顔写真

PHOTO

Nakatani Kazuhiko
中谷 和彦
Nakatani Kazuhiko
中谷 和彦
The Institute of Scientific and Industrial Research, Specially Appointed Professor (Full Time)

Education 4

  1. Osaka City University

    - 1987

  2. Osaka City University Graduate School, Division of Natural Science

    - 1987

  3. Osaka City University Faculty of Science

    - 1982

  4. Osaka City University Faculty of Science

    - 1982

Committee Memberships 1

  1. 日本化学会 トピックス委員 Academic society

    1993 -

Professional Memberships 4

  1. 光化学協会

  2. 有機合成化学協会

  3. アメリカ化学会

  4. 日本化学会

Research Areas 10

  1. Nanotechnology/Materials / Biochemistry /

  2. Nanotechnology/Materials / Functional solid-state chemistry /

  3. Nanotechnology/Materials / Synthetic organic chemistry /

  4. Life sciences / Bioorganic chemistry /

  5. Nanotechnology/Materials / Structural/physical organic chemistry /

  6. Nanotechnology/Materials / Molecular biochemistry /

  7. Life sciences / Systems genomics /

  8. Life sciences / Genomics /

  9. Nanotechnology/Materials / Nanobioscience /

  10. Nanotechnology/Materials / Nanomaterials /

Awards 6

  1. 日本化学会学術賞

    2008

  2. 市村学術賞 貢献賞

    2008

  3. 大阪科学賞

    2008

  4. 大阪大学研究・教育功績賞

    2006

  5. 第19回日本IBM科学賞

    2005

  6. 有機合成化学 奨励賞

    1994

Papers 132

  1. NMR-Based Rational Drug Design of G:G Mismatch DNA Binding Ligand Trapping Transient Complex via Disruption of a Key Allosteric Interaction

    Shuhei Sakurabayashi, Kyoko Furuita, Takeshi Yamada, Noriaki Sugiura, Makoto Nomura, Takanori Nakane, Akihiro Kawamoto, Genji Kurisu, Yohei Miyanoiri, Toshimichi Fujiwara, Kazuhiko Nakatani, Chojiro Kojima

    Journal of the American Chemical Society 2025/04/17 Research paper (scientific journal)

    Publisher: American Chemical Society (ACS)
  2. The heterodimer of 2-amino-1,8-naphthyridine and 3-aminoisoquinoline binds to the CTG/CTG triad via hydrogen bonding

    Shuhei Sakurabayashi, Takeshi Yamada, Kazuhiko Nakatani

    Bioorganic & Medicinal Chemistry Letters p. 129985-129985 2024/10 Research paper (scientific journal)

    Publisher: Elsevier BV
  3. Utility of oligonucleotide in upregulating circular RNA production in a cellular model

    Lu Ni, Takeshi Yamada, Kazuhiko Nakatani

    2024/01/25

    Publisher: Research Square Platform LLC
  4. NMR analysis of 15N-labeled naphthyridine carbamate dimer (NCD) to contiguous CGG/CGG units in DNA

    Takeshi Yamada, Shuhei Sakurabayashi, Noriaki Sugiura, Hitoshi Haneoka, Kazuhiko Nakatani

    Chemical Communications 2024 Research paper (scientific journal)

  5. A machine learning approach toward generating the focused molecule library targeting CAG repeat DNA

    Qingwen Chen, Takeshi Yamada, Asako Murata, Ayako Sugai, Yasuyuki Matsushita, Kazuhiko Nakatani

    Digital Discovery 2024 Research paper (scientific journal)

  6. Intracerebral Distribution of CAG Repeat-Binding Small Molecule Visualized by Whole-Brain Imaging.

    Eitaro Murakami, Masayuki Nakamori, Kazuhiko Nakatani, Tomonori Shibata, Kazuki Tainaka

    Bioconjugate chemistry Vol. 34 No. 12 p. 2187-2193 2023/12/20 Research paper (scientific journal)

  7. A New Small Molecule DoNA Binding to CAG Repeat RNA

    Qingwen Chen, Takeshi Yamada, Koichi Miyagawa, Asako Murata, Mitsuo Shoji, Kazuhiko Nakatani

    Bioorganic & Medicinal Chemistry 2023/12 Research paper (scientific journal)

  8. Photoswitchable molecular glue for RNA: reversible photocontrol of structure and function of the ribozyme

    Chikara Dohno, Maki Kimura, Yusuke Fujiwara, Kazuhiko Nakatani

    Nucleic Acids Research 2023/08/24 Research paper (scientific journal)

    Publisher: Oxford University Press (OUP)
  9. Quantitative Microscopic Observation of Base–Ligand Interactions via Hydrogen Bonds by Single-Molecule Counting

    Yusuke Takashima, Yuki Komoto, Takahito Ohshiro, Kazuhiko Nakatani, Masateru Taniguchi

    Journal of the American Chemical Society Vol. 145 No. 2 p. 1310-1318 2023/01/04 Research paper (scientific journal)

    Publisher: American Chemical Society (ACS)
  10. A small molecule binding to TGGAA pentanucleotide repeats that cause spinocerebellar ataxia type 31

    Tomonori Shibata, Kazuhiko Nakatani

    Bioorganic and Medicinal Chemistry Letters Vol. 79 2023/01/01 Research paper (scientific journal)

  11. Inhibitory Effects of Mismatch Binding Molecules on the Repair Reaction of Uracil-Containing DNA

    Anisa Ulhusna, Asako Murata, Kazuhiko Nakatani

    BIOCHEMISTRY 2022/10 Research paper (scientific journal)

  12. NMR determination of the 2:1 binding complex of naphthyridine carbamate dimer (NCD) and CGG/CGG triad in double-stranded DNA

    Takeshi Yamada, Kyoko Furuita, Shuhei Sakurabayashi, Makoto Nomura, Chojiro Kojima, Kazuhiko Nakatani

    Nucleic Acids Research 2022/09/12 Research paper (scientific journal)

    Publisher: Oxford University Press (OUP)
  13. Method for Identifying Sequence Motifs in Pre-miRNAs for Small-Molecule Binding

    Yusuke Takashima, Asako Murata, Kei Iida, Ayako Sugai, Masatoshi Hagiwara, Kazuhiko Nakatani

    ACS CHEMICAL BIOLOGY 2022/09 Research paper (scientific journal)

  14. Premature translation termination mediated non-ER stress induced ATF6 activation by a ligand-dependent ribosomal frameshifting circuit

    Hsiu-Ting Hsu, Asako Murata, Chikara Dohno, Kazuhiko Nakatani, KungYao Chang

    NUCLEIC ACIDS RESEARCH Vol. 50 No. 9 p. 5369-5383 2022/05 Research paper (scientific journal)

  15. HT-SELEX-based identification of binding pre-miRNA hairpin-motif for small molecules.

    Sanjukta Mukherjee, Asako Murata, Ryoga Ishida, Ayako Sugai, Chikara Dohno, Michiaki Hamada, Sudhir Krishna, Kazuhiko Nakatani

    Molecular therapy. Nucleic acids Vol. 27 p. 165-174 2022/03/08 Research paper (scientific journal)

  16. CAG repeat-binding small molecule improves motor coordination impairment in a mouse model of Dentatorubral-pallidoluysian atrophy.

    Yuhei Hasuike, Hana Tanaka, Terence Gall-Duncan, Mustafa Mehkary, Kazuhiko Nakatani, Christopher E Pearson, Shoji Tsuji, Hideki Mochizuki, Masayuki Nakamori

    Neurobiology of disease Vol. 163 p. 105604-105604 2022/02 Research paper (scientific journal)

  17. Mismatch binding ligand upregulated back-splicing reaction producing circular RNA in a cellular model

    Lu Ni, Takeshi Yamada, Asako Murata, Kazuhiko Nakatani

    CHEMICAL COMMUNICATIONS Vol. 58 No. 22 p. 3629-3632 2022/02 Research paper (scientific journal)

  18. Small Molecules Targeting Repeat Sequences Causing Neurological Disorders

    Bimolendu Das, Tomonori Shibata, Kazuhiko Nakatani

    Handbook of Chemical Biology of Nucleic Acids p. 1-31 2022 Part of collection (book)

    Publisher: Springer Nature Singapore
  19. p Possibilities and challenges of small molecule organic compounds for the treatment of repeat diseases

    Kazuhiko Nakatani

    PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES Vol. 98 No. 1 p. 30-48 2022/01 Research paper (scientific journal)

  20. 2-Amino-1,8-naphthyridine Dimer (ANP77), a High-Affinity Binder to the Internal Loops of C/CC and T/CC Sites in Double-Stranded DNA

    Bimolendu Das, Konami Nagano, Gota Kawai, Asako Murata, Kazuhiko Nakatani

    JOURNAL OF ORGANIC CHEMISTRY Vol. 87 No. 1 p. 340-350 2021/12 Research paper (scientific journal)

  21. FAN1 exo- not endo-nuclease pausing on disease-associated slipped-DNA repeats: A mechanism of repeat instability

    Amit Laxmikant Deshmukh, Marie-Christine Caron, Mohiuddin Mohiuddin, Stella Lanni, Gagan B. Panigrahi, Mahreen Khan, Worrawat Engchuan, Natalie Shum, Aisha Faruqui, Peixiang Wang, Ryan K. C. Yuen, Masayuki Nakamori, Kazuhiko Nakatani, Jean-Yves Masson, Christopher E. Pearson

    CELL REPORTS Vol. 37 No. 10 p. 110078-110078 2021/12 Research paper (scientific journal)

  22. Cyclic mismatch binding ligands interact with disease-associated CGG trinucleotide repeats in RNA and suppress their translation.

    Patryk Konieczny, Sanjukta Mukherjee, Ewa Stepniak-Konieczna, Katarzyna Taylor, Daria Niewiadomska, Agnieszka Piasecka, Agnieszka Walczak, Anna Baud, Chikara Dohno, Kazuhiko Nakatani, Krzysztof Sobczak

    Nucleic acids research Vol. 49 No. 16 p. 9479-9495 2021/09/20 Research paper (scientific journal)

  23. Short Tandem Repeat Contractions during in vitro DNA Synthesis by Repeat-Binding Molecules

    Masaki Hagihara, Chikara Dohno, Kaoru Saito, Kazuhiro Sugimoto, Yuta Hishinuma, Yuri Sohma, Tomonori Shibata, Kazuhiko Nakatani

    Chemistry Letters Vol. 50 No. 11 p. 1848-1851 2021/09/07 Research paper (scientific journal)

  24. A small-molecule fluorescence probe ANP77 for sensing RNA internal loop of C, U and A/CC motifs and their binding molecules

    Bimolendu Das, Asako Murata, Kazuhiko Nakatani

    NUCLEIC ACIDS RESEARCH Vol. 49 No. 15 p. 8462-8470 2021/09 Research paper (scientific journal)

  25. Ab initio multi-level layered elongation method and its application to local interaction analysis between DNA bulge and ligand molecules

    Keisuke Hisama, Yuuichi Orimoto, Anna Pomogaeva, Kazuhiko Nakatani, Yuriko Aoki

    JOURNAL OF CHEMICAL PHYSICS Vol. 155 No. 4 2021/07 Research paper (scientific journal)

  26. Speeding drug discovery targeting RNAs: An iterative "RNA selection-compounds screening cycle" for exploring RNA-small molecule pairs

    Tomoko Furuzono, Asako Murata, Satoshi Okuda, Kenji Mizutani, Tsuyoshi Adachi, Kazuhiko Nakatani

    BIOORGANIC & MEDICINAL CHEMISTRY Vol. 36 2021/04 Research paper (scientific journal)

  27. Small molecule-induced trinucleotide repeat contractions during in vitro DNA synthesis.

    Chikara Dohno, Masaki Hagihara, Nursakinah Binti Mohd Zaifuddin, Mizuki Nihei, Kaoru Saito, Kazuhiko Nakatani

    Chemical communications (Cambridge, England) Vol. 57 No. 26 p. 3235-3238 2021/03/01 Research paper (scientific journal)

  28. Small Molecule-Induced Dimerization of Hairpin RNA Interfered with the Dicer Cleavage Reaction.

    Asako Murata, Yuki Mori, Yue Di, Ayako Sugai, Bimolendu Das, Yusuke Takashima, Kazuhiko Nakatani

    Biochemistry Vol. 60 No. 4 p. 245-249 2021/02/02 Research paper (scientific journal)

  29. Small molecule targeting r(UGGAA)n disrupts RNA foci and alleviates disease phenotype in Drosophila model.

    Tomonori Shibata, Konami Nagano, Morio Ueyama, Kensuke Ninomiya, Tetsuro Hirose, Yoshitaka Nagai, Kinya Ishikawa, Gota Kawai, Kazuhiko Nakatani

    Nature communications Vol. 12 No. 1 p. 236-236 2021/01/11 Research paper (scientific journal)

  30. Rational design of a photoswitchable DNA glue enabling high regulatory function and supramolecular chirality transfer

    Nadja A. Simeth, Shotaro Kobayashi, Piermichele Kobauri, Stefano Crespi, Wiktor Szymanski, Kazuhiko Nakatani, Chikara Dohno, Ben L. Feringa

    Chemical Science Vol. 12 No. 26 p. 9207-9220 2021 Research paper (scientific journal)

  31. Chemical Probing of Thymine in the TGG/CGG Triad to Explore the Deamination of 5-Methylcytosine in the CGG Repeat.

    Yuki Yagi, Takeshi Yamada, Kazuhiko Nakatani

    Biochemistry Vol. 59 No. 29 p. 2679-2683 2020/07/28 Research paper (scientific journal)

  32. The dimeric form of 1,3-diaminoisoquinoline derivative rescued the mis-splicing of Atp2a1 and Clcn1 genes in myotonic dystrophy type 1 mouse model.

    Kazuhiko Nakatani, Jun Matsumoto, Masayuki Nakamori, Tatsumasa Okamoto, Asako Murata, Chikara Dohno

    Chemistry (Weinheim an der Bergstrasse, Germany) 2020/05/25 Research paper (scientific journal)

  33. Assembly of ruthenium complexes on double stranded DNA using mismatch binding ligands.

    Lu Ni, Takeshi Yamada, Kazuhiko Nakatani

    Chemical communications (Cambridge, England) 2020/04/28

  34. Structural insights into synthetic ligands targeting A–A pairs in disease-related CAG RNA repeats

    Mukherjee, S, Błaszczyk, L, Rypniewski, W, Falschlunger, C, Micura, R, Murata, A, Dohno, C, Nakatani, K, Kiliszek, A

    Nucl. Acids Res. Vol. 47 No. 20 p. 10906-10913 2019/11 Research paper (scientific journal)

  35. Modulating RNA secondary and tertiary structures by mismatch binding ligands.

    Murata A, Nakamori M, Nakatani K

    Methods (San Diego, Calif.) 2019/05

  36. Inhibition of pre-miRNA-136 processing by Dicer with small molecule BzDANP suggested the formation of ternary complex of pre-miR-136-BzDANP-Dicer.

    Otabe T, Nagano K, Kawai G, Murata A, Nakatani K

    Bioorganic & medicinal chemistry Vol. 27 No. 10 p. 2140-2148 2019/05

  37. A Dimeric 2,9-Diamino-1,10-phenanthroline Derivative Improves Alternative Splicing in Myotonic Dystrophy Type 1 Cell and Mouse Models.

    Li J, Nakamori M, Matsumoto J, Murata A, Dohno C, Kiliszek A, Taylor K, Sobczak K, Nakatani K

    Chemistry (Weinheim an der Bergstrasse, Germany) Vol. 24 No. 68 p. 18115-18122 2018/12

  38. CGG repeat DNA assisted dimerization of CGG/CGG binding molecule through intermolecular disulfide formation.

    Yamada T, Miki S, Ni L, Nakatani K

    Chemical communications (Cambridge, England) Vol. 54 No. 93 p. 13072-13075 2018/11 Research paper (scientific journal)

    Publisher: Royal Society of Chemistry (RSC)
  39. Expanding chemical space of DNA-binding molecules with three base-binding units.

    Yagi Y, Aikawa H, Yamada T, Nakatani K

    Bioorganic & medicinal chemistry letters Vol. 28 No. 17 p. 2894-2898 2018/09 Research paper (scientific journal)

    Publisher: Elsevier BV
  40. Small synthetic molecule-stabilized RNA pseudoknot as an activator for -1 ribosomal frameshifting.

    Matsumoto S, Caliskan N, Rodnina MV, Murata A, Nakatani K

    Nucleic acids research Vol. 46 No. 16 p. 8079-8089 2018/09

  41. Bicyclic and tricyclic C-C mismatch-binding ligands bind to CCG trinucleotide repeat DNAs.

    Shibata T, Nakatani K

    Chemical communications (Cambridge, England) Vol. 54 No. 51 p. 7074-7077 2018/06

  42. Restoration of Ribozyme Tertiary Contact and Function by Using a Molecular Glue for RNA

    Chikara Dohno, Maki Kimura, Kazuhiko Nakatani

    Angewandte Chemie - International Edition Vol. 57 No. 2 p. 506-510 2018/01/08 Research paper (scientific journal)

    Publisher: Wiley-VCH Verlag
  43. PCR under Low Ionic Concentration Buffer Conditions

    Fumie Takei, Misaki Akiyama, Kazuyuki Nobusawa, Norhayati Binti Sabani, Huanwen Han, Kazuhiko Nakatani, Ichiro Yamashita

    CHEMISTRYSELECT Vol. 3 No. 3 p. 973-976 2018/01 Research paper (scientific journal)

  44. 1,3-Di(quinolin-2-yl)guanidine binds to GGCCCC hexanucleotide repeat DNA in C9ORF72

    Tomonori Shibata, Eitaro Murakami, Kazuhiko Nakatani

    Bioorganic and Medicinal Chemistry Letters Vol. 28 No. 14 p. 2364-2368 2018 Research paper (scientific journal)

    Publisher: Elsevier Ltd
  45. Synthesis of Naphthyridine Dimers with Conformational Restriction and Binding to DNA and RNA

    Kazuhiko Nakatani, Nozomi Natsuhara, Yuki Mori, Sanjukta Mukherjee, Bimolendu Das, Asako Murata

    CHEMISTRY-AN ASIAN JOURNAL Vol. 12 No. 23 p. 3077-3087 2017/12 Research paper (scientific journal)

  46. Synthetic ligand promotes gene expression by affecting GC sequence in promoter

    Saki Matsumoto, Kei Iida, Asako Murata, Masatsugu Denawa, Masatoshi Hagiwara, Kazuhiko Nakatani

    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS Vol. 27 No. 15 p. 3391-3394 2017/08 Research paper (scientific journal)

  47. Design and Synthesis of Cyclic Mismatch-Binding Ligands (CMBLs) with Variable Linkers by Ring-Closing Metathesis and their Photophysical and DNA Repeat Binding Properties

    Sanjukta Mukherjee, Chikara Dohno, Kazuhiko Nakatani

    CHEMISTRY-A EUROPEAN JOURNAL Vol. 23 No. 47 p. 11385-11396 2017/08 Research paper (scientific journal)

  48. Synthesis of Naphthyridine Carbamate Dimer (NCD) Derivatives Modified with Alkanethiol and Binding Properties of G-G Mismatch DNA

    Takeshi Yamada, Shouta Miki, Anisa Ul'Husna, Akiko Michikawa, Kazuhiko Nakatani

    ORGANIC LETTERS Vol. 19 No. 16 p. 4163-4166 2017/08 Research paper (scientific journal)

  49. Amphiphilic DNA tiles for controlled insertion and 2D assembly on fluid lipid membranes: the effect on mechanical properties

    Chikara Dohno, Shingo Makishi, Kazuhiko Nakatani, Sonia Contera

    NANOSCALE Vol. 9 No. 9 p. 3051-3058 2017/03 Research paper (scientific journal)

  50. A Ligand That Targets CUG Trinucleotide Repeats

    Jinxing Li, Jun Matsumoto, Li-Ping Bai, Asako Murata, Chikara Dohno, Kazuhiko Nakatani

    CHEMISTRY-A EUROPEAN JOURNAL Vol. 22 No. 42 p. 14881-14889 2016/10 Research paper (scientific journal)

  51. BzDANP, a Small-Molecule Modulator of Pre-miR-29a Maturation by Dicer

    Asako Murata, Takahiro Otabe, Jinhua Zhang, Kazuhiko Nakatani

    ACS CHEMICAL BIOLOGY Vol. 11 No. 10 p. 2790-2796 2016/10 Research paper (scientific journal)

  52. Fluorescence Probe for Detecting CCG Trinucleotide Repeat DNA Expansion and Slip-Out

    Tomonori Shibata, Kazuhiko Nakatani

    CHEMBIOCHEM Vol. 17 No. 18 p. 1685-1688 2016/09 Research paper (scientific journal)

  53. Cyclic mismatch binding ligand CMBL4 binds to the 5 '-T-3 '/5 '-GG-3 ' site by inducing the flipping out of thymine base

    Sanjukta Mukherjee, Chikara Dohno, Kaori Asano, Kazuhiko Nakatani

    NUCLEIC ACIDS RESEARCH Vol. 44 No. 15 p. 7090-7099 2016/09 Research paper (scientific journal)

  54. Development of 2, 7-Diamino-1, 8-Naphthyridine (DANP) Anchored Hairpin Primers for RT-PCR Detection of Chikungunya Virus Infection

    Huixin Chen, Mariya Parimelalagan, Fumie Takei, Hapuarachchige Chanditha Hapuarachchi, Evelyn Siew-Chuan Koay, Lee Ching Ng, Phui San Ho, Kazuhiko Nakatani, Justin Jang Hann Chu

    PLoS Neglected Tropical Diseases Vol. 10 No. 8 2016/08/29 Research paper (scientific journal)

    Publisher: Public Library of Science
  55. Synthesis of 1H-pyrrolo[3,2-h]quinoline-8-amine derivatives that target CTG trinucleotide repeats

    Jun Matsumoto, Jinxing Li, Chikara Dohno, Kazuhiko Nakatani

    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS Vol. 26 No. 15 p. 3761-3764 2016/08 Research paper (scientific journal)

  56. Naphthyridine-Benzoazaquinolone: Evaluation of a Tricyclic System for the Binding to (CAG)(n) Repeat DNA and RNA

    Jinxing Li, Akihiro Sakata, Hanping He, Li-Ping Bai, Asako Murata, Chikara Dohno, Kazuhiko Nakatani

    CHEMISTRY-AN ASIAN JOURNAL Vol. 11 No. 13 p. 1971-1981 2016/07 Research paper (scientific journal)

  57. Synthesis and Photophysical Properties of Fluorescence Molecular Probe for Turn-ON-Type Detection of Cytosine Bulge DNA

    Rajiv Kumar Verma, Fumie Takei, Kazuhiko Nakatani

    ORGANIC LETTERS Vol. 18 No. 13 p. 3170-3173 2016/07 Research paper (scientific journal)

  58. Non-covalent Modification of Double-Stranded DNA at the Mismatch and Bulged Site

    Chikara Dohno, Kazuhiko Nakatani

    Nucleic Acids and Molecular Biology p. 189-207 2016/04/05 Part of collection (book)

    Publisher: Springer International Publishing
  59. Exploratory Study on the RNA-Binding Structural Motifs by Library Screening Targeting pre-miRNA-29a

    Takeo Fukuzumi, Asako Murata, Haruo Aikawa, Yasue Harada, Kazuhiko Nakatani

    CHEMISTRY-A EUROPEAN JOURNAL Vol. 21 No. 47 p. 16859-16867 2015/11 Research paper (scientific journal)

  60. 2-Aminophenanthroline dimer stabilized the C-C mismatched duplex DNA

    Jinxing Li, Jun Matsumoto, Takahiro Otabe, Chikara Dohno, Kazuhiko Nakatani

    BIOORGANIC & MEDICINAL CHEMISTRY Vol. 23 No. 4 p. 753-758 2015/02 Research paper (scientific journal)

  61. Recognition of Chelerythrine to Human Telomeric DNA and RNA G-quadruplexes

    Li-Ping Bai, Masaki Hagihara, Kazuhiko Nakatani, Zhi-Hong Jiang

    SCIENTIFIC REPORTS Vol. 4 2014/10 Research paper (scientific journal)

  62. Modulation of binding properties of amphiphilic DNA containing multiple dodecyl phosphotriester linkages to lipid bilayer membrane

    Shingo Makishi, Tomonori Shibata, Masatsugu Okazaki, Chikara Dohno, Kazuhiko Nakatani

    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS Vol. 24 No. 15 p. 3578-3581 2014/08 Research paper (scientific journal)

  63. The Chemistry of Polymerase Chain Reaction-Development of the PCR Method Using New Modified Primers

    Fumie Takei, Kazuhiko Nakatani

    JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN Vol. 72 No. 4 p. 370-381 2014/04 Research paper (scientific journal)

  64. Formation of a Ligand- Assisted Complex of Two RNA Hairpin Loops

    Changfeng Hong, Takahiro Otabe, Saki Matsumoto, Chikara Dohno, Asako Murata, Masaki Hagihara, Kazuhiko Nakatani

    CHEMISTRY-A EUROPEAN JOURNAL Vol. 20 No. 18 p. 5282-5287 2014/04 Research paper (scientific journal)

  65. Detection of hepatitis C virus by single-step hairpin primer RT-PCR

    Fumie Takei, Hideki Tani, Yoshiharu Matsuura, Kazuhiko Nakatani

    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS Vol. 24 No. 1 p. 394-396 2014/01 Research paper (scientific journal)

  66. Development of photoswitchable RNA aptamer-ligand complexes

    Gosuke Hayashi, Kazuhiko Nakatani

    Methods in Molecular Biology Vol. 1111 p. 29-40 2014 Research paper (scientific journal)

    Publisher: Humana Press Inc.
  67. Facile electrochemical biosensor based on a new bifunctional probe for label-free detection of CGG trinucleotide repeat

    Hanping He, Jingping Xia, Xiaoqian Peng, Gang Chang, Xiuhua Zhang, Yafen Wang, Kazuhiko Nakatani, Zhaowen Lou, Shengfu Wang

    BIOSENSORS & BIOELECTRONICS Vol. 49 p. 282-289 2013/11 Research paper (scientific journal)

  68. Fluorescent indicator displacement assay of ligands targeting 10 microRNA precursors

    Asako Murata, Yasue Harada, Takeo Fukuzumi, Kazuhiko Nakatani

    BIOORGANIC & MEDICINAL CHEMISTRY Vol. 21 No. 22 p. 7101-7106 2013/11 Research paper (scientific journal)

  69. A Synthetic Riboswitch that Operates using a Rationally Designed Ligand-RNA Pair

    Chikara Dohno, Izumi Kohyama, Maki Kimura, Masaki Hagihara, Kazuhiko Nakatani

    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION Vol. 52 No. 38 p. 9976-9979 2013/09 Research paper (scientific journal)

  70. Ligand-inducible formation of RNA pseudoknot

    Saki Matsumoto, Changfeng Hong, Takahiro Otabe, Asako Murata, Kazuhiko Nakatani

    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS Vol. 23 No. 12 p. 3539-3541 2013/06 Research paper (scientific journal)

  71. Selective recognition of G-G mismatch using the double functional probe with electrochemical active ferrocenyl

    Hanping He, Jingping Xia, Gang Chang, Xiaoqian Peng, Zhaowen Lou, Kazuhiko Nakatani, Xiang Zhou, Shengfu Wang

    BIOSENSORS & BIOELECTRONICS Vol. 42 p. 36-40 2013/04 Research paper (scientific journal)

  72. A novel DANP-coupled hairpin RT-PCR for rapid detection of Chikungunya virus

    Huixin Chen, Fumie Takei, Evelyn Siew-Chuan Koay, Kazuhiko Nakatani, Justin Jang Hann Chu

    Journal of Molecular Diagnostics Vol. 15 No. 2 p. 227-233 2013/03 Research paper (scientific journal)

  73. A dimeric form of N-methoxycarbonyl-2-amino-1,8-naphthyridine bound to the A-A mismatch in the CAG/CAG base triad in dsRNA

    Kazuhiko Nakatani, Mariko Toda, Hanping He

    Bioorganic and Medicinal Chemistry Letters Vol. 23 No. 2 p. 558-561 2013/01/15 Research paper (scientific journal)

  74. Xanthone derivatives as potential inhibitors of miRNA processing by human Dicer: Targeting secondary structures of pre-miRNA by small molecules

    Asako Murata, Takeo Fukuzumi, Shiori Umemoto, Kazuhiko Nakatani

    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS Vol. 23 No. 1 p. 252-255 2013/01 Research paper (scientific journal)

  75. Ligand-induced electron spin-assembly on a DNA tile

    Hiroshi Atsumi, Shigeaki Nakazawa, Chikara Dohno, Kazunobu Sato, Takeji Takui, Kazuhiko Nakatani

    CHEMICAL COMMUNICATIONS Vol. 49 No. 57 p. 6370-6372 2013 Research paper (scientific journal)

  76. G-quadruplex formation of entirely hydrophobic DNA in organic solvents

    Tomonori Shibata, Chikara Dohno, Kazuhiko Nakatani

    CHEMICAL COMMUNICATIONS Vol. 49 No. 48 p. 5501-5503 2013 Research paper (scientific journal)

  77. Activation of prokaryotic translation by antisense oligonucleotides binding to coding region of mRNA

    Gosuke Hayashi, Changfeng Hong, Masaki Hagihara, Kazuhiko Nakatani

    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS Vol. 429 No. 1-2 p. 105-110 2012/12 Research paper (scientific journal)

  78. Amphiphilic DNA Duplex Stabilized by a Hydrophobic Zipper

    Chikara Dohno, Tomonori Shibata, Masatsugu Okazaki, Shingo Makishi, Kazuhiko Nakatani

    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY No. 27 p. 5317-5323 2012/09 Research paper (scientific journal)

  79. Structure-Activity Studies on the Fluorescent Indicator in a Displacement Assay for the Screening of Small Molecules Binding to RNA

    Shiori Umemoto, Seongwang Im, Jinhua Zhang, Masaki Hagihara, Asako Murata, Yasue Harada, Takeo Fukuzumi, Takahiro Wazaki, Shin-ichi Sasaoka, Kazuhiko Nakatani

    CHEMISTRY-A EUROPEAN JOURNAL Vol. 18 No. 32 p. 9999-10008 2012/08 Research paper (scientific journal)

  80. Competitive Allele-Specific Hairpin Primer PCR for Extremely High Allele Discrimination in Typing of Single Nucleotide Polymorphisms

    Fumie Takei, Masako Igarashi, Yoshimi Oka, Yusuke Koga, Kazuhiko Nakatani

    CHEMBIOCHEM Vol. 13 No. 10 p. 1409-1412 2012/07 Research paper (scientific journal)

  81. Naphthyridine tetramer with a pre-organized structure for 1:1 binding to a CGG/CGG sequence

    Chikara Dohno, Izumi Kohyama, Changfeng Hong, Kazuhiko Nakatani

    NUCLEIC ACIDS RESEARCH Vol. 40 No. 6 p. 2771-2781 2012/03 Research paper (scientific journal)

  82. A small molecule regulates hairpin structures in d(CGG) trinucleotide repeats

    Masaki Hagihara, Hanping He, Maki Kimura, Kazuhiko Nakatani

    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS Vol. 22 No. 5 p. 2000-2003 2012/03 Research paper (scientific journal)

  83. Tandem Arrays of TEMPO and Nitronyl Nitroxide Radicals with Designed Arrangements on DNA

    Hiroshi Atsumi, Kensuke Maekawa, Shigeaki Nakazawa, Daisuke Shiomi, Kazunobu Sato, Masahiro Kitagawa, Takeji Takui, Kazuhiko Nakatani

    CHEMISTRY-A EUROPEAN JOURNAL Vol. 18 No. 1 p. 178-183 2012/01 Research paper (scientific journal)

  84. Molecular-Glue-Triggered DNA Assembly To Form a Robust and Photoresponsive Nano-Network

    Chunyan Wang, Fang Pu, Youhui Lin, Jinsong Ren, Chikara Dohn, Kazuhiko Nakatani, Xiaogang Qu

    CHEMISTRY-A EUROPEAN JOURNAL Vol. 17 No. 29 p. 8189-8194 2011/07 Research paper (scientific journal)

  85. Small Molecule Modulates Hairpin Structures in CAG Trinucleotide Repeats

    Masaki Hagihara, Hanping He, Kazuhiko Nakatani

    CHEMBIOCHEM Vol. 12 No. 11 p. 1686-1689 2011/07 Research paper (scientific journal)

  86. Ligand inducible assembly of a DNA tetrahedron

    Chikara Dohno, Hiroshi Atsumi, Kazuhiko Nakatani

    CHEMICAL COMMUNICATIONS Vol. 47 No. 12 p. 3499-3501 2011 Research paper (scientific journal)

  87. Ligand-Assisted Complex Formation of Two DNA Hairpin Loops

    Changfeng Hong, Masaki Hagihara, Kazuhiko Nakatani

    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION Vol. 50 No. 19 p. 4390-4393 2011 Research paper (scientific journal)

  88. Control of DNA hybridization by photoswitchable molecular glue

    Chikara Dohno, Kazuhiko Nakatani

    CHEMICAL SOCIETY REVIEWS Vol. 40 No. 12 p. 5718-5729 2011

  89. Antisense-Induced Guanine Quadruplexes Inhibit Reverse Transcription by HIV-1 Reverse Transcriptase

    Masaki Hagihara, Lisa Yamauchi, Akiko Seo, Keisuke Yoneda, Mayo Senda, Kazuhiko Nakatani

    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY Vol. 132 No. 32 p. 11171-11178 2010/08 Research paper (scientific journal)

  90. Discrimination of N6-methyl adenine in a specific DNA sequence

    Chikara Dohno, Tomonori Shibata, Kazuhiko Nakatani

    CHEMICAL COMMUNICATIONS Vol. 46 No. 30 p. 5530-5532 2010 Research paper (scientific journal)

  91. Development of molecules binding to mismatched base pairs: Application to the detection of gene mutation and PCR monitoring

    Kazuhiko Nakatani

    Seikagaku Vol. 82 No. 7 p. 646-651 2010 Research paper (scientific journal)

  92. Ligand Binding to Tandem G Quadruplexes from Human Telomeric DNA

    Li-Ping Bai, Masaki Hagihara, Zhi-Hong Jiang, Kazuhiko Nakatani

    CHEMBIOCHEM Vol. 9 No. 16 p. 2583-2587 2008/11 Research paper (scientific journal)

  93. The crystallographic study of left-handed Z-DNA d(CGCGCG)(2) and thermine complexes crystallized at various temperatures and at various concentration of cations

    Hirofumi Ohishi, Mamiko Odoko, Da-Yang Zhou, Yoshitaka Tozuka, Nobuo Okabe, Kazuhiko Nakatani, Toshimasa Ishida, Kazmierz Grzeskowlak

    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS Vol. 368 No. 2 p. 382-387 2008/04 Research paper (scientific journal)

  94. Polyamines stabilize left-handed Z-DNA: Using X-ray crystallographic analysis, we have found a new type of polyamine (PA) that stabilizes left-handed Z-DNA

    Hirofumi Ohishi, Mamiko Odoko, Kazimierz Grzeskowiak, Yoichi Hiyama, Koji Tsukamoto, Naoyoshi Maezaki, Toshimasa Ishida, Tetsuaki Tanaka, Nobuo Okabe, Keiichi Fukuyama, Da-Yang Zhou, Kazuhiko Nakatani

    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS Vol. 366 No. 2 p. 275-280 2008/02 Research paper (scientific journal)

  95. Evaluation of mismatch-binding ligands as inhibitors for Rev-RRE interaction

    Kazuhiko Nakatani, Souta Horie, Yuki Goto, Akio Kobori, Shinya Hagihara

    BIOORGANIC & MEDICINAL CHEMISTRY Vol. 14 No. 15 p. 5384-5388 2006/08 Research paper (scientific journal)

  96. Control of DNA hybridization by photoswitchable mismatch binding ligands.

    Dohno C, Uno SN, Nakatani K

    Nucleic acids symposium series (2004) No. 50 p. 87-88 2006

  97. Inhibition of DNA replication by a d(CAG) repeat binding ligand.

    Hagihara M, Nakatani K

    Nucleic acids symposium series (2004) No. 50 p. 147-148 2006

  98. Measurement of circular dichroism and structural chemical research of d(CG)6 and d(TA)6.

    Tozuka Y, Yoshikawa Y, Ohishi H, Kobayashi Y, Da-Yang Z, Nakatani K

    Nucleic acids symposium series (2004) No. 50 p. 227-228 2006

  99. N,N '-Bis(3-aminopropyl)-2,7-diamino-1,8-naphthyridine stabilized a single pyrimidine bulge in duplex DNA

    H Suda, A Kobori, JH Zhang, G Hayashi, K Nakatani

    BIOORGANIC & MEDICINAL CHEMISTRY Vol. 13 No. 14 p. 4507-4512 2005/07 Research paper (scientific journal)

  100. 2P137 NMR structural analysis of the CGG/CGG containing DNA complexed with the recognition drugs

    Nomura M., Hagihara S., Goto Y., Nakatani K., Kojima C.

    Seibutsu Butsuri Vol. 45 2005

    Publisher: The Biophysical Society of Japan General Incorporated Association
  101. A new ligand binding to G-G mismatch having improved thermal and alkaline stability

    T Peng, T Murase, Y Goto, A Kobori, K Nakatani

    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS Vol. 15 No. 2 p. 259-262 2005/01 Research paper (scientific journal)

  102. Binding of naphthyridine carbamate dimer to the (CGG)(n) repeat results in the disruption of the G-C base pairing

    T Peng, K Nakatani

    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION Vol. 44 No. 44 p. 7280-7283 2005 Research paper (scientific journal)

  103. Molecular labeling of the CGG trinucleotide repeat.

    Peng T, Nakatani K

    Nucleic acids symposium series (2004) No. 49 p. 39-40 2005

  104. Solution structure of a small-molecular ligand complexed with CAG trinucleotide repeat DNA.

    Nakatani K, Hagihara S, Goto Y, Kobori A, Hagihara M, Hayashi G, Kyo M, Nomura M, Mishima M, Kojima C

    Nucleic acids symposium series (2004) No. 49 p. 49-50 2005 Research paper (scientific journal)

  105. NMR structural analysis of the G.G mismatch DNA complexed with naphthyridine-dimer.

    Nomura M, Hagihara S, Goto Y, Nakatani K, Kojima C

    Nucleic acids symposium series (2004) No. 49 p. 213-214 2005 Research paper (scientific journal)

  106. Application of L-DNA as a molecular tag.

    Hayashi G, Hagihara M, Nakatani K

    Nucleic acids symposium series (2004) No. 49 p. 261-262 2005

  107. Chemistry challenges in SNP typing

    K Nakatani

    CHEMBIOCHEM Vol. 5 No. 12 p. 1623-1633 2004/12

  108. 2-Ureidoquinoline: a useful molecular element for stabilizing single cytosine and thymine bulges

    A Kobori, T Murase, H Suda, Saito, I, K Nakatani

    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS Vol. 14 No. 13 p. 3431-3433 2004/07 Research paper (scientific journal)

  109. The binding of guanine-guanine mismatched DNA to naphthyridine dimer immobilized sensor surfaces: kinetic aspects

    K Nakatani, A Kobori, H Kumasawa, Y Goto, Saito, I

    BIOORGANIC & MEDICINAL CHEMISTRY Vol. 12 No. 12 p. 3117-3123 2004/06 Research paper (scientific journal)

  110. Highly sensitive detection of GG mismatched DNA by surfaces immobilized naphthyridine dimer through poly(ethylene oxide) linkers

    K Nakatani, A Kobori, H Kumasawa, Saito, I

    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS Vol. 14 No. 5 p. 1105-1108 2004/03 Research paper (scientific journal)

  111. Detection of guanine-adenine mismatches by surface plasmon resonance sensor carrying naphthyridine-azaquinolone hybrid on the surface

    S Hagihara, H Kumasawa, Y Goto, G Hayashi, A Kobori, Saito, I, K Nakatani

    NUCLEIC ACIDS RESEARCH Vol. 32 No. 1 p. 278-286 2004/01 Research paper (scientific journal)

  112. The SPR sensor detecting cytosine-cytosine mismatches

    A Kobori, S Horie, H Suda, Saito, I, K Nakatani

    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY Vol. 126 No. 2 p. 557-562 2004/01 Research paper (scientific journal)

  113. Separation of mismatched DNA by using the affinity column immobilizing mismatch-binding ligands.

    Goto Y, Kobori A, Suda H, Nakatani K

    Nucleic acids symposium series (2004) No. 48 p. 123-124 2004 Research paper (scientific journal)

  114. SPR fingerprinting of mismatched base pair.

    Kobori A, Peng T, Hayashi G, Nakatani K

    Nucleic acids symposium series (2004) No. 48 p. 129-130 2004 Research paper (scientific journal)

  115. Hole trapping at N-6-cyclopropyideoxyadenosine suggests a direct contribution of adenine bases to hole transport through DNA

    C Dohno, A Ogawa, K Nakatani, Saito, I

    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY Vol. 125 No. 34 p. 10154-10155 2003/08 Research paper (scientific journal)

  116. Affinity labeling of a single guanine bulge

    K Nakatani, S Horie, Saito, I

    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY Vol. 125 No. 30 p. 8972-8973 2003/07 Research paper (scientific journal)

  117. Assessment of the sequence dependency for the binding of 2-aminonaphthyridine to the guanine bulge

    K Nakatani, S Horie, T Murase, S Hagihara, Saito, I

    BIOORGANIC & MEDICINAL CHEMISTRY Vol. 11 No. 10 p. 2347-2353 2003/05 Research paper (scientific journal)

  118. Formation and destruction of the guanine quartet in solution observed by cold-spray ionization mass spectrometry.

    Sakamoto S, Nakatani K, Saito I, Yamaguchi K

    Chemical communications (Cambridge, England) No. 6 p. 788-789 2003/03

  119. Induction of a remarkable conformational change in a human telomeric sequence by the binding of naphthyridine dimer: Inhibition of the elongation of a telomeric repeat by telomerase

    K Nakatani, S Hagihara, S Sando, S Sakamoto, K Yamaguchi, C Maesawa, Saito, I

    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY Vol. 125 No. 3 p. 662-666 2003/01 Research paper (scientific journal)

  120. Detection of the C-C mismatched base pair by small ligands.

    Kobori A, Suda H, Nakatani K, Saito I

    Nucleic acids research. Supplement (2001) No. 3 p. 131-132 2003 Research paper (scientific journal)

  121. The binding of naphthyridine tetramer to guanine-rich sequences.

    Goto Y, Hagihara S, Kobori A, Nakatani K, Saito I

    Nucleic acids research. Supplement (2001) No. 3 p. 133-134 2003 Research paper (scientific journal)

  122. 2,6-Diaminonaphthyridine derivatives bind to a single nucleotide bulge in DNA.

    Suda H, Hagihara S, Kobori A, Nakatani K, Saito I

    Nucleic acids research. Supplement (2001) No. 3 p. 139-140 2003 Research paper (scientific journal)

  123. Guanine of the third strand of C·G*G triplex serves as an effective hole trap

    Chikara Dohno, Kazuhiko Nakatani, Isao Saito

    Journal of the American Chemical Society Vol. 124 No. 49 p. 14580-14585 2002/12/11 Research paper (scientific journal)

  124. N(2)-phenyldeoxyguanosine: modulation of the chemical properties of deoxyguanosine toward one-electron oxidation in DNA.

    Nakatani K, Dohno C, Saito I

    Journal of the American Chemical Society Vol. 124 No. 24 p. 6802-6803 2002/06

  125. Chemically induced hairpin formation in DNA monolayers

    EA Smith, M Kyo, H Kumasawa, K Nakatani, Saito, I, RM Corn

    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY Vol. 124 No. 24 p. 6810-6811 2002/06 Research paper (scientific journal)

  126. Photochemistry of benzophenone immobilized in a major groove of DNA: formation of thermally reversible interstrand cross-link.

    Nakatani K, Yoshida T, Saito I

    Journal of the American Chemical Society Vol. 124 No. 10 p. 2118-2119 2002/03

  127. Suppression of DNA-mediated charge transport by BamHI binding

    K Nakatani, C Dohno, A Ogawa, Saito, I

    CHEMISTRY & BIOLOGY Vol. 9 No. 3 p. 361-366 2002/03 Research paper (scientific journal)

  128. Recognition of DNA mismatch structures.

    Hagihara S, Nakatani K, Saito I

    Nucleic acids research. Supplement (2001) No. 2 p. 127-128 2002

  129. Binding analysis between naphthyridine dimers and GG mismatch DNA.

    Kobori A, Kumasawa H, Nakatani K, Saito I

    Nucleic acids research. Supplement (2001) No. 2 p. 185-186 2002 Research paper (scientific journal)

  130. Synthesis of an ABC Ring Analogue of Kapurimycin A3 as an Effective DNA Alkylating Agent

    Kazuhiko Nakatani, Akimitsu Okamoto, Isao Saito

    Angewandte Chemie (International Edition in English) Vol. 36 No. 24 p. 2794-2797 1997 Research paper (scientific journal)

    Publisher: Wiley-VCH Verlag
  131. New Aspects of α-Diazocarbonyl Compounds From Construction of the Novel Carbon Framework to the Photoinduced DNA Cleavage

    NAKATANI Kazuhiko

    J. Synth. Org. Chem. Jpn. Vol. 53 No. 12 p. 1068-1076 1995/12/01

    Publisher: The Society of Synthetic Organic Chemistry, Japan
  132. Synthesis of Asperuloside Aglucon Silyl Ether and Garjasmine from (+)-Genipin via Gardenoside Aglucon Disilyl Ether as a Common Intermediate

    NAKATANI Kazuhiko, HIRAISHI Atsushi, HAN Qingjun, ISOE Sachihiko

    Chemistry Letters Vol. 1992 No. 9 p. 1851-1854 1992/09/05

    Publisher: The Chemical Society of Japan

Misc. 146

  1. 7位修飾ナフチリジンカルバメートダイマーの合成と結合特性

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    日本化学会春季年会講演予稿集(CD-ROM) Vol. 99th 2019

  2. RNA切断活性をもつミスマッチ結合性リガンドの開発

    三木翔太, 三木翔太, 山田剛史, 中谷和彦

    日本化学会春季年会講演予稿集(CD-ROM) Vol. 97th 2017

  3. Cover Picture: A Ligand That Targets CUG Trinucleotide Repeats (Chem. Eur. J. 42/2016)

    Jinxing Li, Jun Matsumoto, Li-Ping Bai, Asako Murata, Chikara Dohno, Kazuhiko Nakatani

    Chemistry - A European Journal Vol. 22 No. 42 2016/10/10 Rapid communication, short report, research note, etc. (scientific journal)

    Publisher: Wiley-VCH Verlag
  4. The Chemistry of PCR Primers: Concept and Application

    Fumie Takei, Kazuhiko Nakatani

    ISRAEL JOURNAL OF CHEMISTRY Vol. 53 No. 6-7 p. 401-416 2013/06 Book review, literature introduction, etc.

  5. RNAバルジ結合性小分子の合成とDicer切断反応の阻害剤としての利用

    小田部尭広, 村田亜沙子, 武井史恵, 中谷和彦

    日本化学会講演予稿集 Vol. 93rd No. 3 2013

  6. Noncovalent Assembly of TEMPO Radicals Pair-wise Embedded on a DNA Duplex

    Hiroshi Atsumi, Kensuke Maekawa, Shigeaki Nakazawa, Daisuke Shiomi, Kazunobu Sato, Masahiro Kitagawa, Takeji Takui, Kazuhiko Nakatani

    CHEMISTRY LETTERS Vol. 39 No. 6 p. 556-557 2010/06

  7. A reverse transcriptase stop assay revealed diverse quadruplex formations in UTRs in mRNA

    Masaki Hagihara, Keisuke Yoneda, Hiroaki Yabuuchi, Yasushi Okuno, Kazuhiko Nakatani

    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS Vol. 20 No. 7 p. 2350-2353 2010/04

  8. Fluorescent Indicator Displacement Assay for Ligand-RNA Interactions

    Jinhua Zhang, Shiori Umemoto, Kazuhiko Nakatani

    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY Vol. 132 No. 11 p. 3660-+ 2010/03

  9. Transformation of cytosine to uracil in single-stranded DNA via their oxime sulfonates

    Oka Yoshimi, Takei Fumie, Nakatani Kazuhiko

    Abstracts of Papers: Host-Guest Chemistry Symposium Vol. 2010 p. 63-63 2010

    Publisher: Association of Research for Host-Guest and Supramolecular Chemistry
  10. DNA crosslink tonatural base by a formyl group-containing DNA

    2010

  11. The Development of The Displacement Assay, Screening Method for Detecting the RNA-ligand Interactions (2)

    2010

  12. Spin labeling of DNA by using radical-containing mismatch binding ligands

    2010

  13. The motion between (CGG)n containing hairpin DNA and G-G mismatch binding molecule

    2010

  14. The Development of The Displacement Assay, Screening Method for Detecting the RNA-ligand Interactions (2)

    2010

  15. The motion between (CGG)n containing hairpin DNA and G-G mismatch binding molecule

    2010

  16. Spin labeling of DNA by using radical-containing mismatch binding ligands

    2010

  17. DNA crosslink tonatural base by a formyl group-containing DNA

    2010

  18. Programmed assembly of organic radicals on DNA

    Kensuke Maekawa, Shigeaki Nakazawa, Hiroshi Atsumi, Daisuke Shiomi, Kazunobu Sato, Masahiro Kitagawa, Takeji Takui, Kazuhiko Nakatani

    CHEMICAL COMMUNICATIONS Vol. 46 No. 8 p. 1247-1249 2010

  19. Transformation of cytosine to uracil in single-stranded DNA via their oxime sulfonates

    Yoshimi Oka, Fumie Takei, Kazuhiko Nakatani

    CHEMICAL COMMUNICATIONS Vol. 46 No. 19 p. 3378-3380 2010

  20. Secondary-structure-inducible ligand fluorescence coupled with PCR

    Fumie Takei, Masako Igarashi, Masaki Hagihara, Yoshimi Oka, Yoshihiro Soya, Kazuhiko Nakatani

    Angewandte Chemie - International Edition Vol. 48 No. 42 p. 7822-7824 2009/10/05

  21. Recognition of Mismatched Base Pairs in DNA

    Kazuhiko Nakatani

    BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN Vol. 82 No. 9 p. 1055-1069 2009/09

  22. Photoswitchable Unsymmetrical Ligand for DNA Hetero-Mismatches

    Chikara Dohno, Tsuyoshi Yamamoto, Kazuhiko Nakatani

    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY Vol. - 4051-4058 No. 24 p. 4051-4058 2009/08

  23. Synthesis and Reaction of DNA Oligomers Containing Modified Cytosines Related to Bisulfite Sequencing

    Yoshimi Oka, Tao Peng, Fumie Takei, Kazuhiko Nakatani

    ORGANIC LETTERS Vol. 11 No. 6 p. 1377-1379 2009/03

  24. The effect of linker length on binding affinity of a photoswitchable molecular glue for DNA

    Chikara Dohno, Shin-Nosuke Uno, Shun Sakai, Mika Oku, Kazuhiko Nakatani

    BIOORGANIC & MEDICINAL CHEMISTRY Vol. 17 No. 6 p. 2536-2543 2009/03

  25. DNA cross-link generated by a novel modified DNA containing a formyl group

    2009

  26. DNA cross-linking that is targeted to amino group in natural base

    2009

  27. In vitro selection of RNA aptamers that can bind to synthetic GFP chromophore analogues

    2009

  28. Recognition of Mismatched base pairs in DNA

    Kazuhiko Nakatani

    Bulletin of the Chemical Society of Japan Vol. 82 No. 9 p. 1055-1069 2009

  29. Reaction of cytosine with bisulfite and hydroxylamine.

    2009

  30. Integrated Polymerase Chain Reaction (PCR) by Novel Chemical labeling

    2009

  31. DNA-Labeling by Secondary Structure Inducible Ligand Fluorescence

    2009

  32. Light-Driven Light-Switching DNA Device

    2009

  33. The Development of The Displacement Assay, Screening Method for Detecting the RNA-ligand Interactions

    2009

  34. Synthesis and Reaction of DNA Oligomers Containing Modified Cytosines Related to Bisulfite Sequencing

    Org. Lett. Vol. 11 1377-1379 2009

  35. A Small Molecule Affecting the Replication of Trinucleotide Repeat d(GAA)(n)

    Hanping He, Masaki Hagihara, Kazuhiko Nakatani

    CHEMISTRY-A EUROPEAN JOURNAL Vol. 15 No. 40 p. 10641-10648 2009

  36. Photoswitchable Unsymmetrical Ligand for DNA Hetero-Mismatches

    Eur. J. Org. Chem. Vol. - 4051-4058 2009

  37. Synthesis and Reaction of DNA Oligomers Containing Modified Cytosines Related to Bisulfite Sequencing

    Org. Lett. Vol. 11 1377-1379 2009

  38. In vitro selection of RNA aptamers that can bind to synthetic GFP chromophore analogues

    2009

  39. Secondary-Structure-Inducible Ligand Fluorescence Coupled with PCR

    Fumie Takei, Masako Igarashi, Masaki Hagihara, Yoshimi Oka, Yoshihiro Soya, Kazuhiko Nakatani

    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION Vol. 48 No. 42 p. 7822-7824 2009

  40. A Light-Driven Supramolecular Optical Switch

    Shin-nosuke Uno, Chikara Dohno, Holger Bittermann, Vladimir L. Malinovskii, Robert Haener, Kazuhiko Nakatani

    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION Vol. 48 No. 40 p. 7362-7365 2009

  41. DNA cross-link generated by a novel modified DNA containing a formyl group

    2009

  42. Reaction of cytosine with bisulfite and hydroxylamine.

    2009

  43. DNA cross-linking that is targeted to amino group in natural base

    2009

  44. Integrated Polymerase Chain Reaction (PCR) by Novel Chemical labeling

    2009

  45. Light-Driven Light-Switching DNA Device

    2009

  46. DNA-Labeling by Secondary Structure Inducible Ligand Fluorescence

    2009

  47. The Development of The Displacement Assay, Screening Method for Detecting the RNA-ligand Interactions

    2009

  48. RNA Aptamers That Reversibly Bind Photoresponsive Azobenzene-Containing Peptides

    Gosuke Hayashi, Masaki Hagihara, Kazuhiko Nakatani

    CHEMISTRY-A EUROPEAN JOURNAL Vol. 15 No. 2 p. 424-432 2009

  49. Dimer of 2,7-diamino-1,8-naphthyridine for the detection of mismatches formed by pyrimidine nucleotide bases

    Akio Kobori, Kazuhiko Nakatani

    BIOORGANIC & MEDICINAL CHEMISTRY Vol. 16 No. 24 p. 10338-10344 2008/12

  50. Site-specific binding of chelerythrine and sanguinarine to single pyrimidine bulges in hairpin DNA

    Li-Ping Bai, Zongwei Cai, Zhong-Zhen Zhao, Kazuhiko Nakatani, Zhi-Hong Jiang

    ANALYTICAL AND BIOANALYTICAL CHEMISTRY Vol. 392 No. 4 p. 709-716 2008/10

  51. DNA labeling by ligand inducible secondary structure

    Tao Peng, Hanping He, Masaki Hagihara, Kazuhiko Nalkatani

    CHEMBIOCHEM Vol. 9 No. 12 p. 1893-1897 2008/08

  52. Genotyping by allele-specific L-DNA-tagged PCR

    Gosuke Hayashi, Masaki Hagihara, Kazuhiko Nakatani

    JOURNAL OF BIOTECHNOLOGY Vol. 135 No. 2 p. 157-160 2008/06

  53. Ligand-stabilized hairpin structures interfere with elongation of human telomere

    Masaki Hagihara, Yuki Goto, Kazuhiko Nakatani

    CHEMBIOCHEM Vol. 9 No. 4 p. 510-513 2008/03

  54. Ligand Binding to Tandem G-quadruplex from Human Telomeric DNA

    ChemBioChem Vol. 9 2583-2587 2008

  55. Synthesis of Dimeric 2-Amino-1,8-naphthyridine and Related DNA-Binding Molecules

    Current Protocols in Nucleic Acid Chemistry Vol. 2 1-21 2008

  56. Small molecule affecting the synthesis of trinucleotide Repeat (GAA)n

    2008

  57. Preparation and evaluation of small molecule binding to trinucleotide repeat d(GAA)n

    2008

  58. Synthesis and evaluation of photoresponsive molecular Glue for DNA

    2008

  59. THE FLUORESCENT DETECTION OF SINGLE NUCLEOTIDE DIFFERENCE USING CYTOSINE BULGE HAIRPIN PRIMERS

    2008

  60. Fluorescent Ligand as a molecular probe for the RNA structure

    2008

  61. The reaction of cytosine with bisulfite by base flipping from the duplex

    2008

  62. Reversible control of DNA hybridization by a small synthetic ligand

    2008

  63. RNA aptamers that reversibly bind to photoresponsive peptide

    2008

  64. Application for the Fluorescent Detection of Single Nucleotide Difference using Cytosine Bulge Hairpin Primers

    2008

  65. Switching DNA hybridization by a molecular glue for DNA

    2008

  66. Displacement Assay For RNA-ligand Interactions, Using Ligand's Fluorescent Property

    2008

  67. Photoswitchable Control of Binding between a Photoresponsive Peptide and the RNA Aptamers

    2008

  68. Synthesis of dimeric 2-amino-1,8-naphthyridine and related DNA-binding molecules

    Curr. Protoc. Nucleic Acid Chem. Vol. Chapter 8 Unit 8.6 2008

  69. Molecular Glue for DNA

    2008

  70. Ligand Binding to Tandem G-quadruplex from Human Telomeric DNA

    ChemBioChem Vol. 9 2583-2587 2008

  71. Synthesis of Dimeric 2-Amino-1,8-naphthyridine and Related DNA-Binding Molecules

    Current Protocols in Nucleic Acid Chemistry Vol. 2 1-21 2008

  72. Preparation and evaluation of small molecule binding to trinucleotide repeat d(GAA)n

    2008

  73. Small molecule affecting the synthesis of trinucleotide Repeat (GAA)n

    2008

  74. Synthesis and evaluation of photoresponsive molecular Glue for DNA

    2008

  75. THE FLUORESCENT DETECTION OF SINGLE NUCLEOTIDE DIFFERENCE USING CYTOSINE BULGE HAIRPIN PRIMERS

    2008

  76. Fluorescent Ligand as a molecular probe for the RNA structure

    2008

  77. The reaction of cytosine with bisulfite by base flipping from the duplex

    2008

  78. Reversible control of DNA hybridization by a small synthetic ligand

    2008

  79. RNA aptamers that reversibly bind to photoresponsive peptide

    2008

  80. Application for the Fluorescent Detection of Single Nucleotide Difference using Cytosine Bulge Hairpin Primers

    2008

  81. Switching DNA hybridization by a molecular glue for DNA

    2008

  82. Displacement Assay For RNA-ligand Interactions, Using Ligand's Fluorescent Property

    2008

  83. Photoswitchable Control of Binding between a Photoresponsive Peptide and the RNA Aptamers

    2008

  84. Synthesis of dimeric 2-amino-1,8-naphthyridine and related DNA-binding molecules

    Curr. Protoc. Nucleic Acid Chem. Vol. Chapter 8 Unit 8.6 2008

  85. Molecular Glue for DNA

    2008

  86. Photoswitchable molecular glue for DNA

    Chikara Dohno, Shin-Nosuke Uno, Kazuhiko Nakatani

    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY Vol. 129 No. 39 p. 11898-+ 2007/10

  87. Photoregulation of a peptide-RNA interaction on a gold surface

    Gosuke Hayashi, Masaki Hagihara, Chikara Dohno, Kazuhiko Nakatani

    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY Vol. 129 No. 28 p. 8678-+ 2007/07

  88. Emission of characteristic fluorescence from the ligand-cytosine complex in U_A/ACU bulged RNA duplex

    Jinhua Zhang, Fumie Takei, Kazuhiko Nakatani

    BIOORGANIC & MEDICINAL CHEMISTRY Vol. 15 No. 14 p. 4813-4817 2007/07

  89. Analysis of mismatched DNA by mismatch binding ligand (MBL)-Sepharose affinity chromatography

    Yuki Goto, Hitoshi Suda, Akio Kobori, Kazuhiko Nakatani

    ANALYTICAL AND BIOANALYTICAL CHEMISTRY Vol. 388 No. 5-6 p. 1165-1173 2007/07

  90. Small-molecule binding to the nonquadruplex form of the human telomeric sequence

    Yuki Goto, Shinya Hagihara, Masaki Hagihara, Kazuhiko Nakatani

    CHEMBIOCHEM Vol. 8 No. 7 p. 723-726 2007/05

  91. Bidirectional control of gold nanoparticle assembly by turning on and off DNA hybridization with thermally degradable molecular glue

    Tao Peng, Chikara Dohno, Kazuhiko Nakatani

    CHEMBIOCHEM Vol. 8 No. 5 p. 483-485 2007/03

  92. Exploiting small molecule binding to DNA for the detection of single-nucleotide mismatches and their base environment

    Xiaohong Li, Haifeng Song, Kazuhiko Nakatani, Heinz-Bernhard Kraatz

    ANALYTICAL CHEMISTRY Vol. 79 No. 6 p. 2552-2555 2007/03

  93. Bidirectional control of gold nanoparticle assembly by turning on and off DNA hybridization with thermally degradable molecular glue.

    ChemBioChem Vol. 8 483-485 2007

  94. Photoswitchable Mismatch-Binding Ligands Control DNA Hybridization

    2007

  95. Mismatch-Binding Ligands as a Molecular Glue for DNA

    2007

  96. The rare crystallographic structure of d(CGCGCG)(2): the natural spermidine molecule bound to the minor groove of left-handed Z-DNA d(CGCGCG)(2) at 10 degrees C.

    Biochem. Biophys. Res. Commun. Vol. 358 24-28 2007

  97. Molecular Glue for DNA

    2007

  98. Mismatch-Binding Ligands: Chemistry Approach to Genotyping

    2007

  99. Reversible Control of DNA Hybridization by Photoresponsive Ligands

    2007

  100. Reversible regulation of binding between a photoresponsive peptide and its RNA aptamer

    2007

  101. Detection of L-DNA-tagged PCR products by surface plasmon resonance imaging

    Gosuke Hayashi, Masaki Hagihara, Akio Kobori, Kazuhiko Nakatani

    CHEMBIOCHEM Vol. 8 No. 2 p. 169-171 2007/01

  102. Allele specific C-bulge probes with one unique fluorescent molecule discriminate the single nucleotide polymorphism in DNA

    Fumie Takei, Hitoshi Suda, Masaki Hagihara, Jinhua Zhang, Akio Kobori, Kazuhiko Nakatani

    CHEMISTRY-A EUROPEAN JOURNAL Vol. 13 No. 16 p. 4452-4457 2007

  103. Mismatch-Binding Ligands as a Molecular Glue for DNA

    2007

  104. Photoswitchable Mismatch-Binding Ligands Control DNA Hybridization

    2007

  105. The rare crystallographic structure of d(CGCGCG)(2): the natural spermidine molecule bound to the minor groove of left-handed Z-DNA d(CGCGCG)(2) at 10 degrees C.

    Biochem. Biophys. Res. Commun. Vol. 358 24-28 2007

  106. Stepwise functionalization of ribonucleopeptides: Optimization of the response of fluorescent ribonucleopeptide sensors for ATP

    Tetsuya Hasegawa, Masaki Hagihara, Masatora Fukuda, Takashi Morii

    NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS Vol. 26 No. 10-12 p. 1277-1281 2007

  107. Molecular Glue for DNA

    2007

  108. Mismatch-Binding Ligands: Chemistry Approach to Genotyping

    2007

  109. Reversible Control of DNA Hybridization by Photoresponsive Ligands

    2007

  110. Reversible regulation of binding between a photoresponsive peptide and its RNA aptamer

    2007

  111. Application for The Fluorescent Detection of Single Nucleotide Difference using N, N’-bis(3-aminopropyl)-2,7-diamino-1,8-naphthyridine

    武井史恵, 萩原正規, ZHANG Jinhua, 中谷和彦

    日本化学会講演予稿集 Vol. 86th No. 2 2006

  112. Mismatch-binding ligands function as a molecular glue for DNA

    Tao Peng, Chikara Dohno, Kazuhiko Nakatani

    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION Vol. 45 No. 34 p. 5623-5626 2006

  113. Small-molecule ligand induces nucleotide flipping in (CAG)(n) trinucleotide repeats

    K Nakatani, S Hagihara, Y Goto, A Kobori, M Hagihara, G Hayashi, M Kyo, M Nomura, M Mishima, C Kojima

    NATURE CHEMICAL BIOLOGY Vol. 1 No. 1 p. 39-43 2005/06

  114. Induction of Remarkable Conformatinal Change in a Human Telomeric Sequence by the Binding of Naphthyridine Dimer

    Journal of the American Chemical Society Vol. in press 2003

  115. Induction of Remarkable Conformatinal Change in a Human Telomeric Sequence by the Binding of Naphthyridine Dimer

    Journal of the American Chemical Society Vol. in press 2003

  116. Suppression of DNA-Mediated charge-Transport by BanoH1 Binding

    Chemistry & Biology Vol. 9 No. 361 2002

  117. Suppression of DNA-Mediated charge-Transport by BanoH1 Binding

    Chemistry & Biology Vol. 9 No. 361 2002

  118. DNA Mediated Charge Transport

    NAKATANI Kazuhiko, DOHNO Chikara, SAITO Isao

    Photochemistry Vol. 32 No. 3 p. 129-135 2001/12/15

    Publisher: 光化学協会
  119. Scanning of gvanine-gvanine mismatches in DNA by synthetic ligands using surface plasmon Resonance assay.

    Nature Biotechnology Vol. 19 No. 51 2001

  120. Recognition of Guanine-Guaning Mismatches by Dineric Form of 2-amino-1,8-naphthyridine

    Journal of the American Chemical Society Vol. 123 No. 12650 2001

  121. Scanning of gvanine-gvanine mismatches in DNA by synthetic ligands using surface plasmon Resonance assay.

    Nature Biotechnology Vol. 19 No. 51 2001

  122. Recognition of Guanine-Guaning Mismatches by Dineric Form of 2-amino-1,8-naphthyridine

    Journal of the American Chemical Society Vol. 123 No. 12650 2001

  123. Site selective formation of thymine glycol-containing oligodeoxynucleotides by oxidation with osmium tetroxide and bipyridine-tethered oligonucleotide

    K Nakatani, S Hagihara, S Sando, H Miyazaki, K Tanabe, Saito, I

    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY Vol. 122 No. 26 p. 6309-6310 2000/07

  124. Modulation of DNA-mediated hole-transport efficiency by changing superexchange electronic interaction

    K Nakatani, C Dohno, Saito, I

    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY Vol. 122 No. 24 p. 5893-5894 2000/06

  125. Recognition of a single guanine bulge by 2-acylamino-1,8-naphthyridine

    Kazuhiko Nakatani, Shinsuke Sando, Isao Saito

    Journal of the American Chemical Society Vol. 122 No. 10 p. 2172-2177 2000/03/15

  126. Mapping of the HOMO of Duplex DNA, a new Landmark for DNA Properties.

    Journal of the American Chemical Society Vol. 122 2000

  127. Modulation of DNA Mediated Hole Transport Efficiency by Changing Superexchange Electronicinteraction

    Journal of the American Chemical Society Vol. 122 No. 24 p. 5893-5894 2000

  128. Chemistry of sequence-dependent remote guanine oxidation: Photoreaction of duplex DNA containing cyanobenzophenone-substituted uridine [14]

    Kazuhiko Nakatani, Chikara Dohno, Isao Saito

    Journal of the American Chemical Society Vol. 121 No. 46 p. 10854-10855 1999/11/24 Rapid communication, short report, research note, etc. (scientific journal)

  129. Chemistry of sequence-dependent remote guanine oxidation: Photoreaction of duplex DNA containing cyanobenzophenone-substituted uridine

    K Nakatani, C Dohno, Saito, I

    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY Vol. 121 No. 46 p. 10854-10855 1999/11

  130. Tandem cyclizations involving carbene as an intermediate: Photochemical reactions of substituted 1,2-diketones conjugated with ene-yne

    K Nakatani, K Adachi, K Tanabe, Saito, I

    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY Vol. 121 No. 36 p. 8221-8228 1999/09

  131. Water-soluble 2-amino-1,8-naphthyridine as a novel DNA binding photosensitizer for one-electron oxidation of DNA

    K Nakatani, S Sando, K Yoshida, Saito, I

    TETRAHEDRON LETTERS Vol. 40 No. 33 p. 6029-6032 1999/08

  132. Mechanistic studies on photoinduced cross-linking and specific cleavage at guanine by dibenzoyldiazomethane-oligodeoxynucleotide conjugate

    K Nakatani, S Sando, Saito, I

    BIOORGANIC CHEMISTRY Vol. 27 No. 3 p. 227-237 1999/06

  133. Synthesis of DNA Oligomers Containing Modified Uracil Possessing Electron-Accepting Benzophenone Chromophore

    The Journal of Organic Chemistry Vol. 64 1999

  134. Highly selective DNA alkylation at the 5 ' side G of a 5 ' GG3 ' sequence by an aglycon model of pluramycin antibiotics through preferential intercalation into the GG step

    K Nakatani, A Okamoto, T Matsuno, Saito, I

    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY Vol. 120 No. 44 p. 11219-11225 1998/11

  135. Mapping of the Hot Spots for DNA Damage by One-Electron Oxidation : Efficacy of GG Doublets and GGG Triplets as a Trap

    Journal of the American Chemical Society Vol. 120 No. 48 p. 12686-12687 1998

  136. Guanine specific DNA cleavage by photoirradiation of dibenzoyldiazomethane-oligonucleotide conjugates

    K Nakatani, J Shirai, S Sando, Saito, I

    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY Vol. 119 No. 33 p. 7626-7635 1997/08

  137. Novel synthesis of bifurans via furan-forming photocyclization of alpha-diketones conjugated with ene-yne

    K Nakatani, K Tanabe, Saito, I

    TETRAHEDRON LETTERS Vol. 38 No. 7 p. 1207-1210 1997/02

  138. Synthesis of an ABC ring analogue of kapurimycin A(3) as an effective DNA alkylating agent

    K Nakatani, A Okamoto, Saito, I

    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION Vol. 36 No. 24 p. 2794-2797 1997

  139. Design of DNA-cleaving agents

    Saito, I, K Nakatani

    BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN Vol. 69 No. 11 p. 3007-3019 1996/11 Book review, literature introduction, etc.

  140. ALPHA-DIAZO KETONES AS PHOTOCHEMICAL DNA CLEAVERS - A MIMIC FOR THE RADICAL GENERATING-SYSTEM OF NEOCARZINOSTATIN CHROMOPHORE

    K NAKATANI, S MAEKAWA, K TANABE, SAITO, I

    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY Vol. 117 No. 43 p. 10635-10644 1995/11

  141. Photo in duced CNA Cleavage by Designed Molecules with Conjugated Ene-Yne-Ketene Functionalities

    Tetrahedron Letters Vol. 35 No. 4 p. 605-608 1994

  142. Novel Synthesis of trans-Hydroindenones by Thermal Reaction of α, ω-bis(diazo) diketones

    Journal of Chemical Society Chemical Communications Vol. 6,556/, 1993

  143. Novel Stereocontrolled Synthesis of Exocyclic σ-oxovinyltrimethylsilanes A Potential Route for Stereodefined Exocyclic Tetrasubstituted Alkenes

    Journal of Chemical Society Chemical Communications Vol. 17,1365/, 1993

  144. Novel Synthesis of the Chiral Cyclic Dienediyne System Related to Neocartinostatin Chromophore

    Journal of the Chemical Society Chemical Communications Vol. 289 1992

  145. Synthetic studies on the Compounds Related to Neocarzinostatin Chromophore 2. Synthesis of the Open-Chain(E)-and(Z)-Dienediyne Systems and Its Application

    Tetrahedron Vol. 48,3045/, 1992

  146. Synthesis and Cytotoxicity of Enantiomeric Pairs of Duocarmycin A and Its 2-Epimer

    Bioorganic and Medicinal Chemistry Letters Vol. 2,759/, 1992

Institutional Repository 2

Content Published in the University of Osaka Institutional Repository (OUKA)
  1. Structure‐Binding Relationship of 2‐Amino‐1,8‐Naphthyridine Dimers: Role of Linkage Positions on DNA and RNA Recognition

    Das Bimolendu, Kuwahara Satoki, Ishimaru Ryosuke, Murakami Eitaro, Harada Yasue, Nakatani Kazuhiko

    Chemistry – A European Journal Vol. 23 2025/04/10

  2. The heterodimer of 2-amino-1,8-naphthyridine and 3-aminoisoquinoline binds to the CTG/CTG triad via hydrogen bonding

    Sakurabayashi Shuhei, Yamada Takeshi, Nakatani Kazuhiko

    Bioorganic and Medicinal Chemistry Letters Vol. 114 2024/12/01