Rosa Ester Forgione,Cristina Di Carluccio,Juan Guzman-Caldentey,Rosa Gaglione,Filomena Battista,Fabrizio Chiodo,Yoshiyuki Manabe,Angela Arciello,Pompea Del Vecchio,Koichi Fukase,Antonio Molinaro,Sonsoles Martin-Santamaria,Paul R. Crocker,Roberta Marchetti,Alba Silipo,ISCIENCE,CELL PRESS,Vol. 23,No. 8,p. 101401-101401,2020年08月,研究論文(学術雑誌)
  • Chemically SynthesizedAlcaligenesLipid A Shows a Potent and Safe Nasal Vaccine Adjuvant Activity for the Induction ofStreptococcuspneumoniae-Specific IgA and Th17 Mediated Protective Immunity,Ken Yoshii,Koji Hosomi,Atsushi Shimoyama,Yunru Wang,Haruki Yamaura,Takahiro Nagatake,Hidehiko Suzuki,Huangwenxian Lan,Hiroshi Kiyono,Koichi Fukase,Jun Kunisawa,MICROORGANISMS,MDPI,Vol. 8,No. 8,p. 1-20,2020年08月,研究論文(学術雑誌)
  • Pyrazolo[4,3-d]pyrimidine Derivatives as a Novel Hypoxia-Inducible Factor Prolyl Hydroxylase Domain Inhibitor for the Treatment of Anemia,Takashi Goi,Tatsuo Nakajima,Yoshiyuki Komatsu,Atsushi Kawata,Shuhei Yamakoshi,Okimasa Okada,Masakatsu Sugahara,Asami Umeda,Yoko Takada,Jun Murakami,Rikiya Ohashi,Tomoko Watanabe,Koichi Fukase,ACS MEDICINAL CHEMISTRY LETTERS,AMER CHEMICAL SOC,Vol. 11,No. 7,p. 1416-1420,2020年07月,研究論文(学術雑誌)
  • Homeostatic and pathogenic roles of GM3 ganglioside molecular species in TLR4 signaling in obesity,Hirotaka Kanoh,Takahiro Nitta,Shinji Go,Kei ichiro Inamori,Lucas Veillon,Wataru Nihei,Mayu Fujii,Kazuya Kabayama,Atsushi Shimoyama,Koichi Fukase,Umeharu Ohto,Toshiyuki Shimizu,Taku Watanabe,Hiroki Shindo,Sorama Aoki,Kenichi Sato,Mika Nagasaki,Yutaka Yatomi,Naoko Komura,Hiromune Ando,Hideharu Ishida,Makoto Kiso,Yoshihiro Natori,Yuichi Yoshimura,Asia Zonca,Anna Cattaneo,Marilena Letizia,Maria Ciampa,Laura Mauri,Alessandro Prinetti,Sandro Sonnino,Akemi Suzuki,Jin ichi Inokuchi,EMBO Journal,WILEY,Vol. 39,No. 12,2020年06月17日,研究論文(学術雑誌)
  • Unveiling Molecular Recognition of Sialoglycans by Human Siglec-10,Rosa Ester Forgione,Cristina Di Carluccio,Juan Guzman-Caldentey,Rosa Gaglione,Filomena Battista,Fabrizio Chiodo,Yoshiyuki Manabe,Angela Arciello,Pompea Del Vecchio,Koichi Fukase,Antonio Molinaro,Sonsoles Martin-Santamaria,Paul R. Crocker,Roberta Marchetti,Alba Silipo,ISCIENCE,CELL PRESS,Vol. 23,No. 6,p. 101231-101231,2020年06月,研究論文(学術雑誌)
  • Middle Molecular and Conjugation Strategies for Development of Bioactive Middle Molecules,Yoshiyuki Manabe,Atushi Shimoyama,Kazuya Kabayama,Koichi Fukase,JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN,SOC SYNTHETIC ORGANIC CHEM JPN,Vol. 78,No. 5,p. 527-537,2020年05月,研究論文(学術雑誌)
  • Discrimination of cellular developmental states focusing on glycan transformation and membrane dynamics by using BODIPY-tagged lactosyl ceramides,Kenta Arai,Atsuko Ohtake,Shusaku Daikoku,Katsuhiko Suzuki,Yukishige Ito,Kazuya Kabayama,Koichi Fukase,Yoshimi Kanie,Osamu Kanie,ORGANIC & BIOMOLECULAR CHEMISTRY,ROYAL SOC CHEMISTRY,Vol. 18,No. 19,p. 3724-3733,2020年05月,研究論文(学術雑誌)
  • A Review of Cytotoxic Plants of the Indian Subcontinent and a Broad-Spectrum Analysis of Their Bioactive Compounds,Kishor Mazumder,Biswajit Biswas,Iqbal Mahmud Raja,Koichi Fukase,MOLECULES,MDPI,Vol. 25,No. 8,2020年04月
  • Efficient Synthesis of Antigenic Trisaccharides Containing N-Acetylglucosamine: Protection of NHAc as NAc2,Masato Tsutsui,Julinton Sianturi,Seiji Masui,Kento Tokunaga,Yoshiyuki Manabe,Koichi Fukase,EUROPEAN JOURNAL OF ORGANIC CHEMISTRY,WILEY-V C H VERLAG GMBH,Vol. 2020,No. 12,p. 1802-1810,2020年03月,研究論文(学術雑誌)
  • Deficiency of sphingomyelin synthase 2 prolongs survival by the inhibition of lymphoma infiltration through ICAM-1 reduction,Makoto Taniguchi,Yoshibumi Ueda,Michiko Matsushita,Shingo Nagaya,Chieko Hashizume,Kenta Arai,Kazuya Kabayama,Koichi Fukase,Ken Watanabe,Lusi Oka Wardhani,Kazuhiko Hayashi,Toshiro Okazaki,FASEB JOURNAL,WILEY,Vol. 34,No. 3,p. 3838-3854,2020年03月,研究論文(学術雑誌)
  • Efficient Synthesis of Marine Alkaloid Ageladine A and its Structural Modification for Exploring New Biological Activity,Takayuki Iwata,Koichi Fukase,Yoichi Nakao,Katsunori Tanaka,JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN,SOC SYNTHETIC ORGANIC CHEM JPN,Vol. 78,No. 1,p. 55-63,2020年01月,研究論文(学術雑誌)
  • Characterisation of the Dynamic Interactions between Complex N-Glycans and Human CD22,Cristina Di Carluccio,Enrique Crisman,Yoshiyuki Manabe,Rosa Ester Forgione,Alessandra Lacetera,Jussara Amato,Bruno Pagano,Antonio Randazzo,Angela Zampella,Rosa Lanzetta,Koichi Fukase,Antonio Molinaro,Paul R. Crocker,Sonsoles Martin-Santamaria,Roberta Marchetti,Alba Silipo,CHEMBIOCHEM,WILEY-V C H VERLAG GMBH,Vol. 21,No. 1-2,p. 129-140,2020年01月,研究論文(学術雑誌)
  • Structural basis for Glycan-receptor binding by mumps virus hemagglutinin-neuraminidase,Rosa Ester Forgione,Cristina Di Carluccio,Marie Kubota,Yoshiyuki Manabe,Koichi Fukase,Antonio Molinaro,Takao Hashiguchi,Roberta Marchetti,Alba Silipo,SCIENTIFIC REPORTS,NATURE PUBLISHING GROUP,Vol. 10,No. 1,p. 1589-1589,2020年01月,研究論文(学術雑誌)
  • Syntheses and Functional Studies of Self-Adjuvanting Anti-HER2 Cancer Vaccines,Qi Feng,Yoshiyuki Manabe,Kazuya Kabayama,Taku Aiga,Asuka Miyamoto,Shino Ohshima,Yoshie Kametani,Koichi Fukase,CHEMISTRY-AN ASIAN JOURNAL,WILEY-V C H VERLAG GMBH,Vol. 14,No. 23,p. 4268-4273,2019年12月,研究論文(学術雑誌)
  • The Core Fucose on an IgG Antibody is an Endogenous Ligand of Dectin-1,Yoshiyuki Manabe,Roberta Marchetti,Yohei Takakura,Masahiro Nagasaki,Wataru Nihei,Tomoyuki Takebe,Katsunori Tanaka,Kazuya Kabayama,Fabrizio Chiodo,Shinya Hanashima,Yoshihiro Kamada,Eiji Miyoshi,Hari Prasad Dulal,Yoshiki Yamaguchi,Yoshiyuki Adachi,Naohito Ohno,Hiroshi Tanaka,Alba Silipo,Koichi Fukase,Antonio Molinaro,ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,WILEY-V C H VERLAG GMBH,Vol. 58,No. 51,p. 18697-18702,2019年12月,研究論文(学術雑誌)
  • Synthesis of Cage-Shaped Aluminum Aryloxides: Efficient Lewis Acid Catalyst for Stereoselective Glycosylation Driven by Flexible Shift of Four- to Five-Coordination,Daiki Tanaka,Yuichiro Kadonaga,Yoshiyuki Manabe,Koichi Fukase,Shota Sasaya,Hikaru Maruyama,Sota Nishimura,Mayu Yanagihara,Akihito Konishi,Makoto Yasuda,JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,AMER CHEMICAL SOC,Vol. 141,No. 44,p. 17466-17471,2019年11月,研究論文(学術雑誌)
  • がん研究における女性研究者(第6回) がん細胞型アミノ酸トランスポーターを標的とした短寿命アルファ線核医学治療薬の開発(Women scientists in cancer research Investigation of novel drug for alpha-emitting nuclear medicine targeting to cancer specific amino acid transporter),兼田 加珠子,真鍋 良幸,下山 敦史,樺山 一哉,金井 好克,豊嶋 厚史,深瀬 浩一,篠原 厚,日本癌学会総会記事,日本癌学会,Vol. 78回,p. SS-3,2019年09月
  • beta-Selective Glycosylation by Using O-Aryl-Protected Glycosyl Donors,Yuji Otsuka,Toshihiro Yamamoto,Koichi Fukase,CHEMISTRY-AN ASIAN JOURNAL,WILEY-V C H VERLAG GMBH,Vol. 14,No. 15,p. 2719-2723,2019年08月,研究論文(学術雑誌)
  • Activities of the Consortium for Medicine, Chemistry, and Physics at Osaka University,K. Kabayama,K. Kaneda,A. Shinohara,Y. Shirakami,T. Watabe,Z. Zhang,A. Toyoshima,T. Yoshimura,Y. Manabe,A. Shimoyama,K. Fukase,Journal of Medical Imaging and Radiation Sciences,2019年03月
  • Kinetically Controlled Fischer Glycosidation under Flow Conditions: A New Method for Preparing Furanosides,Seiji Masui,Yoshiyuki Manabe,Kohtaro Hirao,Atsushi Shimoyama,Takahide Fukuyama,Ilhyong Ryu,Koichi Fukase,SYNLETT,GEORG THIEME VERLAG KG,Vol. 30,No. 4,p. 397-400,2019年03月,研究論文(学術雑誌)
  • Development of α-Gal-Antibody Conjugates to Increase Immune Response by Recruiting Natural Antibodies.,Sianturi J,Manabe Y,Li HS,Chiu LT,Chang TC,Tokunaga K,Kabayama K,Tanemura M,Takamatsu S,Miyoshi E,Hung SC,Fukase K,Angewandte Chemie (International ed. in English),Vol. 58,No. 14,p. 4526-4530,2019年03月,研究論文(学術雑誌)
  • Single-Step Per-O-Sulfonation of Sugar Oligomers with Concomitant 1,6-Anhydro Bridge Formation for Binding Fibroblast Growth Factors,Che-Jui Yeh,Chiao-Chu Ku,Wei-Chen Lin,Chiao-Yuan Fan,Medel Manuel L. Zulueta,Yoshiyuki Manabe,Koichi Fukase,Yaw-Kuen Li,Shang-Cheng Hung,CHEMBIOCHEM,WILEY-V C H VERLAG GMBH,Vol. 20,No. 2,p. 237-240,2019年01月,研究論文(学術雑誌)
  • Investigation of novel drug for nuclear medicine targeting to cancer specific amino acid transporter, LAT1,Kazuko Kaneda,ZiJian Zhang,Yoshiyuki Manabe,Atsushi Shimoyama,Kazuya Kabayama,Yoshikatsu Kanai,Koichi Fukase,Atsushi Shinohara,CANCER SCIENCE,WILEY,Vol. 109,p. 606-606,2018年12月
  • Porous nanosheet wrapping for live imaging of suspension cells,Hong Zhang,Takuto Aoki,Kanae Hatano,Kazuya Kabayama,Masaru Nakagawa,Koichi Fukase,Yosuke Okamura,JOURNAL OF MATERIALS CHEMISTRY B,ROYAL SOC CHEMISTRY,Vol. 6,No. 41,p. 6622-6628,2018年11月,研究論文(学術雑誌)
  • The NLRP6 Inflammasome Recognizes Lipoteichoic Acid and Regulates Gram-Positive Pathogen Infection,Hideki Hara,Sergey S. Seregin,Dahai Yang,Koichi Fukase,Mathias Chamaillard,Emad S. Alnemri,Naohiro Inohara,Grace Y. Chen,Gabriel Nunez,CELL,CELL PRESS,Vol. 175,No. 6,p. 1651-+,2018年11月,研究論文(学術雑誌)
  • NPC1L1-dependent intestinal cholesterol absorption requires ganglioside GM3 in membrane microdomains,Wataru Nihei,Masakazu Nagafuku,Hirotaka Hayamizu,Yuta Odagiri,Yumi Tamura,Yui Kikuchi,Lucas Veillon,Hirotaka Kanoh,Kei-ichiro Inamori,Kenta Arai,Kazuya Kabayama,Koichi Fukase,Jin-ichi Inokuchi,JOURNAL OF LIPID RESEARCH,AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC,Vol. 59,No. 11,p. 2181-2187,2018年11月,研究論文(学術雑誌)
  • Synthesis of Cyclopropane Fatty Acids by C(sp(3))-C(sp(3)) Cross-Coupling Reaction and Formal Synthesis of -Mycolic Acid,Takanori Iwasaki,Shohei Terahigashi,Yufei Wang,Arisa Tanaka,Hanqing Zhao,Yukari Fujimoto,Koichi Fukase,Nobuaki Kambe,ADVANCED SYNTHESIS & CATALYSIS,WILEY-V C H VERLAG GMBH,Vol. 360,No. 19,p. 3810-3817,2018年10月,研究論文(学術雑誌)
  • Expanding the Applicability of the Metal Labeling of Biomolecules by the RIKEN Click Reaction: A Case Study with Gallium-68 Positron Emission Tomography,Yuka Nakamoto,Ambara R. Pradipta,Hidefumi Mukai,Maki Zouda,Yasuyoshi Watanabe,Almira Kurbangalieva,Peni Ahmadi,Yoshiyuki Manabe,Koichi Fukase,Katsunori Tanaka,CHEMBIOCHEM,WILEY-V C H VERLAG GMBH,Vol. 19,No. 19,p. 2055-2060,2018年10月,研究論文(学術雑誌)
  • Highly Efficient Coupling of Unstable Bicyclic Pyrimidines and Pyrazoles under Basic Conditions, and its Application to the Synthesis of Pharmaceutical Compounds,Takashi Goi,Koichi Fukase,SYNLETT,GEORG THIEME VERLAG KG,Vol. 29,No. 14,p. 1867-1870,2018年09月,研究論文(学術雑誌)
  • Bradyrhizobium Lipid A: Immunological Properties and Molecular Basis of Its Binding to the Myeloid Differentiation Protein-2/Toll-Like Receptor 4 Complex,Luigi Lembo-Fazio,Jean-Marc Billod,Flaviana Di Lorenzo,Ida Paciello,Mateusz Pallach,Sara Vaz-Francisco,Aurora Holgado,Rudi Beyaert,Manuel Fresno,Atsushi Shimoyama,Rosa Lanzetta,Koichi Fukase,Djamel Gully,Eric Giraud,Sonsoles Martin-Santamaria,Maria-Lina Bernardini,Alba Silipo,FRONTIERS IN IMMUNOLOGY,FRONTIERS MEDIA SA,Vol. 9,2018年08月,研究論文(学術雑誌)
  • Bradyrhizobium lipopolysaccharide lipid A: antagonistic properties and molecular basis of its binding to the MD-2/TLR4 complex,L. Lembo-Fazio,J.-M. Billod,F. Di Lorenzo,I. Paciello,M. Pallach,S. Vaz Francisco,A. Holgado,R. Beyaert,M. Fresno,A. Shimoyama,K. Fukase,E. Giraud,S. Martín,Santamaría,M.-L. Bernardini,A. Silipo,Frontiers in Immunology,2018年08月,研究論文(学術雑誌)
  • The second and third amino acids of Pam2 lipopeptides are key for the proliferation of cytotoxic T cells,Yohei Takeda,Masahiro Azuma,Ryoko Hatsugai,Yukari Fujimoto,Masahito Hashimoto,Koichi Fukase,Misako Matsumoto,Tsukasa Seya,INNATE IMMUNITY,SAGE PUBLICATIONS LTD,Vol. 24,No. 5,p. 323-331,2018年07月,研究論文(学術雑誌)
  • Introduction of 4-Chlorophenyl: A Protecting Group for the Hydroxy Function,Yuji Otsuka,Toshihiro Yamamoto,Koichi Fukase,SYNLETT,GEORG THIEME VERLAG KG,Vol. 29,No. 11,p. 1510-1516,2018年07月,研究論文(学術雑誌)
  • Syntheses and Immunological Evaluation of Self-Adjuvanting Clustered N-Acetyl and N-Propionyl Sialyl-Tn Combined with a T-helper Cell Epitope as Antitumor Vaccine Candidates,Tsung-Che Chang,Yoshiyuki Manabe,Yukari Fujimoto,Shino Ohshima,Yoshie Kametani,Kazuya Kabayama,Yuka Nimura,Chun-Cheng Lin,Koichi Fukase,ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,WILEY-V C H VERLAG GMBH,Vol. 57,No. 27,p. 8219-8224,2018年07月,研究論文(学術雑誌)
  • Convergent Synthesis of a Bisecting N-Acetylglucosamine (GlcNAc)-Containing N-Glycan,Yoshiyuki Manabe,Hiroki Shomura,Naoya Minamoto,Masahiro Nagasaki,Yohei Takakura,Katsunori Tanaka,Alba Silipo,Antonio Molinaro,Koichi Fukase,CHEMISTRY-AN ASIAN JOURNAL,WILEY-V C H VERLAG GMBH,Vol. 13,No. 12,p. 1544-1551,2018年06月,研究論文(学術雑誌)
  • Narrower HOMO-LUMO gap attained by conformational switching through peripheral polyarylation in 1,4,5,8-tetraaza-9,10-anthraquinodimethanes,Takanori Suzuki,Yusuke Ishigaki,Kazuma Sugawara,Yu Umezawa,Ryo Katoono,Atsushi Shimoyama,Yoshiyuki Manabe,Koichi Fukase,Takanori Fukushima,TETRAHEDRON,PERGAMON-ELSEVIER SCIENCE LTD,Vol. 74,No. 18,p. 2239-2244,2018年05月,研究論文(学術雑誌)
  • Time-lapse monitoring of TLR2 ligand internalization with newly developed fluorescent probes,Yohei Arai,Kouhei Yokoyama,Yuki Kawahara,Qi Feng,Ippei Ohta,Atsushi Shimoyama,Shinsuke Inuki,Koichi Fukase,Kazuya Kabayama,Yukari Fujimoto,ORGANIC & BIOMOLECULAR CHEMISTRY,ROYAL SOC CHEMISTRY,Vol. 16,No. 20,p. 3824-3830,2018年05月,研究論文(学術雑誌)
  • Lymphoid tissue-resident Alcaligenes LPS induces IgA production without excessive inflammatory responses via weak TLR4 agonist activity,Naoko Shibata,Jun Kunisawa,Koji Hosomi,Yukari Fujimoto,Keisuke Mizote,Naohiro Kitayama,Atsushi Shimoyama,Hitomi Mimuro,Shintaro Sato,Natsuko Kishishita,Ken J. Ishii,Koichi Fukase,Hiroshi Kiyono,MUCOSAL IMMUNOLOGY,NATURE PUBLISHING GROUP,Vol. 11,No. 3,p. 693-702,2018年05月,研究論文(学術雑誌)
  • Branched Sialylated N-glycans Are Accumulated in Brain Synaptosomes and Interact with Siglec-H,Mai Handa-Narumi,Takeshi Yoshimura,Hiroyuki Konishi,Yuko Fukata,Yoshiyuki Manabe,Katsunori Tanaka,Guang-ming Bao,Hiroshi Kiyam,Koichi Fukase,Kazuhiro Ienaka,CELL STRUCTURE AND FUNCTION,JAPAN SOC CELL BIOLOGY,Vol. 43,No. 2,p. 141-152,2018年,研究論文(学術雑誌)
  • BODIPY標識ラクトシルセラミドを用いた糖脂質の動態解析,新井 健太,蟹江 善美,蟹江 治,樺山 一哉,深瀬 浩一,生命科学系学会合同年次大会,生命科学系学会合同年次大会運営事務局,Vol. 2017年度,p. [3P-0021],2017年12月
  • Synthesis and Functional Studies of Self-Adjuvanting Cancer Vaccine Containing B Cell Epitope Derived from HER2.,Feng, Q,Kabayama, K,Manabe, Y,Miyamoto, A,Kametani, Y,Fukase, K,Peptide Science,p. 56-57,2017年12月,研究論文(学術雑誌)
  • A Comprehensive Study of the Interaction between Peptidoglycan Fragments and the Extracellular Domain of Mycobacterium tuberculosis Ser/Thr Kinase PknB,Qianqian Wang,Roberta Marchetti,Sladjana Prisic,Kentaro Ishii,Yohei Arai,Ippei Ohta,Shinsuke Inuki,Susumu Uchiyama,Alba Silipo,Antonio Molinaro,Robert N. Husson,Koichi Fukase,Yukari Fujimoto,CHEMBIOCHEM,WILEY-V C H VERLAG GMBH,Vol. 18,No. 21,p. 2094-2098,2017年11月,研究論文(学術雑誌)
  • Calcineurin inhibitors exacerbate coronary arteritis via the MyD88 signalling pathway in a murine model of Kawasaki disease,K. Murata,Y. Motomura,T. Tanaka,S. Kanno,T. Yano,M. Onimaru,A. Shimoyama,H. Nishio,Y. Sakai,M. Oh-Hora,H. Hara,K. Fukase,H. Takada,S. Masuda,S. Ohga,S. Yamasaki,T. Hara,Clinical and Experimental Immunology,WILEY,Vol. 190,No. 1,p. 54-67,2017年10月,研究論文(学術雑誌)
  • Funiculosin variants and phosphorylated derivatives promote innate immune responses via the Toll-like receptor 4/myeloid differentiation factor-2 complex,Naoki Okamoto,Keisuke Mizote,Hiroe Honda,Akinori Saeki,Yasuharu Watanabe,Tomonni Yamaguchi-Miyamoto,Ryutaro Fukui,Natsuko Tanimura,Yuji Motoi,Sachiko Akashi-Takamura,Tatsuhisa Kato,Shigeto Fujishita,Takahito Kimura,Umeharu Ohto,Toshiyuki Shimizu,Takatsugu Hirokawa,Kensuke Miyake,Koichi Fukase,Yukari Fujimoto,Yoshinori Nagai,Kiyoshi Takatsu,JOURNAL OF BIOLOGICAL CHEMISTRY,AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC,Vol. 292,No. 37,p. 15378-15394,2017年09月,研究論文(学術雑誌)
  • Synthetic analogs of an Entamoeba histolytica glycolipid designed to combat intracellular Leishmania infection,Siew Ling Choy,Hannah Bernin,Toshihiko Aiba,Eugenia Bifeld,Sarah Corinna Lender,Melina Muehlenpfordt,Jill Noll,Julia Eick,Claudia Marggraff,Hanno Niss,Nestor Gonzalez Roldan,Shinji Tanaka,Masato Kitamura,Koichi Fukase,Joachim Clos,Egbert Tannich,Yukari Fujimoto,Hannelore Lotter,SCIENTIFIC REPORTS,NATURE PUBLISHING GROUP,Vol. 7,No. 1,p. 9472-9472,2017年08月,研究論文(学術雑誌)
  • Syntheses of N-aryl-protected glucosamines and their stereoselectivity in chemical glycosylations,Yuji Otsuka,Toshihiro Yamamoto,Koichi Fukase,TETRAHEDRON LETTERS,PERGAMON-ELSEVIER SCIENCE LTD,Vol. 58,No. 31,p. 3019-3023,2017年08月,研究論文(学術雑誌)
  • Total Synthesis of Cardiolipins Containing Chiral Cyclopropane Fatty Acids,Shinsuke Inuki,Ippei Ohta,Shunichi Ishibashi,Masayuki Takamatsu,Koichi Fukase,Yukari Fujimoto,JOURNAL OF ORGANIC CHEMISTRY,AMER CHEMICAL SOC,Vol. 82,No. 15,p. 7832-7838,2017年08月,研究論文(学術雑誌)
  • 合成糖脂質分子を用いた細胞膜動態の時空間解析,新井 健太,樺山 一哉,蟹江 治,深瀬 浩一,脂質生化学研究,日本脂質生化学会,Vol. 59,p. 158-159,2017年06月
  • Bio-inspired Domino Reduction of Nitroarenes by Acrolein-Amine Conjugates in One-pot Operation,Masayuki Takamatsu,Koichi Fukase,Katsunori Tanaka,CHEMISTRY LETTERS,CHEMICAL SOC JAPAN,Vol. 46,No. 6,p. 811-813,2017年06月,研究論文(学術雑誌)
  • Employing BINOL-Phosphoroselenoyl Chloride for Selective Inositol Phosphorylation and Synthesis of Glycosyl Inositol Phospholipid from Entamoeba histolytica,Toshihiko Aiba,Sae Suehara,Siew-Ling Choy,Yuuki Maekawa,Hannelore Lotter,Toshiaki Murai,Shinsuke Inuki,Koichi Fukase,Yukari Fujimoto,CHEMISTRY-A EUROPEAN JOURNAL,WILEY-V C H VERLAG GMBH,Vol. 23,No. 34,p. 8304-8308,2017年06月,研究論文(学術雑誌)
  • Development of α1,6-fucosyltransferase inhibitors through the diversity-oriented syntheses of GDP-fucose mimics using the coupling between alkyne and sulfonyl azide.,Manabe Y,Kasahara S,Takakura Y,Yang X,Takamatsu S,Kamada Y,Miyoshi E,Yoshidome D,Fukase K,Bioorganic & medicinal chemistry,Vol. 25,No. 11,p. 2844-2850,2017年06月,研究論文(学術雑誌)
  • GM3合成酵素ノックアウトマウスは腸管からのコレステロール吸収抑制を介して高コレステロール血症に抵抗性を示す,二瓶 渉,永福 正和,田村 友美,稲森 啓一郎,新井 健太,樺山 一哉,深瀬 浩一,井ノ口 仁一,日本薬学会年会要旨集,(公社)日本薬学会,Vol. 137年会,No. 3,p. 53-53,2017年03月
  • Flow Dehydration and Hydrogenation of Allylic Alcohols: Application to the Waste-Free Synthesis of Pristane,Akihiro Furuta,Yuki Hirobe,Takahide Fukuyama,Ilhyong Ryu,Yoshiyuki Manabe,Koichi Fukase,EUROPEAN JOURNAL OF ORGANIC CHEMISTRY,WILEY-V C H VERLAG GMBH,Vol. 2017,No. 10,p. 1365-1368,2017年03月,研究論文(学術雑誌)
  • Product Selectivity of Esterification of L-Aspartic Acid and L-Glutamic Acid Using Chlorotrimethylsilane,Tomohiro Takaishi,Minoru Izumi,Ryo Ota,Chieri Inoue,Hiromasa Kiyota,Koichi Fukase,NATURAL PRODUCT COMMUNICATIONS,NATURAL PRODUCTS INC,Vol. 12,No. 2,p. 247-249,2017年02月,研究論文(学術雑誌)
  • Synthesis of Peptidoglycan Fragments from Enterococcus faecalis with Fmoc-Strategy for Glycan Elongation,Ning Wang,Hiroki Hasegawa,Cheng-yuan Huang,Koichi Fukase,Yukari Fujimoto,CHEMISTRY-AN ASIAN JOURNAL,WILEY-V C H VERLAG GMBH,Vol. 12,No. 1,p. 27-30,2017年01月,研究論文(学術雑誌)
  • Discovery of a Novel Scaffold as an Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitor Based on the Pyrrolopiperazinone Alkaloid, Longamide B,Zenyu Shiokawa,Emi Kashiwabara,Daisuke Yoshidome,Koichi Fukase,Shinsuke Inuki,Yukari Fujimoto,ChemMedChem,Wiley,Vol. 11,No. 24,p. 2682-2689,2016年12月,研究論文(学術雑誌)
  • Chemical Synthesis of a Complex-Type N-Glycan Containing a Core Fucose,Masahiro Nagasaki,Yoshiyuki Manabe,Naoya Minamoto,Katsunori Tanaka,Alba Silipo,Antonio Molinaro,Koichi Fukase,JOURNAL OF ORGANIC CHEMISTRY,AMER CHEMICAL SOC,Vol. 81,No. 22,p. 10600-10616,2016年11月,研究論文(学術雑誌)
  • Isolated Polar Amino Acid Residues Modulate Lipid Binding in the Large Hydrophobic Cavity of CD1d,Shinsuke Inuki,Toshihiko Aiba,Natsumi Hirata,Osamu Ichihara,Daisuke Yoshidome,Shunsuke Kita,Katsumi Maenaka,Koichi Fukase,Yukari Fujimoto,ACS CHEMICAL BIOLOGY,AMER CHEMICAL SOC,Vol. 11,No. 11,p. 3132-3139,2016年11月,研究論文(学術雑誌)
  • One-Pot Evolution of AgeladineA through a Bio-Inspired Cascade towards Selective Modulators of Neuronal Differentiation,Takayuki Iwata,Satoshi Otsuka,Kazuki Tsubokura,Almira Kurbangalieva,Daisuke Arai,Koichi Fukase,Yoichi Nakao,Katsunori Tanaka,CHEMISTRY-A EUROPEAN JOURNAL,WILEY-V C H VERLAG GMBH,Vol. 22,No. 41,p. 14707-14716,2016年10月,研究論文(学術雑誌)
  • A Reduction-Based Sensor for Acrolein Conjugates with the Inexpensive Nitrobenzene as an Alternative to Monoclonal Antibody,Masayuki Takamatsu,Koichi Fukase,Ritsuko Oka,Shinobu Kitazume,Naoyuki Taniguchi,Katsunori Tanaka,SCIENTIFIC REPORTS,NATURE PUBLISHING GROUP,Vol. 6,p. 35872-35872,2016年10月,研究論文(学術雑誌)
  • Characterization of a Novel D-Glycero-D-talo-oct-2-ulosonic acid-substituted Lipid A Moiety in the Lipopolysaccharide Produced by the Acetic Acid Bacterium Acetobacter pasteurianus NBRC 3283,Masahito Hashimoto,Mami Ozono,Maiko Furuyashiki,Risako Baba,Shuhei Hashiguchi,Yasuo Suda,Koichi Fukase,Yukari Fujimoto,JOURNAL OF BIOLOGICAL CHEMISTRY,AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC,Vol. 291,No. 40,p. 21184-21194,2016年09月,研究論文(学術雑誌)
  • Peptidoglycan Microarray as a Novel Tool to Explore Protein-Ligand Recognition,Ning Wang,Akiyoshi Hirata,Kiyoshi Nokihara,Koichi Fukase,Yukari Fujimoto,BIOPOLYMERS,WILEY-BLACKWELL,Vol. 106,No. 4,p. 422-429,2016年07月,研究論文(学術雑誌)
  • Efficient Synthesis of the Disialylated Tetrasaccharide Motif in N-Glycans through an Amide-Protection Strategy,Jiazhou Zhou,Yoshiyuki Manabe,Katsunori Tanaka,Koichi Fukase,CHEMISTRY-AN ASIAN JOURNAL,WILEY-V C H VERLAG GMBH,Vol. 11,No. 9,p. 1436-1440,2016年05月,研究論文(学術雑誌)
  • Efficient Synthesis of (–)-Hanishin, (–)-Longamide B, and (–)-Longamide B Methyl Ester through Piperazinone Formation from 1,2-Cyclic Sulfamidates,Koichi Fukase,Yukari Fujimoto,Zenyu Shiokawa,Shinsuke Inuki,Synlett,Georg Thieme Verlag {KG},Vol. 27,No. 4,p. 616-620,2016年03月,研究論文(学術雑誌)
  • Development of a simple assay system for protein-stabilizing efficiency based on hemoglobin protection against denaturation and measurement of the cooperative effect of mixing protein stabilizers,Siyu Chen,Yoshiyuki Manabe,Naoya Minamoto,Naoka Saiki,Koichi Fukase,BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY,TAYLOR & FRANCIS LTD,Vol. 80,No. 10,p. 1874-1878,2016年,研究論文(学術雑誌)
  • Regioselective phosphorylation of myo-inositol with BINOL-derived phosphoramidites and its application for protozoan lysophosphatidylinositol,Toshihiko Aiba,Masaki Sato,Daichi Umegaki,Takanori Iwasaki,Nobuaki Kambe,Koichi Fukase,Yukari Fujimoto,ORGANIC & BIOMOLECULAR CHEMISTRY,ROYAL SOC CHEMISTRY,Vol. 14,No. 28,p. 6672-6675,2016年,研究論文(学術雑誌)
  • Synthesis of characteristic Mycobacterium peptidoglycan (PGN) fragments utilizing with chemoenzymatic preparation of meso-diaminopimelic acid (DAP), and their modulation of innate immune responses,Qianqian Wang,Yusuke Matsuo,Ambara R. Pradipta,Naohiro Inohara,Yukari Fujimoto,Koichi Fukase,ORGANIC & BIOMOLECULAR CHEMISTRY,ROYAL SOC CHEMISTRY,Vol. 14,No. 3,p. 1013-1023,2016年,研究論文(学術雑誌)
  • Synthesis of the Conjugates of Tumor Antigens with Adjuvants for the Efficient Cancer Immunotherapy.,Manabe, Y,Chang, T-C,Li, H-S,Terao, N,Takamatsu, S,Tanemura, M,Miyoshi, E,Fukase, K,Peptide Science,p. 77-78,2015年11月,研究論文(学術雑誌)
  • 分子イメージングによる糖鎖複合体の動態解析,深瀬浩一,田中克典,下山敦史,日本分子イメージング学会機関誌,Vol. 8(2),p. 18-25,2015年05月
  • Effective Synthesis of Oligosaccharide under Microfiuidic Conditions,Koichi Fukase,Atsushi Shimoyama,Yoshiyuki Manabe,JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN,SOC SYNTHETIC ORGANIC CHEM JPN,Vol. 73,No. 5,p. 452-459,2015年05月,研究論文(学術雑誌)
  • 効率的α-シアリル化反応の開発と生物活性分子の創製,真鍋良幸,深瀬浩一,化学(5月号),Vol. 70,p. 66-67,2015年04月
  • S,Koichi Fukase,Katsunori Tanaka,Yukari Fujimoto,Atsushi Shimoyama,Yoshiyuki Manabe,Glycochemical Synthesis: Strategies and Applications,Wiley Blackwell,p. 205-219,2015年01月01日,論文集(書籍)内論文
  • Microbial glycoconjugates recognition with tlrs and nlrs in innate immunity,Yukari Fujimoto,Koichi Fukase,Glycoscience: Biology and Medicine,Springer Japan,p. 685-690,2015年01月01日,論文集(書籍)内論文
  • Chemical Approach to a Whole Body Imaging of Sialo-N-Linked Glycans,Katsunori Tanaka,Koichi Fukase,SIALOGLYCO CHEMISTRY AND BIOLOGY II: TOOLS AND TECHNIQUES TO IDENTIFY AND CAPTURE SIALOGLYCANS,SPRINGER INTERNATIONAL PUBLISHING AG,Vol. 367,p. 201-230,2015年,論文集(書籍)内論文
  • Synthesis and Biofunctional Study of Immunomodulative Lipopolysaccharide Partial Structures.,Shimoyama, A,Mizote. K,Fujimoto, Y,Fukase, K,Glycoconjugate J.,Vol. 32,2015年,研究論文(国際会議プロシーディングス)
  • Imino [4+4] cycloaddition products as exclusive and biologically relevant acrolein-amine conjugates are intermediates of 3-formyl-3,4-dehydropiperidine(FDP), an acrolein biomarker,Masayuki Takamatsu,Koichi Fukase,Almira Kurbangalieva,Katsunori Tanaka,BIOORGANIC & MEDICINAL CHEMISTRY,PERGAMON-ELSEVIER SCIENCE LTD,Vol. 22,No. 22,p. 6380-6386,2014年11月,研究論文(学術雑誌)
  • Revisiting the Bromination of C-H Bonds with Molecular Bromine by Using a Photo-Microflow System,Yoshiyuki Manabe,Yuriko Kitawaki,Masahiro Nagasaki,Koichi Fukase,Hiroshi Matsubara,Yoshiko Hino,Takahide Fukuyama,Ilhyong Ryu,CHEMISTRY-A EUROPEAN JOURNAL,WILEY-V C H VERLAG GMBH,Vol. 20,No. 40,p. 12750-12753,2014年09月,研究論文(学術雑誌)
  • Solid-phase Synthesis of Bacterial Cell Wall Peptidoglycan Fragments,Yuichiro Kadonaga,Ning Wang,Yukari Fujimoto,Koichi Fukase,CHEMISTRY LETTERS,CHEMICAL SOC JAPAN,Vol. 43,No. 9,p. 1461-1463,2014年09月,研究論文(学術雑誌)
  • Efficient Glycosylation Using In(OTf)(3) as a Lewis Acid: Activation of N-Phenyltrifluoroacetimidate or Thioglycosides with Halogenated Reagents or PhIO,Regina M. Salmasan,Yoshiyuki Manabe,Yuriko Kitawaki,Tsung-Che Chang,Koichi Fukase,CHEMISTRY LETTERS,CHEMICAL SOC JAPAN,Vol. 43,No. 6,p. 956-958,2014年06月,研究論文(学術雑誌)
  • Molecular basis for bacterial peptidoglycan recognition by LysM domains,Stephane Mesnage,Mariano Dellarole,Nicola J. Baxter,Jean-Baptiste Rouget,Jordan D. Dimitrov,Ning Wang,Yukari Fujimoto,Andrea M. Hounslow,Sebastien Lacroix-Desmazes,Koichi Fukase,Simon J. Foster,Michael P. Williamson,NATURE COMMUNICATIONS,NATURE PUBLISHING GROUP,Vol. 5,p. 4269-4269,2014年06月,研究論文(学術雑誌)
  • Direct Guanylation of Amino Groups by Cyanamide in Water: Catalytic Generation and Activation of Unsubstituted Carbodiimide by Scandium(III) Triflate,Kazuki Tsubokura,Takayuki Iwata,Misako Taichi,Almira Kurbangalieva,Koichi Fukase,Yoichi Nakao,Katsunori Tanaka,SYNLETT,GEORG THIEME VERLAG KG,Vol. 25,No. 9,p. 1302-1306,2014年06月,研究論文(学術雑誌)
  • The attenuated inflammation of MPL is due to the lack of CD14-dependent tight dimerization of the TLR4/MD2 complex at the plasma membrane,Natsuko Tanimura,Shin-ichiroh Saitoh,Umeharu Ohto,Sachiko Akashi-Takamura,Yukari Fujimoto,Koichi Fukase,Toshiyuki Shimizu,Kensuke Miyake,INTERNATIONAL IMMUNOLOGY,OXFORD UNIV PRESS,Vol. 26,No. 6,p. 307-314,2014年06月,研究論文(学術雑誌)
  • Facile Preparation of 1,5-Diazacyclooctanes from Unsaturated Imines: Effects of the Hydroxyl Groups on [4+4] Dimerization,Katsunori Tanaka,Risa Matsumoto,Ambara R. Pradipta,Yasutaka Kitagawa,Mitsutaka Okumura,Yoshiyuki Manabe,Koichi Fukase,SYNLETT,GEORG THIEME VERLAG KG,Vol. 25,No. 7,p. 1026-1030,2014年04月,研究論文(学術雑誌)
  • One-Pot Synthesis of N-Acetyl- and N-Glycolylneuraminic Acid Capped Trisaccharides and Evaluation of Their Influenza A(H1N1) Inhibition,Yun Hsu,Hsiu-Hwa Ma,Larry S. Lico,Jia-Tsrong Jan,Koichi Fukase,Yosuke Uchinashi,Medel Manuel L. Zulueta,Shang-Cheng Hung,ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,WILEY-V C H VERLAG GMBH,Vol. 53,No. 9,p. 2413-2416,2014年02月,研究論文(学術雑誌)
  • Practical and Efficient Method for α-Sialylation with an Azide Sialyl Donor Using a Microreactor.,Uchinashi, Y,Tanaka, K,Manabe, Y,Fujimoto, Y,Fukase, K,Vol. 33,No. 2,p. 55-67,2014年02月,研究論文(学術雑誌)
  • A cascading reaction sequence involving ligand-directed azaelectrocyclization and autooxidation-induced fluorescence recovery enables visualization of target proteins on the surfaces of live cells,Katsunori Tanaka,Masataka Kitadani,Ayumi Tsutsui,Ambara R. Pradipta,Rie Imamaki,Shinobu Kitazume,Naoyuki Taniguchi,Koichi Fukase,ORGANIC & BIOMOLECULAR CHEMISTRY,ROYAL SOC CHEMISTRY,Vol. 12,No. 9,p. 1412-1418,2014年,研究論文(学術雑誌)
  • Human serum amyloid P component is a novel peptidoglycan recognition protein inducing complement-independent phagocytosis of Staphylococcus aureus,J. -H. An,K. Kurokawa,D. -J. Jung,Y. Fujimoto,K. Fukase,B. L. Lee,MOLECULAR IMMUNOLOGY,PERGAMON-ELSEVIER SCIENCE LTD,Vol. 56,No. 3,p. 301-301,2013年12月
  • Separation and characterization of the immunostimulatory components in unpolished rice black vinegar (kurozu),Masahito Hashimoto,Kyoko Obara,Mami Ozono,Maiko Furuyashiki,Tsuyoshi Ikeda,Yasuo Suda,Koichi Fukase,Yukari Fujimoto,Hiroshi Shigehisa,JOURNAL OF BIOSCIENCE AND BIOENGINEERING,SOC BIOSCIENCE BIOENGINEERING JAPAN,Vol. 116,No. 6,p. 688-696,2013年12月,研究論文(学術雑誌)
  • Development of bis-unsaturated ester aldehydes as amino-glue probes: sequential double azaelectrocyclization as a promising strategy for bioconjugation,Katsunori Tanaka,Yuka Nakamoto,Eric R. O. Siwu,Ambara R. Pradipta,Koji Morimoto,Takeshi Fujiwara,Suguru Yoshida,Takamitsu Hosoya,Yuki Tamura,Go Hirai,Mikiko Sodeoka,Koichi Fukase,ORGANIC & BIOMOLECULAR CHEMISTRY,ROYAL SOC CHEMISTRY,Vol. 11,No. 42,p. 7326-7333,2013年11月,研究論文(学術雑誌)
  • Human SAP Is a Novel Peptidoglycan Recognition Protein That Induces Complement-Independent Phagocytosis of Staphylococcus aureus,Jang-Hyun An,Kenji Kurokawa,Dong-Jun Jung,Min-Jung Kim,Chan-Hee Kim,Yukari Fujimoto,Koichi Fukase,K. Mark Coggeshall,Bok Luel Lee,JOURNAL OF IMMUNOLOGY,AMER ASSOC IMMUNOLOGISTS,Vol. 191,No. 6,p. 3319-3327,2013年09月,研究論文(学術雑誌)
  • Cytotoxic Activity of Ursolic Acid Derivatives Obtained by Isolation and Oxidative Derivatization,Kishor Mazumder,Katsunori Tanaka,Koichi Fukase,MOLECULES,MDPI AG,Vol. 18,No. 8,p. 8929-8944,2013年08月
  • Synthesis and biological activity of phosphoglycolipids from Thermus thermophilus,Yukari Fujimoto,Kunihiro Mitsunobe,Satoko Fujiwara,Motoko Mori,Masahiro Hashimoto,Yasuo Suda,Shoichi Kusumoto,Koichi Fukase,ORGANIC & BIOMOLECULAR CHEMISTRY,ROYAL SOC CHEMISTRY,Vol. 11,No. 30,p. 5034-5041,2013年08月,研究論文(学術雑誌)
  • Whole-body imaging of tumor cells by azaelectrocyclization: Visualization of metastasis dependence on glycan structure,Katsunori Tanaka,Kenta Moriwaki,Satomi Yokoi,Koichi Koyama,Eiji Miyoshi,Koichi Fukase,BIOORGANIC & MEDICINAL CHEMISTRY,PERGAMON-ELSEVIER SCIENCE LTD,Vol. 21,No. 5,p. 1074-1077,2013年03月,研究論文(学術雑誌)
  • Glycan Sequence-Dependent Nod2 Activation Investigated by Using a Chemically Synthesized Bacterial Peptidoglycan Fragment Library,Ning Wang,Cheng-yuan Huang,Mizuho Hasegawa,Naohiro Inohara,Yukari Fujimoto,Koichi Fukase,CHEMBIOCHEM,WILEY-V C H VERLAG GMBH,Vol. 14,No. 4,p. 482-488,2013年03月,研究論文(学術雑誌)
  • Nickel-Butadiene Catalytic System for the Cross-Coupling of Bromoalkanoic Acids with Alkyl Grignard Reagents: A Practical and Versatile Method for Preparing Fatty Acids,Takanori Iwasaki,Kiyokazu Higashikawa,Vutukuri P. Reddy,Willbe W. S. Ho,Yukari Fujimoto,Koichi Fukase,Jun Terao,Hitoshi Kuniyasu,Nobuaki Kambe,CHEMISTRY-A EUROPEAN JOURNAL,WILEY-V C H VERLAG GMBH,Vol. 19,No. 9,p. 2956-2960,2013年02月,研究論文(学術雑誌)
  • A conformationally fixed analog of the peptide mimic Grb2-SH2 domain: synthesis and evaluation against the A431 cancer cell,Takayuki Iwata,Katsunori Tanaka,Tsuyoshi Tahara,Satoshi Nozaki,Hirotaka Onoe,Yasuyoshi Watanabe,Koichi Fukase,MOLECULAR BIOSYSTEMS,ROYAL SOC CHEMISTRY,Vol. 9,No. 5,p. 1019-1025,2013年,研究論文(学術雑誌)
  • Nod1/Nod2 リガンドとしての細菌細胞壁ペプチドグリカン;化学合成と免疫調節活性,藤本ゆかり,A. R. Pradipta,N. Wang,長谷川瑞穂,猪原直弘,深瀬浩一,エンドトキシン・自然免疫研究,Vol. 16,p. 26-36,2013年
  • Innate immunomodulation by lipophilic termini of lipopolysaccharide; synthesis of lipid As from Porphyromonas gingivalis and other bacteria and their immunomodulative responses,Yukari Fujimoto,Atsushi Shimoyama,Akinori Saeki,Naohiro Kitayama,Chika Kasamatsu,Hiroko Tsutsui,Koichi Fukase,MOLECULAR BIOSYSTEMS,ROYAL SOC CHEMISTRY,Vol. 9,No. 5,p. 987-996,2013年,研究論文(学術雑誌)
  • Bio-imaging and cancer targeting with glycoproteins and N-glycans,Koichi Fukase,Katsunori Tanaka,CURRENT OPINION IN CHEMICAL BIOLOGY,ELSEVIER SCI LTD,Vol. 16,No. 5-6,p. 614-621,2012年12月
  • Efficient synthesis of 2,6,9-triazabicyclo[3.3.1]nonanes through amine-mediated formal [4+4] reaction of unsaturated imines,Katsunori Tanaka,Eric R. O. Siwu,Shinji Hirosaki,Takayuki Iwata,Risa Matsumoto,Yasutaka Kitagawa,Ambara R. Pradipta,Mitsutaka Okumura,Koichi Fukase,TETRAHEDRON LETTERS,PERGAMON-ELSEVIER SCIENCE LTD,Vol. 53,No. 44,p. 5899-5902,2012年10月,研究論文(学術雑誌)
  • Synthesis and immunomodulatory activities of Helicobacter pylori lipophilic terminus of lipopolysaccharide including lipid A,Yukari Fujimoto,Atsushi Shimoyama,Yasuo Suda,Koichi Fukase,CARBOHYDRATE RESEARCH,ELSEVIER SCI LTD,Vol. 356,p. 37-43,2012年07月,研究論文(学術雑誌)
  • Structural Characterization of Neutral and Acidic Glycolipids from Thermus thermophilus HB8,Yasuo Suda,Fumiaki Okazaki,Yushi Hasegawa,Seiji Adachi,Koichi Fukase,Susumu Kokubo,Seiki Kuramitsu,Shoichi Kusumoto,PLOS ONE,PUBLIC LIBRARY SCIENCE,Vol. 7,No. 7,2012年07月,研究論文(学術雑誌)
  • Structural basis of species-specific endotoxin sensing by innate immune receptor TLR4/MD-2,Umeharu Ohto,Koichi Fukase,Kensuke Miyake,Toshiyuki Shimizu,PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,NATL ACAD SCIENCES,Vol. 109,No. 19,p. 7421-7426,2012年05月,研究論文(学術雑誌)
  • Structural and mechanistic analysis of the membrane-embedded glycosyltransferase WaaA required for lipopolysaccharide synthesis,Helgo Schmidt,Guido Hansen,Sonia Singh,Anna Hanuszkiewicz,Buko Lindner,Koichi Fukase,Ronald W. Woodard,Otto Holst,Rolf Hilgenfeld,Uwe Mamat,Jeroen R. Mesters,PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,NATL ACAD SCIENCES,Vol. 109,No. 16,p. 6253-6258,2012年04月,研究論文(学術雑誌)
  • Auxiliary-directed oxidation of ursolic acid by 'Ru'-porphyrins: chemical modulation of cytotoxicity against tumor cell lines,Katsunori Tanaka,Kishor Mazumder,Eric R. O. Siwu,Satoshi Nozaki,Yasuyoshi Watanabe,Koichi Fukase,TETRAHEDRON LETTERS,PERGAMON-ELSEVIER SCIENCE LTD,Vol. 53,No. 14,p. 1756-1759,2012年04月,研究論文(学術雑誌)
  • Template-Assisted and Self-Activating Clicked Peptide as a Synthetic Mimic of the SH2 Domain,Katsunori Tanaka,Sanae Shirotsuki,Takayuki Iwata,Chika Kageyama,Tsuyoshi Tahara,Satoshi Nozaki,Eric R. O. Siwu,Satoru Tamura,Shunsuke Douke,Nobutoshi Murakam,Hirotaka Onoe,Yasuyoshi Watanabe,Koichi Fukase,ACS CHEMICAL BIOLOGY,AMER CHEMICAL SOC,Vol. 7,No. 4,p. 637-645,2012年04月,研究論文(学術雑誌)
  • Development of Azaelectrocyclization-Based Labeling and Application to Noninvasive Imaging and Targeting Using N-Glycan Derivatives-In Pursuit of N-Glycan Functions on Proteins, Dendrimers, and Living Cells-,Katsunori Tanaka,Koichi Fukase,TRENDS IN GLYCOSCIENCE AND GLYCOTECHNOLOGY,GAKUSHIN PUBL CO,Vol. 24,No. 136,p. 47-64,2012年03月
  • Cell surface biotinylation by azaelectrocyclization: Easy-handling and versatile approach for living cell labeling,Katsunori Tanaka,Satomi Yokoi,Koji Morimoto,Takayuki Iwata,Yuka Nakamoto,Kaori Nakayama,Koichi Koyama,Takeshi Fujiwara,Koichi Fukase,BIOORGANIC & MEDICINAL CHEMISTRY,PERGAMON-ELSEVIER SCIENCE LTD,Vol. 20,No. 6,p. 1865-1868,2012年03月,研究論文(学術雑誌)
  • Synthesis of Bacterial Glycoconjugates and Their Bio-functional Studies in Innate Immunity,Koichi Fukase,Yukari Fujimoto,Atsushi Shimoyama,Katsunori Tanaka,JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN,SOC SYNTHETIC ORGANIC CHEM JPN,Vol. 70,No. 2,p. 113-130,2012年02月
  • Discovery and application of 6 pi-azaelectrocyclization to natural product synthesis and synthetic biology,Katsunori Tanaka,Shigeo Katsumura,Koichi Fukase,SCIENCE CHINA-CHEMISTRY,SCIENCE PRESS,Vol. 55,No. 1,p. 19-30,2012年01月
  • Peptidoglycan as Innate Immunomodulator; Chemical Synthesis of Its Fragments, Immunostimulatory Activities, and Natural Nod1 Ligand Structures in the Environments / Fermented food,Y. Fujimoto,A. R. Pradipta,M. Hashimoto,S. Kan,H. Shigehisa,K. Fukase,Peptide Science,p. 97-98,2012年,研究論文(国際会議プロシーディングス)
  • Peptidoglycan as Nod1 ligand; fragment structures in the environment, chemical synthesis, and their innate immunostimulation,Yukari Fujimoto,Ambara Rachmat Pradipta,Naohiro Inohara,Koichi Fukase,NATURAL PRODUCT REPORTS,ROYAL SOC CHEMISTRY,Vol. 29,No. 5,p. 568-579,2012年
  • Oligosaccharide Synthesis on Solid, Soluble Polymer, and Tag Supports,Katsunori Tanaka,Koichi Fukase,Solid-Phase Organic Synthesis: Concepts, Strategies, and Applications,John Wiley and Sons,p. 489-530,2011年12月15日,論文集(書籍)内論文
  • Chemical Synthesis of Helicobacter pylori Lipopolysaccharide Partial Structures and their Selective Proinflammatory Responses,Atsushi Shimoyama,Akinori Saeki,Natsuko Tanimura,Hiroko Tsutsui,Kensuke Miyake,Yasuo Suda,Yukari Fujimoto,Koichi Fukase,CHEMISTRY-A EUROPEAN JOURNAL,WILEY-V C H VERLAG GMBH,Vol. 17,No. 51,p. 14464-14474,2011年12月,研究論文(学術雑誌)
  • Stereoselective Glycosylation of 3-Deoxy-D-manno-2-octulosonic Acid with Batch and Microfluidic Methods,Atsushi Shimoyama,Yukari Fujimoto,Koichi Fukase,SYNLETT,GEORG THIEME VERLAG KG,No. 16,p. 2359-2362,2011年10月,研究論文(学術雑誌)
  • Exploring a Unique Reactivity of 6 pi-Azaelectrocyclization to Enzyme Inhibition, Natural Products Synthesis, and Molecular Imaging: An Approach to Chemical Biology by Synthetic Chemists,Katsunori Tanaka,Koichi Fukase,Shigeo Katsumura,SYNLETT,GEORG THIEME VERLAG KG,No. 15,p. 2115-2139,2011年09月,研究論文(学術雑誌)
  • Ursolic acid derivatives from Bangladeshi medicinal plant, Saurauja roxburghii: Isolation and cytotoxic activity against A431 and C6 glioma cell lines,Kishor Mazumder,Eric R. O. Siwu,Satoshi Nozaki,Yasuyoshi Watanabe,Katsunori Tanaka,Koichi Fukase,PHYTOCHEMISTRY LETTERS,ELSEVIER,Vol. 4,No. 3,p. 287-291,2011年09月,研究論文(学術雑誌)
  • Nod1 Ligands Induce Site-Specific Vascular Inflammation,Hisanori Nishio,Shunsuke Kanno,Sagano Onoyama,Kazuyuki Ikeda,Tamami Tanaka,Koichi Kusuhara,Yukari Fujimoto,Koichi Fukase,Katsuo Sueishi,Toshiro Hara,ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY,LIPPINCOTT WILLIAMS & WILKINS,Vol. 31,No. 5,p. 1093-U383,2011年05月,研究論文(学術雑誌)
  • Failure of mycoplasma lipoprotein MALP-2 to induce NK cell activation through dendritic cell TLR2,Ryoko Sawahata,Hiroaki Shime,Sayuri Yamazaki,Norimitsu Inoue,Takashi Akazawa,Yukari Fujimoto,Koichi Fukase,Misako Matsumoto,Tsukasa Seya,MICROBES AND INFECTION,ELSEVIER,Vol. 13,No. 4,p. 350-358,2011年04月,研究論文(学術雑誌)
  • Structures, Synthesis, and Human Nod1 Stimulation of Immunostimulatory Bacterial Peptidoglycan Fragments in the Environment,Yukari Fujimoto,Koichi Fukase,JOURNAL OF NATURAL PRODUCTS,AMER CHEMICAL SOC,Vol. 74,No. 3,p. 518-525,2011年03月
  • Reinvestigation of the C5-acetamide sialic acid donor for alpha-selective sialylation: practical procedure under microfluidic conditions,Yosuke Uchinashi,Masahiro Nagasaki,Jiazhou Zhou,Katsunori Tanaka,Koichi Fukase,ORGANIC & BIOMOLECULAR CHEMISTRY,ROYAL SOC CHEMISTRY,Vol. 9,No. 20,p. 7243-7248,2011年,研究論文(学術雑誌)
  • Target-selective fluorescent "switch-on" protein labeling by 6 pi-azaelectrocyclization,Katsunori Tanaka,Masataka Kitadani,Koichi Fukase,ORGANIC & BIOMOLECULAR CHEMISTRY,ROYAL SOC CHEMISTRY,Vol. 9,No. 15,p. 5346-5349,2011年,研究論文(学術雑誌)
  • The Peptide Sequence of Diacyl Lipopeptides Determines Dendritic Cell TLR2-Mediated NK Activation,Masahiro Azuma,Ryoko Sawahata,Yuusuke Akao,Takashi Ebihara,Sayuri Yamazaki,Misako Matsumoto,Masahito Hashimoto,Koichi Fukase,Yukari Fujimoto,Tsukasa Seya,PLOS ONE,PUBLIC LIBRARY SCIENCE,Vol. 5,No. 9,2010年09月,研究論文(学術雑誌)
  • Characterization of Natural Human Nucleotide-binding Oligomerization Domain Protein 1 (Nod1) Ligands from Bacterial Culture Supernatant for Elucidation of Immune Modulators in the Environment,Ambara R. Pradipta,Yukari Fujimoto,Mizuho Hasegawa,Naohiro Inohara,Koichi Fukase,JOURNAL OF BIOLOGICAL CHEMISTRY,AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC,Vol. 285,No. 31,p. 23607-23613,2010年07月,研究論文(学術雑誌)
  • Probe design and synthesis of Gal beta(1 -> 3)[NeuAc alpha(2 -> 6)]GlcNAc beta(1 -> 2)Man motif of N-glycan,Guang-ming Bao,Katsunori Tanaka,Kazuhiro Ikenaka,Koichi Fukase,BIOORGANIC & MEDICINAL CHEMISTRY,PERGAMON-ELSEVIER SCIENCE LTD,Vol. 18,No. 11,p. 3760-3766,2010年06月,研究論文(学術雑誌)
  • Key structures of bacterial peptidoglycan and lipopolysaccharide triggering the innate immune system of higher animals: Chemical synthesis and functional studies (vol 86, pg 322, 2010),Shoichi Kusumoto,Koichi Fukase,Tetsuo Shiba,PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES,JAPAN ACAD,Vol. 86,No. 5,p. 538-538,2010年05月
  • Key structures of bacterial peptidoglycan and lipopolysaccharide triggering the innate immune system of higher animals: Chemical synthesis and functional studies,Shoichi Kusumoto,Koichi Fukase,Tetsuo Shiba,PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES,JAPAN ACAD,Vol. 86,No. 4,p. 322-337,2010年04月
  • Structural prerequisites for endotoxic activity in the Limulus test as compared to cytokine production in mononuclear cells,T. Gutsmann,J. Howe,U. Z̈hringer,P. Garidel,A. B. Schromm,M. H.J. Koch,Y. Fujimoto,K. Fukase,I. Moriyon,G. Martínez-De-Tejada,K. Brandenburg,Innate Immunity,SAGE PUBLICATIONS LTD,Vol. 16,No. 1,p. 39-47,2010年02月,研究論文(学術雑誌)
  • Multimeric bivalent immunogens from recombinant tetanus toxin H-C fragment, synthetic hexasaccharides, and a glycopeptide adjuvant,Aileen F. G. Bongat,Rina Saksena,Roberto Adamo,Yukari Fujimoto,Zenyu Shiokawa,Dwight C. Peterson,Koichi Fukase,Willie F. Vann,Pavol Kovac,GLYCOCONJUGATE JOURNAL,SPRINGER,Vol. 27,No. 1,p. 69-77,2010年01月,研究論文(学術雑誌)
  • A New Strategy in Synthetic Biology: From Enzyme Inhibition, Natural Products Synthesis to PET Imaging by 6π-Azaelectrocyclization,The Chemical Records,Vol. 10,No. 2,p. 119-139,2010年,研究論文(学術雑誌)
  • SELF AND NONSELF RECOGNITION WITH BACTERIAL AND ANIMAL GLYCANS, SURVEYS BY SYNTHETIC CHEMISTRY,Yukari Fujimoto,Katsunori Tanaka,Atsushi Shimoyama,Koichi Fukase,METHODS IN ENZYMOLOGY, VOL 478: GLYCOMICS,ELSEVIER ACADEMIC PRESS INC,Vol. 478,No. C,p. 323-342,2010年,論文集(書籍)内論文
  • A Combined 6π-Azaelectrocyclization/Staudinger Approach to Protein & Cell Engineering: Noninvasive Tumor Targeting by N-Glycan-Engineered Lymphocytes,J. Carbohydr. Chem.,Vol. 29,No. 3,p. 118-132,2010年,研究論文(学術雑誌)
  • Widely Applicable Deprotection Method of 2,2,2-Trichloroethoxycarbonyl (Troc) Group Using Tetrabutylammonium Fluoride,Cheng-yuan Huang,Ning Wang,Katsumasa Fujiki,Yuji Otsuka,Masao Akamatsu,Yukari Fujimoto,Koichi Fukase,JOURNAL OF CARBOHYDRATE CHEMISTRY,TAYLOR & FRANCIS INC,Vol. 29,No. 6,p. 289-298,2010年,研究論文(学術雑誌)
  • Noninvasive Imaging of Dendrimer-Type N-Glycan Clusters: In Vivo Dynamics Dependence on Oligosaccharide Structure,Katsunori Tanaka,Eric R. O. Siwu,Kaori Minami,Koki Hasegawa,Satoshi Nozaki,Yousuke Kanayama,Koichi Koyama,Weihsu C. Chen,James C. Paulson,Yasuyoshi Watanabe,Koichi Fukase,ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,WILEY-V C H VERLAG GMBH,Vol. 49,No. 44,p. 8195-8200,2010年,研究論文(学術雑誌)
  • Asymmetric Synthesis of 14C-labeled L-Propargylglycine,Motohiro KUROSAWA,Katsunori TANAKA,Koichi FUKASE,Radioisotopes,Vol. 59,No. 12,p. 721-726,2010年
  • Nucleotide Oligomerization Binding Domain-Like Receptor Signaling Enhances Dendritic Cell-Mediated Cross-Priming In Vivo,Jumpei Asano,Hiroyuki Tada,Nobuyuki Onai,Taku Sato,Yasuo Horie,Yukari Fujimoto,Koichi Fukase,Akira Suzuki,Tak W. Mak,Toshiaki Ohteki,JOURNAL OF IMMUNOLOGY,AMER ASSOC IMMUNOLOGISTS,Vol. 184,No. 2,p. 736-745,2010年01月,研究論文(学術雑誌)
  • Renaissance of Traditional Organic Reactions under Microfluidic Conditions: A New Paradigm for Natural Products Synthesis,Katsunori Tanaka,Koichi Fukase,ORGANIC PROCESS RESEARCH & DEVELOPMENT,AMER CHEMICAL SOC,Vol. 13,No. 5,p. 983-990,2009年09月,研究論文(学術雑誌)
  • Lipopeptides from Staphylococcus aureus as Tlr2 Ligands: Prediction with mRNA Expression, Chemical Synthesis, and Immunostimulatory Activities,Yukari Fujimoto,Masahito Hashimoto,Maiko Furuyashiki,Mami Katsumoto,Tsukasa Seya,Yasuo Suda,Koichi Fukase,CHEMBIOCHEM,WILEY-V C H VERLAG GMBH,Vol. 10,No. 14,p. 2311-2315,2009年09月,研究論文(学術雑誌)
  • WaaA of the Hyperthermophilic Bacterium Aquifex aeolicus Is a Monofunctional 3-Deoxy-D-manno-oct-2-ulosonic Acid Transferase Involved in Lipopolysaccharide Biosynthesis,Uwe Mamat,Helgo Schmidt,Eva Munoz,Buko Lindner,Koichi Fukase,Anna Hanuszkiewicz,Jing Wu,Timothy C. Meredith,Ronald W. Woodard,Rolf Hilgenfeld,Jeroen R. Mesters,Otto Holst,JOURNAL OF BIOLOGICAL CHEMISTRY,AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC,Vol. 284,No. 33,p. 22248-22262,2009年08月,研究論文(学術雑誌)
  • Acid-mediated reactions under microfluidic conditions: A new strategy for practical synthesis of biofunctional natural products,Katsunori Tanaka,Koichi Fukase,BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY,BEILSTEIN-INSTITUT,Vol. 5,2009年08月,研究論文(学術雑誌)
  • Synthesis of crosslinked peptidoglycan fragments for investigation of their immunobiological functions,Yukari Fujimoto,Yasuko Konishi,Osamu Kubo,Mizuho Hasegawa,Naohiro Inohara,Koichi Fukase,TETRAHEDRON LETTERS,PERGAMON-ELSEVIER SCIENCE LTD,Vol. 50,No. 26,p. 3631-3634,2009年07月,研究論文(学術雑誌)
  • Traceless solid-phase synthesis of multiple sulfonamide-containing cyclic sulfides exploiting microwave irradiation,Kunio Saruta,Tsuyoshi Ogiku,Koichi Fukase,TETRAHEDRON LETTERS,PERGAMON-ELSEVIER SCIENCE LTD,Vol. 50,No. 30,p. 4364-4367,2009年07月,研究論文(学術雑誌)
  • Chemical N-Glycosylation by Asparagine under Integrated Microfluidic/Batch Conditions,Katsunori Tanaka,Takuya Miyagawa,Koichi Fukase,SYNLETT,GEORG THIEME VERLAG KG,Vol. 10, 1571-1574,No. 10,p. 1571-1574,2009年06月,研究論文(学術雑誌)
  • Characterization of N-terminal Structure of TLR2-activating Lipoprotein in Staphylococcus aureus,Kazuki Tawaratsumida,Maiko Furuyashiki,Mami Katsumoto,Yukari Fujimoto,Koichi Fukase,Yasuo Suda,Masahito Hashimoto,JOURNAL OF BIOLOGICAL CHEMISTRY,AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC,Vol. 284,No. 14,p. 9147-9152,2009年04月,研究論文(学術雑誌)
  • Practical Synthesis of a Man(1-4)GlcNTroc Fragment via Microfluidic -Mannosylation,Katsunori Tanaka,Yasutaka Mori,Koichi Fukase,JOURNAL OF CARBOHYDRATE CHEMISTRY,TAYLOR & FRANCIS INC,Vol. 28,No. 1,p. 1-11,2009年,研究論文(学術雑誌)
  • Library-directed Solution- and Solid-phase Synthesis of 2,4-Disubstituted Pyridines: One-pot Approach through 6 pi-Azaelectrocyclization,Taku Sakaguchi,Toyoharu Kobayashi,Sho Hatano,Hiroshi Tsuchikawa,Koichi Fukase,Katsunori Tanaka,Shigeo Katsumura,CHEMISTRY-AN ASIAN JOURNAL,WILEY-V C H VERLAG GMBH,Vol. 4,No. 10,p. 1573-1577,2009年,研究論文(学術雑誌)
  • Synthesis of a Sialic Acid Containing Complex-Type N-Glycan on a Solid Support,Katsunori Tanaka,Yohei Fujii,Hiroomi Tokimoto,Yasutaka Mori,Shin-ichi Tanaka,Guang-ming Bao,Eric R. O. Siwu,Aiko Nakayabu,Koichi Fukase,CHEMISTRY-AN ASIAN JOURNAL,WILEY-V C H VERLAG GMBH,Vol. 4,No. 4,p. 574-580,2009年,研究論文(学術雑誌)
  • First Positron Emission Tomography (PET) Imaging of Glycoproteins and Glycodendrimers by Efficient Chemical Labeling with [Ga-68]-DOTA,Katsunori Tanaka,Eric Richard Oktavianus Siwu,Kaori Minami,Koki Hasegawa,Yousuke Kanayama,Hiroshi Mizuma,Yasuhiro Wada,Yasuyoshi Watanabe,Koichi Fukase,GLYCOBIOLOGY,OXFORD UNIV PRESS INC,Vol. 18,No. 11,p. 981-981,2008年11月
  • Synthesis and Biological Activity of Helicobacter pylori Lipopolysaccharide Partial Structures,Atsushi Shimoyama,Yukari Fujimoto,Masato Iwata,Chika Kasamatsu,Yasuo Suda,Shoichi Kusumoto,Koichi Fukase,GLYCOBIOLOGY,OXFORD UNIV PRESS INC,Vol. 18,No. 11,p. 1003-1003,2008年11月
  • A New Catch-and-release Purification Method Using a Levulinyl Group as a Tag and Its Application to Oligosaccharide Synthesis,Minoru Izumi,Ritsu Okamoto,Mizuho Sato,Shuhei Nakajima,Naomichi Baba,Koichi Fukase,CHEMISTRY LETTERS,CHEMICAL SOC JAPAN,Vol. 37,No. 10,p. 1030-1031,2008年10月,研究論文(学術雑誌)
  • Site-Selective and Nondestructive Protein Labeling through Azaelectrocyclization-Induced Cascade Reactions,Katsunori Tanaka,Yohei Fujii,Koichi Fukase,CHEMBIOCHEM,WILEY-V C H VERLAG GMBH,Vol. 9,No. 15,p. 2392-2397,2008年10月,研究論文(学術雑誌)
  • Cross-tolerization between Nod1 and Nod2 signaling results in reduced refractoriness to bacterial infection in Nod2-deficient macrophages,Yun-Gi Kim,Jong-Hwan Park,Stephanie Daignault,Koichi Fukase,Gabriel Nunez,JOURNAL OF IMMUNOLOGY,AMER ASSOC IMMUNOLOGISTS,Vol. 181,No. 6,p. 4340-4346,2008年09月,研究論文(学術雑誌)
  • Recent advances in positron emission tomography (PET) imaging of biomolecules: From chemical labeling to cancer diagnostics,Katsunori Tanaka,Koichi Fukase,MINI-REVIEWS IN ORGANIC CHEMISTRY,BENTHAM SCIENCE PUBL LTD,Vol. 5,No. 3,p. 153-162,2008年08月,研究論文(学術雑誌)
  • Autophagic control of listeria through intracellular innate immune recognition in drosophila,Tamaki Yano,Shizuka Mita,Hiroko Ohmori,Yoshiteru Oshima,Yukari Fujimoto,Ryu Ueda,Haruhiko Takada,William E. Goldman,Koichi Fukase,Neal Silverman,Tamotsu Yoshimori,Shoichiro Kurata,NATURE IMMUNOLOGY,NATURE PUBLISHING GROUP,Vol. 9,No. 8,p. 908-916,2008年08月,研究論文(学術雑誌)
  • Synthesis of Rubrivivax gelatinosus Lipid A and Analogues for Investigation of the Structural Basis for Immunostimulating and Inhibitory Activities,Yoshiyuki Fukase,Yukari Fujimoto,Yo Adachi,Yasuo Suda,Shoichi Kusumoto,Koichi Fukase,Bulletin of the Chemical Society of Japan,The Chemical Society of Japan,Vol. 81,No. 7,p. 796-819,2008年07月15日,研究論文(学術雑誌)
  • Various human epithelial cells express functional Toll-like receptors, NOD1 and NOD2 to produce anti-microbial peptides, but not proinflammatory cytokines (vol 44, pg 3100, 2007),Akiko Uehara,Yukari Fujimoto,Koichi Fukase,Haruhiko Takada,MOLECULAR IMMUNOLOGY,PERGAMON-ELSEVIER SCIENCE LTD,Vol. 45,No. 12,p. 3505-3507,2008年07月
  • Meso-diaminopimelic acid and meso-lanthionine, amino acids specific to bacterial peptidoglycans, activate human epithelial cells through NOD1 (vol 177, pg 1796, 2006),A. Uehara,Y. Fujimoto,A. Kawasaki,S. Kusumoto,K. Fukase,H. Takada,JOURNAL OF IMMUNOLOGY,AMER ASSOC IMMUNOLOGISTS,Vol. 180,No. 11,p. 7774-7774,2008年06月
  • Efficient aldol condensation in aqueous biphasic system under microfluidic conditions,Katsunori Tanaka,Shinya Motomatsu,Koichi Koyama,Koichi Fukase,TETRAHEDRON LETTERS,PERGAMON-ELSEVIER SCIENCE LTD,Vol. 49,No. 12,p. 2010-2012,2008年03月,研究論文(学術雑誌)
  • Molecular cloning and functional characterization of porcine nucleotide-binding oligornerization domain-1 (NOD1) recognizing minimum agonists, meso-diaminopimelic acid and meso-lanthionine,Masanori Tohno,Tomoyuki Shimazu,Hisashi Aso,Akiko Uehara,Haruhiko Takada,Akiko Kawasaki,Yukari Fujimoto,Koichi Fukase,Tadao Saito,Haruki Kitazawa,MOLECULAR IMMUNOLOGY,PERGAMON-ELSEVIER SCIENCE LTD,Vol. 45,No. 6,p. 1807-1817,2008年03月,研究論文(学術雑誌)
  • Synthesis and Biofunctional Study of Bacterial Glycoconjugates,K. Fukase,Y. Fujimoto,A. Shimoyama,A. Kawasaki,A. R. Pradipta,Proceeding of the International Seminar on Chemistry,p. 46-53,2008年,研究論文(国際会議プロシーディングス)
  • Synthesis of Diaminopimelic Acid Containing Peptidoglycan Fragments and Tracheal Cytotoxin (TCT) and Investigation of Their Biological Functions,Akiko Kawasaki,Yukie Karasudani,Yuji Otsuka,Mizuho Hasegawa,Naohiro Inohara,Yukari Fujimoto,Koichi Fukase,CHEMISTRY-A EUROPEAN JOURNAL,WILEY-V C H VERLAG GMBH,Vol. 14,No. 33,p. 10318-10330,2008年,研究論文(学術雑誌)
  • A submicrogram-scale protocol for biomolecule-based PET imaging by rapid 6 pi-azaelectrocyclization: Visualization of sialic acid dependent circulatory residence of glycoproteins,Katsunori Tanaka,Tatsuro Masuyama,Koki Hasegawa,Tsuyoshi Tahara,Hiroshi Mizuma,Yasuhiro Wada,Yasuyoshi Watanabe,Koichi Fukase,ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,WILEY-V C H VERLAG GMBH,Vol. 47,No. 1,p. 102-105,2008年,研究論文(学術雑誌)
  • Differential activation of human TLR4 by Escherichia coli and Shigella flexneri 2a lipopolysaccharide: Combined effects of lipid A acylation state and TLR4 polymorphisms on signaling,Prasad Rallabhandi,Agnes Awomoyi,Karen E. Thomas,Armelle Phalipon,Yukari Fujimoto,Koichi Fukase,Shoichi Kusumoto,Nilofer Qureshi,Marcelo B. Sztein,Stefanie N. Vogel,JOURNAL OF IMMUNOLOGY,AMER ASSOC IMMUNOLOGISTS,Vol. 180,No. 2,p. 1139-1147,2008年01月,研究論文(学術雑誌)
  • PET (positron emission tomography) imaging of biomolecules using metal-DOTA complexes: a new collaborative challenge by chemists, biologists, and physicians for future diagnostics and exploration of in vivo dynamics,Katsunori Tanaka,Koichi Fukase,ORGANIC & BIOMOLECULAR CHEMISTRY,ROYAL SOC CHEMISTRY,Vol. 6,No. 5,p. 815-828,2008年,研究論文(学術雑誌)
  • A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kappa B activation,Mizuho Hasegawa,Yukari Fujimoto,Peter C. Lucas,Hiroyasu Nakano,Koichi Fukase,Gabriel Nunez,Naohiro Inohara,EMBO JOURNAL,WILEY,Vol. 27,No. 2,p. 373-383,2008年01月,研究論文(学術雑誌)
  • Synthesis of immunoregulatory Helicobacter pylori lipopolysaccharide partial structures,Yukari Fujimoto,Masato Iwata,Noriko Imakita,Atsushi Shimoyama,Yasuo Suda,Shoichi Kusumoto,Koichi Fukase,TETRAHEDRON LETTERS,PERGAMON-ELSEVIER SCIENCE LTD,Vol. 48,No. 37,p. 6577-6581,2007年09月,研究論文(学術雑誌)
  • Acceleration of Cu(I)-mediated Huisgen 1,3-dipolar cycloaddition by histidine derivatives,Katsunori Tanaka,Chika Kageyama,Koichi Fukase,TETRAHEDRON LETTERS,PERGAMON-ELSEVIER SCIENCE LTD,Vol. 48,No. 37,p. 6475-6479,2007年09月,研究論文(学術雑誌)
  • Highly efficient α-salylation by virtue of fixed dipole effects of N-phthalyl group: application to continuous flow synthesis of α(2-3)- and α(2-6)-Neu5Ac-Gal motifs by microreactor.,J. Carbohydr. Chem.,Vol. 26,No. 7-9,p. 369-394,2007年09月,研究論文(学術雑誌)
  • ORGN 980-Synthesis of immunostimulating peptidoglycan fragments recognized by intracellular receptor,Yukari Fujimoto,Akiko Kawasaki,Atsushi Shimoyama,Naohiro Inohara,Koichi Fukase,ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY,AMER CHEMICAL SOC,Vol. 234,p. 113-130,2007年08月,研究論文(学術雑誌)
  • Nod1/RICK and TLR signaling regulate chemokine and antimicrobial innate immune responses in mesothelial cells,Jong-Hwan Park,Yun-Gi Kim,Michael Shaw,Thirumala-Devi Kanneganti,Yukari Fujimoto,Koichi Fukase,Naohiro Inohara,Gabriel Nunez,JOURNAL OF IMMUNOLOGY,AMER ASSOC IMMUNOLOGISTS,Vol. 179,No. 1,p. 514-521,2007年07月,研究論文(学術雑誌)
  • Crystal structures of human MD-2 and its complex with antiendotoxic lipid IVa,Umeharu Ohto,Koichi Fukase,Kensuke Miyake,Yoshinori Satow,SCIENCE,AMER ASSOC ADVANCEMENT SCIENCE,Vol. 316,No. 5831,p. 1632-1634,2007年06月,研究論文(学術雑誌)
  • Various human epithelial cells express functional Toll-like receptors, NOD1 and NOD2 to produce anti-microbial peptides, but not proinflammatory cytokines,Akiko Uehara,Yukari Fujimoto,Koichi Fukase,Haruhiko Takada,MOLECULAR IMMUNOLOGY,PERGAMON-ELSEVIER SCIENCE LTD,Vol. 44,No. 12,p. 3100-3111,2007年05月,研究論文(学術雑誌)
  • Evidence of immunostimulating lipoprotein existing in the natural lipoteichoic acid fraction,Masahito Hashimoto,Maiko Furuyashiki,Ryoko Kaseya,Yuka Fukada,Mai Akimaru,Kazue Aoyama,Toshiomi Okuno,Toshihide Tamura,Teruo Kirikae,Fumiko Kirikae,Nobutaka Eiraku,Hirofumi Morioka,Yukari Fujimoto,Koichi Fukase,Katsuhiro Takashige,Yoichiro Moriya,Shoichi Kusumoto,Yasuo Suda,INFECTION AND IMMUNITY,AMER SOC MICROBIOLOGY,Vol. 75,No. 4,p. 1926-1932,2007年04月,研究論文(学術雑誌)
  • A role of lipophilic peptidoglycan-related molecules in induction of Nod1-mediated immune responses,Mizuho Hasegawa,Akiko Kawasaki,Kangkang Yang,Yukari Fujimoto,Junya Masumoto,Eefjan Breukink,Gabriel Nunez,Koichi Fukase,Naohiro Inohara,JOURNAL OF BIOLOGICAL CHEMISTRY,AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC,Vol. 282,No. 16,p. 11757-11764,2007年04月,研究論文(学術雑誌)
  • Differential modulation of nods signaling pathways by fatty acids in human colonic epithelial HCT116 cells,Ling Zhao,Myung-Ja Kwon,Shurong Huang,Joo Y. Lee,Koichi Fukase,Naohiro Inohara,Daniel H. Hwang,JOURNAL OF BIOLOGICAL CHEMISTRY,AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC,Vol. 282,No. 16,p. 11618-11628,2007年04月,研究論文(学術雑誌)
  • Inhibition of lipid A-mediated type I interferon induction by Bactericidal/permeability-increasing protein (BPI),Masahiro Azuma,Aya Matsuo,Yukari Fujimoto,Koichi Fukase,Kaoru Hazeki,Osamu Hazeki,Misako Matsumoto,Tsukasa Seya,BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,ACADEMIC PRESS INC ELSEVIER SCIENCE,Vol. 354,No. 2,p. 574-578,2007年03月,研究論文(学術雑誌)
  • Efficient procedure for reductive opening of sugar 4,6-O-benzylidene acetals in a microfluidic system,Katsunori Tanaka,Koichi Fukase,SYNLETT,GEORG THIEME VERLAG KG,No. 1,p. 164-166,2007年01月,研究論文(学術雑誌)
  • Chemical synthesis of peptidoglycan fragments for elucidation of the immunostimulating mechanism,Yukari Fujimoto,Seiichi Inamura,Akiko Kawasaki,Zenyu Shiokawa,Atsushi Shimoyama,Takashi Hashimoto,Shoichi Kusumoto,Koichi Fukase,JOURNAL OF ENDOTOXIN RESEARCH,SAGE PUBLICATIONS LTD,Vol. 13,No. 3,p. 189-196,2007年
  • Large-scale synthesis of immunoactivating natural product, pristane, by continuous microfluidic dehydration as the key step,Katsunori Tanaka,Shinya Motomatsu,Koichi Koyama,Shin-ichi Tanaka,Koichi Fukase,ORGANIC LETTERS,AMER CHEMICAL SOC,Vol. 9,No. 2,p. 299-302,2007年01月,研究論文(学術雑誌)
  • Recombinant soluble forms of extracellular TLR4 domain and MD-2 inhibit lipopolysaccharide binding on cell surface and dampen lipopolysaccharide-induced pulmonary inflammation in mice,Hiroaki Mitsuzawa,Chiaki Nishitani,Naoki Hyakushima,Takeyuki Shimizu,Hitomi Sano,Norio Matsushima,Koichi Fukase,Yoshio Kuroki,JOURNAL OF IMMUNOLOGY,AMER ASSOC IMMUNOLOGISTS,Vol. 177,No. 11,p. 8133-8139,2006年12月,研究論文(学術雑誌)
  • Synthesis and biological activities of biscarboxymethyl lipid A analogues,Mikayo Kataoka,Masaya Hashimoto,Yasuo Suda,Shoichi Kusumoto,Koichi Fukase,HETEROCYCLES,PERGAMON-ELSEVIER SCIENCE LTD,Vol. 69,No. 1,p. 395-+,2006年12月,研究論文(学術雑誌)
  • Synthesis of lipid A monosaccharide analogues containing acidic amino acid: Exploring the structural basis for the endotoxic and antagonistic activities,Masao Akamatsu,Yukarl Fujimoto,Mikayo Kataoka,Yasuo Suda,Shoichi Kusumoto,Koichi Fukase,BIOORGANIC & MEDICINAL CHEMISTRY,PERGAMON-ELSEVIER SCIENCE LTD,Vol. 14,No. 19,p. 6759-6777,2006年10月,研究論文(学術雑誌)
  • Virulence factors of Yersinia pestis are overcome by a strong lipopolysaccharide response,Sara W. Montminy,Naseema Khan,Sara McGrath,Mitchell J. Walkowicz,Fiona Sharp,Joseph E. Conlon,Koichi Fukase,Shoichi Kusumoto,Charles Sweet,Kensuke Miyake,Shizuo Akira,Robert J. Cotter,Jon D. Goguen,Egil Lien,NATURE IMMUNOLOGY,NATURE PUBLISHING GROUP,Vol. 7,No. 10,p. 1066-1073,2006年10月,研究論文(学術雑誌)
  • Mannose-binding lectin augments the uptake of lipid A, Staphylococcus aureus, and Escherichia coli by Kupffer cells through increased cell surface expression of scavenger receptor A,Kei Ono,Chiaki Nishitani,Hiroaki Mitsuzawa,Takeyuki Shimizu,Hitomi Sano,Hiroshi Suzuki,Tatsuhiko Kodama,Nobuhiro Fujii,Koichi Fukase,Koichi Hirata,Yoshio Kuroki,JOURNAL OF IMMUNOLOGY,AMER ASSOC IMMUNOLOGISTS,Vol. 177,No. 8,p. 5517-5523,2006年10月,研究論文(学術雑誌)
  • Sarcoidosis and NOD1 variation with impaired recognition of intracellular Propionibacterium acnes.,Tsuyoshi Tanabe,Ikuo Ishige,Yoshimi Suzuki,Yukie Aita,Asuka Furukawa,Yuki Ishige,Keisuke Uchida,Takashige Suzuki,Tamiko Takemura,Soichiro Ikushima,Masaru Oritsu,Tetsuji Yokoyama,Yukari Fujimoto,Koichi Fukase,Naohiro Inohara,Gabriel Nunez,Yoshinobu Eishi,Biochimica et biophysica acta,Vol. 1762,No. 9,p. 794-801,2006年09月,研究論文(学術雑誌)
  • Sarcoidosis and NOD1 variation with impaired recognition of intracellular Propionibacterium acnes,Tsuyoshi Tanabe,Ikuo Ishige,Yoshimi Suzuki,Yukie Aita,Asuka Furukawa,Yuki Ishige,Keisuke Uchida,Takashige Suzuki,Tamiko Takemura,Soichiro Ikushima,Masaru Oritsu,Tetsuji Yokoyama,Yukari Fujimoto,Koichi Fukase,Naohiro Inohara,Gabriel Nunez,Yoshinobil Eishi,BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE,ELSEVIER SCIENCE BV,Vol. 1762,No. 9,p. 794-801,2006年09月,研究論文(学術雑誌)
  • Differential release and distribution of Nod1 and Nod2 immunostimulatory molecules among bacterial species and environments,Mizuho Hasegawa,Kangkang Yang,Masahito Hashimoto,Jong-Hwan Park,Yun-Gi Kim,Yukari Fujimoto,Gabriel Nunez,Koichi Fukase,Naohiro Inohara,JOURNAL OF BIOLOGICAL CHEMISTRY,AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC,Vol. 281,No. 39,p. 29054-29063,2006年09月,研究論文(学術雑誌)
  • Meso-diaminopimelic acid and meso-lanthionine, amino acids specific to bacterial peptidoglycans, activate human epithelial cells through NOD1,Akiko Uehara,Yukari Fujimoto,Akiko Kawasaki,Shoichi Kusumoto,Koichi Fukase,Haruhiko Takada,JOURNAL OF IMMUNOLOGY,AMER ASSOC IMMUNOLOGISTS,Vol. 177,No. 3,p. 1796-1804,2006年08月,研究論文(学術雑誌)
  • Toll-like Receptors, NOD1, and NOD2 in Oral Epithelial Cells,Y. Sugawara,A. Uehara,Y. Fujimoto,S. Kusumoto,K. Fukase,K. Shibata,S. Sugawara,T. Sasano,H. Takada,Journal of Dental Research,SAGE Publications,Vol. 85,No. 6,p. 524-529,2006年06月,研究論文(学術雑誌)
  • Regulatory roles for MD-2 and TLR4 in ligand-induced receptor clustering,Makiko Kobayashi,Shin-ichiroh Saitoh,Natsuko Tanimura,Koichiro Takahashi,Kiyoshi Kawasaki,Masahiro Nishijima,Yukari Fujimoto,Koichi Fukase,Sachiko Akashi-Takamura,Kensuke Miyake,JOURNAL OF IMMUNOLOGY,AMER ASSOC IMMUNOLOGISTS,Vol. 176,No. 10,p. 6211-6218,2006年05月,研究論文(学術雑誌)
  • A Synthetic Peptidoglycan Fragment as a Competitive Inhibitor of the Melanization Cascade,Ji Won Park,Byung-Rok Je,Shunfu Piao,Seiichi Inamura,Yukari Fujimoto,Koichi Fukase,Shoichi Kusumoto,Kenneth Söderhäll,Nam-Chul Ha,Bok Luel Lee,Journal of Biological Chemistry,American Society for Biochemistry & Molecular Biology (ASBMB),Vol. 281,No. 12,p. 7747-7755,2006年03月24日,研究論文(学術雑誌)
  • Biologically active lipid A antagonist embedded in a multilayered polyelectrolyte architecture,Sophie C. Gangloff,Guy Ladam,Valérie Dupray,Kochi Fukase,Klaus Brandenburg,Moncef Guenounou,Pierre Schaaf,Jean-Claude Voegel,Nadia Jessel,Biomaterials,Elsevier BV,Vol. 27,No. 9,p. 1771-1777,2006年03月,研究論文(学術雑誌)
  • Nod1 acts as an intracellular receptor to stimulate chemokine production and neutrophil recruitment in vivo,Junya Masumoto,Kangkang Yang,Sooryanarayana Varambally,Mizuho Hasegawa,Scott A. Tomlins,Su Qiu,Yukari Fujimoto,Akiko Kawasaki,Simon J. Foster,Yasuo Horie,Tak W. Mak,Gabriel Núñez,Arul M. Chinnaiyan,Koichi Fukase,Naohiro Inohara,Journal of Cell Biology,Vol. 172,No. 3,p. 203-213,2006年01月30日,研究論文(学術雑誌)
  • Synthesis and bioactivity of fluorescence- and biotin-labeled lipid a analogues for investigation of recognition mechanism in innate immunity,Yukari Fujimoto,Eiji Kimura,Shuichi Murata,Shoichi Kusumoto,Koichi Fukase,Tetrahedron Letters,Vol. 47,No. 4,p. 539-543,2006年01月23日,研究論文(学術雑誌)
  • Nod1 acts as an intracellular receptor to stimulate chemokine production and neutrophil recruitment in vivo,Junya Masumoto,Kangkang Yang,Sooryanarayana Varambally,Mizuho Hasegawa,Scott A. Tomlins,Su Qiu,Yukari Fujimoto,Akiko Kawasaki,Simon J. Foster,Yasuo Horie,Tak W. Mak,Gabriel Núñez,Arul M. Chinnaiyan,Koichi Fukase,Naohiro Inohara,Journal of Experimental Medicine,Rockefeller University Press,Vol. 203,No. 1,p. 203-213,2006年01月23日,研究論文(学術雑誌)
  • Synthesis of peptidoglycan fragments and evaluation of their biological activity.,Seiichi Inamura,Yukari Fujimoto,Akiko Kawasaki,Zenyu Shiokawa,Eva Woelk,Holger Heine,Buko Lindner,Naohiro Inohara,Shoichi Kusumoto,Koichi Fukase,Organic & biomolecular chemistry,Vol. 4,No. 2,p. 232-42,2006年01月21日,研究論文(学術雑誌)
  • Synthesis of endotoxic principle of bacterial lipopolysaccharide and its recognition by innate immune system of hosts,Shoichi Kusumoto,Koichi Fukase,CHEMICAL RECORD,WILEY-V C H VERLAG GMBH,Vol. 6,No. 6,p. 333-343,2006年,研究論文(学術雑誌)
  • Highly efficient sialylation towards α(2-3)- and α(2-6)-Neu5Ac- Gal synthesis: Significant 'fixed dipole effect' of N-phthalyl group on α-selectivity,Katsunori Tanaka,Takashi Goi,Koichi Fukase,Synlett,No. 19,p. 2958-2962,2005年12月01日,研究論文(学術雑誌)
  • New deprotection method of the 2,2,2-trichloroethoxycarbonyl (Troc) group with (BU<inf>3</inf>Sn)<inf>2</inf>,Hiroomi Tokimoto,Koichi Fukase,Tetrahedron Letters,PERGAMON-ELSEVIER SCIENCE LTD,Vol. 46,No. 40,p. 6831-6832,2005年10月03日,研究論文(学術雑誌)
  • Human peptidoglycan recognition protein S is an effector of neutrophil-mediated innate immunity,Hyun Cho Ju,Iain P. Fraser,Koichi Fukase,Shoichi Kusumoto,Yukari Fujimoto,Gregory L. Stahl,R. Alan B. Ezekowitz,Blood,Vol. 106,No. 7,p. 2551-2558,2005年10月,研究論文(学術雑誌)
  • Oligosaccharide synthesis by affinity separation based on molecular recognition between podand ether and ammonium ion,Koichi Fukase,Mamoru Takashina,Yumiko Hori,Daizo Tanaka,Katsunori Tanaka,Shoichi Kusumoto,Synlett,GEORG THIEME VERLAG KG,No. 15,p. 2342-2346,2005年09月19日,研究論文(学術雑誌)
  • Highly β-selective mannosylation towards Manβ1-4GlcNAc synthesis: TMSB(C<sub>6</sub>F<sub>5</sub>)<sub>4</sub> as a Lewis acid/cation trap catalyst,Shin-Ichi Tanaka,Mamoru Takashina,Hiroomi Tokimoto,Yukari Fujimoto,Katsunori Tanaka,Koichi Fukase,Synlett,No. 15,p. 2325-2328,2005年09月19日,研究論文(学術雑誌)
  • Upregulation of PGRPs by chemically synthesized pathogen-associated molecular patterns via Toll-like receptors, NOD1 and NOD2 in oral epithelial cells,Akiko Uehara,Yumiko Sugawara,Shoichiro Kurata,Yukari Fujimoto,Koichi Fukase,Shoichi Kusumoto,Takashi Sasano,Kenichiro Shibata,Shunji Sugawara,Haruhiko Takada,International Congress Series,Vol. 1284,p. 163-168,2005年09月,研究論文(学術雑誌)
  • Dendritic cell maturation induced by muramyl dipeptide (MDP) derivatives: monoacylated MDP confers TLR2/TLR4 activation.,Junji Uehori,Koichi Fukase,Takashi Akazawa,Satoshi Uematsu,Shizuo Akira,Kenji Funami,Masashi Shingai,Misako Matsumoto,Ichiro Azuma,Kumao Toyoshima,Shoichi Kusumoto,Tsukasa Seya,Journal of immunology (Baltimore, Md. : 1950),AMER ASSOC IMMUNOLOGISTS,Vol. 174,No. 11,p. 7096-103,2005年06月01日,研究論文(学術雑誌)
  • Chemically synthesized pathogen-associated molecular patterns increase the expression of peptidoglycan recognition proteins via Toll-like receptors, NOD1 and NOD2 in human oral epithelial cells,A Uehara,Y Sugawara,S Kurata,Y Fujimoto,K Fukase,S Kusumoto,Y Satta,T Sasano,S Sugawara,H Takada,CELLULAR MICROBIOLOGY,BLACKWELL PUBLISHING LTD,Vol. 7,No. 5,p. 675-686,2005年05月,研究論文(学術雑誌)
  • Chlorotrimethylsilane as a mild and effective source of acid catalyst in reductive benzylation,Minoru Izumi,Koichi Fukase,Chemistry Letters,CHEMICAL SOC JAPAN,Vol. 34,No. 4,p. 594-595,2005年04月,研究論文(学術雑誌)
  • Stereoselective glycosylation using the long-range effect of a [2-(4-phenylbenzyl)oxycarbonyl]benzoyl group,Hiroomi Tokimoto,Yukari Fujimoto,Koichi Fukase,Shoichi Kusumoto,Tetrahedron Asymmetry,Elsevier BV,Vol. 16,No. 2,p. 441-447,2005年01月24日,研究論文(学術雑誌)
  • Synthesis of lipid A and its analogues for investigation of the structural basis for their bioactivity.,Yukari Fujimoto,Yo Adachi,Masao Akamatsu,Yoshiyuki Fukase,Mikayo Kataoka,Yasuo Suda,Koichi Fukase,Shoichi Kusumoto,Journal of endotoxin research,Vol. 11,No. 6,p. 341-7,2005年,研究論文(学術雑誌)
  • Physicochemical characterization of carboxymethyl lipid A derivatives in relation to biological activity,Ulrich Seydel,Andra B. Schromm,Lore Brade,Sabine Gronow,Jörg Andrä,Mareike Müller,Michel H. J. Koch,Koichi Fukase,Mikayo Kataoka,Masaya Hashimoto,Shoichi Kusumoto,Klaus Brandenburg,FEBS Journal,Wiley,Vol. 272,No. 2,p. 327-340,2005年01月,研究論文(学術雑誌)
  • Muramyldipeptide and diaminopimelic acid-containing desmuramylpeptides in combination with chemically synthesized Toll-like receptor agonists synergistically induced production of interleukin-8 in a NOD2- and NOD1-dependent manner, respectively, in human,A. Uehara,S. Yang,Y. Fujimoto,K. Fukase,S. Kusumoto,K. Shibata,S. Sugawara,H. Takada,Cellular Microbiology,Wiley,Vol. 7,No. 1,p. 53-61,2004年08月04日,研究論文(学術雑誌)
  • Ligand-dependent Toll-like receptor 4 (TLR4)-oligomerization is directly linked with TLR4-signaling,Shin-ichiroh Saitoh,Sachiko Akashi,Takenao Yamada,Natsuko Tanimura,Fumi Matsumoto,Koichi Fukase,Shoichi Kusumoto,Atsushi Kosugi,Kensuke Miyake,Journal of Endotoxin Research,SAGE Publications,Vol. 10,No. 4,p. 257-260,2004年08月01日,研究論文(学術雑誌)
  • Combinational clustering of receptors following stimulation by bacterial products determines lipopolysaccharide responses,Martha TRIANTAFILOU,Klaus BRANDENBURG,Shoichi KUSUMOTO,Koichi FUKASE,Alan MACKIE,Ulrich SEYDEL,Kathy TRIANTAFILOU,Biochemical Journal,Portland Press Ltd.,Vol. 381,No. 2,p. 527-536,2004年07月15日,研究論文(学術雑誌)
  • Aggregates Are the Biologically Active Units of Endotoxin,Mareike Mueller,Buko Lindner,Shoichi Kusumoto,Koichi Fukase,Andra B. Schromm,Ulrich Seydel,Journal of Biological Chemistry,American Society for Biochemistry & Molecular Biology (ASBMB),Vol. 279,No. 25,p. 26307-26313,2004年06月18日,研究論文(学術雑誌)
  • Lipid A antagonist, lipid IVa, is distinct from lipid A in interaction with Toll-like receptor 4 (TLR4)-MD-2 and ligand-induced TLR4 oligomerization,S.-i. Saitoh,International Immunology,Oxford University Press (OUP),Vol. 16,No. 7,p. 961-969,2004年05月24日,研究論文(学術雑誌)
  • Monomeric and Polymeric Gram-Negative Peptidoglycan but Not Purified LPS Stimulate the Drosophila IMD Pathway,Takashi Kaneko,William E Goldman,Peter Mellroth,Håkan Steiner,Koichi Fukase,Shoichi Kusumoto,William Harley,Alvin Fox,Douglas Golenbock,Neal Silverman,Immunity,Elsevier BV,Vol. 20,No. 5,p. 637-649,2004年05月,研究論文(学術雑誌)
  • Different shapes of LPS induce the formation of different receptor clusters,M Triantafilou,K Brandenburg,S Kusumoto,K Fukase,A Mackie,U Seydel,K Triantafilou,PROCEEDINGS OF THE 6TH WORLD CONGRESS ON TRAUMA, SHOCK, INFLAMMATION AND SEPSIS- PATHOPHYSIOLOGY, IMMUNE CONSEQUENCES AND THERAPY,MEDIMOND PUBLISHING CO,p. 205-210,2004年,研究論文(国際会議プロシーディングス)
  • Solid-Phase Synthesis of Indol-2-ones by Microwave-Assisted Radical ­Cyclization,Koichi Fukase,Hisashi Akamatsu,Shoichi Kusumoto,Synlett,Georg Thieme Verlag KG,Vol. 8, 87-98/,,No. 6,p. 1049-1053,2004年,研究論文(学術雑誌)
  • NMR conformational analysis of biosynthetic precursor-type lipid A: monomolecular state and supramolecular assembly,Masato Oikawa,Tetsuya Shintaku,Naohiro Fukuda,Harald Sekljic,Yoshiyuki Fukase,Hiroaki Yoshizaki,Koichi Fukase,Shoichi Kusumoto,Organic & Biomolecular Chemistry,Royal Society of Chemistry (RSC),Vol. 2,No. 24,p. 3557-3557,2004年,研究論文(学術雑誌)
  • Human Peptidoglycan Recognition Protein-L Is anN-Acetylmuramoyl-L-alanine Amidase,Zheng-Ming Wang,Xinna Li,Ross R. Cocklin,Minhui Wang,Mu Wang,Koichi Fukase,Seiichi Inamura,Shoichi Kusumoto,Dipika Gupta,Roman Dziarski,Journal of Biological Chemistry,American Society for Biochemistry & Molecular Biology (ASBMB),Vol. 278,No. 49,p. 49044-49052,2003年12月05日,研究論文(学術雑誌)
  • A dominant role of Toll-like receptor 4 in the signaling of apoptosis in bacteria-faced macrophages.,Rudolf Haase,Carsten J Kirschning,Andreas Sing,Percy Schröttner,Koichi Fukase,Shoichi Kusumoto,Hermann Wagner,Jürgen Heesemann,Klaus Ruckdeschel,Journal of immunology (Baltimore, Md. : 1950),AMER ASSOC IMMUNOLOGISTS,Vol. 171,No. 8,p. 4294-303,2003年10月15日,研究論文(学術雑誌)
  • Lipopolysaccharide interaction with cell surface Toll-like receptor 4-MD-2: higher affinity than that with MD-2 or CD14.,Sachiko Akashi,Shin-ichiroh Saitoh,Yasutaka Wakabayashi,Takane Kikuchi,Noriaki Takamura,Yoshinori Nagai,Yutaka Kusumoto,Koichi Fukase,Shoichi Kusumoto,Yoshiyuki Adachi,Atsushi Kosugi,Kensuke Miyake,The Journal of experimental medicine,ROCKEFELLER UNIV PRESS,Vol. 198,No. 7,p. 1035-42,2003年10月06日,研究論文(学術雑誌)
  • Cell activation by monosaccharide lipid A analogues utilizing Toll-like receptor 4.,Riyoko Tamai,Yasuyuki Asai,Masahito Hashimoto,Koichi Fukase,Shoichi Kusumoto,Hideharu Ishida,Makoto Kiso,Tomohiko Ogawa,Immunology,BLACKWELL PUBLISHING LTD,Vol. 110,No. 1,p. 66-72,2003年09月,研究論文(学術雑誌)
  • Solid-phase synthesis of a phytoalexin elicitor pentasaccharide using a 4-azido-3-chlorobenzyl group as the key for temporary protection and catch-and-release purification,Kenji Egusa,Shoichi Kusumoto,Koichi Fukase,European Journal of Organic Chemistry,Wiley,Vol. 2003,No. 17,p. 3435-3445,2003年08月25日,研究論文(学術雑誌)
  • An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid,Mathias Chamaillard,Masahito Hashimoto,Yasuo Horie,Junya Masumoto,Su Qiu,Lisa Saab,Yasunori Ogura,Akiko Kawasaki,Koichi Fukase,Shoichi Kusumoto,Miguel A. Valvano,Simon J. Foster,Tak W. Mak,Gabriel Nuñez,Naohiro Inohara,Nature Immunology,NATURE PUBLISHING GROUP,Vol. 4,No. 7,p. 702-707,2003年07月01日,研究論文(学術雑誌)
  • Endotoxic and immunobiological activities of a chemically synthesized lipid A of Helicobacter pylori strain 206-1,Tomohiko Ogawa,Yasuyuki Asai,Yasuhiro Sakai,Masato Oikawa,Koichi Fukase,Yasuo Suda,Shoichi Kusumoto,Toshihide Tamura,FEMS Immunology and Medical Microbiology,ELSEVIER SCIENCE BV,Vol. 36,No. 1-2,p. 1-7,2003年05月15日,研究論文(学術雑誌)
  • Synthesis and biological activities of lipid A analogs possessing β-glycosidic linkage at 1-position,Koichi Fukase,Atsushi Ueno,Yoshiyuki Fukase,Masato Oikawa,Yasuo Suda,Shoichi Kusumoto,Bulletin of the Chemical Society of Japan,The Chemical Society of Japan,Vol. 76,No. 3,p. 485-500,2003年03月,研究論文(学術雑誌)
  • Host Recognition of Bacterial Muramyl Dipeptide Mediated through NOD2,Naohiro Inohara,Yasunori Ogura,Ana Fontalba,Olga Gutierrez,Fernando Pons,Javier Crespo,Koichi Fukase,Seiichi Inamura,Shoichi Kusumoto,Masahito Hashimoto,Simon J. Foster,Anthony P. Moran,Jose L. Fernandez-Luna,Gabriel Nuñez,Journal of Biological Chemistry,American Society for Biochemistry & Molecular Biology (ASBMB),Vol. 278,No. 8,p. 5509-5512,2003年02月21日,研究論文(学術雑誌)
  • Structural basis for endotoxic and antagonistic activities: investigation with novel synthetic lipid A analogs.,Shoichi Kusumoto,Koichi Fukase,Yoshiyuki Fukase,Mikayo Kataoka,Hiroaki Yoshizaki,Kenjiro Sato,Masato Oikawa,Yasuo Suda,Journal of endotoxin research,MANEY PUBLISHING,Vol. 9,No. 6,p. 361-6,2003年,研究論文(学術雑誌)
  • Reactivity switching on solid support: solid-phase synthesis of tertiary amines by reduction of tertiary amides with LiAlH4,Hisashi Akamatsu,Shoichi Kusumoto,Koichi Fukase,Tetrahedron Letters,Elsevier BV,Vol. 43,No. 49,p. 8867-8869,2002年12月,研究論文(学術雑誌)
  • Chemical synthesis of cyclodextrins by using intramolecular glycosylation,Masahiro Wakao,Koichi Fukase,Shoichi Kusumoto,Journal of Organic Chemistry,AMER CHEMICAL SOC,Vol. 67,No. 23,p. 8182-8190,2002年11月15日,研究論文(学術雑誌)
  • New efficient route for solid-phase synthesis of benzimidazole derivatives,Hisashi Akamatsu,Koichi Fukase,Shoichi Kusumoto,Journal of Combinatorial Chemistry,AMER CHEMICAL SOC,Vol. 4,No. 5,p. 475-483,2002年09月,研究論文(学術雑誌)
  • Synthetic chemistry and function of bacterial cell surface glycoconjugates,Shoichi Kusumoto,Koichi Fukase,Masato Oikawa,Yasuo Suda,Journal of the Chinese Chemical Society,CHINESE CHEM SOC,Vol. 49,No. 4,p. 453-458,2002年,研究論文(国際会議プロシーディングス)
  • A direct continuous spectrophotometric assay for glycosidases with 3-nitro-2-pyridyl glycosides by tautomerization of 2-hydroxy-3-nitropyridine,Seung Jin Ma,Jun Hiratake,Yasushi Nakai,Minoru Izumi,Koichi Fukase,Shoichi Kusumoto,Kanzo Sakata,Analytical Biochemistry,ACADEMIC PRESS INC ELSEVIER SCIENCE,Vol. 302,No. 2,p. 291-297,2002年,研究論文(学術雑誌)
  • TMSCl as a mild and effective source of acidic catalysis in fischer glycosidation and use of propargyl glycoside for anomeric protection,Minoru Izumi,Koichi Fukase,Shoichi Kusumoto,Bioscience, Biotechnology and Biochemistry,TAYLOR & FRANCIS LTD,Vol. 66,No. 1,p. 211-214,2002年,研究論文(学術雑誌)
  • Solid-phase synthesis of oligosaccharides using novel alkyne-type linkers: Selection of reactive sites on the support by Sonogashira reaction,Minoru Izumi,Koichi Fukase,Shoichi Kusumoto,Synlett,GEORG THIEME VERLAG KG,Vol. 19,1409/,,No. 9,p. 1409-1416,2002年,研究論文(学術雑誌)
  • New efficient route for synthesis of lipid A by using affinity separations (Nov, pg 1693, 2001),Y Fukase,SQ Zhang,K Iseki,M Oikawa,K Fukase,S Kusumoto,SYNLETT,GEORG THIEME VERLAG KG,No. 12,p. 2004-2004,2001年12月
  • Synthetic study of peptidoglycan partial structures. Synthesis of tetrasaccharide and octasaccharide fragments,Seiichi Inamura,Koichi Fukase,Shoichi Kusumoto,Tetrahedron Letters,PERGAMON-ELSEVIER SCIENCE LTD,Vol. 42,No. 43,p. 7613-7616,2001年10月22日,研究論文(学術雑誌)
  • Conformational study of a tetraacyl biosynthetic precursor of lipid A by NMR,M. Oikawa,T. Shintaku,H. Yoshizaki,K. Fukase,S. Adachi,K. Lee,S. Kusumoto,Bulletin of the Chemical Society of Japan,Vol. 74,No. 8,p. 1455-1461,2001年08月,研究論文(学術雑誌)
  • Chemoenzymatic synthesis of a trisaccharide-serine conjugate, gal(β1-3)gal(β1-4)xyl(β1-o)-l-ser, use of galactosyl fluoride as a donor for transglycosylation,K. Fukase,T. Yasukochi,S. Kusumoto,Bulletin of the Chemical Society of Japan,CHEMICAL SOC JAPAN,Vol. 74,No. 6,p. 1123-1128,2001年06月,研究論文(学術雑誌)
  • First Total Synthesis of the Re-Type Lipopolysaccharide This work was supported by the Research for the Future Program (No. 97L00502) from the Japan Society for the Promotion of Science. H.Y. is grateful for a JSPS Research Fellowship for Young Scientists (No. 1241) from the Japan Society for the Promotion of Science. The authors are grateful to Mr. Seiji Adachi for his skillful measurement of NMR spectra.,Hiroaki Yoshizaki,Naohiro Fukuda,Kenjiro Sato,Masato Oikawa,Koichi Fukase,Yasuo Suda,Shoichi Kusumoto,Angewandte Chemie (International ed. in English),Vol. 40,No. 8,p. 1475-1480,2001年04月17日,研究論文(学術雑誌)
  • First total synthesis of the Re-type lipopolysaccharide,Hiroaki Yoshizaki,Naohiro Fukuda,Kenjiro Sato,Masato Oikawa,Koichi Fukase,Yasuo Suda,Shoichi Kusumoto,Angewandte Chemie - International Edition,WILEY-V C H VERLAG GMBH,Vol. 40,No. 8,p. 1475-1480,2001年04月,研究論文(学術雑誌)
  • Synthesis of [<sup>3</sup>H]-labeled bioactive lipid a analogs and their use for detection of lipid A-binding proteins on murine macrophages,Koichi Fukase,Teruo Kirikae,Fumiko Kirikae,Wen Chi Liu,Masato Oikawa,Yasuo Suda,Motohiro Kurosawa,Yoshiyuki Fukase,Hiroaki Yoshizaki,Shoichi Kusumoto,Bulletin of the Chemical Society of Japan,CHEMICAL SOC JAPAN,Vol. 74,No. 11,p. 2189-2197,2001年,研究論文(学術雑誌)
  • New efficient route for synthesis of lipid A by using affinity separation,Y. Fukase,S. Q. Zhang,K. Iseki,M. Oikawa,K. Fukase,S. Kusumoto,Synlett,GEORG THIEME VERLAG KG,No. 11,p. 1693-1698,2001年,研究論文(学術雑誌)
  • Human MD-2 confers on mouse toll-like receptor 4 species-specific lipopolysaccharide recognition,Sachiko Akashi,Yoshinori Nagai,Hirotaka Ogata,Masato Oikawa,Koichi Fukase,Shoichi Kusumoto,Kiyoshi Kawasaki,Masahiro Nishijima,Shinichiro Hayashi,Masao Kimoto,Kensuke Miyake,International Immunology,Oxford University Press,Vol. 13,No. 12,p. 1595-1599,2001年,研究論文(学術雑誌)
  • A new catch-and-release purification method using a 4-azido-3-chlorobenzyl group,K. Egusa,S. Kusumoto,K. Fukase,Synlett,GEORG THIEME VERLAG KG,No. 6,p. 777-780,2001年,研究論文(学術雑誌)
  • Synthesis based on affinity separation (SAS): Separation of products having barbituric acid tag from untagged compounds by using hydrogen bond interaction,San Qi Zhang,Koichi Fukase,Minoru Izumi,Yoshiyuki Fukase,Shoichi Kusumoto,Synlett,GEORG THIEME VERLAG KG,No. 5,p. 590-596,2001年,研究論文(学術雑誌)
  • Lipopolysaccharide-binding protein-mediated interaction of lipid A from different origin with phospholipid membranes: Invited lecture,T. Gutsmann,A. B. Schromm,M. H.J. Koch,S. Kusumoto,K. Fukase,M. Oikawa,U. Seydel,K. Brandenburg,Physical Chemistry Chemical Physics,ROYAL SOC CHEMISTRY,Vol. 2,No. 20,p. 4521-4528,2000年10月15日,研究論文(学術雑誌)
  • Synthesis of Helicobacter pylori lipid A and its analogue using p-(trifluoromethyl)benzyl protecting group,Yasuhiro Sakai,Masato Oikawa,Hiroaki Yoshizaki,Tomohiko Ogawa,Yasuo Suda,Koichi Fukase,Shoichi Kusumoto,Tetrahedron Letters,PERGAMON-ELSEVIER SCIENCE LTD,Vol. 41,No. 35,p. 6843-6847,2000年08月26日,研究論文(学術雑誌)
  • Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide,Egil Lien,Terry K. Means,Holger Heine,Atsutoshi Yoshimura,Shoichi Kusumoto,Koichi Fukase,Matthew J. Fenton,Masato Oikawa,Nilofer Qureshi,Brian Monks,Robert W. Finberg,Robin R. Ingalls,Douglas T. Golenbock,Journal of Clinical Investigation,AMER SOC CLINICAL INVESTIGATION INC,Vol. 105,No. 4,p. 497-504,2000年02月,研究論文(学術雑誌)
  • Intrinsic conformation of lipid A is responsible for agonistic and antagonistic activity,Ulrich Seydel,Masato Oikawa,Koichi Fukase,Shoichi Kusumoto,Klaus Brandenburg,European Journal of Biochemistry,WILEY-BLACKWELL,Vol. 267,No. 10,p. 3032-3039,2000年,研究論文(学術雑誌)
  • Conformational studies on a unique bis-sulfated glycolipid using NMR spectroscopy and molecular dynamics simulations,Naoko Iida-Tanaka,Koichi Fukase,Hiroaki Utsumi,Ineo Ishizuka,European Journal of Biochemistry,BLACKWELL SCIENCE LTD,Vol. 267,No. 23,p. 6790-6797,2000年,研究論文(学術雑誌)
  • Stereoselective glycosylation and oligosaccharide synthesis on solid support using a 4-azido-3-chlorobenzyl group for temporary protection,Kenji Egusa,Koichi Fukase,Yoshihiko Nakai,Shoichi Kusumoto,Synlett,GEORG THIEME VERLAG,No. 1,p. 27-32,2000年,研究論文(学術雑誌)
  • New methodology for high throughput solution-phase synthesis: Affinity purification by using crown ether and ammonium ion interaction,San qi Zhang,Koichi Fukase,Shoichi Kusumoto,Tetrahedron Letters,PERGAMON-ELSEVIER SCIENCE LTD,Vol. 40,No. 42,p. 7479-7483,1999年10月15日,研究論文(学術雑誌)
  • Nitropyridyl glycosides: New glycosyl donors for enzymatic transglycosylation,Takashi Yasukochi,Chikako Inaba,Koichi Fukase,Shoichi Kusumoto,Tetrahedron Letters,PERGAMON-ELSEVIER SCIENCE LTD,Vol. 40,No. 36,p. 6585-6589,1999年09月03日,研究論文(学術雑誌)
  • 3-Nitro-2-pyridyl glycoside as donor for chemical glycosylation and its application to chemoenzymatic synthesis of oligosaccharide,Takashi Yasukochi,Koichi Fukase,Shoichi Kusumoto,Tetrahedron Letters,PERGAMON-ELSEVIER SCIENCE LTD,Vol. 40,No. 36,p. 6591-6593,1999年09月03日,研究論文(学術雑誌)
  • Synthesis of<sup>13</sup>C-labeled biosynthetic precursor of lipid A and its analogue with shorter acyl chains,Masato Oikawa,Tetsuya Shintaku,Harald Sekljic,Koichi Fukase,Shoichi Kusumoto,Bulletin of the Chemical Society of Japan,CHEMICAL SOC JAPAN,Vol. 72,No. 8,p. 1857-1867,1999年08月,研究論文(学術雑誌)
  • A divergent synthesis of lipid A and its chemically stable unnatural analogues,Wen Chi Liu,Masato Oikawa,Koichi Fukase,Yasuo Suda,Shoichi Kusumoto,Bulletin of the Chemical Society of Japan,CHEMICAL SOC JAPAN,Vol. 72,No. 6,p. 1377-1385,1999年06月,研究論文(学術雑誌)
  • Propargyloxycarbonyl and propargyl groups for novel protection of amino, hydroxy, and carboxy functions,Y. Kukase,K. Fukase,S. Kusumoto,Tetrahedron Letters,PERGAMON-ELSEVIER SCIENCE LTD,Vol. 40,No. 6,p. 1169-1170,1999年02月05日,研究論文(学術雑誌)
  • LPS-dependent changes in the expression of 57 KDa and 53 KDa cell membrane proteins without participation of CD14,Teruo Kirikae,Fumiko Kirikae,Hiroki Iwai,Nilofer Qureshi,Koichi Fukase,Shoichi Kusumoto,Masayasu Nakano,Innate Immunity,Vol. 5,No. 1-2,p. 62-65,1999年,研究論文(学術雑誌)
  • A biophysical approach towards an understanding of endotoxin-induced signal transduction,A. B. Schromm,K. Brandenburg,R. Blunck,K. Fukase,S. Kusumoto,E. Th Rietschel,U. Seydel,Innate Immunity,Vol. 5,No. 1-2,p. 41-45,1999年,研究論文(学術雑誌)
  • New synthesis and conformational analysis of lipid A: Biological activity and supramolecular assembly,Koichi Fukase,Masato Oikawa,Yasuo Suda,Wen Chi Liu,Yoshiyuki Fukase,Tetsuya Shintaku,Harald Sekljic,Hiroaki Yoshizaki,Shoichi Kusumoto,Innate Immunity,Vol. 5,No. 1-2,p. 46-51,1999年,研究論文(学術雑誌)
  • A typical bacterial ornithine-containing lipid N(α)-(D)-[3-(hexadecanoyloxy)hexadecanoyl]-ornithine is a strong stimulant for macrophages and a useful adjuvant,Yohko Kawai,Yoji Nakagawa,Tohei Matuyama,Kiyoko Akagawa,Kazutoshi Itagawa,Koichi Fukase,Shoichi Kusumoto,Masahiro Nishijima,Ikuya Yano,FEMS Immunology and Medical Microbiology,Vol. 23,No. 1,p. 67-73,1999年01月,研究論文(学術雑誌)
  • Novel dehydrative glycosylation by using acid anhydride and TMSClO<inf>4</inf>,Masahiro Wakao,Yoshihiko Nakai,Koichi Fukase,Shoichi Kusumoto,Chemistry Letters,CHEMICAL SOC JAPAN,No. 1,p. 27-28,1999年,研究論文(学術雑誌)
  • LPS-dependent changes in the expression of 57 kDa and 53 kDa cell membrane proteins without participation of CD14,Teruo Kirikae,Fumiko Kirikae,Hiroki Iwai,Nilofer Qureshi,Koichi Fukase,Shoichi Kusumoto,Masayasu Nakano,Journal of Endotoxin Research,MANEY PUBLISHING LTD,Vol. 5,No. 1-2,p. 62-65,1999年,研究論文(国際会議プロシーディングス)
  • A novel oxidatively removable linker and its application to α-selective solid-phase oligosaccharide synthesis on a macroporous polystyrene support,Koichi Fukase,Yoshihiko Nakai,Kenji Egusa,John A. Porco,Shoichi Kusumoto,Synlett,GEORG THIEME VERLAG,No. 7,p. 1074-1078,1999年,研究論文(学術雑誌)
  • Novel molecular clamp method for anomeric stereocontrol of glycosylation,Masahiro Wakao,Koichi Fukase,Shoichi Kusumoto,Synlett,GEORG THIEME VERLAG,No. 12,p. 1911-1914,1999年,研究論文(学術雑誌)
  • New synthesis and conformational analysis of lipid A: Biological activity and supramolecular assembly,Koichi Fukase,Masato Oikawa,Yasuo Suda,Wen Chi Liu,Yoshiyuki Fukase,Tetsuya Shintaku,Harald Sekljic,Hiroaki Yoshizaki,Shoichi Kusumoto,Journal of Endotoxin Research,MANEY PUBLISHING LTD,Vol. 5,No. 1-2,p. 46-51,1999年,研究論文(国際会議プロシーディングス)
  • A biophysical approach towards an understanding of endotoxin-induced signal transduction,A. B. Schromm,K. Brandenburg,R. Blunck,K. Fukase,S. Kusumoto,E. Th Rietschel,U. Seydel,Journal of Endotoxin Research,MANEY PUBLISHING LTD,Vol. 5,No. 1-2,p. 41-45,1999年,研究論文(国際会議プロシーディングス)
  • Divergent synthesis and biological activities of lipid A analogues of shorter acyl chains,Koichi Fukase,Yoshiyuki Fukase,Masato Oikawa,Wen Chi Liu,Yasuo Suda,Shoichi Kusumoto,Tetrahedron,PERGAMON-ELSEVIER SCIENCE LTD,Vol. 54,No. 16,p. 4033-4050,1998年04月,研究論文(国際会議プロシーディングス)
  • Mild but efficient methods for stereoselective glycosylation with thioglycosides: Activation by [N-phenylselenophthalimide-Mg(ClO<inf>4</inf>)<inf>2</inf>] and [PhIO-Mg(ClO<inf>4</inf>)<inf>2</inf>],Koichi Fukase,Yoshihiko Nakai,Takeshi Kanoh,Shoichi Kusumoto,Synlett,GEORG THIEME VERLAG,No. 1,p. 84-86,1998年01月,研究論文(学術雑誌)
  • Enzymatic Synthesis of 4-Methylumbelliferyl Glycosides of Trisaccharide and Core Tetrasaccharide, Gal(β1-3)Gal(β1-4)Xyl and GlcA(β1-3)Gal(β1-3)Gal(β-4)Xyl, Corresponding to the Linkage Region of Proteoglycans,Takashi Yasukochi,Koichi Fukase,Yasuo Suda,Keiichi Takagaki,Masahiko Endo,Shoichi Kusumoto,Bulletin of the Chemical Society of Japan,Chemical Society of Japan,Vol. 70,No. 11,p. 2719-2725,1997年11月,研究論文(学術雑誌)
  • Enzymatic preparation of (S)-3-hydroxytetradecanoic acid and synthesis of unnatural analogues of lipid A containing the (S)-acid,Wen Chi Liu,Masato Oikawa,Koichi Fukase,Yasuo Suda,Hendig Winarno,Saeko Mori,Masahito Hashimoto,Shoichi Kusumoto,Bulletin of the Chemical Society of Japan,Vol. 70,No. 6,p. 1441-1450,1997年06月,研究論文(学術雑誌)
  • New efficient synthesis of a biosynthetic precursor of lipid A,Masato Oikawa,Akira Wada,Hiroaki Yoshizaki,Koichi Fukase,Shoichi Kusumoto,Bulletin of the Chemical Society of Japan,Vol. 70,No. 6,p. 1435-1440,1997年06月,研究論文(学術雑誌)
  • 4-Azido-3-chlorobenzyl Ether, New Protection for Hydroxy Functions,Kenji Egusa,Koichi Fukase,Shoichi Kusumoto,Synlett,GEORG THIEME VERLAG,Vol. 1997,No. 6,p. 675-676,1997年,研究論文(学術雑誌)
  • Novel oxidatively removable protecting groups and linkers for solid-phase synthesis of oligosaccharides,Koichi Fukase,Kenji Egusa,Yoshihiko Nakai,Shoichi Kusumoto,Molecular Diversity,KLUWER ACADEMIC PUBL,Vol. 2,No. 4,p. 182-188,1997年,研究論文(学術雑誌)
  • Chemical synthesis of bacterial glycoconjugates in relation to their immunostimulating activity,S Kusumoto,K Fukase,Y Suda,M Oikawa,JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN,SOC SYNTHETIC ORGANIC CHEM JPN,Vol. 54,No. 11,p. 976-987,1996年11月,研究論文(学術雑誌)
  • Chemoenzymatic synthesis of Gal(β1-3)Gal(β1-4)Xyl(β)-L-Ser and Gal(β1-3)Gal(β1-4)Xyl(β)-MU by the use of β-D-galactosidase,Koichi Fukase,Takashi Yasukochi,Yasuo Suda,Masao Yoshida,Shoichi Kusumoto,Tetrahedron Letters,PERGAMON-ELSEVIER SCIENCE LTD,Vol. 37,No. 37,p. 6763-6766,1996年09月09日,研究論文(学術雑誌)
  • p-Nitrophenyl group for anomeric protection of oligosaccharides, selective oxidative cleavage via p-acetamidophenyl glycosides,Koichi Fukase,Takashi Yasukochi,Yoshihiko Nakai,Shoichi Kusumoto,Tetrahedron Letters,PERGAMON-ELSEVIER SCIENCE LTD,Vol. 37,No. 19,p. 3343-3344,1996年05月06日,研究論文(学術雑誌)
  • A novel method for stereoselective glycosidation with thioglycosides: Promotion by hypervalent iodine reagents prepared from PhIO and various acids,Koichi Fukase,Ikuko Kinoshita,Takeshi Kanoh,Yoshihiko Nakai,Atsushi Hasuoka,Shoichi Kusumoto,Tetrahedron,PERGAMON-ELSEVIER SCIENCE LTD,Vol. 52,No. 11,p. 3897-3904,1996年03月11日,研究論文(学術雑誌)
  • Synthesis and biological activity of a model disaccharide containing a key unit in heparin for binding to platelets,Yasuo Suda,Karyn Bird,Takaaki Shiyama,Shuhei Koshida,Dalila Marques,Koichi Fukase,Michael Sobel,Shoichi Kusumoto,Tetrahedron Letters,PERGAMON-ELSEVIER SCIENCE LTD,Vol. 37,No. 7,p. 1053-1056,1996年02月12日,研究論文(学術雑誌)
  • Synthesis of neoglycoproteins containing 5-O-phosphorylated kdomonosaccharide, 4-O- and 5-O-phosphorylated α-kd(2 6)-2-acetamido-2-deoxy-β-d-glucopyranosyl disaccharide residues,Harald Sekljic,Paul Kosma,Johannes Bartek,Koichi Fukase,Shoichi Kusumoto,Helmut Brade,Innate Immunity,Vol. 3,No. 2,p. 151-164,1996年,研究論文(学術雑誌)
  • Detection of UDP-D-xylose:α-D-xyloside α1 → 3xylosyltransferase activity in human hepatoma cell line HepG2,Satsuki Minamida,Kyoko Aoki,Shunji Natsuka,Kaoru Omichi,Koichi Fukase,Shoichi Kusumoto,Sumihiro Hase,Journal of Biochemistry,Oxford University Press,Vol. 120,No. 5,p. 1002-1006,1996年,研究論文(学術雑誌)
  • Synthesis of neoglycoproteins containing 5-O-phosphorylated Kdomonosaccharide, 4-O- and 5-O-phosphorylated α-Kdo→(2 6)-2-acetamido-2-deoxy-β-D-glucopyranosyl disaccharide residues,Harald Sekljic,Paul Kosma,Johannes Bartek,Koichi Fukase,Shoichi Kusumoto,Helmut Brade,Journal of Endotoxin Research,CHURCHILL LIVINGSTONE,Vol. 3,No. 2,p. 151-164,1996年,研究論文(学術雑誌)
  • Regioselective Reductive Opening of 4,6-O-Benzylidene Acetals of Glucose or Glucosamine Derivatives by BH<inf>3</inf>·Me<inf>2</inf>NH - BF<inf>3</inf>-OEt<inf>2</inf>,Masato Oikawa,Wen Chi Liu,Yoshihiko Nakai,Shuhei Koshida,Koichi Fukase,Shoichi Kusumoto,Synlett,GEORG THIEME VERLAG,Vol. 1996,No. 12,p. 1179-1180,1996年,研究論文(学術雑誌)
  • Synthetic Study of a Bioactive <sup>3</sup>H-Labeled Analogue of Lipid A,Koichi Fukase,Ikuko Kinoshita,Yasuo Suda,Yutaka Aoki,Wen Chi Liu,Masato Oikawa,Motohiro Kurosawa,Ulrich Zähringer,Ulrich Seydel,Ernst Th Rietschel,Shoichi Kusumoto,Synlett,GEORG THIEME VERLAG,Vol. 1996,No. 3,p. 252-254,1996年,研究論文(学術雑誌)
  • Synthetic route for <sup>14</sup>C-labeling of a bioactive lipid a analogue,Koichi Fukase,Yutaka Aoki,Ikuko Kinoshita,Yasuo Suda,Motohiro Kurosawa,Ulrich Zähringer,Ernst Th Rietschel,Shoichi Kusumoto,Tetrahedron Letters,PERGAMON-ELSEVIER SCIENCE LTD,Vol. 36,No. 47,p. 8645-8648,1995年11月20日,研究論文(学術雑誌)
  • Synthesis of an analog of biosynthetic precursor Ia of lipid A by an improved method: a novel antagonist containing four (S)-3-hydroxy fatty acids,Koichi Fukase,Wen Chi Liu,Yasuo Suda,Masato Oikawa,Akira Wada,Saeko Mori,Arthur J. Ulmer,Ernst Th Rietschel,Shoichi Kusumoto,Tetrahedron Letters,PERGAMON-ELSEVIER SCIENCE LTD,Vol. 36,No. 41,p. 7455-7458,1995年10月09日,研究論文(学術雑誌)
  • A stereoselective glycosidation using thioglycosides, activation by combination of N-bromosuccinimide and strong acid salts,Koichi Fukase,Atsushi Hasuoka,Ikuko Kinoshita,Yutaka Aoki,Shoichi Kusumoto,Tetrahedron,PERGAMON-ELSEVIER SCIENCE LTD,Vol. 51,No. 17,p. 4923-4932,1995年04月,研究論文(学術雑誌)
  • Molecular and structural requirements of a lipoteichoic acid from Enterococcus hirae ATCC 9790 for cytokine-inducing, antitumor, and antigenic activities,H. Takada,Y. Kawabata,R. Arakaki,S. Kusumoto,K. Fukase,Y. Suda,T. Yoshimura,S. Kokeguchi,K. Kato,T. Komuro,N. Tanaka,M. Saito,T. Yoshida,M. Sato,S. Kotani,Infection and Immunity,Vol. 63,No. 1,p. 57-65,1995年,研究論文(学術雑誌)
  • Synthesis and purification by HPLC of des-O-acyl partial structures of Escherichia coli Re lipopolysaccharide,K. Fukase,M. Kurosawa,S. Kusumoto,Journal of Endotoxin Research,Vol. 1,No. 3,p. 149-163,1994年09月,研究論文(学術雑誌)
  • Functional fluorescence labeling of carbohydrates and its use for preparation of neoglycoconjugates,Koichi Fukase,Hideo Nakayama,Motohiro Kurosawa,Toshiki Ikegaki,Takeshi Kanoh,Sumihiro Hase,Shoichi Kusumoto,Journal of Carbohydrate Chemistry,Vol. 13,No. 5,p. 715-736,1994年07月01日,研究論文(学術雑誌)
  • Identification of Trisaccharide Xylal→3Xyla1-&gt;3Glc in Human Urine,Jun Ichi Toyota,Koichi Fukase,Shoichi Kusumoto,Sumihiro Hase,Bioscience, Biotechnology, and Biochemistry,TAYLOR & FRANCIS LTD,Vol. 58,No. 3,p. 567-569,1994年,研究論文(学術雑誌)
  • Synthetic study of lipoteichoic acid of gram positive bacteria. II. Synthesis of the proposed fundamental structure of Enterococcus hirae lipoteichoic acid,K. Fukase,T. Yoshimura,S. Kotani,S. Kusumoto,Bulletin of the Chemical Society of Japan,CHEMICAL SOC JAPAN,Vol. 67,No. 2,p. 473-482,1994年,研究論文(学術雑誌)
  • FUNCTIONAL FLUORESCENT LABELING OF CARBOHYDRATES AND ITS APPLICATION TO LIPOPOLYSACCHARIDE,K FUKASE,H NAKAYAMA,M KUROSAWA,T IKEGAKI,S KUSUMOTO,GLYCOCONJUGATE JOURNAL,CHAPMAN HALL LTD,Vol. 10,No. 4,p. 326-326,1993年08月
  • SMALL-SCALE SOLID-PHASE O-GLYCOPEPTIDE SYNTHESIS OF LINEAR AND CYCLIZED HEXAPEPTIDES FROM BLOOD-CLOTTING FACTOR-IX CONTAINING O-(ALPHA-D-XYL-1-]3-ALPHA-D-XYL-1-]3-BETA-D-GLC)-L-SER,KB REIMER,M MELDAL,S KUSUMOTO,K FUKASE,K BOCK,JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1,ROYAL SOC CHEMISTRY,No. 8,p. 925-932,1993年04月,研究論文(学術雑誌)
  • A novel method for activation of thioglycosides, combination of N-bromosuccinimide and triflic acid salts,Fukase Koichi,Hasuoka Atsushi,Kusumoto Shoichi,Tetrahedron Letters,PERGAMON-ELSEVIER SCIENCE LTD,Vol. 34,No. 13,p. 2187-2190,1993年03月26日,研究論文(学術雑誌)
  • Synthesis and immunoreactivity of poly(acrylamide) copolymers containing C-3- and C-7-modified, carboxyl-reduced, 4-O- and 5-O-phosphorylated K,Paul Kosma,Martina Strobl,Leopold März,Shoichi Kusumoto,Koichi Fukase,Lore Brade,Helmut Brade,Carbohydrate Research,Vol. 238,No. C,p. 93-107,1993年01月15日,研究論文(学術雑誌)
  • Small-scale solid-phase O-glycopeptide synthesis of linear and cyclized hexapeptides from blood-clotting factor IX containing O-(α-D-Xyl-1→3- α-D-Xyl-1→3-β-D-Glc)-L-Ser,Kerry B. Reimer,Morten Meldal,Shoichi Kusumoto,Koichi Fukase,Klus Bock,Journal of the Chemical Society, Perkin Transactions 1,No. 8,p. 925-932,1993年,研究論文(学術雑誌)
  • Iodosobenzene-triflic anhydride as an efficient promoter for glycosidation reaction using thioglycosides as donors,Koichi Fukase,Atsushi Hasuoka,Ikuko Kinoshita,Shoichi Kusumoto,Tetrahedron Letters,PERGAMON-ELSEVIER SCIENCE LTD,Vol. 33,No. 47,p. 7165-7168,1992年11月17日,研究論文(学術雑誌)
  • Effects of Dehydroalanine on Peptide Conformations,Darryl Erik Palmer,Christian Pattaroni,Kenichi Nunami,Raj K. Chadha,Murray Goodman,Tateaki Wakamiya,Koichi Fukase,Shingo Horimoto,Manabu Kitazawa,Hiroshi Fujita,Akira Kubo,Tetsuo Shiba,Journal of the American Chemical Society,Vol. 114,No. 14,p. 5634-5642,1992年07月01日,研究論文(学術雑誌)
  • CHEMICAL SYNTHESIS OF LIPOTEICHOIC ACID, BIOLOGICAL ACTIVE GLYCOCONJUGATE OF GRAM-POSITIVE BACTERIAL-CELL SURFACE,S KUSUMOTO,K FUKASE,JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN,SOC SYNTHETIC ORGANIC CHEM JPN,Vol. 50,No. 5,p. 401-409,1992年05月,研究論文(学術雑誌)
  • Synthetic study on peptide antibiotic nisin. V. Total synthesis of nisin,K. Fukase,M. Kitazawa,A. Sano,K. Shimbo,S. Horimoto,H. Fujita,A. Kubo,T. Wakamiya,T. Shiba,Bulletin of the Chemical Society of Japan,Vol. 65,No. 8,p. 2227-2240,1992年,研究論文(学術雑誌)
  • Synthetic study on lipoteichoic acid of gram positive bacteria. I. Synthesis of proposed fundamental structure of Streptococcus pyogenes lipoteichoic acid,K. Fukase,T. Matsumoto,N. Ito,T. Yoshimura,S. Kotani,S. Kusumoto,Bulletin of the Chemical Society of Japan,CHEMICAL SOC JAPAN,Vol. 65,No. 10,p. 2643-2654,1992年,研究論文(学術雑誌)
  • Synthesis of new serine-linked oligosaccharides in blood-clotting factors VII and IX and protein Z. The synthesis of O-α-D-xylopyranosyl-(1→3)-D-glucopyranose, O-α-D-xylopyranosyl-(1→3)-O-α-D-xylopyranosyl-(1→3)-D-glucopyranos e, and their conjugates with serine,K. Fukase,S. Hase,T. Ikenaka,S. Kusumoto,Bulletin of the Chemical Society of Japan,CHEMICAL SOC JAPAN,Vol. 65,No. 2,p. 436-445,1992年,研究論文(学術雑誌)
  • 4-Pivaloylaminobenzyl ether, a new temporary protection for hydroxyl functions,Koichi Fukase,Takuya Yoshimura,Manabu Hashida,Shoichi Kusumoto,Tetrahedron Letters,PERGAMON-ELSEVIER SCIENCE LTD,Vol. 32,No. 32,p. 4019-4022,1991年08月05日,研究論文(学術雑誌)
  • Application of 4-azidobenzyl group to protection of hydroxyl functions,Koichi Fukase,Manabu Hashida,Shoichi Kusumoto,Tetrahedron Letters,PERGAMON-ELSEVIER SCIENCE LTD,Vol. 32,No. 29,p. 3557-3558,1991年07月15日,研究論文(学術雑誌)
  • Synthesis of allyl 3-deoxy-D-manno-2-octulopyranosidic acid 4- and 5-phosphates,K. Fukase,T. Kamikawa,Y. Iwai,T. Shiba,E. T. Rietschell,S. Kusumoto,Bulletin of the Chemical Society of Japan,CHEMICAL SOC JAPAN,Vol. 64,No. 11,p. 3267-3273,1991年,研究論文(学術雑誌)
  • Synthetic study on peptide antibiotic nisin. III. Synthesis of ring C,K. Fukase,M. Kitazawa,T. Wakamiya,T. Shiba,Bulletin of the Chemical Society of Japan,Vol. 63,No. 6,p. 1838-1840,1990年,研究論文(学術雑誌)
  • Synthetic study on peptide antibiotic nisin. IV. Synthesis of ring D-E,K. Fukase,Y. Oda,A. Kubo,T. Wakamiya,T. Shiba,Bulletin of the Chemical Society of Japan,Vol. 63,No. 6,p. 1758-1763,1990年,研究論文(学術雑誌)
  • 4-NITROBENZYL GROUP FOR PROTECTION OF HYDROXYL FUNCTIONS,K FUKASE,H TANAKA,S TORII,S KUSUMOTO,TETRAHEDRON LETTERS,PERGAMON-ELSEVIER SCIENCE LTD,Vol. 31,No. 3,p. 389-392,1990年,研究論文(学術雑誌)
  • Interactive nmr and computer simulation studies of lanthionine‐ring structures,D. E. Palmer,D. F. Mierke,C. Pattaroni,M. Goodman,T. Wakamiya,K. Fukase,M. Kitazawa,H. Fujita,T. Shiba,Biopolymers,Vol. 28,No. 1,p. 397-408,1989年01月,研究論文(学術雑誌)
  • Lanthiopeptin, a new peptide antibiotic. Production, isolation and properties of lanthiopeptin,Nobuaki Naruse,Osamu Tenmyo,Koji Tomita,Masataka Konishi,Takeo Miyaki,Hiroshi Kawaguchi,Koichi Fukase,Tateaki Wakamiya,Tetsuo Shiba,The Journal of Antibiotics,Vol. 42,No. 6,p. 837-845,1989年,研究論文(学術雑誌)
  • Total synthesis of peptide antibiotic nisin,Koichi Fukase,Manabu Kitazawa,Akihiko Sano,Kuniaki Shimbo,Hiroshi Fujita,Shingo Horimoto,Tateaki Wakamiya,Tetsuo Shiba,Tetrahedron Letters,Vol. 29,No. 7,p. 795-798,1988年,研究論文(学術雑誌)
  • Lanthiopeptin, a new peptide effective against herpes simplex virus: Structural determination and comparison with Ro 09-0198, an immunopotentiating peptide,Tateaki Wakamiya,Koichi Fukase,Nobuaki Naruse,Masataka Konishi,Tetsuo Shiba,Tetrahedron Letters,Vol. 29,No. 37,p. 4771-4772,1988年,研究論文(学術雑誌)
  • Chemistry of lanthionine peptides,T. Shiba,T. Wakamiya,K. Fukase,Biopolymers,Vol. 25,No. SUPPL.,1986年,研究論文(学術雑誌)
  • Synthetic study on peptide antibiotic nisin. II. The synthesis of ring B,K. Fukase,T. Wakamiya,T. Shiba,Bulletin of the Chemical Society of Japan,Vol. 59,No. 8,p. 2505-2508,1986年,研究論文(学術雑誌)
  • An Improved Synthesis ofthreo-3-Methyl-D-cysteine,Tateaki Wakamiya,Koichi Fukase,Kuniaki Shimbo,Tetsuo Shiba,Bulletin of the Chemical Society of Japan,The Chemical Society of Japan,Vol. 56,No. 5,p. 1559-1560,1983年05月,研究論文(学術雑誌)

MISC

  • 極長鎖GM3ガングリオシドを介したTLR4活性化がメタボリックシンドロームを発症させる,狩野裕考,新田昂大,郷慎司,藤居真優,樺山一哉,下山敦史,深瀬浩一,安藤弘宗,石田秀治,鈴木明身,井ノ口仁一,日本糖質学会年会要旨集,Vol. 37th,2021年06月14日
  • Recent Advances in the Chemical Biology of N-Glycans,Asuka Shirakawa,Yoshiyuki Manabe,Koichi Fukase,MOLECULES,MDPI,Vol. 26,No. 4,2021年02月,書評論文,書評,文献紹介等
  • アルファ線核医学治療のための薬剤開発の考察(その3),矢野 恒夫,長谷川 功紀,角永 悠一郎,樺山 一哉,小田 敬,上野 悟史,蜂須賀 暁子,平林 容子,深瀬 浩一,医薬品医療機器レギュラトリーサイエンス,(一財)医薬品医療機器レギュラトリーサイエンス財団,Vol. 50,No. 12,p. 749-763,2019年12月
  • ガングリオシドのアシル鎖構造によるToll-like receptor 4活性化制御メカニズム,狩野 裕考,新田 昂大,藤居 真優,樺山 一哉,下山 敦史,深瀬 浩一,Sonnino Sandro,鈴木 明身,井ノ口 仁一,エンドトキシン・自然免疫研究,日本エンドトキシン・自然免疫研究会,Vol. 22,No. 0,p. 1-7,2019年11月
  • アルファ線核医学治療の薬剤開発―臨床試験に向けた安全性基準構築への考察―,長谷川功紀,佐藤達彦,蜂須賀暁子,深瀬浩一,平林容子,矢野恒夫,素粒子論研究・電子版(Web),Vol. 29,2019年10月15日
  • がん研究における女性研究者(第6回) がん細胞型アミノ酸トランスポーターを標的とした短寿命アルファ線核医学治療薬の開発(Women scientists in cancer research Investigation of novel drug for alpha-emitting nuclear medicine targeting to cancer specific amino acid transporter),兼田 加珠子,真鍋 良幸,下山 敦史,樺山 一哉,金井 好克,豊嶋 厚史,深瀬 浩一,篠原 厚,日本癌学会総会記事,日本癌学会,Vol. 78回,p. SS-3,2019年09月
  • Preface,Koichi Fukase,TRENDS IN GLYCOSCIENCE AND GLYCOTECHNOLOGY,GAKUSHIN PUBL CO,Vol. 31,No. 181,p. SE1-SE1,2019年07月
  • アルファ線核医学治療のための薬剤開発の考察(その2),矢野 恒夫,長谷川 功紀,佐藤 達彦,蜂須賀 暁子,深瀬 浩一,平林 容子,医薬品医療機器レギュラトリーサイエンス,(一財)医薬品医療機器レギュラトリーサイエンス財団,Vol. 50,No. 3,p. 122-134,2019年03月
  • アルファ線放出核種を用いた新規がん核医学治療薬の創製,兼田 加珠子,福田 光宏,金井 好克,畑澤 順,中野 貴志,深瀬 浩一,篠原 厚,張 子見,白神 宜史,渡部 直史,下山 敦史,真鍋 良幸,樺山 一哉,豊嶋 厚史,吉村 崇,日本薬理学会年会要旨集,公益社団法人 日本薬理学会,Vol. 92,No. 0,p. 3-P-109,2019年
  • Analysis of Electrostatic Interaction between Ganglioside GM3 and Transmembrane Peptide,Yuka Nimura,Kazuya Kabayama,Yuya Asahina,Shinya Hanashima,Hironobu Hojo,Michio Murata,Koichi Fukase,IRAGO CONFERENCE 2018: A 360-DEGREE OUTLOOK ON CRITICAL SCIENTIFIC AND TECHNOLOGICAL CHALLENGES FOR A SUSTAINABLE SOCIETY,AMER INST PHYSICS,Vol. 2067,2019年
  • アルファ線核医学治療の薬剤開発に向けた取扱安全基準構築への考察,長谷川 功紀,深瀬 浩一,矢野 恒夫,核医学,(一社)日本核医学会,Vol. 55,No. Suppl.,p. S183-S183,2018年11月
  • アルファ線核医学治療のための薬剤開発の考察(その1),矢野 恒夫,長谷川 功紀,蜂須賀 暁子,深瀬 浩一,平林 容子,医薬品医療機器レギュラトリーサイエンス,(一財)医薬品医療機器レギュラトリーサイエンス財団,Vol. 49,No. 10,p. 676-684,2018年10月
  • がん細胞型アミノ酸トランスポーターを標的とした新規核医学治療薬の開発(Investigation of novel drug for nuclear medicine targeting to cancer specific amino acid transporter, LAT1),兼田 加珠子,張 子見,真鍋 良幸,下山 敦史,樺山 一哉,金井 好克,深瀬 浩一,日本癌学会総会記事,日本癌学会,Vol. 77回,p. 865-865,2018年09月
  • アミノ酸トランスポーターLAT1を標的とするα線がんミサイル療法の開発,兼田 加珠子,張 子見,真鍋 良幸,下山 敦史,樺山 一哉,白神 宜史,金井 好克,畑澤 順,深瀬 浩一,篠原 厚,日本生化学会大会プログラム・講演要旨集,(公社)日本生化学会,Vol. 91回,p. [2P-272],2018年09月
  • 短寿命α線核種を用いた新規抗がん薬開発の検討,兼田 加珠子,張 子見,池田 卓海,神田 晃充,市村 聡一朗,真鍋 良幸,下山 敦史,樺山 一哉,永田 光知郎,渡部 直史,豊嶋 厚史,金井 好克,吉村 崇,福田 光宏,深瀬 浩一,篠原 厚,生命科学系学会合同年次大会,生命科学系学会合同年次大会運営事務局,Vol. 2017年度,p. [2PT26-0899)],2017年12月
  • ガングリオシドGM3とインスリン受容体の膜貫通ペプチドの静電的相互作用解析,二村 友香,樺山 一哉,朝比奈 雄也,花島 慎弥,北條 裕信,村田 道雄,深瀬 浩一,生命科学系学会合同年次大会,生命科学系学会合同年次大会運営事務局,Vol. 2017年度,p. [3P-0030],2017年12月
  • ガングリオシドGM3のアシル鎖構造に基づく新たな自然免疫応答と慢性炎症,狩野 裕考,郷 慎司,新田 昂大,Veilon Lucas,藤居 真優,樺山 一哉,下山 敦史,深瀬 浩一,安藤 弘宗,石田 秀治,名取 良浩,吉村 祐一,鈴木 明身,井ノ口 仁一,脂質生化学研究,日本脂質生化学会,Vol. 59,p. 137-139,2017年06月
  • 極長鎖GM3分子種による慢性炎症惹起メカニズム,狩野 裕考,郷 慎司,新田 昂大,ヴェイロン・ルーカス,カッタニォ・アンナ,レティツァ・マリレナ,名取 良浩,吉村 祐一,安藤 弘崇,石田 秀治,樺山 一哉,下山 敦史,深瀬 浩一,チャンパ・マリア,マウリ・ラウラ,プリネッティ・アレッサンドロ,ソニーノ・サンドロ,鈴木 明身,井ノ口 仁一,日本生化学会大会プログラム・講演要旨集,(公社)日本生化学会,Vol. 89回,p. [2P-067],2016年09月
  • 合成糖鎖の細胞膜提示システムによる糖脂質機能の解明,樺山 一哉,三宅 秀斗,真鍋 良幸,山地 俊之,花田 賢太郎,深瀬 浩一,脂質生化学研究,日本脂質生化学会,Vol. 58,p. 142-143,2016年05月
  • 内因性リガンドとしての極長鎖GM3ガングリオシドによる慢性炎症惹起機構,狩野 裕考,郷 慎司,新田 昂大,Veillon Lucas,Cattaneo Anna,Letizia Marilena,名取 良浩,吉村 祐一,安藤 弘宗,石田 秀治,樺山 一哉,下山 敦史,深瀬 浩一,Ciampa Maria,Mauri Laura,Prinetti Alessandro,Sonnino Sandro,鈴木 明身,井ノ口 仁一,脂質生化学研究,日本脂質生化学会,Vol. 58,p. 144-146,2016年05月
  • 合成糖鎖を用いた細胞膜糖脂質の機能評価,樺山 一哉,三宅 秀斗,Chen Siyu,真鍋 良幸,深瀬 浩一,日本生化学会大会・日本分子生物学会年会合同大会講演要旨集,(公社)日本生化学会,Vol. 88回・38回,p. [1P0299]-[1P0299],2015年12月
  • Functional analyses of a novel type of CA19-9 carrier molecules in micro lipid membrane,Tomomi Minehira,Naofumi Uozumi,Hitomi Asazawa,Atsuko Sawanobori,Shinji Takamatsu,Yoshihiro Kamada,Katsunori Tanaka,Koichi Fukase,Eiji Miyoshi,GLYCOBIOLOGY,OXFORD UNIV PRESS INC,Vol. 24,No. 11,p. 1199-1199,2014年11月,研究発表ペーパー・要旨(国際会議)
  • TLR4/MD-2のリガンド認識と応答性の連関 Lipopolysaccharide binding protein(LBP)とCD14の要求性の相違と炎症性決定の分子基盤,谷村 奈津子,齋藤 伸一郎,大戸 梅治,松本 文,高村 祥子,司,藤本 ゆかり,深瀬 浩一,清水 敏之,三宅 健介,エンドトキシン・自然免疫研究,日本エンドトキシン・自然免疫研究会,Vol. 17,p. 61-66,2014年11月
  • CA19-9の輸送に関わる新規膜複合体構成蛋白質の機能解析(Functional analysis of a protein associated with trafficking of lipid membrane complex with CA19-9 antigen),峰平 朋実,魚住 尚文,浅澤 瞳美,高松 真二,鎌田 佳宏,田中 克典,深瀬 浩一,三善 英知,藤井 宏修,日本癌学会総会記事,日本癌学会,Vol. 72回,p. 351-351,2013年10月
  • 単糖のデンドリマー型クラスターの合成とPETイメージング,LI Haosheng,SIWU Eric R. O,岩田隆幸,野崎聡,長谷川功紀,渡辺恭良,田中克典,深瀬浩一,日本化学会講演予稿集,Vol. 92nd,No. 4,2012年03月09日
  • Microfluidic synthesis of biofunctional molecules: Application to glycan synthesis,Koichi Fukase,ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY,AMER CHEMICAL SOC,Vol. 241,2011年03月,研究発表ペーパー・要旨(国際会議)
  • マイクロ経路内および固相上での効率的グリコシル化反応を基盤としたN-結合型糖タンパク質糖鎖のライブラリー指向型合成,月刊ファインケミカル、シーエムシー出版,2011年
  • Library-Directed Solid-Phase and Microfluidic Synthesis of N-Linked Glycans,2011年
  • ポリリジンデンドリマー型糖鎖クラスターの効率的合成を基盤としたN‐結合型糖鎖の非侵襲的イメージング,田中克典,SIWU Eric R.O,南香莉,長谷川功紀,野崎聡,金山洋介,小山幸一,渡辺恭良,深瀬浩一,日本化学会バイオテクノロジー部会シンポジウム講演要旨集,Vol. 13th,2010年09月24日
  • 高速6π‐アザ電子環状反応による高速アミノ基標識キット,STELLA+の開発,田中克典,横井里美,中山郁理,小山幸一,長谷川功紀,田原強,渡辺恭良,深瀬浩一,日本化学会バイオテクノロジー部会シンポジウム講演要旨集,Vol. 13th,2010年09月24日
  • 5 アザ電子環状反応を基盤とするタンパク質および細胞表層の高速標識化とN-結合型糖鎖の"生きている動物内"でのイメーシング(口頭発表の部),田中 克典,南 香莉,Siwu Eric R. O,増山 達郎,小山 幸一,横井 里美,長谷川 功紀,田原 強,水間 広,野崎 聡,金山 洋介,和田 康弘,尾上 浩隆,渡辺 恭良,深瀬 浩一,天然有機化合物討論会講演要旨集,天然有機化合物討論会実行委員会,Vol. 52,No. 0,p. 25-30,2010年
  • 高反応性アミノ基標識プローブの設計に基づく生体高分子の非侵襲撃的イメージング,化学同人,2010年
  • 糖鎖の侵襲的イメージング,メディカルドウ,2010年
  • Chemical Synthesis of Bacterial Lipid A,Shoichi Kusumoto,Koichi Fukase,Yukari Fujimoto,Microbial Glycobiology,Vol. 2009, 415-427,p. 413-427,2010年
  • 糖鎖を用いた生体内イメージングとターゲティング,シーエムシー出版,2010年
  • 糖鎖関連物質の非侵略的インビボイメージングによる診断法開発への展望,医学書院,2010年
  • 蛍光およびPETによるN‐結合型糖鎖クラスターのインビボイメージング,SIWU Eric R. O,南香莉,長谷川功紀,野崎聡,金山洋介,小山幸一,渡辺恭良,田中克典,深瀬浩一,日本糖質学会年会要旨集,Vol. 29th,2009年08月10日
  • 高速電子環状反応を基盤としたN‐結合型糖タンパク質糖鎖クラスターのPETイメージング,SIWU Eric R. O,南香莉,長谷川功紀,金山洋介,小山幸一,渡辺恭良,田中克典,深瀬浩一,日本化学会講演予稿集,Vol. 89th,No. 2,2009年03月13日
  • Chemistry-based Labeling and Engineering on Proteins and Cell Surfaces: Application to Non-invasive Imaging of Oligosaccharide Derivatives,Chemical Biology (Japanese Society for Chemical Biology),Vol. 2, 7-12.,2009年
  • Synthesis and immunostimulatory activities of lipopeptides from Gram-positive bacteria,Peptide Science,Vol. 2008, 155-156,2009年
  • Synthesis and biofunctional studies of bacterial immunostimulating glycoconjugates.,Transworld Research Network,2009年
  • 第三の生命鎖「糖鎖」を活用•制御するケミカルバイオロジー,シーエムシー出版,2009年
  • 糖鎖のインビボバイオイメージング,シーエム シー出版,2009年
  • Chemical synthesis of bacterial lipid A.,Elsevier,2009年
  • Chemistry-based Labeling and Engineering on Proteins and Cell Surfaces: Application to Non-invasive Imaging of Oligosaccharide Derivatives,Chemical Biology (Japanese Society for Chemical Biology),Vol. 2, 7-12.,2009年
  • Synthesis and immunostimulatory activities of lipopeptides from Gram-positive bacteria,Peptide Science,Vol. 2008, 155-156,2009年
  • Chemical synthesis of bacterial lipid A.,Microbial Glycobiology,Vol. 2009, 415-427,2009年
  • アザ電子環状反応による細胞および微量タンパク質の超高速標識化とPETイメージング,田中克典,南香莉,藤井遥平,深瀬浩一,長谷川功紀,田原強,水間広,和田康弘,渡辺恭良,日本化学会講演予稿集,Vol. 88th,No. 2,2008年03月12日
  • Efficient Synthesis of Oligosaccharides and Synthesis of Pathogen-Associated Molecular Patterns for Their Biofunctional Studies.,Experimental Glycoscience, Glycochemistry,,Vol. 200-205,2008年
  • 超高速アザ電子環状反応を用いた生体分子標識化法の開発とPETイメージングへの応用,田中克典,増山達郎,南香莉,藤井遥平,長谷川功紀,田原強,水間広,和田康弘,渡辺恭良,深瀬浩一,生体機能関連化学シンポジウム講演要旨集,Vol. 22nd,p. 292-293,2007年09月10日
  • アザ電子環状反応を用いた超高速標識化法の開発:糖タンパク質のPETイメージング,田中克典,増山達郎,藤井遥平,南香莉,長谷川功紀,田原強,水間広,和田康弘,渡辺恭良,深瀬浩一,日本糖質学会年会要旨集,Vol. 27th,2007年07月10日
  • 生体高分子の超高速アミノ基標識化に基づくPETイメージングの開発,増山達郎,田中克典,長谷川功紀,田原強,水間広,渡辺恭良,深瀬浩一,日本化学会講演予稿集,Vol. 87th,No. 2,2007年03月12日
  • コンビナトリアル合成法,三共出版,2007年
  • Joint meeting of the society for Leukocyte Niology and the International Endotoxin and Innate Immunity Society, “Innate Immunity:Receptors, Regulation, and Response” November 9-11,2006, San Antonio, Texas,医薬の門社,2007年
  • Synthesis of Lipopolysaccharide, Peptidoglycan, and Lipoteichoic Acid Fragments,S. Kusumoto,K. Fukase,Y. Fujimoto,Comprehensive Glycoscience: From Chemistry to Systems Biology,Elsevier,Vol. 1-4,p. 685-711,2007年01月01日
  • New labeling method of biomolecules via rapid azaelectrocyclization: application to PET imaging,Peptide Science,Vol. 91-94,2007年
  • Synthesis of meso-diaminopimelic acid for construction of gram-negative bacterial peptidoglycan partial structures,Peptide Science,Vol. 121-122,2007年
  • Expression of various Toll-like receptors, NOD1, and NOD2, in human oral epithelial cells, and their function,Interface Oral Health Science,Vol. 225-230,2007年
  • Meso-diaminopimelic acid and meso-lanthionine, amino acids peculiar to bacterial cell-wall peptidoglycans, activate human epithelial cells in culture via NOD1.,Interface Oral Health Science,Vol. 275-276,2007年
  • Polymer-supported and tag-assisted methods in oligosaccharide synthesis,Springer,2007年
  • Combinatorial methods on oligosaccharide synthesis.,Springer,2007年
  • Synthesis of Lipopolysaccharide, Peptidoglycan, and Lipoteichoic Acid Fragments,S. Kusumoto,K. Fukase,Y. Fujimoto,Comprehensive Glycoscience: From Chemistry to Systems Biology,Elsevier,Vol. 1-4,p. 685-711,2007年01月01日
  • Synthesis of lipopolysaccharide, peptidoglycan, and lipoteichoic acid fragments,Elsevier,2007年
  • Synthesis of meso-diaminopimelic acid for construction of gram-negative bacterial peptidoglycan partial structures,Peptide Science,Vol. 121-122,2007年
  • New labeling method of biomolecules via rapid azaelectrocyclization: application to PET imaging,Peptide Science,Vol. 91-94,2007年
  • Meso-diaminopimelic acid and meso-lanthionine, amino acids peculiar to bacterial cell-wall peptidoglycans, activate human epithelial cells in culture via NOD1.,Interface Oral Health Science,Vol. 275-276,2007年
  • Expression of various Toll-like receptors, NOD1, and NOD2, in human oral epithelial cells, and their function,Interface Oral Health Science,Vol. 225-230,2007年
  • Combinatorial methods on oligosaccharide synthesis.,Springer,2007年
  • Polymer-supported and tag-assisted methods in oligosaccharide synthesis,2007年
  • Comprehensive Glycoscience "Synthesis of lipopolysaccharide, peptidoglycan, and lipoteichoic acid fragments",Elsevier,2007年
  • エンドトキシン研究9「受容体機能の制御を指向したリ ピドAの合成と生物活性」,医学図書出版,2006年
  • エンドトキシン研究9「ヒト口腔上皮細胞のTLR系ならびにNOD系分子発現とその機能ー特に抗菌物質産生について」,医学図書出版,2006年
  • Synthesis of fluorescent probe for intracellular innate immune receptor Nod1,Peptide Science,2006年
  • Synthesis of potent immunostimulating Nod1 ligands: acylated diaminopimelic acid containing peptides,Peptide Science,Vol. 156,2006年
  • 糖鎖科学の新展開「固相合成ならびに固相-液相のハイブリッド法による糖鎖の迅速合成」,エヌ・ティー・エス刊行,2005年
  • エンドトキシン研究8-その新たな展開-, 「自然免疫系の細菌認識におけるNOD系とTLR経刺激の相乗作用」,医学図書出版,2005年
  • 未来を拓く糖鎖科学「糖鎖の効率合成法の開発と免疫増強活性複合糖質の合成と機能研究」,金芳堂,2005年
  • Synthesis based on affinity separation: A new methodology for high-throughput synthesis using affinity tags,K Fukase,SQ Zhang,Y Fukase,N Umesako,S Kusumoto,NEW DISCOVERIES IN AGROCHEMICALS,AMER CHEMICAL SOC,Vol. 892,p. 87-98,2005年
  • Synthesis and biological activities of lipid A mimics possessing acidic amino acid,M Akamatsu,M Kataoka,Y Fujimoto,Y Suda,K Fukase,S Kusumoto,GLYCOBIOLOGY,OXFORD UNIV PRESS INC,Vol. 14,No. 11,p. 1201-1202,2004年11月,研究発表ペーパー・要旨(国際会議)
  • Host recognition of peptidoglycan by intracellular receptor Nod1 and Nod2, investigation with synthetic partial structures,A Kawasaki,S Inamura,A Shimoyama,N Inohara,G Nunez,Y Fujimoto,K Fukase,S Kusumoto,GLYCOBIOLOGY,OXFORD UNIV PRESS INC,Vol. 14,No. 11,p. 1199-1200,2004年11月,研究発表ペーパー・要旨(国際会議)
  • Synthesis and biological activity of Helicobacter pylori lipopolysaccharide partial structures containing 2-keto-3-deoxy-D-manno-octonic acid (Kdo),M Iwata,N Imakita,Y Suda,Y Fujimoto,K Fukase,S Kusumoto,GLYCOBIOLOGY,OXFORD UNIV PRESS INC,Vol. 14,No. 11,p. 1201-1201,2004年11月,研究発表ペーパー・要旨(国際会議)
  • Synthesis based on affinity separation using interaction between podand type tag and ammonium ion: Application to oligosaccharide synthesis,M Takashina,Y Hori,S Kusumoto,K Fukase,GLYCOBIOLOGY,OXFORD UNIV PRESS INC,Vol. 14,No. 11,p. 1199-1199,2004年11月,研究発表ペーパー・要旨(国際会議)
  • New method for deprotection of 2,2,2-trichloroethoxycarbonyl (Troc) group by using radical reaction,H Tokimoto,K Fukase,GLYCOBIOLOGY,OXFORD UNIV PRESS INC,Vol. 14,No. 11,p. 1200-1200,2004年11月,研究発表ペーパー・要旨(国際会議)
  • New separation method for (R)- and (S)-form of lipopolysaccharide,T Goi,S Kusumoto,K Fukase,GLYCOBIOLOGY,OXFORD UNIV PRESS INC,Vol. 14,No. 11,p. 1200-1200,2004年11月,研究発表ペーパー・要旨(国際会議)
  • 6 化学フロンティア○14 ロボット・マイクロ合成最前線 化学フロンティア○14 ロボット・マイクロ合成最前線 「固相法と固相―液相ハイブリッド法」,化学同人,2004年
  • Synthesis based on affinity separation: a new methodology for high-throughput synthesis using affinity tags,Am. Chem. Soc.,Vol. 8, 87-98/,,2004年
  • Mechanism of immunostimulating action of peptidoglycan, investigation with synthetic partial structures,Peptide Science,Vol. 2004, 109-112/,,2004年
  • Mechanism of immunostimulating action of peptidoglycan, investigation with synthetic partial structures,Peptide Science,Vol. 2004, 109-112/,,2004年
  • エンドトキシン研究6「脂質部に多様性を有するリピドA類縁体の合成活性の制御と立体の予測」,医学図書出版,2003年
  • Combinatorial synthesis: Solution-phase synthesis and solid-phase split & mix synthesis,K Fukase,JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN,SOC SYNTHETIC ORGANIC CHEM JPN,Vol. 60,No. 5,p. 442-453,2002年05月
  • 固相・液相ハイブリッド法を活用した糖鎖合成,有機合成化学協会誌,Vol. 60,5,494/,,2002年
  • Sugar chain synthesis utilizing solid phase-liquid phase hybrid method.,Yuki Gosei Kagaku Kyokaishi,Vol. 60(5), 494-495/,,2002年
  • コンビナトリアル合成手法:液相合成と固相スプリット&ミックス合成について,有機合成化学協会誌,Vol. 60,5,442/,

著書

  • 糖鎖の新機能開発・応用ハンドブック : 創薬・医療から食品開発まで,津本, 浩平,加藤, 晃一,秋吉, 一成,鷹羽, 武史,深瀬, 浩一,古川, 鋼一,エヌ・ティー・エス,ISBN:9784860434090,2015年
  • クリックケミストリー : 基礎から実用まで,高田, 十志和,小山, 靖人,深瀬, 浩一,シーエムシー出版,ISBN:9784781309545,2014年
  • 自然免疫の鍵を担う細菌複合糖質リポ多糖ならびにペプチドグリカンの合成と機能研究,深瀬, 浩一,[深瀬浩一],2008年
  • 固相法と固相-液相ハイブリッド法による糖鎖の迅速合成とライブラリー合成,深瀬, 浩一,[深瀬浩一],2005年
  • Utilization of phase tag in liquid phase rapid synthesis.,Sentan Kagaku Shirizu,2003年
  • 固相法による糖鎖の自動合成法の開発,深瀬, 浩一,[深瀬浩一],2002年
  • Affinity分離を利用した新しい合成手法,深瀬, 浩一,[深瀬浩一],2002年
  • Combinatorial chemistry: approach from organic chemistry.,Kagaku Furontia (2002), 5(Seimei Kagaku no Nyu Sentoraru Doguma),2002年
  • Combinatorial and Solid-Phase Methods in Oligosacchalide Synthesis,Springer,2001年
  • コンビナトリアル化学の新展開 : 分子機能の解明と触媒開発への適用,深瀬, 浩一,深瀬浩一,2000年
  • 固相法による糖鎖の迅速合成,深瀬, 浩一,大阪大学大学院理学研究科,1997年

特許・実用新案・意匠

  • 新規化合物及びその利用,田中 克典,渡辺 恭良,野崎 聡,深瀬 浩一,特許第6327547号,特願2013-161407,出願日:2013年08月02日,登録日:2018年04月27日
  • 水不溶性担体及びエンドトキシン吸着材,深瀬 浩一,田中 克典,畑中 美博,築地 美鈴,斉藤 政利,特許第5682916号,特願2011-003976,出願日:2011年01月12日,登録日:2015年01月23日
  • 機能性分子用担体,深瀬 浩一,田中 克典,渡辺 恭良,小山 幸一,特許第5449820号,特願2009-080637,出願日:2009年03月27日,登録日:2014年01月10日
  • 新規ヘキサトリエン-β-カルボニル化合物,深瀬 浩一,田中 克典,渡辺 恭良,田原 強,長谷川 功紀,特許第5013378号,特願2008-557126,出願日:2008年02月05日,登録日:2012年06月15日
  • 細菌内毒素吸着剤及びそのスクリーニング方法,深瀬 浩一,ハンス ペーター ネスラー,特許第3893030号,特願2001-119547,出願日:2001年04月18日,登録日:2006年12月15日
  • アジドハロゲノベンジル誘導体及び水酸基の保護方法,楠本 正一,深瀬 浩一,特許第3837876号,特願平9-300998,出願日:1997年10月31日,登録日:2006年08月11日
  • 糖の蛍光標識方法および人工複合糖質の製造法,楠本 正一,深瀬 浩一,特許第3821494号,特願平6-041545,出願日:1994年03月11日,登録日:2006年06月30日
  • 2-アミノピリジン誘導体、その製造方法及び蛍光標識剤,楠本 正一,長谷 純宏,深瀬 浩一,特許第3122520号,特願平4-088314,出願日:1992年03月13日,登録日:2000年10月20日
  • アルキニルメチル基で保護したカルボキシル基および水酸基の脱保護方法,楠本 正一,深瀬 浩一,特許第3069692号,特願平10-364341,出願日:1998年12月22日,登録日:2000年05月26日
  • アルキニルメチルオキシカルボニル基で保護したアミノ基および水酸基の脱保護方法,楠本 正一,深瀬 浩一,特許第3054704号,特願平10-364340,出願日:1998年12月22日,登録日:2000年04月14日
  • 211At標識化アミノ酸誘導体を含む医薬組成物及びその製造方法,深瀬 浩一,篠原 厚,金井 好克,樺山 一哉,兼田 加珠子,張 子見,畑澤 順,白神 宜史,下山 敦史,真鍋 良幸,WO2019-176505,JP2019006800,出願日:2019年02月22日
  • リピドA,國澤 純,深瀬 浩一,清野 宏,WO2018-155051,JP2018002120,出願日:2018年01月24日
  • 糖鎖結合ワクチン抗原及び糖鎖導入剤,三善 英知,深瀬 浩一,真鍋 良幸,高松 真二,種村 匡弘,WO2016-104647,JP2015086104,出願日:2015年12月24日
  • 電気化学的手法を用いたハロゲン化物の製造方法,中村 浩之,佐藤 伸一,深瀬 浩一,特願2018-239130,出願日:2018年12月21日
  • アルファ線核医学治療剤の安全性評価方法およびスクリーニング方法,矢野 恒夫,深瀬 浩一,福田 光宏,特願2019-041946,出願日:2019年03月07日
  • ホウ素クラスター脂質への放射線同位元素標識化法と標識化ホウ素クラスター脂質のウイルス粒子への導入法,深瀬 浩一,金田 安史,下山 敦史,真鍋 良幸,中村 浩之,佐藤 伸一,特願2018-048565,出願日:2018年03月15日
  • トール様受容体4活性化作用を有するフニクロシン誘導体及びその用途,藤本 ゆかり,深瀬 浩一,高津 聖志,長井 良憲,岡本 直樹,特願2014-201593,出願日:2014年09月30日
  • プリスタンの化学合成法
  • リジンデンドリマー型糖鎖クラスターの製造法とその応用
  • 超音波探触子とその製造方法及び音響レンズとその製造方法
  • 人工複合糖質
  • Modulators of Nod1 Signaling (アメリカ)
  • 人工複合糖質
  • 細菌内毒素吸着剤及びそのスクリーニング方法
  • 糖加水分解酵素の酵素活性測定法
  • アルキニルメチルオキシカルボニル基で保護したアミノ酸および水酸基の保護方法
  • アジドハロゲノベンジル誘導体、糖化合物及び水酸基の保護方法
  • Modulators of Nod1 Signaling (America)
  • Method of producing a fluorescence-labeled carbohydrate or protein conjugate utilizing a bifunctional 2-aminopyridine.
  • Preparation of azidohalobenzyl halide derivatives and method for protecting sugar compounds and hydroxy groups in liquid and solid phase synthesis.
  • Protection of carboxyl and hydroxy groups by alkynylmethyl group, and deprotection of the protected groups.
  • Protection of amino and hydroxy groups by (alkynylmethyl)oxycarbonyl group, and deprotection of the protected groups.
  • Method for determining enzyme activity of sugar hydrolases.
  • Bacterial endotoxin adsorbent and its screening method.

作品

  • 硫酸化糖脂質の配座解析研究,1998年 ~ 2000年
  • Conformational studies on a unique bis-sulfated glycolipid using NMR spectroscopy and molecular dynamics simulations,1998年 ~ 2000年
  • コンビナトリアル化学の新展開:分子機能の解明と触媒開発への適用,1997年 ~ 1998年
  • Novel Application of Combinatorial Chemistry,1997年 ~ 1998年
  • マイクロフロー合成と固相合成を基盤にした糖鎖ならびに関連化合物の高度集積合成,2011年 ~
  • 糖鎖合成と生体イメージングを基盤とする糖鎖の生物機能解析,2011年 ~
  • 細胞内ペプチドグリカン受容体NOD1, NOD2の新規リカンド創生と機能の制御,2011年 ~
  • マイクロフロー合成と固相合成を基盤にした糖鎖ならびに関連化合物の高度集積合成,2010年 ~
  • 生細胞選択的な標識化、生細胞イメージングならびに細胞機能制御,2010年 ~
  • 糖鎖の化学合成と免疫系、神経系における機能研究,2010年 ~
  • 核酸・ぺプチド・糖のケミカルバイオロジーを基盤とした創薬分子イメージング(糖鎖クラスタープローブの開発と標識化),2009年 ~
  • 糖鎖の化学合成と免疫系、神経系における機能研究,2009年 ~
  • 糖質化合物の合成,2009年 ~
  • 生細胞選択的な標識化、生細胞イメージングならびに細胞機能制御,2009年 ~
  • マイクロフロー合成と固相合成を基盤にした糖鎖ならびに関連化合物の高度集積合成,2009年 ~
  • 糖鎖の化学合成と免疫系、神経系における機能研究,2008年 ~
  • 糖質化合物の合成,2008年 ~
  • 核酸・ぺプチド・糖のケミカルバイオロジーを基盤とした創薬分子イメージング(糖鎖クラスタープローブの開発と標識化),2008年 ~
  • 自然免疫の鍵を担う細胞複合糖質の合成と生物機能解明研究,2008年 ~
  • 超高速電子環状反応を用いた生体分子の標識化と陽電子断層撮影への応用,2008年 ~
  • 生物製剤と糖鎖のPETイメージングを利用した新規医療診断システムと創薬への展開,2008年 ~
  • 糖質化合物の合成,2007年 ~
  • 核酸・ぺプチド・糖のケミカルバイオロジーを基盤とした創薬分子イメージング,2007年 ~
  • 生物製剤と糖鎖のPETイメージングを利用した新規医療診断システムと創薬への展開,2007年 ~
  • 細菌由来複合糖質の合成に関する研究,2007年 ~
  • 超高速電子環状反応を用いた生体分子の標識化と陽電子断層撮影への応用,2007年 ~
  • 受容体機能の制御を目指した免疫増強複合糖質リポ多糖ならびに類縁体の合成研究,2007年 ~
  • 自然免疫の鍵を担う細菌複合糖質リポ多糖ならびにペプチドグリカンの合成と機能研究,2007年 ~
  • 糖鎖の効率的合成法の開発と糖鎖ライブラリーの構築,2006年 ~
  • 受容体機能の制御を目指した免疫増強複合糖質リポ多糖ならびに類縁体の合成研究,2006年 ~
  • 細菌由来の免疫増強活性複合糖質の構造と機能に関する化学的研究,2006年 ~
  • 自然免疫の鍵を担う細菌複合糖質リポ多糖ならびにペプチドグリカンの合成と機能研究,2006年 ~
  • 腸内細菌や発酵菌由来免疫活性化因子の精製ならびに構造解析研究,2006年 ~
  • リピドAならびに類縁体、標識体の合成,2006年 ~
  • 生物活性有機化合物(プリスタン)化学合成の研究,2006年 ~
  • 自然免疫の鍵を担う細菌複合糖質の合成と生物機能解明研究,2006年 ~
  • リピドAならびに類縁体、標識体の合成,2006年 ~
  • 受容体機能の制御を目指した免疫増強複合糖質リポ多糖ならびに類縁体の合成研究,2006年 ~
  • 自然免疫の鍵を担う細菌複合糖質リポ多糖ならびにペプチドグリカンの合成と機能研究,2006年 ~
  • 細胞内ペプチドグリカン受容体NOD1,NOD2の新規リガンド創生と機能の制御,2005年 ~
  • 受容体機能の制御を目指した免疫増強複合糖質リポ多糖の合成研究,2005年 ~
  • 自然免疫の鍵を担う細菌複合糖質リポ多糖ならびにペプチドグリカンの合成と機能研究,2005年 ~
  • 生物新機能と創薬をめざす生体内分子科学,2005年 ~
  • リピドAならびに類縁体、標識体の合成,2005年 ~
  • リピドAならびに類縁体、標識体の合成,2004年 ~
  • 細胞内ペプチドグリカン受容体NOD1,NOD2の新規リガンド創生と機能の制御,2004年 ~
  • 細胞内ペプチドグリカン受容体NOD1,NOD2の新規リガンド創生と機能の制御,2004年 ~
  • リピドAならびに類縁体、標識体の合成,2004年 ~
  • 細胞内ペプチドグリカン受容体NOD1,NOD2の新規リガンド創生と機能の制御,2004年 ~
  • 固相法と固相-液相ハイブリッド法による糖鎖の迅速合成とライブラリー合成,2004年 ~
  • 学術創成研究費「生物新機能と創薬をめざす生体内分子科学」,2004年 ~
  • 吸着型分離操作を行うマイクロ分離機の開発,2004年 ~
  • 細菌表層免疫増強活性複合糖質の機能研究,1988年 ~
  • Functional study of immunostimulating glycoconjugates of bacterial cell surface,1988年 ~

受賞

  • 平成22年度第28回日本化学会学術賞,2011年
  • The CSJ Award for Creative Work,2011年
  • フロー・マイクロ合成研究会 第4回 銅金賞受賞,2009年
  • BCSJ賞,2008年
  • BCSJ Award,2008年
  • BCSJ賞,2004年
  • Bulletin of the Chemical Society of Japan Award,2004年
  • the 2001 Synthesis-Synlett Journal Award,2000年
  • the 2001 Synthesis-Synlett Journal Award,2000年
  • 山形達也賞,1999年
  • 日本化学会進歩賞,1994年
  • 日本化学会進歩賞,1994年

講演・口頭発表等

  • Nod1 Ligands Induce Site-Specific Vascular Inflammation,Hisanori Nishio,Shunsuke Kanno,Sagano Onoyama,Kazuyuki Ikeda,Tamami Tanaka,Koichi Kusuhara,Yukari Fujimoto,Koichi Fukase,Katsuo Sueishi,Toshiro Hara,ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY,2011年05月
  • Failure of mycoplasma lipoprotein MALP-2 to induce NK cell activation through dendritic cell TLR2,Ryoko Sawahata,Hiroaki Shime,Sayuri Yamazaki,Norimitsu Inoue,Takashi Akazawa,Yukari Fujimoto,Koichi Fukase,Misako Matsumoto,Tsukasa Seya,MICROBES AND INFECTION,2011年04月
  • Structures, synthesis, and human Nod1 stimulation of immunostimulatory bacterial peptidoglycan fragments in the environment.,Yukari Fujimoto,Koichi Fukase,Journal of natural products,2011年03月25日
  • Ligand-dependent Toll-like receptor 4 (TLR4)-oligomerization is directly linked with TLR4-signaling,S Saitoh,S Akashi,T Yamada,N Tanimura,F Matsumoto,K Fukase,S Kusumoto,A Kosugi,K Miyake,JOURNAL OF ENDOTOXIN RESEARCH,2004年
  • Human peptidoglycan recognition protein-L is an N-acetylmuramoyl-L-alanine amidase.,Zheng-Ming Wang,Xinna Li,Ross R Cocklin,Minhui Wang,Mu Wang,Koichi Fukase,Seiichi Inamura,Shoichi Kusumoto,Dipika Gupta,Roman Dziarski,The Journal of biological chemistry,2003年12月05日
  • A dominant role of Toll-like receptor 4 in the signaling of apoptosis in bacteria-faced macrophages.,Rudolf Haase,Carsten J Kirschning,Andreas Sing,Percy Schröttner,Koichi Fukase,Shoichi Kusumoto,Hermann Wagner,Jürgen Heesemann,Klaus Ruckdeschel,Journal of immunology (Baltimore, Md. : 1950),2003年10月15日
  • Lipopolysaccharide interaction with cell surface Toll-like receptor 4-MD-2: higher affinity than that with MD-2 or CD14.,Sachiko Akashi,Shin-ichiroh Saitoh,Yasutaka Wakabayashi,Takane Kikuchi,Noriaki Takamura,Yoshinori Nagai,Yutaka Kusumoto,Koichi Fukase,Shoichi Kusumoto,Yoshiyuki Adachi,Atsushi Kosugi,Kensuke Miyake,The Journal of experimental medicine,2003年10月06日
  • Cell activation by monosaccharide lipid A analogues utilizing Toll-like receptor 4.,Riyoko Tamai,Yasuyuki Asai,Masahito Hashimoto,Koichi Fukase,Shoichi Kusumoto,Hideharu Ishida,Makoto Kiso,Tomohiko Ogawa,Immunology,2003年09月
  • Solid-phase synthesis of a phytoalexin elicitor pentasaccharide using a 4-azido-3-chlorobenzyl group as the key for temporary protection and catch-and-release purification,K Egusa,S Kusumoto,K Fukase,EUROPEAN JOURNAL OF ORGANIC CHEMISTRY,2003年08月
  • An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid.,Mathias Chamaillard,Masahito Hashimoto,Yasuo Horie,Junya Masumoto,Su Qiu,Lisa Saab,Yasunori Ogura,Akiko Kawasaki,Koichi Fukase,Shoichi Kusumoto,Miguel A Valvano,Simon J Foster,Tak W Mak,Gabriel Nuñez,Naohiro Inohara,Nature immunology,2003年07月
  • Endotoxic and immunobiological activities of a chemically synthesized lipid A of Helicobacter pylori strain 206-1.,Tomohiko Ogawa,Yasuyuki Asai,Yasuhiro Sakai,Masato Oikawa,Koichi Fukase,Yasuo Suda,Shoichi Kusumoto,Toshihide Tamura,FEMS immunology and medical microbiology,2003年05月15日
  • Synthesis and biological activities of lipid A analogs possessing beta-glycosidic linkage at 1-position,K Fukase,A Ueno,Y Fukase,M Oikawa,Y Suda,S Kusumoto,BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN,2003年03月
  • Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease.,Naohiro Inohara,Yasunori Ogura,Ana Fontalba,Olga Gutierrez,Fernando Pons,Javier Crespo,Koichi Fukase,Seiichi Inamura,Shoichi Kusumoto,Masahito Hashimoto,Simon J Foster,Anthony P Moran,Jose L Fernandez-Luna,Gabriel Nuñez,The Journal of biological chemistry,2003年02月21日
  • Chemical synthesis of cyclodextrins by using intramolecular glycosylation.,Masahiro Wakao,Koichi Fukase,Shoichi Kusumoto,The Journal of organic chemistry,2002年11月15日

委員歴

  • 学協会,Combinatorial Chemistry研究会,代表幹事,幹事,1996年 ~ 1997年
  • 学協会,日本化学会,欧文誌編集委員,2009年 ~
  • 学協会,日本糖質学会,理事,2007年 ~
  • 学協会,日本ペプチド学会,評議員,2006年 ~
  • 学協会,天然有機化合物討論会,世話人,2006年 ~
  • 学協会,International Endotoxin and Innate Immunity Society,Program Committee,2006年 ~
  • 学協会,日本ケミカルバイオロジー研究会,世話人,2006年 ~
  • 学協会,日本ペプチド学会,評議員,2006年 ~
  • 学協会,日本糖質学会,評議員,2005年 ~
  • 学協会,日本化学会・生体機能関連化学部会,役員,2005年 ~
  • 学協会,日本糖質学会,評議員,2005年 ~
  • 学協会,天然物化学談話会,世話人代表,2004年 ~
  • 学協会,日本ペプチド学会,評議員,2000年 ~
  • 学協会,Combinatorial Chemistry研究会,幹事,1995年 ~
  • 学協会,Combinatorial Chemistry研究会,幹事,1995年 ~