顔写真

PHOTO

Kazuhiro Takuma
田熊 一敞
Kazuhiro Takuma
田熊 一敞
Institutional repository
Graduate School of Dentistry　Course for Oral Sciences，Professor
Institutional repository

Research History 8

  1. 2015/04 - Present
    大阪大学大学院　連合小児発達学研究科　教授 (兼任)

  2. 2014/07 - Present
    大阪大学大学院　薬学研究科　教授 (兼任)

  3. 2014/07 - Present
    大阪大学大学院　歯学研究科　教授

  4. 2008/04 - 2014/07
    Osaka University　Graduate School of Pharmaceutical Sciences

  5. 2007/04 - 2008/03
    Kanazawa University　Graduate School of Natural Science and Technology

  6. 2004/04 - 2007/03
    Kanazawa University　Graduate School of Natural Science and Technology

  7. 1996/04 - 2004/03
    Kobe Gakuin University　The Faculty of Pharmaceutical Sciences

  8. 2001/10 - 2002/09
    米国コロンビア大学 医学部　博士研究員

Education 3

  1. Osaka University

    - 1996

  2. Osaka University

    - 1993

  3. Osaka University　School of Pharmaceutical Sciences

    - 1991

Committee Memberships 1

  1. The Japanese Pharmacological Society　Councilor　Academic society

    2001 -

Professional Memberships 15

  1. Japanese Association for Oral Biology

  2. 国際神経化学会

  3. 米国神経科学学会

  4. 日本神経精神薬理学会

  5. 日本神経科学学会

  6. 日本神経化学会

  7. 日本薬学会

  8. 日本薬理学会

  9. International Society for Neurochemistry

  10. Society for Neuroscience

  11. Japanese Society of Neuropsychopharmacology

  12. Japan Neuroscience Society

  13. The Japanese Society for Neurochemistry

  14. The Pharmaceutical Society of Japan

  15. The Japanese Pharmacological Society

Research Areas 2

  1. Life sciences / Pharmaceuticals - health and biochemistry /

  2. Life sciences / Neuroscience - general /

Awards 3

  1. Young Scientist Award of The Japanese Pharmacological Society

    2006

  2. The Award for Young Investigator of Japanese Society for Neurochemistry

    2006

  3. The Pharmaceutical Society of Japan Kinki Division Encouragement Award

    2001

Papers 153

  1. Brain region–specific neural activation by low-dose opioid promotes social behavior

    Soichiro Ohnami, Megumi Naito, Haruki Kawase, Momoko Higuchi, Shigeru Hasebe, Keiko Takasu, Ryo Kanemaru, Yuki Azuma, Rei Yokoyama, Takahiro Kochi, Eiji Imado, Takeru Tahara, Yaichiro Kotake, Satoshi Asano, Naoya Oishi, Kazuhiro Takuma, Hitoshi Hashimoto, Koichi Ogawa, Atsushi Nakamura, Hidekuni Yamakawa, Yukio Ago

    JCI Insight　Vol. 9　No. 23　2024/12/06　Research paper (scientific journal)

    Publisher: American Society for Clinical Investigation

  2. 胎生期PGD2-DP1シグナル活性化はマウスの自閉症様の精神行動異常を引き起こす

    村田 拳一朗, 早田 敦子, 菊池 泰河, 岩橋 美咲, 毛利 育子, 橘 雅弥, 田熊 一敞, 片山 泰一, 谷池 雅子, 橋本 均

    日本脳科学会プログラム・抄録集　Vol. 50回　p. np18-np18　2023/12

    Publisher: 日本脳科学会

  3. Pituitary Adenylate Cyclase-Activating Polypeptide deficient mice show length abnormalities of the axon initial segment

    Misaki Iwahashi, Takeshi Yoshimura, Wakana Harigai, Kazuhiro Takuma, Hitoshi Hashimoto, Taiichi Katayama, Atsuko Hayata-Takano

    Journal of Pharmacological Sciences　2023/08　Research paper (scientific journal)

    Publisher: Elsevier BV

  4. Prenatal exposure to valproic acid causes allodynia associated with spinal microglial activation

    Eiji Imado, Samnang Sun, Abrar Rizal Abawa, Takeru Tahara, Takahiro Kochi, Tran Ngoc Bao Huynh, Satoshi Asano, Shigeru Hasebe, Yoki Nakamura, Kazue Hisaoka-Nakashima, Yaichiro Kotake, Masahiro Irifune, Kazuhiro Tsuga, Kazuhiro Takuma, Norimitsu Morioka, Norikazu Kiguchi, Yukio Ago

    Neurochemistry International　Vol. 160　p. 105415-105415　2022/11　Research paper (scientific journal)

    Publisher: Elsevier BV

  5. Small-molecule non-peptide antagonists of the PACAP receptor attenuate acute restraint stress-induced anxiety-like behaviors in mice.

    Yusuke Shintani, Yui Yamano, Manato Kuta, Rei Takeshita, Kazuhiro Takuma, Takuya Okada, Naoki Toyooka, Ichiro Takasaki, Atsuro Miyata, Takashi Kurihara, Hitoshi Hashimoto, Atsuko Hayata-Takano

    Biochemical and biophysical research communications　Vol. 631　p. 146-151　2022/09/26　Research paper (scientific journal)

  6. Oxytocin ameliorates impaired social behavior in a mouse model of 3q29 deletion syndrome.

    Tomoya Takemoto, Masayuki Baba, Kazumasa Yokoyama, Kohei Kitagawa, Kazuki Nagayasu, Yukio Ago, Kaoru Seiriki, Atsuko Hayata-Takano, Atsushi Kasai, Daisuke Mori, Norio Ozaki, Kazuhiro Takuma, Ryota Hashimoto, Hitoshi Hashimoto, Takanobu Nakazawa

    Molecular Brain　Vol. 15　No. 1　p. 26-26　2022/03/28　Research paper (scientific journal)

  7. Multiple alterations in glutamatergic transmission and dopamine D2 receptor splicing in induced pluripotent stem cell-derived neurons from patients with familial schizophrenia.

    Kana Yamamoto, Toshihiko Kuriu, Kensuke Matsumura, Kazuki Nagayasu, Yoshinori Tsurusaki, Noriko Miyake, Hidenaga Yamamori, Yuka Yasuda, Michiko Fujimoto, Mikiya Fujiwara, Masayuki Baba, Kohei Kitagawa, Tomoya Takemoto, Nanaka Gotoda-Nishimura, Tomohiro Takada, Kaoru Seiriki, Atsuko Hayata-Takano, Atsushi Kasai, Yukio Ago, Satoshi Kida, Kazuhiro Takuma, Fumihito Ono, Naomichi Matsumoto, Ryota Hashimoto, Hitoshi Hashimoto, Takanobu Nakazawa

    Translational psychiatry　Vol. 11　No. 1　p. 548-548　2021/10/25　Research paper (scientific journal)

  8. Intranasal oxytocin administration ameliorates social behavioral deficits in a POGZWT/Q1038R mouse model of autism spectrum disorder.

    Kohei Kitagawa, Kensuke Matsumura, Masayuki Baba, Momoka Kondo, Tomoya Takemoto, Kazuki Nagayasu, Yukio Ago, Kaoru Seiriki, Atsuko Hayata-Takano, Atsushi Kasai, Kazuhiro Takuma, Ryota Hashimoto, Hitoshi Hashimoto, Takanobu Nakazawa

    Molecular brain　Vol. 14　No. 1　p. 56-56　2021/03/16　Research paper (scientific journal)

  9. Lipocalin-type prostaglandin D synthase regulates light-induced phase advance of the central circadian rhythm in mice

    Chihiro Kawaguchi, Norihito Shintani, Atsuko Hayata-Takano, Michiyoshi Hatanaka, Ai Kuromi, Reiko Nakamura, Yui Yamano, Yusuke Shintani, Katsuya Nagai, Soken Tsuchiya, Yukihiko Sugimoto, Atsushi Ichikawa, Yasushi Okuno, Yoshihiro Urade, Hiroyuki Hirai, Kin-ya Nagata, Masataka Nakamura, Shuh Narumiya, Takanobu Nakazawa, Atsushi Kasai, Yukio Ago, Kazuhiro Takuma, Akemichi Baba, Hitoshi Hashimoto

    Communications Biology　Vol. 3　No. 1　2020/12　Research paper (scientific journal)

    Publisher: Springer Science and Business Media LLC

  10. Pathogenic POGZ mutation causes impaired cortical development and reversible autism-like phenotypes.

    Kensuke Matsumura, Kaoru Seiriki, Shota Okada, Masashi Nagase, Shinya Ayabe, Ikuko Yamada, Tamio Furuse, Hirotoshi Shibuya, Yuka Yasuda, Hidenaga Yamamori, Michiko Fujimoto, Kazuki Nagayasu, Kana Yamamoto, Kohei Kitagawa, Hiroki Miura, Nanaka Gotoda-Nishimura, Hisato Igarashi, Misuzu Hayashida, Masayuki Baba, Momoka Kondo, Shigeru Hasebe, Kosei Ueshima, Atsushi Kasai, Yukio Ago, Atsuko Hayata-Takano, Norihito Shintani, Tokuichi Iguchi, Makoto Sato, Shun Yamaguchi, Masaru Tamura, Shigeharu Wakana, Atsushi Yoshiki, Ayako M Watabe, Hideyuki Okano, Kazuhiro Takuma, Ryota Hashimoto, Hitoshi Hashimoto, Takanobu Nakazawa

    Nature communications　Vol. 11　No. 1　p. 859-859　2020/02/26　Research paper (scientific journal)

  11. Activation of the VPAC2 Receptor Impairs Axon Outgrowth and Decreases Dendritic Arborization in Mouse Cortical Neurons by a PKA-Dependent Mechanism.

    Shuto Takeuchi, Takuya Kawanai, Ryosuke Yamauchi, Lu Chen, Tatsunori Miyaoka, Mei Yamada, Satoshi Asano, Atsuko Hayata-Takano, Takanobu Nakazawa, Koji Yano, Naotaka Horiguchi, Shinsaku Nakagawa, Kazuhiro Takuma, James A Waschek, Hitoshi Hashimoto, Yukio Ago

    Frontiers in neuroscience　Vol. 14　p. 521-521　2020　Research paper (scientific journal)

  12. Autism-associated protein kinase D2 regulates embryonic cortical neuron development.

    Kensuke Matsumura, Masayuki Baba, Kazuki Nagayasu, Kana Yamamoto, Momoka Kondo, Kohei Kitagawa, Tomoya Takemoto, Kaoru Seiriki, Atsushi Kasai, Yukio Ago, Atsuko Hayata-Takano, Norihito Shintani, Toshihiko Kuriu, Tokuichi Iguchi, Makoto Sato, Kazuhiro Takuma, Ryota Hashimoto, Hitoshi Hashimoto, Takanobu Nakazawa

    Biochemical and Biophysical Research Communications　Vol. 519　No. 3　p. 626-632　2019/11/12　Research paper (scientific journal)

  13. Psychiatric-disorder-related behavioral phenotypes and cortical hyperactivity in a mouse model of 3q29 deletion syndrome.

    Masayuki Baba, Kazumasa Yokoyama, Kaoru Seiriki, Yuichiro Naka, Kensuke Matsumura, Momoka Kondo, Kana Yamamoto, Misuzu Hayashida, Atsushi Kasai, Yukio Ago, Kazuki Nagayasu, Atsuko Hayata-Takano, Akinori Takahashi, Shun Yamaguchi, Daisuke Mori, Norio Ozaki, Tadashi Yamamoto, Kazuhiro Takuma, Ryota Hashimoto, Hitoshi Hashimoto, Takanobu Nakazawa

    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology　Vol. 44　No. 12　p. 2125-2135　2019/11　Research paper (scientific journal)

  14. Modeling of psychiatric disorders using induced pluripotent stem cell-related technologies.

    Nakazawa T, Hashimoto R, Takuma K, Hashimoto H

    Journal of Pharmacological Sciences　Vol. 140　No. 4　p. 321-324　2019/06　Research paper (scientific journal)

  15. Enriched environment restrains autism spectrum disorder-like phenotypes in mice prenatally exposed to valproic acid.

    Takuma Kazuhiro, Yamaguchi Hiroshi, Hara Yuta, Ago Yukio Ago, Kita-Takano Erika, Hasebe Shigeru, Nakazawa Takanobu, Hashimoto Hitoshi, Matsuda Toshio

    Proceedings for Annual Meeting of The Japanese Pharmacological Society　Vol. 92　No. 0　p. 3-P-022　2019

    Publisher: Japanese Pharmacological Society

  16. Treatment of pregnant mice with valproic acid caused an increase in miR-132 levels in the embryonic brain.

    Nakazawa Takanobu, Hara Yuta, Ago Yukio, Kita-Takano Erika, Hasebe Shigeru, Hashimoto Hitoshi, Matsuda Toshio, Takuma Kazuhiro

    Proceedings for Annual Meeting of The Japanese Pharmacological Society　Vol. 92　No. 0　p. 3-P-023　2019

    Publisher: Japanese Pharmacological Society

  17. mS-11, a mimetic of the mSin3-binding helix in NRSF, ameliorates social interaction deficits in a prenatal valproic acid-induced autism mouse model.

    Kawase H, Ago Y, Naito M, Higuchi M, Hara Y, Hasebe S, Tsukada S, Kasai A, Nakazawa T, Mishina T, Kouji H, Takuma K, Hashimoto H

    Pharmacol Biochem Behav.　Vol. 176　p. 1-5　2019/01　Research paper (scientific journal)

  18. Oxytocin attenuates deficits in social interaction but not recognition memory in a prenatal valproic acid-induced mouse model of autism

    Yuta Hara, Yukio Ago, Momoko Higuchi, Shigeru Hasebe, Takanobu Nakazawa, Hitoshi Hashimoto, Toshio Matsuda, Kazuhiro Takuma

    HORMONES AND BEHAVIOR　Vol. 96　p. 130-136　2017/11　Research paper (scientific journal)

  19. Risperidone and aripiprazole alleviate prenatal valproic acid-induced abnormalities in behaviors and dendritic spine density in mice

    Yuta Hara, Yukio Ago, Atsuki Taruta, Shigeru Hasebe, Haruki Kawase, Wataru Tanabe, Shinji Tsukada, Takanobu Nakazawa, Hitoshi Hashimoto, Toshio Matsuda, Kazuhiro Takuma

    PSYCHOPHARMACOLOGY　Vol. 234　No. 21　p. 3217-3228　2017/11　Research paper (scientific journal)

  20. Environmental enrichment attenuates behavioral abnormalities in valproic acid-exposed autism model mice

    Hiroshi Yamaguchi, Yuta Hara, Yukio Ago, Erika Takano, Shigeru Hasebe, Takanobu Nakazawa, Hitoshi Hashimoto, Toshio Matsuda, Kazuhiro Takuma

    BEHAVIOURAL BRAIN RESEARCH　Vol. 333　p. 67-73　2017/08　Research paper (scientific journal)

  21. Psychopharmacology of combined activation of the serotonin(1A) and sigma(1) receptors

    Yukio Ago, Shigeru Hasebe, Naoki Hiramatsu, Hitoshi Hashimoto, Kazuhiro Takuma, Toshio Matsuda

    EUROPEAN JOURNAL OF PHARMACOLOGY　Vol. 809　p. 172-177　2017/08　Research paper (scientific journal)

  22. Prenatal exposure to valproic acid increases miR-132 levels in the mouse embryonic brain

    Yuta Hara, Yukio Ago, Erika Takano, Shigeru Hasebe, Takanobu Nakazawa, Hitoshi Hashimoto, Toshio Matsuda, Kazuhiro Takuma

    MOLECULAR AUTISM　Vol. 8　2017/06　Research paper (scientific journal)

  23. High-Speed and Scalable Whole-Brain Imaging in Rodents and Primates

    Kaoru Seiriki, Atsushi Kasai, Takeshi Hashimoto, Wiebke Schulze, Misaki Niu, Shun Yamaguchi, Takanobu Nakazawa, Ken-ichi Inoue, Shiori Uezono, Masahiko Takada, Yuichiro Naka, Hisato Igarashi, Masato Tanuma, James A. Waschek, Yukio Ago, Kenji F. Tanaka, Atsuko Hayata-Takano, Kazuki Nagayasu, Norihito Shintani, Ryota Hashimoto, Yasuto Kunii, Mizuki Hino, Junya Matsumoto, Hirooki Yabe, Takeharu Nagai, Katsumasa Fujita, Toshio Matsuda, Kazuhiro Takuma, Akemichi Baba, Hitoshi Hashimoto

    NEURON　Vol. 94　No. 6　p. 1085-+　2017/06　Research paper (scientific journal)

  24. Differential gene expression profiles in neurons generated from lymphoblastoid B-cell line-derived iPS cells frommonozygotic twin cases with treatment-resistant schizophrenia and discordant responses to clozapine

    Takanobu Nakazawa, Masataka Kikuchi, Mitsuru Ishikawa, Hidenaga Yamamori, Kazuki Nagayasu, Takuya Matsumoto, Michiko Fujimoto, Yuka Yasuda, Mikiya Fujiwara, Shota Okada, Kensuke Matsumura, Atsushi Kasai, Atsuko Hayata-Takano, Norihito Shintani, Shusuke Numata, Kazuhiro Takuma, Wado Akamatsu, Hideyuki Okano, Akihiro Nakaya, Hitoshi Hashimoto, Ryota Hashimoto

    SCHIZOPHRENIA RESEARCH　Vol. 181　p. 75-82　2017/03　Research paper (scientific journal)

  25. Regulation of emotional behaviors by juvenile environmental factors.

    Takuma K, Ago Y, Hasebe S, Nakazawa T, Hashimoto H, Matsuda T

    Nihon Yakurigaku Zasshi　Vol. 149　No. 2　p. 76-78　2017/02

    Publisher: The Japanese Pharmacological Society

  26. Anti-anhedonic effect of selective serotonin reuptake inhibitors with affinity for sigma-1 receptors in picrotoxin-treated mice

    S. Hasebe, Y. Ago, Y. Watabe, S. Oka, N. Hiramatsu, T. Tanaka, C. Umehara, H. Hashimoto, K. Takuma, T. Matsuda

    BRITISH JOURNAL OF PHARMACOLOGY　Vol. 174　No. 4　p. 314-327　2017/02　Research paper (scientific journal)

  27. Role of prefrontal serotonergic and dopaminergic systems in encounter-induced hyperactivity in methamphetamine-sensitized mice

    Tanaka T, Ago Y, Umehara C, Imoto E, Hasebe S, Hashimoto H, Takuma K, Matsuda T

    International Journal of Neuropsychopharmacology　Vol. 20　p. 410-421　2016/12　Research paper (scientific journal)

  28. Prostaglandin D-2 signaling mediated by the CRTH2 receptor is involved in MK-801-induced cognitive dysfunction

    Yusuke Onaka, Norihito Shintani, Takanobu Nakazawa, Takuya Kanoh, Yukio Ago, Toshio Matsuda, Ryota Hashimoto, Kazutaka Ohi, Hiroyuki Hirai, Kin-ya Nagata, Masataka Nakamura, Atsushi Kasai, Atsuko Hayata-Takano, Kazuki Nagayasu, Kazuhiro Takuma, Asao Ogawa, Akemichi Baba, Hitoshi Hashimoto

    BEHAVIOURAL BRAIN RESEARCH　Vol. 314　p. 77-86　2016/11　Research paper (scientific journal)

  29. Prenatal Exposure to Histone Deacetylase Inhibitors Affects Gene Expression of Autism-Related Molecules and Delays Neuronal Maturation

    Takuya Kawanai, Yukio Ago, Ryo Watanabe, Aya Inoue, Atsuki Taruta, Yusuke Onaka, Shigeru Hasebe, Hitoshi Hashimoto, Toshio Matsuda, Kazuhiro Takuma

    NEUROCHEMICAL RESEARCH　Vol. 41　No. 10　p. 2574-2584　2016/10　Research paper (scientific journal)

  30. Involvement of GABA(A) receptors in 5-HT1A and sigma(1) receptor synergism on prefrontal dopaminergic transmission under circulating neurosteroid deficiency

    Yukio Ago, Shigeru Hasebe, Naoki Hiramatsu, Kazuya Mori, Yuji Watabe, Yusuke Onaka, Hitoshi Hashimoto, Kazuhiro Takuma, Toshio Matsuda

    PSYCHOPHARMACOLOGY　Vol. 233　No. 17　p. 3125-3134　2016/09　Research paper (scientific journal)

  31. Distribution of Silver Nanoparticles to Breast Milk and Their Biological Effects on Breast-Fed Offspring Mice

    Yuki Morishita, Yasuo Yoshioka, Yuya Takimura, Yuki Shimizu, Yuki Namba, Nao Nojiri, Takuya Ishizaka, Keizo Takao, Fumiyoshi Yamashita, Kazuhiro Takuma, Yukio Ago, Kazuya Nagano, Yohei Mukai, Haruhiko Kamada, Shin-ichi Tsunoda, Shigeru Saito, Toshio Matsuda, Mitsuru Hashida, Tsuyoshi Miyakawa, Kazuma Higashisaka, Yasuo Tsutsumi

    ACS NANO　Vol. 10　No. 9　p. 8180-8191　2016/09　Research paper (scientific journal)

  32. Improvement by Methylphenidate and Atomoxetine of Social Interaction Deficits and Recognition Memory Impairment in a Mouse Model of Valproic Acid-Induced Autism

    Yuta Hara, Yukio Ago, Atsuki Taruta, Keisuke Katashiba, Shigeru Hasebe, Erika Takano, Yusuke Onaka, Hitoshi Hashimoto, Toshio Matsuda, Kazuhiro Takuma

    AUTISM RESEARCH　Vol. 9　No. 9　p. 926-939　2016/09　Research paper (scientific journal)

  33. Methamphetamine-Induced Hyperlocomotion

    Yukio Ago, Kazuhiro Takuma, Toshio Matsuda

    Neuropathology of Drug Addictions and Substance Misuse　Vol. 2　p. 320-328　2016/04/15　Part of collection (book)

    Publisher: Elsevier Inc.

  34. [The novel method female encounter test].

    Ago Y, Hasebe S, Hashimoto H, Takuma K, Matsuda T

    Nihon yakurigaku zasshi. Folia pharmacologica Japonica　Vol. 147　No. 4　p. 230-234　2016/04

    Publisher: The Japanese Pharmacological Society

  35. Rivastigmine improves isolation rearing-induced prepulse inhibition deficits via muscarinic acetylcholine receptors in mice

    Kosuke Higashino, Yukio Ago, Takahiro Umeki, Shigeru Hasebe, Yusuke Onaka, Hitoshi Hashimoto, Kazuhiro Takuma, Toshio Matsuda

    PSYCHOPHARMACOLOGY　Vol. 233　No. 3　p. 521-528　2016/02　Research paper (scientific journal)

  36. Pharmacological profile of encounter-induced hyperactivity in isolation-reared mice

    Shigeru Hasebe, Yukio Ago, Saki Nishiyama, Satoshi Oka, Hitoshi Hashimoto, Kazuhiro Takuma, Toshio Matsuda

    BEHAVIOURAL PHARMACOLOGY　Vol. 26　No. 7　p. 681-690　2015/10　Research paper (scientific journal)

  37. The Female Encounter Test: A Novel Method for Evaluating Reward-Seeking Behavior or Motivation in Mice

    Yukio Ago, Shigeru Hasebe, Saki Nishiyama, Satoshi Oka, Yusuke Onaka, Hitoshi Hashimoto, Kazuhiro Takuma, Toshio Matsuda

    INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY　Vol. 18　No. 11　2015/10　Research paper (scientific journal)

  38. Decreased expression of hippocampal Na+/Ca2+ exchanger isoform-1 by pentylenetetrazole kindling in mice

    Takuya Kawanai, Atsuki Taruta, Aya Inoue, Ryo Watanabe, Yukio Ago, Hitoshi Hashimoto, Shigeru Hasebe, Yasuhiro Ooi, Kazuhiro Takuma, Toshio Matsuda

    EPILEPSY RESEARCH　Vol. 115　p. 109-112　2015/09　Research paper (scientific journal)

  39. Reduced prefrontal dopaminergic activity in valproic acid-treated mouse autism model

    Yuta Hara, Kazuhiro Takuma, Erika Takano, Keisuke Katashiba, Atsuki Taruta, Kosuke Higashino, Hitoshi Hashimoto, Yukio Ago, Toshio Matsuda

    BEHAVIOURAL BRAIN RESEARCH　Vol. 289　p. 39-47　2015/08　Research paper (scientific journal)

  40. Anxiolytic-like effects of restraint during the dark cycle in adolescent mice

    Yuki Ota, Yukio Ago, Tatsunori Tanaka, Shigeru Hasebe, Yui Toratani, Yusuke Onaka, Hitoshi Hashimoto, Kazuhiro Takuma, Toshio Matsuda

    BEHAVIOURAL BRAIN RESEARCH　Vol. 284　p. 103-111　2015/05　Research paper (scientific journal)

  41. Role of the 5-HT1A autoreceptor in the enhancement of fluvoxamine-induced increases in prefrontal dopamine release by adrenalectomy/castration in mice

    Shigeru Hasebe, Naoki Hiramatsu, Yukio Ago, Kazuya Mori, Yuji Watabe, Hitoshi Hashimoto, Kazuhiro Takuma, Toshio Matsuda

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 127　No. 2　p. 232-235　2015/02　Research paper (scientific journal)

  42. Transgenerational effects of nanomaterials through paternal exposure

    NAMBA Yuki, YOSHIOKA Yasuo, MORISHITA Yuki, TAKIMURA Yuya, SHIMIZU Yuki, AGO Yukio, TAKUMA Kazuhiro, MATSUDA Toshio, HIGASHISAKA Kazuma, TSUTSUMI Yasuo

    Annual Meeting of the Japanese Society of Toxicology　Vol. 42　p. O-1　2015

    Publisher: The Japanese Society of Toxicology

  43. Galantamine promotes adult hippocampal neurogenesis via M-1 muscarinic and alpha 7 nicotinic receptors in mice

    Yuki Kita, Yukio Ago, Kosuke Higashino, Kazuki Asada, Erika Takano, Kazuhiro Takuma, Toshio Matsuda

    INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY　Vol. 17　No. 12　p. 1957-1968　2014/12　Research paper (scientific journal)

  44. Chronic treatment with valproic acid or sodium butyrate attenuates novel object recognition deficits and hippocampal dendritic spine loss in a mouse model of autism

    Kazuhiro Takuma, Yuta Hara, Shunsuke Kataoka, Takuya Kawanai, Yuko Maeda, Ryo Watanabe, Erika Takano, Atsuko Hayata-Takano, Hitoshi Hashimoto, Yukio Ago, Toshio Matsuda

    PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR　Vol. 126　p. 43-49　2014/11　Research paper (scientific journal)

  45. An enriched environment ameliorates memory impairments in PACAP-deficient mice

    Kazuhiro Takuma, Yuko Maeda, Yukio Ago, Toshihiro Ishihama, Kosuke Takemoto, Akira Nakagawa, Norihito Shintani, Hitoshi Hashimoto, Akemichi Baba, Toshio Matsuda

    BEHAVIOURAL BRAIN RESEARCH　Vol. 272　p. 269-278　2014/10　Research paper (scientific journal)

  46. Social crowding in the night-time reduces an anxiety-like behavior and increases social interaction in adolescent mice

    Yukio Ago, Tatsunori Tanaka, Yuki Ota, Mari Kitamoto, Emina Imoto, Kazuhiro Takuma, Toshio Matsuda

    BEHAVIOURAL BRAIN RESEARCH　Vol. 270　p. 37-46　2014/08　Research paper (scientific journal)

  47. The Potential Role of Serotonin(1A) Receptors in Post-weaning Social Isolation-Induced Abnormal Behaviors in Rodents

    Yukio Ago, Kazuhiro Takuma, Toshio Matsuda

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 125　No. 3　p. 237-241　2014/07　Research paper (scientific journal)

  48. Involvement of prefrontal AMPA receptors in encounter stimulation-induced hyperactivity in isolation-reared mice

    Ryota Araki, Yukio Ago, Shigeru Hasebe, Saki Nishiyama, Tatsunori Tanaka, Satoshi Oka, Kazuhiro Takuma, Toshio Matsuda

    INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY　Vol. 17　No. 6　p. 883-893　2014/06　Research paper (scientific journal)

  49. Atomoxetine-Induced Increases in Monoamine Release in the Prefrontal Cortex are Similar in Spontaneously Hypertensive Rats and Wistar-Kyoto Rats

    Yukio Ago, Masato Umehara, Kosuke Higashino, Shigeru Hasebe, Kazumi Fujita, Kazuhiro Takuma, Toshio Matsuda

    NEUROCHEMICAL RESEARCH　Vol. 39　No. 5　p. 825-832　2014/05　Research paper (scientific journal)

  50. Effects of acute and chronic administration of venlafaxine and desipramine on extracellular monoamine levels in the mouse prefrontal cortex and striatum

    Kosuke Higashino, Yukio Ago, Masato Umehara, Yuki Kita, Kazumi Fujita, Kazuhiro Takuma, Toshio Matsuda

    EUROPEAN JOURNAL OF PHARMACOLOGY　Vol. 729　p. 86-93　2014/04　Research paper (scientific journal)

  51. Isolation rearing reduces mechanical allodynia in a mouse model of chronic inflammatory pain

    Naotaka Horiguchi, Yukio Ago, Shigeru Hasebe, Kosuke Higashino, Kazuki Asada, Yuki Kita, Kazuhiro Takuma, Toshio Matsuda

    PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR　Vol. 113　p. 46-52　2013/11　Research paper (scientific journal)

  52. Methylphenidate and venlafaxine attenuate locomotion in spontaneously hypertensive rats, an animal model of attention-deficit/hyperactivity disorder, through (2)-adrenoceptor activation

    Masato Umehara, Yukio Ago, Takuya Kawanai, Kazumi Fujita, Naoki Hiramatsu, Kazuhiro Takuma, Toshio Matsuda

    BEHAVIOURAL PHARMACOLOGY　Vol. 24　No. 4　p. 328-331　2013/08　Research paper (scientific journal)

  53. Role of Social Encounter-Induced Activation of Prefrontal Serotonergic Systems in the Abnormal Behaviors of Isolation-Reared Mice

    Yukio Ago, Ryota Araki, Tatsunori Tanaka, Asuka Sasaga, Saki Nishiyama, Kazuhiro Takuma, Toshio Matsuda

    NEUROPSYCHOPHARMACOLOGY　Vol. 38　No. 8　p. 1535-1547　2013/07　Research paper (scientific journal)

  54. Involvement of spinal 5-HT1A receptors in isolation rearing-induced hypoalgesia in mice

    Naotaka Horiguchi, Yukio Ago, Kazuki Asada, Yuki Kita, Naoki Hiramatsu, Kazuhiro Takuma, Toshio Matsuda

    PSYCHOPHARMACOLOGY　Vol. 227　No. 2　p. 251-261　2013/05　Research paper (scientific journal)

  55. Efficacy of porcine placental extract on climacteric symptoms in peri- and postmenopausal women

    K. Koike, Y. Yamamoto, N. Suzuki, R. Yamazaki, C. Yoshikawa, F. Takano, K. Takuma, K. Sugiura, M. Inoue

    Climacteric　Vol. 16　No. 1　p. 28-35　2013/02　Research paper (scientific journal)

  56. Autism-like behaviours with transient histone hyperacetylation in mice treated prenatally with valproic acid

    Shunsuke Kataoka, Kazuhiro Takuma, Yuta Hara, Yuko Maeda, Yukio Ago, Toshio Matsuda

    INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY　Vol. 16　No. 1　p. 91-103　2013/02　Research paper (scientific journal)

  57. Galantamine increases hippocampal insulin-like growth factor 2 expression via alpha 7 nicotinic acetylcholine receptors in mice

    Yuki Kita, Yukio Ago, Erika Takano, Asako Fukada, Kazuhiro Takuma, Toshio Matsuda

    PSYCHOPHARMACOLOGY　Vol. 225　No. 3　p. 543-551　2013/02　Research paper (scientific journal)

  58. Metabotropic glutamate 2/3 receptor antagonists improve behavioral and prefrontal dopaminergic alterations in the chronic corticosterone-induced depression model in mice

    Yukio Ago, Koji Yano, Ryota Araki, Naoki Hiramatsu, Yuki Kita, Toshiyuki Kawasaki, Hirotaka Onoe, Shigeyuki Chaki, Atsuro Nakazato, Hitoshi Hashimoto, Akemichi Baba, Kazuhiro Takuma, Toshio Matsuda

    Neuropharmacology　Vol. 65　p. 29-38　2013/02　Research paper (scientific journal)

  59. Effects of serotonin-norepinephrine reuptake inhibitors on locomotion and prefrontal monoamine release in spontaneously hypertensive rats

    Masato Umehara, Yukio Ago, Kazumi Fujita, Naoki Hiramatsu, Kazuhiro Takuma, Toshio Matsuda

    EUROPEAN JOURNAL OF PHARMACOLOGY　Vol. 702　No. 1-3　p. 250-257　2013/02　Research paper (scientific journal)

  60. The Glial Sodium-Calcium Exchanger: A New Target for Nitric Oxide-Mediated Cellular Toxicity

    Kazuhiro Takuma, Yukio Ago, Toshio Matsuda

    CURRENT PROTEIN & PEPTIDE SCIENCE　Vol. 14　No. 1　p. 43-50　2013/02

  61. The selective metabotropic glutamate 2/3 receptor agonist MGS0028 reverses psychomotor abnormalities and recognition memory deficits in mice lacking the pituitary adenylate cyclase-activating polypeptide

    Yukio Ago, Naoki Hiramatsu, Toshihiro Ishihama, Keisuke Hazama, Atsuko Hayata-Takano, Yasuhiro Shibasaki, Norihito Shintani, Hitoshi Hashimoto, Toshiyuki Kawasaki, Hirotaka Onoe, Shigeyuki Chaki, Atsuro Nakazato, Akemichi Baba, Kazuhiro Takuma, Toshio Matsuda

    BEHAVIOURAL PHARMACOLOGY　Vol. 24　No. 1　p. 74-77　2013/01　Research paper (scientific journal)

  62. Effect of overexpression of the brain-specific Na+/Ca 2+ exchanger splice variant NCX1.5 on NO cytotoxicity in HEK293 cells

    Yuki Ota, Takuya Kawanai, Ryo Watanabe, Akira Nishimura, Yukio Ago, Kazuhiro Takuma, Toshio Matsuda

    Journal of Pharmacological Sciences　Vol. 121　No. 4　p. 351-354　2013　Research paper (scientific journal)

    Publisher: 4

  63. Synergistic effect of 5-HT1A and σ1 receptor activation on prefrontal dopaminergic transmission under circulating steroid deficiency

    Naoki Hiramatsu, Yukio Ago, Shigeru Hasebe, Akira Nishimura, Kazuya Mori, Kazuhiro Takuma, Toshio Matsuda

    Neuropharmacology　Vol. 75　p. 53-61　2013　Research paper (scientific journal)

    Publisher: Elsevier Ltd

  64. Placental Extract Improves Hippocampal Neuronal Loss and Fear Memory Impairment Resulting From Chronic Restraint Stress in Ovariectomized Mice

    Kazuhiro Takuma, Hiroyuki Mizoguchi, Yoko Funatsu, Yuko Kitahara, Daisuke Ibi, Hiroyuki Kamei, Toshio Matsuda, Koji Koike, Masaki Inoue, Taku Nagai, Kiyofumi Yamada

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 120　No. 2　p. 89-97　2012/10　Research paper (scientific journal)

  65. Neuronal nitric oxide synthase inhibition attenuates the development of L-DOPA-induced dyskinesia in hemi-Parkinsonian rats

    Kazuhiro Takuma, Tatsunori Tanaka, Tsuyoshi Takahashi, Naoki Hiramatsu, Yuki Ota, Yukio Ago, Toshio Matsuda

    EUROPEAN JOURNAL OF PHARMACOLOGY　Vol. 683　No. 1-3　p. 166-173　2012/05　Research paper (scientific journal)

  66. COMBINATION OF CHRONIC STRESS AND OVARIECTOMY CAUSES CONDITIONED FEAR MEMORY DEFICITS AND HIPPOCAMPAL CHOLINERGIC NEURONAL LOSS IN MICE

    K. Takuma, H. Mizoguchi, Y. Funatsu, Y. Hoshina, Y. Himeno, E. Fukuzaki, Y. Kitahara, S. Arai, D. Ibi, H. Kamei, T. Matsuda, K. Koike, M. Inoue, T. Nagai, K. Yamada

    NEUROSCIENCE　Vol. 207　p. 261-273　2012/04　Research paper (scientific journal)

  67. Effect of Prenatal Valproic Acid Exposure on Cortical Morphology in Female Mice

    Yuta Hara, Yuko Maeda, Shunsuke Kataoka, Yukio Ago, Kazuhiro Takuma, Toshio Matsuda

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 118　No. 4　p. 543-546　2012/04　Research paper (scientific journal)

  68. Lithium attenuates methamphetamine-induced hyperlocomotion and behavioral sensitization via modulation of prefrontal monoamine release

    Yukio Ago, Tatsunori Tanaka, Yuki Kita, Hokuto Tokumoto, Kazuhiro Takuma, Toshio Matsuda

    NEUROPHARMACOLOGY　Vol. 62　No. 4　p. 1634-1639　2012/03　Research paper (scientific journal)

  69. Lithium attenuates methamphetamine-induced hyperlocomotion and behavioral sensitization via modulation of prefrontal monoamine release

    Yukio Ago, Tatsunori Tanaka, Yuki Kita, Hokuto Tokumoto, Kazuhiro Takuma, Toshio Matsuda

    NEUROPHARMACOLOGY　Vol. 62　No. 4　p. 1634-1639　2012/03　Research paper (scientific journal)

  70. Efficacy of porcine placental extracts with hormone therapy for postmenopausal women with knee pain

    K. Koike, Y. Yamamoto, N. Suzuki, R. Yamazaki, C. Yoshikawa, K. Takuma, K. Sugiura, M. Inoue

    Climacteric　Vol. 15　No. 1　p. 30-35　2012/02　Research paper (scientific journal)

  71. Pharmacological profiles of galantamine: The involvement of muscarinic receptor.

    Matsuda T, Ago Y, Takuma K

    Jpn. J. Neuropsychopharmacol.　2012/02

    Publisher:

  72. The Selective Metabotropic Glutamate 2/3 Receptor Agonist MG50028 Reverses Isolation Rearing Induced Abnormal Behaviors in Mice

    Yukio Ago, Ryota Araki, Koji Yano, Toshiyuki Kawasaki, Shigeyuki Chaki, Atsuro Nakazato, Hirotaka Onoe, Hitoshi Hashimoto, Akemichi Baba, Kazuhiro Takuma, Toshio Matsuda

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 118　No. 2　p. 295-298　2012/02　Research paper (scientific journal)

  73. The Selective Metabotropic Glutamate 2/3 Receptor Agonist MG50028 Reverses Isolation Rearing Induced Abnormal Behaviors in Mice

    Yukio Ago, Ryota Araki, Koji Yano, Toshiyuki Kawasaki, Shigeyuki Chaki, Atsuro Nakazato, Hirotaka Onoe, Hitoshi Hashimoto, Akemichi Baba, Kazuhiro Takuma, Toshio Matsuda

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 118　No. 2　p. 295-298　2012/02　Research paper (scientific journal)

  74. Pharmacological profiles of galantamine: The involvement of muscarinic receptor

    Toshio Matsuda, Yukio Ago, Kazuhiro Takuma

    Japanese Journal of Neuropsychopharmacology　Vol. 32　No. 1　p. 1-8　2012/02

    Publisher: 1

  75. 妊娠と“くすり”―出生児の精神疾患との関連より―

    田熊一敞, 吾郷由希夫, 松田敏夫

    脳21　2012/01

    Publisher: 株式会社 金芳堂

  76. Donepezil, But Not Galantamine, Blocks Muscarinic Receptor-Mediated In Vitro and In Vivo Responses

    Yukio Ago, Ken Koda, Yuki Ota, Yuki Kita, Asako Fukada, Kazuhiro Takuma, Toshio Matsuda

    SYNAPSE　Vol. 65　No. 12　p. 1373-1377　2011/12　Research paper (scientific journal)

  77. SEA0400, a specific Na+/Ca2+ exchange inhibitor, prevents dopaminergic neurotoxicity in an MPTP mouse model of Parkinson's disease

    Yukio Ago, Toshiyuki Kawasaki, Tetsuaki Nashida, Yuki Ota, Yana Cong, Mari Kitamoto, Teisuke Takahashi, Kazuhiro Takuma, Toshio Matsuda

    NEUROPHARMACOLOGY　Vol. 61　No. 8　p. 1441-1451　2011/12　Research paper (scientific journal)

  78. Donepezil, But Not Galantamine, Blocks Muscarinic Receptor-Mediated In Vitro and In Vivo Responses

    Yukio Ago, Ken Koda, Yuki Ota, Yuki Kita, Asako Fukada, Kazuhiro Takuma, Toshio Matsuda

    SYNAPSE　Vol. 65　No. 12　p. 1373-1377　2011/12　Research paper (scientific journal)

  79. SEA0400, a specific Na+/Ca2+ exchange inhibitor, prevents dopaminergic neurotoxicity in an MPTP mouse model of Parkinson's disease

    Yukio Ago, Toshiyuki Kawasaki, Tetsuaki Nashida, Yuki Ota, Yana Cong, Mari Kitamoto, Teisuke Takahashi, Kazuhiro Takuma, Toshio Matsuda

    NEUROPHARMACOLOGY　Vol. 61　No. 8　p. 1441-1451　2011/12　Research paper (scientific journal)

  80. Preventive Effects of an Enriched Environment on Rodent Psychiatric Disorder Models

    Kazuhiro Takuma, Yukio Ago, Toshio Matsuda

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 117　No. 2　p. 71-76　2011/10　Research paper (scientific journal)

  81. Fluvoxamine enhances prefrontal dopaminergic neurotransmission in adrenalectomized/castrated mice via both 5-HT reuptake inhibition and sigma(1) receptor activation

    Yukio Ago, Koji Yano, Naoki Hiramatsu, Kazuhiro Takuma, Toshio Matsuda

    PSYCHOPHARMACOLOGY　Vol. 217　No. 3　p. 377-386　2011/10　Research paper (scientific journal)

  82. Activation of metabotropic glutamate 2/3 receptors attenuates methamphetamine-induced hyperlocomotion and increase in prefrontal serotonergic neurotransmission

    Yukio Ago, Ryota Araki, Koji Yano, Naoki Hiramatsu, Toshiyuki Kawasaki, Shigeyuki Chaki, Atsuro Nakazato, Hirotaka Onoe, Hitoshi Hashimoto, Akemichi Baba, Kazuhiro Takuma, Toshio Matsuda

    PSYCHOPHARMACOLOGY　Vol. 217　No. 3　p. 443-452　2011/10　Research paper (scientific journal)

  83. Activation of metabotropic glutamate 2/3 receptors attenuates methamphetamine-induced hyperlocomotion and increase in prefrontal serotonergic neurotransmission

    Yukio Ago, Ryota Araki, Koji Yano, Naoki Hiramatsu, Toshiyuki Kawasaki, Shigeyuki Chaki, Atsuro Nakazato, Hirotaka Onoe, Hitoshi Hashimoto, Akemichi Baba, Kazuhiro Takuma, Toshio Matsuda

    PSYCHOPHARMACOLOGY　Vol. 217　No. 3　p. 443-452　2011/10　Research paper (scientific journal)

  84. Fluvoxamine enhances prefrontal dopaminergic neurotransmission in adrenalectomized/castrated mice via both 5-HT reuptake inhibition and sigma(1) receptor activation

    Yukio Ago, Koji Yano, Naoki Hiramatsu, Kazuhiro Takuma, Toshio Matsuda

    PSYCHOPHARMACOLOGY　Vol. 217　No. 3　p. 377-386　2011/10　Research paper (scientific journal)

  85. Preventive Effects of an Enriched Environment on Rodent Psychiatric Disorder Models

    Kazuhiro Takuma, Yukio Ago, Toshio Matsuda

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 117　No. 2　p. 71-76　2011/10　Research paper (scientific journal)

  86. Matrix Metalloproteinase-9 Contributes to Kindled Seizure Development in Pentylenetetrazole-Treated Mice by Converting Pro-BDNF to Mature BDNF in the Hippocampus

    Hiroyuki Mizoguchi, Junya Nakade, Masaki Tachibana, Daisuke Ibi, Eiichi Someya, Hiroyuki Koike, Hiroyuki Kamei, Toshitaka Nabeshima, Shigeyoshi Itohara, Kazuhiro Takuma, Makoto Sawada, Jun Sato, Kiyofumi Yamada

    JOURNAL OF NEUROSCIENCE　Vol. 31　No. 36　p. 12963-12971　2011/09　Research paper (scientific journal)

  87. The specific Na+/Ca2+ exchange inhibitor SEA0400 prevents nitric oxide-induced cytotoxicity in SH-SY5Y cells

    Tetsuaki Nashida, Kazuhiro Takuma, Sayoko Fukuda, Toshiyuki Kawasaki, Teisuke Takahashi, Akemichi Baba, Yukio Ago, Toshio Matsuda

    NEUROCHEMISTRY INTERNATIONAL　Vol. 59　No. 1　p. 51-58　2011/08　Research paper (scientific journal)

  88. The specific Na+/Ca2+ exchange inhibitor SEA0400 prevents nitric oxide-induced cytotoxicity in SH-SY5Y cells

    Tetsuaki Nashida, Kazuhiro Takuma, Sayoko Fukuda, Toshiyuki Kawasaki, Teisuke Takahashi, Akemichi Baba, Yukio Ago, Toshio Matsuda

    NEUROCHEMISTRY INTERNATIONAL　Vol. 59　No. 1　p. 51-58　2011/08　Research paper (scientific journal)

  89. Nicotine ameliorates impairment of working memory in methamphetamine-treated rats

    Hiroyuki Mizoguchi, Daisuke Ibi, Fumiaki Takase, Taku Nagai, Hiroyuki Kamei, Erika Toth, Jun Sato, Kazuhiro Takuma, Kiyofumi Yamada

    BEHAVIOURAL BRAIN RESEARCH　Vol. 220　No. 1　p. 159-163　2011/06　Research paper (scientific journal)

  90. Pharmacological Aspects of the Acetylcholinesterase Inhibitor Galantamine

    Yukio Ago, Ken Koda, Kazuhiro Takuma, Toshio Matsuda

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 116　No. 1　p. 6-17　2011/05

  91. Alterations of emotional and cognitive behaviors in matrix metalloproteinase-2 and -9-deficient mice

    The Open Behavioral Science Journal　Vol. 4　p. 19-25　2010/09

  92. The Na+/Ca2+ exchanger-mediated Ca2+ influx triggers nitric oxide-induced cytotoxicity in cultured astrocytes

    Tatsuya Kitao, Kazuhiro Takuma, Toshiyuki Kawasaki, Yuriko Inoue, Aki Ikehara, Tetsuaki Nashida, Yukio Ago, Toshio Matsuda

    NEUROCHEMISTRY INTERNATIONAL　Vol. 57　No. 1　p. 58-66　2010/08　Research paper (scientific journal)

  93. Effects of acute and chronic administration of atomoxetine and methylphenidate on extracellular levels of noradrenaline, dopamine and serotonin in the prefrontal cortex and striatum of mice

    Ken Koda, Yukio Ago, Yana Cong, Yuki Kita, Kazuhiro Takuma, Toshio Matsuda

    JOURNAL OF NEUROCHEMISTRY　Vol. 114　No. 1　p. 259-270　2010/07　Research paper (scientific journal)

  94. Environmental factors during early developmental period influence psychobehavioral abnormalities in adult PACAP-deficient mice

    Toshihiro Ishihama, Yukio Ago, Norihito Shintani, Hitoshi Hashimoto, Akemichi Baba, Kazuhiro Takuma, Toshio Matsuda

    BEHAVIOURAL BRAIN RESEARCH　Vol. 209　No. 2　p. 274-280　2010/06　Research paper (scientific journal)

  95. Therapeutic potential of nicotine for methamphetamine-induced impairment of sensorimotor gating: involvement of pallidotegmental neurons

    Hiroyuki Mizoguchi, Sawako Arai, Hiroyuki Koike, Daisuke Ibi, Hiroyuki Kamei, Toshitaka Nabeshima, Hyoung-Chun Kim, Kazuhiro Takuma, Kiyofumi Yamada

    PSYCHOPHARMACOLOGY　Vol. 207　No. 2　p. 235-243　2009/12　Research paper (scientific journal)

  96. [Depression and corticosteroid receptors].

    Ago Y, Takuma K, Matsuda T

    Nihon yakurigaku zasshi. Folia pharmacologica Japonica　Vol. 134　No. 6　p. 304-308　2009/12

    Publisher: 6

  97. RAGE-mediated signaling contributes to intraneuronal transport of amyloid-beta and neuronal dysfunction

    Kazuhiro Takuma, Fang Fang, Wensheng Zhang, Shiqiang Yan, Emiko Fukuzaki, Heng Du, Alexander Sosunov, Guy McKhann, Yoko Funatsu, Noritaka Nakamichi, Taku Nagai, Hiroyuki Mizoguchi, Daisuke Ibi, Osamu Hori, Satoshi Ogawa, David M. Stern, Kiyofumi Yamada, Shirley ShiDu Yan

    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA　Vol. 106　No. 47　p. 20021-20026　2009/11　Research paper (scientific journal)

  98. Matrix Metalloprotease-9 Inhibition Improves Amyloid beta-Mediated Cognitive Impairment and Neurotoxicity in Mice

    Hiroyuki Mizoguchi, Kazuhiro Takuma, Emiko Fukuzaki, Daisuke Ibi, Eiichi Someya, Ko-hei Akazawa, Tursun Alkam, Hiroko Tsunekawa, Akihiro Mouri, Yukihiro Noda, Toshitaka Nabeshima, Kiyofumi Yamada

    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS　Vol. 331　No. 1　p. 14-22　2009/10　Research paper (scientific journal)

  99. [Mitochondrial dysfunction and neuronal apoptosis: new molecular approach to prevent Alzheimer's disease].

    Takuma K, Kataoka S, Ago Y, Matsuda T

    Nihon yakurigaku zasshi. Folia pharmacologica Japonica　Vol. 134　p. 180-183　2009/10

    Publisher: 4

  100. Behavioral abnormality and pharmacologic response in social isolation-reared mice

    Hiroyuki Koike, Daisuke Ibi, Hiroyuki Mizoguchi, Taku Nagai, Atsumi Nitta, Kazuhiro Takuma, Toshitaka Nabeshima, Yukio Yoneda, Kiyofumi Yamada

    BEHAVIOURAL BRAIN RESEARCH　Vol. 202　No. 1　p. 114-121　2009/08　Research paper (scientific journal)

  101. Possible Protection by Notoginsenoside R1 against Glutamate Neurotoxicity Mediated by N-methyl-D-aspartate Receptors Composed of an NR1/NR2B Subunit Assembly

    Bin Gu, Noritaka Nakamichi, Wen-Sheng Zhang, Yukary Nakamura, Yuki Kambe, Ryo Fukumori, Kazuhiro Takuma, Kiyofumi Yamada, Takeshi Takarada, Hideo Taniura, Yukio Yoneda

    JOURNAL OF NEUROSCIENCE RESEARCH　Vol. 87　No. 9　p. 2145-2156　2009/07　Research paper (scientific journal)

  102. Neonatal polyI:C treatment in mice results in schizophrenia-like behavioral and neurochemical abnormalities in adulthood.

    Daisuke Ibi, Taku Nagai, Yuko Kitahara, Hiroyuki Mizoguchi, Hiroyuki Koike, Anna Shiraki, Kazuhiro Takuma, Hiroyuki Kamei, Yukihiro Noda, Atsumi Nitta, Toshitaka Nabeshima, Yukio Yoneda, Kiyofumi Yamada

    Neuroscience research　Vol. 64　No. 3　p. 297-305　2009/07

    Publisher: 3

  103. Role of Prefrontal Dopaminergic Neurotransmission in Glucocorticoid Receptor-Mediated Modulation of Methamphetamine-Induced Hyperactivity

    Yukio Ago, Shinsuke Arikawa, Miyuki Yata, Koji Yano, Michikazu Abe, Kazuhiro Takuma, Toshio Matsuda

    SYNAPSE　Vol. 63　No. 1　p. 7-14　2009/01　Research paper (scientific journal)

  104. GABA(B) receptor agonist baclofen improves methamphetamine-induced cognitive deficit in mice

    Sawako Arai, Kazuhiro Takuma, Hiroyuki Mizoguchi, Daisuke Ibi, Taku Nagai, Hiroyuki Kamei, Hyoung-Chun Kim, Kiyofumi Yamada

    EUROPEAN JOURNAL OF PHARMACOLOGY　Vol. 602　No. 1　p. 101-104　2009/01　Research paper (scientific journal)

  105. Involvement of Pallidotegmental Neurons in Methamphetamine- and MK-801-Induced Impairment of Prepulse Inhibition of the Acoustic Startle Reflex in Mice: Reversal by GABA(B) Receptor Agonist Baclofen

    Sawako Arai, Kazuhiro Takuma, Hiroyuki Mizoguchi, Daisuke Ibi, Taku Nagai, Kenji Takahashi, Hiroyuki Kamei, Toshitaka Nabeshima, Kiyofumi Yamada

    NEUROPSYCHOPHARMACOLOGY　Vol. 33　No. 13　p. 3164-3175　2008/12　Research paper (scientific journal)

  106. Ovariectomy increases neuronal amyloid-beta binding alcohol dehydrogenase level in the mouse hippocampus

    Emiko Fukuzaki, Kazuhiro Takuma, Yoko Funatsu, Yukiko Himeno, Yuko Kitahara, Bin Gu, Hiroyuki Mizoguchi, Daisuke Ibi, Koji Koike, Masaki Inoue, Shi Du Yan, Kiyofumi Yamada

    NEUROCHEMISTRY INTERNATIONAL　Vol. 52　No. 7　p. 1358-1364　2008/06　Research paper (scientific journal)

  107. Social isolation rearing-induced impairment of the hippocampal neurogenesis is associated with deficits in spatial memory and emotion-related behaviors in juvenile mice

    Daisuke Ibi, Kazuhiro Takuma, Hiroyuki Koike, Hiroyuki Mizoguchi, Katsuki Tsuritani, Yusuke Kuwahara, Hiroyuki Kamei, Taku Nagai, Yukio Yoneda, Toshitaka Nabeshima, Kiyofumi Yamada

    JOURNAL OF NEUROCHEMISTRY　Vol. 105　No. 3　p. 921-932　2008/05　Research paper (scientific journal)

  108. Role of tissue plasminogen activator in the sensitization of methamphetamine-induced dopamine release in the nucleus accumbens

    Ayumi Fukakusa, Taku Nagai, Hiroyuki Mizoguchi, Noboru Otsuka, Haruhide Kimura, Hiroyuki Kamei, Hyoung-Chun Kim, Toshitaka Nabeshima, Kazuhiro Takuma, Kiyofumi Yamada

    JOURNAL OF NEUROCHEMISTRY　Vol. 105　No. 2　p. 436-444　2008/04　Research paper (scientific journal)

  109. Enhanced activity of hippocampal BACE1 in a mouse model of postmenopausal memory deficits

    Emiko Fukuzaki, Kazuhiro Takuma, Yukiko Himeno, Shigeru Yoshida, Yoko Funatsu, Yuko Kitahara, Hiroyuki Mizoguchi, Daisuke Ibi, Koji Koike, Masaki Inoue, Kiyofumi Yamada

    NEUROSCIENCE LETTERS　Vol. 433　No. 2　p. 141-145　2008/03　Research paper (scientific journal)

  110. Improvement by minocycline of methamphetamine-induced impairment of recognition memory in mice

    Hiroyuki Mizoguchi, Kazuhiro Takuma, Ayumi Fukakusa, Yukio Ito, Akiko Nakatani, Daisuke Ibi, Hyoung-Chun Kim, Kiyofumi Yamada

    PSYCHOPHARMACOLOGY　Vol. 196　No. 2　p. 233-241　2008/02　Research paper (scientific journal)

  111. Tissue plasminogen activator is not involved in methamphetamine-induced neurotoxicity

    Ayumi Fukakusa, Hiroyuki Mizoguchi, Hiroyuki Koike, Toshitaka Nabeshima, Kazuhiro Takuma, Kiyofumi Yamada

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 106　No. 2　p. 321-324　2008/02　Research paper (scientific journal)

  112. Regulation by tissue plasminogen activator of rewarding effects of drugs of abuse

    Taku Nagai, Kazuhiro Takuma, Toshitaka Nabeshima, Kiyofumi Yamada

    Japanese Journal of Neuropsychopharmacology　Vol. 28　No. 1　p. 1-6　2008/02

    Publisher: 1

  113. Beneficial effect of the selective Na+/Ca2+ exchange inhibitor SEA0400 in a mouse model of Parkinson's disease

    Tetsuaki Nashida, Sayoko Fukuda, Toshiyuki Kawasaki, Tatsuya Kitao, Yukio Ago, Kazuhiro Takuma, Toshio Matsuda

    YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN　Vol. 128　p. 172-174　2008　Research paper (scientific journal)

  114. Protective effect of notoginsenoside R1 in Panax notoginseng on glutamate-induced neurotoxicity

    Bin Gu, Yukary Nakamura, Yuki Kambe, Kazuhiro Takuma, Kiyofumi Yamada, Wen-Sheng Zhang, Takeshi Takarada, Noritaka Nakamichi, Yukio Yoneda

    YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN　Vol. 128　p. 184-187　2008　Research paper (scientific journal)

  115. Folia Pharmacol. Jpn

    今泉和則, 原英彰, 伊藤芳久, 田熊一敞, 布村 明彦

    日本薬理学雑誌　Vol. 130　No. 6　2007/12　Research paper (scientific journal)

  116. A dibenzoylmethane derivative protects dopaminergic neurons against both oxidative stress and endoplasmic reticulum stress

    Katsura Takano, Yasuko Kitao, Yoshiyuki Tabata, Hikari Miura, Kosuke Sato, Kazuhiro Takuma, Kiyofumi Yamada, Satoshi Hibino, Tominari Choshi, Munekazu Iinuma, Hiroto Suzuki, Rika Murakami, Masashi Yamada, Satoshi Ogawa, Osamu Hori

    AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY　Vol. 293　No. 6　p. C1884-C1894　2007/12　Research paper (scientific journal)

  117. Activation of post-synaptic dopamine D(1) receptors promotes the release of tissue plasminogen activator in the nucleus accumbens via PKA signaling

    Mina Ito, Taku Nagai, Hiroyuki Mizoguchi, Kosuke Sato, Minoru Hayase, Noboru Otsuka, Ayumi Fukakusa, Nozomi Kumagai, Hyoung-Chun Kim, Toshitaka Nabeshima, Kazuhiro Takuma, Kiyofumi Yamada

    JOURNAL OF NEUROCHEMISTRY　Vol. 103　No. 6　p. 2589-2596　2007/12　Research paper (scientific journal)

  118. Current studies on neuronal death and neurodegenerative diseases.

    Imaizumi K, Hara H, Ito Y, Takuma K, Nunomura A

    Nihon yakurigaku zasshi. Folia pharmacologica Japonica　Vol. 130　No. 6　p. 477-482　2007/12　Research paper (scientific journal)

    Publisher: 6

  119. Ginkgo biloba extract EGb 761 attenuates hippocampal neuronal loss and cognitive dysfunction resulting from chronic restraint stress in ovariectomized rats

    K. Takuma, Y. Hoshina, S. Arai, Y. Himeno, A. Matsuo, Y. Funatsu, Y. Kitahara, D. Ibi, M. Hayase, H. Kamei, H. Mizoguchi, T. Nagai, K. Koike, M. Inoue, K. Yamada

    NEUROSCIENCE　Vol. 149　No. 2　p. 256-262　2007/10　Research paper (scientific journal)

  120. Repeated methamphetamine treatment impairs spatial working memory in rats: reversal by clozapine but not haloperidol

    Taku Nagai, Kazuhiro Takuma, Misato Dohniwa, Daisuke Ibi, Hiroyuki Mizoguchi, Hiroyuki Kamei, Toshitaka Nabeshima, Kiyofumi Yamada

    PSYCHOPHARMACOLOGY　Vol. 194　No. 1　p. 21-32　2007/09　Research paper (scientific journal)

  121. [Behavioral analyses for learning and memory in mice and rats].

    Takuma K, Nagai T, Yamada K

    Nihon yakurigaku zasshi. Folia pharmacologica Japonica　Vol. 130　No. 2　p. 112-116　2007/08

    Publisher: 2

  122. Neural circuits containing pallidotegmental GABAergic neurons are involved in the prepulse inhibition of the startle reflex in mice

    Kenji Takahashi, Taku Nagai, Hiroyuki Kamei, Kenji Maeda, Takahiro Matsuya, Sawako Arai, Hiroyuki Mizoguchi, Yukio Yoneda, Toshitaka Nabeshima, Kazuhiro Takuma, Kiyofumi Yamada

    BIOLOGICAL PSYCHIATRY　Vol. 62　No. 2　p. 148-157　2007/07　Research paper (scientific journal)

  123. Possible involvement of protease-activated receptor-1 in the regulation of morphine-induced dopamine release and hyperlocomotion by the tissue plasminogen activator-plasmin system

    Mina Ito, Taku Nagai, Hiroyuki Mizoguchi, Ayumi Fukakusa, Yutaka Nakanishi, Hiroyuki Kamei, Toshitaka Nabeshima, Kazuhiro Takuma, Kiyofumi Yamada

    JOURNAL OF NEUROCHEMISTRY　Vol. 101　No. 5　p. 1392-1399　2007/06　Research paper (scientific journal)

  124. [Behavioral analysis for spatial working memory in rats with a delayed spatial win-shift task in a radial arm maze].

    Nagai T, Takuma K, Kamei H, Mizuguchi H, Nabeshima T, Yamada K

    Nihon yakurigaku zasshi. Folia pharmacologica Japonica　Vol. 129　No. 6　p. 457-462　2007/06

    Publisher: 6

  125. Dopamine D1 receptors regulate protein synthesis-dependent long-term recognition memory via extracellular signal-regulated kinase 1/2 in the prefrontal cortex

    Taku Nagai, Kazuhiro Takuma, Hiroyuki Kamei, Yukio Ito, Noritaka Nakamichi, Daisuke Ibi, Yutaka Nakanishi, Masaaki Murai, Hiroyuki Mizoguchi, Toshitaka Nabeshima, Kiyofumi Yamada

    LEARNING & MEMORY　Vol. 14　No. 3　p. 117-125　2007/03　Research paper (scientific journal)

  126. Synergistic effects of adenosine A(2A) antagonist and L-DOPA on rotational behaviors in 6-hydroxydopamine-induced hemi-Parkinsonian mouse model

    Takahiro Matsuya, Kazuhiro Takuma, Kosuke Sato, Makoto Asai, Yoshihiro Murakami, Sosuke Miyoshi, Akihiro Noda, Taku Nagai, Hiroyuki Mizoguchi, Shintaro Nishimura, Kiyofumi Yamada

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 103　No. 3　p. 329-332　2007/03　Research paper (scientific journal)

  127. Clozapine prevents a decrease in neurogenesis in mice repeatedly treated with phencyclidine

    Kenji Maeda, Haruhiko Sugino, Tsuyoshi Hirose, Hisashi Kitagawa, Taku Nagai, Hiroyuki Mizoguchi, Kazuhiro Takuma, Kiyofumi Yamada

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 103　No. 3　p. 299-308　2007/03　Research paper (scientific journal)

  128. A novel azaindolizinone derivative ZSET1446 (spiro[imidazo[1,2-a]pyridine-3,2-indan]-2(3H)-one) improves methamphetamine-induced impairment of recognition memory in mice by activating extracellular signal-regulated kinase 1/2

    Yukio Ito, Kazuhiro Takuma, Hiroyuki Mizoguchi, Taku Nagai, Kiyofumi Yamada

    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS　Vol. 320　No. 2　p. 819-827　2007/02　Research paper (scientific journal)

  129. Role for the pallidotegmental GABAergic neurons in the impairment of prepulse inhibition of the acoustic startle reflex in animal models of schizophrenia

    Sawako Arai, Hiroyuki Mizoguchi, Taku Nagai, Hiroyuki Kamei, Kazuhiro Takuma, Kiyofumi Yamada

    YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN　Vol. 127　p. 123-125　2007　Research paper (scientific journal)

  130. Role of receptor for advanced glycation end products on amyloid beta-peptide transport into neurons.

    Emiko Fukuzaki, Kazuhiro Takuma, Hiroyuki Mizoguchi, David M. Stern, Shirley ShiDu Yan, Kiyofumi Yamada

    YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN　Vol. 127　p. 180-182　2007　Research paper (scientific journal)

  131. Social isolation rearing reduces neurogenesis in the hippocampus and impairs cognition and emotion in mice

    Daisuke Ibi, Kazuhiro Takuma, Hiroyuki Koike, Hiroyuki Mizoguchi, Kiyofumi Yamada

    YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN　Vol. 127　p. 129-132　2007　Research paper (scientific journal)

  132. Involvement of matrix metalloproteinase-9 in the development of pentylenetetrazole-induced kindled seizure in mice

    Junya Nakade, Hiroyuki Mizoguchi, Masaki Tachibana, Shigeyoshi Itohara, Toshitaka Nabeshima, Kazuhiro Takuma, Kiyofumi Yamada

    YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN　Vol. 127　p. 173-175　2007　Research paper (scientific journal)

  133. Acetylcholinesterase inhibitors ameliorate the chronic stress-induced memory impairment in ovariectomized mice

    Yoko Funatsu, Kazuhiro Takuma, Yukiko Himeno, Emiko Fukuzaki, Yuko Kitahara, Yuki Hoshina, Hiroyuki Kamei, Hiroyuki Mizoguchi, Taku Nagai, Koji Koike, Masaki Inoue, Kiyofumi Yamada

    YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN　Vol. 127　p. 183-185　2007　Research paper (scientific journal)

  134. Involvement of tissue plasminogen activator-plasmin system in depolarization-evoked dopamine release in the nucleus accumbens of mice

    Mina Ito, Taku Nagai, Hiroyuki Kamei, Noritaka Nakamichi, Toshitaka Nabeshima, Kazuhiro Takuma, Kiyofumi Yamada

    MOLECULAR PHARMACOLOGY　Vol. 70　No. 5　p. 1720-1725　2006/11　Research paper (scientific journal)

  135. The rewards of nicotine: Regulation by tissue plasminogen activator-plasmin system through protease activated receptor-1

    Taku Nagai, Mina Ito, Noritaka Nakamichi, Hiroyuki Mizoguchi, Hiroyuki Kamei, Ayumi Fukakusa, Toshitaka Nabeshima, Kazuhiro Takuma, Kiyofumi Yamada

    JOURNAL OF NEUROSCIENCE　Vol. 26　No. 47　p. 12374-12383　2006/11　Research paper (scientific journal)

  136. Involvement of hippocampal extracellular signal-regulated kinase 1/2 in spatial working memory in rats

    Taku Nagai, Hiroyuki Kamei, Misato Dohniwa, Masanori Takayanagi, Masakazu Suzuki, Takahiro Matsuya, Toshitaka Nabeshima, Kazuhiro Takuma, Kiyofumi Yamada

    NEUROREPORT　Vol. 17　No. 13　p. 1453-1457　2006/09　Research paper (scientific journal)

  137. [Mitochondrial dysfunction and apoptosis in neurodegenerative diseases].

    Takuma K

    Nihon yakurigaku zasshi. Folia pharmacologica Japonica　Vol. 127　No. 5　p. 349-354　2006/05

    Publisher: 5

  138. [Role of tissue plasminogen activator in the rewarding effect of morphine].

    Nagai T, Nabeshima T, Takuma K, Yamada K

    Nihon Arukoru Yakubutsu Igakkai zasshi = Japanese journal of alcohol studies & drug dependence　Vol. 41　p. 23-30　2006/02

    Publisher: 1

  139. Erratum: Effects of memantine and donepezil on amyloid β-induced memory impairment in a delayed-matching to position task in rats (Behavioural Brain Research (2005) 162 (191-199) DOI: 10.1016/j.bbr.2005.02.036)

    Kiyofumi Yamada, Masanori Takayanagi, Hiroyuki Kamei, Taku Nagai, Misato Dohniwa, Kana Kobayashi, Shigeru Yoshida, Tatsuo Ohhara, Kazuhiro Takuma, Toshitaka Nabeshima

    Behavioural Brain Research　Vol. 166　No. 2　2006/01/30　Research paper (scientific journal)

  140. Repeated methamphetamine treatment impairs recognition memory through a failure of novelty-induced ERK1/2 activation in the prefrontal cortex of mice

    H Kamei, T Nagai, H Nakano, Y Togan, M Takayanagi, K Takahashi, K Kobayashi, S Yoshida, K Maeda, K Takuma, T Nabeshima, K Yamada

    BIOLOGICAL PSYCHIATRY　Vol. 59　No. 1　p. 75-84　2006/01　Research paper (scientific journal)

  141. Effects of memantine and donepezil on amyloid beta-induced memory impairment in a delayed-matching to position task in rats

    K Yamada, M Takayanagi, H Kamei, T Nagai, M Dohniwa, K Kobayashi, S Yoshida, T Ohhara, K Takauma, T Nabeshima

    BEHAVIOURAL BRAIN RESEARCH　Vol. 162　No. 2　p. 191-199　2005/07　Research paper (scientific journal)

  142. Modification by the tissue plasminogen activator-plasmin system of morphine-induced dopamine release and hyperlocomotion, but not anti-nociceptive effect in mice

    T Nagai, H Kamei, M Ito, K Hashimoto, K Takuma, T Nabeshima, K Yamada

    JOURNAL OF NEUROCHEMISTRY　Vol. 93　No. 5　p. 1272-1279　2005/06　Research paper (scientific journal)

  143. The role of tissue plasminogen activator in methamphetamine-related reward and sensitization

    T Nagai, Y Noda, K Ishikawa, Y Miyamoto, M Yoshimura, M Ito, M Takayanagi, K Takuma, K Yamada, T Nabeshima

    JOURNAL OF NEUROCHEMISTRY　Vol. 92　No. 3　p. 660-667　2005/02　Research paper (scientific journal)

  144. Role of serotonin 5-HT2c receptor in aggressive behavior induced by long-term social isoloation in mice

    Tomoko Tsuji, Kazuhiro Takuma, Kyoko Matsukura, Yukio Ito, Taku Nagai, Kiyofumi Yamada

    YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN　Vol. 125　p. 106-107　2005　Research paper (scientific journal)

  145. ABAD enhances A beta-induced cell stress via mitochondrial dysfunction

    K Takuma, J Yao, JM Huang, HW Xu, Chen, X, J Luddy, AC Trillat, DM Stern, O Arancio, SSD Yan

    FASEB JOURNAL　Vol. 19　No. 1　p. 597-+　2005/01　Research paper (scientific journal)

  146. Astrocyte apoptosis: implications for neuroprotection

    K Takuma, A Baba, T Matsuda

    PROGRESS IN NEUROBIOLOGY　Vol. 72　No. 2　p. 111-127　2004/02

  147. Possible involvement of astrocytes in neuroprotection by the cognitive enhancer T-588

    A Yamamuro, Y Ago, K Takuma, S Maeda, Y Sakai, A Baba, T Matsuda

    NEUROCHEMICAL RESEARCH　Vol. 28　No. 12　p. 1779-1783　2003/12　Research paper (scientific journal)

  148. Roles of cathepsins in reperfusion-induced apoptosis in cultured astrocytes

    K Takuma, M Kiriu, K Mori, E Lee, R Enomoto, A Baba, T Matsuda

    NEUROCHEMISTRY INTERNATIONAL　Vol. 42　No. 2　p. 153-159　2003/01　Research paper (scientific journal)

  149. Heat shock inhibits hydrogen peroxide-induced apoptosis in cultured astrocytes

    K Takuma, K Mori, E Lee, R Enomoto, A Baba, T Matsuda

    BRAIN RESEARCH　Vol. 946　No. 2　p. 232-238　2002/08　Research paper (scientific journal)

  150. Involvement of nitric oxide in Ca2+ paradox-induced delayed glial death

    K Takuma, T Matsuda, S Asano, J Azuma, A Baba

    PRECLINICAL AND CLINICAL STRATEGIES FOR THE TREATMENT OF NEURODEGENERATIVE, CEREBROVASCULAR AND MENTAL DISORDERS　Vol. 11　p. 124-128　1996　Research paper (international conference proceedings)

  151. Protective effect of taurine against reperfusion injury in cultured rat astrocytes

    T Matsuda, K Takuma, Y Kishida, J Azuma, A Baba

    TAURINE 2　Vol. 403　p. 491-497　1996　Research paper (international conference proceedings)

  152. Possible role of the Na+-Ca2+ exchanger in nitric oxide-induced serotonin release in the striatum of freely moving rats

    T Matsuda, S Asano, K Takuma, P Somboonthum, J Azuma, A Baba

    PRECLINICAL AND CLINICAL STRATEGIES FOR THE TREATMENT OF NEURODEGENERATIVE, CEREBROVASCULAR AND MENTAL DISORDERS　Vol. 11　p. 129-132　1996　Research paper (international conference proceedings)

  153. ORGANIC-SYNTHESIS UTILIZING THE INTERMEDIATES IN BECKMANN FRAGMENTATION OF ALPHA-ALKOXYKETOXIMES

    H FUJIOKA, M MIYAZAKI, T YAMANAKA, H YAMAMOTO, K TAKUMA, H KITAGAWA, Y KITA

    JOURNAL OF PHARMACOBIO-DYNAMICS　Vol. 15　No. 3　p. S40-S40　1992/03　Research paper (scientific journal)

Misc. 205

  1. ヒト染色体3q29領域欠失を導入した自閉スペクトラム症モデルマウスの社会性行動異常はオキシトシンにより回復する

    竹本智哉, 馬場優志, 北川航平, 永安一樹, 永安一樹, 勢力薫, 勢力薫, 早田敦子, 早田敦子, 笠井淳司, 吾郷由希夫, 吾郷由希夫, 田熊一敞, 橋本均, 橋本均, 橋本均, 橋本均, 橋本均, 中澤敬信, 中澤敬信

    日本薬理学雑誌　Vol. 157　No. Supplement　2022

  2. ヒト染色体3q29欠失モデルマウスを用いた精神疾患の分子病態研究

    馬場優志, 勢力薫, 近藤百香, 北川航平, 竹本智哉, 笠井淳司, 吾郷由希夫, 吾郷由希夫, 永安一樹, 永安一樹, 森大輔, 森大輔, 尾崎紀夫, 山本雅, 山本雅, 田熊一敞, 田熊一敞, 橋本亮太, 橋本亮太, 橋本均, 橋本均, 橋本均, 橋本均, 橋本均, 橋本均, 中澤敬信, 中澤敬信, 中澤敬信

    日本薬理学雑誌　Vol. 156　No. Supplement　2021

  3. 3q29領域欠失変異を有する精神疾患患者のiPS精神細胞の機能解析

    近藤百香, 栗生俊彦, 馬場優志, 北川航平, 竹本智哉, 永安一樹, 永安一樹, 山森英長, 山森英長, 安田由華, 安田由華, 藤本美智子, 藤本美智子, 田熊一敞, 田熊一敞, 小野富三人, 小野富三人, 橋本亮太, 橋本亮太, 橋本均, 橋本均, 橋本均, 橋本均, 橋本均, 中澤敬信, 中澤敬信, 中澤敬信

    日本薬理学雑誌　Vol. 156　No. Supplement　2021

  4. 統合失調症様モデルマウスの痛覚感受性低下とセロトニン下行性疼痛抑制系の活性化

    吾郷由希夫, 堀口直剛, 浅田和希, 中川晋作, 松田敏夫, 田熊一敞, 田熊一敞, 田熊一敞

    日本緩和医療薬学会年会プログラム・要旨集　Vol. 13th　2019

  5. iPS細胞を用いた精神・神経疾患研究の現状:創薬への期待 iPS細胞関連技術とヒト型疾患モデルマウスを用いた精神疾患の分子病態解析

    中澤 敬信, 橋本 亮太, 田熊 一敞, 橋本 均

    日本臨床精神神経薬理学会・日本神経精神薬理学会合同年会プログラム・抄録集　Vol. 28回・48回　p. 125-125　2018/11

    Publisher: 日本臨床精神神経薬理学会・日本神経精神薬理学会

  6. ヒトiPS細胞を利用した神経毒性評価の新たな展開と国際動向 iPS細胞関連技術を用いた統合失調症の分子病態解析および神経細胞分化の基盤技術開発

    中澤 敬信, 橋本 亮太, 田熊 一敞, 橋本 均

    日本薬学会年会要旨集　Vol. 138年会　No. 1　p. 132-132　2018/03

    Publisher: (公社)日本薬学会

  7. 前頭葉を標的とする自閉症スペクトラム障害の新たな治療戦略の可能性

    田熊一敞, 原雄大, 吾郷由希夫, 橋本均, 中澤敬信, 松田敏夫

    日本臨床精神神経薬理学会プログラム・抄録集　Vol. 28th　2018

  8. iPS細胞を用いた精神疾患の分子病態研究の最前線と治療 自閉スペクトラム症に高頻度に認めるPOGZ遺伝子座の患者特異的de novo変異の表現型解析

    中澤 敬信, 田熊 一敞, 橋本 亮太, 橋本 均

    日本生物学的精神医学会・日本神経精神薬理学会合同年会プログラム・抄録集　Vol. 39回・47回　p. 130-130　2017/09

    Publisher: 日本生物学的精神医学会・日本神経精神薬理学会

  9. Regulation of neuropsychiatric and neurodevelopmental disorders by juvenile environmental factors

    田熊 一敞, 吾郷 由希夫, 原 雄大, 長谷部 茂, 中澤 敬信, 橋本 均, 松田 敏夫

    日本生物学的精神医学会誌 = Japanese journal of biological psychiatry　Vol. 28　No. 1　p. 22-26　2017/03

    Publisher: 日本生物学的精神医学会 ; 2010-

  10. 自閉スペクトラム症モデルマウスの社会性行動障害に有効な抗てんかん作用を有する医薬品の探索

    三浦大樹, 笠井淳司, 彌永祐輔, 原雄大, 中澤敬信, 吾郷由希夫, 田熊一敞, 橋本均

    日本薬理学会近畿部会プログラム・要旨集　Vol. 132nd　2017

  11. iPS細胞関連技術を用いた統合失調症のトランスレーショナルリサーチ (特集 iPS細胞を用いた精神疾患の研究)

    中澤 敬信, 橋本 亮太, 田熊 一敞, 橋本 均

    分子精神医学　Vol. 16　No. 4　p. 248-254　2016/10

    Publisher: 先端医学社

  12. 自閉症モデルマウスにおける前頭前皮質ドパミン神経系の異常~ADHD治療薬による行動異常の改善

    吾郷由希夫, 原雄大, 前田優子, 長谷部茂, 橋本均, 松田敏夫, 田熊一敞

    日本神経精神薬理学会プログラム・抄録集　Vol. 46th　2016

  13. ドパミン神経賦活薬の慢性投与は胎仔期バルプロ酸曝露マウスの自閉症様行動を改善する

    長谷部茂, 原雄大, 樋口桃子, 吾郷由希夫, 中澤敬信, 橋本均, 松田敏夫, 田熊一敞

    日本生物学的精神医学会(Web)　Vol. 38th　2016

  14. 雌選択性試験：マウス間相互作用を基盤とした新規意欲／報酬探索行動評価系

    吾郷由希夫, 長谷部 茂, 橋本 均, 田熊一敞, 松田敏夫

    日本薬理学雑誌　Vol. 147　No. 4　p. 230-234　2016　Article, review, commentary, editorial, etc. (scientific journal)

  15. 発達環境が神経機能に与える影響

    長谷部 茂, 田熊 一敞

    大阪大学歯学雑誌　Vol. 60　No. 1　p. 21-23　2015/10/20

    Publisher: 大阪大学歯学会

  16. 胎仔期バルプロ酸曝露は雄性マウス前頭皮質のドパミン神経機能を低下させる

    原雄大, 高野恵利加, 樽田淳樹, 片芝圭亮, 東野功典, 吾郷由希夫, 松田敏夫, 田熊一敞

    日本薬学会年会要旨集(CD-ROM)　Vol. 135th　2015

  17. 注意欠陥多動性障害治療薬による前頭葉ドパミン神経活性化を介した胎仔期バルプロ酸曝露マウスの行動異常の改善

    原雄大, 吾郷由希夫, 樽田淳樹, 片芝圭亮, 樋口桃子, 長谷部茂, 尾中勇祐, 橋本均, 松田敏夫, 田熊一敞

    日本薬理学会近畿部会プログラム・要旨集　Vol. 128th　2015

  18. 胎仔期バルプロ酸曝露の神経細胞の成熟に及ぼす影響

    河内琢也, 田熊一敞, 渡部遼, 井上亜耶, 原雄大, 吾郷由希夫, 松田敏夫

    日本薬理学会近畿部会プログラム・要旨集　Vol. 125th　2014/05

  19. GABA(A) receptor modulates prefrontal DA release by both 5-HT1A and sigma(1) receptor activation

    Naoki Hiramatsu, Kazuya Mori, Yuji Watabe, Yukio Ago, Kazuhiro Takuma, Toshio Matsuda

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 124　p. 142P-142P　2014　Research paper, summary (international conference)

  20. Drug use during pregnancy and neuropathology of developmental disorders

    Kazuhiro Takuma, Takuya Kawanai, Yukio Ago, Toshio Matsuda

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 124　p. 47P-47P　2014　Research paper, summary (international conference)

  21. Overcrowding rearing in the nighttime produces anxiolytic- and antidepressant-like effects in juvenile mice

    Tatsunori Tanaka, Yukio Ago, Emina Imoto, Mari Kitamoto, Yuki Ota, Kazuhiro Takuma, Toshio Matsuda

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 124　p. 214P-214P　2014　Research paper, summary (international conference)

  22. 胎仔期バルプロ酸曝露マウスのメタンフェタミン反応性の低下と前頭葉ドパミン神経系異常

    片芝圭亮, 原雄大, 高野恵利加, 樽田淳樹, 東野功典, 前田優子, 吾郷由希夫, 田熊一敞, 松田敏夫

    次世代を担う創薬・医療薬理シンポジウムプログラム・要旨集　Vol. 2014　2014

  23. 胎仔期バルプロ酸曝露マウスの前頭葉ドパミン神経系異常

    原雄大, 高野恵利加, 片芝圭亮, 樽田淳樹, 東野功典, 前田優子, 吾郷由希夫, 田熊一敞, 松田敏夫

    日本臨床精神神経薬理学会・日本神経精神薬理学会合同年会プログラム・抄録集　Vol. 24th-44th　2014

  24. The effect of lactational exposure to silver nanoparticles on emotional functions of infants

    MORISHITA Yuki, MIYAKAWA Tsuyoshi, HIGASHISAKA Kazuma, TSUTSUMI Yasuo, YOSHIOKA Yasuo, TAKIMURA Yuya, NOJIRI Nao, TAKAO Keizo, TAKUMA Kazuhiro, AGO Yukio, TSUNODA Shin-ichi, MATSUDA Toshio

    Annual Meeting of the Japanese Society of Toxicology　Vol. 41　No. 0　p. P-19　2014

    Publisher: The Japanese Society of Toxicology

  25. The transitivity of silver nanoparticles to the infant through the milk

    TAKIMURA Yuya, MIYAGAWA Tsuyoshi, HIGASHISAKA Kazuma, TSUTSUMI Yasuo, YOSHIOKA Yasuo, MORISHITA Yuki, NOJIRI Nao, TAKAO Keizo, TAKUMA Kazuhiro, AGO Yukio, TSUNODA Shin-ichi, MATSUDA Toshio

    Annual Meeting of the Japanese Society of Toxicology　Vol. 41　No. 0　p. O-30　2014

    Publisher: The Japanese Society of Toxicology

  26. 非晶質ナノシリカの妊娠期曝露が仔の情動機能へ及ぼす影響探索

    森下裕貴, 吉岡靖雄, 高雄啓三, 吾郷由希夫, 佐藤宏祐, 野尻奈央, 田中智大, 田熊一敞, 角田慎一, 松田敏夫, 宮川剛, 東阪和馬, 堤康央

    J Toxicol Sci　Vol. 38　No. Supplement　2013/06

  27. Postnatal chronic treatments with sodium valproate and sodium n-butyrate improve cognitive impairment in mice prenatally exposed to sodium valproate

    Shunsuke Kataoka, Kazuhiro Takuma, Yuta Hara, Yuko Maeda, Erika Takano, Yukio Ago, Toshio Matsuda

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 121　p. 81P-81P　2013　Research paper, summary (international conference)

  28. Enhanced response of prefrontal serotonergic system to social encounter in isolation-reared mice

    Ryota Araki, Yukio Ago, Asuka Sasaga, Saki Nishiyama, Kazuhiro Takuma, Toshio Matsuda

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 121　p. 75P-75P　2013　Research paper, summary (international conference)

  29. Effect of voluntary exercise on abnormal behaviors in PACAP-KO mice

    Akira Nakagawa, Rui Fukuyama, Hiroshi Yamaguchi, Norihito Shintani, Hitoshi Hashimoto, Yukio Ago, Kazuhiro Takuma, Toshio Matuda

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 121　p. 81P-81P　2013　Research paper, summary (international conference)

  30. うつ病における海馬

    松田敏夫, 吾郷由希夫, 田熊一敞

    Clinical Neuroscience　Vol. 31　No. 12　p. 1438-1440　2013　Article, review, commentary, editorial, etc. (scientific journal)

  31. グリア細胞Na+/Ca2+交換系の病態生理学的役割

    田熊一敞, 吾郷由希夫, 松田敏夫

    生体の科学　Vol. 64　No. 5　p. 384-385　2013　Article, review, commentary, editorial, etc. (scientific journal)

  32. Prenatal exposure to valproic acid causes sex-dependent behavioral abnormalities and cortical pathology in mice

    S. Kataoka, Y. Hara, Y. Maeda, Y. Ago, K. Takuma, Y. Matsuda

    JOURNAL OF NEUROCHEMISTRY　Vol. 123　p. 24-24　2012/10　Research paper, summary (international conference)

  33. Synergistic neurochemical effect of combined sigma1 and 5-HT1A receptor activation under the circulating neuroactive steroid-deficient conditions

    Y. Ago, N. Hiramatsu, A. Nishimura, K. Takuma, T. Matsuda

    JOURNAL OF NEUROCHEMISTRY　Vol. 123　p. 34-34　2012/10　Research paper, summary (international conference)

  34. Alzheimer's disease drug galantamine increases insulin-like growth factor-2 expression by stimulating alpha 7 nicotinic acetylcholine receptor in the mouse

    Y. Kita, Y. Ago, E. Takano, K. Takuma, T. Matsuda

    JOURNAL OF NEUROCHEMISTRY　Vol. 123　p. 15-15　2012/10　Research paper, summary (international conference)

  35. HDAC阻害作用の精神機能に及ぼす二面性

    片岡駿介, 原雄大, 前田優子, 高野恵利加, 吾郷由希夫, 田熊一敞, 松田敏夫

    次世代を担う若手ファーマ・バイオフォーラム講演要旨集　Vol. 11th　2012/09

  36. 認知機能に着目した非晶質ナノシリカの妊娠期曝露による次世代影響評価

    森下裕貴, 吉岡靖雄, 高雄啓三, 吾郷由希夫, 佐藤宏祐, 野尻奈央, 田熊一敞, 角田慎一, 鍋師裕美, 吉川友章, 松田敏夫, 宮川剛, 堤康央

    J Toxicol Sci　Vol. 37　No. Supplement 1　p. S224-135　2012/07

    Publisher: 日本毒性学会

  37. Involvement of 5-HT_<1A> receptors in fluvoxamine-induced enhancement of prefrontal dopamine release

    HIRAMATSU N, AGO Y, YANO K, TAKUMA K, MATSUDA M

    Vol. 32　No. 2　p. 117-118　2012/04/25

  38. Combined activation of 5-HT1A and sigma(1) receptors enhances prefrontal dopamine release under circulating neuroactive steroid-deficient conditions

    Naoki Hiramatsu, Yukio Ago, Koji Yano, Kazuhiro Takuma, Toshio Matsuda

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 118　p. 119P-119P　2012　Research paper, summary (international conference)

  39. Ameliorative effects of 7-nitroindazole, a neuronal nitric oxide synthase inhibitor, against the development of L-DOPA-induced dyskinesia in 6-hydroxydopamine-lesioned rats

    Yuki Ota, Kazuhiro Takuma, Tsuyoshi Takahashi, Yukio Ago, Toshio Matsuda

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 118　p. 115P-115P　2012　Research paper, summary (international conference)

  40. Sex differences in behavioral abnormalities and cortical pathology in mice prenatally exposed to valproic acid

    Yuta Hara, Shunsuke Kataoka, Yuko Maeda, Yukio Ago, Kazuhiro Takuma, Toshio Matsuda

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 118　p. 67P-67P　2012　Research paper, summary (international conference)

  41. フルボキサミンの薬理作用におけるシグマ1受容体の関与

    吾郷由希夫, 平松直樹, 田熊一敞, 松田敏夫

    ストレス科学　Vol. 27　No. 1　p. 104-111　2012

  42. Antidepressant-like Effect of a Metabotropic Glutamate 2/3 Receptor Antagonist

    Y. Ago, S. Chaki, K. Takuma, T. Matsuda

    CURRENT NEUROPHARMACOLOGY　Vol. 9　p. 1-2　2011/09　Research paper, summary (international conference)

  43. Pharmacological Aspects of the Acetylcholinesterase Inhibitor Galantamine

    Yukio Ago, Ken Koda, Kazuhiro Takuma, Toshio Matsuda

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 116　No. 1　p. 6-17　2011/05　Book review, literature introduction, etc.

  44. Involvement of decreased muscarinic receptor function in prepulse inhibition deficits in mice reared in social isolation

    K. Koda, Y. Ago, K. Yano, M. Nishimura, H. Kobayashi, A. Fukada, K. Takuma, T. Matsuda

    BRITISH JOURNAL OF PHARMACOLOGY　Vol. 162　No. 3　p. 763-772　2011/02

  45. Increased binding of cortical and hippocampal group II metabotropic glutamate receptors in isolation-reared mice

    Toshiyuki Kawasaki, Yukio Ago, Koji Yano, Ryota Araki, Yusuke Washida, Hirotaka Onoe, Shigeyuki Chaki, Atsuro Nakazato, Hitoshi Hashimoto, Akemichi Baba, Kazuhiro Takuma, Toshio Matsuda

    NEUROPHARMACOLOGY　Vol. 60　No. 2-3　p. 397-404　2011/02

  46. The Na+/Ca2+ exchange inhibitor SEA0400 protects dopaminergic neurons from ERK-mediated oxidative stress in MPTP-treated mice

    Yuki Ota, Tetsuaki Nashida, Yukio Ago, Toshiyuki Kawasaki, Teisuke Takahashi, Kazuhiro Takuma, Toshio Matsuda

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 115　p. 192P-192P　2011　Research paper, summary (international conference)

  47. Roles of neuronal nitric oxide synthase in the development of levodopa-induced dyskinesia

    Yana Cong, Tsuyoshi Takahashi, Yukio Ago, Kazuhiro Takuma, Toshio Matsuda

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 115　p. 142P-142P　2011　Research paper, summary (international conference)

  48. Different actions of galantamine and donepezil on M-1 muscarinic receptors contribute to their effects on prepulse inhibition deficits of isolation-reared mice

    Ken Koda, Yukio Ago, Koji Yano, Asako Fukada, Tetsuaki Nashida, Yuki Ota, Kazuhiro Takuma, Toshio Matsuda

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 115　p. 71P-71P　2011　Research paper, summary (international conference)

  49. Receptor for advanced glycation endproducts: a potential target for amyloid-beta peptide-mediated neuropathology

    Kazuhiro Takuma, Toshio Matsuda, Kiyofumi Yamada

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 115　p. 43P-43P　2011　Research paper, summary (international conference)

  50. 胎仔期バルプロ酸曝露による精神異常行動発現におけるヒストンアセチル化の関与

    前田優子, 片岡駿介, 原雄大, 吾郷由希夫, 田熊一敞, 松田敏夫

    日本薬理学会近畿部会プログラム・要旨集　Vol. 119th　2011

  51. ヒストン脱アセチル化酵素阻害活性を欠いたバルプロ酸アナログ,バルプロミド胎仔期投与の生後の情動行動と大脳皮質細胞数に対する作用

    片岡駿介, 田熊一敞, 原雄大, 前田優子, 吾郷由希夫, 松田敏夫

    日本臨床精神神経薬理学会・日本神経精神薬理学会合同年会プログラム・抄録集　Vol. 21st-41st　2011

  52. ROLE OF ENDOGENOUS PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE IN ADULT HIPPOCAMPAL NEUROGENESIS

    Y. Ago, M. Yoneyama, T. Ishihama, S. Kataoka, K. Kawada, T. Tanaka, K. Ogita, N. Shintani, H. Hashimoto, A. Baba, K. Takuma, T. Matsuda

    NEUROSCIENCE　Vol. 172　p. 554-561　2011/01

  53. Effects of environmental factors during development on abnormal phenotypes in PACAP knock-out mice

    Toshihiro Ishihama, Shunsuke Kataoka, Chika Manabe, Yukio Ago, Norihito Shintani, Hitoshi Hashimoto, Akemichi Baba, Kazuhiro Takuma, Toshio Matsuda

    JOURNAL OF MOLECULAR NEUROSCIENCE　Vol. 42　No. 3　p. 302-303　2010/11　Research paper, summary (international conference)

  54. Effects of acute and chronic administration of atomoxetine and methylphenidate on extracellular levels of noradrenaline, dopamine and serotonin in the prefrontal cortex and striatum of mice

    Ken Koda, Yukio Ago, Yana Cong, Yuki Kita, Kazuhiro Takuma, Toshio Matsuda

    JOURNAL OF NEUROCHEMISTRY　Vol. 114　No. 1　p. 259-270　2010/07

  55. Environmental factors during early developmental period influence psychobehavioral abnormalities in adult PACAP-deficient mice

    Toshihiro Ishihama, Yukio Ago, Norihito Shintani, Hitoshi Hashimoto, Akemichi Baba, Kazuhiro Takuma, Toshio Matsuda

    Behavioural Brain Research　Vol. 209　No. 2　p. 274-280　2010/06/19

  56. Environmental factors during early developmental period influence psychobehavioral abnormalities in adult PACAP-deficient mice

    Toshihiro Ishihama, Yukio Ago, Norihito Shintani, Hitoshi Hashimoto, Akemichi Baba, Kazuhiro Takuma, Toshio Matsuda

    BEHAVIOURAL BRAIN RESEARCH　Vol. 209　No. 2　p. 274-280　2010/06

  57. Fluvoxamine facilitates dopamine release in the prefrontal cortex of adrenalectomized/castrated mice via activation of sigma1 receptors

    K. Yano, Y. Ago, N. Hiramatsu, K. Takuma, T. Matsuda

    INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY　Vol. 13　p. 84-85　2010　Research paper, summary (international conference)

  58. Alzheimer&apos;s disease drug galantamine, but not donepezil, improves social isolation rearing-induced deficits in prepulse inhibition via muscarinic acetylcholine receptors

    Y. Ago, K. Koda, K. Yano, K. Takuma, T. Matsuda

    INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY　Vol. 13　p. 58-58　2010　Research paper, summary (international conference)

  59. Behavioral and neurochemical abnormalities following long-term exposure to glucocorticoids in mice

    Yukio Ago, Koji Yano, Ryota Araki, Kazuhiro Takuma, Toshio Matsuda

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 112　p. 26P-26P　2010　Research paper, summary (international conference)

  60. The Na+/Ca2+ exchange inhibitor SEA0400 protects against dopaminergic neurodegeneration in a mouse model of Parkinson&apos;s disease

    T. Nashida, T. Kawasaki, Y. Cong, S. Fukuda, Y. Ago, K. Takuma, T. Matsuda

    INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY　Vol. 13　p. 191-191　2010　Research paper, summary (international conference)

  61. Roles of neuropeptide PACAP in enriched environment-induced neurogenesis and neurotrophic/growth factor expression in the hippocampus

    Yukio Ago, Masanori Yoneyama, Kiyokazu Ogita, Norihito Shintani, Hitoshi Hashimoto, Akemichi Baba, Kazuhiro Takuma, Toshio Matsuda

    NEUROSCIENCE RESEARCH　Vol. 68　p. E367-E367　2010　Research paper, summary (international conference)

  62. Involvement of sigma(1) receptors in fluvoxamine-induced increases in extracellular dopamine levels in the prefrontal cortex of adrenalectomized/castrated mice

    Koji Yano, Yukio Ago, Naoki Hiramatsu, Kazuhiro Takuma, Toshio Matsuda

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 112　p. 186P-186P　2010　Research paper, summary (international conference)

  63. Preferential activation by fluvoxamine of cortical dopamine neurotransmission in adrenalectomized/castrated mice

    Naoki Hiramatsu, Koji Yano, Yukio Ago, Kazuhiro Takuma, Toshio Matsuda

    NEUROSCIENCE RESEARCH　Vol. 68　p. E116-E116　2010　Research paper, summary (international conference)

  64. Functional analysis of brain cholinergic system in long-term social isolation-reared mice

    Momoe Nishimura, Ken Koda, Koji Yano, Yukio Ago, Kazuhiro Takuma, Toshio Matsuda

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 112　p. 182P-182P　2010　Research paper, summary (international conference)

  65. Effects of cholinergic and glutamatergic drugs on early environmental stress-induced abnormal behaviors in mice

    Yukio Ago, Ryota Araki, Koji Yano, Kazuhiro Takuma, Toshio Matsuda

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 112　p. 16P-16P　2010　Research paper, summary (international conference)

  66. The Na+/Ca2+ exchanger-1 mediates nitric oxide-induced cytotoxicity in astrocytes

    Tetsuaki Nashida, Tatsuya Kitao, Yuriko Inoue, Toshiyuki Kawasaki, Yukio Ago, Kazuhiro Takuma, Toshio Matsuda

    NEUROSCIENCE RESEARCH　Vol. 68　p. E242-E242　2010　Research paper, summary (international conference)

  67. RAGE-mediated signaling contributes to intraneuronal transport of amyloid-beta and neuronal dysfunction

    Kazuhiro Takuma, Fang Fang, Wensheng Zhang, Shiqiang Yan, Emiko Fukuzaki, Heng Du, Alexander Sosunov, Guy McKhann, Yoko Funatsu, Noritaka Nakamichi, Taku Nagai, Hiroyuki Mizoguchi, Daisuke Ibi, Osamu Hori, Satoshi Ogawa, David M. Stern, Kiyofumi Yamada, Shirley ShiDu Yan

    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA　Vol. 106　No. 47　p. 20021-20026　2009/11

  68. アミロイド蛋白により誘発される記憶障害におけるMatrix metalloproteinasesの役割

    溝口 博之, 田熊 一敞, 衣斐 大祐, アルカム・トルソン, 毛利 彰宏, 野田 幸裕, 鍋島 俊隆, 山田 清文

    日本薬理学雑誌　Vol. 134　No. 4　p. 3P-3P　2009/10

    Publisher: (公社)日本薬理学会

  69. INVOLVEMENT OF PREFRONTAL DOPAMINERGIC SYSTEM IN ANTI-DEPRESSANT-LIKE EFFECT OF THE GLUCOCORTICOID RECEPTOR ANTAGONIST

    Y. Ago, K. Yano, K. Koda, Y. Kita, K. Takuma, T. Matsuda

    JOURNAL OF NEUROCHEMISTRY　Vol. 110　p. 167-167　2009/09　Research paper, summary (international conference)

  70. ENVIRONMENTAL FACTORS DURING DEVELOPMENT REGULATE THE BEHAVIORAL PHENOTYPES OF PACAP KNOCKOUT MICE

    T. Ishihama, S. Kataoka, C. Manabe, Y. Ago, N. Shintani, H. Hashimoto, A. Baba, K. Takuma, T. Matsuda

    JOURNAL OF NEUROCHEMISTRY　Vol. 110　p. 264-264　2009/09　Research paper, summary (international conference)

  71. GALANTAMINE ENHANCES CHOLINERGIC NEUROTRANSMISSION IN VIVO IN MOUSE PREFRONTAL CORTEX

    K. Koda, K. Yano, Y. Ago, Y. Kita, K. Takuma, T. Matsuda

    JOURNAL OF NEUROCHEMISTRY　Vol. 110　p. 231-231　2009/09　Research paper, summary (international conference)

  72. Environmental factors in psychiatric disorders: Behavioral pharmacology of long-term social isolation-reared mice

    Yukio Ago, Ken Koda, Koji Yano, Kazuhiro Takuma, Toshio Matsuda

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 109　p. 31P-31P　2009　Research paper, summary (international conference)

  73. Protective effect of the selective Na+/Ca2+ exchange inhibitor SEA0400 against MPTP-induced neurotoxicity

    Tetsuaki Nashida, Takeya Otsuki, Sayoko Fukuda, Toshiyuki Kawasaki, Tatsuya Kitao, Yukio Ago, Kazuhiro Takuma, Toshio Matsuda

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 109　p. 50P-50P　2009　Research paper, summary (international conference)

  74. Beneficial treatment of nicotine in methamphetamine (METH)-induced impairment of sensorimotor gating

    Hiroyuki Mizoguchi, Daisuke Ibi, Hiroyuki Kamai, Toshitaka Nabeshima, H. -C. Kim, Kazuhiro Takuma, Kiyofumi Yamada

    NEUROSCIENCE RESEARCH　Vol. 65　p. S253-S253　2009　Research paper, summary (international conference)

  75. Galantamine increases extracellular acetylcholine levels in mouse prefrontal cortex via dopamine-D-1 receptor activation and acetylcholinesterase inhibition

    Koji Yano, Ken Koda, Yukio Ago, Yuki Kita, Kazuhiro Takuma, Toshio Matsuda

    NEUROSCIENCE RESEARCH　Vol. 65　p. S56-S56　2009　Research paper, summary (international conference)

  76. ミトコンドリア障害と神経系のアポトーシス ―アルツハイマー病解明へのアプローチ―.

    日本薬理学雑誌　Vol. 134 (4), 180-183　2009

  77. うつ病と副腎皮質ステロイドホルモン受容体.

    日本薬理学雑誌　Vol. 134(6):304-308　2009

  78. Role of Prefrontal Dopaminergic Neurotransmission in Glucocorticoid Receptor-Mediated Modulation of Methamphetamine-Induced Hyperactivity

    Yukio Ago, Shinsuke Arikawa, Miyuki Yata, Koji Yano, Michikazu Abe, Kazuhiro Takuma, Toshio Matsuda

    SYNAPSE　Vol. 63　No. 1　p. 7-14　2009/01

  79. Galantamine improves apomorphine-induced deficits in prepulse inhibition via muscarinic ACh receptors in mice

    K. Yano, K. Koda, Y. Ago, H. Kobayashi, T. Kawasaki, K. Takuma, T. Matsuda

    BRITISH JOURNAL OF PHARMACOLOGY　Vol. 156　No. 1　p. 173-180　2009/01

  80. Mitochondrial dysfunction and neuronal apoptosis: new molecular approach to preventing Alzheimer&apos;s disease

    Kazuhiro Takuma, Shunsuke Kataoka, Yukio Ago, Toshio Matsuda

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 109　p. 25P-25P　2009　Research paper, summary (international conference)

  81. Depression and corticosteroid receptors.

    Nippon Yakurigaku Zasshi　Vol. 134(6):304-308　2009

  82. A dibenzoylmethane derivative protects dopaminergic neurons against both oxidative stress and endoplasmic reticulum stress.

    No. 26　p. 48-49　2008/12/25

  83. Antidepressant-like effects of the glucocorticoid receptor antagonist RU-43044 are associated with changes in prefrontal dopamine in mouse models of depression

    Yukio Ago, Shinsuke Arikawa, Miyuki Yata, Koji Yano, Michikazu Abe, Kazuhiro Takuma, Toshio Matsuda

    NEUROPHARMACOLOGY　Vol. 55　No. 8　p. 1355-1363　2008/12

  84. A neuroprotective agent, T-817MA (1-{3-[2-(1-benzothiophen-5-yl) ethoxy]propyl} azetidin-3-ol maleate), prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in mice

    Toshiyuki Kawasaki, Yukio Ago, Tatsuya Kitao, Tetsuaki Nashida, Akiko Takagi, Kazuhiro Takuma, Toshio Matsuda

    NEUROPHARMACOLOGY　Vol. 55　No. 5　p. 654-660　2008/10

  85. 組織プラスミノーゲン活性化因子による依存性薬物の報酬効果の制御

    永井 拓, 田熊 一敞, 鍋島 俊隆, 山田 清文

    日本神経精神薬理学雑誌 = Japanese journal of psychopharmacology　Vol. 28　No. 1　p. 1-6　2008/02/25

  86. Role of receptor for advanced glycation end products (RAGE) as an amyloid beta-peptide carrier into neuron

    Emiko Fukuzaki, Kazuhiro Takuma, Hiroyuki Mizoguchi, David M. Stern, Yan Shirley ShiDu, Kiyofumi Yamada

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 106　p. 142P-142P　2008　Research paper, summary (international conference)

  87. Effects of GABA receptor agonists on cognitive impairment in animal models of schizophrenia

    Sawako Arai, Kazuhiro Takuma, Hiroyuki Mizoguchi, Taku Nagai, Hiroyuki Kamei, Kiyofumi Yamada

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 106　p. 231P-231P　2008　Research paper, summary (international conference)

  88. Involvement of matrix metalloproteinase-9 in the development of pentylenetetrazole-induced kindled seizure in mice

    Nakade Junya, Hiroyuki Mizoguchi, Masaki Tachibana, Shigeyoshi Itohara, Toshitaka Nabeshima, Kazuhiro Takuma, Kiyofumi Yamada

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 106　p. 175P-175P　2008　Research paper, summary (international conference)

  89. Histone modification in methamphetamine-associated contextual memory

    Hiroyuki Mizoguchi, Kazuhiro Takuma, Daisuke Ibi, Eiichi Someya, Taku Nagai, Yan Yijan, Yasuhiko Kanou, Toshitaka Nabeshima, Makoto Sawada, Jun Sato, Kiyofumi Yamada

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 106　p. 138P-138P　2008　Research paper, summary (international conference)

  90. Involvement of cholinergic system relate the chronic stress-induced memory impairment in ovariectomized mice

    Yoko Funatsu, Kazuhiro Takuma, Yukiko Himeno, Emiko Fukuzaki, Yuko Kitahara, Yuki Hoshina, Hiroyuki Kamei, Hiroyuki Mizoguchi, Taku Nagai', Koji Koike, Masaki Inoue, Kiyofumi Yamada

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 106　p. 181P-181P　2008　Research paper, summary (international conference)

  91. Induction of tissue plasminogen activator by repeated methamphetamine treatment is associated with the development of sensitization in methamphetamine-induced dopamine release

    Ayumi Fukakusa, Taku Nagai, Hiroyuki Mizoguchi, Toshitaka Nabeshima, Kazuhiro Takuma, Kiyofumi Yamada

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 106　p. 174P-174P　2008　Research paper, summary (international conference)

  92. Social isolation rearing reduces neurogenesis leading to memory deficit in mice

    Vol. 27　No. 5　p. 298-298　2007/11/25

  93. Effect of nicotine on methamphetamine-induced impairment of working memory in rat

    Vol. 27　No. 5　p. 281-281　2007/11/25

  94. Implication of matrix metalloproteinase-9 in the development of kindling in mice

    Vol. 27　No. 5　p. 270-270　2007/11/25

  95. Role for tPA in the development of sensitization for methamphetamine-induced dopamine release

    Vol. 27　No. 5　p. 291-291　2007/11/25

  96. 29-P3-22 更年期障害モデル動物の記憶障害に対するコリンエステラーゼ阻害薬の改善効果(薬物治療,社会の期待に応える医療薬学を)

    舩津 瑶子, 田熊 一敞, 姫野 友紀子, 福崎 笑子, 北原 裕子, 保科 有希, 亀井 浩行, 溝口 博之, 永井 拓, 小池 浩司, 井上 正樹, 山田 清文

    日本医療薬学会年会講演要旨集　Vol. 17　p. 284-284　2007/09/01

    Publisher: 日本医療薬学会

  97. Role for tissue plasminogen activator in methamphetamine-induced reward, sensitization and cognitive impairment in mice

    YAMADA K, NAGAI T, MIZOGUCHI H, NABESHIMA T, TAKUMA K

    Vol. 42　No. 4　p. 222-223　2007/08/28

  98. 17 beta-Estradiol attenuates hippocampal neuronal loss and cognitive dysfunctim induced by chronic restraint stress in ovariectomized rats

    K. Takuma, A. Matsuo, Y. Himeno, Y. Hoshina, Y. Ohno, Y. Funatsu, S. Arai, H. Kamei, H. Mizoguchi, T. Nagai, K. Koike, M. Inoue, K. Yamada

    NEUROSCIENCE　Vol. 146　No. 1　p. 60-68　2007/04　Rapid communication, short report, research note, etc. (scientific journal)

  99. Development and characterization of a mouse model of postmenopausal memory impairment

    Yukiko Himeno, Kazuhiro Takuma, Yuki Hoshina, Sawako Arai, Yuki Ohno, Yoko Funatsu, Taku Nagai, Hiroyuki Mizoguchi, Koji Koike, Masaki Inoue, Kiyofumi Yamada

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 103　p. 230P-230P　2007　Research paper, summary (international conference)

  100. Social isolation rearing reduces neurogenesis in the hippocampal dentate gyrus of juvenile mice and impairs cognitive and behavioral development.

    Daisuke Ibi, Kazuhiro Takuma, Hiroyuki Koike, Hiroyuki Mizoguchi, Kiyofumi Yamada

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 103　p. 58P-58P　2007　Research paper, summary (international conference)

  101. Implication of the pallidotegmental neurons in methamphetamine- and MK-801-induced impairment of prepulse inhibition of the startle reflex in mice

    Sawako Arai, H. Mizoguchi, T. Nagai, K. Takahashi, H. Kamei, K. Takuma, K. Yamada

    NEUROSCIENCE RESEARCH　Vol. 58　p. S122-S122　2007　Research paper, summary (international conference)

  102. Mitochondrial dysfunction and neuronal apoptosis in Alzheimer's disease

    Kazuhiro Takuma, Emiko Fukuzaki, Taku Nagai, Hiroyuki Mizoguchi, David M. Stern, Shirley ShiDu Yan, Kiyofumi Yamada

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 103　p. 45P-45P　2007　Research paper, summary (international conference)

  103. Role of the tPA-plasmin-PAR1 signaling in nicotine rewards

    Mina Ito, Taku Nagai, Noritaka Nakamichi, Hiroyuki Mizoguchi, Hiroyuki Kamei, Toshitaka Nabeshima, Kazuhiro Takuma, Kiyofumi Yamada

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 103　p. 226P-226P　2007　Research paper, summary (international conference)

  104. Role of dopamine D1 receptor/ERK1/2 signal in protein synthesis-dependent long-term recognition memory

    Taku Nagai, Hiyoruki Kamei, Hiroyuki Mizoguchi, Noritaka Nakamichi, Toshitaka Nabeshima, Makiko Suzuki, Kazuhiro Takuma, Kiyofumi Yamada

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 103　p. 33P-33P　2007　Research paper, summary (international conference)

  105. Minocycline improves the object recognition impairment induced by repeated methamphetamine treatment in mice

    Yukio Ito, Kazuhiro Takuma, Hiroyuki Mizoguchi, Taku Nagai, Toshitaka Nabeshima, Kiyofumi Yamada

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 103　p. 125P-125P　2007　Research paper, summary (international conference)

  106. Molecular Mechanism of Delayed Apoptosis in Astrocytes

    Vol. 45　No. 4　p. 669-680　2006/12/25

  107. グリア細胞と精神機能

    田熊 一敞

    日本薬理学雑誌 : FOLIA PHARMACOLOGICA JAPONICA　Vol. 128　No. 5　p. 354-355　2006/11/01

  108. 01P2-029 更年期障害モデル動物の記憶障害に対するエストロゲンの効果(薬物療法(基礎と臨床),医療薬学の扉は開かれた)

    姫野 友紀子, 田熊 一敞, 保科 有希, 新井 佐和子, 永井 拓, 溝口 博之, 小池 浩司, 井上 正樹, 山田 清文

    日本医療薬学会年会講演要旨集　Vol. 16　p. 522-522　2006/09/01

    Publisher: 日本医療薬学会

  109. 研究者の育成と「子育て」

    田熊 一敞

    日本薬理学雑誌 : FOLIA PHARMACOLOGICA JAPONICA　Vol. 128　No. 2　p. 118-119　2006/08/01

  110. エストロゲンとアルツハイマー病

    田熊 一敞

    日本薬理学雑誌 : FOLIA PHARMACOLOGICA JAPONICA　Vol. 127　No. 4　p. 315-315　2006/04/01

  111. Role of tissue plasminogen activator in the rewarding effect of morphine

    NAGAI Taku, NABESHIMA Toshitaka, TAKUMA Kazuhiro, YAMADA Kiyofumi

    Vol. 41　No. 1　p. 23-30　2006/02/28

  112. Effects of memantine and donepezil on amyloid beta-induced memory impairment in a delayed-matching to position task in rats (vol 162, pg 191, 2005)

    K Yamada, M Takayanagi, H Kamei, T Nagai, M Dohniwa, K Kobayashi, S Yoshida, T Ohhara, K Takuma, T Nabeshima

    BEHAVIOURAL BRAIN RESEARCH　Vol. 166　No. 2　p. 296-296　2006/01　Other

  113. Role of hippocampal extracellular signal-regulated kinase (ERK1/2) phosphorylation in spatial working memory

    M Dohniwa, T Nagai, M Takayanagi, K Kobayashi, K Takuma, T Nabeshima, K Yamada

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 100　p. 205P-205P　2006　Research paper, summary (international conference)

  114. Raloxifene and EGb761 suppress stress-induced memory impairment in ovariectomized rats

    Y Hoshina, K Takuma, A Matsuo, Y Himeno, S Arai, H Kamei, T Nagai, K Koike, M Inoue, K Yamada

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 100　p. 147P-147P　2006　Research paper, summary (international conference)

  115. Role of serotonin 5-HT2C receptor in aggressive behavior induced by social isolation in mice

    Kazuhiro Takuma, Tomoko Tsuji, Hiroyuki Koike, Taku Nagai, Kiyofumi Yamada

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 101　p. 90-90　2006　Research paper, summary (international conference)

  116. Neural circuit for the regulation of prepulse inhibition of the startle reflex in mice

    Sawako Arai, Taku Nagai, Kewi Takahashi, Hiroyuki Kamei, Kazuhiro Takuma, Kiyofumi Yamada

    NEUROSCIENCE RESEARCH　Vol. 55　p. S169-S169　2006　Research paper, summary (international conference)

  117. Neuronal circuits involved in the sensorimotor gating in mice

    KJ Takahashi, T Nagai, H Kamei, K Takuma, K Yamada

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 100　p. 88P-88P　2006　Research paper, summary (international conference)

  118. 中枢神経系のアポトーシスにおけるミトコンドリアの役割に関する研究．

    田熊一敞, 山田清文, 松田敏夫

    日本薬理学雑誌　Vol. 127　2006　Article, review, commentary, editorial, etc. (scientific journal)

  119. Hippocampal EPK phosphorylation related to spatial working memory

    DOHNIWA Misato, NAGAI Taku, TAKAYANAGI Masanori, KOBAYASHI Kana, TAKUMA Kazuhiro, NABESHIMA Toshitaka, YAMADA Kiyofumi

    Vol. 25　No. 6　p. 302-302　2005/12/25

  120. The role of tissue plasminogen activator in methamphetamine-related reward and sensitization

    K Yamada, T Nagai, M Ito, K Takuma, T Nabeshima

    NEUROPSYCHOPHARMACOLOGY　Vol. 30　p. S26-S26　2005/12　Research paper, summary (international conference)

  121. P-425 卵巣摘出によるストレス誘発性精神機能障害とエストロゲン補充効果(1.薬物療法(基礎と臨床)4,医療薬学の未来へ翔(はばた)く-薬剤師の薬剤業務・教育・研究への能動的関わり-)

    保科 有希, 田熊 一敞, 松尾 亜伊, 姫野 友紀子, 新井 佐和子, 亀井 浩行, 永井 拓, 小池 浩司, 井上 正樹, 山田 清文

    日本医療薬学会年会講演要旨集　Vol. 15　p. 335-335　2005/09/01

    Publisher: 日本医療薬学会

  122. P-426 放射状迷路を用いたmethamphetamineにおける記憶障害モデルの作製と抗精神病薬clozapineの効果(1.薬物療法(基礎と臨床)4,医療薬学の未来へ翔(はばた)く-薬剤師の薬剤業務・教育・研究への能動的関わり-)

    洞庭 生悟, 永井 拓, 高柳 匡徳, 小林 香奈, 田熊 一敞, 鍋島 俊隆, 山田 清文

    日本医療薬学会年会講演要旨集　Vol. 15　p. 335-335　2005/09/01

    Publisher: 日本医療薬学会

  123. Mitochondrial dysfunction, endoplasmic reticulum stress, and apoptosis in Alzheimer's disease

    K Takuma, SSD Yan, DM Stern, K Yamada

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 97　No. 3　p. 312-316　2005/03

  124. Sex differences in anxiety and aggression induced by long-term social isolation in mice

    T Tsuji, K Takuma, K Matsukura, T Shouji, T Nagai, K Yamada

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 97　p. 61P-61P　2005　Research paper, summary (international conference)

  125. Effects of memantine and donepezil on A beta 1-40-induced memory impairment in 3-lever operant task

    M Takayanagi, T Nagai, M Dohniwa, K Kobayashi, H Kamei, K Takuma, T Nabeshima, K Yamada

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 97　p. 90P-90P　2005　Research paper, summary (international conference)

  126. The role of tissue plasminogen activator (tPA) in the rewarding effects of methamphetamine

    T Nagai, Y Noda, K Ishikawa, Y Miyamoto, M Ito, M Takayanagi, K Takuma, K Yamada, T Nabeshima

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 97　p. 129P-129P　2005　Research paper, summary (international conference)

  127. グリア細胞の遅発性アポトーシス

    田熊一敞, 山田清文, 松田敏夫

    Clinical Neuroscience (臨床神経科学)　Vol. 23　2005　Article, review, commentary, editorial, etc. (scientific journal)

  128. ABAD enhances A beta-induced cell stress via mitochondrial dysfunction

    K Takuma, J Yao, JM Huang, HW Xu, Chen, X, J Luddy, AC Trillat, DM Stern, O Arancio, SSD Yan

    FASEB JOURNAL　Vol. 19　No. 1　p. 597-+　2005/01

  129. アミロイドβ蛋白誘発神経細胞死におけるアミロイドβ蛋白結合アルコール脱水素酵素(ABAD)の役割

    田熊 一敞, 永井 拓, 山田 清文, ARANCIO Ottavio, STERN David, YAN Shirley ShiDu

    日本薬理学雑誌 : FOLIA PHARMACOLOGICA JAPONICA　Vol. 124　p. 73P-74P　2004/11/01

  130. P-289 少人数問題提起・解決型セミナー : EBMに基づく標準的薬物療法について(19.薬学教育・生涯教育(認定),"薬剤師がつくる薬物治療"-薬・薬・学の連携-)

    山田 清文, 犬飼 舞, 郡司 聖子, 小村 江里, 白井 良枝, 松尾 亜伊, 山本 将孝, 亀井 浩行, 田熊 一敞, 永井 拓

    日本医療薬学会年会講演要旨集　Vol. 14　p. 289-289　2004/09/01

    Publisher: 日本医療薬学会

  131. Role of ABAD in A beta-mediated mitochondrial dysfunction in Alzheimer disease

    J Yao, K Takuma, HW Xu, CD Wang, D Stern, O Arancio, S Du Yan

    NEUROBIOLOGY OF AGING　Vol. 25　p. S61-S61　2004/07　Research paper, summary (international conference)

  132. ABAD directly links A beta to mitochondrial toxicity in Alzheimer's disease

    JW Lustbader, M Cirilli, C Lin, HW Xu, K Takuma, N Wang, C Caspersen, Chen, X, S Pollak, M Chaney, F Trinchese, SM Liu, F Gunn-Moore, LF Lue, DG Walker, P Kuppusamy, ZL Zewier, O Arancio, D Stern, SSD Yan, H Wu

    SCIENCE　Vol. 304　No. 5669　p. 448-452　2004/04

  133. Astrocyte apoptosis: Implications for neuroprotection

    Kazuhiro Takuma, Akemichi Baba, Toshio Matsuda

    Progress in Neurobiology　Vol. 72　No. 2　p. 111-127　2004/03　Book review, literature introduction, etc.

  134. Astrocyte apoptosis: implications for neuroprotection

    K Takuma, A Baba, T Matsuda

    PROGRESS IN NEUROBIOLOGY　Vol. 72　No. 2　p. 111-127　2004/02　Book review, literature introduction, etc.

  135. 脳とプロテアーゼ

    脳21　Vol. 7　No. 2　p. 189-194　2004

  136. Proteases in brain

    Vol. 7　No. 2　p. 189-194　2004

  137. Possible involvement of astrocytes in neuroprotection by the cognitive enhancer T-588

    A Yamamuro, Y Ago, K Takuma, S Maeda, Y Sakai, A Baba, T Matsuda

    NEUROCHEMICAL RESEARCH　Vol. 28　No. 12　p. 1779-1783　2003/12

  138. Possible Involvement of Astrocytes in Neuroprotection by the Cognitive Enhancer T-588

    Akiko Yamamuro, Yukio Ago, Kazuhiro Takuma, Sadaaki Maeda, Yoshiyuki Sakai, Akemichi Baba, Toshio Matsuda

    Neurochemical Research　Vol. 28　No. 12　p. 1779-1783　2003/12

  139. Department of Surgery, College of Physicians & Surgeons, Columbia University

    TAKUMA Kazuhiro

    Vol. 121　No. 2　p. 135-135　2003/02/01

  140. ABAD promotes A beta-induced neurotoxicity in transgenic mice.

    K Takuma, HP Zhang, O Arancio, JL Zweier, DM Stern, SD Yan

    JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 91　p. 85P-85P　2003　Research paper, summary (international conference)

  141. Roles of cathepsins in reperfusion-induced apoptosis in cultured astrocytes

    K Takuma, M Kiriu, K Mori, E Lee, R Enomoto, A Baba, T Matsuda

    NEUROCHEMISTRY INTERNATIONAL　Vol. 42　No. 2　p. 153-159　2003/01

  142. Heat shock inhibits hydrogen peroxide-induced apoptosis in cultured astrocytes

    K Takuma, K Mori, E Lee, R Enomoto, A Baba, T Matsuda

    BRAIN RESEARCH　Vol. 946　No. 2　p. 232-238　2002/08

  143. The nitric oxide donor NOC12 protects cultured astrocytes against apoptosis via a cGMP-dependent mechanism

    K Takuma, P Phuagphong, E Lee, R Enomoto, K Mori, A Baba, T Matsuda

    JAPANESE JOURNAL OF PHARMACOLOGY　Vol. 89　No. 1　p. 64-71　2002/05

  144. Anti-apoptotic effect of SEA0400, a novel and selective inhibitor of the Na+-Ca2+ exchanger, in an in vitro astrocyte injury model

    T Matsuda, K Takuma, N Arakawa, K Takahashi, Y Koyama, A Baba

    JAPANESE JOURNAL OF PHARMACOLOGY　Vol. 88　p. 244P-244P　2002　Research paper, summary (international conference)

  145. Anti-apoptotic effect of cGMP in cultured astrocytes - Inhibition by cGMP-dependent protein kinase of mitochondrial permeable transition pore

    K Takuma, P Phuagphong, E Lee, K Mori, A Baba, T Matsuda

    JOURNAL OF BIOLOGICAL CHEMISTRY　Vol. 276　No. 51　p. 48093-48099　2001/12

  146. Delayed apoptosis and its regulation in astrocytes

    K Takuma

    YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN　Vol. 121　No. 9　p. 663-669　2001/09

  147. Ibudilast attenuates astrocyte apoptosis via cyclic GMP signalling pathway in an in vitro reperfusion model

    K Takuma, E Lee, R Enomoto, K Mori, A Baba, T Matsuda

    BRITISH JOURNAL OF PHARMACOLOGY　Vol. 133　No. 6　p. 841-848　2001/07

  148. SEA0400, a novel and selective inhibitor of the Na+-Ca2+ exchanger, attenuates reperfusion injury in the in vitro and in vivo cerebral ischemic models

    T Matsuda, N Arakawa, K Takuma, Y Kishida, Y Kawasaki, M Sakaue, K Takahashi, T Takahashi, T Suzuki, T Ota, A Hamano-Takahashi, M Onishi, Y Tanaka, K Kameo, A Baba

    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS　Vol. 298　No. 1　p. 249-256　2001/07

  149. 脳グリア細胞のアポトーシスとその制御

    田熊 一敞

    薬学雑誌　Vol. 121　No. 9　p. 663-669　2001

  150. Signaling pathways to prevent astrocyte apoptosis

    Rec. Res. Dev. Neurochem.　Vol. 4　No. 1　p. 89-96　2001

  151. Phosphorylation of histones triggers DNA fragmentation in thymocyte undergoing apoptosis induced by protein phosphatase inhibitors

    Riyo Enomoto, Rina Koyamazaki, Yumi Maruta, Motoko Tanaka, Kazuhiro Takuma, Koichi Mori, Eibai Lee

    Molecular Cell Biology Research Communications　Vol. 4　No. 5　p. 276-281　2001

    Publisher: Academic Press Inc.

  152. Signaling pathways to prevent astrocyte apoptosis

    Vol. 4　No. 1　p. 89-96　2001

  153. Ibudilast attenuates astrocyte apoptosis via cyclic GMP signalling pathway in an in vitro reperfusion model

    K. Takuma, E. Lee, R. Enomoto, K. Mori, A. Baba, T. Matsuda

    British Journal of Pharmacology　Vol. 133　No. 6　p. 841-848　2001

    Publisher: John Wiley and Sons Inc.

  154. CV-2619 protects cultured astrocytes against reperfusion injury via nerve growth factor production

    K Takuma, T Yoshida, E Lee, K Mori, T Kishi, A Baba, T Matsuda

    EUROPEAN JOURNAL OF PHARMACOLOGY　Vol. 406　No. 3　p. 333-339　2000/10

  155. T-588 inhibits astrocyte apoptosis via mitogen-activated protein kinase signal pathway

    K Takuma, T Fujita, Y Kimura, M Tanabe, A Yamamuro, E Lee, K Mori, Y Koyama, A Baba, T Matsuda

    EUROPEAN JOURNAL OF PHARMACOLOGY　Vol. 399　No. 1　p. 1-8　2000/06

  156. T-588 inhibits astrocyte apoptosis via mitogen-activated protein kinase signal pathway

    K Takuma, T Fujita, Y Kimura, M Tanabe, A Yamamuro, E Lee, K Mori, Y Koyama, A Baba, T Matsuda

    EUROPEAN JOURNAL OF PHARMACOLOGY　Vol. 399　No. 1　p. 1-8　2000/06

  157. Signal cascade of Na+/Ca2+ exchanger-involved delayed apoptosis of astrocytes

    K Takuma, T Matsuda, A Baba

    CONTROL AND DISEASES OF SODIUM DEPENDENT TRANSPORT PROTEINS AND ION CHANNELS　Vol. 1208　p. 87-88　2000

  158. Control and Diseases of Sodium Dependent Transport Proteins and Ion Channels

    Elsevier Science, Amsterdam　2000

  159. CV-2619 protects cultured rat astrocytes against reperfusion-induced delayed apoptosis

    TAKUMA K, YOSHIDA T, LEE E, MORI K, KISHI T, BABA A, MATSUDA T

    Eur. J. Pharmacol.　Vol. 406　No. 3　p. 333-339　2000

  160. Control and Diseases of Sodium Dependent Transport Proteins and Ion Channels

    Elsevier Science, Amsterdam　2000

  161. Apoptosis in Ca2+ reperfusion injury of cultured astrocytes: roles of reactive oxygen species and NF-kappa B activation

    K Takuma, E Lee, M Kidawara, K Mori, Y Kimura, A Baba, T Matsuda

    EUROPEAN JOURNAL OF NEUROSCIENCE　Vol. 11　No. 12　p. 4204-4212　1999/12

  162. Apoptosis in Ca2+ reperfusion injury of cultured astrocytes: roles of reactive oxygen species and NF-kappa B activation

    K Takuma, E Lee, M Kidawara, K Mori, Y Kimura, A Baba, T Matsuda

    EUROPEAN JOURNAL OF NEUROSCIENCE　Vol. 11　No. 12　p. 4204-4212　1999/12

  163. Cell injury and its protection in astrocytes

    MATSUDA Toshio, TAKUMA Kazuhiro, LEE Eibai, BABA Akemichi

    Folia Pharmacologica Japonica　Vol. 114　No. 5　p. 281-286　1999

    Publisher: The Japanese Pharmacological Society

  164. Cell injury and its protection in astrocytes

    T. Matsuda, K. Takuma, E. Lee, A. Baba

    Folia Pharmacologica Japonica　Vol. 114　No. 5　p. 281-286　1999　Book review, literature introduction, etc.

  165. Involvement of calcineurin in Ca(2+) paradox-like injury of cultured rat astrocytes

    T Matsuda, K Takuma, S Asano, Y Kishida, H Nakamura, K Mori, S Maeda, A Baba

    JOURNAL OF NEUROCHEMISTRY　Vol. 70　No. 5　p. 2004-2011　1998/05

  166. Apoptosis of astroglial cells

    MATSUDA Toshio, TAKUMA Kazuhiro, LEE Eibai, KIMURA Yuji, FUJITA Takashi, BABA Akemichi

    Folia Pharmacologica Japonica　Vol. 112　No. Suppl 1　p. 24-27　1998

    Publisher: The Japanese Pharmacological Society

  167. Apoptosis of astroglial cells

    MATSUDA Toshio, TAKUMA Kazuhiro, LEE Eibai, KIMURA Yuji, FUJITA Takashi, BABA Akemichi

    Folia Pharmacologica Japonica　Vol. 112　No. Suppl 1　p. 24-27　1998

    Publisher: The Japanese Pharmacological Society

  168. Isoform-specific up-regulation by ouabain of Na+,K+-ATPase in cultured rat astrocytes

    R Hosoi, T Matsuda, S Asano, H Nakamura, H Hashimoto, K Takuma, A Baba

    JOURNAL OF NEUROCHEMISTRY　Vol. 69　No. 5　p. 2189-2196　1997/11

  169. Na+-Ca2+ exchanger: Physiology and pharmacology

    T Matsuda, K Takuma, A Baba

    JAPANESE JOURNAL OF PHARMACOLOGY　Vol. 74　No. 1　p. 1-20　1997/05　Book review, literature introduction, etc.

  170. Ouabain-induced cell proliferation in cultured rat astrocytes

    Y Murata, T Matsuda, K Tamada, R Hosoi, S Asano, K Takuma, K Tanaka, A Baba

    JAPANESE JOURNAL OF PHARMACOLOGY　Vol. 72　No. 4　p. 347-353　1996/12

  171. Ouabain-induced cell proliferation in cultured rat astrocytes

    Y Murata, T Matsuda, K Tamada, R Hosoi, S Asano, K Takuma, K Tanaka, A Baba

    JAPANESE JOURNAL OF PHARMACOLOGY　Vol. 72　No. 4　p. 347-353　1996/12

  172. Role of Na+-Ca2+ exchanger in agonist-induced Ca2+ signaling in cultured rat astrocytes

    K Takuma, T Matsuda, H Hashimoto, J Kitanaka, S Asano, Y Kishida, A Baba

    JOURNAL OF NEUROCHEMISTRY　Vol. 67　No. 5　p. 1840-1845　1996/11

  173. Heat shock protects cultured rat astrocytes in a model of reperfusion injury

    K Takuma, T Matsuda, Y Kishida, S Asano, YH Seong, A Baba

    BRAIN RESEARCH　Vol. 735　No. 2　p. 265-270　1996/10

  174. Ca2+ depletion facilitates taurine release in cultured rat astrocytes

    K Takuma, T Matsuda, Y Kishida, S Asano, J Azuma, A Baba

    JAPANESE JOURNAL OF PHARMACOLOGY　Vol. 72　No. 1　p. 75-78　1996/09

  175. Prostanoid receptor-mediated calcium signaling in cultured rat astrocytes

    J Kitanaka, K Takuma, K Kondo, A Baba

    JAPANESE JOURNAL OF PHARMACOLOGY　Vol. 71　No. 1　p. 85-87　1996/05

  176. Prostanoid receptor-mediated calcium signaling in cultured rat astrocytes

    J Kitanaka, K Takuma, K Kondo, A Baba

    JAPANESE JOURNAL OF PHARMACOLOGY　Vol. 71　No. 1　p. 85-87　1996/05

  177. Involvement of Na+,K+-ATPase in the mitogenic effect of insulin-like growth factor-I on cultured rat astrocytes

    T Matsuda, Y Murata, K Tanaka, R Hosoi, M Hayashi, K Tamada, K Takuma, A Baba

    JOURNAL OF NEUROCHEMISTRY　Vol. 66　No. 2　p. 511-516　1996/02

  178. Taurine 2: Basic and Clinical Aspects

    Plenum, New York　1996

  179. Preclinical and Clinical Strategies for the Treatment of Neurodegenerative ...

    S. Karger AG, Basel　1996

  180. Na+/Ca2+交換輸送蛋白

    日本臨牀　Vol. 54　No. 3　p. 612-617　1996

  181. Involvement of Na+-Ca2+ exchanger in calcium paradox-induced delayed glial death

    Eur. J. Neurosci.　Vol. 8　No. 5　p. 951-958　1996

  182. Taurine 2: Basic and Clinical Aspects

    Kluwer Academic/Plenum Publishers, New York　1996

  183. Preclinical and Clinical Strategies for the Treatment of Neurodegenerative, Cerebrovascular and Mental Disorders

    S. Karger AG, Basel　1996

  184. Na+/Ca2+ exchanger

    Vol. 54　No. 3　p. 612-617　1996

  185. Ca2+ depletion facilitates taurine release in cultured rat astrocytes

    Kazuhiro Takuma, Toshio Matsuda, Yoko Kishida, Shoichi Asano, Junichi Azuma, Akemichi Baba

    Japanese Journal of Pharmacology　Vol. 72　No. 1　p. 75-78　1996

    Publisher: Japanese Pharmacological Society

  186. Involvement of Na+-Ca2+ exchanger in calcium paradox-induced delayed glial death

    EUROPEAN JOURNAL OF NEUROSCIENCE　Vol. 8　No. 5　p. 951-958　1996

  187. Novel benzodioxan derivative, 5-{3-[((2,S)-1,4-benzodioxan-2-ylmethyl)amino]propoxy}-1,3-benzodioxole HCl (MKC-242), with a highly potent and selective agonist activity at rat central serotonin(1A) receptors

    T Matsuda, T Yoshikawa, M Suzuki, S Asano, P Somboonthum, K Takuma, Y Nakano, T Morita, Y Nakasu, HS Kim, M Egawa, A Tobe, A Baba

    JAPANESE JOURNAL OF PHARMACOLOGY　Vol. 69　No. 4　p. 357-366　1995/12

  188. 一酸化窒素による神経終末セロトニン取り込みの抑制作用

    浅野 省一, 松田 敏夫, 田熊 一敞, 馬場 明道

    神経化学　Vol. 34　No. 2　p. 114-115　1995/06/15

  189. 培養アストロサイトカルシウムパラドックス障害におけるNa^+-Ca^<2+>交換系の役割

    田熊 一敞, 松田 敏夫, 橋本 均, 浅野 省一, 馬場 明道

    神経化学　Vol. 34　No. 2　p. 264-265　1995/06/15

  190. INCREASE OF NORADRENALINE RELEASE IN THE HYPOTHALAMUS OF FREELY MOVING RAT BY POSTSYNAPTIC 5-HYDROXYTRYPTAMINE(1A) RECEPTOR ACTIVATION

    M SUZUKI, T MATSUDA, S ASANO, P SOMBOONTHUM, K TAKUMA, A BABA

    BRITISH JOURNAL OF PHARMACOLOGY　Vol. 115　No. 4　p. 703-711　1995/06

  191. NITROPRUSSIDE AND CYCLIC-GMP STIMULATE NA+-CA2+ EXCHANGE ACTIVITY IN NEURONAL PREPARATIONS AND CULTURED RAT ASTROCYTES

    S ASANO, T MATSUDA, K TAKUMA, HS KIM, T SATO, T NISHIKAWA, A BABA

    JOURNAL OF NEUROCHEMISTRY　Vol. 64　No. 6　p. 2437-2441　1995/06

  192. EFFECTS OF SEROTONIN(1A) AGONISTS ON ANOXIA-INDUCED IMPAIRMENT OF PROTEIN-SYNTHESIS IN RAT-BRAIN SLICES

    M SUZUKI, T MATSUDA, P SOMBOONTHUM, S ASANO, K TAKUMA, H NOGI, A BABA

    JAPANESE JOURNAL OF PHARMACOLOGY　Vol. 67　No. 4　p. 403-405　1995/04　Article, review, commentary, editorial, etc. (scientific journal)

  193. INTRACELLULAR ASCORBIC-ACID INHIBITS THE NA+-CA2+ EXCHANGER IN CULTURED RAT ASTROCYTES

    K TAKUMA, T MATSUDA, S ASANO, A BABA

    JOURNAL OF NEUROCHEMISTRY　Vol. 64　No. 4　p. 1536-1540　1995/04

  194. EFFECT OF NITRIC-OXIDE ON CA2+ PARADOX-INDUCED GLIAL-CELL DEATH

    T MATSUDA, K TAKUMA, S ASANO, A BABA

    JOURNAL OF NEUROCHEMISTRY　Vol. 65　p. S54-S54　1995　Research paper, summary (international conference)

  195. CULTURED RAT ASTROCYTES POSSESS NA+-CA2+ EXCHANGER

    K TAKUMA, T MATSUDA, H HASHIMOTO, S ASANO, A BABA

    GLIA　Vol. 12　No. 4　p. 336-342　1994/12

  196. CORTICOTROPIN-RELEASING FACTOR STIMULATES CA2+ INFLUX IN CULTURED RAT ASTROCYTES

    K TAKUMA, T MATSUDA, T YOSHIKAWA, J KITANAKA, M GOTOH, K HAYATA, A BABA

    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS　Vol. 199　No. 3　p. 1103-1107　1994/03

  197. CORTICOTROPIN-RELEASING FACTOR STIMULATES CA2+ INFLUX IN CULTURED RAT ASTROCYTES

    K TAKUMA, T MATSUDA, T YOSHIKAWA, J KITANAKA, M GOTOH, K HAYATA, A BABA

    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS　Vol. 199　No. 3　p. 1103-1107　1994/03

  198. SELECTIVE INDUCTION OF ALPHA-1 ISOFORM OF (NA++K+)-ATPASE BY INSULIN INSULIN-LIKE GROWTH FACTOR-I IN CULTURED RAT ASTROCYTES

    T MATSUDA, Y MURATA, N KAWAMURA, M HAYASHI, K TAMADA, K TAKUMA, S MAEDA, A BABA

    ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS　Vol. 307　No. 1　p. 175-182　1993/11

  199. ORGANIC-SYNTHESIS UTILIZING BECKMANN FRAGMENTATION - HIGHLY STEREOSELECTIVE C-C BOND FORMATION IN THE REACTION OF 2,3-ISOPROPYLIDENEDIOXYCYCLOHEXANONE OXIME ESTERS WITH ORGANOALUMINUM REAGENTS

    H FUJIOKA, M MIYAZAKI, H KITAGAWA, T YAMANAKA, H YAMAMOTO, K TAKUMA, Y KITA

    JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS　No. 21　p. 1634-1636　1993/11

  200. SELECTIVE INDUCTION OF ALPHA-1 ISOFORM OF (NA++K+)-ATPASE BY INSULIN INSULIN-LIKE GROWTH FACTOR-I IN CULTURED RAT ASTROCYTES

    T MATSUDA, Y MURATA, N KAWAMURA, M HAYASHI, K TAMADA, K TAKUMA, S MAEDA, A BABA

    ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS　Vol. 307　No. 1　p. 175-182　1993/11

  201. SEX DIFFERENCE FOR TOLERANCE OF 5-HT1A RECEPTOR-MEDIATED TEMPERATURE AND CORTICOSTERONE RESPONSES IN MICE

    Y NAKANO, T MATSUDA, K TAKUMA, T YOSHIKAWA, A BABA

    EUROPEAN JOURNAL OF PHARMACOLOGY　Vol. 219　No. 2　p. 339-341　1992/08　Article, review, commentary, editorial, etc. (scientific journal)

  202. REDUCTIVE BECKMANN FRAGMENTATION OF ALPHA-ALKOXYCYCLOALKANONE OXIME ACETATES

    H FUJIOKA, H YAMAMOTO, M MIYAZAKI, T YAMANAKA, K TAKUMA, Y KITA

    TETRAHEDRON LETTERS　Vol. 32　No. 39　p. 5367-5368　1991/09

  203. REDUCTIVE BECKMANN FRAGMENTATION OF ALPHA-ALKOXYCYCLOALKANONE OXIME ACETATES

    H FUJIOKA, H YAMAMOTO, M MIYAZAKI, T YAMANAKA, K TAKUMA, Y KITA

    TETRAHEDRON LETTERS　Vol. 32　No. 39　p. 5367-5368　1991/09

  204. ORGANIC-SYNTHESIS UTILIZING BECKMANN FRAGMENTATION - NEW CARBON CARBON BOND FORMATION BY THE REACTION OF ALPHA-ALKOXYCYCLOALKANONE OXIME ACETATES WITH ORGANOALUMINUM REAGENTS

    H FUJIOKA, T YAMANAKA, K TAKUMA, M MIYAZAKI, Y KITA

    JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS　No. 7　p. 533-534　1991/04

  205. ORGANIC-SYNTHESIS UTILIZING BECKMANN FRAGMENTATION - NEW CARBON CARBON BOND FORMATION BY THE REACTION OF ALPHA-ALKOXYCYCLOALKANONE OXIME ACETATES WITH ORGANOALUMINUM REAGENTS

    H FUJIOKA, T YAMANAKA, K TAKUMA, M MIYAZAKI, Y KITA

    JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS　No. 7　p. 533-534　1991/04

Works 4

  1. 糖尿病、神経変性疾患等の病態発現における抗酸化の創薬的意義に関する研究

    2009 -

  2. 創薬を目指した環境要因誘発精神疾患動物でのエピジェネティクス研究

    2009 -

  3. SEA0400の中枢作用に関する研究

    2008 -

  4. 糖尿病、神経変性疾患等の病態発現における抗酸化の創薬的意義に関する研究

    2008 -

Institutional Repository 2

Content Published in the University of Osaka Institutional Repository (OUKA)

  1. 発達環境が神経機能に与える影響

    田熊 一敞, 長谷部 茂

    The Journal of Osaka University Dental Society　Vol. 60　No. 1　p. 21-23　2015/10/20

  2. グリア細胞Na+ －Ca2+交換系の生理的及び病理的意義に関する研究

    田熊 一浩