顔写真

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Kouyama Masako
香山　雅子
Kouyama Masako
香山　雅子
Institutional repository
Center for Infectious Disease Education and Research，Associate Professor
Institutional repository

Research History 8

  1. 2022/10 - Present
    大阪大学感染症総合教育研究拠点　生体応答学チーム　准教授

  2. 2020/03 - 2022/09
    Osaka University　Research Institute for Microbial Diseases

  3. 2012/04 - 2020/02
    Osaka University　Research Institute for Microbial Diseases

  4. 2011/04 - 2012/03
    Osaka University　Research Institute for Microbial Diseases

  5. 2007/09 - 2011/03
    Washington University in St.Louis　Howard Hughes Medical Institute, Department of Immunology　Research specialist

  6. 2004/09 - 2007/08
    Washington University in St.Louis　Howard Hughes Medical Institute, Department of Immunology　Post Doctoral Fellow

  7. 1999/04 - 2004/08
    Tokyo University of Science

  8. 1997/04 - 1999/03
    理化学研究所　基礎特別研究員

Education 3

  1. The University of Tokyo

    1997/03 -

  2. The University of Tokyo

    1994/03 -

  3. Waseda University　School of Science and Engineering

    1992/03 -

Professional Memberships 1

  1. JAPANESE SOCIETY FOR IMMUNOLOGY (JSI)

Research Areas 1

  1. Life sciences / Immunology /

Papers 51

  1. Neoself-antigens are the primary target for autoreactive T cells in human lupus.

    Shunsuke Mori, Masako Kohyama, Yoshiaki Yasumizu, Asa Tada, Kaito Tanzawa, Tatsuya Shishido, Kazuki Kishida, Hui Jin, Masayuki Nishide, Shoji Kawada, Daisuke Motooka, Daisuke Okuzaki, Ryota Naito, Wataru Nakai, Teru Kanda, Takayuki Murata, Chikashi Terao, Koichiro Ohmura, Noriko Arase, Tomohiro Kurosaki, Manabu Fujimoto, Tadahiro Suenaga, Atsushi Kumanogoh, Shimon Sakaguchi, Yoshihiro Ogawa, Hisashi Arase

    Cell　Vol. 187　No. 21　p. 6071-6087　2024/10/17　Research paper (scientific journal)

  2. Positive and negative regulation of the Fcγ receptor-stimulatory activity of RNA-containing immune complexes by RNase.

    Ryota Naito, Koichiro Ohmura, Shuhei Higuchi, Wataru Nakai, Masako Kohyama, Tsuneyo Mimori, Akio Morinobu, Hisashi Arase

    JCI insight　Vol. 8　No. 16　2023/07/11　Research paper (scientific journal)

  3. SARS-CoV-2 ORF8 is a viral cytokine regulating immune responses.

    Masako Kohyama, Tatsuya Suzuki, Wataru Nakai, Chikako Ono, Sumiko Matsuoka, Koichi Iwatani, Yafei Liu, Yusuke Sakai, Atsushi Nakagawa, Keisuke Tomii, Koichiro Ohmura, Masato Okada, Yoshiharu Matsuura, Shiro Ohshima, Yusuke Maeda, Toru Okamoto, Hisashi Arase

    International immunology　Vol. 35　No. 1　p. 43-52　2023/01/21　Research paper (scientific journal)

  4. Abrogation of self-tolerance by misfolded self-antigens complexed with MHC class II molecules.

    Hui Jin, Kazuki Kishida, Noriko Arase, Sumiko Matsuoka, Wataru Nakai, Masako Kohyama, Tadahiro Suenaga, Ken Yamamoto, Takehiko Sasazuki, Hisashi Arase

    Science advances　Vol. 8　No. 9　2022/03/04　Research paper (scientific journal)

  5. Anti-Double-Stranded DNA Antibodies Recognize DNA Presented on HLA Class II Molecules of Systemic Lupus Erythematosus Risk Alleles.

    Hideaki Tsuji, Koichiro Ohmura, Hui Jin, Ryota Naito, Noriko Arase, Masako Kohyama, Tadahiro Suenaga, Shuhei Sakakibara, Yuta Kochi, Yukinori Okada, Kazuhiko Yamamoto, Hitoshi Kikutani, Akio Morinobu, Tsuneyo Mimori, Hisashi Arase

    Arthritis & rheumatology (Hoboken, N.J.)　Vol. 74　No. 1　p. 105-111　2022/01/01　Research paper (scientific journal)

    Publisher: Wiley

  6. The SARS-CoV-2 Delta variant is poised to acquire complete resistance to wild-type spike vaccines

    Yafei Liu, Noriko Arase, Jun-ichi Kishikawa, Mika Hirose, Songling Li, Asa Tada, Sumiko Matsuoka, Akemi Arakawa, Kanako Akamatsu, Chikako Ono, Hui Jin, Kazuki Kishida, Wataru Nakai, Masako Kohyama, Atsushi Nakagawa, Yoshiaki Yamagishi, Hironori Nakagami, Atsushi Kumanogoh, Yoshiharu Matsuura, Daron M. Standley, Takayuki Kato, Masato Okada, Manabu Fujimoto, Hisashi Arase

    biorxiv　2021/08/23　Research paper (scientific journal)

    Publisher: Cold Spring Harbor Laboratory

  7. An infectivity-enhancing site on the SARS-CoV-2 spike protein targeted by antibodies

    Yafei Liu, Wai Tuck Soh, Jun ichi Kishikawa, Mika Hirose, Emi E. Nakayama, Songling Li, Miwa Sasai, Tatsuya Suzuki, Asa Tada, Akemi Arakawa, Sumiko Matsuoka, Kanako Akamatsu, Makoto Matsuda, Chikako Ono, Shiho Torii, Kazuki Kishida, Hui Jin, Wataru Nakai, Noriko Arase, Atsushi Nakagawa, Maki Matsumoto, Yukoh Nakazaki, Yasuhiro Shindo, Masako Kohyama, Keisuke Tomii, Koichiro Ohmura, Shiro Ohshima, Toru Okamoto, Masahiro Yamamoto, Hironori Nakagami, Yoshiharu Matsuura, Takayuki Kato, Masato Okada, Daron M. Standley, Tatsuo Shioda, Hisashi Arase

    Cell　Vol. 184　No. 13　p. 3452-3.47E+21　2021/06/24　Research paper (scientific journal)

  8. Plasmodium falciparum RIFIN is a novel ligand for inhibitory immune receptor LILRB2

    Akihito Sakoguchi, Fumiji Saito, Kouyuki Hirayasu, Kyoko Shida, Sumiko Matsuoka, Sawako Itagaki, Wataru Nakai, Masako Kohyama, Tadahiro Suenaga, Shiroh Iwanaga, Toshihiro Horii, Hisashi Arase

    Biochemical and Biophysical Research Communications　Vol. 548　p. 167-173　2021/04　Research paper (scientific journal)

  9. A TCR-like antibody against a proinsulin-containing fusion peptide ameliorates type 1 diabetes in NOD mice

    Yushi Matsumoto, Kazuki Kishida, Maki Matsumoto, Sumiko Matsuoka, Masako Kohyama, Tadahiro Suenaga, Hisashi Arase

    Biochemical and Biophysical Research Communications　Vol. 534　p. 680-686　2021/01/01　Research paper (scientific journal)

  10. RAG-Mediated DNA Breaks Attenuate PU.1 Activity in Early B Cells through Activation of a SPIC-BCLAF1 Complex

    Deepti Soodgupta, Lynn S. White, Wei Yang, Rachel Johnston, Jared M. Andrews, Masako Kohyama, Kenneth M. Murphy, Nima Mosammaparast, Jacqueline E. Payton, Jeffrey J. Bednarski

    Cell Reports　Vol. 29　No. 4　p. 829-843.e5　2019/10/22　Research paper (scientific journal)

  11. FcγRIIIA-mediated activation of NK cells by IgG heavy chain complexed with MHC class II molecules

    Yuta Shimizu, Masako Kohyama, Hideki Yorifuji, Hui Jin, Noriko Arase, Tadahiro Suenaga, Hisashi Arase

    International Immunology　Vol. 31　No. 5　p. 303-314　2019/04　Research paper (scientific journal)

  12. Transport of cellular misfolded proteins to the cell surface by HLA-B27 free heavy chain

    Hideki Yorifuji, Noriko Arase, Masako Kohyama, Toru Hirano, Tadahiro Suenaga, Atsushi Kumanogoh, Hisashi Arase

    Biochemical and Biophysical Research Communications　Vol. 511　No. 4　p. 862-868　2019/04　Research paper (scientific journal)

  13. Invariant chain p41 mediates production of soluble MHC class II molecules

    Tatsuya Shishido, Masako Kohyama, Wataru Nakai, Maki Matsumoto, Haruhiko Miyata, Tadahiro Suenaga, Hisashi Arase

    Biochemical and Biophysical Research Communications　Vol. 509　No. 1　p. 216-221　2019/01/29　Research paper (scientific journal)

  14. Heme ameliorates dextran sodium sulfate-induced colitis through providing intestinal macrophages with noninflammatory profiles

    Hisako Kayama, Masako Kohyama, Daisuke Okuzaki, Daisuke Motooka, Soumik Barman, Ryu Okumura, Masato Muneta, Katsuaki Hoshino, Izumi Sasaki, Wataru Ise, Hiroshi Matsuno, Junichi Nishimura, Tomohiro Kurosaki, Shota Nakamura, Hisashi Arase, Tsuneyasu Kaisho, Kiyoshi Takeda

    Proceedings of the National Academy of Sciences of the United States of America　Vol. 115　No. 33　p. 8418-8423　2018/08/14　Research paper (scientific journal)

  15. Corrigendum: Immune evasion of Plasmodium falciparum by RIFIN via inhibitory receptors

    Fumiji Saito, Kouyuki Hirayasu, Takeshi Satoh, Christian W. Wang, John Lusingu, Takao Arimori, Kyoko Shida, Nirianne Marie Q. Palacpac, Sawako Itagaki, Shiroh Iwanaga, Eizo Takashima, Takafumi Tsuboi, Masako Kohyama, Tadahiro Suenaga, Marco Colonna, Junichi Takagi, Thomas Lavstsen, Toshihiro Horii, Hisashi Arase

    Nature　Vol. 554　No. 7693　p. 554-554　2018/02/22　Research paper (scientific journal)

  16. Myeloperoxidase/HLA Class II Complexes Recognized by Autoantibodies in Microscopic Polyangiitis

    Ryosuke Hiwa, Koichiro Ohmura, Noriko Arase, Hui Jin, Kouyuki Hirayasu, Masako Kohyama, Tadahiro Suenaga, Fumiji Saito, Chikashi Terao, Tatsuya Atsumi, Hirotsugu Iwatani, Tsuneyo Mimori, Hisashi Arase

    Arthritis and Rheumatology　Vol. 69　No. 10　p. 2069-2080　2017/10　Research paper (scientific journal)

  17. Immune evasion of Plasmodium falciparum by RIFIN via inhibitory receptors

    Fumiji Saito, Kouyuki Hirayasu, Takeshi Satoh, Christian W. Wang, John Lusingu, Takao Arimori, Kyoko Shida, Nirianne Marie Q. Palacpac, Sawako Itagaki, Shiroh Iwanaga, Eizo Takashima, Takafumi Tsuboi, Masako Kohyama, Tadahiro Suenaga, Marco Colonna, Junichi Takagi, Thomas Lavstsen, Toshihiro Horii, Hisashi Arase

    Nature　Vol. 552　No. 7683　p. 101-105　2017　Research paper (scientific journal)

  18. Monocyte infiltration into obese and fibrilized tissues is regulated by PILRα

    Masako Kohyama, Sumiko Matsuoka, Kyoko Shida, Fuminori Sugihara, Taiki Aoshi, Kazuki Kishida, Ken J. Ishii, Hisashi Arase

    European Journal of Immunology　Vol. 46　No. 5　p. 1214-1223　2016/05/01　Research paper (scientific journal)

  19. RAG-mediated DNA double-strand breaks activate a cell type-specific checkpoint to inhibit pre-B cell receptor signals

    Jeffrey J. Bednarski, Ruchi Pandey, Emily Schulte, Lynn S. White, Bo Ruei Chen, Gabriel J. Sandoval, Masako Kohyama, Malay Haldar, Andrew Nickless, Amanda Trott, Genhong Cheng, Kenneth M. Murphy, Craig H. Bassing, Jacqueline E. Payton, Barry P. Sleckman

    Journal of Experimental Medicine　Vol. 213　No. 2　p. 209-223　2016/02/08　Research paper (scientific journal)

  20. Sialic acids on varicella-zoster virus glycoprotein B are required for cell-cell fusion

    Tadahiro Suenaga, Maki Matsumoto, Fuminori Arisawa, Masako Kohyama, Kouyuki Hirayasu, Yasuko Mori, Hisashi Arase

    Journal of Biological Chemistry　Vol. 290　No. 32　p. 19833-19843　2015/08/07　Research paper (scientific journal)

  21. Negative regulation of DSS-induced experimental colitis by PILRa

    Kazuki Kishida, Masako Kohyama, Yosuke Kurashima, Yuta Kogure, Jing Wang, Kouyuki Hirayasu, Tadahiro Suenaga, Hiroshi Kiyono, Jun Kunisawa, Hisashi Arase

    International Immunology　Vol. 27　No. 6　p. 307-314　2015/06/01　Research paper (scientific journal)

  22. β2-Glycoprotein I/HLA class II complexes are novel autoantigens in antiphospholipid syndrome

    Kenji Tanimura, Hui Jin, Tadahiro Suenaga, Satoko Morikami, Noriko Arase, Kazuki Kishida, Kouyuki Hirayasu, Masako Kohyama, Yasuhiko Ebina, Shinsuke Yasuda, Tetsuya Horita, Kiyoshi Takasugi, Koichiro Ohmura, Ken Yamamoto, Ichiro Katayama, Takehiko Sasazuki, Lewis L. Lanier, Tatsuya Atsumi, Hideto Yamada, Hisashi Arase

    Blood　Vol. 125　No. 18　p. 2835-2844　2015　Research paper (scientific journal)

  23. Engineering large viral DNA genomes using the CRISPR-Cas9 system

    Tadahiro Suenaga, Masako Kohyama, Kouyuki Hirayasu, Hisashi Arase

    Microbiology and Immunology　Vol. 58　No. 9　p. 513-522　2014/09　Research paper (scientific journal)

  24. Olfactory plays a key role in spatiotemporal pathogenesis of cerebral malaria

    Hong Zhao, Taiki Aoshi, Satoru Kawai, Yuki Mori, Aki Konishi, Muge Ozkan, Yukiko Fujita, Yasunari Haseda, Mikiko Shimizu, Masako Kohyama, Kouji Kobiyama, Kei Eto, Junichi Nabekura, Toshihiro Horii, Tomoko Ishino, Masao Yuda, Hiroaki Hemmi, Tsuneyasu Kaisho, Shizuo Akira, Manabu Kinoshita, Koujiro Tohyama, Yoshichika Yoshioka, Ken J. Ishii, Cevayir Coban

    Cell Host and Microbe　Vol. 15　No. 5　p. 551-563　2014/05/14　Research paper (scientific journal)

    Publisher: 5

  25. Heme-mediated SPI-C induction promotes monocyte differentiation into iron-recycling macrophages

    Malay Haldar, Masako Kohyama, Alex Yick Lun So, Wumesh Kc, Xiaodi Wu, Carlos G. Briseño, Ansuman T. Satpathy, Nicole M. Kretzer, Hisashi Arase, Namakkal S. Rajasekaran, Li Wang, Takeshi Egawa, Kazuhiko Igarashi, David Baltimore, Theresa L. Murphy, Kenneth M. Murphy

    Cell　Vol. 156　No. 6　p. 1223-1234　2014/03/13　Research paper (scientific journal)

  26. Autoantibodies to IgG/HLA class II complexes are associated with rheumatoid arthritis susceptibility

    Hui Jin, Noriko Arase, Kouyuki Hirayasu, Masako Kohyama, Tadahiro Suenaga, Fumiji Saito, Kenji Tanimura, Sumiko Matsuoka, Kosuke Ebina, Kenrin Shi, Noriko Toyama-Sorimachi, Shinsuke Yasuda, Tetsuya Horita, Ryosuke Hiwa, Kiyoshi Takasugi, Koichiro Ohmura, Hideki Yoshikawa, Takashi Saito, Tatsuya Atsumi, Takehiko Sasazuki, Ichiro Katayama, Lewis L. Lanier, Hisashi Arase

    Proceedings of the National Academy of Sciences of the United States of America　Vol. 111　No. 10　p. 3787-3792　2014/03/11　Research paper (scientific journal)

    Publisher: 10

  27. Transport of misfolded endoplasmic reticulum proteins to the cell surface by MHC class II molecules

    Yan Jiang, Noriko Arase, Masako Kohyama, Kouyuki Hirayasu, Tadahiro Suenaga, Hui Jin, Maki Matsumoto, Kyoko Shida, Lewis L. Lanier, Takashi Saito, Hisashi Arase

    International Immunology　Vol. 25　No. 4　p. 235-246　2013/04　Research paper (scientific journal)

  28. The transcription factor BATF controls the global regulators of class-switch recombination in both B cells and T cells

    Wataru Ise, Masako Kohyama, Barbara U. Schraml, Tingting Zhang, Bjoern Schwer, Uttiya Basu, Frederick W. Alt, Jun Tang, Eugene M. Oltz, Theresa L. Murphy, Kenneth M. Murphy

    Nature Immunology　Vol. 12　No. 6　p. 536-543　2011/06　Research paper (scientific journal)

  29. Peripheral CD103+ dendritic cells form a unified subset developmentally related to CD8α+ conventional dendritic cells

    Brian T. Edelson, K. C. Wumesh, Richard Juang, Masako Kohyama, Loralyn A. Benoit, Paul A. Klekotka, Clara Moon, Jörn C. Albring, Wataru Ise, Drew G. Michael, Deepta Bhattacharya, Thaddeus S. Stappenbeck, Michael J. Holtzman, Sun Sang J. Sung, Theresa L. Murphy, Kai Hildner, Kenneth M. Murphy

    Journal of Experimental Medicine　Vol. 207　No. 4　p. 823-836　2010/04　Research paper (scientific journal)

  30. CTLA-4 suppresses the pathogenicity of self antigen-specific T cells by cell-intrinsic and cell-extrinsic mechanisms

    Wataru Ise, Masako Kohyama, Katherine M. Nutsch, Hyang Mi Lee, Anish Suri, Emil R. Unanue, Theresa L. Murphy, Kenneth M. Murphy

    Nature Immunology　Vol. 11　No. 2　p. 129-135　2010/02　Research paper (scientific journal)

  31. Role for Spi-C in the development of red pulp macrophages and splenic iron homeostasis

    Masako Kohyama, Wataru Ise, Brian T. Edelson, Peter R. Wilker, Kai Hildner, Carlo Mejia, William A. Frazier, Theresa L. Murphy, Kenneth M. Murphy

    Nature　Vol. 457　No. 7227　p. 318-321　2009/01/15　Research paper (scientific journal)

  32. Batf3 deficiency reveals a critical role for CD8α+ dendritic cells in cytotoxic T cell immunity

    Kai Hildner, Brian T. Edelson, Whitney E. Purtha, Mark Diamond, Hirokazu Matsushita, Masako Kohyama, Boris Calderon, Barbara U. Schraml, Emil R. Unanue, Michael S. Diamond, Robert D. Schreiber, Theresa L. Murphy, Kenneth M. Murphy

    Science　Vol. 322　No. 5904　p. 1097-1100　2008/11/14　Research paper (scientific journal)

  33. Transcription factor Mef2c is required for B cell proliferation and survival after antigen receptor stimulation

    Peter R. Wilker, Masako Kohyama, Michelle M. Sandau, Jörn C. Albring, Osamu Nakagawa, John J. Schwarz, Kenneth M. Murphy

    Nature Immunology　Vol. 9　No. 6　p. 603-612　2008/06　Research paper (scientific journal)

  34. NF-AT-mediated expression of TGF-β1 in tolerant T cells

    Naoko Nakano, Hiroyuki Hosokawa, Masako Kohyama, Nobumichi Hozumi

    Journal of Immunology　Vol. 178　No. 5　p. 3067-3075　2007/03/01　Research paper (scientific journal)

    Publisher: 5

  35. Ca 2+ signaling down-regulates TGF-β1 gene expression in CD4 + T cells

    Masako Kohyama, Yasuhito Yasogi, Naoko Nakano, Wataru Ise, Shuichi Kaminogawa, Nobumichi Hozumi

    Biochemical and Biophysical Research Communications　Vol. 327　No. 2　p. 494-499　2005/02/11　Research paper (scientific journal)

  36. Inducible costimulator-dependent IL-10 production by regulatory T cells specific for self-antigen

    Masako Kohyama, Daisuke Sugahara, Shigeru Sugiyama, Hideo Yagita, Ko Okumura, Nobumichi Hozumi

    Proceedings of the National Academy of Sciences of the United States of America　Vol. 101　No. 12　p. 4192-4197　2004/03/23　Research paper (scientific journal)

  37. Molecular basis of antigen recognition by insulin specific T cell receptor

    Shigeru Sugiyama, Masako Kohyama, Masayuki Oda, Takachika Azuma, Joan E. Wither, Nobumichi Hozumi

    Immunology Letters　Vol. 91　No. 2-3　p. 133-139　2004/02/15　Research paper (scientific journal)

  38. The IL-4 production capability of different strains of naive CD4+ T cells controls the direction of the T<inf>h</inf> cell response

    Ryoji Yagi, Wataru Suzuki, Noriyasu Seki, Masako Kohyama, Tadahiro Inoue, Takao Arai, Masato Kubo

    International Immunology　Vol. 14　No. 1　p. 1-11　2002　Research paper (scientific journal)

  39. IL-4-mediated development of TGF-β1-producing cells from naïve CD4+ T cells through a STAT6-independent mechanism

    Masako Kohyama, Daisuke Sugahara, Hiroyuki Hosokawa, Masato Kubo, Nobumichi Hozumi

    European Journal of Immunology　Vol. 31　No. 12　p. 3659-3666　2001　Research paper (scientific journal)

  40. Manipulation of cytokine production from CD8(+) T cells by means of amino acid-substituted analogs of a peptide antigen

    M Totsuka, M Kohyama, M Kakehi, S Hachimura, T Hisatsune, S Kaminogawa

    ANIMAL CELL TECHNOLOGY: CHALLENGES FOR THE 21ST CENTURY　p. 149-153　1999　Research paper (international conference proceedings)

  41. Enhancement of antigen-specific IFN-γ production from CD8+ T cells by a single amino acid-substituted peptide derived from bovine α(s1)-casein

    Mamoru Totsuka, Masahiro Kakehi, Masako Kohyama, Satoshi Hachimura, Tatsuhiro Hisatsune, Shuichi Kaminogawa

    Clinical Immunology and Immunopathology　Vol. 88　No. 3　p. 277-286　1998/09　Research paper (scientific journal)

    Publisher: Academic Press Inc.

  42. Selective induction of CD8+ T cell functions by single substituted analogs of an antigenic peptide: Distinct signals for IL-10 production

    Masako Kohyama, Masahiro Kakehi, Mamoru Totsuka, Satoshi Hachimura, Tatsuhiro Hisatsune, Shuichi Kaminogawa

    FEBS Letters　Vol. 423　No. 2　p. 138-142　1998/02/20　Research paper (scientific journal)

  43. Analysis of cytokine producing activity of intestinal intraepithelial T cells from TCR β-chain and δ-chain mutant mice

    Masako Kohyama, Satoshi Hachimura, Masanobu Nanno, Hiromichi Ishikawa, Shuichi Kaminogawa

    Microbiology and Immunology　Vol. 41　No. 4　p. 353-359　1997　Research paper (scientific journal)

  44. Analysis of cytokine production from intestinal intraepithelial lymphocytes using T cell receptor beta-chain and delta-chain mutant mice

    M Kohyama, S Hachimura, M Nanno, H Ishikawa, S Kaminogawa

    ANIMAL CELL TECHNOLOGY: BASIC & APPLIED ASPECTS, VOL 8　p. 391-395　1997　Research paper (international conference proceedings)

  45. Oral administration of antigen does not influence the proliferation and IFN-γ production of responsive CD8+ T cells but enables to establish T cell clones with different lymphokine production profile

    Ken Ichi Nishijima, Tatsuhiro Hisatsune, Hiroko Kato, Masako Kohyama, Masahiro Kakehi, Satoshi Hachimura, Shuichi Kaminogawa

    Cytotechnology　Vol. 25　No. 1-3　p. 89-100　1997　Research paper (international conference proceedings)

  46. Enhancing effect of interleukin-4 on the secretion of interferon-γ by α<inf>s1</inf>-casein-specific CD8+ T Cells

    Ken Ichi Nishijima, Masako Kohyama, Tatsuhiro Hisatsune, Hiroko Kato, Masahiro Kakehi, Shuichi Kaminogawa

    Bioscience, Biotechnology and Biochemistry　Vol. 61　No. 7　p. 1156-1162　1997/01　Research paper (scientific journal)

  47. Difference in signal transduction for IL-10 and IFN-γ production in a CD8+ T cell clone

    Yuji Minai, Masao Goto, Masako Kohyama, Tatsuhiro Hisatsune, Ken Ichi Nishijima, Shuichi Kaminogawa

    Cellular Immunology　Vol. 172　No. 2　p. 200-204　1996/09/15　Research paper (scientific journal)

  48. CD8+ T cells specific to the exogenous antigen: Mode of antigen recognition and possible implication in immunosuppression

    T. Hisatsune, K. I. Nishijima, M. Kohyama, H. Kato, S. Kaminogawa

    Journal of Immunology　Vol. 154　No. 1　p. 88-96　1995　Research paper (scientific journal)

  49. Anti-il-10 antibody enhances the proliferation of cd8+ T cell clones: Autoregulatory role of murine IL-10 in cd8+ T cells

    Ken Ichi Nishijima, Tatsuhiro Hisatsune, Yuji Minai, Masako Kohyama, Shuichi Kaminogawa

    Cellular Immunology　Vol. 154　No. 1　p. 193-201　1994/03　Research paper (scientific journal)

  50. Autoreactive CD8+ t cell clones producing immune suppressive lymphokines IL-10 and interferon-γ

    Tatsuhiro Hisatsune, Ken Ichi Nishijima, Yuji Minai, Masako Kohyama, Shuichi Kaminogawa

    Cellular Immunology　Vol. 154　No. 1　p. 181-192　1994/03　Research paper (scientific journal)

  51. SUPPRESSIVE LYMPHOKINES PRODUCED BY CD8+ T-CELLS

    NISHIJIMA K, HISATSUNE T, MINAI Y, HIRAHARA K, KOHYAMA M, KAMINOGAWA S

    ANIMAL CELL TECHNOLOGY: BASIC & APPLIED ASPECTS, VOL 6　p. 561-565　1994

Misc. 22

  1. ウイルス感染による免疫応答とサイトカインストーム

    香山 雅子, 荒瀬 尚

    実験医学 「サイトカインストーム／ウィズコロナ時代の研究」　Vol. 39　No. 4　p. 524-529　2021/03　Article, review, commentary, editorial, etc. (scientific journal)

    Publisher: (株)羊土社

  2. 新たなネフリンタンパク質とHLAクラスIIの複合体 ステロイド感受性ネフローゼ症候群発症の新たなメカニズム(Novel nephrin protein/HLA classII complexes: A new mechanism of steroid sensitive nephrotic syndrome)

    堀之内 智子, 長野 智那, 山村 智彦, 香山 雅子, 野津 寛大, 飯島 一誠, 荒瀬 尚

    日本小児腎臓病学会雑誌　Vol. 33　No. 1Suppl.　p. 88-88　2020/12

    Publisher: (一社)日本小児腎臓病学会

  3. DNA/HLAクラスII複合体によるDNA応答性B細胞の活性化

    辻 英輝, 大村 浩一郎, 荒瀬 規子, 香山 雅子, 末永 忠広, 三森 経世, 荒瀬 尚

    日本臨床免疫学会総会プログラム・抄録集　Vol. 46回　p. 86-86　2018/11

    Publisher: 日本臨床免疫学会

  4. DNA/HLAクラスII複合体によるDNA応答性B細胞の活性化

    辻 英輝, 大村 浩一郎, 荒瀬 規子, 香山 雅子, 末永 忠広, 三森 経世, 荒瀬 尚

    日本臨床免疫学会総会プログラム・抄録集　Vol. 46回　p. 123-123　2018/11

    Publisher: 日本臨床免疫学会

  5. 脾臓や肝臓の組織マクロファージとその分化制御機構

    香山雅子

    炎症と免疫　Vol. 26　No. 3　p. 192-196　2018/05　Article, review, commentary, editorial, etc. (scientific journal)

    Publisher: (株)先端医学社

  6. 組織マクロファージのサブセット

    香山雅子

    周産期医学　Vol. 47　No. 12　p. 1547-1553　2017/12　Article, review, commentary, editorial, etc. (scientific journal)

    Publisher: (株)東京医学社

  7. Antiphospholipid syndrome and anti-prothrombin/HLA-DR antibody

    Satoko Morikami, Kenji Tanimura, Masashi Deguchi, Yasuhiko Ebina, Noriko Arase, Koyuki Hirayasu, Tadahiro Suenaga, Masako Kohyama, Tatsuya Atsumi, Hideto Yamada, Hisashi Arase

    JOURNAL OF REPRODUCTIVE IMMUNOLOGY　Vol. 118　p. 117-117　2016/11　Research paper, summary (international conference)

  8. 抗リン脂質抗体症候群における抗Prothrombin/HLA-DR抗体

    森上 聡子, 谷村 憲司, 出口 雅士, 蝦名 康彦, 荒瀬 規子, 平安 恒幸, 末永 忠広, 香山 雅子, 渥美 達也, 山田 秀人, 荒瀬 尚

    Reproductive Immunology and Biology　Vol. 31　No. 1-2　p. 110-110　2016/11

    Publisher: 日本生殖免疫学会

  9. Dietary iron and transcription factor Spi-C regulate gut homeostasis through maintenance of CX(3)CR1(high) CD11b(+) CD11c(+) cells

    H. Kayama, M. Kohyama, H. Arase, K. Takeda

    EUROPEAN JOURNAL OF IMMUNOLOGY　Vol. 46　p. 470-470　2016/08　Research paper, summary (international conference)

  10. Erdheim Chester病における遺伝子学的解析

    村上 有香子, 荒瀬 規子, 平安 恒幸, 香山 雅子, 信田 京子, 金田 眞理, 楊 飛, 楊 伶俐, 荒瀬 尚, 片山 一朗

    日本皮膚科学会雑誌　Vol. 126　No. 5　p. 950-950　2016/05

    Publisher: (公社)日本皮膚科学会

  11. 食餌鉄依存的な腸管CX3CR1high制御性ミエロイド細胞維持機構

    香山 尚子, 香山 雅子, 竹田 潔

    日本臨床免疫学会会誌　Vol. 38　No. 4　p. 270-270　2015/09

    Publisher: (一社)日本臨床免疫学会

  12. MPO/HLA class II複合体は顕微鏡的多発血管炎における自己抗体の標的である

    日和 良介, 大村 浩一郎, 荒瀬 規子, 金 暉, 平安 恒幸, 香山 雅子, 末永 忠広, 齋藤 史路, 岩谷 博次, 渥美 達也, 寺尾 知可史, 三森 経世, 荒瀬 尚

    日本臨床免疫学会会誌　Vol. 38　No. 4　p. 326-326　2015/09

    Publisher: 日本臨床免疫学会

  13. 組織マクロファージのサブセットとその分化機構

    香山 雅子

    化学と生物　Vol. 53　No. 9　p. 593-599　2015/08

    Publisher: (公社)日本農芸化学会

  14. AUTOANTIBODIES IN RHEUMATOID ARTHRITIS SPECIFICALLY RECOGNIZE IGG HEAVY CHAIN COMPLEXED WITH HLA-DR, WHICH IS STRONGLY ASSOCIATED WITH RHEUMATOID ARTHRITIS SUSCEPTIBILITY

    H. Jin, N. Arase, K. Hirayasu, M. Kohyama, T. Suenaga, F. Saito, K. Tanimura, S. Matsuoka, K. Ebina, K. Shi, S. Yasuda, T. Horita, R. Hiwa, K. Takasugi, K. Ohmura, H. Yoshikawa, T. Saito, T. Atsumi, T. Sasazuki, I. Katayama, L. L. Lanier, H. Arase

    ANNALS OF THE RHEUMATIC DISEASES　Vol. 73　p. 512-512　2014/06　Research paper, summary (international conference)

  15. 脾臓マクロファージサブセットの機能

    香山 雅子

    細胞工学　Vol. 31　No. 11　p. 1210-1213　2012/11　Article, review, commentary, editorial, etc. (scientific journal)

    Publisher: (株)学研メディカル秀潤社

  16. 【さまざまのレギュラトリーT細胞】IL-10産生自己反応性CD4+ICOS+T細胞の免疫抑制活性と誘導条件

    香山 雅子, 穂積 信道

    臨床免疫　Vol. 42　No. 5　p. 499-503　2004/11

    Publisher: (有)科学評論社

  17. 免疫調節・免疫寛容 Tr細胞によるbystander suppression

    香山 雅子, 穂積 信道

    Annual Review免疫　Vol. 2001　p. 237-243　2000/11

    Publisher: (株)中外医学社

  18. Erratum: Analysis of cytokine producing activity of intestinal, intraepithelial T cells from TCR β-chain and δ-chain mutant mice (Microbiology and Immunology (1997) 41:4 (353-359)

    Masako Kohyama, Satoshi Hachimura, Masanobu Nanno, Hiromichi Ishikawa, Shuichi Kaminogawa

    Microbiology and Immunology　Vol. 44　No. 4　p. 333-333　2000

  19. Cytolytic and IFN-γ-producing activities of γδ T cells in the mouse intestinal epithelium are T cell receptor-β-chain dependent

    Masako Kohyama, Masanobu Nanno, Mariko Kawaguchi-Miyashita, Shinichiro Shimada, Mamoru Watanabe, Toshifumi Hibi, Schuichi Kaminogawa, Hiromichi Ishikawa

    Proceedings of the National Academy of Sciences of the United States of America　Vol. 96　No. 13　p. 7451-7455　1999/06/22

  20. ヒト細胞傷害性Tリンパ球(CTL)誘導のためのCD4+T細胞のリサイクル

    西條 篤, 林田 みどり, 香山 雅子, 八杉 朋子[小林], 青木 基子, 加藤 麻矢子, 飯村 恵美, 鶴嶋 英夫, 坪井 康次, 能勢 忠男

    組織培養研究　Vol. 18　No. 1　p. 48-48　1999/03

    Publisher: 日本組織培養学会

  21. 免疫トレランスをめぐって 経口トレランスと調節性T細胞

    香山 雅子, 上野川 修一

    臨床免疫　Vol. 28　No. 10　p. 1257-1260　1996/10

    Publisher: (有)科学評論社

  22. 免疫学進展の歴史と現状

    香山 雅子, 上野川 修一, 石川 博通

    Medicina　Vol. 32　No. 3　p. 422-428　1995/03

    Publisher: (株)医学書院

Publications 1

  1. ウイルス感染による免疫応答とサイトカインストーム

    荒瀬 尚, 香山 雅子

    羊土社　2021/03

Presentations 1

  1. MHC-IIを標的としたウイルスの免疫逃避機構による自己免疫疾患の発症機序

    香山 雅子

    第166回日本獣医学会学術集会　2023/09/06

Other 6

  1. 「自己免疫疾患」 自己免疫疾患の要因、発症メカニズム（腸内細菌と疾患など）、治療法

    2025/06 -

  2. 「アレルギーと免疫」アレルギー反応の機序、関与する免疫細胞、制御方法

    2025/05 -

  3. 粘膜免疫のしくみ

    2025/03 -

  4. 自然免疫系の細胞の新たなる機能

    2025/02 -

  5. 自己と非自己の識別、多様性の獲得

    2024/11 -

  6. 免疫とは：感染症と闘う生体防御システム

    2024/10 -

Institutional Repository 1

Content Published in the University of Osaka Institutional Repository (OUKA)

  1. Positive and negative regulation of the Fcγ receptor–stimulating activity of RNA-containing immune complexes by RNase

    Naito Ryota, Ohmura Koichiro, Higuchi Shuhei, Nakai Wataru, Kohyama Masako, Mimori Tsuneyo, Morinobu Akio, Arase Hisashi

    JCI Insight　Vol. 8　No. 16　2023/08/22