オラパリブ+ベバシズマブ併用療法で2年の完全寛解を得た後に手術を実施した漿液性卵巣癌の1例

石井 裕友, 中川 慧, 角田 守, 戸田 有朱香, 木瀬 康人, 瀧内 剛, 小玉 美智子, 橋本 香映, 上田 豊, 澤田 健二郎, 木村 正

日本婦人科腫瘍学会学術講演会プログラム・抄録集　Vol. 66回　p. 284-284　2024/07

子宮肉腫の下大静脈内再発に対して,下大静脈切除および人工血管置換術を行った1例

石井 裕友, 中川 慧, 角田 守, 戸田 有朱香, 木瀬 康人, 瀧内 剛, 小玉 美智子, 橋本 香映, 上田 豊, 澤田 健二郎, 木村 正, 島村 和男

産婦人科の進歩　Vol. 76　No. 2　p. 173-173　2024/05

右総腸骨静脈内進展を伴うCotyledonoid dissecting leiomyomaの1例

大槻 摩弥, 木瀬 康人, 角田 守, 戸田 有朱香, 中川 慧, 瀧内 剛, 小玉 美智子, 橋本 香映, 上田 豊, 澤田 健二郎, 太田 崇詞, 木村 正

産婦人科の進歩　Vol. 76　No. 2　p. 182-182　2024/05

術前に卵巣癌を疑われた悪性リンパ腫の1例

安井 友紀, 橋本 香映, 角田 守, 中川 慧, 戸田 有朱香, 木瀬 康人, 瀧内 剛, 小玉 美智子, 上田 豊, 澤田 健二郎, 木村 正

産婦人科の進歩　Vol. 76　No. 2　p. 185-185　2024/05

子宮肉腫の下大静脈内再発に対して,下大静脈切除および人工血管置換術を行った1例

石井 裕友, 中川 慧, 角田 守, 戸田 有朱香, 木瀬 康人, 瀧内 剛, 小玉 美智子, 橋本 香映, 上田 豊, 澤田 健二郎, 木村 正, 島村 和男

産婦人科の進歩　Vol. 76　No. 2　p. 173-173　2024/05

右総腸骨静脈内進展を伴うCotyledonoid dissecting leiomyomaの1例

大槻 摩弥, 木瀬 康人, 角田 守, 戸田 有朱香, 中川 慧, 瀧内 剛, 小玉 美智子, 橋本 香映, 上田 豊, 澤田 健二郎, 太田 崇詞, 木村 正

産婦人科の進歩　Vol. 76　No. 2　p. 182-182　2024/05

術前に卵巣癌を疑われた悪性リンパ腫の1例

安井 友紀, 橋本 香映, 角田 守, 中川 慧, 戸田 有朱香, 木瀬 康人, 瀧内 剛, 小玉 美智子, 上田 豊, 澤田 健二郎, 木村 正

産婦人科の進歩　Vol. 76　No. 2　p. 185-185　2024/05

下平・谷口式子宮頸管円錐切除術後の早産発生率 単一施設における後方視的コホート研究(The incidence of preterm birth after cervical conization by Shimodaira-Taniguchi instrument; a single center retrospective cohort study)

Tabuse Mari, Kawanishi Yoko, Okada Aiko, Nakamura Koji, Miyake Tatsuya, Hiramatsu Kosuke, Mimura Kazuya, Kimura Toshihiro, Ueda Yutaka, Sawada Kenjiro, Endo Masayuki, Kimura Tadashi

日本産科婦人科学会雑誌　Vol. 76　No. 臨増　p. S-344　2024/02

当院での進行・再発子宮頸癌に対するペムブロリズマブ併用療法の検討

赤田 将, 小玉 美智子, 角田 守, 戸田 有朱香, 中川 慧, 木瀬 康人, 瀧内 剛, 橋本 香映, 上田 豊, 澤田 健二郎, 木村 正

産婦人科の進歩　Vol. 75　No. 4　p. 565-565　2023/10

抗腫瘍薬併用下静脈血栓症合併婦人科癌患者に対するエドキサバンの安全性に関する検討

折出 唯志, 澤田 健二郎, 清水 亜麻, 木瀬 康人, 瀧内 剛, 橋本 香映, 小玉 美智子, 小林 栄仁, 中谷 英仁, 木村 正

日本癌治療学会学術集会抄録集　Vol. 61回　p. YOA O66-6　2023/10

Clinical trial assessing the safety of edoxaban with concomitant chemotherapy in patients with gynecological cancer-associated thrombosis (EGCAT study).

Tadashi Oride, Kenjiro Sawada, Aasa Shimizu, Yasuto Kinose, Tsuyoshi Takiuchi, Michiko Kodama, Kae Hashimoto, Eiji Kobayashi, Eiji Nakatani, Tadashi Kimura

Thrombosis journal　Vol. 21　No. 1　p. 57-57　2023/05/15　Research paper (scientific journal)

進行卵巣癌におけるNAC+IDS後の予後予測因子

倉橋 寛樹, 増田 達郎, 戸田 有朱香, 中川 慧, 木瀬 康人, 瀧内 剛, 三好 愛, 小玉 美智子, 小林 栄仁, 橋本 香映, 上田 豊, 澤田 健二郎, 木村 正

産婦人科の進歩　Vol. 75　No. 2　p. 179-179　2023/05　Research paper (other academic)

円錐切除に伴う腟壁・膀胱損傷に対し,大網充填が有効であった1例

山本 岳, 木瀬 康人, 中川 慧, 戸田 明日香, 瀧内 剛, 三好 愛, 小玉 美智子, 小林 栄仁, 橋本 香映, 上田 豊, 澤田 健二郎, 木村 正

産婦人科の進歩　Vol. 75　No. 2　p. 197-197　2023/05　Research paper (other academic)

A single institution's experience with minimally invasive surgery for ovarian cancer, and a systematic meta-analysis of the literature.

Yuji Kamei, Eiji Kobayashi, Eiji Nakatani, Mayu Shiomi, Masaaki Sawada, Mamoru Kakuda, Aska Toda, Satoshi Nakagawa, Kosuke Hiramatsu, Yasuto Kinose, Tsuyoshi Takiuchi, Ai Miyoshi, Michiko Kodama, Kae Hashimoto, Toshihiro Kimura, Yutaka Ueda, Kenjiro Sawada, Tadashi Kimura

International journal of clinical oncology　Vol. 28　No. 6　p. 794-803　2023/04/28　Research paper (scientific journal)

Gastric-Type Adenocarcinoma of the Uterine Cervix Associated with Poor Response to Definitive Radiotherapy.

Airi Kuruma, Michiko Kodama, Yumiko Hori, Kazuaki Sato, Makoto Fujii, Fumiaki Isohashi, Ai Miyoshi, Seiji Mabuchi, Akira Setoguchi, Hiroko Shimura, Takeshi Goto, Aska Toda, Satoshi Nakagawa, Yasuto Kinose, Tsuyoshi Takiuchi, Eiji Kobayashi, Kae Hashimoto, Yutaka Ueda, Kenjiro Sawada, Eiichi Morii, Tadashi Kimura

Cancers　Vol. 15　No. 1　2022/12/28　Research paper (scientific journal)

子宮悪性腫瘍に対する低侵襲手術:ロボットvs腹腔鏡 腹腔鏡からロボット手術への移行期における1医師の現状

小林 栄仁, 角田 守, 中川 慧, 平松 宏祐, 三好 愛, 木瀬 康人, 瀧内 剛, 小玉 美智子, 橋本 香映, 木村 敏啓, 上田 豊, 澤田 健二郎, 木村 正

日本内視鏡外科学会雑誌　Vol. 27　No. 7　p. 1308-1308　2022/12　Research paper (other academic)

Laparoscopic spacer placement for bulky lymph node metastasis of cervical cancer: A case report.

Airi Kuruma, Michiko Kodama, Ai Miyoshi, Fumiaki Isohashi, Aska Toda, Satoshi Nakagawa, Yasuto Kinose, Tsuyoshi Takiuchi, Eiji Kobayashi, Kae Hashimoto, Yutaka Ueda, Kenjiro Sawada, Tadashi Kimura

Gynecologic oncology reports　Vol. 43　p. 101072-101072　2022/10　Research paper (scientific journal)

【プロゲステロン・プロゲストーゲン・プロゲスチン-黄体ホルモンのすべて-】黄体ホルモンの臨床 黄体ホルモンと子宮内膜がん

澤田 健二郎

産科と婦人科　Vol. 89　No. 9　p. 975-981　2022/09　Research paper (scientific journal)

Identification of Malignant Cell Populations Associated with Poor Prognosis in High-Grade Serous Ovarian Cancer Using Single-Cell RNA Sequencing.

Naoki Sumitani, Kyoso Ishida, Kenjiro Sawada, Tadashi Kimura, Yasufumi Kaneda, Keisuke Nimura

Cancers　Vol. 14　No. 15　2022/07/22　Research paper (scientific journal)

当科で経験した子宮頸部小細胞神経内分泌癌11例の後方視的検討

小林 まりや, 中川 慧, 北野 佐季, 木瀬 康人, 瀧内 剛, 三好 愛, 小玉 美智子, 橋本 香映, 小林 栄仁, 上田 豊, 澤田 健二郎, 冨松 拓治, 木村 正

日本婦人科腫瘍学会学術講演会プログラム・抄録集　Vol. 64回　p. 223-223　2022/07　Research paper (other academic)

子宮頸部腺癌に対する根治放射線療法の効果に関する因子の検討

來間 愛里, 小玉 美智子, 中川 慧, 木瀬 康人, 瀧内 剛, 三好 愛, 小林 栄仁, 橋本 香映, 上田 豊, 澤田 健二郎, 冨松 拓治, 木村 正

日本婦人科腫瘍学会学術講演会プログラム・抄録集　Vol. 64回　p. 191-191　2022/07　Research paper (other academic)

当科で経験した子宮頸部小細胞神経内分泌癌11例の後方視的検討

小林 まりや, 中川 慧, 北野 佐季, 木瀬 康人, 瀧内 剛, 三好 愛, 小玉 美智子, 橋本 香映, 小林 栄仁, 上田 豊, 澤田 健二郎, 冨松 拓治, 木村 正

日本婦人科腫瘍学会学術講演会プログラム・抄録集　Vol. 64回　p. 223-223　2022/07

Safety and efficacy of Ninjin'yoeito along with iron supplementation therapy for preoperative anemia, fatigue, and anxiety in patients with gynecological disease: an open-label, single-center, randomized phase-II trial.

Taro Yagi, Kenjiro Sawada, Mayuko Miyamoto, Yasuto Kinose, Satoshi Nakagawa, Tsuyoshi Takiuchi, Michiko Kodama, Eiji Kobayashi, Kae Hashimoto, Seiji Mabuchi, Takuji Tomimatsu, Kiyoshi Yoshino, Tadashi Kimura

BMC women's health　Vol. 22　No. 1　p. 229-229　2022/06/14　Research paper (scientific journal)

Endometrial galectin-3 causes endometriosis by supporting eutopic endometrial cell survival and engraftment in the peritoneal cavity.

Saya Yamashita, Kae Hashimoto, Ikuko Sawada, Minori Ogawa, Erika Nakatsuka, Mahiru Kawano, Yasuto Kinose, Michiko Kodama, Kenjiro Sawada, Tadashi Kimura

American journal of reproductive immunology (New York, N.Y. : 1989)　Vol. 87　No. 6　2022/06　Research paper (scientific journal)

ITP合併卵巣癌の化学療法に伴う血小板低下に対してTPO受容体作動薬を使用した1例

舟津 えり子, 木瀬 康人, 中川 慧, 瀧内 剛, 三好 愛, 小玉 美智子, 橋本 香映, 上田 豊, 澤田 健二郎, 木村 正

産婦人科の進歩　Vol. 74　No. 2　p. 289-289　2022/05　Research paper (scientific journal)

【やせ・肥満と女性のヘルスケア】やせ・肥満と産科婦人科疾患 やせ・肥満と婦人科腫瘍・周術期管理

澤田 健二郎

産科と婦人科　Vol. 89　No. 5　p. 509-514　2022/05　Research paper (scientific journal)

女性医学における骨粗鬆症診療

澤田 健二郎

日本女性医学学会雑誌　Vol. 29　No. 3　p. 480-484　2022/04　Research paper (other academic)

Postoperative lymphocyst formation after pelvic lymphadenectomy for gynecologic cancers: comparison between laparoscopy and laparotomy

Reisa Kakubari, Eiji Kobayashi, Mamoru Kakuda, Tadashi Iwamiya, Tsuyoshi Takiuchi, Michiko Kodama, Kae Hashimoto, Yutaka Ueda, Kenjiro Sawada, Takuji Tomimatsu, Tadashi Kimura

International Journal of Clinical Oncology　Vol. 27　No. 3　p. 602-608　2022/03　Research paper (scientific journal)

【女性医学からみた脂質代謝異常】脂質異常症の管理

澤田 健二郎

HORMONE FRONTIER IN GYNECOLOGY　Vol. 28　No. 4　p. 299-305　2021/12

Sleeping Beauty Transposon Mutagenesis Identifies Genes Driving the Initiation and Metastasis of Uterine Leiomyosarcoma.

Michiko Kodama, Hiroko Shimura, Jean C Tien, Justin Y Newberg, Takahiro Kodama, Zhubo Wei, Roberto Rangel, Kosuke Yoshihara, Airi Kuruma, Aya Nakae, Kae Hashimoto, Kenjiro Sawada, Tadashi Kimura, Nancy A Jenkins, Neal G Copeland

Cancer research　Vol. 81　No. 21　p. 5413-5424　2021/11/01　Research paper (scientific journal)

ウォーレスリングペッサリーにより腟壁全層欠損及び膀胱筋層露出に至った症例

來間 愛里, 小玉 美智子, 文 美智子, 八木 太郎, 戸田 有朱香, 橋本 香映, 澤田 健二郎, 木村 正

日本女性医学学会雑誌　Vol. 29　No. 1　p. 124-124　2021/10

閉経後骨粗鬆症患者に対するゾレドロン酸製剤の治療効果と副作用の検討

小川 美祈, 澤田 健二郎, 大井 友香子, 文 美智子, 來間 愛里, 八木 太郎, 山本 実咲, 戸田 有朱香, 中村 幸司, 木瀬 康人, 小玉 美智子, 橋本 香映, 倉智 博久, 木村 正

日本女性医学学会雑誌　Vol. 29　No. 1　p. 126-126　2021/10

既存の骨粗鬆症治療薬にて効果不十分な閉経後骨粗鬆症女性に対するロモソズマブの有効性の検討

山本 実咲, 澤田 健二郎, 大井 友香子, 來間 愛里, 文 美智子, 八木 太郎, 小川 美祈, 戸田 有朱香, 中村 幸司, 木瀬 康人, 小玉 美智子, 橋本 香映, 倉智 博久, 木村 正

日本女性医学学会雑誌　Vol. 29　No. 1　p. 126-126　2021/10

Turner症候群女性における骨密度

粕谷 香南子, 橋本 香映, 大井 友香子, 文 美智子, 來間 愛里, 八木 太郎, 小川 美祈, 山本 実咲, 戸田 有朱香, 中村 幸司, 木瀬 康人, 小玉 美智子, 澤田 健二郎, 木村 正

日本女性医学学会雑誌　Vol. 29　No. 1　p. 133-133　2021/10

女性医学における骨粗鬆症診療

澤田 健二郎

日本女性医学学会雑誌　Vol. 29　No. 1　p. 81-81　2021/10

漢方臨床レポート 婦人科疾患術前の貧血治療における人参養栄湯の有用性の検討

八木 太郎, 澤田 健二郎

Phil漢方　No. 85　p. 16-19　2021/10

Correlation Between the Transient Elevation of Peripheral Eosinophil Count During Radiotherapy and Acute Diarrhea

TAKAKO KOBAYASHI, FUMIAKI ISOHASHI, DAISUKE EINO, KAZUNORI TANAKA, KENJIRO SAWADA, YUTAKA UEDA, EIJI KOBAYASHI, TAKUJI TOMIMATSU, TADASHI KIMURA, KAZUHIKO OGAWA

Cancer Diagnosis & Prognosis　Vol. 1　No. 4　p. 331-337　2021/09/03　Research paper (scientific journal)

婦人科希少癌である中腎管癌の患者由来腫瘍異種移植(PDX)モデルマウスの樹立と個別化医療の探索

粕谷 香南子, 木瀬 康人, 小玉 美智子, 橋本 香映, 澤田 健二郎, 木村 正

日本癌学会総会記事　Vol. 80回　p. [P2-2]　2021/09

ベバシズマブ投与は卵巣癌におけるmiR-143-3p発現低下に伴うPAI-1高発現を誘導し血管新生を補完する

八木 太郎, 澤田 健二郎, 宮本 真由子, 清水 亜麻, 山本 実咲, 中村 幸司, 木瀬 康人, 木村 正

日本癌学会総会記事　Vol. 80回　p. [E14-5]　2021/09

Magnetic resonance imaging evaluation of pelvic floor structure during pregnancy.

Taro Yagi, Michiko Kodama, Michiko Bun, Hiroko Shimura, Kenjiro Sawada, Masayuki Endo, Tadashi Kimura

European journal of obstetrics, gynecology, and reproductive biology　Vol. 264　p. 289-293　2021/07/28　Research paper (scientific journal)

PARPとATRの併用阻害による卵巣癌in vitroおよびPDX同所移植モデルにおけるPARP阻害剤およびプラチナ製剤耐性の克服(Combination PARP and ATR Inhibition Overcomes PARP Inhibitor and Platinum Resistance in Ovarian Cancer in Vitro and Orthotopic PDX Models)

木瀬 康人, 中村 幸司, 澤田 健二郎, 木村 正, キムヤン, シンプキンスフィオーナ

日本婦人科腫瘍学会学術講演会プログラム・抄録集　Vol. 63回　p. 204-204　2021/07

ベバシズマブ投与はmiR-107およびmiR-365 a-3p発現をダウンレギュレートし卵巣がんの血管新生因子であるIL-6のアップレギュレートを促進する(Bevacizumab Treatment Down-regulates miR-107 and miR-365 a-3p Expression, Both of Which Promote IL-6 Up-regulation Leading to Alternative Angiogenesis in Ovarian Cancer)

八木 太郎, 澤田 健二郎, 宮本 真由子, 中村 幸司, 木瀬 康人, 木村 正

日本婦人科腫瘍学会学術講演会プログラム・抄録集　Vol. 63回　p. 204-204　2021/07

エクソソームCD47は卵巣癌の進行過程における腫瘍免疫回避に重要な役割を果たす(Exosomal CD47 Plays a Crucial Role in Tumor Immune Evasion during Ovarian Cancer Progression)

清水 亜麻, 澤田 健二郎, 八木 太郎, 山本 実咲, 中村 幸司, 木瀬 康人, 木村 正

日本婦人科腫瘍学会学術講演会プログラム・抄録集　Vol. 63回　p. 206-206　2021/07

血漿中に微量に存在するPIK3CA変異を検出することで血漿中セルフリーDNAにより卵巣癌と良性子宮内膜症性嚢胞の鑑別は可能である(Plasma Cell Free DNA can Discriminate Ovarian Cancer from Benign Endometriotic Cysts by Detecting PIK3CA Mutation Faintly Existing in Plasma)

山本 実咲, 澤田 健二郎, 清水 亜麻, 中村 幸司, 木瀬 康人, 小玉 美智子, 橋本 香映, 木村 正

日本婦人科腫瘍学会学術講演会プログラム・抄録集　Vol. 63回　p. 234-234　2021/07

Subsequent menstrual disorder after spontaneous menarche in Turner syndrome.

Naoko Komura, Seiji Mabuchi, Kenjiro Sawada, Yukihiro Nishio, Tadashi Kimura, Hiroko Komura

Clinical endocrinology　Vol. 95　No. 1　p. 163-168　2021/07　Research paper (scientific journal)

Exosomal CD47 Plays an Essential Role in Immune Evasion in Ovarian Cancer.

Aasa Shimizu, Kenjiro Sawada, Masaki Kobayashi, Misa Yamamoto, Taro Yagi, Yasuto Kinose, Michiko Kodama, Kae Hashimoto, Tadashi Kimura

Molecular cancer research : MCR　Vol. 19　No. 9　p. 1583-1595　2021/05/20　Research paper (scientific journal)

Dose rate in the highest irradiation area of the rectum correlates with late rectal complications in patients treated with high-dose-rate computed tomography-based image-guided brachytherapy for cervical cancer.

Fumiaki Isohashi, Yuichi Akino, Yuri Matsumoto, Osamu Suzuki, Yuji Seo, Keisuke Tamari, Iori Sumida, Kenjiro Sawada, Yutaka Ueda, Eiji Kobayashi, Takuji Tomimatsu, Erina Nakanishi, Takahisa Nishi, Tadashi Kimura, Kazuhiko Ogawa

Journal of radiation research　Vol. 62　No. 3　p. 494-501　2021/05/12　Research paper (scientific journal)

Ubiquitin specific peptidase 32 acts as an oncogene in epithelial ovarian cancer by deubiquitylating farnesyl-diphosphate farnesyltransferase 1.

Aya Nakae, Michiko Kodama, Toru Okamoto, Makoto Tokunaga, Hiroko Shimura, Kae Hashimoto, Kenjiro Sawada, Takahiro Kodama, Neal G Copeland, Nancy A Jenkins, Tadashi Kimura

Biochemical and biophysical research communications　Vol. 552　p. 120-127　2021/05/07　Research paper (scientific journal)

Prognostic significance of bone marrow FDG uptake in patients with gynecological cancer.

Kotaro Shimura, Seiji Mabuchi, Naoko Komura, Eriko Yokoi, Katsumi Kozasa, Tomoyuki Sasano, Mahiru Kawano, Yuri Matsumoto, Tadashi Watabe, Michiko Kodama, Kae Hashimoto, Kenjiro Sawada, Jun Hatazawa, Tadashi Kimura

Scientific reports　Vol. 11　No. 1　p. 2257-2257　2021/01/26　Research paper (scientific journal)

The role of myeloid-derived suppressor cells in increasing cancer stem-like cells and promoting PD-L1 expression in epithelial ovarian cancer.

Naoko Komura, Seiji Mabuchi, Kotaro Shimura, Eriko Yokoi, Katsumi Kozasa, Hiromasa Kuroda, Ryoko Takahashi, Tomoyuki Sasano, Mahiru Kawano, Yuri Matsumoto, Michiko Kodama, Kae Hashimoto, Kenjiro Sawada, Tadashi Kimura

Cancer immunology, immunotherapy : CII　Vol. 69　No. 12　p. 2477-2499　2020/12　Research paper (scientific journal)

【論文作成の戦略-アクセプトを勝ちとるために】いまさら聞けない論文作成のキホン 投稿するジャーナルの選定と査読の流れ 悪徳雑誌(ハゲタカジャーナル)の見分け方

澤田 健二郎

臨床婦人科産科　Vol. 74　No. 11　p. 1126-1134　2020/11

Paclitaxel exposure downregulates miR-522 expression and its downregulation induces paclitaxel resistance in ovarian cancer cells.

Mayuko Miyamoto, Kenjiro Sawada, Koji Nakamura, Akihiko Yoshimura, Kyoso Ishida, Masaki Kobayashi, Aasa Shimizu, Misa Yamamoto, Michiko Kodama, Kae Hashimoto, Tadashi Kimura

Scientific reports　Vol. 10　No. 1　p. 16755-16755　2020/10/07　Research paper (scientific journal)

子宮頸部腺癌治療後のホルモン補充療法

小川 美祈, 橋本 香映, 八木 太郎, 山本 実咲, 清水 亜麻, 中塚 えりか, 木瀬 康人, 澤田 健二郎, 木村 正

日本女性医学学会雑誌　Vol. 28　No. 1　p. 119-119　2020/10

子宮筋腫に対するUAE治療の患者満足度は保険適用により変化したか?

山本 実咲, 澤田 健二郎, 小川 美祈, 八木 太郎, 清水 亜麻, 志村 寛子, 志村 宏太郎, 戸田 有朱香, 木瀬 康人, 木村 正

日本女性医学学会雑誌　Vol. 28　No. 1　p. 156-156　2020/10

Oncological and Reproductive Outcomes of Abdominal Radical Trachelectomy.

A I Yoshino, Eiji Kobayashi, Michiko Kodama, Kae Hashimoto, Yutaka Ueda, Kenjiro Sawada, Takuji Tomimatsu, Tadashi Kimura

Anticancer research　Vol. 40　No. 10　p. 5939-5947　2020/10　Research paper (scientific journal)

Exploring the potential of engineered exosomes as delivery systems for tumor-suppressor microRNA replacement therapy in ovarian cancer.

Masaki Kobayashi, Kenjiro Sawada, Mayuko Miyamoto, Aasa Shimizu, Misa Yamamoto, Yasuto Kinose, Koji Nakamura, Mahiru Kawano, Michiko Kodama, Kae Hashimoto, Tadashi Kimura

Biochemical and biophysical research communications　Vol. 527　No. 1　p. 153-161　2020/06/18　Research paper (scientific journal)

The potential of circulating cell-free tumor DNA as a diagnostic marker of ovarian cancer

Misa Yamamoto, Kenjiro Sawada, Aasa Shimizu, Yuri Matsumoto, Michiko Kodama, Kae Hashimoto, Tadashi Kimura

CLINICAL CANCER RESEARCH　Vol. 26　No. 11　p. 42-42　2020/06

Pathophysiological Role and Potential Therapeutic Exploitation of Exosomes in Ovarian Cancer.

Aasa Shimizu, Kenjiro Sawada, Tadashi Kimura

Cells　Vol. 9　No. 4　2020/03/27　Research paper (scientific journal)

Clinical effects of switching from minodronate to denosumab treatment in patients with postmenopausal osteoporosis: a retrospective study.

Masaki Kobayashi, Kenjiro Sawada, Akihiko Yoshimura, Misa Yamamoto, Aasa Shimizu, Kotaro Shimura, Naoko Komura, Mayuko Miyamoto, Kyoso Ishida, Tadashi Kimura

BMC women's health　Vol. 20　No. 1　p. 48-48　2020/03/05　Research paper (scientific journal)

Indocyanine green is superior to blue colorimetric method for identifying sentinel lymph nodes during laparoscopic surgery for uterine malignancies: a pilot study

Eiji Kobayashi, Mamoru Kakuda, Tuyoshi Takiuchi, Michiko Kodama, Mayu Shiomi, Saori Kakuda, Yutaka Ueda, Kenjiro Sawada, Takuji Tomimatsu, Kiyoshi Yoshino, Tadashi Kimura

European Journal of Gynaecological Oncology　Vol. 41　No. 2　p. 176-176　2020　Research paper (scientific journal)

The role of myeloid-derived suppressor cells in endometrial cancer displaying systemic inflammatory response: clinical and preclinical investigations

Eriko Yokoi, Seiji Mabuchi, Naoko Komura, Kotaro Shimura, Hiromasa Kuroda, Katsumi Kozasa, Ryoko Takahashi, Tomoyuki Sasano, Mahiru Kawano, Yuri Matsumoto, Michiko Kodama, Kae Hashimoto, Kenjiro Sawada, Tadashi Kimura

ONCOIMMUNOLOGY　Vol. 8　No. 12　2019/12　Research paper (scientific journal)

Therapeutic potential of microRNAs in the regulation of cancer energy metabolism.

Misa Yamamoto, Kenjiro Sawada, Tadashi Kimura

Annals of translational medicine　Vol. 7　No. Suppl 8　2019/12

Direct oral anticoagulants are effective and safe for the treatment of venous thromboembolism associated with gynecological cancers.

Aasa Shimizu, Kenjiro Sawada, Mayu Shiomi, Mahiru Kawano, Yuri Matsumoto, Tsuyoshi Takiuchi, Michiko Kodama, Eiji Kobayashi, Kae Hashimoto, Seiji Mabuchi, Yutaka Ueda, Takuji Tomimatsu, Tadashi Kimura

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics　Vol. 147　No. 2　p. 252-257　2019/11　Research paper (scientific journal)

Correction: Heterotypic CAF-tumor spheroids promote early peritoneal metastatis of ovarian cancer.

Qinglei Gao, Zongyuan Yang, Sen Xu, Xiaoting Li, Xin Yang, Ping Jin, Yi Liu, Xiaoshui Zhou, Taoran Zhang, Cheng Gong, Xiao Wei, Dan Liu, Chaoyang Sun, Gang Chen, Junbo Hu, Li Meng, Jianfeng Zhou, Kenjiro Sawada, Robert Fruscio, Thomas W Grunt, Jörg Wischhusen, Víctor Manuel Vargas-Hernández, Bhavana Pothuri, Robert L Coleman

The Journal of experimental medicine　Vol. 216　No. 10　p. 2448-2448　2019/10/07　Research paper (scientific journal)

Lurbinectedin (PM01183), a selective inhibitor of active transcription, effectively eliminates both cancer cells and cancer stem cells in preclinical models of uterine cervical cancer

Eriko Yokoi, Seiji Mabuchi, Kotaro Shimura, Naoko Komura, Katsumi Kozasa, Hiromasa Kuroda, Ryoko Takahashi, Tomoyuki Sasano, Mahiru Kawano, Yuri Matsumoto, Michiko Kodama, Kae Hashimoto, Kenjiro Sawada, Tadashi Kimura

INVESTIGATIONAL NEW DRUGS　Vol. 37　No. 5　p. 818-827　2019/10　Research paper (scientific journal)

Role of the Exosome in Ovarian Cancer Progression and Its Potential as a Therapeutic Target.

Koji Nakamura, Kenjiro Sawada, Masaki Kobayashi, Mayuko Miyamoto, Aasa Shimizu, Misa Yamamoto, Yasuto Kinose, Tadashi Kimura

Cancers　Vol. 11　No. 8　2019/08/10　Research paper (scientific journal)

The development of a novel microRNA replacement therapy for ovarian cancer - a potential of patient derived-exosomes as a carrier

Masaki Kobayashi, Kenjiro Sawada, Aasa Shimizu, Mayuko Miyamoto, Erika Nakatsuka, Mahiru Kawano, Yuri Matsumoto, Michiko Kodama, Kae Hashimoto, Seiji Mabuchi, Tadashi Kimura

CANCER RESEARCH　Vol. 79　No. 13　2019/07

Estrogen stimulates female cancer progression by inducing myeloid-derived suppressive cells: investigations on pregnant and non-pregnant experimental models.

Katsumi Kozasa, Seiji Mabuchi, Yuri Matsumoto, Hiromasa Kuroda, Eriko Yokoi, Naoko Komura, Mahiru Kawano, Ryoko Takahashi, Tomoyuki Sasano, Kotaro Shimura, Michiko Kodama, Kae Hashimoto, Kenjiro Sawada, Kazunori Nagasaka, Tadashi Kimura

Oncotarget　Vol. 10　No. 20　p. 1887-1902　2019/03/08　Research paper (scientific journal)

A 3-year follow-up study of radiotherapy using computed tomography-based image-guided brachytherapy for cervical cancer

Atsushi Kawashima, Fumiaki Isohashi, Seiji Mabuchi, Kenjiro Sawada, Yutaka Ueda, Eiji Kobayashi, Yuri Matsumoto, Keisuke Otani, Keisuke Tamari, Yuji Seo, Osamu Suzuki, Iori Sumida, Takuji Tomimatsu, Tadashi Kimura, Kazuhiko Ogawa

JOURNAL OF RADIATION RESEARCH　Vol. 60　No. 2　p. 264-269　2019/03　Research paper (scientific journal)

Heterotypic CAF-tumor spheroids promote early peritoneal metastatis of ovarian cancer

Qinglei Gao, Zongyuan Yang, Sen Xu, Xiaoting Li, Xin Yang, Ping Jin, Yi Liu, Xiaoshui Zhou, Taoran Zhang, Cheng Gong, Xiao Wei, Dan Liu, Chaoyang Sun, Gang Chen, Junbo Hu, Li Meng, Jianfeng Zhou, Kenjiro Sawada, Robert Fruscio, Thomas W. Grunt, Jorg Wischhusen, Victor Manuel Vargas-Hernandez, Bhavana Pothuri, Robert L. Coleman

JOURNAL OF EXPERIMENTAL MEDICINE　Vol. 216　No. 3　p. 688-703　2019/03　Research paper (scientific journal)

A phase II study of irinotecan combined with S-1 in patients with advanced or recurrent cervical cancer previously treated with platinum based chemotherapy.

Seiji Mabuchi, Eriko Yokoi, Kotaro Shimura, Naoko Komura, Yuri Matsumoto, Kenjiro Sawada, Aki Isobe, Tateki Tsutsui, Fuminori Kitada, Tadashi Kimura

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society　Vol. 29　No. 3　p. 474-479　2019/03　Research paper (scientific journal)

Downregulation of miR-194-5p induces paclitaxel resistance in ovarian cancer cells by altering MDM2 expression.

Koji Nakamura, Kenjiro Sawada, Mayuko Miyamoto, Yasuto Kinose, Akihiko Yoshimura, Kyoso Ishida, Masaki Kobayashi, Aasa Shimizu, Erika Nakatsuka, Kae Hashimoto, Seiji Mabuchi, Tadashi Kimura

Oncotarget　Vol. 10　No. 6　p. 673-683　2019/01/18　Research paper (scientific journal)

Development of novel approaches to detect ovarian cancer recurrence

Aasa Shimizu, Kenjiro Sawada, Tadashi Kimura

Journal of Medical Artificial Intelligence　Vol. 2　No. March　2019　Research paper (scientific journal)

Serum miR-1290 is correlated with high grade serous epithelial ovarian cancer and can be a new potential biomarker

Masaki Kobayashi, Kenjiro Sawada, Mayuko Miyamoto, Akihiko Yoshimura, Erika Nakatsuka, Koji Nakamura, Seiji Mabuchi, Tadashi Kimura

CANCER SCIENCE　Vol. 109　p. 392-392　2018/12

Sleeping Beauty transposon mutagenesis screen of uterine leiomyosarcoma identifies driver genes of sarcomagenesis

Michiko Kodama, Aya Nakae, Hiroko Shimura, Kae Hashimoto, Seiji Mabuchi, Kenjiro Sawada, Tadashi Kimura

CANCER SCIENCE　Vol. 109　p. 1169-1169　2018/12

Myeloid derived suppressor cells (MDSC) increase cancer stem cells (CSC) and tumor PD-L1 expression in ovarian cancer

Naoko Komura, Seiji Mabuchi, Kotaro Shimura, Eriko Yokoi, Michiko Kodama, Kae Hashimoto, Kenjiro Sawada, Tadashi Kimura

CANCER SCIENCE　Vol. 109　p. 750-750　2018/12

Low miR-522 expression is related to paclitaxel resistance in ovarian cancer cells

Mayuko Miyamoto, Kenjiro Sawada, Koji Nakamura, Masaki Kobayashi, Seiji Mabuchi, Tadashi Kimura

CANCER SCIENCE　Vol. 109　p. 392-392　2018/12

Ovarian cancer exosome promotes cancer invasion by affecting peritoneal mesothelial cells and can work as a biomarker

Kenjiro Sawada, Masaki Kobayashi, Koji Nakamura, Akihiko Yoshimura, Tadashi Kimura

CANCER SCIENCE　Vol. 109　p. 621-621　2018/12

Myeloid-derived suppressor cells (MDSC) induce cancer stem cells (CSC) in G-CSF producing endometrial cancer

Eriko Yokoi, Seiji Mabuchi, Kotaro Shimura, Naoko Komura, Michiko Kodama, Kae Hashimoto, Kenjiro Sawada, Tadashi Kimura

CANCER SCIENCE　Vol. 109　p. 488-488　2018/12

Prostaglandin E2 produced by myeloid-derived suppressive cells induces cancer stem cells in uterine cervical cancer.

Hiromasa Kuroda, Seiji Mabuchi, Eriko Yokoi, Naoko Komura, Katsumi Kozasa, Yuri Matsumoto, Mahiru Kawano, Ryoko Takahashi, Tomoyuki Sasano, Kotaro Shimura, Michiko Kodama, Kae Hashimoto, Kenjiro Sawada, Eiichi Morii, Tadashi Kimura

Oncotarget　Vol. 9　No. 91　p. 36317-36330　2018/11/20　Research paper (scientific journal)

Exosomal miR-99a-5p is elevated in sera of ovarian cancer patients and promotes cancer cell invasion by increasing fibronectin and vitronectin expression in neighboring peritoneal mesothelial cells

Akihiko Yoshimura, Kenjiro Sawada, Koji Nakamura, Yasuto Kinose, Erika Nakatsuka, Masaki Kobayashi, Mayuko Miyamoto, Kyoso Ishida, Yuri Matsumoto, Michiko Kodama, Kae Hashimoto, Seiji Mabuchi, Tadashi Kimura

BMC CANCER　Vol. 18　No. 1　p. 1065-1065　2018/11　Research paper (scientific journal)

A phase I/II study of GLIF combination chemotherapy for taxane/platinum-refractory/resistant endometrial cancer (GOGO-EM2)

Yusuke Tanaka, Yutaka Ueda, Satoshi Nakagawa, Shinya Matsuzaki, Eiji Kobayashi, Yasuhiko Shiki, Yukihiro Nishio, Masahiko Takemura, Toshiya Yamamoto, Kenjiro Sawada, Takuji Tomimatsu, Kiyoshi Yoshino, Tadashi Kimura

CANCER CHEMOTHERAPY AND PHARMACOLOGY　Vol. 82　No. 4　p. 585-592　2018/10　Research paper (scientific journal)

Is microRNA replacement therapy promising treatment for cancer?

Kobayashi, M. Sawada, K, Kimura, T

Non-coding RNA Investig　2018/09　Research paper (scientific journal)

Exosomal miR-1290 is a potential of high-grade serous ovarian carcinoma and can discriminate patients from those with malignancies of other histological types

Masaki Kobayashi, Kenjiro Sawada, Koji Nakamura, Akihiko Yoshimura, Mayuko Miyamoto, Aasa Shimizu, Kyoso Ishida, Erika Nakatsuka, Michiko Kodama, Kae Hashimoto, Seiji Mabuchi, Tadashi Kimura

JOURNAL OF OVARIAN RESEARCH　Vol. 11　No. 1　p. 81-81　2018/09　Research paper (scientific journal)

The Highly Metastatic Nature of Uterine Cervical/Endometrial Cancer Displaying Tumor-Related Leukocytosis: Clinical and Preclinical Investigations

Tomoyuki Sasano, Seiji Mabuchi, Katsumi Kozasa, Hiromasa Kuroda, Mahiru Kawano, Ryoko Takahashi, Naoko Komura, Eriko Yokoi, Yuri Matsumoto, Kae Hashimoto, Kenjiro Sawada, Eiichi Morii, Tadashi Kimura

CLINICAL CANCER RESEARCH　Vol. 24　No. 16　p. 4018-4029　2018/08　Research paper (scientific journal)

Elevated level of serum miR-1290 is correlated with high-grade serous ovarian epithelial ovarian cancer and might be a potential biomarker

Masaki Kobayashi, Sawada Kenjiro, Yoshimura Akihiko, Miyamoto Mayuko, Nakatsuka Erika, Kodama Michiko, Hashimoto Kae, Mabuchi Seiji, Kimura Tadashi

CANCER RESEARCH　Vol. 78　No. 13　2018/07

Sleeping Beauty transposon mutagenesis screen identifies cancer genes of uterine leiomyosarcoma driving sarcomagenesis and lung metastasis

Michiko Kodama, Takahiro Kodama, Justin Y. Newberg, Jean C. Tien, Roberto Rangel, Aya Nakae, Kae Hashimoto, Seiji Mabuchi, Kenjiro Sawada, Tadashi Kimura, Nancy A. Jenkins, Neal G. Copeland

CANCER RESEARCH　Vol. 78　No. 13　2018/07

Low miR-522 expression is correlated with paclitaxel resistance in ovarian cancer cells

Mayuko Miyamoto, Kenjiro Sawada, Akihiko Yoshimura, Erika Nakatsuka, Michiko Kodama, Kae Hashimoto, Seiji Mabuchi, Tadashi Kimura

CANCER RESEARCH　Vol. 78　No. 13　2018/07

In vivo dropout screens identified new drug targets for epithelial ovarian cancer

Michiko Kodama, Takahiro Kodama, Kosuke Yoshihara, Kae Hashimoto, Seiji Mabuchi, Kenjiro Sawada, Tadashi Kimura

CANCER SCIENCE　Vol. 109　p. 565-565　2018/01

Elevated level of serum miR-99a-5p is correlated with ovarian cancer and can be a potential biomarker.

Akihiko Yoshimura, Kenjiro Sawada, Koji Nakamura, Yasuto Kinose, Erika Nakatsuka, Seiji Mabuchi, Tadashi Kimura

CANCER SCIENCE　Vol. 109　p. 598-598　2018/01

Effect of Japanese Kampo Medicine Therapy for Menopausal Symptoms after Treatment of Gynecological Malignancy

Akihiko Yoshimura, Kenjiro Sawada, Tomoyuki Sasano, Hiromasa Kuroda, Katsumi Kozasa, Erika Nakatsuka, Koji Nakamura, Kae Hashimoto, Seiji Mabuchi, Tadashi Kimura

OBSTETRICS AND GYNECOLOGY INTERNATIONAL　Vol. 2018　p. 9475919-9475919　2018　Research paper (scientific journal)

子宮筋腫・子宮腺筋症

澤田健二郎

今日の治療指針～私はこう治療している～　2018/01　Research paper (scientific journal)

Ovarian Hyperstimulation Syndrome Due to Exogenous Human Chorionic Gonadotropin (hCG) Presenting More Than 7 Days After hCG Administration

Kobayashi M, Kumasawa K, Koizumi K, Takiuchi T, Nakamura H, Sawada K, Kimura T

Journal of Gynecology and Obstetrics　2018/01　Research paper (scientific journal)

Ovarian hyperstimulation syndrome due to exogenous human chorionic gonadotropin(hCG) presenting more than 7 days after hCG administration

Kobayashi, M. Kumasawa, K. Koizumi, K. Takiuchi, T. Nakamura, H. Sawada, K, Kimura, T

Gynecol Obstet　Vol. 5　p. 78-80　2017/12　Research paper (scientific journal)

Combination chemotherapy with irinotecan and gemcitabine for taxane/platinum-resistant/refractory ovarian and primary peritoneal cancer: a multicenter phase I/II trial (GOGO-Ov 6)

Kiyoshi Yoshino, Shoji Kamiura, Takeshi Yokoi, Ruriko Nakae, Masami Fujita, Masahiko Takemura, Kazushige Adachi, Akinori Wakimoto, Takamichi Nishizaki, Yasuhiko Shiki, Tateki Tsutsui, Yuki Kanda, Eiji Kobayashi, Kae Hashimoto, Seiji Mabuchi, Yutaka Ueda, Kenjiro Sawada, Takuji Tomimatsu, Tadashi Kimura

CANCER CHEMOTHERAPY AND PHARMACOLOGY　Vol. 80　No. 6　p. 1239-1247　2017/12　Research paper (scientific journal)

A case of laparoscopic surgery for endometrial cancer in a patient previously treated with a transvaginal mesh procedure for pelvic organ prolapse

Kiyoshi Yoshino, Eiji Kobayashi, Masayuki Endo, Mamoru Kakuda, Aiko Okada, Takuji Tomimatsu, Kenjiro Sawada, Masahiko Takemura, Tadashi Kimura

GYNECOLOGY AND MINIMALLY INVASIVE THERAPY-GMIT　Vol. 6　No. 4　p. 211-213　2017/11　Research paper (scientific journal)

Plasminogen activator inhibitor-1 is an independent prognostic factor of ovarian cancer and IMD-4482, a novel plasminogen activator inhibitor-1 inhibitor, inhibits ovarian cancer peritoneal dissemination

Erika Nakatsuka, Kenjiro Sawada, Koji Nakamura, Akihito Yoshimura, Yasuto Kinose, Michiko Kodama, Kae Hashimoto, Seiji Mabuchi, Hiroshi Makino, Eiichi Morii, Yoichi Yamaguchi, Takeshi Yanase, Akiko Itai, Ken-ichirou Morishige, Tadashi Kimura

ONCOTARGET　Vol. 8　No. 52　p. 89887-89902　2017/10　Research paper (scientific journal)

Predictors for recurrent/persistent high-grade intraepithelial lesions and cervical stenosis after therapeutic conization: a retrospective analysis of 522 cases

Yusuke Tanaka, Yutaka Ueda, Mamoru Kakuda, Satoshi Kubota, Satoko Matsuzaki, Tadashi Iwamiya, Akiko Okazawa, Shinya Matsuzaki, Kae Hashimoto, Eiji Kobayashi, Seiji Mabuchi, Kenjiro Sawada, Takuji Tomimatsu, Kiyoshi Yoshino, Tadashi Kimura

INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY　Vol. 22　No. 5　p. 921-926　2017/10　Research paper (scientific journal)

PM01183 inhibits myeloid-derived suppressor cells in vitro and in vivo

Hiromasa Kuroda, Seiji Mabuchi, Katsumi Kozasa, Eriko Yokoi, Yuri Matsumoto, Naoko Komura, Mahiru Kawano, Kae Hashimoto, Kenjiro Sawada, Tadashi Kimura

IMMUNOTHERAPY　Vol. 9　No. 10　p. 805-817　2017/09　Research paper (scientific journal)

In vivo loss-of-function screens identify KPNB1 as a new druggable oncogene in epithelial ovarian cancer

Michiko Kodama, Takahiro Kodama, Justin Y. Newberg, Hiroyuki Katayama, Makoto Kobayashi, Samir M. Hanash, Kosuke Yoshihara, Zhubo Wei, Jean C. Tien, Roberto Rangel, Kae Hashimoto, Seiji Mabuchi, Kenjiro Sawada, Tadashi Kimura, Neal G. Copeland, Nancy A. Jenkins

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA　Vol. 114　No. 35　p. E7301-E7310　2017/08　Research paper (scientific journal)

In vivo pooled shRNA library identifies KPNB1 as a new drug target for epithelial ovarian cancer

Michiko Kodama, Takahiro Kodama, Kosuke Yoshihara, Kae Hashimoto, Seiji Mabuchi, Kenjiro Sawada, Tadashi Kimura, Neal Copeland, Nancy Jenkins

CANCER RESEARCH　Vol. 77　2017/07

MiR-194 modulates paclitaxel resistance in ovarian cancer cells through the regulation of MDM-2 expression

Koji Nakamura, Kenjiro Sawada, Akihiko Yoshimura, Erica Nakatsuka, Yasuto Kinose, Seiji Mabuchi, Tadashi Kimura

CANCER RESEARCH　Vol. 77　2017/07

Elevated level of serum miR-99a is correlated with serous epithelial ovarian cancer and can be a potential biomarker

Akihiko Yoshimura, Kenjiro Sawada, Koji Nakamura, Yasuto Kinose, Erika Nakatsuka, Seiji Mabuchi, Tadashi Kimura

CANCER RESEARCH　Vol. 77　2017/07

Potential of Integrin Inhibitors for Treating Ovarian Cancer: A Literature Review

Masaki Kobayashi, Kenjiro Sawada, Tadashi Kimura

CANCERS　Vol. 9　No. 7　2017/07　Research paper (scientific journal)

The significance of tumor-associated neutrophil density in uterine cervical cancer treated with definitive radiotherapy

Yuri Matsumoto, Seiji Mabuchi, Katsumi Kozasa, Hiromasa Kuroda, Tomoyuki Sasano, Eriko Yokoi, Naoko Komura, Kenjiro Sawada, Tadashi Kimura

GYNECOLOGIC ONCOLOGY　Vol. 145　No. 3　p. 469-475　2017/06　Research paper (scientific journal)

Is the exosome a potential target for cancer immunotherapy?

Akihiko Yoshimura, Kenjiro Sawada, Tadashi Kimura

ANNALS OF TRANSLATIONAL MEDICINE　Vol. 5　No. 5　p. 117-117　2017/03　Research paper (scientific journal)

Is the exosome a potential target for cancer immunotherapy?

Yoshimura, A. Sawada, K, Kimura, T

Annals of translational medicine　Vol. 5　2017/03　Research paper (scientific journal)

Ovarian insufficiency following allogeneic hematopoietic stem cell transplantation.

Mahiru Kawano, Hiroko Komura, Haruna Kawaguchi, Shoko Shimizu, Namiko Yada-Hashimoto, Mariko Shimizu, Maho Sato, Masami Inoue, Shinobu Ida, Yuri Etani, Yasuko Shoji, Mariko Nakacho, Kenjiro Sawada, Tadashi Kimura, Nobuaki Mitsuda, Hirohisa Kurachi

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology　Vol. 33　No. 2　p. 156-159　2017/02　Research paper (scientific journal)

Ovarian insufficiency following allogeneic hematopoietic stem cell transplantation

Mahiru Kawano, Hiroko Komura, Haruna Kawaguchi, Shoko Shimizu, Namiko Yada-Hashimoto, Mariko Shimizu, Maho Sato, Masami Inoue, Shinobu Ida, Yuri Etani, Yasuko Shoji, Mariko Nakacho, Kenjiro Sawada, Tadashi Kimura, Nobuaki Mitsuda, Hirohisa Kurachi

GYNECOLOGICAL ENDOCRINOLOGY　Vol. 33　No. 2　p. 156-159　2017/02　Research paper (scientific journal)

Pure Primary Ovarian Squamous Cell Carcinoma Perforating the Rectum.

Kazuya Mimura, Aiko Okada, Naotsugu Haraguchi, Kenjiro Sawada, Takuji Tomimatsu, Tadashi Kimura

Case reports in obstetrics and gynecology　Vol. 2017　p. 9793086-9793086　2017　Research paper (scientific journal)

Effects of minodronate in postmenopausal women with osteoporosis who received prior treatment with raloxifene

Aska Toda, Kenjiro Sawada, Akihiko Yoshimura, Erika Nakatsuka, Hiromasa Kuroda, Katsumi Kozasa, Mayuko Miyamoto, Kae Hashimoto, Seiji Mabuchi, Tadashi Kimura

INTERNATIONAL JOURNAL OF WOMENS HEALTH　Vol. 9　p. 821-825　2017　Research paper (scientific journal)

Exosomes Promote Ovarian Cancer Cell Invasion through Transfer of CD44 to Peritoneal Mesothelial Cells

Koji Nakamura, Kenjiro Sawada, Yasuto Kinose, Akihiko Yoshimura, Aska Toda, Erika Nakatsuka, Kae Hashimoto, Seiji Mabuchi, Ken-ichirou Morishige, Hirohisa Kurachi, Ernst Lengyel, Tadashi Kimura

MOLECULAR CANCER RESEARCH　Vol. 15　No. 1　p. 78-92　2017/01　Research paper (scientific journal)

Dose-volume analysis of predictors for chronic gastrointestinal complications in patients with cervical cancer treated with postoperative concurrent chemotherapy and whole-pelvic radiation therapy

Fumiaki Isohashi, Seiji Mabuchi, Yuichi Akino, Yasuo Yoshioka, Yuji Seo, Osamu Suzuki, Keisuke Tamari, Kiyoshi Yoshino, Kenjiro Sawada, Yutaka Ueda, Eiji Kobayashi, Iori Sumida, Hirokazu Mizuno, Hirofumi Okubo, Tadashi Kimura, Kazuhiko Ogawa

JOURNAL OF RADIATION RESEARCH　Vol. 57　No. 6　p. 668-676　2016/11　Research paper (scientific journal)

TARGETING IKK beta PREVENTS INFLAMMATION-INDUCED PRETERM DELIVERY BY INHIBITING INTERLEUKIN-6 PRODUCTION FROM AMNIOTIC CELLS

Aska Toda, Kenjiro Sawada, Akiko Itai, Tadashi Kimura

PLACENTA　Vol. 46　p. 116-116　2016/10

Crucial role of vascular endothelial growth factor in the immune system of patients with ovarian cancer

Yasuto Kinose, Kenjiro Sawada, Tadashi Kimura

TRANSLATIONAL CANCER RESEARCH　Vol. 5　p. S269-S271　2016/08　Research paper (scientific journal)

Exosomes promote ovarian cancer invasion through CD-44 transfer to mesothelial cells

Koji Nakamura, Kenjiro Sawada, Yasuto Kinose, Akihiko Yoshimura, Erika Nakatsuka, Seiji Mabuchi, Tadashi Kimura

CANCER RESEARCH　Vol. 76　2016/07

Single‑dose intra‑arterial neoadjuvant chemotherapy while waiting for radical hysterectomy for stage IB‑IIB cervical cancer

Kiyoshi Yoshino, Ayako Hosoi, Keigo Osuga, Takayuki Enomoto, Yutaka Ueda, Kenjiro Sawada, Seiji Mabuchi, Eiji Kobayashi, Koji Matsuo, Tadashi Kimura

Mol Clin Oncol　2016/06　Research paper (scientific journal)

Clinical relevance of circulating cell-free microRNAs in ovarian cancer

Koji Nakamura, Kenjiro Sawada, Akihiko Yoshimura, Yasuto Kinose, Erika Nakatsuka, Tadashi Kimura

MOLECULAR CANCER　Vol. 15　No. 1　p. 48-48　2016/06　Research paper (scientific journal)

Single-dose intra-arterial neoadjuvant chemotherapy while waiting for radical hysterectomy for stage IB-IIB cervical cancer

Kiyoshi Yoshino, Ayako Hosoi, Keigo Osuga, Takayuki Enomoto, Yutaka Ueda, Kenjiro Sawada, Seiji Mabuchi, Eiji Kobayashi, Koji Matsuo, Tadashi Kimura

MOLECULAR AND CLINICAL ONCOLOGY　Vol. 4　No. 6　p. 1068-1072　2016/06　Research paper (scientific journal)

The Novel I kappa B Kinase beta Inhibitor, IMD-0560, Has Potent Therapeutic Efficacy in Ovarian Cancer Xenograft Model Mice

Ikuko Sawada, Kae Hashimoto, Kenjiro Sawada, Yasuto Kinose, Koji Nakamura, Aska Toda, Erika Nakatsuka, Akihiko Yoshimura, Seiji Mabuchi, Tomoyuki Fujikawa, Akiko Itai, Tadashi Kimura

INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER　Vol. 26　No. 4　p. 610-618　2016/05　Research paper (scientific journal)

Targeting Inhibitor of kappa B Kinase beta Prevents Inflammation-Induced Preterm Delivery by Inhibiting IL-6 Production from Amniotic Cells

Aska Toda, Kenjiro Sawada, Tomoyuki Fujikawa, Atsuko Wakabayashi, Koji Nakamura, Ikuko Sawada, Akihiko Yoshimura, Erika Nakatsuka, Yasuto Kinose, Kae Hashimoto, Seiji Mabuchi, Atsushi Tokuhira, Masahiro Nakayama, Akiko Itai, Hirohisa Kurachi, Tadashi Kimura

AMERICAN JOURNAL OF PATHOLOGY　Vol. 186　No. 3　p. 616-629　2016/03　Research paper (scientific journal)

Preclinical Investigations of PM01183 (Lurbinectedin) as a Single Agent or in Combination with Other Anticancer Agents for Clear Cell Carcinoma of the Ovary

Ryoko Takahashi, Seiji Mabuchi, Mahiru Kawano, Tomoyuki Sasano, Yuri Matsumoto, Hiromasa Kuroda, Katsumi Kozasa, Kae Hashimoto, Kenjiro Sawada, Tadashi Kimura

PLOS ONE　Vol. 11　No. 3　2016/03　Research paper (scientific journal)

The Novel IκB Kinase β Inhibitor, IMD-0561, Has Potent Therapeutic Efficacy in Ovarian Cancer Xenograft ModelMice.

Sawada, I. Hashimoto, K. Sawada, K. Kinose, Y. Nakamura, K. Toda, A. Nakatsuka, E. Yoshimura, A. Mabuchi, S. Fujikawa, T. Itai, A. Kimura, T

Int J Gynecol Cancer　2016/02　Research paper (scientific journal)

Postoperative administration of dienogest for suppressing recurrence of disease and relieving pain in subjects with ovarian endometriomas

Kazushige Adachi, Kayo Takahashi, Koji Nakamura, Akiko Otake, Naoko Sasamoto, Yukari Miyoshi, Mitsunori Shioji, Yoshimitsu Yamamoto, Mayumi Fujitani, Akinori Wakimoto, Atsushi Tokuhira, Eiji Kobayashi, Akihiko Yoshimura, Kenjiro Sawada, Tadashi Kimura

GYNECOLOGICAL ENDOCRINOLOGY　Vol. 32　No. 8　p. 646-649　2016　Research paper (scientific journal)

Efficacies of uterine artery embolization for symptomatic uterine fibroids using gelatin sponge: a single-center experience and literature review

Aska Toda, Kenjiro Sawada, Keigo Osuga, Noboru Maeda, Hiroki Higashihara, Tomoyuki Sasano, Noriyuki Tomiyama, Tadashi Kimura

INTERNATIONAL JOURNAL OF WOMENS HEALTH　Vol. 8　p. 397-404　2016　Research paper (scientific journal)

The significance of lymphatic space invasion and its association with vascular endothelial growth factor-C expression in ovarian cancer

Takeshi Hisamatsu, Seiji Mabuchi, Tomoyuki Sasano, Hiromasa Kuroda, Ryoko Takahashi, Yuri Matsumoto, Mahiru Kawano, Katsumi Kozasa, Kei Takahashi, Kenjiro Sawada, Koji Matsuo, Yutaka Tamada, Eiichi Morii, Yasuhiko Kitadai, Tadashi Kimura

CLINICAL & EXPERIMENTAL METASTASIS　Vol. 32　No. 8　p. 789-798　2015/12　Research paper (scientific journal)

The significance of G-CSF expression and myeloid-derived suppressor cells in the chemoresistance of uterine cervical cancer

Mahiru Kawano, Seiji Mabuchi, Yuri Matsumoto, Tomoyuki Sasano, Ryoko Takahashi, Hiromasa Kuroda, Katsumi Kozasa, Kae Hashimoto, Aki Isobe, Kenjiro Sawada, Toshimitsu Hamasaki, Eiichi Morii, Tadashi Kimura

SCIENTIFIC REPORTS　Vol. 5　2015/12　Research paper (scientific journal)

Hypoxia-related microRNA, miR-199a-3p, displays tumor suppressor function in ovarian cancer

Yasuto Kinose, Kenjiro Sawada, Koji Nakamura, Akihiko Yoshimura, Erika Nakatsuka, Seiji Mabuchi, Tadashi Kimura

CANCER RESEARCH　Vol. 75　2015/08

Exosome transfer from ovarian cancer cells to mesothelial cells promotes cell invasion by upregulating MMP-9 secretion and increasing clearance of mesothelial cells

Koji Nakamura, Kenjiro Sawada, Yasuto Kinose, Akihiko Yoshimura, Erika Nakatsuka, Seiji Mabuchi, Tadashi Kimura

CANCER RESEARCH　Vol. 75　2015/08

Granulocyte-colony stimulating factor (G-CSF) facilitates metastasis of uterine cervical cancer by recruiting myeloid-derived suppressor cells (MDSCs) via CXCL12-CXCR4 axis

Tomoyuki Sasano, Seiji Mabuchi, Ryoko Takahashi, Hiromasa Kuroda, Kenjiro Sawada, Tadashi Kimura

CANCER RESEARCH　Vol. 75　2015/08

Laparoscopic Excisional Surgery for Growing Teratoma Syndrome of the Ovary: Case Report and Literature Review

Naoya Shigeta, Eiji Kobayashi, Kenjiro Sawada, Yutaka Ueda, Kiyoshi Yoshino, Yumiko Hori, Tadashi Kimura

JOURNAL OF MINIMALLY INVASIVE GYNECOLOGY　Vol. 22　No. 4　p. 668-674　2015/05　Research paper (scientific journal)

The hypoxia-related microRNA miR-199a-3p displays tumor suppressor functions in ovarian carcinoma

Yasuto Kinose, Kenjiro Sawada, Koji Nakamura, Ikuko Sawada, Aska Toda, Erika Nakatsuka, Kae Hashimoto, Seiji Mabuchi, Kazuhiro Takahashi, Hirohisa Kurachi, Ernst Lengyel, Tadashi Kimura

ONCOTARGET　Vol. 6　No. 13　p. 11342-11356　2015/05　Research paper (scientific journal)

Preclinical Efficacy for AKT Targeting in Clear Cell Carcinoma of the Ovary

Tomoyuki Sasano, Seiji Mabuchi, Hiromasa Kuroda, Mahiru Kawano, Yuri Matsumoto, Ryoko Takahashi, Takeshi Hisamatsu, Kenjiro Sawada, Kae Hashimoto, Aki Isobe, Joseph R. Testa, Tadashi Kimura

MOLECULAR CANCER RESEARCH　Vol. 13　No. 4　p. 795-806　2015/04　Research paper (scientific journal)

IKK beta Regulates VEGF Expression and Is a Potential Therapeutic Target for Ovarian Cancer as an Antiangiogenic Treatment

Yasuto Kinose, Kenjiro Sawada, Hiroshi Makino, Tomonori Ogura, Tomoko Mizuno, Noriko Suzuki, Tomoyuki Fujikawa, Eiichi Morii, Koji Nakamura, Ikuko Sawada, Aska Toda, Kae Hashimoto, Aki Isobe, Seiji Mabuchi, Tsuyoshi Ohta, Akiko Itai, Ken-ichirou Morishige, Hirohisa Kurachi, Tadashi Kimura

MOLECULAR CANCER THERAPEUTICS　Vol. 14　No. 4　p. 909-919　2015/04　Research paper (scientific journal)

Prognostic significance of systemic neutrophil and leukocyte alterations in surgically treated endometrial cancer patients: A monoinstitutional study

Ryoko Takahashi, Seiji Mabuchi, Mahiru Kawano, Tomoyuki Sasano, Yuri Matsumoto, Hiromasa Kuroda, Takeshi Hisamatsu, Katsumi Kozasa, Kenjiro Sawada, Toshimitsu Hamasaki, Tadashi Kimura

GYNECOLOGIC ONCOLOGY　Vol. 137　No. 1　p. 112-118　2015/04　Research paper (scientific journal)

Optimal Timing for Drainage of Infected Lymphocysts After Lymphadenectomy for Gynecologic Cancer

Kosuke Hiramatsu, Eiji Kobayashi, Yutaka Ueda, Tomomi Egawa-Takata, Shinya Matsuzaki, Toshihiro Kimura, Kenjiro Sawada, Kiyoshi Yoshino, Masami Fujita, Tadashi Kimura

INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER　Vol. 25　No. 2　p. 337-341　2015/02　Research paper (scientific journal)

Interleukin 6 Receptor Is an Independent Prognostic Factor and a Potential Therapeutic Target of Ovarian Cancer

Aki Isobe, Kenjiro Sawada, Yasuto Kinose, Chifumi Ohyagi-Hara, Erika Nakatsuka, Hiroshi Makino, Tomonori Ogura, Tomoko Mizuno, Noriko Suzuki, Eiichi Morii, Koji Nakamura, Ikuko Sawada, Aska Toda, Kae Hashimoto, Seiji Mabuchi, Tsuyoshi Ohta, Ken-ichirou Morishige, Hirohisa Kurachi, Tadashi Kimura

PLOS ONE　Vol. 10　No. 2　2015/02　Research paper (scientific journal)

Efficacy of Raloxifene Hydrochloride for the Prevention of Health Care Problems in Patients Who Undergo Surgery for Endometrial Cancer A Multicenter Randomized Clinical Trial

Koji Nakamura, Kenjiro Sawada, Michiyo Sugiyama, Seiji Mabuchi, Takeshi Hisamatsu, Yukihiro Nishio, Kimihiko Ito, Tadashi Kimura, Shoji Kamiura, Ken-ichirou Morishige

INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER　Vol. 25　No. 2　p. 288-295　2015/02　Research paper (scientific journal)

Usefulness of Duloxetine for Paclitaxel-Induced Peripheral Neuropathy Treatment in Gynecological Cancer Patients

Akiko Otake, Kiyoshi Yoshino, Yutaka Ueda, Kenjiro Sawada, Seiji Mabuchi, Toshihiro Kimura, Eiji Kobayashi, Aki Isobe, Tomomi Egawa-Takata, Shinya Matsuzaki, Masami Fujita, Tadashi Kimura

ANTICANCER RESEARCH　Vol. 35　No. 1　p. 359-363　2015/01　Research paper (scientific journal)

Efficacies and pregnant outcomes of fertility-sparing treatment with medroxyprogesterone acetate for endometrioid adenocarcinoma and complex atypical hyperplasia: our experience and a review of the literature

Chifumi Ohyagi-Hara, Kenjiro Sawada, Isobe Aki, Seiji Mabuchi, Eiji Kobayashi, Yutaka Ueda, Kiyoshi Yoshino, Masami Fujita, Tateki Tsutsui, Tadashi Kimura

ARCHIVES OF GYNECOLOGY AND OBSTETRICS　Vol. 291　No. 1　p. 151-157　2015/01　Research paper (scientific journal)

Clinical characteristics and outcomes of uterine tumors resembling ovarian sex-cord tumors (UTROSCT): a systematic review of literature

Erin A. Blake, Todd B. Sheridan, Karen L. Wang, Tsuyoshi Takiuchi, Michiko Kodama, Kenjiro Sawada, Koji Matsuo

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY　Vol. 181　p. 163-170　2014/10

Hypoxia-related microRNA, miR-199a-3p, inhibits ovarian cancer progression through the suppression of c-Met expression

Yasuto Kinose, Kenjiro Sawada, Koji Nakamura, Seiji Mabuchi, Ken-ichirou Morishige, Tadashi Kimura

CANCER RESEARCH　Vol. 74　No. 19　2014/10

Identification of microRNA which regulates paclitaxel resistance of ovarian cancer cells - a potential of miR-194 by attenuating paclitaxel resistance through the down-regulation of oncogene BMI-1

Koji Nakamura, Kenjiro Sawada, Yasuto Kinose, Kae Hashimoto, Seiji Mabuchi, Tadashi Kimura

CANCER RESEARCH　Vol. 74　No. 19　2014/10

TARGETING IKK beta SIGNALING PREVENTS PRETERM DELIVERY THROUGH INHIBITION OF INTERLEUKIN-6 PRODUCTION FROM AMNIOTIC MESENCHYMAL CELLS.

Aska Toda, Kenjiro Sawada, Tomoyuki Fujikawa, Kae Hashimoto, Ikuko Sawada, Yasuto Kinose, Akiko Itai, Tadashi Kimura

PLACENTA　Vol. 35　No. 10　p. A17-A18　2014/10

Perioperative Venous Thromboembolism in Patients with Gynecological Malignancies: A Lesson from Four Years of Recent Clinical Experience

Akiko Morimoto, Yutaka Ueda, Takeshi Yokoi, Yuki Tokizawa, Kiyoshi Yoshino, Masami Fujita, Toshihiro Kimura, Eiji Kobayashi, Shinya Matsuzaki, Tomomi Egawa-Takata, Kenjiro Sawada, Tateki Tsutsui, Tadashi Kimura

ANTICANCER RESEARCH　Vol. 34　No. 7　p. 3589-3595　2014/07　Research paper (scientific journal)

Uterine Cervical Cancer Displaying Tumor-Related Leukocytosis: A Distinct Clinical Entity With Radioresistant Feature

Seiji Mabuchi, Yuri Matsumoto, Mahiru Kawano, Kazumasa Minami, Yuji Seo, Tomoyuki Sasano, Ryoko Takahashi, Hiromasa Kuroda, Takeshi Hisamatsu, Aiko Kakigano, Masami Hayashi, Kenjiro Sawada, Toshimitsu Hamasaki, Eiichi Morii, Hirohisa Kurachi, Nariaki Matsuura, Tadashi Kimura

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE　Vol. 106　No. 7　2014/07　Research paper (scientific journal)

Combination Treatment With Trabectedin and Irinotecan or Topotecan Has Synergistic Effects Against Ovarian Clear Cell Carcinoma Cells

Mahiru Kawano, Seiji Mabuchi, Toshiko Kishimoto, Takeshi Hisamatsu, Yuri Matsumoto, Tomoyuki Sasano, Ryoko Takahashi, Kenjiro Sawada, Kazuhiro Takahashi, Toshifumi Takahashi, Toshimitsu Hamasaki, Tadashi Kimura

INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER　Vol. 24　No. 5　p. 829-837　2014/06　Research paper (scientific journal)

Targeting Inhibitor of NF-kappa b Kinase Beta (IKK beta) May Represent a Possible Novel Treatment for Endometriosis

Ikuko Sawada, Kae Hashimoto, Kenjiro Sawada, Tomoyuki Fujikawa, Akiko Itai, Tadashi Kimura

ENDOCRINE REVIEWS　Vol. 35　No. 3　2014/06

Targeting Ikk beta Signaling Prevents Preterm Delivery through the Inhibition of Interleukin-6 (IL-6) Production from Amniotic Mesenchymal Stromal Cells

Aska Toda, Kenjiro Sawada, Yasuto Kinose, Ikuko Sawada, Kae Hashimoto, Tomoyuki Fujikawa, Akiko Itai, Tadashi Kimura

ENDOCRINE REVIEWS　Vol. 35　No. 3　2014/06

The effect of raloxifene hydrochloride for the prevention of health care problems of patients who underwent surgeries for endometrial cancer: A multicenter clinical trial.

Koji Nakamura, Kenjiro Sawada, Michiyo Sugiyama, Seiji Mabuchi, Takeshi Hisamatsu, Yukihiro Nishio, Kimihiko Ito, Ken-ichirou Morishige, Tadashi Kimura, Shoji Kamiura

JOURNAL OF CLINICAL ONCOLOGY　Vol. 32　No. 15　2014/05

The Role of MicroRNAs in Ovarian Cancer

Yasuto Kinose, Kenjiro Sawada, Koji Nakamura, Tadashi Kimura

BIOMED RESEARCH INTERNATIONAL　Vol. 2014　2014

Targeting interleukin-6 receptor inhibits preterm delivery induced by inflammation

Atsuko Wakabayashi, Kenjiro Sawada, Masahiro Nakayama, Aska Toda, Akihito Kimoto, Seiji Mabuchi, Yasuto Kinose, Koji Nakamura, Kazuhiro Takahashi, Hirohisa Kurachi, Tadashi Kimura

MOLECULAR HUMAN REPRODUCTION　Vol. 19　No. 11　p. 718-726　2013/11　Research paper (scientific journal)

MACROPHAGES IN VILLOUS MESENCHYME PRODUCE INTERLEUKIN-6 IN RESPONSE TO INFECTION AND TARGETING INTERLEUKIN-6 SIGNALING INHIBITS PRETERM DELIVERY

Kenjiro Sawada

PLACENTA　Vol. 34　No. 10　p. A2-A3　2013/10

Potential Role of mTORC2 as a Therapeutic Target in Clear Cell Carcinoma of the Ovary

Takeshi Hisamatsu, Seiji Mabuchi, Yuri Matsumoto, Mahiru Kawano, Tomoyuki Sasano, Ryoko Takahashi, Kenjiro Sawada, Kimihiko Ito, Hirohisa Kurachi, Russell J. Schilder, Joseph R. Testa, Tadashi Kimura

MOLECULAR CANCER THERAPEUTICS　Vol. 12　No. 7　p. 1367-1377　2013/07　Research paper (scientific journal)

Phase I study of combination chemotherapy with irinotecan and gemcitabine for taxane/platinum resistant ovarian, fallopian tube, or primary peritoneal cancer

Kiyoshi Yoshino, Shoji Kamiura, Haruki Ogawa, Atsushi Tokuhira, Masahiko Takemura, Kenjiro Sawada, Yutaka Ueda, Seiji Mabuchi, Masami Fujita, Tateki Tsutsui, Tadashi Kimura

JOURNAL OF CLINICAL ONCOLOGY　Vol. 31　No. 15　2013/05

miR-92a Inhibits Peritoneal Dissemination of Ovarian Cancer Cells by Inhibiting Integrin alpha 5 Expression

Chifumi Ohyagi-Hara, Kenjiro Sawada, Shoji Kamiura, Yasuhiko Tomita, Aki Isobe, Kae Hashimoto, Yasuto Kinose, Seiji Mabuchi, Takeshi Hisamatsu, Toshifumi Takahashi, Keiichi Kumasawa, Shigenori Nagata, Ken-Ichirou Morishige, Ernst Lengyel, Hirohisa Kurachi, Tadashi Kimura

AMERICAN JOURNAL OF PATHOLOGY　Vol. 182　No. 5　p. 1876-1889　2013/05　Research paper (scientific journal)

A novel IKK beta inhibitor, IMD-0354, inhibits ovarian cancer dissemination by inhibiting VEGF production from cancer cells - the potential for a novel anti-angiogenic therapy

Yasuto Kinose, Kenjiro Sawada, Kae Hashimoto, Seiji Mabuchi, Ken-ichirou Morishige, Tadashi Kimura

CANCER RESEARCH　Vol. 73　No. 8　2013/04

Estradiol and raloxifene induce the proliferation of osteoblasts through G-protein-coupled receptor GPR30

H. Noda-Seino, K. Sawada, J. Hayakawa, C. Ohyagi-Hara, S. Mabuchi, K. Takahashi, Y. Nishio, M. Sakata, H. Kurachi, T. Kimura

Journal of Endocrinological Investigation　Vol. 36　No. 1　p. 21-27　2013/01　Research paper (scientific journal)

CD95 promotes tumour growth (vol 465, pg 492, 2010)

Lina Chen, Sun-Mi Park, Alexei V. Tumanov, Annika Hau, Kenjiro Sawada, Christine Feig, Jerrold R. Turner, Yang-Xin Fu, Iris L. Romero, Ernst Lengyel, Marcus E. Peter

NATURE　Vol. 491　No. 7426　2012/11

mTORC2 is a promising therapeutic target in epithelial ovarian cancer

Takeshi Hisamatsu, Seiji Mabuchi, Kae Hashimoto, Aki Isobe, Kenjiro Sawada, Tadashi Kimura

CANCER RESEARCH　Vol. 72　2012/04

Integrin beta 5 as a new target in ovarian cancer treatment

Chifumi Ohyagi, Kenjiro Sawada, Yasuto Kinose, Yasuhiko Tomita, Ken-ichirou Morishige, Shoji Kamiura, Tadashi Kimura

CANCER RESEARCH　Vol. 72　2012/04

Integrin inhibitors as a therapeutic agent for ovarian cancer.

Kenjiro Sawada, Chifumi Ohyagi-Hara, Tadashi Kimura, Ken-Ichirou Morishige

Journal of oncology　Vol. 2012　p. 915140-915140　2012　Research paper (scientific journal)

Balloon tamponade during cesarean section is useful for severe post-partum hemorrhage due to placenta previa

Takako Ishii, Kenjiro Sawada, Shunsuke Koyama, Aki Isobe, Atsuko Wakabayashi, Tsuyoshi Takiuchi, Takeshi Kanagawa, Takuji Tomimatsu, Kazuhide Ogita, Tadashi Kimura

JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH　Vol. 38　No. 1　p. 102-107　2012/01　Research paper (scientific journal)

The expression of inflammatory cytokines in chorioamnionitis (CAM) placenta and the potential as a therapeutic target

Atsuko Wakabayashi, Kenjiro Sawada, Masahiro Sakata, Akihito Kimoto, Masahiro Nakayama, Tadashi Kimura

PLACENTA　Vol. 32　No. 9　p. A170-A170　2011/09

CD95 promotes tumour growth (vol 465, pg 492, 2010)

Lina Chen, Sun-Mi Park, Alexei V. Tumanov, Annika Hau, Kenjiro Sawada, Christine Feig, Jerrold R. Turner, Yang-Xin Fu, Iris L. Romero, Ernst Lengyel, Marcus E. Peter

NATURE　Vol. 475　No. 7355　2011/07

The Activity of Trabectedin As a Single Agent or in Combination with Everolimus for Clear Cell Carcinoma of the Ovary

Seiji Mabuchi, Takeshi Hisamatsu, Chiaki Kawase, Masami Hayashi, Kenjiro Sawada, Kazuya Mimura, Kazuhiro Takahashi, Toshifumi Takahashi, Hirohisa Kurachi, Tadashi Kimura

CLINICAL CANCER RESEARCH　Vol. 17　No. 13　p. 4462-4473　2011/07　Research paper (scientific journal)

Foretinib (GSK1363089), an Orally Available Multikinase Inhibitor of c-Met and VEGFR-2, Blocks Proliferation, Induces Anoikis, and Impairs Ovarian Cancer Metastasis

Marion Zillhardt, Sun-Mi Park, Iris L. Romero, Kenjiro Sawada, Anthony Montag, Thomas Krausz, S. Diane Yamada, Marcus E. Peter, Ernst Lengyel

CLINICAL CANCER RESEARCH　Vol. 17　No. 12　p. 4042-4051　2011/06　Research paper (scientific journal)

Analysis of functional role of interleukin-6 secreted by tumor-associated macrophages in ovarian cancer ascites

Aki Isobe, Kenjiro Sawada, Chifumi Ooyagi, Seiji Mabuchi, Atsuko Wakabayashi, Ken-ichirou Morishig, Tadashi Kimura

CANCER RESEARCH　Vol. 71　2011/04

Identification of microRNA which regulates peritoneal dissemination of ovarian cancer

Chifumi Ohyagi, Kenjiro Sawada, Ken-ichiro Morishige, Ernst Lengyel, Tadashi Kimura

CANCER RESEARCH　Vol. 71　2011/04

CD95 promotes tumour growth (vol 465, pg 492, 2010)

Lina Chen, Sun-Mi Park, Alexei V. Tumanov, Annika Hau, Kenjiro Sawada, Christine Feig, Jerrold R. Turner, Yang-Xin Fu, Iris L. Romero, Ernst Lengyel, Marcus E. Peter

NATURE　Vol. 471　No. 7337　2011/03

Pseudomyxoma peritonei originating from colorectal cancer during pregnancy

Shinsuke Koyama, Takuji Tomimatsu, Kenjiro Sawada, Takeshi Kanagawa, Tateki Tsutsui, Tadashi Kimura

JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH　Vol. 37　No. 3　p. 254-258　2011/03　Research paper (scientific journal)

A novel, ligand independent activation of c-Met by alpha 5 beta 1-integrin regulates ovarian cancer invasion and metastasis

Anirban K. Mitra, Kenjiro Sawada, Payal Tiwari, Keeley Mui, Katja Gwin

CLINICAL & EXPERIMENTAL METASTASIS　Vol. 28　No. 2　p. 181-181　2011/02

Vascular Endothelial Growth Factor Is a Promising Therapeutic Target for the Treatment of Clear Cell Carcinoma of the Ovary

Seiji Mabuchi, Chiaki Kawase, Deborah A. Altomare, Kenichirou Morishige, Masami Hayashi, Kenjiro Sawada, Kimihiko Ito, Yoshito Terai, Yukihiro Nishio, Andres J. Klein-Szanto, Robert A. Burger, Masahide Ohmichi, Joseph R. Testa, Tadashi Kimura

MOLECULAR CANCER THERAPEUTICS　Vol. 9　No. 8　p. 2411-2422　2010/08　Research paper (scientific journal)

[Follicle stimulating hormone (FSH)].

Kenjiro Sawada, Tadashi Kimura, Ken-ichirou Morishige

Nihon rinsho. Japanese journal of clinical medicine　Vol. 68 Suppl 7　p. 220-2　2010/07　Research paper (scientific journal)

CD95 promotes tumour growth

Lina Chen, Sun-Mi Park, Alexei V. Tumanov, Annika Hau, Kenjiro Sawada, Christine Feig, Jerrold R. Turner, Yang-Xin Fu, Iris L. Romero, Ernst Lengyel, Marcus E. Peter

NATURE　Vol. 465　No. 7297　p. 492-496　2010/05　Research paper (scientific journal)

Prenatal diagnosis of fetal intracranial hemorrhage in pregnancy complicated by idiopathic thrombocytopenic purpura

Shinsuke Koyama, Takuji Tomimatsu, Kenjiro Sawada, Takeshi Kanagawa, Aki Isobe, Yukiko Taniguchi, Tomo Wada, Tadashi Kimura, Hitomi Arahori, Yasuji Kitabatake, Kazuko Wada

PRENATAL DIAGNOSIS　Vol. 30　No. 5　p. 489-491　2010/05

CD95/-AS promotes tumorigenesis

Lina Chen, Sun-Mi Park, Alexei V. Tumanov, Annika Hau, Kenjiro Sawada, Christine Feig, Jerrold R. Turner, Yang-Xin Fu, Iris Romero, Ernst Lengyel, Marcus E. Peter

CANCER RESEARCH　Vol. 70　2010/04

Cervical insufficiency following cesarean delivery after prolonged second stage of labor: Experiences of two cases

Shinsuke Koyama, Takuji Tomimatsu, Takeshi Kanagawa, Kenjiro Sawada, Tateki Tsutsui, Tadashi Kimura

JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH　Vol. 36　No. 2　p. 411-413　2010/04　Research paper (scientific journal)

A Case of Complete Hydatidiform Mole with Coexistent Fetus: Conclusive Diagnosis of Androgenesis of the Molar Placenta by Variation of Paternal Acrocentric Short Arms

Shinsuke Koyama, Takuji Tomimatsu, Kenjiro Sawada, Takeshi Kanagawa, Aki Isobe, Yukiko Kinugasa, Tateki Tsutsui, Tadashi Kimura

AMERICAN JOURNAL OF PERINATOLOGY　Vol. 27　No. 2　p. 143-149　2010/02　Research paper (scientific journal)

Fasudil Inhibits Lysophosphatidic Acid-Induced Invasiveness of Human Ovarian Cancer Cells

Seiji Ogata, Ken-Ichirou Morishige, Kenjiro Sawada, Kae Hashimoto, Seiji Mabuchi, Chiaki Kawase, Chifumi Ooyagi, Masahiro Sakata, Tadashi Kimura

INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER　Vol. 19　No. 9　p. 1473-1480　2009/12　Research paper (scientific journal)

Up-Regulation of alpha(5)-Integrin by E-Cadherin Loss in Hypoxia and Its Key Role in the Migration of Extravillous Trophoblast Cells during Early Implantation

Emi Arimoto-Ishida, Masahiro Sakata, Kenjiro Sawada, Masahiro Nakayama, Fumihito Nishimoto, Seiji Mabuchi, Takashi Takeda, Toshiya Yamamoto, Aki Isobe, Yoko Okamoto, Ernst Lengyel, Noriyuki Suehara, Ken-ichirou Morishige, Tadashi Kimura

ENDOCRINOLOGY　Vol. 150　No. 9　p. 4306-4315　2009/09　Research paper (scientific journal)

mTOR Is a Promising Therapeutic Target Both in Cisplatin-Sensitive and Cisplatin-Resistant Clear Cell Carcinoma of the Ovary

Seiji Mabuchi, Chiaki Kawase, Deborah A. Altomare, Kenichirou Morishige, Kenjiro Sawada, Masami Hayashi, Masahiko Tsujimoto, Mareo Yamoto, Andres J. Klein-Szanto, Russell J. Schilder, Masahide Ohmichi, Joseph R. Testa, Tadashi Kimura

CLINICAL CANCER RESEARCH　Vol. 15　No. 17　p. 5404-5413　2009/09　Research paper (scientific journal)

Metal Transcription Factor-1 Is Involved in Hypoxia-Dependent Regulation of Placenta Growth Factor in Trophoblast-Derived Cells

Fumihito Nishimoto, Masahiro Sakata, Ryoko Minekawa, Yoko Okamoto, Asako Miyake, Aki Isobe, Toshiya Yamamoto, Takashi Takeda, Emi Ishida, Kenjiro Sawada, Ken-ichiro Morishige, Tadashi Kimura

ENDOCRINOLOGY　Vol. 150　No. 4　p. 1801-1808　2009/04　Research paper (scientific journal)

Peripheral quantitative computed tomography is useful to monitor response to alendronate therapy in postmenopausal women

Kenjiro Sawada, Ken-ichirou Morishige, Yukihiro Nishio, Jun Hayakawa, Seiji Mabuchi, Aki Isobe, Seiji Ogata, Masahiro Sakata, Masahide Ohmichi, Tadashi Kimura

JOURNAL OF BONE AND MINERAL METABOLISM　Vol. 27　No. 2　p. 175-181　2009/03　Research paper (scientific journal)

Loss of E-cadherin promotes ovarian cancer metastasis via alpha(5)-integrin, which is a therapeutic target

Kenjiro Sawada, Anirban K. Mitra, A. Reza Radjabi, Vinay Bhaskar, Emily O. Kistner, Maria Tretiakova, Sujatha Jagadeeswaran, Anthony Montag, Amy Becker, Hilary A. Kenny, Marcus E. Peter, Vanitha Ramakrishnan, S. Diane Yamada, Ernst Lengyel

CANCER RESEARCH　Vol. 68　No. 7　p. 2329-2339　2008/04　Research paper (scientific journal)

Thrombin induces tumor invasion through the induction and association of matrix metalloproteinase-9 and beta 1-integrin on the cell surface

A. Reza Radjabi, Kenjiro Sawada, Sujatha Jagadeeswaran, Alfred Eichbichler, Hilary A. Kenny, Anthony Montag, Katharina Bruno, Ernst Lengyel

JOURNAL OF BIOLOGICAL CHEMISTRY　Vol. 283　No. 5　p. 2822-2834　2008/02　Research paper (scientific journal)

In vitro and in vivo assays to analyze the contribution of Rho kinase in angiogenesis

Kenjiro Sawada, Ken-ichirou Morishige, Seiji Mabuchi, Seiji Ogata, Chiaki Kawase, Masahiro Sakata, Tadashi Kimura

SMALL GTPASES IN DISEASE, PT B　Vol. 439　p. 395-412　2008　Part of collection (book)

Geranylgeranylacetone inhibits ovarian cancer progression in vitro and in vivo

Kae Hashimoto, Ken-ichirou Morishige, Kenjiro Sawada, Seiji Ogata, Masahiro Tahara, Shoko Shimizu, Masahiro Sakata, Keiichi Tasaka, Tadashi Kimura

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS　Vol. 356　No. 1　p. 72-77　2007/04　Research paper (scientific journal)

Peripheral quantitative computed tomography (pQCT) is useful for monitoring bone mineral density of the patients who receive hormone replacement therapy

Kenjiro Sawada, Ken-Ichirou Morishige, Masahide Ohmichi, Yukihiro Nishio, Toshiya Yamamoto, Jun Hayakawa, Seiji Mabuchi, Aki Isobe, Hiroshi Sasaki, Masahiro Sakata, Keiichi Tasaka, Yuji Murata

MATURITAS　Vol. 56　No. 4　p. 343-349　2007/04　Research paper (scientific journal)

Alendronate suppresses tumor angiogenesis by inhibiting Rho activation of endothelial cells

Kae Hashimoto, Ken-ichirou Morishige, Kenjiro Sawada, Masahiro Tahara, Shoko Shimizu, Seiji Ogata, Masahiro Sakata, Keiichi Tasaka, Tadashi Kimura

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS　Vol. 354　No. 2　p. 478-484　2007/03　Research paper (scientific journal)

Tyrosine kinase mutations in human cancer

Ernst Lengyel, Kenjiro Sawada, Ravi Salgia

CURRENT MOLECULAR MEDICINE　Vol. 7　No. 1　p. 77-84　2007/02

c-Met overexpression is a prognostic factor in ovarian cancer and an effective target for inhibition of peritoneal dissemination and invasion

Kenjiro Sawada, A. Reza Radjabi, Nariyoshi Shinomiya, Emily Kistner, Hilary Kenny, Amy R. Becker, Muge A. Turkyilmaz, Ravi Salgia, S. Diane Yamada, George F. Vande Woude, Maria S. Tretiakova, Ernst Lengyel

CANCER RESEARCH　Vol. 67　No. 4　p. 1670-1679　2007/02　Research paper (scientific journal)

Down-regulation of the receptor tyrosine kinase c-Met inhibits invasion and adhesion of ovarian cancer cells

Kenjiro Sawada, A. Reza Radjabi, George Vande Woude, Nariyoshi Shinomiya, Seiko Diane Yamada, Ernst Lengyel

CANCER RESEARCH　Vol. 66　No. 8　2006/04

Gestational change of K+ channel opener effect is correlated with the expression of uterine KATP channel subunits.

Kenjiro Sawada, Ken-ichirou Morishige, Kae Hashimoto, Keiichi Tasaka, Hirohisa Kurachi, Yuji Murata, Yoshihisa Kurachi

European journal of obstetrics, gynecology, and reproductive biology　Vol. 122　No. 1　p. 49-56　2005/09/01　Research paper (scientific journal)

Geranylgeranylacetone inhibits lysophosphatidic acid-induced invasion of human ovarian carcinoma cells in vitro.

Kae Hashimoto, Ken-ichirou Morishige, Kenjiro Sawada, Masahiro Tahara, Shoko Shimizu, Masahiro Sakata, Keiichi Tasaka, Yuji Murata

Cancer　Vol. 103　No. 7　p. 1529-36　2005/04/01　Research paper (scientific journal)

Alendronate inhibits intraperitoneal dissemination in in vivo ovarian cancer model.

Kae Hashimoto, Ken-Ichirou Morishige, Kenjiro Sawada, Masahiro Tahara, Rikako Kawagishi, Yoshihide Ikebuchi, Masahiro Sakata, Keiichi Tasaka, Yuji Murata

Cancer research　Vol. 65　No. 2　p. 540-5　2005/01/15　Research paper (scientific journal)

Induction of glucose transporter 1 expression through hypoxia-inducible factor 1alpha under hypoxic conditions in trophoblast-derived cells.

Masami Hayashi, Masahiro Sakata, Takashi Takeda, Toshiya Yamamoto, Yoko Okamoto, Kenjiro Sawada, Akiko Kimura, Ryoko Minekawa, Masahiro Tahara, Keiichi Tasaka, Yuji Murata

The Journal of endocrinology　Vol. 183　No. 1　p. 145-54　2004/10　Research paper (scientific journal)

Rapid changes of flow-mediated dilatation after surgical menopause

Masahide Ohmichi, Yuki Kanda, Koji Hisamoto, Ken-ichiro Morishige, Kazuhiro Takahashi, Kenjiro Sawada, Ryoko Minekawa, Keiichi Tasaka, Yuji Murata

Maturitas　Vol. 44　No. 2　p. 125-131　2003/02/25　Research paper (scientific journal)

Etidronate and hormone replacement therapy (HRT) for postmenopausal women with osteoporosis despite HRT

Ken-Ichirou Morishige, Toshiya Yamamoto, Kenjiro Sawada, Masahide Ohmichi, Keiichi Tasaka, Yuji Murata

Archives of Gynecology and Obstetrics　Vol. 268　No. 2　p. 105-106　2003　Research paper (scientific journal)