Mice lacking PLAP-1/asporin counteracts high fat diet-induced metabolic disorder and alveolar bone loss by controlling adipose tissue expansion.

Hiromi Sakashita, Satoru Yamada, Masaki Kinoshita, Tetsuhiro Kajikawa, Tomoaki Iwayama, Shinya Murakami

Scientific reports　Vol. 11　No. 1　p. 4970-4970　2021/03/02　Research paper (scientific journal)

Nanoscale observation of PM2.5 incorporated into mammalian cells using scanning electron-assisted dielectric microscope.

Tomoko Okada, Tomoaki Iwayama, Shinya Murakami, Masaki Torimura, Toshihiko Ogura

Scientific reports　Vol. 11　No. 1　p. 228-228　2021/01/08　Research paper (scientific journal)

Osteoblastic lysosome plays a central role in mineralization.

Tomoaki Iwayama, Tomoko Okada, Tsugumi Ueda, Kiwako Tomita, Shuji Matsumoto, Masahide Takedachi, Satoshi Wakisaka, Takeshi Noda, Taku Ogura, Tomomichi Okano, Peter Fratzl, Toshihiko Ogura, Shinya Murakami

Science advances　Vol. 5　No. 7　2019/07

PDGFRα signaling drives adipose tissue fibrosis by targeting progenitor cell plasticity.

Tomoaki Iwayama, Cameron Steele, Longbiao Yao, Mikhail G Dozmorov, Dimitris Karamichos, Jonathan D Wren, Lorin E Olson

Genes & development　Vol. 29　No. 11　p. 1106-19　2015/06/01

Involvement of PDGF in fibrosis and scleroderma: recent insights from animal models and potential therapeutic opportunities.

Tomoaki Iwayama, Lorin E Olson

Current rheumatology reports　Vol. 15　No. 2　p. 304-304　2013/02

Adiponectin regulates functions of gingival fibroblasts and periodontal ligament cells.

T Iwayama, M Yanagita, K Mori, K Sawada, M Ozasa, M Kubota, K Miki, Y Kojima, M Takedachi, M Kitamura, Y Shimabukuro, T Hashikawa, S Murakami

Journal of periodontal research　Vol. 47　No. 5　p. 563-71　2012/10

Anti-inflammatory Annexin A1 in Periodontitis via Formyl Peptide Receptor 2.

M Takedachi, M Murata, K Sawada, K Kawasaki, K Kawakami, A Sugimoto, C Morimoto, H Sakashita, Y Usami, C Fujihara, T Iwayama, S Murakami

Journal of dental research　Vol. 104　No. 9　p. 1014-1021　2025/08　Research paper (scientific journal)

Mice Lacking PLAP-1/Asporin Show Alteration of Periodontal Ligament Structures and Acceleration of Bone Loss in Periodontitis.

Masaki Kinoshita, Satoru Yamada, Junichi Sasaki, Shigeki Suzuki, Tetsuhiro Kajikawa, Tomoaki Iwayama, Chiharu Fujihara, Satoshi Imazato, Shinya Murakami

International journal of molecular sciences　Vol. 24　No. 21　2023/11/05　Research paper (scientific journal)

Activation of periodontal ligament cell cytodifferentiation by juxtacrine signaling from cementoblasts.

Keigo Sawada, Junpei Shimomura, Masahide Takedachi, Mari Murata, Chiaki Morimoto, Kohsuke Kawasaki, Kazuma Kawakami, Tomoaki Iwayama, Shinya Murakami

Journal of periodontology　2023/07/26　Research paper (scientific journal)

Periodontal Tissue Regeneration by Transplantation of Autologous Adipose Tissue-Derived Multi-Lineage Progenitor Cells With Carbonate Apatite.

Masahide Takedachi, Kohsuke Kawasaki, Keigo Sawada, Kazuma Sakura, Mari Murata, Junpei Shimomura, Kazuma Kawakami, Chiaki Morimoto, Koji Miki, Noboru Takeshita, Tomoaki Iwayama, Hanayuki Okura, Akifumi Matsuyama, Masahiro Saito, Masahiro Kitamura, Shinya Murakami

Cell transplantation　Vol. 32　p. 9636897231198296-9636897231198296　2023　Research paper (scientific journal)

Evaluation of periodontitis-related tooth loss according to the new 2018 classification of periodontitis.

Masahide Takedachi, Yoshio Shimabukuro, Keigo Sawada, Mami Koshimizu, Kazuko Shinada, Harumi Asai, Ayumi Mizoguchi, Yuko Hayashi, Akina Tsukamoto, Midori Miyago, Fuuka Nishihara, Takako Nishihata, Michiyo Shimabukuro, Hiroyuki Kurakami, Tomoharu Sato, Yayoi Hamazaki, Tomoaki Iwayama, Chiharu Fujihara, Shinya Murakami

Scientific reports　Vol. 12　No. 1　p. 11893-11893　2022/07/13　Research paper (scientific journal)

Periodontal tissue regeneration by transplantation of autologous adipose tissue-derived multi-lineage progenitor cells.

Masahide Takedachi, Keigo Sawada, Kazuma Sakura, Chiaki Morimoto, Asae Hirai, Tomoaki Iwayama, Junpei Shimomura, Kohsuke Kawasaki, Chiharu Fujihara, Yoichiro Kashiwagi, Akimitsu Miyake, Tomomi Yamada, Hanayuki Okura, Akifumi Matsuyama, Masahiro Saito, Masahiro Kitamura, Shinya Murakami

Scientific reports　Vol. 12　No. 1　p. 8126-8126　2022/05/17　Research paper (scientific journal)

Reciprocal role of PLAP-1 in HIF-1α-mediated responses to hypoxia.

Masahide Takedachi, Satomi Yamamoto, Kohsuke Kawasaki, Junpei Shimomura, Mari Murata, Chiaki Morimoto, Asae Hirai, Kazuma Kawakami, Phan Bhongsatiern, Tomoaki Iwayama, Keigo Sawada, Satoru Yamada, Shinya Murakami

Journal of periodontal research　2022/02/09　Research paper (scientific journal)

Periodontal inflamed surface area is associated with hs-CRP in septuagenarian Japanese adults in cross-sectional findings from the SONIC study.

Koji Miki, Masahiro Kitamura, Kodai Hatta, Kei Kamide, Yasuyuki Gondo, Motozo Yamashita, Masahide Takedachi, Takenori Nozaki, Chiharu Fujihara, Yoichiro Kashiwagi, Tomoaki Iwayama, Toshihito Takahashi, Hitomi Sato, Yuki Murotani, Mai Kabayama, Yasushi Takeya, Yoichi Takami, Hiroshi Akasaka, Koichi Yamamoto, Ken Sugimoto, Tatsuro Ishizaki, Yukie Masui, Hiromi Rakugi, Kazunori Ikebe, Shinya Murakami

Scientific reports　Vol. 11　No. 1　p. 14436-14436　2021/07/14　Research paper (scientific journal)

Hypoxia stimulates collagen hydroxylation in gingival fibroblasts and periodontal ligament cells.

Chiaki Morimoto, Masahide Takedachi, Kohsuke Kawasaki, Junpei Shimomura, Mari Murata, Asae Hirai, Kazuma Kawakami, Keigo Sawada, Tomoaki Iwayama, Shinya Murakami

Journal of periodontology　2021/03/04　Research paper (scientific journal)

Association of periodontal disease with atherosclerosis in 70-year-old Japanese older adults.

Masahiro Kitamura, Kazunori Ikebe, Kei Kamide, Yasuyuki Gondo, Motozo Yamashita, Masahide Takedachi, Takenori Nozaki, Chiharu Fujihara, Satoru Yamada, Yoichiro Kashiwagi, Koji Miki, Tomoaki Iwayama, Kodai Hatta, Yusuke Mihara, Yuko Kurushima, Hajime Takeshita, Mai Kabayama, Ryousuke Oguro, Tatsuo Kawai, Hiroshi Akasaka, Yasushi Takeya, Koichi Yamamoto, Ken Sugimoto, Tatsuro Ishizaki, Yasumichi Arai, Yukie Masui, Ryutaro Takahashi, Hiromi Rakugi, Yoshinobu Maeda, Shinya Murakami

Odontology　2020/11/04　Research paper (scientific journal)

Trophic factors from adipose tissue-derived multi-lineage progenitor cells promote cytodifferentiation of periodontal ligament cells.

Keigo Sawada, Masahide Takedachi, Satomi Yamamoto, Chiaki Morimoto, Masao Ozasa, Tomoaki Iwayama, Chun Man Lee, Hanayuki Okura, Akifumi Matsuyama, Masahiro Kitamura, Shinya Murakami

Biochemical and biophysical research communications　Vol. 464　No. 1　p. 299-305　2015/08/14

Detrimental effects of duplicate reads and low complexity regions on RNA- and ChIP-seq data.

Mikhail G Dozmorov, Indra Adrianto, Cory B Giles, Edmund Glass, Stuart B Glenn, Courtney Montgomery, Kathy L Sivils, Lorin E Olson, Tomoaki Iwayama, Willard M Freeman, Christopher J Lessard, Jonathan D Wren

BMC bioinformatics　Vol. 16 Suppl 13　2015

Periodontal tissue regeneration by transplantation of adipose tissue-derived multi-lineage progenitor cells

OZASA MASAO, SAWADA KEIGO, IWAYAMA TOMOAKI, YAMAMOTO SATOMI, MORIMOTO CHIAKI, OKURA HANAYUKI, MATSUYAMA AKIHUMI, KOMODA HIROSHI, LEE CHUN MAN, SAWA YOSHIKI, KITAMURA MASAHIRO, HASHIKAWA TOMOKO, TAKEDACHI MASAHIDE, MURAKAMI SHINYA

Inflamm Regen (Web)　Vol. 34　No. 2　2014

Fibroblast growth factor-2 stimulates directed migration of periodontal ligament cells via PI3K/AKT signaling and CD44/hyaluronan interaction.

Yoshio Shimabukuro, Hiroaki Terashima, Masahide Takedachi, Kenichiro Maeda, Tomomi Nakamura, Keigo Sawada, Mariko Kobashi, Toshihito Awata, Hiroyuki Oohara, Takanobu Kawahara, Tomoaki Iwayama, Tomoko Hashikawa, Manabu Yanagita, Satoru Yamada, Shinya Murakami

Journal of cellular physiology　Vol. 226　No. 3　p. 809-21　2011/03

Reduction of N-glycolylneuraminic acid xenoantigen on human adipose tissue-derived stromal cells/mesenchymal stem cells leads to safer and more useful cell sources for various stem cell therapies.

Hiroshi Komoda, Hanayuki Okura, Chun Man Lee, Nagako Sougawa, Tomoaki Iwayama, Tomoko Hashikawa, Ayami Saga, Aya Yamamoto-Kakuta, Akihiro Ichinose, Shinya Murakami, Yoshiki Sawa, Akifumi Matsuyama

Tissue engineering. Part A　Vol. 16　No. 4　p. 1143-55　2010/04

Basic fibroblast growth factor regulates expression of heparan sulfate in human periodontal ligament cells.

Yoshio Shimabukuro, Tomoo Ichikawa, Yoshimitsu Terashima, Tomoaki Iwayama, Hiroyuki Oohara, Tetsuhiro Kajikawa, Ryohei Kobayashi, Hiroaki Terashima, Masahide Takedachi, Mami Terakura, Tomoko Hashikawa, Satoru Yamada, Shinya Murakami

Matrix biology : journal of the International Society for Matrix Biology　Vol. 27　No. 3　p. 232-41　2008/04