Lack of Association Between Dietary Fiber Intake and Kidney Failure Among Patients With Chronic Kidney Disease: The Chronic Kidney Disease-Japan Cohort Study.

Koki Hattori, Yusuke Sakaguchi, Yoshitaka Isaka, Takahiro Imaizumi, Shoichi Maruyama, Masafumi Fukagawa

Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation　2025/06/28　Research paper (scientific journal)

Acute Antibody-Mediated Rejection Associated with Anti-MICA Antibodies in Long-Term Kidney Transplant: A Case Study.

Hiroaki Yonishi, Tomoko Namba-Hamano, Shigeaki Nakazawa, Kazuaki Yamanaka, Yoichi Kakuta, Hiroki Hashiguchi, Yuki Kawano, Takuya Kubota, Maho Tokuchi, Hiroki Okushima, Shinsuke Sakai, Atsushi Takahashi, Toyofumi Abe, Ryoichi Imamura, Norio Nonomura, Yoshitaka Isaka

Nephron　p. 1-6　2025/06/24　Research paper (scientific journal)

Rac1 Suppression by the Focal Adhesion Protein GIT ArfGAP2 and Podocyte Protection.

Naoyuki Shimada, Jun Matsuda, Kana Asano-Matsuda, Maho Tokuchi, Lamine Aoudjit, Agnieszka Masztalerz, Serge Lemay, Tomoko Takano, Yoshitaka Isaka

Journal of the American Society of Nephrology : JASN　Vol. 36　No. 6　p. 1088-1104　2025/06/01　Research paper (scientific journal)

Delayed inactivation of TRPC6 as a determinative characteristic of FSGS-associated variants.

Ryo Okada, Reiko Sakaguchi, Tatsuya Komaki, Ryu Nonaka, Onur K Polat, Takanori Kihara, Katsuhiko Asanuma, Takeshi Yamamoto, Yoshitaka Isaka, Yasuo Mori, Masayuki X Mori

The Journal of biological chemistry　Vol. 301　No. 6　p. 110256-110256　2025/06　Research paper (scientific journal)

Kidney Function Trajectories with Tolvaptan in ADPKD Patients with CKD-G5.

Akinari Sekine, Junichi Hoshino, Toshio Mochizuki, Shinya Nakatani, Saori Nishio, Tatsuya Suwabe, Hiroki Hayashi, Hirayasu Kai, Koichi Seta, Fumihiko Hattanda, Sumi Hidaka, Kazushige Hanaoka, Mahiro Kurashige, Hiroshi Kataoka, Kiyotaka Uchiyama, Keiji Shimazu, Eiji Ishikawa, Yosuke Shimada, Haruna Kawano, Ken Tsuchiya, Shigeo Horie, Ichiei Narita, Yoshitaka Isaka, Satoru Muto

Kidney international reports　Vol. 10　No. 6　p. 1864-1873　2025/06　Research paper (scientific journal)

d-Alanine, a Circadian Metabolite that Regulates Glucose Metabolism and Viral Infection.

Tomonori Kimura, Shinsuke Sakai, Yoshitaka Isaka

Chembiochem : a European journal of chemical biology　Vol. 26　No. 7　2025/04/01　Research paper (scientific journal)

Status of initial treatment for rapidly progressive glomerulonephritis in Japan: analysis of a personal clinical records database.

Joichi Usui, Tomonori Kimura, Kunihiro Yamagata, Kentaro Nakajima, Shuzo Kaneko, Ken-Ei Sada, Naotake Tsuboi, Hirokazu Okada, Keiju Hiromura, Yoshitaka Isaka, Ichiei Narita

Clinical and experimental nephrology　2025/03/27　Research paper (scientific journal)

5-aminolaevulinic acid with sodium ferrous citrate alleviated kidney injury and fibrosis in a unilateral ureteral obstruction model.

Kuai Ma, Masayuki Fujino, Yang Yang, Zhaolun Ding, Xin Hu, Hidenori Ito, Kiwamu Takahashi, Motowo Nakajima, Yoshitaka Isaka, Xiao-Kang Li

International immunopharmacology　Vol. 150　p. 114321-114321　2025/03/26　Research paper (scientific journal)

Oxidized low-density lipoprotein potentiates angiotensin II-induced Gq activation through the AT1-LOX1 receptor complex.

Jittoku Ihara, Yibin Huang, Yoichi Takami, Yoichi Nozato, Toshimasa Takahashi, Akemi Kakino, Cheng Wang, Ziwei Wang, Yu Guo, Weidong Liu, Nanxiang Yin, Ryoichi Ohara, Taku Fujimoto, Shino Yoshida, Kazuhiro Hongyo, Hiroshi Koriyama, Hiroshi Akasaka, Hikari Takeshita, Shinsuke Sakai, Kazunori Inoue, Yoshitaka Isaka, Hiromi Rakugi, Tatsuya Sawamura, Koichi Yamamoto

eLife　Vol. 13　2025/03/25　Research paper (scientific journal)

Temporal changes of the life and renal prognoses of patients with rapidly progressive glomerulonephritis in Japan, 1989-2019.

Kentaro Nakajima, Shuzo Kaneko, Joichi Usui, Naotake Tsuboi, Hitoshi Sugiyama, Shoichi Maruyama, Yoshitaka Isaka, Ichiei Narita, Kunihiro Yamagata

Clinical and experimental nephrology　2025/03/25　Research paper (scientific journal)

Therapeutic effect of TTR siRNA on hereditary transthyretin amyloidosis (ATTRv) nephropathy.

Takahiro Ajiki, Tatsuhiko Ozono, Fusako Sera, Hiroaki Yonishi, Jun Matsuda, César Aguirre, Keita Kakuda, Yumiko Yasuhara, Yoshitaka Isaka, Yasushi Sakata, Kensuke Ikenaka, Hideki Mochizuki

Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis　p. 1-8　2025/02/23　Research paper (scientific journal)

Plant-Dominant Low-Protein Diets: A Promising Dietary Strategy for Mitigating Disease Progression in People with Chronic Kidney Disease-A Comprehensive Review.

Jun-Ya Kaimori, Yusuke Sakaguchi, Tatsufumi Oka, Yoshitaka Isaka

Nutrients　Vol. 17　No. 4　2025/02/11　Research paper (scientific journal)

Clinically meaningful eGFR slope as a surrogate endpoint differs across CKD stages and slope evaluation periods: the CKD-JAC study.

Takahiro Imaizumi, Hirotaka Komaba, Takayuki Hamano, Masaomi Nangaku, Kenta Murotani, Takeshi Hasegawa, Naohiko Fujii, Kosaku Nitta, Yoshitaka Isaka, Takashi Wada, Shoichi Maruyama, Masafumi Fukagawa

Clinical kidney journal　Vol. 18　No. 2　2025/02　Research paper (scientific journal)

Impact of Immunosuppressive Drug Concentrations on Microvascular Inflammation, Negative Donor-Specific Antibodies, and C4d-Negative Status in Kidney Transplant Recipients.

Yoichi Kakuta, Yoko Maegawa-Higa, Soichi Matsumura, Shota Fukae, Ryo Tanaka, Hiroaki Yonishi, Shigeaki Nakazawa, Tomoko Namba-Hamano, Yoshitaka Isaka, Norio Nonomura

Clinical transplantation　Vol. 39　No. 2　2025/02　Research paper (scientific journal)

Detection of Fast Decliner of Diabetic Kidney Disease Using Chiral Amino Acid Profiling: A Pilot Study.

Yosuke Hirakawa, Tomonori Kimura, Shinsuke Sakai, Masayuki Mizui, Masashi Mita, Yoshitaka Isaka, Masaomi Nangaku, Reiko Inagi

Chemistry & biodiversity　2025/01/30　Research paper (scientific journal)

A Novel Heterozygous and Pathogenic Variant of the HNF1B Gene Associated with Autosomal Dominant Tubulointerstitial Kidney Disease with a Broad Spectrum of Extrarenal Phenotypes: A Case Report.

Jun-Ya Kaimori, Jun Matsuda, Asif Jan, Yuki Kawano, Takayuki Kawaoka, Yuta Asahina, Yohei Doi, Tatsufumi Oka, Miho Nagata, Yasuki Ishihara, Yohei Miyashita, Toshihiro Asano, Yusuke Sakaguchi, Yoshitaka Isaka

Internal medicine (Tokyo, Japan)　2025/01/15　Research paper (scientific journal)

Long-Term Efficacy and Safety of Upacicalcet in Japanese Hemodialysis Patients with Secondary Hyperparathyroidism: Open-Label 52-Week Study.

Takayuki Hamano, Fumihiko Koiwa, Yoshitaka Isaka, Keitaro Yokoyama, Masafumi Fukagawa, Yosuke Inagaki, Yukihisa S Watanabe, Daisuke Honda, Tadao Akizawa

American journal of nephrology　Vol. 56　No. 1　p. 70-84　2025　Research paper (scientific journal)

CKD診療ガイド2024

丸山 彰一, 神田 英一郎, 久米 真司, 猪阪 善隆, 石倉 健司, 臼井 丈一, 内田 啓子, 岡田 浩一, 今田 恒夫, 斎藤 知栄, 鈴木 仁, 田中 哲洋, 坪井 直毅, 中川 直樹, 西尾 妙織, 深水 圭, 本田 浩一, 升谷 耕介, 横山 啓太郎, 和田 淳, 和田 隆志, 和田 健彦, 淺沼 克彦, 旭 浩一, 阿部 雅紀, 石本 卓嗣, 川浪 大治, 駒場 大峰, 佐田 憲映, 祖父江 理, 仲谷 慎也, 中司 敦子, 日比野 聡, 藤井 秀毅, 星野 純一, 細島 康宏, 前嶋 明人, 丸山 之雄, 森山 能仁, 安田 日出夫, 安田 宜成, 山本 卓, 小杉 智規, 日本腎臓学会, CKD診療ガイドライン改訂委員会

日本腎臓学会誌　Vol. 67　No. 1　p. 3-177　2025/01　Research paper (scientific journal)

Age-related TFEB downregulation in proximal tubules causes systemic metabolic disorders and occasional apolipoprotein A4-related amyloidosis.

Jun Nakamura, Takeshi Yamamoto, Yoshitsugu Takabatake, Tomoko Namba-Hamano, Atsushi Takahashi, Jun Matsuda, Satoshi Minami, Shinsuke Sakai, Hiroaki Yonishi, Shihomi Maeda, Sho Matsui, Hideaki Kawai, Isao Matsui, Tadashi Yamamuro, Ryuya Edahiro, Seiji Takashima, Akira Takasawa, Yukinori Okada, Tamotsu Yoshimori, Andrea Ballabio, Yoshitaka Isaka

JCI insight　2024/12/19　Research paper (scientific journal)

腎移植患者におけるSGLT2阻害薬の腎保護効果

難波 倫子, 高橋 篤史, 土井 洋平, 平岡 敦子, 余西 洋明, 酒井 晋介, 水井 理之, 濱野 高行, 猪阪 善隆

日本臨床腎移植学会雑誌　Vol. 12　No. 2　p. 277-283　2024/12　Research paper (scientific journal)

A nationwide questionnaire study evaluated kidney injury associated with Beni-koji tablets in Japan.

Maki SHINZAWA, Isao MATSUI, Yohei DOI, Ayumi MATSUMOTO, Atsushi TAKAHASHI, Masaomi NANGAKU, Yoshitaka ISAKA, Masami Ono, Yuriko Yonekura, Yuki Nishizawa, Masahiro Azuma, Ryousuke Aoki, Koji Inagaki, Daiki Nagawa, Ken-ichi Miyoshi, Yasutaka Kamikawa, Yuri Kasagi, Seiji Kishi, Sinsuke Motegi, Hitoshi Suzuki, Shioko Okada, Kazufumi Nomura, Tomoaki Itoh, Yosuke Saka, Takayuki Hamano, Makoto Ogi, Imasawa Toshiyuki, Ken Shibuya, Kazuhiro Yoshikawa, Shu Ushimaru, Hideki Fujii, Koji Sato, Kaori Hayashi, Masato Habuka, Akihiro Tojo, Hideyuki Katori, Akiko Torii, Reina Miyazaki, TAkehiko Tokura, Yoshikazu Nemoto, Masahito Baba, Risshi Kudo, atsushi saito, Ryuta Fujimura, Takashi Araki, Hiraku Yoshida, Takanori Miyazaki, Yosuke Osaki, Saori Nishio, Yasunori Utsunomiya, Toshiki Doi, Mitsuhiro Sato, Yoei Miyabe, Tadashi Sofue, Masaaki Izumi, Togo Aoyama, Keisuke Osaki, Ryuuji Iwatani, Noriyuki Iehara, Matsui Mikoto, Tatsuo Tsukamoto, Yoshiharu Nishitani, Yoshio Konishi, Shihomi Maeda, Yuki Kawano, Keisuke Maruyama, Aya Nakamori, Eiji Ishikawa, Norihisa Osawa, Masami Komeda, Ritsuko Hasegawa, Satoka Shiratori-Aso, Hiroyuki Deguchi, Toshiyuki Aoki, Shuzo Kobayashi, Daisuke Ichikawa, Tomoko Yokoyama, Tetsuya Nagae, Takayuki Sakai, Shigeru Shibata, Jun Ino, Motokazu Matsuura, Tomonari Okada, Takayuki Toda, Ikuo Nukui, Jin Oshikawa

Kidney International　2024/12　Research paper (scientific journal)

Prevalence of patent processus vaginalis diagnosed using laparoscopy during peritoneal dialysis catheter insertion and subsequent genital edema: A prospective observational study.

Terumasa Hayashi, Susumu Miyazaki, Kazuhiro Iwase, Taisuke Takatsuka, Daisuke Yoshimura, Tomohiro Kawamura, Yukimasa Iwata, Hiroki Okushima, Yoshiyasu Ueda, Yoshitaka Isaka

Blood purification　p. 1-14　2024/11/29　Research paper (scientific journal)

Seasonal variations in the association between proteinuria, CKD, and kidney failure

Takayuki Kawaoka, Yusuke Sakaguchi, Tatsufumi Oka, Yuta Asahina, Koki Hattori, Yohei Doi, Nobuhiro Hashimoto, Yasuo Kusunoki, Satoko Yamamoto, Masafumi Yamato, Ryohei Yamamoto, Isao Matsui, Masayuki Mizui, Jun-Ya Kaimori, Yoshitaka Isaka

Nephrology Dialysis Transplantation　2024/11/21　Research paper (scientific journal)

Determination of urine volume and glomerular filtration rate using d-serine and d-asparagine.

Ryo Tanaka, Shinsuke Sakai, Ayumu Taniguchi, Masataka Kawamura, Yoko Higa-Maegawa, Soichi Matsumura, Shota Fukae, Shigeaki Nakazawa, Shihoko Kimura-Ohba, Masaru Horio, Shiro Takahara, Ryoichi Imamura, Norio Nonomura, Masayuki Mizui, Yoshitaka Isaka, Yoichi Kakuta, Tomonori Kimura

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association　Vol. 40　No. 7　p. 1374-1383　2024/11/21　Research paper (scientific journal)

移植内科医(Transplant Physician)が術前、周術期管理から参画した当院の膵腎同時移植の新体制

余西 洋明, 川野 祐暉, 徳地 真帆, 難波 倫子, 高橋 篤史, 猪阪 善隆, 富丸 慶人, 小林 省吾, 佐々木 一樹, 岩上 佳史, 山田 大作, 野田 剛広, 土岐 祐一郎, 江口 英利, 角田 洋一, 中澤 成晃, 山中 和明, 野々村 祝夫, 宮下 和幸, 小澤 栄稔, 下村 伊一郎, 森本 貴子, 加門 千寿

移植　Vol. 59　No. 2　p. 210-210　2024/11　Research paper (scientific journal)

移植内科医(Transplant Physician)が術前、周術期管理から参画した当院の膵腎同時移植の新体制

余西 洋明, 川野 祐暉, 徳地 真帆, 難波 倫子, 高橋 篤史, 猪阪 善隆, 富丸 慶人, 小林 省吾, 佐々木 一樹, 岩上 佳史, 山田 大作, 野田 剛広, 土岐 祐一郎, 江口 英利, 角田 洋一, 中澤 成晃, 山中 和明, 野々村 祝夫, 宮下 和幸, 小澤 栄稔, 下村 伊一郎, 森本 貴子, 加門 千寿

移植　Vol. 59　No. 2　p. 210-210　2024/11　Research paper (scientific journal)

Enhanced fatty acid oxidation by selective activation of PPARα alleviates autoimmunity through metabolic transformation in T-cells.

Satoshi Masuyama, Masayuki Mizui, Masashi Morita, Takatomo Shigeki, Hisakazu Kato, Takeshi Yamamoto, Yusuke Sakaguchi, Kazunori Inoue, Tomoko Namba-Hamano, Isao Matsui, Tatsusada Okuno, Ryohei Yamamoto, Seiji Takashima, Yoshitaka Isaka

Clinical immunology (Orlando, Fla.)　Vol. 268　p. 110357-110357　2024/11　Research paper (scientific journal)

Kinetic analysis of D-Alanine upon oral intake in humans.

Tomonori Kimura, Shinsuke Sakai, Masaru Horio, Shiro Takahara, Shoto Ishigo, Maiko Nakane, Eiichi Negishi, Hiroshi Imoto, Masashi Mita, Kenji Hamase, Yoko Higa-Maekawa, Yoichi Kakuta, Masayuki Mizui, Yoshitaka Isaka

Amino acids　Vol. 56　No. 1　p. 61-61　2024/10/14　Research paper (scientific journal)

Empagliflozin protects the kidney by reducing toxic ALB (albumin) exposure and preventing autophagic stagnation in proximal tubules.

Sho Matsui, Takeshi Yamamoto, Yoshitsugu Takabatake, Atsushi Takahashi, Tomoko Namba-Hamano, Jun Matsuda, Satoshi Minami, Shinsuke Sakai, Hiroaki Yonishi, Jun Nakamura, Shihomi Maeda, Ayumi Matsumoto, Isao Matsui, Motoko Yanagita, Yoshitaka Isaka

Autophagy　Vol. 21　No. 3　p. 583-597　2024/10/10　Research paper (scientific journal)

Self-Supervised Learning for Feature Extraction from Glomerular Images and Disease Classification with Minimal Annotations

Masatoshi Abe, Hirohiko Niioka, Ayumi Matsumoto, Yusuke Katsuma, Atsuhiro Imai, Hiroki Okushima, Shingo Ozaki, Naohiko Fujii, Kazumasa Oka, Yusuke Sakaguchi, Kazunori Inoue, Yoshitaka Isaka, Isao Matsui

Journal of the American Society of Nephrology　2024/10/09　Research paper (scientific journal)

Protocol for the nationwide registry of patients with polycystic kidney disease: japanese national registry of PKD (JRP).

Shinya Nakatani, Haruna Kawano, Mai Sato, Junichi Hoshino, Saori Nishio, Kenichiro Miura, Akinari Sekine, Tatsuya Suwabe, Sumi Hidaka, Hiroshi Kataoka, Eiji Ishikawa, Keiji Shimazu, Kiyotaka Uchiyama, Takuya Fujimaru, Tomofumi Moriyama, Mahiro Kurashige, Wataru Shimabukuro, Fumihiko Hattanda, Tomoki Kimura, Yusuke Ushio, Shun Manabe, Hirofumi Watanabe, Michihiro Mitobe, Koichi Seta, Yosuke Shimada, Hirayasu Kai, Kan Katayama, Daisuke Ichikawa, Hiroki Hayashi, Kazushige Hanaoka, Toshio Mochizuki, Koichi Nakanishi, Ken Tsuchiya, Shigeo Horie, Yoshitaka Isaka, Satoru Muto

Clinical and experimental nephrology　Vol. 28　No. 10　p. 1004-1015　2024/10　Research paper (scientific journal)

Performance of the New CKD-EPI Creatinine-and Cystatin C-based Glomerular Filtration Rate Estimation Equation in Living Kidney Donor Candidate.

Yoichi Kakuta, Yoko Maegawa-Higa, Soichi Matsumura, Shota Fukae, Ryo Tanaka, Hiroaki Yonishi, Shigeaki Nakazawa, Kazuaki Yamanaka, Yoshitaka Isaka, Norio Nonomura

Transplantation direct　Vol. 10　No. 10　2024/10　Research paper (scientific journal)

Risedronate prevents exercise-induced hypercalcemia but not nausea or vomit in humans: a double blind randomized controlled trial.

Masamitsu Senda, Naohiko Fujii, Toshimitsu Ito, Yoshitaka Isaka, Toshiki Moriyama, Takayuki Hamano

Scientific reports　Vol. 14　No. 1　p. 22534-22534　2024/09/28　Research paper (scientific journal)

Potassium nitrate for contrast-induced nephropathy and cardiovascular outcomes: further valid evidence is indispensable.

Yusuke Sakaguchi, Yuta Asahina, Yoshitaka Isaka

European heart journal　Vol. 45　No. 34　p. 3184-3184　2024/09/07　Research paper (scientific journal)

Donor Candidate GFR Calculatorの日本人における有用性の検討

比嘉 洋子, 角田 洋一, 松村 聡一, 深江 彰太, 田中 亮, 余西 洋明, 中澤 成晃, 山中 和明, 蔦原 宏一, 岸川 英史, 高尾 徹也, 猪阪 善隆, 野々村 祝夫

移植　Vol. 59　No. 総会臨時　p. 352-352　2024/09　Research paper (scientific journal)

Guidelines for clinical evaluation of chronic kidney disease in early stages : AMED research on regulatory science of pharmaceuticals and medical devices.

Yuka Sugawara, Eiichiro Kanda, Takayuki Hamano, Seiji Itano, Hirokazu Okada, Koji Tomori, Yusuke Watanabe, Wataru Asakura, Yoshitaka Isaka, Kunitoshi Iseki, Tomoko Usui, Yusuke Suzuki, Mototsugu Tanaka, Rimei Nishimura, Kei Fukami, Kunihiro Matsushita, Jun Wada, Hirotaka Watada, Kohjiro Ueki, Naoki Kashihara, Masaomi Nangaku

Clinical and experimental nephrology　Vol. 28　No. 9　p. 847-865　2024/09　Research paper (scientific journal)

HNF1B新規変異による,膵低形成を伴う常染色体顕性遺伝性間質尿細管腎症の1家系

貝森 淳哉, 松田 潤, 川野 祐暉, 河岡 高征, 朝比奈 悠太, 土井 洋平, 岡 樹史, 坂口 悠介, 永田 美保, 石原 保貴, 宮下 洋平, 朝野 仁裕, 猪阪 善隆

日本腎臓学会誌　Vol. 66　No. 6-W　p. 1097-1097　2024/09

既存抗ドナー特異的抗体陽性症例に対する治療方針と成績 Preformed DSA陽性腎移植への挑戦 最適な治療戦略を目指して

角田 洋一, 比嘉 洋子, 松村 聡一, 深江 彰太, 田中 亮, 余西 洋明, 中澤 成晃, 猪阪 善隆, 野々村 祝夫

移植　Vol. 59　No. 総会臨時　p. 187-187　2024/09

腎移植におけるTransplant Oncology スクリーニングから治療まで

角田 洋一, 比嘉 洋子, 松村 聡一, 深江 彰太, 田中 亮, 余西 洋明, 中澤 成晃, 今村 亮一, 猪阪 善隆, 野々村 祝夫

移植　Vol. 59　No. 総会臨時　p. 269-269　2024/09

エベロリムスの薬物血中濃度の検討 腎移植

深江 彰太, 比嘉 洋子, 松村 聡一, 田中 亮, 余西 洋明, 中澤 成晃, 角田 洋一, 猪阪 善隆, 野々村 祝夫

移植　Vol. 59　No. 総会臨時　p. 293-293　2024/09

Donor Candidate GFR Calculatorの日本人における有用性の検討

比嘉 洋子, 角田 洋一, 松村 聡一, 深江 彰太, 田中 亮, 余西 洋明, 中澤 成晃, 山中 和明, 蔦原 宏一, 岸川 英史, 高尾 徹也, 猪阪 善隆, 野々村 祝夫

移植　Vol. 59　No. 総会臨時　p. 352-352　2024/09

Pathological mechanisms of kidney disease in ageing.

Takeshi Yamamoto, Yoshitaka Isaka

Nature reviews. Nephrology　2024/07/18　Research paper (scientific journal)

Factors affecting the sodium-glucose cotransporter 2 inhibitors-related initial decline in glomerular filtration rate and its possible effect on kidney outcome in chronic kidney disease with type 2 diabetes: The Japan Chronic Kidney Disease Database.

Tomohiko Kanaoka, Hiromichi Wakui, Yuichiro Yano, Hajime Nagasu, Hiroshi Kanegae, Masaomi Nangaku, Yosuke Hirakawa, Naoki Nakagawa, Jun Wada, Kazuhiko Tsuruya, Toshiaki Nakano, Shoichi Maruyama, Takashi Wada, Masaaki Konishi, Takanori Nagahiro, Kunihiro Yamagata, Ichiei Narita, Motoko Yanagita, Yoshio Terada, Shinichi Araki, Masanori Emoto, Hirokazu Okada, Yoshitaka Isaka, Yusuke Suzuki, Takashi Yokoo, Hiromi Kataoka, Eiichiro Kanda, Naoki Kashihara, Kouichi Tamura

Diabetes, obesity & metabolism　Vol. 26　No. 7　p. 2905-2914　2024/07　Research paper (scientific journal)

移植後糖尿病患者に対する糖尿病新規薬剤への期待

難波 倫子, 余西 洋明, 徳地 真帆, 平岡 敦子, 奥嶋 拓樹, 酒井 晋介, 土井 洋平, 高橋 篤史, 濱野 高行, 猪阪 善隆

日本臨床腎移植学会雑誌　Vol. 12　No. 1　p. 44-49　2024/07

臨床各科 難渋症例から学ぶ診療のエッセンス(File193) 急性腎障害をきたした女性

猪阪 善隆, 水井 理之, 松井 功

日本医事新報　No. 5229　p. 12-13　2024/07

Effects of sodium-glucose co-transporter 2 inhibitors on ultrafiltration in patients with peritoneal dialysis: a protocol for a randomized, double-blind, placebo-controlled, crossover trial (EMPOWERED)

Yohei Doi, Maki Shinzawa, Tetsuya Arisato, Hideaki Oka, Ayumi Matsumoto, Harumi Kitamura, Yumi Nakazono, Yoichi Nishiya, Yoshiyasu Ueda, Taro Kamimura, Terumasa Hayashi, Fumiki Yoshihara, Yoshitaka Isaka

Vol. 28　No. 7　p. 629-635　2024/07　Research paper (scientific journal)

Estimated Effect of Restarting Renin-Angiotensin System Inhibitors after Discontinuation on Kidney Outcomes and Mortality

Koki Hattori, Yusuke Sakaguchi, Tatsufumi Oka, Yuta Asahina, Takayuki Kawaoka, Yohei Doi, Nobuhiro Hashimoto, Yasuo Kusunoki, Satoko Yamamoto, Masafumi Yamato, Ryohei Yamamoto, Isao Matsui, Masayuki Mizui, Jun-Ya Kaimori, Yoshitaka Isaka

Journal of the American Society of Nephrology　2024/06/18　Research paper (scientific journal)

Endogenous activation of peroxisome proliferator-activated receptor alpha in proximal tubule cells in counteracting phosphate toxicity.

Yusuke Katsuma, Isao Matsui, Ayumi Matsumoto, Hiroki Okushima, Atsuhiro Imai, Yusuke Sakaguchi, Takeshi Yamamoto, Masayuki Mizui, Shohei Uchinomiya, Hisakazu Kato, Akio Ojida, Seiji Takashima, Kazunori Inoue, Yoshitaka Isaka

American journal of physiology. Renal physiology　2024/06/13　Research paper (scientific journal)

D-アラニンは既日リズムと腎糖新生に影響する

酒井 晋介, 田中 陽一, 木村 志保子, 部坂 篤, 浜瀬 健司, 三田 真史, 土居 雅夫, 木村 友則, 猪阪 善隆

日本腎臓学会誌　Vol. 66　No. 4　p. 610-610　2024/06

加齢による近位尿細管のTFEB活性低下は,全身の脂質代謝を悪化させ,アミロイドーシスの原因となる

中村 隼, 山本 毅士, 難波 倫子, 高橋 篤史, 松田 潤, 南 聡, 酒井 晋介, 前田 志穂美, 松井 翔, 河合 秀亮, 猪阪 善隆

日本腎臓学会誌　Vol. 66　No. 4　p. 572-572　2024/06

D-アラニンは既日リズムと腎糖新生に影響する

酒井 晋介, 田中 陽一, 木村 志保子, 部坂 篤, 浜瀬 健司, 三田 真史, 土居 雅夫, 木村 友則, 猪阪 善隆

日本腎臓学会誌　Vol. 66　No. 4　p. 610-610　2024/06

MondoA and AKI and AKI-to-CKD Transition.

Shihomi Maeda, Shinsuke Sakai, Yoshitsugu Takabatake, Takeshi Yamamoto, Satoshi Minami, Jun Nakamura, Tomoko Namba-Hamano, Atsushi Takahashi, Jun Matsuda, Hiroaki Yonishi, Sho Matsui, Atsuhiro Imai, Ryuya Edahiro, Hitomi Yamamoto-Imoto, Isao Matsui, Seiji Takashima, Ryoichi Imamura, Norio Nonomura, Motoko Yanagita, Yukinori Okada, Andrea Ballabio, Shuhei Nakamura, Tamotsu Yoshimori, Yoshitaka Isaka

Journal of the American Society of Nephrology : JASN　2024/05/31　Research paper (scientific journal)

Evaluating the associations between compliance with CKD guideline component metrics and renal outcomes.

Zannatun Nyma, Kaori Kitaoka, Yuichiro Yano, Hiroshi Kanegae, Nomin Bayaraa, Seiji Kishi, Hajime Nagasu, Toshiaki Nakano, Jun Wada, Shoichi Maruyama, Naoki Nakagawa, Kouichi Tamura, Takashi Yokoo, Motoko Yanagita, Ichiei Narita, Kunihiro Yamagata, Takashi Wada, Kazuhiko Tsuruya, Naoki Nakashima, Yoshitaka Isaka, Masaomi Nangaku, Naoki Kashihara, Hirokazu Okada

Scientific reports　Vol. 14　No. 1　p. 11481-11481　2024/05/20　Research paper (scientific journal)

移植前透析期間が腎移植レシピエントの生存率に与える影響の検討

角田 洋一, 松村 聡一, 深江 彰太, 田中 亮, 余西 洋明, 中澤 成晃, 山中 和明, 難波 倫子, 猪阪 善隆, 野々村 祝夫

日本透析医学会雑誌　Vol. 57　No. Suppl.1　p. 659-659　2024/05

移植前透析期間が腎移植レシピエントの生存率に与える影響の検討

角田 洋一, 松村 聡一, 深江 彰太, 田中 亮, 余西 洋明, 中澤 成晃, 山中 和明, 難波 倫子, 猪阪 善隆, 野々村 祝夫

日本透析医学会雑誌　Vol. 57　No. Suppl.1　p. 659-659　2024/05

Cigarette smoking and progression of kidney dysfunction: a longitudinal cohort study.

Ayako Matsumoto, Yasuyuki Nagasawa, Ryouhei Yamamoto, Maki Shinzawa, Hiromitsu Yamazaki, Kensaku Shojima, Ken Shinmura, Yoshitaka Isaka, Kunitoshi Iseki, Kunihiro Yamagata, Ichiei Narita, Tsuneo Konta, Masahide Kondo, Kazuhiko Tsuruya, Masato Kasahara, Yugo Shibagaki, Shouichi Fujimoto, Koichi Asahi, Tsuyoshi Watanabe, Toshiki Moriyama

Clinical and experimental nephrology　2024/04/06　Research paper (scientific journal)

Development of a three-dimensional HPLC system for the determination of serine, threonine and allo-threonine enantiomers in the plasma of patients with chronic kidney disease

Mai Oyaide, Chiharu Ishii, Takeyuki Akita, Tomonori Kimura, Shinsuke Sakai, Masayuki Mizui, Masashi Mita, Tomomi Ide, Yoshitaka Isaka, Kenji Hamase

Journal of Chromatography A　Vol. 1719　2024/03/29　Research paper (scientific journal)

Evaluation of individual variation of D-amino acids in human plasma by a two-dimensional LC-MS/MS system and application to the early diagnosis of chronic kidney disease

Chiharu Ishii, Takeyuki Akita, Tomonori Kimura, Shinsuke Sakai, Masashi Mita, Tomomi Ide, Yoshitaka Isaka, Kenji Hamase

Analytical Chemistry　Vol. 96　No. 12　p. 4876-4883　2024/03　Research paper (scientific journal)

Association between urinary uric acid excretion and kidney outcome in patients with CKD

Yuta Asahina, Yusuke Sakaguchi, Tatsufumi Oka, Koki Hattori, Takayuki Kawaoka, Yohei Doi, Ryohei Yamamoto, Isao Matsui, Masayuki Mizui, Jun-Ya Kaimori, Yoshitaka Isaka

Scientific Reports　Vol. 14　No. 1　2024/03/01　Research paper (scientific journal)

腎移植後糖尿病の新たな治療戦略 移植後糖尿病患者に対する糖尿病新規薬剤への期待

難波 倫子, 余西 洋明, 奥嶋 拓樹, 酒井 晋介, 高橋 篤史, 猪阪 善隆

日本臨床腎移植学会プログラム・抄録集　Vol. 57回　p. 104-104　2024/02

移植長期経過後に抗MICA抗体による急性抗体関連拒絶を呈した一例

余西 洋明, 難波 倫子, 窪田 卓也, 徳地 真帆, 高橋 篤史, 中澤 成晃, 山中 和明, 阿部 豊文, 角田 洋一, 今村 亮一, 野々村 祝夫, 猪阪 善隆

日本臨床腎移植学会プログラム・抄録集　Vol. 57回　p. 162-162　2024/02

腎移植後重症COVID-19肺炎患者1例の移植腎病理所見の報告

窪田 卓也, 余西 洋明, 難波 倫子, 川野 祐暉, 徳地 真帆, 奥嶋 拓樹, 酒井 晋介, 土井 洋平, 高橋 篤史, 水井 理之, 中澤 成晃, 山中 和明, 角田 洋一, 野々村 祝夫, 猪阪 善隆

日本臨床腎移植学会プログラム・抄録集　Vol. 57回　p. 199-199　2024/02

COVID-19肺炎後に器質化肺炎を発症した腎移植患者の一例

高橋 篤史, 徳地 真帆, 余西 洋明, 難波 倫子, 川野 祐暉, 窪田 卓也, 土井 洋平, 酒井 晋介, 中澤 成晃, 山中 和明, 角田 洋一, 水井 理之, 野々村 祝夫, 猪阪 善隆

日本臨床腎移植学会プログラム・抄録集　Vol. 57回　p. 220-220　2024/02

移植腎膿瘍に対して内科的治療が奏効した一例

徳地 真帆, 余西 洋明, 難波 倫子, 高橋 篤史, 川野 祐暉, 窪田 卓也, 奥嶋 拓樹, 酒井 晋介, 土井 洋平, 中澤 成晃, 山中 和明, 角田 洋一, 野々村 祝夫, 猪阪 善隆

日本臨床腎移植学会プログラム・抄録集　Vol. 57回　p. 221-221　2024/02

Low-dosage active vitamin D modifies the relationship between hypocalcemia and overhydration in patients with advanced chronic kidney disease.

Satoshi Yamaguchi, Takayuki Hamano, Sayoko Yonemoto, Naohiko Fujii, Yoshitaka Isaka

Journal of nephrology　2024/01/05

HKDC1, a target of TFEB, is essential to maintain both mitochondrial and lysosomal homeostasis, preventing cellular senescence

Mengying Cui, Koji Yamano, Kenichi Yamamoto, Hitomi Yamamoto-Imoto, Satoshi Minami, Takeshi Yamamoto, Sho Matsui, Tatsuya Kaminishi, Takayuki Shima, Monami Ogura, Megumi Tsuchiya, Kohei Nishino, Brian T. Layden, Hisakazu Kato, Hidesato Ogawa, Shinya Oki, Yukinori Okada, Yoshitaka Isaka, Hidetaka Kosako, Noriyuki Matsuda, Tamotsu Yoshimori, Shuhei Nakamura

Proceedings of the National Academy of Sciences　Vol. 121　No. 2　2024/01/03　Research paper (scientific journal)

Development of a prognostic risk score to predict early mortality in incident elderly Japanese hemodialysis patients.

Hirokazu Okada, Atsushi Ono, Koji Tomori, Tsutomu Inoue, Norio Hanafusa, Ken Sakai, Ichiei Narita, Toshiki Moriyama, Yoshitaka Isaka, Kei Fukami, Seiji Itano, Eiichiro Kanda, Naoki Kashihara

PloS one　Vol. 19　No. 4　2024　Research paper (scientific journal)

Clinical Impacts of Allograft Biopsy in Renal Transplant Recipients 10 Years or Longer After Transplantation.

Tomoko Namba-Hamano, Takayuki Hamano, Yohei Doi, Atsuko Hiraoka, Hiroaki Yonishi, Shinsuke Sakai, Atsushi Takahashi, Masayuki Mizui, Shigeaki Nakazawa, Kazuaki Yamanaka, Yoichi Kakuta, Ryoichi Imamura, Norio Nonomura, Yoshitaka Isaka

Transplant international : official journal of the European Society for Organ Transplantation　Vol. 37　p. 13022-13022　2024　Research paper (scientific journal)

d-Alanine Affects the Circadian Clock to Regulate Glucose Metabolism in Kidney.

Shinsuke Sakai, Youichi Tanaka, Yusuke Tsukamoto, Shihoko Kimura-Ohba, Atsushi Hesaka, Kenji Hamase, Chin-Ling Hsieh, Eiryo Kawakami, Hiraku Ono, Kotaro Yokote, Mitsuaki Yoshino, Daisuke Okuzaki, Hiroyo Matsumura, Atsuko Fukushima, Masashi Mita, Maiko Nakane, Masao Doi, Yoshitaka Isaka, Tomonori Kimura

Kidney360　2023/12/15　Research paper (scientific journal)

う蝕・歯科処置の際に腹膜透析関連腹膜炎を合併した2例

平岡 敦子, 北村 温美, 新澤 真紀, 松本 あゆみ, 門田 智香子, 河合 秀亮, 茂木 孝友, 平田 祐太郎, 酒井 晋介, 土井 洋平, 高橋 篤史, 水井 理之, 猪阪 善隆

大阪腹膜透析研究会会誌　Vol. 34-35　p. 19-23　2023/12

う蝕・歯科処置の際に腹膜透析関連腹膜炎を合併した2例

平岡 敦子, 北村 温美, 新澤 真紀, 松本 あゆみ, 門田 智香子, 河合 秀亮, 茂木 孝友, 平田 祐太郎, 酒井 晋介, 土井 洋平, 高橋 篤史, 水井 理之, 猪阪 善隆

大阪腹膜透析研究会会誌　Vol. 34-35　p. 19-23　2023/12

Dietary Omega-3 Polyunsaturated Fatty Acids and Amelioration of CKD: Possible Cellular Mechanisms.

Takeshi Yamamoto, Yoshitaka Isaka

Kidney360　Vol. 4　No. 12　p. 1661-1662　2023/12/01　Research paper (scientific journal)

The association between embedded catheter implantation and hospitalization costs for peritoneal dialysis initiation: a retrospective cohort study.

Maki Shinzawa, Ayumi Matsumoto, Harumi Kitamura, Yusuke Sakaguchi, Atsushi Takahashi, Isao Matsui, Masayuki Mizui, Ryohei Yamamoto, Yoshitaka Isaka

Clinical and experimental nephrology　2023/11/14　Research paper (scientific journal)

Spatiotemporally quantitative in vivo imaging of mitochondrial fatty acid β-oxidation at cellular-level resolution in mice

Ayumi Matsumoto, Isao Matsui, Shohei Uchinomiya, Yusuke Katsuma, Seiichi Yasuda, Hiroki Okushima, Atsuhiro Imai, Takeshi Yamamoto, Akio Ojida, Kazunori Inoue, Yoshitaka Isaka

American Journal of Physiology-Endocrinology and Metabolism　Vol. 325　No. 5　p. E552-E561　2023/11/01　Research paper (scientific journal)

FGF21 and autophagy coordinately counteract kidney disease progression during aging and obesity.

Satoshi Minami, Shinsuke Sakai, Takeshi Yamamoto, Yoshitsugu Takabatake, Tomoko Namba-Hamano, Atsushi Takahashi, Jun Matsuda, Hiroaki Yonishi, Jun Nakamura, Shihomi Maeda, Sho Matsui, Isao Matsui, Yoshitaka Isaka

Autophagy　2023/09/18　Research paper (scientific journal)

Demographics and treatment of patients with primary nephrotic syndrome in Japan using a national registry of clinical personal records.

Naoki Nakagawa, Tomonori Kimura, Ryuichi Sakate, Takehiko Wada, Kengo Furuichi, Hirokazu Okada, Yoshitaka Isaka, Ichiei Narita

Scientific reports　Vol. 13　No. 1　p. 14771-14771　2023/09/07　Research paper (scientific journal)

long-read next generation sequencerで診断し得た,ARPKDの1症例

貝森 淳哉, 河岡 孝征, 服部 洸輝, 朝比奈 悠太, 土井 洋平, 坂口 悠介, 永田 美保, 石原 康貴, 宮下 洋平, 朝野 仁裕, 猪阪 善隆

日本腎臓学会誌　Vol. 65　No. 6-W　p. 768-768　2023/09

腎疾患(FSGS)のみのphenotypeを呈した,MYH9変異を有する患者家系の解析

貝森 淳哉, 堀部 祐輝, 山中 和明, 河岡 孝征, 朝比奈 悠太, 服部 洸輝, 土井 洋平, 坂口 悠介, 永田 美保, 石原 康貴, 宮下 洋平, 朝野 仁裕, 猪阪 善隆

日本腎臓学会誌　Vol. 65　No. 6-W　p. 769-769　2023/09

Interstitial Eosinophilic Aggregates and Kidney Outcome in Patients with CKD

Koki Hattori, Yusuke Sakaguchi, Tatsufumi Oka, Yuta Asahina, Takayuki Kawaoka, Ryohei Yamamoto, Isao Matsui, Masayuki Mizui, Jun-Ya Kaimori, Yoshitaka Isaka

Clinical Journal of American Society of Nephrology　2023/09　Research paper (scientific journal)

Demographics and treatment of patients with primary membranoproliferative glomerulonephritis in Japan using a national registry of clinical personal records.

Naoki Nakagawa, Tomonori Kimura, Ryuichi Sakate, Yoshitaka Isaka, Ichiei Narita

Clinical and experimental nephrology　2023/07/29　Research paper (scientific journal)

D-Serine as a sensor and effector of the kidney.

Tomonori Kimura, Shinsuke Sakai, Yoshitaka Isaka

Clinical and experimental nephrology　2023/07/27　Research paper (scientific journal)

Blood levels of d-amino acids reflect the clinical course of COVID-19.

Shihoko Kimura-Ohba, Yoshitsugu Takabatake, Atsushi Takahashi, Yoko Tanaka, Shinsuke Sakai, Yoshitaka Isaka, Tomonori Kimura

Biochemistry and biophysics reports　Vol. 34　p. 101452-101452　2023/07　Research paper (scientific journal)

Mediators between canagliflozin and renoprotection vary depending on patient characteristics: Insights from the <scp>CREDENCE</scp> trial

Yohei Doi, Takayuki Hamano, Satoshi Yamaguchi, Yusuke Sakaguchi, Jun‐Ya Kaimori, Yoshitaka Isaka

Diabetes, Obesity and Metabolism　2023/06/29　Research paper (scientific journal)

【腎疾患研究のためのメタバース構築】リピドーム解析による腎臓病の理解

山本 毅士, 中村 隼, 高橋 政友, 和泉 自泰, 馬場 健史, 猪阪 善隆

腎臓内科　Vol. 17　No. 6　p. 688-699　2023/06　Research paper (scientific journal)

Albumin Clearance as a Novel Predictor of Relapse in Adults with Minimal Change Nephrotic Syndrome.

Ryohei Yamamoto, Yoshitaka Isaka

Kidney360　Vol. 4　No. 6　2023/06/01　Research paper (scientific journal)

D-Asparagine is an Ideal Endogenous Molecule for Measuring the Glomerular Filtration Rate.

Ayumu Taniguchi, Masataka Kawamura, Shinsuke Sakai, Shihoko Kimura-Ohba, Yoko Tanaka, Shota Fukae, Ryo Tanaka, Shigeaki Nakazawa, Kazuaki Yamanaka, Masaru Horio, Shiro Takahara, Norio Nonomura, Yoshitaka Isaka, Ryoichi Imamura, Tomonori Kimura

Kidney international reports　Vol. 8　No. 6　p. 1192-1200　2023/06　Research paper (scientific journal)

Association of Longitudinal B-Type Natriuretic Peptide Monitoring With Kidney Failure in Patients With CKD: A Cohort Study

Tatsufumi Oka, Yusuke Sakaguchi, Koki Hattori, Yuta Asahina, Sachio Kajimoto, Wendy McCallum, Hocine Tighiouart, Mark J. Sarnak, Jun-Ya Kaimori, Yoshitaka Isaka

American Journal of Kidney Diseases　2023/06　Research paper (scientific journal)

ポドサイト障害モデルと虚血再灌流障害モデルに共通してCKD進行に関与する細胞群の同定

今井淳裕, 松井功, 奥嶋拓樹, 勝間勇介, 安田聖一, 松本あゆみ, 南聡, 山本毅士, 井上和則, 猪阪善隆

日本腎臓学会誌　Vol. 65　No. 3　2023/05/23　Research paper (scientific journal)

Diabetic nephropathy with marked extra-capillary cell proliferation: a case report.

Madoka Morimoto, Tomoko Namba-Hamano, Shoki Notsu, Yukimasa Iwata, Yumiko Yasuhara, Masafumi Yamato, Yoshitaka Isaka

BMC nephrology　Vol. 24　No. 1　p. 139-139　2023/05/22　Research paper (scientific journal)

Association between serum iron markers, iron supplementation, and cardiovascular morbidity in pre-dialysis chronic kidney disease.

Takeshi Hasegawa, Takahiro Imaizumi, Takayuki Hamano, Kenta Murotani, Naohiko Fujii, Hirotaka Komaba, Masahiko Ando, Shoichi Maruyama, Masaomi Nangaku, Kosaku Nitta, Hideki Hirakata, Yoshitaka Isaka, Takashi Wada, Masafumi Fukagawa

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association　2023/05/18　Research paper (scientific journal)

糸球体腎炎up to date 膜性増殖性糸球体腎炎とC3腎症の診断・治療

中川 直樹, 水野 正司, 猪阪 善隆

日本腎臓学会誌　Vol. 65　No. 3　p. 216-216　2023/05

血液透析患者における経カテーテル的大動脈弁置換術後の弁構造劣化の予測因子と生命予後の検討(続報)

増山 慧, 水井 理之, 前田 孝一, 島村 和男, 坂口 悠介, 坂田 泰史, 宮川 繁, 猪阪 善隆

日本透析医学会雑誌　Vol. 56　No. Suppl.1　p. 579-579　2023/05

腎間質好酸球集簇は腎予後予測能を改善する

服部 洸輝, 坂口 悠介, 河岡 孝征, 朝比奈 悠太, 梶本 幸男, 貝森 淳哉, 松井 功, 水井 理之, 猪阪 善隆

日本腎臓学会誌　Vol. 65　No. 3　p. 275-275　2023/05

患者背景によりCanagliflozinの腎保護効果媒介因子・割合は異なる CREDENCE trial

土井 洋平, 濱野 高行, 猪阪 善隆

日本腎臓学会誌　Vol. 65　No. 3　p. 287-287　2023/05

腎線維化のメカニズム 尿細管細胞の関与

猪阪 善隆, 南 聡, 山本 毅士

日本腎臓学会誌　Vol. 65　No. 3　p. 187-187　2023/05

MondoAはTFEB活性化を介したミトコンドリア生合成によりAKIからCKDへの進展を抑制する

前田 志穂美, 酒井 晋介, 山本 毅士, 高橋 篤史, 難波 倫子, 松田 潤, 南 聡, 中村 隼, 松井 翔, 島田 直幸, 高畠 義嗣, 柳田 素子, 猪阪 善隆

日本腎臓学会誌　Vol. 65　No. 3　p. 247-247　2023/05

FGF21とオートファジーは協調的に加齢や肥満による腎臓病進展に対抗する

山本 毅士, 南 聡, 酒井 晋介, 高橋 篤史, 難波 倫子, 松田 潤, 余西 洋明, 中村 隼, 前田 志穂美, 松井 翔, 河合 秀亮, 高畠 義嗣, 猪阪 善隆

日本腎臓学会誌　Vol. 65　No. 3　p. 253-253　2023/05

エンパグリフロジンはメガリン介在性アルブミン 脂肪酸毒性に伴うオートファジー停滞を解消し腎保護に働く

松井 翔, 山本 毅士, 高畠 義嗣, 高橋 篤史, 難波 倫子, 松田 潤, 南 聡, 酒井 晋介, 中村 隼, 前田 志穂美, 柳田 素子, 猪阪 善隆

日本腎臓学会誌　Vol. 65　No. 3　p. 293-293　2023/05

D-アスパラギンは糸球体ろ過量測定に理想的な内因性分子である

木村 友則, 谷口 歩, 今村 亮一, 高原 史郎, 堀尾 勝, 酒井 晋介, 猪阪 善隆

日本腎臓学会誌　Vol. 65　No. 3　p. 257-257　2023/05

D-アラニンは重症インフルエンザ感染症とCOVID-19のバイオマーカーであり,かつ治療応用性がある

木村 友則, 浅賀 正充, 内海 大和, 保富 康宏, 木村 志保子, 高畠 義嗣, 高橋 篤史, 猪阪 善隆

日本腎臓学会誌　Vol. 65　No. 3　p. 327-327　2023/05

D-アスパラギンは糸球体ろ過量測定に理想的な内因性分子である

木村 友則, 谷口 歩, 今村 亮一, 高原 史郎, 堀尾 勝, 酒井 晋介, 猪阪 善隆

日本腎臓学会誌　Vol. 65　No. 3　p. 257-257　2023/05

D-アラニンは重症インフルエンザ感染症とCOVID-19のバイオマーカーであり,かつ治療応用性がある

木村 友則, 浅賀 正充, 内海 大和, 保富 康宏, 木村 志保子, 高畠 義嗣, 高橋 篤史, 猪阪 善隆

日本腎臓学会誌　Vol. 65　No. 3　p. 327-327　2023/05

Obesity-related proximal tubulopathy: an emerging threat to kidney health.

Takeshi Yamamoto, Jun Nakamura, Yoshitsugu Takabatake, Yoshitaka Isaka

Autophagy Reports.　Vol. 2　No. 1　2023/04/10

Hepatic phosphate uptake and subsequent nerve-mediated phosphaturia are crucial for phosphate homeostasis following portal vein passage of phosphate in rats

Seiichi Yasuda, Kazunori Inoue, Isao Matsui, Ayumi Matsumoto, Yusuke Katsuma, Hiroki Okushima, Atsuhiro Imai, Yusuke Sakaguchi, Jun-ya Kaimori, Ryohei Yamamoto, Masayuki Mizui, Yoshitaka Isaka

Scientific Reports　Vol. 13　No. 1　2023/04/08　Research paper (scientific journal)

A Case Report of a Kidney Transplant Recipient With Organizing Pneumonia After Graft Loss

Sho Matsui, Tomoko Namba-Hamano, Shihomi Maeda, Jun Nakamura, Atsushi Takahashi, Jun-Ya Kaimori, Shota Fukae, Ryo Tanaka, Ayumu Taniguchi, Shigeaki Nakazawa, Kazuaki Yamanaka, Ryoichi Imamura, Norio Nonomura, Yoshitaka Isaka

Transplantation Proceedings　2023/04　Research paper (scientific journal)

A Dose-Dependent Association between Alcohol Consumption and Incidence of Proteinuria and Low Glomerular Filtration Rate: A Systematic Review and Meta-Analysis of Cohort Studies

Ryohei Yamamoto, Qinyan Li, Naoko Otsuki, Maki Shinzawa, Makoto Yamaguchi, Minako Wakasugi, Yasuyuki Nagasawa, Yoshitaka Isaka

Nutrients　Vol. 15　No. 7　p. 1592-1592　2023/03/25　Research paper (scientific journal)

Alcohol Consumption and a Decline in Glomerular Filtration Rate: The Japan Specific Health Checkups Study

Yoshiki Kimura, Ryohei Yamamoto, Maki Shinzawa, Katsunori Aoki, Ryohei Tomi, Shingo Ozaki, Ryuichi Yoshimura, Akihiro Shimomura, Hirotsugu Iwatani, Yoshitaka Isaka, Kunitoshi Iseki, Kazuhiko Tsuruya, Shouichi Fujimoto, Ichiei Narita, Tsuneo Konta, Masahide Kondo, Masato Kasahara, Yugo Shibagaki, Koichi Asahi, Tsuyoshi Watanabe, Kunihiro Yamagata, Toshiki Moriyama

Nutrients　Vol. 15　No. 6　p. 1540-1540　2023/03/22　Research paper (scientific journal)

Autophagy and kidney aging.

Satoshi Minami, Takeshi Yamamoto, Hitomi Yamamoto-Imoto, Yoshitaka Isaka, Maho Hamasaki

Progress in biophysics and molecular biology　Vol. 179　p. 10-15　2023/02/25　Research paper (scientific journal)

Plant-Dominant Low Protein Diet: A Potential Alternative Dietary Practice for Patients with Chronic Kidney Disease

Yusuke Sakaguchi, Jun-Ya Kaimori, Yoshitaka Isaka

Nutrients　Vol. 15　No. 4　p. 1002-1002　2023/02/16　Research paper (scientific journal)

Decreased thymic output predicts progression of chronic kidney disease

Kenichiro Iio, Daijiro Kabata, Rei Iio, Shinichi Shibamoto, Yuuki Watanabe, Masashi Morita, Yosuke Imai, Masaki Hatanaka, Hiroki Omori, Yoshitaka Isaka

IMMUNITY & AGEING　Vol. 20　No. 1　2023/02　Research paper (scientific journal)

Mitigating Drug-Target-Drug Complexes in Patients With Paroxysmal Nocturnal Hemoglobinuria Who Switch C5 Inhibitors.

Jun-Ichi Nishimura, Antoine Soubret, Noriko Arase, Simon Buatois, Masaki Hotta, Jean-Eric Charoin, Yoshikazu Ito, Sasha Sreckovic, Hiroyuki Takamori, Christoph Bucher, Yasutaka Ueda, Jules Hernández-Sánchez, Keisuke Gotanda, Gregor Jordan, Kenji Shinomiya, Julia Ramos, Jin Seok Kim, Jens Panse, Régis Peffault de Latour, Alexander Röth, Eiichi Morii, Hubert Schrezenmeier, Yoshitaka Isaka, Simona Sica, Yuzuru Kanakura, Sung-Soo Yoon, Taroh Kinoshita, Ido Paz-Priel, Alexandre Sostelly

Clinical pharmacology and therapeutics　Vol. 113　No. 4　p. 904-915　2023/01/20　Research paper (scientific journal)

TFEB-mediated lysosomal exocytosis alleviates high fat diet-induced lipotoxicity in the kidney.

Jun Nakamura, Takeshi Yamamoto, Yoshitsugu Takabatake, Tomoko Namba-Hamano, Satoshi Minami, Atsushi Takahashi, Jun Matsuda, Shinsuke Sakai, Hiroaki Yonishi, Shihomi Maeda, Sho Matsui, Isao Matsui, Takayuki Hamano, Masatomo Takahashi, Maiko Goto, Yoshihiro Izumi, Takeshi Bamba, Miwa Sasai, Masahiro Yamamoto, Taiji Matsusaka, Fumio Niimura, Motoko Yanagita, Shuhei Nakamura, Tamotsu Yoshimori, Andrea Ballabio, Yoshitaka Isaka

JCI insight　Vol. 8　No. 4　2023/01/17　Research paper (scientific journal)

Referral pattern to nephrologist and prognosis in diabetic kidney disease patients: Single center retrospective cohort study.

Yukimasa Iwata, Terumasa Hayashi, Hiroki Okushima, Ryuta Uwatoko, Taisuke Takatsuka, Daisuke Yoshimura, Tomohiro Kawamura, Rei Iio, Yoshiyasu Ueda, Tatsuya Shoji, Yoshitaka Isaka

PloS one　Vol. 18　No. 2　2023　Research paper (scientific journal)

A Randomized Controlled Trial of Whole-Body Vibration on Gait Ability and Balance among Older Hemodialysis Patients.

Yuta Asahina, Yusuke Sakaguchi, Sachio Kajimoto, Koki Hattori, Tatsufumi Oka, Jun-Ya Kaimori, Naoki Kashihara, Yoshitaka Isaka

Clinical journal of the American Society of Nephrology : CJASN　Vol. 18　No. 1　p. 84-90　2023/01/01　Research paper (scientific journal)

Preoperative hypomagnesemia as a possible predictive factor for postoperative increase of transvalvular pressure gradient in hemodialysis patients treated with transcatheter aortic valve implantation.

Satoshi Masuyama, Masayuki Mizui, Koichi Maeda, Kazuo Shimamura, Yusuke Sakaguchi, Masashi Morita, Toru Kuratani, Isamu Mizote, Daisuke Nakamura, Yasushi Sakata, Yoshiki Sawa, Shigeru Miyagawa, Yoshitaka Isaka

Renal failure　Vol. 44　No. 1　p. 1083-1089　2022/12　Research paper (scientific journal)

Establishment and clinical application of SARS-CoV-2 catch column

Yoshitaka Isaka, Taku Yoshiya, Chikako Ono, Akinori Uchiyama, Haruhiko Hirata, Shigeto Hamaguchi, Satoshi Kutsuna, Yoshitsugu Takabatake, Ryotaro Saita, Tomomi Yamada, Atsushi Takahashi, Masaya Yamato, Yukie Nohara, Shugo Tsuda, Itsuki Anzai, Tomonori Kimura, Yoshito Takeda, Kazunori Tomono, Yoshiharu Matsuura

Clinical and Experimental Nephrology　Vol. 27　No. 3　p. 279-287　2022/11/07　Research paper (scientific journal)

T cell function and diseases-1(Disease models and SARS-CoV-2)(A selective PPARα modulator-mediated metabolic manipulation ameliorates autoimmunity by limiting glutaminolysis in Th17 cells)

Masuyama Satoshi, Mizui Masayuki, Morita Masashi, Okuno Tatsusada, Isaka Yoshitaka

日本免疫学会総会・学術集会記録　Vol. 51　No. Proceedings　p. WS10-P　2022/11　Research paper (scientific journal)

Author Correction: LC3 lipidation is essential for TFEB activation during the lysosomal damage response to kidney injury.

Shuhei Nakamura, Saki Shigeyama, Satoshi Minami, Takayuki Shima, Shiori Akayama, Tomoki Matsuda, Alessandra Esposito, Gennaro Napolitano, Akiko Kuma, Tomoko Namba-Hamano, Jun Nakamura, Kenichi Yamamoto, Miwa Sasai, Ayaka Tokumura, Mika Miyamoto, Yukako Oe, Toshiharu Fujita, Seigo Terawaki, Atsushi Takahashi, Maho Hamasaki, Masahiro Yamamoto, Yukinori Okada, Masaaki Komatsu, Takeharu Nagai, Yoshitsugu Takabatake, Haoxing Xu, Yoshitaka Isaka, Andrea Ballabio, Tamotsu Yoshimori

Nature cell biology　Vol. 24　No. 11　p. 1677-1679　2022/11　Research paper (scientific journal)

d-Alanine as a biomarker and a therapeutic option for severe influenza virus infection and COVID-19.

Shihoko Kimura-Ohba, Masamitsu N Asaka, Daichi Ustumi, Yoshitsugu Takabatake, Atsushi Takahashi, Yasuhiro Yasutomi, Yoshitaka Isaka, Tomonori Kimura

Biochimica et biophysica acta. Molecular basis of disease　Vol. 1869　No. 1　p. 166584-166584　2022/10/21　Research paper (scientific journal)

D-アミノ酸測定を用いた新たな腎機能評価法の確立

谷口 歩, 川村 正隆, 木村 友則, 今村 亮一, 中澤 成晃, 山中 和明, 猪阪 善隆, 高原 史郎, 野々村 祝夫

移植　Vol. 57　No. 総会臨時　p. 373-373　2022/10　Research paper (scientific journal)

Acute Kidney Injury and Remission of Proteinuria in Minimal Change Disease.

Ryohei Yamamoto, Enyu Imai, Shoichi Maruyama, Hitoshi Yokoyama, Hitoshi Sugiyama, Asami Takeda, Shunya Uchida, Tatsuo Tsukamoto, Kazuhiko Tsuruya, Yasuhiro Akai, Kosaku Nitta, Megumu Fukunaga, Hiroki Hayashi, Tatsuya Shoji, Kosuke Masutani, Tsuneo Konta, Ritsuko Katafuchi, Saori Nishio, Takashi Wada, Shunsuke Goto, Hirofumi Tamai, Arimasa Shirasaki, Kojiro Nagai, Tomoya Nishino, Kunihiro Yamagata, Junichiro J Kazama, Keiju Hiromura, Hideo Yasuda, Tadashi Sofue, Shouichi Fujimoto, Makoto Mizutani, Tomohiko Naruse, Takeyuki Hiramatsu, Kunio Morozumi, Hiroshi Sobajima, Yosuke Saka, Eiji Ishimura, Takafumi Ito, Daisuke Ichikawa, Takashi Shigematsu, Hiroshi Sato, Ichiei Narita, Isaka Yoshitaka

Kidney international reports　Vol. 7　No. 10　p. 2283-2288　2022/10　Research paper (scientific journal)

A heterozygous LAMA5 variant may contribute to slowly progressive, vinculin-enhanced familial FSGS and pulmonary defects

Jun-Ya Kaimori, Yamato Kikkawa, Daisuke Motooka, Tomoko Namba-Hamano, Ayako Takuwa, Atsuko Imai-Okazaki, Kaori Kobayashi, Arisa Tanigawa, Yuko Kotani, Yoshihiro Uno, Kazuto Yoshimi, Koki Hattori, Yuta Asahina, Sachio Kajimoto, Yohei Doi, Tatsufumi Oka, Yusuke Sakaguchi, Tomoji Mashimo, Kiyotoshi Sekiguchi, Akihiro Nakaya, Motoyoshi Nomizu, Yoshitaka Isaka

JCI Insight　Vol. 7　No. 23　2022/09/29　Research paper (scientific journal)

Effects of alfacalcidol on cardiovascular outcomes according to alkaline phosphatase levels in the J-DAVID trial.

Tatsufumi Oka, Yusuke Sakaguchi, Yoshitaka Isaka, Haruka Ishii, Daijiro Kabata, Ayumi Shintani, Shinya Nakatani, Tomoaki Morioka, Katsuhito Mori, Masaaki Inaba, Masanori Emoto, Tetsuo Shoji

Scientific reports　Vol. 12　No. 1　p. 15463-15463　2022/09/14　Research paper (scientific journal)

Deep learning analysis of clinical course of primary nephrotic syndrome: Japan Nephrotic Syndrome Cohort Study (JNSCS).

Tomonori Kimura, Ryohei Yamamoto, Mitsuaki Yoshino, Ryuichi Sakate, Enyu Imai, Shoichi Maruyama, Hitoshi Yokoyama, Hitoshi Sugiyama, Kosaku Nitta, Tatsuo Tsukamoto, Shunya Uchida, Asami Takeda, Toshinobu Sato, Takashi Wada, Hiroki Hayashi, Yasuhiro Akai, Megumu Fukunaga, Kazuhiko Tsuruya, Kosuke Masutani, Tsuneo Konta, Tatsuya Shoji, Takeyuki Hiramatsu, Shunsuke Goto, Hirofumi Tamai, Saori Nishio, Kojiro Nagai, Kunihiro Yamagata, Hideo Yasuda, Shizunori Ichida, Tomohiko Naruse, Tomoya Nishino, Hiroshi Sobajima, Toshiyuki Akahori, Takafumi Ito, Yoshio Terada, Ritsuko Katafuchi, Shouichi Fujimoto, Hirokazu Okada, Tetsushi Mimura, Satoshi Suzuki, Yosuke Saka, Tadashi Sofue, Kiyoki Kitagawa, Yoshiro Fujita, Makoto Mizutani, Naoki Kashihara, Hiroshi Sato, Ichiei Narita, Yoshitaka Isaka

Clinical and experimental nephrology　Vol. 26　No. 12　p. 1170-1179　2022/08/12　Research paper (scientific journal)

生活指導に難渋したクラインフェルター症候群合併腹膜透析症例

中山 尋文, 北岡 太一, 宮田 京, 武鑓 真司, 中野 由佳子, 大幡 泰久, 藤原 誠, 窪田 拓生, 北村 温美, 猪阪 善隆, 大薗 恵一

大阪腹膜透析研究会会誌　Vol. 33　p. 25-28　2022/08　Research paper (scientific journal)

長期間の腹膜透析管理を行った巣状分節性糸球体硬化症の一例

北岡 太一, 宮田 京, 山田 知絵子, 中山 尋文, 藤原 誠, 大幡 泰久, 窪田 拓生, 大薗 恵一, 北村 温美, 増山 慧, 高橋 篤史, 猪阪 善隆, 今村 亮一, 阿部 豊文, 加藤 大悟, 野々村 祝夫

大阪腹膜透析研究会会誌　Vol. 33　p. 29-34　2022/08　Research paper (scientific journal)

Predictors of early remission of proteinuria in adult patients with minimal change disease: a retrospective cohort study.

Ryohei Yamamoto, Enyu Imai, Shoichi Maruyama, Hitoshi Yokoyama, Hitoshi Sugiyama, Asami Takeda, Shunya Uchida, Tatsuo Tsukamoto, Kazuhiko Tsuruya, Yasuhiro Akai, Kosaku Nitta, Megumu Fukunaga, Hiroki Hayashi, Kosuke Masutani, Takashi Wada, Tsuneo Konta, Ritsuko Katafuchi, Saori Nishio, Shunsuke Goto, Hirofumi Tamai, Arimasa Shirasaki, Tatsuya Shoji, Kojiro Nagai, Tomoya Nishino, Kunihiro Yamagata, Junichiro J Kazama, Keiju Hiromura, Hideo Yasuda, Makoto Mizutani, Tomohiko Naruse, Takeyuki Hiramatsu, Kunio Morozumi, Hiroshi Sobajima, Yosuke Saka, Eiji Ishimura, Daisuke Ichikawa, Takashi Shigematsu, Tadashi Sofue, Shouichi Fujimoto, Takafumi Ito, Hiroshi Sato, Ichiei Narita, Yoshitaka Isaka

Scientific reports　Vol. 12　No. 1　p. 9782-9782　2022/06/13　Research paper (scientific journal)

p53とオートファジーの協調作用によってDNA損傷と細胞老化関連分泌現象が抑制され、腎臓の加齢が遅延する(Cooperative action of p53 and autophagy delays kidney aging by suppressing DNA damage and the senescence-associated secretory phenotype)

山本 毅士, 南 聡, 高畠 義嗣, 猪阪 善隆

日本抗加齢医学会総会プログラム・抄録集　Vol. 22回　p. 208-208　2022/06　Research paper (scientific journal)

p53とオートファジーの協調作用によってDNA損傷と細胞老化関連分泌現象が抑制され、腎臓の加齢が遅延する(Cooperative action of p53 and autophagy delays kidney aging by suppressing DNA damage and the senescence-associated secretory phenotype)

山本 毅士, 南 聡, 高畠 義嗣, 猪阪 善隆

日本抗加齢医学会総会プログラム・抄録集　Vol. 22回　p. 208-208　2022/06　Research paper (scientific journal)

New-onset and relapse of nephrotic syndrome following COVID-19 vaccination: a questionnaire survey in Japan.

Naoki Nakagawa, Shoichi Maruyama, Naoki Kashihara, Ichiei Narita, Yoshitaka Isaka

Clinical and experimental nephrology　Vol. 26　No. 9　p. 909-916　2022/05/15　Research paper (scientific journal)

Alkali therapy for prevention of acute kidney injury in rhabdomyolysis.

Jun-Ya Kaimori, Yusuke Sakaguchi, Yoshitaka Isaka

Kidney research and clinical practice　Vol. 41　No. 5　p. 521-523　2022/05/09　Research paper (scientific journal)

Initiation of Renin-Angiotensin System Inhibitors and the Incidence of First Complete Remission in Patients with Primary Nephrotic Syndrome: A Nationwide Cohort Study

Sayaka Shimizu, Kakuya Niihata, Hiroki Nishiwaki, Yugo Shibagaki, Ryohei Yamamoto, Kosaku Nitta, Tatsuo Tsukamoto, Shunya Uchida, Asami Takeda, Hirokazu Okada, Ichiei Narita, Yoshitaka Isaka, Noriaki Kurita

2022/05/02　Research paper (scientific journal)

エンパグリフロジンは脂肪酸毒性軽減とオートファジー停滞解消を介して腎保護に働く

松井 翔, 山本 毅士, 高畠 義嗣, 高橋 篤史, 難波 倫子, 松田 潤, 南 聡, 酒井 晋介, 余西 洋明, 中村 隼, 前田 志穂美, 柳田 素子, 猪阪 善隆

日本腎臓学会誌　Vol. 64　No. 3　p. 221-221　2022/05

糖尿病性腎臓病におけるオートファジー不全と脂質代謝異常はフェロトーシス亢進を介して腎障害を悪化させる

松井 翔, 山本 毅士, 高畠 義嗣, 高橋 篤史, 難波 倫子, 松田 潤, 南 聡, 酒井 晋介, 余西 洋明, 中村 隼, 前田 志穂美, 新村 文男, 松阪 泰二, 猪阪 善隆

日本腎臓学会誌　Vol. 64　No. 3　p. 239-239　2022/05

TFEBは尿中へのリン脂質排出促進により肥満関連尿細管症に対して保護的に働く

中村 隼, 山本 毅士, 高畠 義嗣, 難波 倫子, 南 聡, 高橋 篤史, 松田 潤, 酒井 晋介, 前田 志穂美, 松井 翔, 新村 文男, 松阪 泰二, 猪阪 善隆

日本腎臓学会誌　Vol. 64　No. 3　p. 245-245　2022/05

MondoAはRubiconを介して尿細管のオートファジー活性を制御し、腎保護的に働く

前田 志穂美, 酒井 晋介, 高畠 義嗣, 高橋 篤史, 難波 倫子, 山本 毅士, 松田 潤, 南 聡, 中村 隼, 松井 翔, 新村 文男, 柳田 素子, 松阪 泰二, 猪阪 善隆

日本腎臓学会誌　Vol. 64　No. 3　p. 246-246　2022/05

近位尿細管におけるp53とオートファジーはSASP(老化関連分泌表現型)を協調的に抑制し腎老化を抑制する

南 聡, 山本 毅, 高畠 義嗣, 高橋 篤史, 難波 倫子, 松田 潤, 酒井 晋介, 中村 隼, 前田 志穂美, 松井 翔, 新村 文男, 松阪 泰二, 猪阪 善隆

日本腎臓学会誌　Vol. 64　No. 3　p. 253-253　2022/05

TRPC3/6阻害薬L-862はリポファジーを介した脂質代謝改善により急性腎障害を軽減する

山本 毅士, 余西 洋明, 高畠 義嗣, 松井 翔, 中村 隼, 難波 倫子, 高橋 篤史, 松田 潤, 南 聡, 酒井 晋介, 前田 志穂美, 永田 龍, 猪阪 善隆

日本腎臓学会誌　Vol. 64　No. 3　p. 260-260　2022/05

深層学習による原発性ネフローゼ症候群の自然歴の検討 日本ネフローゼ症候群コホート研究

木村 友則, 吉野 満昭, 坂手 龍一, 山本 陵平, 新沢 真紀, 猪阪 善隆, 成田 一衛

日本腎臓学会誌　Vol. 64　No. 3　p. 277-277　2022/05　Research paper (scientific journal)

D-セリンクリアランスによる糸球体濾過量の測定

部坂 篤, 川村 正隆, 谷口 歩, 阿部 豊文, 堀尾 勝, 高原 史郎, 野々村 祝夫, 今村 亮一, 猪阪 善隆, 木村 友則

日本腎臓学会誌　Vol. 64　No. 3　p. 301-301　2022/05　Research paper (scientific journal)

平日の短時間睡眠者における睡眠負債とCKD

尾崎 晋吾, 山本 陵平, 松下 泰祐, 松村 雄一朗, 芦村 龍一, 新沢 真紀, 猪阪 善隆, 守山 敏樹

日本腎臓学会誌　Vol. 64　No. 3　p. 249-249　2022/05　Research paper (scientific journal)

エンパグリフロジンは脂肪酸毒性軽減とオートファジー停滞解消を介して腎保護に働く

松井 翔, 山本 毅士, 高畠 義嗣, 高橋 篤史, 難波 倫子, 松田 潤, 南 聡, 酒井 晋介, 余西 洋明, 中村 隼, 前田 志穂美, 柳田 素子, 猪阪 善隆

日本腎臓学会誌　Vol. 64　No. 3　p. 221-221　2022/05　Research paper (scientific journal)

糖尿病性腎臓病におけるオートファジー不全と脂質代謝異常はフェロトーシス亢進を介して腎障害を悪化させる

松井 翔, 山本 毅士, 高畠 義嗣, 高橋 篤史, 難波 倫子, 松田 潤, 南 聡, 酒井 晋介, 余西 洋明, 中村 隼, 前田 志穂美, 新村 文男, 松阪 泰二, 猪阪 善隆

日本腎臓学会誌　Vol. 64　No. 3　p. 239-239　2022/05　Research paper (scientific journal)

TFEBは尿中へのリン脂質排出促進により肥満関連尿細管症に対して保護的に働く

中村 隼, 山本 毅士, 高畠 義嗣, 難波 倫子, 南 聡, 高橋 篤史, 松田 潤, 酒井 晋介, 前田 志穂美, 松井 翔, 新村 文男, 松阪 泰二, 猪阪 善隆

日本腎臓学会誌　Vol. 64　No. 3　p. 245-245　2022/05　Research paper (scientific journal)

TRPC3/6阻害薬L-862はリポファジーを介した脂質代謝改善により急性腎障害を軽減する

山本 毅士, 余西 洋明, 高畠 義嗣, 松井 翔, 中村 隼, 難波 倫子, 高橋 篤史, 松田 潤, 南 聡, 酒井 晋介, 前田 志穂美, 永田 龍, 猪阪 善隆

日本腎臓学会誌　Vol. 64　No. 3　p. 260-260　2022/05　Research paper (scientific journal)

Time to remission of proteinuria and incidence of relapse in patients with steroid-sensitive minimal change disease and focal segmental glomerulosclerosis: the Japan Nephrotic Syndrome Cohort Study.

Ryohei Yamamoto, Enyu Imai, Shoichi Maruyama, Hitoshi Yokoyama, Hitoshi Sugiyama, Asami Takeda, Tatsuo Tsukamoto, Shunya Uchida, Kazuhiko Tsuruya, Tatsuya Shoji, Hiroki Hayashi, Yasuhiro Akai, Megumu Fukunaga, Tsuneo Konta, Saori Nishio, Shunsuke Goto, Hirofumi Tamai, Kojiro Nagai, Ritsuko Katafuchi, Kosuke Masutani, Takashi Wada, Tomoya Nishino, Arimasa Shirasaki, Hiroshi Sobajima, Kosaku Nitta, Kunihiro Yamagata, Junichiro J Kazama, Keiju Hiromura, Hideo Yasuda, Makoto Mizutani, Toshiyuki Akahori, Tomohiko Naruse, Takeyuki Hiramatsu, Kunio Morozumi, Tetsushi Mimura, Yosuke Saka, Eiji Ishimura, Hajime Hasegawa, Daisuke Ichikawa, Takashi Shigematsu, Hiroshi Sato, Ichiei Narita, Yoshitaka Isaka

Journal of nephrology　Vol. 35　No. 4　p. 1135-1144　2022/05　Research paper (scientific journal)

Time-updated anion gap and cardiovascular events in advanced chronic kidney disease: a cohort study.

Yuta Asahina, Yusuke Sakaguchi, Sachio Kajimoto, Koki Hattori, Yohei Doi, Tatsufumi Oka, Jun-Ya Kaimori, Yoshitaka Isaka

Clinical kidney journal　Vol. 15　No. 5　p. 929-936　2022/05　Research paper (scientific journal)

Biopsy-proven CKD etiology and outcomes: Chronic Kidney Disease Japan Cohort (CKD-JAC) study.

Takayuki Hamano, Takahiro Imaizumi, Takeshi Hasegawa, Naohiko Fujii, Hirotaka Komaba, Masahiko Ando, Masaomi Nangaku, Kosaku Nitta, Hideki Hirakata, Yoshitaka Isaka, Takashi Wada, Shoichi Maruyama, Masafumi Fukagawa

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association　2022/03/22　Research paper (scientific journal)

TFEBはリソソーマルエクソサイトーシスを介したリン脂質蓄積抑制により腎保護的に働く

山本 毅士, 中村 隼, 高畠 義嗣, 猪阪 善隆

肥満研究　Vol. 27　No. Suppl.　p. 326-326　2022/03　Research paper (scientific journal)

FGF21はオートファジーと協調的に肥満関連腎尿細管症(Obesity-Related Tubulopathy)に対抗する

山本 毅士, 酒井 晋介, 高畠 義嗣, 猪阪 善隆

肥満研究　Vol. 27　No. Suppl.　p. 326-326　2022/03　Research paper (scientific journal)

Mineralocorticoid Receptor Antagonist Use and Hard Renal Outcomes in Real-World Patients With Chronic Kidney Disease.

Tatsufumi Oka, Yusuke Sakaguchi, Koki Hattori, Yuta Asahina, Sachio Kajimoto, Yohei Doi, Jun-Ya Kaimori, Yoshitaka Isaka

Hypertension (Dallas, Tex. : 1979)　Vol. 79　No. 3　p. 679-689　2022/03　Research paper (scientific journal)

Age-associated decline of MondoA drives cellular senescence through impaired autophagy and mitochondrial homeostasis.

Hitomi Yamamoto-Imoto, Satoshi Minami, Tatsuya Shioda, Yurina Yamashita, Shinsuke Sakai, Shihomi Maeda, Takeshi Yamamoto, Shinya Oki, Mizuki Takashima, Tadashi Yamamuro, Kyosuke Yanagawa, Ryuya Edahiro, Miki Iwatani, Mizue So, Ayaka Tokumura, Toyofumi Abe, Ryoichi Imamura, Norio Nonomura, Yukinori Okada, Donald E Ayer, Hidesato Ogawa, Eiji Hara, Yoshitsugu Takabatake, Yoshitaka Isaka, Shuhei Nakamura, Tamotsu Yoshimori

Cell reports　Vol. 38　No. 9　p. 110444-110444　2022/03/01　Research paper (scientific journal)

Intradialytic hypotension and objectively measured physical activity among patients on hemodialysis.

Koki Hattori, Yusuke Sakaguchi, Sachio Kajimoto, Yuta Asahina, Yohei Doi, Tatsufumi Oka, Jun-Ya Kaimori, Yoshitaka Isaka

Journal of nephrology　Vol. 35　No. 5　p. 1409-1418　2022/01/16　Research paper (scientific journal)

Diagnosing metabolic acidosis in chronic kidney disease: importance of blood pH and serum anion gap.

Jun-Ya Kaimori, Yusuke Sakaguchi, Sachio Kajimoto, Yuta Asahina, Tatsufumi Oka, Koki Hattori, Yohei Doi, Yoshitaka Isaka

Kidney research and clinical practice　Vol. 41　No. 3　p. 288-297　2022/01/10　Research paper (scientific journal)

Present status of renal replacement therapy in lower-middle-income Asian countries: Cambodia, Myanmar, Laos, Vietnam, Mongolia, and Bhutan as of June 2019 (before COVID-19), from the interviews of leading doctors in every country: (duplicated English publication from "the special Japanese edition of educational lectures in the 64th annual meeting of the Japanese Society for Dialysis Therapy").

Toru Hyodo, Akihiro C Yamashita, Nobuhito Hirawa, Yoshitaka Isaka, Hidetomo Nakamoto, Takashi Shigematsu

Renal replacement therapy　Vol. 8　No. 1　p. 54-54　2022　Research paper (scientific journal)

肥満関連尿細管症

山本 毅士, 高畠 義嗣, 猪阪 善隆

腎臓内科　Vol. 15　No. 1　p. 108-116　2022/01　Research paper (scientific journal)

Measurement of glomerular filtration rate using endogenous d-serine clearance in living kidney transplant donors and recipients.

Masataka Kawamura, Atsushi Hesaka, Ayumu Taniguchi, Shigeaki Nakazawa, Toyofumi Abe, Makoto Hirata, Ryuichi Sakate, Masaru Horio, Shiro Takahara, Norio Nonomura, Yoshitaka Isaka, Ryoichi Imamura, Tomonori Kimura

EClinicalMedicine　Vol. 43　p. 101223-101223　2022/01　Research paper (scientific journal)

Low-grade proteinuria and atherosclerotic cardiovascular disease: A transition study of patients with diabetic kidney disease.

Satoshi Yamaguchi, Takayuki Hamano, Tatsufumi Oka, Yohei Doi, Sachio Kajimoto, Yusuke Sakaguchi, Akira Suzuki, Yoshitaka Isaka

PloS one　Vol. 17　No. 2　2022　Research paper (scientific journal)

Reduction of Cell Surface T-Cell Receptor by Non-Mitogenic CD3 Antibody to Mitigate Murine Lupus.

Masashi Morita, Masayuki Mizui, Satoshi Masuyama, George C Tsokos, Yoshitaka Isaka

Frontiers in immunology　Vol. 13　p. 855812-855812　2022　Research paper (scientific journal)

Exercise-induced hypercalcemia and vasopressin-mediated bone resorption

M. Senda, T. Hamano, N. Fujii, T. Ito, Y. Sakaguchi, I. Matsui, Y. Isaka, T. Moriyama

Osteoporosis International　Vol. 32　No. 12　p. 2533-2541　2021/12　Research paper (scientific journal)

Single cell RNA sequencing uncovers cellular developmental sequences and novel potential intercellular communications in embryonic kidney

Isao Matsui, Ayumi Matsumoto, Kazunori Inoue, Yusuke Katsuma, Seiichi Yasuda, Karin Shimada, Yusuke Sakaguchi, Masayuki Mizui, Jun-ya Kaimori, Yoshitsugu Takabatake, Yoshitaka Isaka

Scientific Reports　Vol. 11　No. 1　p. 73-73　2021/12　Research paper (scientific journal)

Recurrent membranous nephropathy with a possible alteration in the etiology: a case report

Ayumi Matsumoto, Isao Matsui, Keiji Mano, Hitoshi Mizuno, Yusuke Katsuma, Seiichi Yasuda, Karin Shimada, Kazunori Inoue, Takashi Oki, Tadashi Hanai, Keiko Kojima, Tetsuya Kaneko, Yoshitaka Isaka

BMC Nephrology　Vol. 22　No. 1　p. 253-253　2021/12　Research paper (scientific journal)

Cholecalciferol supplementation attenuates bone loss in incident kidney transplant recipients: A prespecified secondary endpoint analysis of a randomized controlled trial

Makoto Tsujita, Yohei Doi, Yoshitsugu Obi, Takayuki Hamano, Toshihide Tomosugi, Kenta Futamura, Manabu Okada, Takahisa Hiramitsu, Norihiko Goto, Yoshitaka Isaka, Asami Takeda, Shunji Narumi, Yoshihiko Watarai

Journal of Bone and Mineral Research　2021/11/08　Research paper (scientific journal)

腹膜透析を導入した精神発達遅滞合併慢性腎不全症例の一例

中山 尋文, 北岡 太一, 武鑓 真司, 中野 由佳子, 大幡 泰久, 藤原 誠, 窪田 拓生, 大薗 恵一, 北村 温美, 猪阪 善隆

日本小児腎臓病学会雑誌　Vol. 34　No. 2　p. 203-203　2021/11　Research paper (scientific journal)

腹膜透析を導入した精神発達遅滞合併慢性腎不全症例の一例

中山 尋文, 北岡 太一, 武鑓 真司, 中野 由佳子, 大幡 泰久, 藤原 誠, 窪田 拓生, 大薗 恵一, 北村 温美, 猪阪 善隆

日本小児腎臓病学会雑誌　Vol. 34　No. 2　p. 203-203　2021/11

Vegetable Preference and Prediction of Proteinuria: A Retrospective Cohort Study

Shingo Ozaki, Ryohei Yamamoto, Maki Shinzawa, Ryohei Tomi, Ryuichi Yoshimura, Kaori Nakanishi, Makoto Nishida, Izumi Nagatomo, Takashi Kudo, Keiko Yamauchi-Takihara, Yoshitaka Isaka, Toshiki Moriyama

Annals of Nutrition and Metabolism　p. 1-7　2021/10/26　Research paper (scientific journal)

DFPPによるフィブリノゲン低下を防ぐための至適血漿処理量の設定について

太田 雄土, 峰松 佑輔, 南 茂, 難波 倫子, 猪阪 善隆, 高階 雅紀

日本アフェレシス学会雑誌　Vol. 40　No. Suppl.　p. 116-116　2021/10

Renoprotection by long‐term low‐dose tolvaptan in patients with heart failure and hyponatremia

Tatsufumi Oka, Takayuki Hamano, Tomohito Ohtani, Yohei Doi, Karin Shimada, Ayumi Matsumoto, Satoshi Yamaguchi, Nobuhiro Hashimoto, Masamitsu Senda, Yusuke Sakaguchi, Isao Matsui, Kei Nakamoto, Fusako Sera, Shungo Hikoso, Yasushi Sakata, Yoshitaka Isaka

ESC Heart Failure　Vol. 8　No. 6　p. 4904-4914　2021/09/23　Research paper (scientific journal)

Variability in estimated glomerular filtration rate and patients' outcomes in a real‐world heart failure population

Tatsufumi Oka, Takayuki Hamano, Tomohito Ohtani, Akihiro Tanaka, Yohei Doi, Satoshi Yamaguchi, Masamitsu Senda, Yusuke Sakaguchi, Isao Matsui, Kei Nakamoto, Fusako Sera, Shungo Hikoso, Masami Nishino, Yasushi Sakata, Yoshitaka Isaka

ESC Heart Failure　Vol. 8　No. 6　p. 4976-4987　2021/09/23　Research paper (scientific journal)

Demographic, clinical characteristics and treatment outcomes of immune-complex membranoproliferative glomerulonephritis and C3 glomerulonephritis in Japan: A retrospective analysis of data from the Japan Renal Biopsy Registry

Naoki Nakagawa, Masashi Mizuno, Sawako Kato, Shoichi Maruyama, Hiroshi Sato, Izaya Nakaya, Hitoshi Sugiyama, Shouichi Fujimoto, Kenichiro Miura, Chieko Matsumura, Yoshimitsu Gotoh, Hitoshi Suzuki, Aki Kuroki, Atsunori Yoshino, Shinya Nakatani, Keiju Hiromura, Ryohei Yamamoto, Hitoshi Yokoyama, Ichiei Narita, Yoshitaka Isaka

PLOS ONE　Vol. 16　No. 9　p. e0257397-e0257397　2021/09/14　Research paper (scientific journal)

Identification of diabetic nephropathy in patients undergoing kidney biopsy through blood and urinary profiles of D-serine

Yukimasa Iwata, Hiroki Okushima, Atsushi Hesaka, Masataka Kawamura, Ryoichi Imamura, Shiro Takahara, Masaru Horio, Youko Tanaka, Tatsuhiko Ikeda, Maiko Nakane, Masashi Mita, Terumasa Hayashi, Yoshitaka Isaka, Tomonori Kimura

Kidney360　p. 10.34067/KID.0004282021-10.34067/KID.0004282021　2021/09/09　Research paper (scientific journal)

Focal segmental glomerulosclerosis histologic variants and renal outcomes based on nephrotic syndrome, immunosuppression, and proteinuria remission

Takehiko Kawaguchi, Toshiyuki Imasawa, Moritoshi Kadomura, Hiroshi Kitamura, Shoichi Maruyama, Takaya Ozeki, Ritsuko Katafuchi, Kazumasa Oka, Yoshitaka Isaka, Hitoshi Yokoyama, Hitoshi Sugiyama, Hiroshi Sato

Nephrology Dialysis Transplantation　Vol. 37　No. 9　p. 1679-1690　2021/09/09　Research paper (scientific journal)

家系内に多くのCKD患者を認めた、成人発症原発性高シュウ酸尿症1型の症例

貝森 淳哉, 中村 好男, 坂口 悠介, 岡 樹史, 土井 洋平, 梶本 幸男, 朝比奈 悠太, 服部 洸輝, 永田 美保, 石原 康貴, 宮下 洋平, 朝野 仁裕, 猪阪 善隆

日本腎臓学会誌　Vol. 63　No. 6-W　p. 831-831　2021/09

移植後10年以上経過した腎移植患者のグラフト生検の臨床的意義

難波 倫子, 濱野 高行, 京 昌弘, 谷口 歩, 田中 亮, 山中 和明, 阿部 豊文, 客野 宮治, 今村 亮一, 野々村 祝夫, 猪阪 善隆

移植　Vol. 56　No. 総会臨時　p. O6-2　2021/09

The effect of cholecalciferol supplementation on allograft function in incident kidney transplant recipients: A randomized controlled study

Yohei Doi, Makoto Tsujita, Takayuki Hamano, Yoshitsugu Obi, Tomoko Namba‐Hamano, Toshihide Tomosugi, Kenta Futamura, Manabu Okada, Takahisa Hiramitsu, Norihiko Goto, Akira Nishiyama, Asami Takeda, Shunji Narumi, Yoshihiko Watarai, Yoshitaka Isaka

American Journal of Transplantation　Vol. 21　No. 9　p. 3043-3054　2021/09　Research paper (scientific journal)

D-Serine mediates cellular proliferation for kidney remodeling

Atsushi Hesaka, Yusuke Tsukamoto, Shigeyuki Nada, Masataka Kawamura, Naotsugu Ichimaru, Shinsuke Sakai, Maiko Nakane, Masashi Mita, Daisuke Okuzaki, Masato Okada, Yoshitaka Isaka, Tomonori Kimura

Kidney360　p. 10.34067/KID.0000832021-10.34067/KID.0000832021　2021/08/16　Research paper (scientific journal)

糖尿病および合併症治療の展望〜糖尿病患者の健康長寿への架け橋〜 オートファジーと腎

猪阪 善隆

糖尿病合併症　Vol. 35　No. 2　p. 175-178　2021/08　Research paper (scientific journal)

Intra-body dynamics of d-serine reflects the origin of kidney diseases

Hiroki Okushima, Yukimasa Iwata, Atsushi Hesaka, Eri Sugimori, Tatsuhiko Ikeda, Maiko Nakane, Masashi Mita, Terumasa Hayashi, Yoshitaka Isaka, Tomonori Kimura

Clinical and Experimental Nephrology　Vol. 25　No. 8　p. 893-901　2021/08　Research paper (scientific journal)

Mean corpuscular hemoglobin concentration: an anemia parameter predicting cardiovascular disease in incident dialysis patients

Satoshi Yamaguchi, Takayuki Hamano, Tatsufumi Oka, Yohei Doi, Sachio Kajimoto, Karin Shimada, Ayumi Matsumoto, Yusuke Sakaguchi, Isao Matsui, Akira Suzuki, Yoshitaka Isaka

Journal of Nephrology　Vol. 35　No. 2　p. 535-544　2021/07/02　Research paper (scientific journal)

家族性尿細管間質腎炎 自験例を中心として

貝森 淳哉, 猪阪 善隆

BIO Clinica　Vol. 36　No. 8　p. 803-807　2021/07　Research paper (scientific journal)

【腎臓医が診る指定難病】指定難病各論 糸球体疾患 一次性ネフローゼ症候群

猪阪 善隆

腎と透析　Vol. 91　No. 1　p. 51-54　2021/07　Research paper (scientific journal)

【CKD・薬剤性腎障害・特殊な患者背景への実践的アプローチ!腎臓病薬物療法コンサルテーション】(第5章)症例に学ぶ!腎機能評価と薬剤投与時の注意点 高齢者

猪阪 善隆

薬事　Vol. 63　No. 10　p. 2146-2151　2021/07　Research paper (scientific journal)

今後の腎移植におけるAIの展望

松井 功, 松本 あゆみ, 奥嶋 拓樹, 勝間 勇介, 安田 聖一, 井上 和則, 猪阪 善隆

日本臨床腎移植学会雑誌　Vol. 9　No. 1　p. 15-22　2021/07　Research paper (scientific journal)

Association of Time-Updated Anion Gap With Risk of Kidney Failure in Advanced CKD: A Cohort Study

Yuta Asahina, Yusuke Sakaguchi, Sachio Kajimoto, Kohki Hattori, Yohei Doi, Tatsufumi Oka, Jun-Ya Kaimori, Yoshitaka Isaka

American Journal of Kidney Diseases　Vol. 79　No. 3　p. 374-382　2021/07　Research paper (scientific journal)

Quantitative Analyses of Foot Processes, Mitochondria, and Basement Membranes by Structured Illumination

Ayumi Matsumoto, Isao Matsui, Yusuke Katsuma, Seiichi Yasuda, Karin Shimada, Tomoko Namba-Hamano, Yusuke Sakaguchi, Jun-ya Kaimori, Yoshitsugu Takabatake, Kazunori Inoue, Yoshitaka Isaka

Kidney International Reports　Vol. 6　No. 7　p. 1923-1938　2021/07　Research paper (scientific journal)

ループス腎炎易発性マウスの治療における細胞分裂非促進性抗CD3抗体療法の有効性と安全性(Efficacy and safety of non-mitogenic anti-CD3 in the treatment of lupus-prone mice)

Morita Masashi, Mizui Masayuki, Masuyama Satoshi, Isaka Yoshitaka

日本腎臓学会誌　Vol. 63　No. 4　p. 455-455　2021/06　Research paper (scientific journal)

D-セリンの体内動態は腎臓病の原疾患を反映する

奥嶋 拓樹, 岩田 幸真, 岡本 和大, 柴田 祥吾, 上床 隆太, 川村 知央, 橋本 展洋, 上田 仁康, 勝二 達也, 林 晃正, 池田 達彦, 三田 真史, 猪阪 善隆, 部坂 篤, 木村 友則

日本腎臓学会誌　Vol. 63　No. 4　p. 464-464　2021/06　Research paper (scientific journal)

TFEBはリソソーマルエクソサイトーシスを介したリン脂質蓄積抑制により腎保護的に働く

中村 隼, 山本 毅士, 高畠 義嗣, 難波 倫子, 南 聡, 高橋 篤史, 松田 潤, 酒井 晋介, 余西 洋明, 前田 志穂美, 新村 文男, 松阪 泰二, 猪阪 善隆

日本腎臓学会誌　Vol. 63　No. 4　p. 439-439　2021/06　Research paper (scientific journal)

マグネシウムはRubicon抑制を介したオートファジー活性化により高リン腎毒性を軽減する

山本 毅士, 高畠 義嗣, 藤村 龍太, 難波 倫子, 余西 洋明, 中村 隼, 高橋 篤史, 松田 潤, 南 聡, 酒井 晋介, 前田 志穂美, 坂口 悠介, 新村 文男, 松阪 泰二, 猪阪 善隆

日本腎臓学会誌　Vol. 63　No. 4　p. 440-440　2021/06　Research paper (scientific journal)

Atg5はマイトファジーおよびミトコンドリア再生を介してAKIからCKDへの進展を抑制する

南 聡, 山本 毅士, 高畠 義嗣, 高橋 篤史, 難波 倫子, 松田 潤, 酒井 晋介, 余西 洋明, 中村 隼, 前田 志穂美, 新村 文男, 松阪 泰二, 柳田 素子, 猪阪 善隆

日本腎臓学会誌　Vol. 63　No. 4　p. 458-458　2021/06　Research paper (scientific journal)

近位尿細管オートファジー不全は、腎糖新生亢進を介して耐糖能異常を悪化させる

酒井 晋介, 山本 毅士, 高畠 義嗣, 高橋 篤史, 難波 倫子, 松田 潤, 南 聡, 余西 洋明, 中村 隼, 前田 志穂美, 新村 文男, 松阪 泰二, 猪阪 善隆

日本腎臓学会誌　Vol. 63　No. 4　p. 476-476　2021/06　Research paper (scientific journal)

加齢関連腎疾患から保護するため、オートファジー不全は線維芽細胞増殖因子21を強く誘発する(Fibroblast Growth Factor 21 is Robustly Induced by Autophagy Deficiency to Protect Against Age-related Kidney Disease)

山本 毅士, 南 聡, 酒井 晋介, 高畠 義嗣, 猪阪 善隆

日本抗加齢医学会総会プログラム・抄録集　Vol. 21回　p. 195-195　2021/06　Research paper (scientific journal)

腎移植後早期からの天然型ビタミンD3補充と骨密度変化 二重盲検プラセボ対照ランダム化比較試験

土井 洋平, 濱野 高行, 辻田 誠, 猪阪 善隆

日本腎臓学会誌　Vol. 63　No. 4　p. 426-426　2021/06　Research paper (scientific journal)

移植後10年以上経過した腎移植患者のグラフト生検の臨床的意義

難波 倫子, 濱野 高行, 谷口 歩, 川村 正隆, 加藤 大悟, 阿部 豊文, 今村 亮一, 高畠 義嗣, 野々村 祝夫, 猪阪 善隆

日本腎臓学会誌　Vol. 63　No. 4　p. 450-450　2021/06　Research paper (scientific journal)

【腎疾患レジストリーの展望】高齢者ネフローゼ症候群コホート研究・膜性腎症における年齢層別予後調査

横山 仁, 杉山 斉, 佐藤 博, 山本 陵平, 猪阪 善隆

腎臓内科　Vol. 13　No. 6　p. 729-736　2021/06　Research paper (scientific journal)

大阪府内科医会会員 慢性腎臓病(CKD)治療の実態調査の変化

猪阪 善隆, 外山 学, 泉岡 利於, 村田 秀穗, 小林 寿治, 竺原 俊光, 福田 正博

大阪府内科医会会誌　Vol. 30　No. 1　p. 70-77　2021/06　Research paper (scientific journal)

Occupational sedentary behavior and prediction of proteinuria in young to middle-aged adults: a retrospective cohort study

Yoshiyuki Fujii, Ryohei Yamamoto, Maki Shinzawa, Yoshiki Kimura, Katsunori Aoki, Ryohei Tomi, Shingo Ozaki, Ryuichi Yoshimura, Manabu Taneike, Kaori Nakanishi, Makoto Nishida, Keiko Yamauchi-Takihara, Takashi Kudo, Yoshitaka Isaka, Toshiki Moriyama

Journal of Nephrology　Vol. 34　No. 3　p. 719-728　2021/06　Research paper (scientific journal)

Clinical characteristics of COVID-19 infection in a dialysis center during a nosocomial outbreak

Rei Iio, Tetsuya Kaneko, Hitoshi Mizuno, Yoshitaka Isaka

Clinical and Experimental Nephrology　Vol. 25　No. 6　p. 652-659　2021/06　Research paper (scientific journal)

Cyclosporine A Treatment of Proteinuria in a New Case of MAFB-Associated Glomerulopathy without Extrarenal Involvement: A Case Report

Jun-Ya Kaimori, Tatsuhiko Mori, Tomoko Namba-Hamano, Takeshi Morimoto, Ayako Takuwa, Daisuke Motooka, Atsuko Okazaki, Kaori Kobayashi, Yuta Asahina, Sachio Kajimoto, Yohei Doi, Tatsufumi Oka, Yusuke Sakaguchi, Akihiro Nakaya, Yoshitaka Isaka

Nephron　Vol. 145　No. 4　p. 445-450　2021/05/11　Research paper (scientific journal)

【水・電解質を科学する】体液異常の病態と治療 浮腫の発症メカニズムと治療

猪阪 善隆

腎と透析　Vol. 90　No. 5　p. 812-815　2021/05　Research paper (scientific journal)

COVID-19流行環境下における慢性腎臓病診療および受療行動変化の実態調査

坪井 伸夫, 伊藤 孝史, 田村 功一, 猪阪 善隆, 岡田 浩一, 南学 正臣, 柏原 直樹, 横尾 隆

日本腎臓学会誌　Vol. 63　No. 3　p. 283-296　2021/05　Research paper (scientific journal)

【水・電解質を科学する】体液異常の病態と治療 浮腫の発症メカニズムと治療

猪阪 善隆

腎と透析　Vol. 90　No. 5　p. 812-815　2021/05

アディポネクチンのT-cadherinを介した血管周皮細胞への集積と腎保護作用

清水 有理, 藤島 裕也, 喜多 俊文, 南 聡, 坂上 貴章, 中村 勇斗, 堀谷 恵美, 沖田 朋憲, 川知 祐介, 福田 士郎, 難波 倫子, 高畠 義嗣, 猪阪 善隆, 西澤 均, 前田 法一, 下村 伊一郎

糖尿病　Vol. 64　No. Suppl.1　p. YIA-3)　2021/05

Electrocardiogram findings at the initiation of hemodialysis and types of subsequent cardiovascular events

Satoshi Yamaguchi, Takayuki Hamano, Tatsufumi Oka, Yohei Doi, Sachio Kajimoto, Seiichi Yasuda, Karin Shimada, Ayumi Matsumoto, Yusuke Sakaguchi, Kazunori Inoue, Isao Matsui, Akira Suzuki, Yoshitaka Isaka

Hypertension Research　Vol. 44　No. 5　p. 571-580　2021/05　Research paper (scientific journal)

Incidence and factors associated with prescribing renin‐angiotensin‐system inhibitors in adult idiopathic nephrotic syndrome: A nationwide cohort study

Hiroki Nishiwaki, Kakuya Niihata, Sayaka Shimizu, Yugo Shibagaki, Ryohei Yamamoto, Kosaku Nitta, Tatsuo Tsukamoto, Shunya Uchida, Asami Takeda, Hirokazu Okada, Ichiei Narita, Yoshitaka Isaka, Noriaki Kurita, Enyu Imai, Shoichi Maruyama, Toshinobu Sato, Hiroshi Sato, Takashi Wada, Hiroki Hayashi, Yasuhiro Akai, Megumu Fukunaga, Kazuhiko Tsuruya, Kosuke Masutani, Tsuneo Konta, Hitoshi Yokoyama, Tatsuya Shoji, Takeyuki Hiramatsu, Shunsuke Goto, Hitoshi Sugiyama, Hirofumi Tamai, Saori Nishio, Arimasa Shirasaki, Kojiro Nagai, Kunihiro Yamagata, Hajime Hasegawa, Hidemo Yasuda, Shizunori Ichida, Tomohiko Naruse, Kei Fukami, Tomoya Nishino, Hiroshi Sobajima, Satoshi Tanaka, Toshiyuki Akahori, Takafumi Ito, Yoshio Terada, Ritsuko Katafuchi, Shouichi Fujimoto, Eiji Ishimura, Junichiro James Kazama, Keiju Hiromura, Tetsushi Mimura, Satashi Suzuki, Yosuke Saka, Tadashi Sofue, Yusuke Suzuki, Kiyoki Kitagawa, Kunio Morozumi, Yoshiro Fujita, Makoto Mizutani, Takashi Shigematsu, Naoki Kashihara, Seiichi Matsuo

The Journal of Clinical Hypertension　Vol. 23　No. 5　p. 999-1007　2021/05　Research paper (scientific journal)

Correcting Anemia and Native Vitamin D Supplementation in Kidney Transplant Recipients (CANDLE‐KIT): a Multicenter, 2×2 Factorial, Open‐label, Randomized Clinical Trial

Yoshitsugu Obi, Naotsugu Ichimaru, Yusuke Sakaguchi, Kazuhiro Iwadoh, Daisuke Ishii, Ken Sakai, Daiki Iwami, Hiroshi Harada, Keiichi Sumida, Akinari Sekine, Kosuke Masutani, Naotake Akutsu, Takamitsu Inoue, Morikuni Nishihira, Tatsuo Yoneda, Shinichi Ito, Motoo Araki, Jun‐Ya Kaimori, Katsunori Yoshida, Shigeru Satoh, Yoshifumi Ubara, Yoshitaka Isaka, Kazunari Yoshida, Yoshiharu Tsubakihara, Shiro Takahara, Takayuki Hamano

Transplant International　Vol. 34　No. 7　p. 1212-1225　2021/04/22　Research paper (scientific journal)

Optimal Protein Intake in Pre-Dialysis Chronic Kidney Disease Patients with Sarcopenia: An Overview

Yoshitaka Isaka

Nutrients　Vol. 13　No. 4　p. 1205-1205　2021/04/06　Research paper (scientific journal)

【維持透析患者のヘルシーエイジングに向けて】早期発見、専門医への紹介ポイント、ケア 微熱が続く、寝汗をかく 主に結核について

猪阪 善隆

腎と透析　Vol. 90　No. 4　p. 593-595　2021/04　Research paper (scientific journal)

Maxacalcitol (22-Oxacalcitriol (OCT)) Retards Progression of Left Ventricular Hypertrophy with Renal Dysfunction Through Inhibition of Calcineurin-NFAT Activity

Kazunori Inoue, Isao Matsui, Takayuki Hamano, Keiji Okuda, Yasumasa Tsukamoto, Ayumi Matsumoto, Karin Shimada, Seiichi Yasuda, Yusuke Katsuma, Yoshitsugu Takabatake, Masaru Tanaka, Noriko Tanaka, Toshiaki Mano, Tetsuo Minamino, Yasushi Sakata, Yoshitaka Isaka

Cardiovascular Drugs and Therapy　Vol. 35　No. 2　p. 381-397　2021/04　Research paper (scientific journal)

【維持透析患者のヘルシーエイジングに向けて】早期発見、専門医への紹介ポイント、ケア 微熱が続く、寝汗をかく 主に結核について

猪阪 善隆

腎と透析　Vol. 90　No. 4　p. 593-595　2021/04　Research paper (scientific journal)

Dermatologist and Patient Perceptions of Treatment Success in Alopecia Areata and Evaluation of Clinical Outcome Assessments in Japan

Jake Macey, Helen Kitchen, Natalie V. J. Aldhouse, Russel T. Burge, Emily Edson-Heredia, Jill S. McCollam, Yoshitaka Isaka, Hitoe Torisu-Itakura

Dermatology and Therapy　Vol. 11　No. 2　p. 433-447　2021/04　Research paper (scientific journal)

THOC4 regulates energy homeostasis by stabilizing TFEB mRNA during prolonged starvation

Toshiharu Fujita, Sayaka Kubo, Tatsuya Shioda, Ayaka Tokumura, Satoshi Minami, Megumi Tsuchiya, Yoshitaka Isaka, Hidesato Ogawa, Maho Hamasaki, Li Yu, Tamotsu Yoshimori, Shuhei Nakamura

Journal of Cell Science　Vol. 134　No. 6　2021/03/15　Research paper (scientific journal)

Optimal Phosphate Control Related to Coronary Artery Calcification in Dialysis Patients

Yoshitaka Isaka, Takayuki Hamano, Hideki Fujii, Yoshihiro Tsujimoto, Fumihiko Koiwa, Yusuke Sakaguchi, Ryoichi Tanaka, Noriyuki Tomiyama, Fuminari Tatsugami, Satoshi Teramukai

Journal of the American Society of Nephrology　Vol. 32　No. 3　p. 723-735　2021/03　Research paper (scientific journal)

【来たるべくデジタルヘルスケア革命-乗り遅れるな腎臓病学!-】AIの可能性

猪阪 善隆

腎と透析　Vol. 90　No. 2　p. 173-177　2021/02　Research paper (scientific journal)

【来たるべくデジタルヘルスケア革命-乗り遅れるな腎臓病学!-】腎臓領域の現在の取り組み 腎生検病理と人工知能

松井 功, 松本 あゆみ, 猪阪 善隆

腎と透析　Vol. 90　No. 2　p. 260-266　2021/02　Research paper (scientific journal)

Increased vascular permeability and severe renal tubular damage after ischemia-reperfusion injury in mice lacking adiponectin or T-cadherin

Yuri Tsugawa-Shimizu, Yuya Fujishima, Shunbun Kita, Satoshi Minami, Taka-aki Sakaue, Yuto Nakamura, Tomonori Okita, Yusuke Kawachi, Shiro Fukada, Tomoko Namba-Hamano, Yoshitsugu Takabatake, Yoshitaka Isaka, Hitoshi Nishizawa, Barbara Ranscht, Norikazu Maeda, Iichiro Shimomura

American Journal of Physiology-Endocrinology and Metabolism　Vol. 320　No. 2　p. E179-E190　2021/02/01　Research paper (scientific journal)

Efficacy of aerobic exercise on the cardiometabolic and renal outcomes in patients with chronic kidney disease: a systematic review of randomized controlled trials

Ryohei Yamamoto, Takafumi Ito, Yasuyuki Nagasawa, Kosuke Matsui, Masahiro Egawa, Masayoshi Nanami, Yoshitaka Isaka, Hirokazu Okada

Journal of Nephrology　Vol. 34　No. 1　p. 155-164　2021/02　Research paper (scientific journal)

D-セリンは腎臓のリモデリングを促進する

部坂篤, 塚本悠介, 名田茂之, 川村正隆, 市丸直嗣, 三田真史, 奥崎大介, 岡田正人, 猪阪善隆, 木村友則

日本腎臓学会誌(Web)　Vol. 63　No. 4　2021　Research paper (scientific journal)

Modulation of the Association of Hypobicarbonatemia and Incident Kidney Failure With Replacement Therapy by Venous pH: A Cohort Study

Sachio Kajimoto, Yusuke Sakaguchi, Yuta Asahina, Jun-Ya Kaimori, Yoshitaka Isaka

American Journal of Kidney Diseases　Vol. 77　No. 1　p. 35-43　2021/01　Research paper (scientific journal)

【腎性貧血治療のこれまでと,その新しい展開】これまでの腎性貧血治療 腎性貧血治療の課題 b.透析期での課題

朝比奈 悠太, 土井 洋平, 坂口 悠介, 貝森 淳哉, 猪阪 善隆

臨床透析　Vol. 37　No. 1　p. 47-52　2021/01　Research paper (scientific journal)

【腎疾患領域における難病対策】ネフローゼ症候群における対策

猪阪 善隆

腎臓内科　Vol. 13　No. 1　p. 62-68　2021/01　Research paper (scientific journal)

Urinary mulberry bodies as a potential biomarker for early diagnosis and efficacy assessment of enzyme replacement therapy in Fabry nephropathy

Hiroaki Yonishi, Tomoko Namba-Hamano, Takayuki Hamano, Masaki Hotta, Jun Nakamura, Shinsuke Sakai, Satoshi Minami, Takeshi Yamamoto, Atsushi Takahashi, Wataru Kobayashi, Ikuhiro Maeda, Yoh Hidaka, Yoshitsugu Takabatake, Norio Sakai, Yoshitaka Isaka

Nephrology Dialysis Transplantation　Vol. 37　No. 1　p. 53-62　2020/12/24　Research paper (scientific journal)

Effect of cholecalciferol on serum hepcidin and parameters of anaemia and CKD-MBD among haemodialysis patients: a randomized clinical trial

Yoshitsugu Obi, Satoshi Yamaguchi, Takayuki Hamano, Yusuke Sakaguchi, Akihiro Shimomura, Tomoko Namba-Hamano, Satoshi Mikami, Osamu Nishi, Motoko Tanaka, Akihito Kamoto, Yasue Obi, Naohisa Tomosugi, Yoshiharu Tsubakihara, Yoshitaka Isaka

Scientific Reports　Vol. 10　No. 1　p. 15500-15500　2020/12　Research paper (scientific journal)

Dietary casein, egg albumin, and branched-chain amino acids attenuate phosphate-induced renal tubulointerstitial injury in rats

Karin Shimada, Isao Matsui, Kazunori Inoue, Ayumi Matsumoto, Seiichi Yasuda, Yusuke Katsuma, Yusuke Sakaguchi, Minoru Tanaka, Ken Sugimoto, Jun-ya Kaimori, Yoshitsugu Takabatake, Yoshitaka Isaka

Scientific Reports　Vol. 10　No. 1　p. 19038-19038　2020/12　Research paper (scientific journal)

J-CKD-DB: a nationwide multicentre electronic health record-based chronic kidney disease database in Japan

Naoki Nakagawa, Tadashi Sofue, Eiichiro Kanda, Hajime Nagasu, Kunihiro Matsushita, Masaomi Nangaku, Shoichi Maruyama, Takashi Wada, Yoshio Terada, Kunihiro Yamagata, Ichiei Narita, Motoko Yanagita, Hitoshi Sugiyama, Takashi Shigematsu, Takafumi Ito, Kouichi Tamura, Yoshitaka Isaka, Hirokazu Okada, Kazuhiko Tsuruya, Hitoshi Yokoyama, Naoki Nakashima, Hiromi Kataoka, Kazuhiko Ohe, Mihoko Okada, Naoki Kashihara

Scientific Reports　Vol. 10　No. 1　p. 7351-7351　2020/12　Research paper (scientific journal)

Serum phosphate levels modify the impact of parathyroid hormone levels on renal outcomes in kidney transplant recipients

Yohei Doi, Takayuki Hamano, Naotsugu Ichimaru, Kodo Tomida, Yoshitsugu Obi, Naohiko Fujii, Satoshi Yamaguchi, Tatsufumi Oka, Yusuke Sakaguchi, Isao Matsui, Jun-ya Kaimori, Toyofumi Abe, Ryoichi Imamura, Shiro Takahara, Yoshiharu Tsubakihara, Norio Nonomura, Yoshitaka Isaka

Scientific Reports　Vol. 10　No. 1　p. 13766-13766　2020/12　Research paper (scientific journal)

Frequency of Breakfast, Lunch, and Dinner and Incidence of Proteinuria: A Retrospective Cohort Study

Ryohei Tomi, Ryohei Yamamoto, Maki Shinzawa, Yoshiki Kimura, Yoshiyuki Fujii, Katsunori Aoki, Shingo Ozaki, Ryuichi Yoshimura, Manabu Taneike, Kaori Nakanishi, Makoto Nishida, Keiko Yamauchi-Takihara, Takashi Kudo, Yoshitaka Isaka, Toshiki Moriyama

Nutrients　Vol. 12　No. 11　p. 3549-3549　2020/11/19　Research paper (scientific journal)

An Optimized Crovalimab Dose and Regimen Reduced the Formation of Drug-Target-Drug Complexes in Patients with Paroxysmal Nocturnal Hemoglobinuria from the Phase I/II COMPOSER Trial

Jun-Ichi Nishimura, Antoine Soubret, Simon Buatois, Jean-Eric Charoin, Sasha Sreckovic, Christoph Bucher, Jules Hernandez-Sanchez, Gregor Jordan, Julia Ramos, Noriko Arase, Masaki Hotta, Yoshitaka Isaka, Yoshikazu Ito, Yuzuru Kanakura, Jin Seok Kim, Taroh Kinoshita, Eiichi Morii, Jens Panse, Regis Peffault De latour, Alexander Roth, Hubert Schrezenmeier, Simona Sica, Hiroyuki Takamori, Yasutaka Ueda, Sung-Soo Yoon, Ido Paz-Priel, Alexandre Sostelly

BLOOD　Vol. 136　2020/11

【腎臓内科医が知っておくべき遺伝性腎疾患】MUC1遺伝子異常による常染色体優性遺伝性尿細管間質性腎疾患(ADTKD-MUC1)

貝森 淳哉, 坂口 悠介, 猪阪 善隆

腎臓内科　Vol. 12　No. 5　p. 525-529　2020/11　Research paper (scientific journal)

【腎臓内科医が知っておくべき遺伝性腎疾患】Dent病

松井 功, 井上 和則, 松本 あゆみ, 猪阪 善隆

腎臓内科　Vol. 12　No. 5　p. 530-537　2020/11　Research paper (scientific journal)

糖尿病および合併症治療の展望〜糖尿病患者の健康長寿への架け橋〜 オートファジーと腎

猪阪 善隆

糖尿病合併症　Vol. 34　No. Suppl.1　p. 106-106　2020/11　Research paper (scientific journal)

【水電解質】遠位尿細管でのMg輸送機構とその臨床的意義

坂口 悠介, 貝森 淳哉, 猪阪 善隆

日本腎臓学会誌　Vol. 62　No. 8　p. 790-797　2020/11　Research paper (scientific journal)

Efficacy of corticosteroid therapy for IgA nephropathy patients stratified by kidney function and proteinuria.

Yasuyuki Nagasawa, Ryohei Yamamoto, Maki Shinzawa, Tatsuya Shoji, Yukiko Hasuike, Katsuyuki Nagatoya, Atsushi Yamauchi, Terumasa Hayashi, Takayuki Kuragano, Toshiki Moriyama, Yoshitaka Isaka

Clinical and experimental nephrology　Vol. 24　No. 10　p. 927-934　2020/10　Research paper (scientific journal)

LC3 lipidation is essential for TFEB activation during the lysosomal damage response to kidney injury

Shuhei Nakamura, Saki Shigeyama, Satoshi Minami, Takayuki Shima, Shiori Akayama, Tomoki Matsuda, Alessandra Esposito, Gennaro Napolitano, Akiko Kuma, Tomoko Namba-Hamano, Jun Nakamura, Kenichi Yamamoto, Miwa Sasai, Ayaka Tokumura, Mika Miyamoto, Yukako Oe, Toshiharu Fujita, Seigo Terawaki, Atsushi Takahashi, Maho Hamasaki, Masahiro Yamamoto, Yukinori Okada, Masaaki Komatsu, Takeharu Nagai, Yoshitsugu Takabatake, Haoxing Xu, Yoshitaka Isaka, Andrea Ballabio, Tamotsu Yoshimori

Nature Cell Biology　Vol. 22　No. 10　p. 1252-1263　2020/10　Research paper (scientific journal)

高齢CKD 患者の診察

Geriatric Medicine　Vol. 58　No. 10　p. 903-905　2020/10　Research paper (scientific journal)

Utility of d-serine monitoring in kidney disease

Tomonori Kimura, Atsushi Hesaka, Yoshitaka Isaka

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics　Vol. 1868　No. 9　p. 140449-140449　2020/09　Research paper (scientific journal)

腎代替療法選択と導入後管理

猪阪 善隆

日本内科学会雑誌　Vol. 109　No. 9　p. 1919-1924　2020/09　Research paper (scientific journal)

Conservative Kidney Managementを含めた腎代替療法選択 最適な腎代替療法選択のために 腎代替療法選択ガイド2020

猪阪 善隆

Therapeutic Research　Vol. 41　No. 9　p. 719-723　2020/09　Research paper (scientific journal)

スクロオキシ水酸化鉄顆粒剤のアドヒアランス、有効性、安全性に関する後向き研究

土井 洋平, 下村 明弘, 猪阪 善隆

日本透析医学会雑誌　Vol. 53　No. 9　p. 477-485　2020/09　Research paper (scientific journal)

Duration of predialysis nephrological care and mortality after dialysis initiation.

Yukimasa Iwata, Hiroki Okushima, Taisuke Takatsuka, Daisuke Yoshimura, Tomohiro Kawamura, Rei Iio, Yoshiyasu Ueda, Tatsuya Shoji, Terumasa Hayashi, Yoshitaka Isaka

Clinical and experimental nephrology　Vol. 24　No. 8　p. 705-714　2020/08　Research paper (scientific journal)

透析患者に対する静脈栄養

猪阪 善隆

臨床栄養　Vol. 137　No. 2　p. 138-139　2020/08　Research paper (scientific journal)

Prevalence of anemia in patients with chronic kidney disease in Japan: A nationwide, cross-sectional cohort study using data from the Japan Chronic Kidney Disease Database (J-CKD-DB)

Tadashi Sofue, Naoki Nakagawa, Eiichiro Kanda, Hajime Nagasu, Kunihiro Matsushita, Masaomi Nangaku, Shoichi Maruyama, Takashi Wada, Yoshio Terada, Kunihiro Yamagata, Ichiei Narita, Motoko Yanagita, Hitoshi Sugiyama, Takashi Shigematsu, Takafumi Ito, Kouichi Tamura, Yoshitaka Isaka, Hirokazu Okada, Kazuhiko Tsuruya, Hitoshi Yokoyama, Naoki Nakashima, Hiromi Kataoka, Kazuhiko Ohe, Mihoko Okada, Naoki Kashihara

PLOS ONE　Vol. 15　No. 7　p. e0236132-e0236132　2020/07/20　Research paper (scientific journal)

Frequency of alcohol drinking modifies the association between salt intake and albuminuria: a 1-year observational study.

Ryuichi Yoshimura, Ryohei Yamamoto, Maki Shinzawa, Ryohei Tomi, Shingo Ozaki, Yoshiyuki Fujii, Takafumi Ito, Kazuaki Tanabe, Yasuaki Moriguchi, Yoshitaka Isaka, Toshiki Moriyama

Hypertension research : official journal of the Japanese Society of Hypertension　Vol. 43　No. 11　p. 1249-1256　2020/07/10　Research paper (scientific journal)

当科におけるLowe症候群症例の腎機能と成人診療科への移行

中山 尋文, 藤原 誠, 窪田 拓生, 山田 知絵子, 宮田 京, 武鑓 真司, 中野 由佳子, 山本 賢一, 大幡 泰久, 北岡 太一, 大薗 恵一, 下村 明弘, 南 聡, 猪阪 善隆

日本小児腎不全学会雑誌　Vol. 40　p. 129-134　2020/07　Research paper (scientific journal)

慢性維持透析患者に対する静脈栄養ならびに経腸栄養に関する提言

猪阪 善隆, 菅野 義彦, 花房 規男, 細島 康宏, 長井 美穂, 吉田 朋子, 湯浅 愛, 日本透析医学会透析患者に対する静脈栄養剤投与ならびに経腸栄養に関する提言検討委員会

日本透析医学会雑誌　Vol. 53　No. 7　p. 373-391　2020/07　Research paper (scientific journal)

Better remission rates in elderly Japanese patients with primary membranous nephropathy in nationwide real-world practice: The Japan Nephrotic Syndrome Cohort Study (JNSCS).

Hitoshi Yokoyama, Ryohei Yamamoto, Enyu Imai, Shoichi Maruyama, Hitoshi Sugiyama, Kosaku Nitta, Tatsuo Tsukamoto, Shunya Uchida, Asami Takeda, Toshinobu Sato, Takashi Wada, Hiroki Hayashi, Yasuhiro Akai, Megumu Fukunaga, Kazuhiko Tsuruya, Kosuke Masutani, Tsuneo Konta, Tatsuya Shoji, Takeyuki Hiramatsu, Shunsuke Goto, Hirofumi Tamai, Saori Nishio, Arimasa Shirasaki, Kojiro Nagai, Kunihiro Yamagata, Hajime Hasegawa, Hidemo Yasuda, Shizunori Ichida, Tomohiko Naruse, Kei Fukami, Tomoya Nishino, Hiroshi Sobajima, Satoshi Tanaka, Toshiyuki Akahori, Takafumi Ito, Yoshio Terada, Ritsuko Katafuchi, Shouichi Fujimoto, Hirokazu Okada, Eiji Ishimura, Junichiro James Kazama, Keiju Hiromura, Tetsushi Mimura, Satashi Suzuki, Yosuke Saka, Tadashi Sofue, Yusuke Suzuki, Yugo Shibagaki, Kiyoki Kitagawa, Kunio Morozumi, Yoshiro Fujita, Makoto Mizutani, Takashi Shigematsu, Kengo Furuichi, Keiji Fujimoto, Naoki Kashihara, Hiroshi Sato, Seiichi Matsuo, Ichiei Narita, Yoshitaka Isaka

Clinical and experimental nephrology　Vol. 24　No. 10　p. 893-909　2020/06/19　Research paper (scientific journal)

Eicosapentaenoic acid attenuates renal lipotoxicity by restoring autophagic flux.

Takeshi Yamamoto, Yoshitsugu Takabatake, Satoshi Minami, Shinsuke Sakai, Ryuta Fujimura, Atsushi Takahashi, Tomoko Namba-Hamano, Jun Matsuda, Tomonori Kimura, Isao Matsui, Jun-Ya Kaimori, Hiroaki Takeda, Masatomo Takahashi, Yoshihiro Izumi, Takeshi Bamba, Taiji Matsusaka, Fumio Niimura, Motoko Yanagita, Yoshitaka Isaka

Autophagy　Vol. 17　No. 7　p. 1700-1713　2020/06/16　Research paper (scientific journal)

家族性尿細管間質腎炎 自験例を中心として

貝森 淳哉, 猪阪 善隆

BIO Clinica　Vol. 35　No. 6　p. 554-558　2020/06　Research paper (scientific journal)

【症例で学ぶ!腎泌尿器診療ガイドラインの使い方】(第2章)代表的腎疾患 急性腎障害(AKI) 造影剤によるAKI

猪阪 善隆

腎と透析　Vol. 88　No. 増刊　p. 42-46　2020/06　Research paper (scientific journal)

Incidence of remission and relapse of proteinuria, end-stage kidney disease, mortality, and major outcomes in primary nephrotic syndrome: the Japan Nephrotic Syndrome Cohort Study (JNSCS).

Ryohei Yamamoto, Enyu Imai, Shoichi Maruyama, Hitoshi Yokoyama, Hitoshi Sugiyama, Kosaku Nitta, Tatsuo Tsukamoto, Shunya Uchida, Asami Takeda, Toshinobu Sato, Takashi Wada, Hiroki Hayashi, Yasuhiro Akai, Megumu Fukunaga, Kazuhiko Tsuruya, Kosuke Masutani, Tsuneo Konta, Tatsuya Shoji, Takeyuki Hiramatsu, Shunsuke Goto, Hirofumi Tamai, Saori Nishio, Arimasa Shirasaki, Kojiro Nagai, Kunihiro Yamagata, Hajime Hasegawa, Hideo Yasuda, Shizunori Ichida, Tomohiko Naruse, Tomoya Nishino, Hiroshi Sobajima, Satoshi Tanaka, Toshiyuki Akahori, Takafumi Ito, Yoshio Terada, Ritsuko Katafuchi, Shouichi Fujimoto, Hirokazu Okada, Eiji Ishimura, Junichiro J Kazama, Keiju Hiromura, Tetsushi Mimura, Satoshi Suzuki, Yosuke Saka, Tadashi Sofue, Yusuke Suzuki, Yugo Shibagaki, Kiyoki Kitagawa, Kunio Morozumi, Yoshiro Fujita, Makoto Mizutani, Takashi Shigematsu, Naoki Kashihara, Hiroshi Sato, Seiichi Matsuo, Ichiei Narita, Yoshitaka Isaka

Clinical and experimental nephrology　Vol. 24　No. 6　p. 526-540　2020/06　Research paper (scientific journal)

Lithocholic acid increases intestinal phosphate and calcium absorption in a vitamin D receptor dependent but transcellular pathway independent manner.

Nobuhiro Hashimoto, Isao Matsui, Satoshi Ishizuka, Kazunori Inoue, Ayumi Matsumoto, Karin Shimada, Shota Hori, Dong Geun Lee, Seiichi Yasuda, Yusuke Katsuma, Sachio Kajimoto, Yohei Doi, Satoshi Yamaguchi, Keiichi Kubota, Tatsufumi Oka, Yusuke Sakaguchi, Yoshitsugu Takabatake, Takayuki Hamano, Yoshitaka Isaka

Kidney international　Vol. 97　No. 6　p. 1164-1180　2020/06

Prognostic value of hypochloremia versus hyponatremia among patients with chronic kidney disease-a retrospective cohort study.

Keiichi Kubota, Yusuke Sakaguchi, Takayuki Hamano, Tatsufumi Oka, Satoshi Yamaguchi, Karin Shimada, Ayumi Matsumoto, Nobuhiro Hashimoto, Daisuke Mori, Isao Matsui, Yoshitaka Isaka

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association　Vol. 35　No. 6　p. 987-994　2020/06/01　Research paper (scientific journal)

d-Amino acids and kidney diseases

Tomonori Kimura, Atsushi Hesaka, Yoshitaka Isaka

Clinical and Experimental Nephrology　Vol. 24　No. 5　p. 404-410　2020/05　Research paper (scientific journal)

【CKDの病態理解と新規治療法開発の現況】CKDの病態形成とオートファジー

猪阪 善隆

Pharma Medica　Vol. 38　No. 5　p. 33-35　2020/05　Research paper (scientific journal)

FGF23と心筋障害

松井 功, 猪阪 善隆

腎臓内科　Vol. 11　No. 5　p. 576-580　2020/05　Research paper (scientific journal)

Autophagy protects kidney from phosphate-induced mitochondrial injury.

Ryuta Fujimura, Takeshi Yamamoto, Yoshitsugu Takabatake, Atsushi Takahashi, Tomoko Namba-Hamano, Satoshi Minami, Shinsuke Sakai, Jun Matsuda, Atsushi Hesaka, Hiroaki Yonishi, Jun Nakamura, Isao Matsui, Taiji Matsusaka, Fumio Niimura, Motoko Yanagita, Yoshitaka Isaka

Biochemical and biophysical research communications　Vol. 524　No. 3　p. 636-642　2020/04/09　Research paper (scientific journal)

高尿素血症による血管石灰化メカニズム

松井 功, 森 大輔, 猪阪 善隆

腎臓内科　Vol. 11　No. 4　p. 436-441　2020/04　Research paper (scientific journal)

Drinking frequency modifies an association between salt intake and blood pressure: A cohort study.

Ryuichi Yoshimura, Ryohei Yamamoto, Maki Shinzawa, Ryohei Tomi, Shingo Ozaki, Yoshiyuki Fujii, Takafumi Ito, Kazuaki Tanabe, Yasuaki Moriguchi, Yoshitaka Isaka, Toshiki Moriyama

Journal of clinical hypertension (Greenwich, Conn.)　Vol. 22　No. 4　p. 649-655　2020/04　Research paper (scientific journal)

Body mass index modifies the association between frequency of alcohol consumption and incidence of hypertension in men but not in women: a retrospective cohort study.

Daiki Nishigaki, Ryohei Yamamoto, Maki Shinzawa, Yoshiki Kimura, Yoshiyuki Fujii, Katsunori Aoki, Ryohei Tomi, Shingo Ozaki, Ryuichi Yoshimura, Manabu Taneike, Kaori Nakanishi, Makoto Nishida, Keiko Yamauchi-Takihara, Yoshitaka Isaka, Toshiki Moriyama

Hypertension research : official journal of the Japanese Society of Hypertension　Vol. 43　No. 4　p. 322-330　2020/04　Research paper (scientific journal)

Hidden Hypocalcemia as a Risk Factor for Cardiovascular Events and All-Cause Mortality among Patients Undergoing Incident Hemodialysis.

Satoshi Yamaguchi, Takayuki Hamano, Yohei Doi, Tatsufumi Oka, Sachio Kajimoto, Keiichi Kubota, Seiichi Yasuda, Karin Shimada, Ayumi Matsumoto, Nobuhiro Hashimoto, Yusuke Sakaguchi, Isao Matsui, Yoshitaka Isaka

Scientific reports　Vol. 10　No. 1　p. 4418-4418　2020/03/10　Research paper (scientific journal)

Diabetic Kidney Disease 新しい概念とその治療戦略

猪阪 善隆

日本内科学会雑誌　Vol. 109　No. 3　p. 526-531　2020/03　Research paper (scientific journal)

造影剤腎症ガイドライン2018

猪阪 善隆

腎臓内科　Vol. 11　No. 3　p. 332-338　2020/03　Research paper (scientific journal)

Sleep debt and prevalence of proteinuria in subjects with short sleep duration on weekdays: a cross-sectional study.

Katsunori Aoki, Ryohei Yamamoto, Maki Shinzawa, Yoshiki Kimura, Hiroyoshi Adachi, Yoshiyuki Fujii, Ryohei Tomi, Kaori Nakanishi, Manabu Taneike, Makoto Nishida, Takashi Kudo, Keiko Yamauchi-Takihara, Yoshitaka Isaka, Toshiki Moriyama

Clinical and experimental nephrology　Vol. 24　No. 2　p. 143-150　2020/02　Research paper (scientific journal)

"Pseudo-empty pelvis" in a pre-dialysis patient.

Ayumi Matsumoto, Isao Matsui, Yusuke Sakaguchi, Harumi Kitamura, Maki Shinzawa, Chikako Monden, Atsushi Takahashi, Yoshitsugu Takabatake, Yoshitaka Isaka

Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis　Vol. 40　No. 4　p. 896860819899579-896860819899579　2020/01/17　Research paper (scientific journal)

Metabolic effects of RUBCN/Rubicon deficiency in kidney proximal tubular epithelial cells.

Jun Matsuda, Atsushi Takahashi, Yoshitsugu Takabatake, Shinsuke Sakai, Satoshi Minami, Takeshi Yamamoto, Ryuta Fujimura, Tomoko Namba-Hamano, Hiroaki Yonishi, Jun Nakamura, Tomonori Kimura, Jun-Ya Kaimori, Isao Matsui, Masatomo Takahashi, Motonao Nakao, Yoshihiro Izumi, Takeshi Bamba, Taiji Matsusaka, Fumio Niimura, Motoko Yanagita, Tamotsu Yoshimori, Yoshitaka Isaka

Autophagy　Vol. 16　No. 10　p. 1-16　2020/01/16　Research paper (scientific journal)

Recurrence of Proliferative Glomerulonephritis with Monoclonal Immunoglobulin G Deposits with a Striated Ultrastructure

Tomoko Namba-Hamano, Takayuki Hamano, Ryoichi Imamura, Yutaka Yamaguchi, Masahiro Kyo, Hiroaki Yonishi, Atsushi Takahashi, Masataka Kawamura, Shigeaki Nakazawa, Taigo Kato, Toyofumi Abe, Miyaji Kyakuno, Yoshitsugu Takabatake, Norio Nonomura, Yoshitaka Isaka

Nephron　Vol. 144　No. 1　p. 43-48　2020　Research paper (scientific journal)

「家族性尿細管間質腎炎(ADTKD)」 ADTKD-MUC1を中心として

貝森 淳哉, 猪阪 善隆

BIO Clinica　Vol. 35　No. 1　p. 78-82　2020/01　Research paper (scientific journal)

D-Serの体内動態評価は腎臓病診療に有用である

部坂 篤, 猪阪 善隆, 木村 友則

D-アミノ酸学会誌　Vol. 9　No. 1　p. 1-6　2020　Research paper (scientific journal)

Guideline on the use of iodinated contrast media in patients with kidney disease 2018.

Yoshitaka Isaka, Hiromitsu Hayashi, Kazutaka Aonuma, Masaru Horio, Yoshio Terada, Kent Doi, Yoshihide Fujigaki, Hideo Yasuda, Taichi Sato, Tomoyuki Fujikura, Ryohei Kuwatsuru, Hiroshi Toei, Ryusuke Murakami, Yoshihiko Saito, Atsushi Hirayama, Toyoaki Murohara, Akira Sato, Hideki Ishii, Tadateru Takayama, Makoto Watanabe, Kazuo Awai, Seitaro Oda, Takamichi Murakami, Yukinobu Yagyu, Nobuhiko Joki, Yasuhiro Komatsu, Takamasa Miyauchi, Yugo Ito, Ryo Miyazawa, Yoshihiko Kanno, Tomonari Ogawa, Hiroki Hayashi, Eri Koshi, Tomoki Kosugi, Yoshinari Yasuda

Japanese journal of radiology　Vol. 38　No. 1　p. 3-46　2020/01　Research paper (scientific journal)

Guideline on the use of iodinated contrast media in patients with kidney disease 2018.

Yoshitaka Isaka, Hiromitsu Hayashi, Kazutaka Aonuma, Masaru Horio, Yoshio Terada, Kent Doi, Yoshihide Fujigaki, Hideo Yasuda, Taichi Sato, Tomoyuki Fujikura, Ryohei Kuwatsuru, Hiroshi Toei, Ryusuke Murakami, Yoshihiko Saito, Atsushi Hirayama, Toyoaki Murohara, Akira Sato, Hideki Ishii, Tadateru Takayama, Makoto Watanabe, Kazuo Awai, Seitaro Oda, Takamichi Murakami, Yukinobu Yagyu, Nobuhiko Joki, Yasuhiro Komatsu, Takamasa Miyauchi, Yugo Ito, Ryo Miyazawa, Yoshihiko Kanno, Tomonari Ogawa, Hiroki Hayashi, Eri Koshi, Tomoki Kosugi, Yoshinari Yasuda

Clinical and experimental nephrology　Vol. 24　No. 1　p. 1-44　2020/01　Research paper (scientific journal)

Successful management of fetal hemolytic disease due to strong anti-Rh17 with plasma exchange and intrauterine transfusion in a woman with the D-- phenotype.

Kazuya Mimura, Masayuki Endo, Atsushi Takahashi, Yohei Doi, Mikiko Sakuragi, Tomoko Kiyokawa, Hidetoshi Taniguchi, Yasuji Kitabatake, Mika Handa, Takuji Tomimatsu, Yoshiaki Tomiyama, Yoshitaka Isaka, Tadashi Kimura

International journal of hematology　Vol. 111　No. 1　p. 149-154　2020/01　Research paper (scientific journal)

【腎泌尿器疾患のゲノム医療の進歩】慢性腎臓病とGWAS

松井 功, 猪阪 善隆

腎臓内科・泌尿器科　Vol. 10　No. 6　p. 494-498　2019/12　Research paper (scientific journal)

Guideline on the Use of Iodinated Contrast Media in Patients With Kidney Disease 2018.

Yoshitaka Isaka, Hiromitsu Hayashi, Kazutaka Aonuma, Masaru Horio, Yoshio Terada, Kent Doi, Yoshihide Fujigaki, Hideo Yasuda, Taichi Sato, Tomoyuki Fujikura, Ryohei Kuwatsuru, Hiroshi Toei, Ryusuke Murakami, Yoshihiko Saito, Atsushi Hirayama, Toyoaki Murohara, Akira Sato, Hideki Ishii, Tadateru Takayama, Makoto Watanabe, Kazuo Awai, Seitaro Oda, Takamichi Murakami, Yukinobu Yagyu, Nobuhiko Joki, Yasuhiro Komatsu, Takamasa Miyauchi, Yugo Ito, Ryo Miyazawa, Yoshihiko Kanno, Tomonari Ogawa, Hiroki Hayashi, Eri Koshi, Tomoki Kosugi, Yoshinari Yasuda

Circulation journal : official journal of the Japanese Circulation Society　Vol. 83　No. 12　p. 2572-2607　2019/11/25　Research paper (scientific journal)

Dynamics of D-serine reflected the recovery course of a patient with rapidly progressive glomerulonephritis.

Atsushi Hesaka, Keiko Yasuda, Shinsuke Sakai, Hiroaki Yonishi, Tomoko Namba-Hamano, Atsushi Takahashi, Masayuki Mizui, Kenji Hamase, Rakan Matsui, Masashi Mita, Masaru Horio, Yoshitaka Isaka, Tomonori Kimura

CEN case reports　Vol. 8　No. 4　p. 297-300　2019/11　Research paper (scientific journal)

腎障害患者におけるヨード造影剤使用に関するガイドライン2018

猪阪 善隆, 林 宏光, 青沼 和隆, 斎藤 能彦, 平山 篤志, 室原 豊明, 桑鶴 良平, 粟井 和夫, 村上 卓道, 菅野 義彦, 小松 康宏, 藤垣 嘉秀, 堀尾 勝, 佐藤 明, 高山 忠輝, 渡邉 真言, 石井 秀樹, 村上 隆介, 柳生 行伸, 藤榮 博史, 尾田 済太郎, 寺田 典生, 安田 日出夫, 常喜 信彦, 小川 智也, 林 宏樹, 藤倉 知行, 佐藤 太一, 土井 研人, 宮内 隆政, 伊藤 雄伍, 宮沢 亮, 古志 衣里, 小杉 智規, 安田 宜成, 興梠 征典, 鳴海 善文, 対馬 義人, 木村 剛, 玉木 長良, 島袋 朋子, 「腎障害患者におけるヨード造影剤使用に関するガイドライン」作成委員会, 日本腎臓学会, 日本医学放射線学会, 日本循環器学会

日本腎臓学会誌　Vol. 61　No. 7　p. 933-1081　2019/10　Research paper (scientific journal)

【嚢胞性腎疾患】常染色体優性遺伝性尿細管間質性腎疾患(ADTKD)

貝森 淳哉, 猪阪 善隆

日本腎臓学会誌　Vol. 61　No. 7　p. 1108-1112　2019/10　Research paper (scientific journal)

Low erythropoietin levels predict faster renal function decline in diabetic patients with anemia: a prospective cohort study.

Yohei Fujita, Yohei Doi, Takayuki Hamano, Masahiro Hatazaki, Yutaka Umayahara, Yoshitaka Isaka, Yoshiharu Tsubakihara

Scientific reports　Vol. 9　No. 1　p. 14871-14871　2019/10　Research paper (scientific journal)

5-ALA/SFC enhances HO-1 expression through the MAPK/Nrf2 antioxidant pathway and attenuates murine tubular epithelial cell apoptosis.

Liu C, Fujino M, Zhu S, Isaka Y, Ito H, Takahashi K, Nakajima M, Tanaka T, Zhu P, Li XK

FEBS open bio　2019/09　Research paper (scientific journal)

Low magnesium diet aggravates phosphate-induced kidney injury.

Yusuke Sakaguchi, Takayuki Hamano, Isao Matsui, Tatsufumi Oka, Satoshi Yamaguchi, Keiichi Kubota, Karin Shimada, Ayumi Matsumoto, Nobuhiro Hashimoto, Yoshitaka Isaka

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association　Vol. 34　No. 8　p. 1310-1319　2019/08/01　Research paper (scientific journal)

【既存のガイドラインを透析患者にどう活用するか】造影剤腎症

猪阪 善隆

臨床透析　Vol. 35　No. 8　p. 1101-1106　2019/07　Research paper (scientific journal)

日本腎臓学会 サルコペニア・フレイルを合併した保存期CKDの食事療法の提言

鈴木 芳樹, 猪阪 善隆, 荒木 信一, 佐藤 弘恵, 細島 康宏, 小尾 佳嗣, 蒲澤 秀門, 武田 尚子, 清野 裕, 門脇 孝, 窪田 直人, 菅野 義彦, 宇都宮 一典, 葛谷 雅文, 渡邉 潤, サルコペニア・フレイルを合併したCKDの食事療法検討WG, 日本病態栄養学会, 日本栄養療法協議会, 日本透析医学会, 日本糖尿病学会, 日本老年医学会, 日本栄養士会, 日本腎臓学会

日本透析医学会雑誌　Vol. 52　No. 7　p. 401-431　2019/07　Research paper (scientific journal)

サルコペニア・フレイルを合併した保存期CKDの食事療法の提言

鈴木 芳樹, 猪阪 善隆, 荒木 信一, 佐藤 弘恵, 細島 康宏, 小尾 佳嗣, 蒲澤 秀門, 武田 尚子, 清野 裕, 門脇 孝, 窪田 直人, 菅野 義彦, 宇都宮 一典, 葛谷 雅文, 渡邉 潤, 日本腎臓学会, サルコペニア・フレイルを合併したCKDの食事療法検討WG

日本腎臓学会誌　Vol. 61　No. 5　p. 525-555　2019/07

【医薬品副作用学(第3版)下-薬剤の安全使用アップデート-】臓器・系統別副作用各論 重大な副作用を中心に 腎臓 造影剤腎症

猪阪 善隆

日本臨床　Vol. 77　No. 増刊4 医薬品副作用学(下)　p. 113-118　2019/07　Research paper (scientific journal)

Proteinuria-associated renal magnesium wasting leads to hypomagnesemia: a common electrolyte abnormality in chronic kidney disease.

Tatsufumi Oka, Takayuki Hamano, Yusuke Sakaguchi, Satoshi Yamaguchi, Keiichi Kubota, Masamitsu Senda, Sayoko Yonemoto, Karin Shimada, Ayumi Matsumoto, Nobuhiro Hashimoto, Daisuke Mori, Chikako Monden, Atsushi Takahashi, Yoshitsugu Obi, Ryohei Yamamoto, Yoshitsugu Takabatake, Jun-Ya Kaimori, Toshiki Moriyama, Masaru Horio, Isao Matsui, Yoshitaka Isaka

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association　Vol. 34　No. 7　p. 1154-1162　2019/07/01　Research paper (scientific journal)

【指定難病ペディア 2019】個別の指定難病 腎・泌尿器系 一次性ネフローゼ症候群[指定難病222]

猪阪 善隆

日本医師会雑誌　Vol. 148　No. 特別1　p. S244-S246　2019/06　Research paper (scientific journal)

A Randomized Trial of Magnesium Oxide and Oral Carbon Adsorbent for Coronary Artery Calcification in Predialysis CKD.

Yusuke Sakaguchi, Takayuki Hamano, Yoshitsugu Obi, Chikako Monden, Tatsufumi Oka, Satoshi Yamaguchi, Isao Matsui, Nobuhiro Hashimoto, Ayumi Matsumoto, Karin Shimada, Yoshitsugu Takabatake, Atsushi Takahashi, Jun-Ya Kaimori, Toshiki Moriyama, Ryohei Yamamoto, Masaru Horio, Koichi Yamamoto, Ken Sugimoto, Hiromi Rakugi, Yoshitaka Isaka

Journal of the American Society of Nephrology : JASN　Vol. 30　No. 6　p. 1073-1085　2019/06　Research paper (scientific journal)

Proximal Tubule Autophagy Differs in Type 1 and 2 Diabetes.

Shinsuke Sakai, Takeshi Yamamoto, Yoshitsugu Takabatake, Atsushi Takahashi, Tomoko Namba-Hamano, Satoshi Minami, Ryuta Fujimura, Hiroaki Yonishi, Jun Matsuda, Atsushi Hesaka, Isao Matsui, Taiji Matsusaka, Fumio Niimura, Motoko Yanagita, Yoshitaka Isaka

Journal of the American Society of Nephrology : JASN　Vol. 30　No. 6　p. 929-945　2019/06　Research paper (scientific journal)

VEGF-A Links Angiolymphoid Hyperplasia With Eosinophilia (ALHE) to THSD7A Membranous Nephropathy: A Report of 2 Cases.

Ayumi Matsumoto, Isao Matsui, Tomoko Namba, Yusuke Sakaguchi, Hitoshi Mizuno, Yuki Shirayama, Karin Shimada, Nobuhiro Hashimoto, Yohei Doi, Satoshi Yamaguchi, Keiichi Kubota, Tatsufumi Oka, Daisuke Mori, Shinichi Akiyama, Takayuki Hamano, Masayuki Mizui, Yoshitsugu Takabatake, Tetsuya Kaneko, Yoshitaka Isaka

American journal of kidney diseases : the official journal of the National Kidney Foundation　Vol. 73　No. 6　p. 880-885　2019/06　Research paper (scientific journal)

糖尿病性腎症の存在下でも可能な、DTI MRIによる腎臓繊維化の撮影法の確立

貝森 淳哉, 余川 隆, 市丸 直嗣, 高原 史郎, 猪阪 善隆

JSMI Report　Vol. 12　No. 2　p. 149-149　2019/05　Research paper (scientific journal)

【慢性腎臓病の管理と今後の展望-新しいガイドラインを考慮して】オートファジーと慢性腎臓病

猪阪 善隆

カレントテラピー　Vol. 37　No. 5　p. 492-496　2019/05　Research paper (scientific journal)

【今、糸球体疾患を考える】一次性糸球体疾患 微小変化型ネフローゼ症候群

猪阪 善隆

腎と透析　Vol. 86　No. 5　p. 547-550　2019/05　Research paper (scientific journal)

【腎栄養学再訪】たんぱく質制限の理論的根拠

猪阪 善隆

腎と透析　Vol. 86　No. 4　p. 400-404　2019/04　Research paper (scientific journal)

病態と関連メカニズム 高尿酸血症による腎障害メカニズム

猪阪 善隆

循環plus　Vol. 19　No. 4　p. 10-12　2019/04　Research paper (scientific journal)

Assessment of renal function in living kidney donors before and after nephrectomy: A Japanese prospective, observational cohort study.

Yoichi Kakuta, Ryoichi Imamura, Masayoshi Okumi, Masaru Horio, Yoshitaka Isaka, Naotsugu Ichimaru, Shiro Takahara, Norio Nonomura, Kazunari Tanabe

International journal of urology : official journal of the Japanese Urological Association　Vol. 26　No. 4　p. 499-505　2019/04　Research paper (scientific journal)

Tolvaptan Efficiently Reduces Intracellular Fluid: Working Toward a Potential Treatment Option for Cellular Edema.

Hiroaki Kawabata, Hirotsugu Iwatani, Yuko Yamamichi, Keiko Shirahase, Naoko Nagai, Yoshitaka Isaka

Internal medicine (Tokyo, Japan)　Vol. 58　No. 5　p. 639-642　2019/03　Research paper (scientific journal)

D-Serine reflects kidney function and diseases.

Atsushi Hesaka, Shinsuke Sakai, Kenji Hamase, Tatsuhiko Ikeda, Rakan Matsui, Masashi Mita, Masaru Horio, Yoshitaka Isaka, Tomonori Kimura

Scientific reports　Vol. 9　No. 1　p. 5104-5104　2019/03　Research paper (scientific journal)

Suppression of autophagic activity by Rubicon is a signature of aging.

Shuhei Nakamura, Masaki Oba, Mari Suzuki, Atsushi Takahashi, Tadashi Yamamuro, Mari Fujiwara, Kensuke Ikenaka, Satoshi Minami, Namine Tabata, Kenichi Yamamoto, Sayaka Kubo, Ayaka Tokumura, Kanako Akamatsu, Yumi Miyazaki, Tsuyoshi Kawabata, Maho Hamasaki, Koji Fukui, Kazunori Sango, Yoshihisa Watanabe, Yoshitsugu Takabatake, Tomoya S Kitajima, Yukinori Okada, Hideki Mochizuki, Yoshitaka Isaka, Adam Antebi, Tamotsu Yoshimori

Nature communications　Vol. 10　No. 1　p. 847-847　2019/02/19　Research paper (scientific journal)

【マグネシウム代謝-その新たな臨床的意義】腎疾患とマグネシウム マグネシウムの補充はCKD治療の選択肢となるか

猪阪 善隆, 坂口 悠介

腎と透析　Vol. 86　No. 2　p. 240-243　2019/02　Research paper (scientific journal)

【心不全(第2版)中-最新の基礎・臨床研究の進歩-】血液浄化療法 体外限外濾過法(ECUM)を用いた急性血液浄化療法

猪阪 善隆

日本臨床　Vol. 77　No. 増刊1 心不全(中)　p. 491-497　2019/02　Research paper (scientific journal)

Safety profile of baricitinib in Japanese patients with active rheumatoid arthritis with over 1.6 years median time in treatment: An integrated analysis of Phases 2 and 3 trials.

Harigai M, Takeuchi T, Smolen JS, Winthrop KL, Nishikawa A, Rooney TP, Saifan CG, Issa M, Isaka Y, Akashi N, Ishii T, Tanaka Y

Modern rheumatology　Vol. 30　No. 1　p. 36-43　2019/02　Research paper (scientific journal)

Satb1 regulates the effector program of encephalitogenic tissue Th17 cells in chronic inflammation.

Yasuda K, Kitagawa Y, Kawakami R, Isaka Y, Watanabe H, Kondoh G, Kohwi-Shigematsu T, Sakaguchi S, Hirota K

Nature communications　Vol. 10　No. 1　2019/02　Research paper (scientific journal)

【腎臓・高血圧診療・研究のアップデート】造影剤腎症up-to-date

猪阪 善隆

循環器内科　Vol. 85　No. 1　p. 53-59　2019/01　Research paper (scientific journal)

5-aminolaevulinic acid (ALA), enhances heme oxygenase (HO)-1 expression and attenuates tubulointerstitial fibrosis and renal apoptosis in chronic cyclosporine nephropathy.

Liu C, Zhu P, Fujino M, Isaka Y, Ito H, Takahashi K, Nakajima M, Tanaka T, Zhuang J, Li XK

Biochemical and biophysical research communications　Vol. 508　No. 2　p. 583-589　2019/01　Research paper (scientific journal)

Parathyroid hormone and premature thymus ageing in patients with chronic kidney disease.

Kenichiro Iio, Daijiro Kabata, Rei Iio, Yosuke Imai, Masaki Hatanaka, Hiroki Omori, Yoshihiko Hoshida, Yukihiko Saeki, Ayumi Shintani, Takayuki Hamano, Yoshitaka Isaka, Yutaka Ando

Scientific reports　Vol. 9　No. 1　p. 813-813　2019/01　Research paper (scientific journal)

Severe Osteomalacia with Dent Disease Caused by a Novel Intronic Mutation of the CLCN5 gene.

Ayumi Matsumoto, Isao Matsui, Takayasu Mori, Yusuke Sakaguchi, Masayuki Mizui, Yoshiyasu Ueda, Atsushi Takahashi, Yohei Doi, Karin Shimada, Satoshi Yamaguchi, Keiichi Kubota, Nobuhiro Hashimoto, Tatsufumi Oka, Yoshitsugu Takabatake, Eisei Sohara, Takayuki Hamano, Shinichi Uchida, Yoshitaka Isaka

Internal medicine (Tokyo, Japan)　Vol. 57　No. 24　p. 3603-3610　2018/12/15　Research paper (scientific journal)

【エビデンスに基づく新しい腎臓病診療】AKIマネージメント 腎障害患者におけるヨード造影剤使用に関するガイドライン2018

猪阪 善隆

最新医学　Vol. 73　No. 12　p. 1588-1593　2018/12　Research paper (scientific journal)

透析患者における骨ミネラル代謝異常の進展および治療効果を規定する遺伝子多型の同定

山口 慧, 小尾 佳嗣, 濱野 高行, 坂口 悠介, 下村 明弘, 難波 倫子, 三上 聡司, 西 紀, 田中 元子, 嘉元 章人, 小尾 靖江, 友杉 直久, 椿原 美治, 猪阪 善隆

日本透析医会雑誌　Vol. 33　No. 3　p. 521-526　2018/12　Research paper (scientific journal)

Regional variations in immunosuppressive therapy in patients with primary nephrotic syndrome: the Japan nephrotic syndrome cohort study.

Yamamoto R, Imai E, Maruyama S, Yokoyama H, Sugiyama H, Nitta K, Tsukamoto T, Uchida S, Takeda A, Sato T, Wada T, Hayashi H, Akai Y, Fukunaga M, Tsuruya K, Masutani K, Konta T, Shoji T, Hiramatsu T, Goto S, Tamai H, Nishio S, Shirasaki A, Nagai K, Yamagata K, Hasegawa H, Yasuda H, Ichida S, Naruse T, Fukami K, Nishino T, Sobajima H, Tanaka S, Akahori T, Ito T, Yoshio T, Katafuchi R, Fujimoto S, Okada H, Ishimura E, Kazama JJ, Hiromura K, Mimura T, Suzuki S, Saka Y, Sofue T, Suzuki Y, Shibagaki Y, Kitagawa K, Morozumi K, Fujita Y, Mizutani M, Shigematsu T, Kashihara N, Sato H, Matsuo S, Narita I, Isaka Y

Clinical and experimental nephrology　Vol. 22　No. 6　p. 1266-1280　2018/12　Research paper (scientific journal)

Sleep Quality and Sleep Duration with CKD are Associated with Progression to ESKD.

Ryohei Yamamoto, Maki Shinzawa, Yoshitaka Isaka, Etsuko Yamakoshi, Enyu Imai, Yasuo Ohashi, Akira Hishida

Clinical journal of the American Society of Nephrology : CJASN　Vol. 13　No. 12　p. 1825-1832　2018/12　Research paper (scientific journal)

Effect of Oral Alfacalcidol on Clinical Outcomes in Patients Without Secondary Hyperparathyroidism Receiving Maintenance Hemodialysis: The J-DAVID Randomized Clinical Trial

Tetsuo Shoji, Masaaki Inaba, Masafumi Fukagawa, Ryoichi Ando, Masanori Emoto, Hisako Fujii, Akira Fujimori, Mitsuru Fukui, Hiroki Hase, Tetsuya Hashimoto, Hideki Hirakata, Hirokazu Honda, Tatsuo Hosoya, Yuji Ikari, Daijo Inaguma, Toru Inoue, Yoshitaka Isaka, Kunitoshi Iseki, Eiji Ishimura, Noritomo Itami, Chiharu Ito, Toshitaka Kakuta, Toru Kawai, Hideki Kawanishi, Shuzo Kobayashi, Junko Kumagai, Kiyoshi Maekawa, Ikuto Masakane, Jun Minakuchi, Koji Mitsuiki, Takashi Mizuguchi, Satoshi Morimoto, Toyoaki Murohara, Tatsuya Nakatani, Shigeo Negi, Shinichi Nishi, Mitsushige Nishikawa, Tetsuya Ogawa, Kazumichi Ohta, Takayasu Ohtake, Mikio Okamura, Senji Okuno, Takashi Shigematsu, Toshitsugu Sugimoto, Masashi Suzuki, Hideki Tahara, Yoshiaki Takemoto, Kenji Tanaka, Yoshihiro Tominaga, Yoshiharu Tsubakihara, Yoshihiro Tsujimoto, Kazuhiko Tsuruya, Shinichiro Ueda, Yuzo Watanabe, Kunihiro Yamagata, Tomoyuki Yamakawa, Shozo Yano, Keitaro Yokoyama, Noriaki Yorioka, Minoru Yoshiyama, Yoshiki Nishizawa

JAMA - Journal of the American Medical Association　Vol. 320　No. 22　p. 2325-2334　2018/12　Research paper (scientific journal)

【CKD-MBD】CKD-MBD新しい話題 FGF23とKlotho

猪阪 善隆, 松井 功

日本透析医学会雑誌　Vol. 51　No. 11　p. 665-669　2018/11　Research paper (scientific journal)

慢性腎臓病地域連携勉強会の実際と今後の展望

佐藤 浩美, 福本 のりえ, 鈴木 尚代, 松本 稔子, 新沢 真紀, 北村 温美, 猪阪 善隆

大阪CAPD研究会会誌　Vol. 31　p. 6-13　2018/11　Research paper (scientific journal)

反復する腹膜炎の原因としてカテーテル接合不良が疑われた腹膜透析患者の1例

森田 将史, 新沢 真紀, 余西 洋明, 富 量平, 土井 洋平, 高橋 篤史, 上田 仁康, 北村 温美, 水井 理之, 猪阪 善隆

大阪CAPD研究会会誌　Vol. 31　p. 21-27　2018/11　Research paper (scientific journal)

【タンパク質・核酸の分子修飾】細胞外での分子修飾 細胞外基質/その他 カルバモイル化

猪阪 善隆

生体の科学　Vol. 69　No. 5　p. 518-519　2018/10　Research paper (scientific journal)

CKD(慢性腎臓病)慢性腎臓病のこれまでと今後 最新の実地診療のポイントの整理と活用 CKDの評価法

猪阪 善隆

Medical Practice　Vol. 35　No. 10　p. 1529-1532　2018/10　Research paper (scientific journal)

Alcohol consumption and incidence of proteinuria: a retrospective cohort study.

Kimura Y, Yamamoto R, Shinzawa M, Isaka Y, Iseki K, Yamagata K, Tsuruya K, Yoshida H, Fujimoto S, Asahi K, Moriyama T, Watanabe T

Clinical and experimental nephrology　Vol. 22　No. 5　p. 1133-1142　2018/10　Research paper (scientific journal)

【水電解質代謝の五角関係】水・ナトリウム代謝の五角関係 トピックス 肝腎症候群の病態

猪阪 善隆

腎と透析　Vol. 85　No. 3　p. 393-396　2018/09　Research paper (scientific journal)

【老年医学(下)-基礎・臨床研究の最新動向-】高齢者の臓器別疾患 腎疾患 高齢者の腎疾患

猪阪 善隆

日本臨床　Vol. 76　No. 増刊7 老年医学(下)　p. 378-382　2018/08　Research paper (scientific journal)

Clinical features and pathogenesis of membranoproliferative glomerulonephritis: a nationwide analysis of the Japan renal biopsy registry from 2007 to 2015

Nakagawa Naoki, Hasebe Naoyuki, Hattori Motoshi, Nagata Michio, Yokoyama Hitoshi, Sato Hiroshi, Sugiyama Hitoshi, Shimizu Akira, Isaka Yoshitaka, Maruyama Shoichi, Narita Ichiei

CLINICAL AND EXPERIMENTAL NEPHROLOGY　Vol. 22　No. 4　p. 797-807-807　2018/08　Research paper (scientific journal)

Targeting TGF-β Signaling in Kidney Fibrosis.

Isaka Y

International journal of molecular sciences　Vol. 19　No. 9　2018/08

Kidney Allograft Histology in Recipients with Transplantation Vintage Longer than 10 Years

Namba-Hamano Tomoko, Kyo Masahiro, Hamano Takayuki, Yamaguchi Yutaka, Kawamura Masataka, Nakazawa Shigeaki, Kato Taigo, Abe Toyofumi, Imamura Ryoichi, Ichimaru Naotsugu, Takahara Shiro, Nonomura Norio, Isaka Yoshitaka

TRANSPLANTATION　Vol. 102　2018/07

Protein carbamylation exacerbates vascular calcification.

Daisuke Mori, Isao Matsui, Akihiro Shimomura, Nobuhiro Hashimoto, Ayumi Matsumoto, Karin Shimada, Satoshi Yamaguchi, Tatsufumi Oka, Keiichi Kubota, Sayoko Yonemoto, Yusuke Sakaguchi, Atsushi Takahashi, Yasunori Shintani, Seiji Takashima, Yoshitsugu Takabatake, Takayuki Hamano, Yoshitaka Isaka

Kidney international　Vol. 94　No. 1　p. 72-90　2018/07　Research paper (scientific journal)

Cardiac hypertrophy elevates serum levels of fibroblast growth factor 23.

Isao Matsui, Tatsufumi Oka, Yasuo Kusunoki, Daisuke Mori, Nobuhiro Hashimoto, Ayumi Matsumoto, Karin Shimada, Satoshi Yamaguchi, Keiichi Kubota, Sayoko Yonemoto, Tomoaki Higo, Yusuke Sakaguchi, Yoshitsugu Takabatake, Takayuki Hamano, Yoshitaka Isaka

Kidney international　Vol. 94　No. 1　p. 60-71　2018/07　Research paper (scientific journal)

Tolvaptan promotes urinary excretion of sodium and urea: a retrospective cohort study

Satoshi Minami, Takayuki Hamano, Hirotsugu Iwatani, Masayuki Mizui, Yoshiki Kimura, Yoshitaka Isaka

CLINICAL AND EXPERIMENTAL NEPHROLOGY　Vol. 22　No. 3　p. 550-561　2018/06　Research paper (scientific journal)

【腎と透析ベッドサイド検査事典】(第3章)アミノ酸検査 アミノ酸分析

猪阪 善隆

腎と透析　Vol. 84　No. 増刊　p. 106-107　2018/05　Research paper (scientific journal)

WEEKEND CATCH-UP SLEEP AND PREVALENCE OF PROTEINURIA: A CROSS-SECTIONAL STUDY

Aoki Katsunori, Yamamoto Ryohei, Shinzawa Maki, Kimura Yoshiki, Fujii Yoshiyuki, Nakanishi Kaori, Koseki Masahiro, Nishida Makoto, Takihara Keiko, Isaka Yoshitaka, Moriyama Toshiki

NEPHROLOGY DIALYSIS TRANSPLANTATION　Vol. 33　2018/05

ESTIMATED GFR REDUCTION RATE AT 30 DAYS AFTER KIDNEY DONATION AS A SURROGATE OF RENAL OUTCOME IN KIDNEY DONORS

Namba-Hamano Tomoko, Hamano Takayuki, Matsui Isao, Kawamura Masataka, Nakazawa Shigeaki, Kato Taigo, Abe Toyofumi, Imamura Ryoichi, Kaimori Junya, Ichimaru Naotsugu, Takahara Shiro, Nonomura Norio, Isaka Yoshitaka

NEPHROLOGY DIALYSIS TRANSPLANTATION　Vol. 33　2018/05

Magnesium and Progression of Chronic Kidney Disease: Benefits Beyond Cardiovascular Protection?

Yusuke Sakaguchi, Takayuki Hamano, Yoshitaka Isaka

Advances in chronic kidney disease　Vol. 25　No. 3　p. 274-280　2018/05　Research paper (scientific journal)

【高齢者医療ハンドブック-高齢者医療におけるダイバーシティへの対応】(第I章)高齢者の特性を理解する〜生理機能の加齢変化〜 腎機能

猪阪 善隆

内科　Vol. 121　No. 4　p. 597-600　2018/04　Research paper (scientific journal)

【腎疾患診療の未来 最新知見のエッセンシャル】腎臓基礎研究の最先端 オートファジーと腎疾患

高畠 義嗣, 山本 毅士, 猪阪 善隆

診断と治療　Vol. 106　No. 4　p. 452-457　2018/04　Research paper (scientific journal)

【高齢者の腎泌尿器疾患治療】慢性腎臓病

猪阪 善隆

腎と透析　Vol. 84　No. 3　p. 438-442　2018/03

【腎と糖尿病:変革期の診断と治療】【DKDの基礎】オートファジー

猪阪 善隆, 高橋 篤史, 高畠 義嗣

腎と透析　Vol. 84　No. 2　p. 156-160　2018/02　Research paper (scientific journal)

Antioxidant role of autophagy in maintaining the integrity of glomerular capillaries.

Jun Matsuda, Tomoko Namba, Yoshitsugu Takabatake, Tomonori Kimura, Atsushi Takahashi, Takeshi Yamamoto, Satoshi Minami, Shinsuke Sakai, Ryuta Fujimura, Jun-Ya Kaimori, Isao Matsui, Takayuki Hamano, Yoko Fukushima, Keiko Matsui, Tomoyoshi Soga, Yoshitaka Isaka

Autophagy　Vol. 14　No. 1　p. 53-65　2018　Research paper (scientific journal)

【Practical Issues of PCI 2018】造影剤腎症

猪阪 善隆

Coronary Intervention　Vol. 14　No. 1　p. 111-115　2018/01　Research paper (scientific journal)

Rationale, design, and characteristics of a trial to evaluate the new phosphate iron-based binder sucroferric oxyhydroxide in dialysis patients with the goal of advancing the practice of E.B.M. (EPISODE)

Isaka, Y., Fujii, H., Tsujimoto, Y., Teramukai, S., Hamano, T.

Clinical and Experimental Nephrology　Vol. 22　No. 4　p. 967-972　2018　Research paper (scientific journal)

Red cell distribution width and renal outcome in patients with non-dialysis-dependent chronic kidney disease.

Sayoko Yonemoto, Takayuki Hamano, Naohiko Fujii, Karin Shimada, Satoshi Yamaguchi, Ayumi Matsumoto, Keiichi Kubota, Nobuhiro Hashimoto, Tatsufumi Oka, Masamitsu Senda, Yusuke Sakaguchi, Isao Matsui, Yoshitaka Isaka

PloS one　Vol. 13　No. 6　2018　Research paper (scientific journal)

Magnesium in Hemodialysis Patients: A New Understanding of the Old Problem.

Sakaguchi Y, Hamano T, Isaka Y

Contributions to nephrology　Vol. 196　p. 58-63　2018　Research paper (scientific journal)

Prognostic Significance of Asymptomatic Brain Natriuretic Peptide Elevation at Nephrology Referral in Patients with Chronic Kidney Disease.

Hayashi T, Yasuda K, Kimura T, Sasaki K, Shimada K, Hashimoto N, Isaka Y

American journal of nephrology　Vol. 48　No. 3　p. 205-213　2018　Research paper (scientific journal)

【異なる2病態の免疫学的関連】IgA腎症と扁桃炎

猪阪 善隆

炎症と免疫　Vol. 26　No. 1　p. 14-18　2017/12　Research paper (scientific journal)

CKD診療のピットフォール ファブリー病など希少疾患を含めて

猪阪 善隆

大阪府内科医会会誌　Vol. 26　No. 2　p. 153-156　2017/12　Research paper (scientific journal)

Adaptor protein is a new therapeutic target in chronic kidney disease

Yoshitaka Isaka

KIDNEY INTERNATIONAL　Vol. 92　No. 6　p. 1312-1314　2017/12　Research paper (scientific journal)

Analysis of an ADTKD family with a novel frameshift mutation in MUC1 reveals characteristic features of mutant MUC1 protein

Satoko Yamamoto, Jun-Ya Kaimori, Takuji Yoshimura, Tomoko Namba, Atsuko Imai, Kaori Kobayashi, Ryoichi Imamura, Naotsugu Ichimaru, Kazuto Kato, Akihiro Nakaya, Shiro Takahara, Yoshitaka Isaka

NEPHROLOGY DIALYSIS TRANSPLANTATION　Vol. 32　No. 12　p. 2010-2017　2017/12　Research paper (scientific journal)

【水・電解質異常 体内恒常性の維持にまつわる温故知新】治療 実地医家は最新治療をどのように実践すべきか 高齢者の低ナトリウム血症

猪阪 善隆

Medical Practice　Vol. 34　No. 11　p. 1866-1870　2017/11　Research paper (scientific journal)

腎疾患を伴う2型糖尿病患者の治療戦略

古家 大祐, 阿部 雅紀, 脇野 修, 猪阪 善隆

Diabetes Update　Vol. 6　No. 4　p. 196-206　2017/11　Research paper (scientific journal)

Anion Gap as a Determinant of Ionized Fraction of Divalent Cations in Hemodialysis Patients.

Sakaguchi Y, Hamano T, Kubota K, Oka T, Yamaguchi S, Matsumoto A, Hashimoto N, Mori D, Obi Y, Matsui I, Isaka Y

Clinical journal of the American Society of Nephrology : CJASN　2017/11　Research paper (scientific journal)

Antioxidant role of autophagy in maintaining the integrity of glomerular capillaries.

atsuda J, Namba T, Takabatake Y, Kimura T, Takahashi A, Yamamoto T, Minami S, Sakai S, Fujimura R, Kaimori JY, Matsui I, Hamano T, Fukushima Y, Matsui K, Soga T, Isaka Y

Autophagy　Vol. 14　No. 1　p. 53-65　2017/11　Research paper (scientific journal)

Lipophagy maintains energy homeostasis in the kidney proximal tubule during prolonged starvation.

Satoshi Minami, Takeshi Yamamoto, Yoshitsugu Takabatake, Atsushi Takahashi, Tomoko Namba, Jun Matsuda, Tomonori Kimura, Jun-Ya Kaimori, Isao Matsui, Takayuki Hamano, Hiroaki Takeda, Masatomo Takahashi, Yoshihiro Izumi, Takeshi Bamba, Taiji Matsusaka, Fumio Niimura, Yoshitaka Isaka

Autophagy　Vol. 13　No. 10　p. 1629-1647　2017/10/03　Research paper (scientific journal)

【透析療法のNew Concept-各種ガイドラインに基づく診療のポイント】標準的なドライウェイトの設定法

猪阪 善隆

臨床泌尿器科　Vol. 71　No. 11　p. 892-895　2017/10　Research paper (scientific journal)

【腎泌尿器と凝固線溶系】透析患者における凝固・線溶系異常

猪阪 善隆

腎臓内科・泌尿器科　Vol. 6　No. 4　p. 306-310　2017/10　Research paper (scientific journal)

家族性尿細管間質腎炎(ADTKD)

貝森 淳哉, 高原 史郎, 猪阪 善隆

細胞　Vol. 49　No. 10　p. 511-514　2017/09　Research paper (scientific journal)

CKD患者のトータルケアと最近の話題 フレイルとの関連性

猪阪 善隆

日本臨床内科医会会誌　Vol. 32　No. 3　p. 453-453　2017/09　Research paper (scientific journal)

透析患者における低栄養とフレイル

猪阪 善隆

大阪透析研究会会誌　Vol. 35　No. 2　p. 95-98　2017/09　Research paper (scientific journal)

Autosomal dominant tubulointerstitial disease

Vol. 49　No. 10　p. 511-514　2017/09　Research paper (scientific journal)

The association of alcohol and smoking with CKD in a Japanese nationwide cross-sectional survey

Ayako Matsumoto, Yasuyuki Nagasawa, Ryohei Yamamoto, Maki Shinzawa, Yukiko Hasuike, Takahiro Kuragano, Yoshitaka Isaka, Takeshi Nakanishi, Kunitoshi Iseki, Kunihiro Yamagata, Kazuhiko Tsuruya, Hideaki Yoshida, Shouichi Fujimoto, Koichi Asahi, Toshiki Moriyama, Tsuyoshi Watanabe

HYPERTENSION RESEARCH　Vol. 40　No. 8　p. 771-778　2017/08　Research paper (scientific journal)

NEDD4-family E3 ligase dysfunction due to PKHD1/Pkhd1 defects suggests a mechanistic model for ARPKD pathobiology

Jun-ya Kaimori, Cheng-Chao Lin, Patricia Outeda, Miguel A. Garcia-Gonzalez, Luis F. Menezes, Erum A. Hartung, Ao Li, Guanqing Wu, Hideaki Fujita, Yasunori Sato, Yasuni Nakanuma, Satoko Yamamoto, Naotsugu Ichimaru, Shiro Takahara, Yoshitaka Isaka, Terry Watnick, Luiz F. Onuchic, Lisa M. Guay-Woodford, Gregory G. Germino

SCIENTIFIC REPORTS　Vol. 7　No. 1　2017/08　Research paper (scientific journal)

Visualization of kidney fibrosis in diabetic nephropathy by long diffusion tensor imaging MRI with spin-echo sequence.

Kaimori JY, Isaka Y, Hatanaka M, Yamamoto S, Ichimaru N, Fujikawa A, Shibata H, Fujimori A, Miyoshi S, Yokawa T, Kuroda K, Moriyama T, Rakugi H, Takahara S

Scientific reports　Vol. 7　No. 1　p. 5731-5731　2017/07　Research paper (scientific journal)

Critical renal adverse event induced by nivolumab therapy in a stage IV melanoma patient

Aya Tanaka, Kuniko Ikinaga, Eiji Kiyohara, Atsushi Tanemura, Mari Wataya-Kaneda, Ryuta Fujimura, Masayuki Mizui, Yoshitaka Isaka, Ichiro Katayama

JOURNAL OF DERMATOLOGY　Vol. 44　No. 6　p. 727-728　2017/06

腎疾患とオートファジー オートファジーと腎臓の老化、虚血性腎障害

猪阪 善隆

臨床病理　Vol. 65　No. 6　p. 661-666　2017/06　Research paper (scientific journal)

CKD対策としての健診・検診の意義と病診連携 多発性嚢胞腎の診断と治療を含めて

猪阪 善隆

大阪府内科医会会誌　Vol. 26　No. 1　p. 86-86　2017/06　Research paper (scientific journal)

Autophagy of Kidney Associated with Senescence and Ischemic Injury

Vol. 65　No. 6　p. 661-666　2017/06　Research paper (scientific journal)

医学と医療の最前線 腎疾患進行防御機構としてのオートファジー

猪阪 善隆, 山本 毅士, 難波 倫子, 高橋 篤史, 木村 友則, 高畠 義嗣

日本内科学会雑誌　Vol. 106　No. 6　p. 1206-1211　2017/06　Research paper (scientific journal)

NIGHT SHIFT FREQUENCY AND INCIDENCE OF PROTEINURIA: A RETROSPECTIVE COHORT STUDY

Yamamto Ryohei, Shinzawa Maki, Kimura Yoshiki, Fujii Yoshiyuki, Aoki Katsunori, Nakanishi Kaori, Koseki Masahiro, Nishida Makoto, Nishida Makoto, Yamauchi-Takihara Keiko, Isaka Yoshitaka, Moriyama Toshiki

NEPHROLOGY DIALYSIS TRANSPLANTATION　Vol. 32　2017/05

High-Fat Diet-Induced Lysosomal Dysfunction and Impaired Autophagic Flux Contribute to Lipotoxicity in the Kidney

Takeshi Yamamoto, Yoshitsugu Takabatake, Atsushi Takahashi, Tomonori Kimura, Tomoko Namba, Jun Matsuda, Satoshi Minami, Jun-Ya Kaimori, Isao Matsui, Taiji Matsusaka, Fumio Niimura, Motoko Yanagita, Yoshitaka Isaka

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY　Vol. 28　No. 5　p. 1534-1551　2017/05　Research paper (scientific journal)

Autophagy Inhibits the Accumulation of Advanced Glycation End Products by Promoting Lysosomal Biogenesis and Function in the Kidney Proximal Tubules

Atsushi Takahashi, Yoshitsugu Takabatake, Tomonori Kimura, Ikuko Maejima, Tomoko Namba, Takeshi Yamamoto, Jun Matsuda, Satoshi Minami, Jun-ya Kaimori, Isao Matsui, Taiji Matsusaka, Fumio Niimura, Tamotsu Yoshimori, Yoshitaka Isaka

DIABETES　Vol. 66　No. 5　p. 1359-1372　2017/05　Research paper (scientific journal)

【高尿酸血症・糖尿病の臓器(腎)障害と治療Up to Date】高尿酸血症によるインフラマソームと慢性腎臓病

猪阪 善隆

尿酸と血糖　Vol. 3　No. 2　p. 70-73　2017/04　Research paper (scientific journal)

An unusual case of acute kidney injury after colonoscopy Reply

Nobuhiro Hashimoto, Isao Matsui, Tomoko Namba, Tatsufumi Oka, Daisuke Mori, Yusuke Sakaguchi, Masayuki Mizui, Takayuki Hamano, Yoshitsugu Takabatake, Yoshitaka Isaka

KIDNEY INTERNATIONAL　Vol. 91　No. 4　p. 989-990　2017/04　Research paper (scientific journal)

The Authors Reply

Nobuhiro Hashimoto, Isao Matsui, Tomoko Namba, Tatsufumi Oka, Daisuke Mori, Yusuke Sakaguchi, Masayuki Mizui, Takayuki Hamano, Yoshitsugu Takabatake, Yoshitaka Isaka

Kidney International　Vol. 91　No. 4　p. 989-990　2017/04　Research paper (scientific journal)

Cardiac troponin T elevation at dialysis initiation is associated with all-cause and cardiovascular mortality on dialysis in patients without diabetic nephropathy

Hayashi T, Kimura T, Yasuda K, Sasaki K, Obi Y, Rakugi H, Isaka Y

Clinical and Experimental Nephrology　Vol. 21　No. 2　p. 333-341　2017/04

High-pressure carbon monoxide preserves rat kidney grafts from apoptosis and inflammation.

Abe T, Yazawa K, Fujino M, Imamura R, Hatayama N, Kakuta Y, Tsutahara K, Okumi M, Ichimaru N, Kaimori JY, Isaka Y, Seki K, Takahara S, Li XK, Nonomura N

Laboratory investigation; a journal of technical methods and pathology　Vol. 97　No. 4　p. 468-477　2017/04　Research paper (scientific journal)

Clinical features of CKD-MBD in Japan: cohort studies and registry.

Hamano T, Sakaguchi Y, Fujii N, Isaka Y

Clinical and experimental nephrology　Vol. 21　No. Suppl 1　p. 9-20　2017/03　Research paper (scientific journal)

【腹水管理の最近の進歩】トルバプタンの使用について 腎臓内科の立場から

貝森 淳哉, 猪阪 善隆, 高原 史郎

肝臓　Vol. 58　No. 2　p. 85-90　2017/02　Research paper (scientific journal)

Effects of Magnesium on the Phosphate Toxicity in Chronic Kidney Disease: Time for Intervention Studies

Yusuke Sakaguchi, Takayuki Hamano, Yoshitaka Isaka

NUTRIENTS　Vol. 9　No. 2　2017/02　Research paper (scientific journal)

Autophagy and Cancer

Yoshitaka Isaka, Tomonori Kimura, Yoshitsugu Takabatake, Atsushi Takahashi

Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging　Vol. 11　p. 237-244　2017/01/18　Part of collection (book)

【ビタミンDとカルシウム・リン代謝update】CKD-MBDにおけるビタミンDとFGF23

松井 功, 猪阪 善隆

THE BONE　Vol. 30　No. 4　p. 375-379　2017/01　Research paper (scientific journal)

Tips for use of tolvaptan —from a nephrologist to gastroenterologists—

Jun-Ya Kaimori, Yoshitaka Isaka, Shiro Takahara

Acta Hepatologica Japonica　Vol. 58　No. 2　p. 85-90　2017　Research paper (scientific journal)

The SONG (Salt intake and OrigiN from General foods) Study - A Large-scale Survey of the Eating Habits and Dietary Salt Intake in the Working-age Population

Yoshitaka Isaka, Toshiki Moriyama, Kiyomi Kanda

INTERNAL MEDICINE　Vol. 56　No. 18　p. 2423-2430　2017　Research paper (scientific journal)

Stagnation of autophagy: A novel mechanism of renal lipotoxicity

Yoshitsugu Takabatake, Takeshi Yamamoto, Yoshitaka Isaka

AUTOPHAGY　Vol. 13　No. 4　p. 775-776　2017　Research paper (scientific journal)

Polymer-brush-afforded SPIO Nanoparticles Show a Unique Biodistribution and MR Imaging Contrast in Mouse Organs

Ting Chen, Yuki Mori, Chizuko Inui-Yamamoto, Yutaka Komai, Yoshiyuki Tago, Shinichi Yoshida, Yoshitsugu Takabatake, Yoshitaka Isaka, Kohji Ohno, Yoshichika Yoshioka

MAGNETIC RESONANCE IN MEDICAL SCIENCES　Vol. 16　No. 4　p. 275-283　2017　Research paper (scientific journal)

Autophagy and kidney inflammation

Tomonori Kimura, Yoshitaka Isaka, Tamotsu Yoshimori

AUTOPHAGY　Vol. 13　No. 6　p. 997-1003　2017　Research paper (scientific journal)

Diffusion Tensor Imaging MRI With Spin-Echo Sequence and Long-Duration Measurement for Evaluation of Renal Fibrosis in a Rat Fibrosis Model.

Kaimori JY, Isaka Y, Hatanaka M, Yamamoto S, Ichimaru N, Fujikawa A, Shibata H, Fujimori A, Miyoshi S, Yokawa T, Kuroda K, Moriyama T, Rakugi H, Takahara S, Transplantation, proceedings

Transplantation Proceedings　Vol. 49　No. 1　p. 145-152　2017　Research paper (scientific journal)

【慢性腎臓病(CKD)治療の最前線-生活習慣病への新たなアプローチ-】生活習慣とCKD進展とのクロストーク CKDと睡眠障害とのクロストーク

猪阪 善隆, 坂口 悠介

最新医学　Vol. 71　No. 12　p. 2447-2452　2016/12　Research paper (scientific journal)

高齢者における薬物療法のガイドライン 腎疾患

猪阪 善隆

医薬品医療機器レギュラトリーサイエンス　Vol. 47　No. 12　p. 848-851　2016/12　Research paper (scientific journal)

Crosstalk Between CKD and Sleep Disturbance

Vol. 71　No. 12　p. 2447-2452　2016/12　Research paper (scientific journal)

【在宅透析-光と影】通院困難患者に対する透析療法 通院困難患者に対するCAPD実施上の現状と課題

猪阪 善隆, 北村 温美

腎と透析　Vol. 81　No. 5　p. 817-820　2016/11　Research paper (scientific journal)

コホート研究を目的とした情報処理システム コホートメーカー

山本 陵平, 新澤 真紀, 守山 敏樹, 猪阪 善隆, 杉山 斉, 丸山 彰一, 中島 直樹, 岡田 浩一, 岡田 美保子, 柏原 直樹

医療情報学連合大会論文集　Vol. 36回　No. 1　p. 544-545　2016/11

Cohort maker:a novel data management system for cohort studies.

Yamamoto Ryohei, Shinzawa Maki, Moriyama Toshiki, Isaka Yoshitaka, Sugiyama Hitoshi, Maruyama Shoichi, Nakashima Naoki, Okada Hirokazu, Okada Mihoko, Kashihara Naoki

Vol. 36　No. Suppl.　p. 544-545　2016/11　Research paper (scientific journal)

Intravenous Vitamin B6 Increases Resistance to Erythropoiesis-Stimulating Agents in Hemodialysis Patients: A Randomized Controlled Trial.

Obi Y, Mikami S, Hamano T, Obi Y, Tanaka H, Shimomura A, Rakugi H, Inoue T, Isaka Y, Jou, the official journal of, the, Council on Renal, Nutrition of, the, National, Kidney Foundation

Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation　Vol. 26　No. 6　p. 380-390　2016/11

ヒヤリハットから学ぶ人工臓器の安全管理 レジリエンス・エンジニアリング(Safety-II)の観点から病院と在宅治療の安全を考える

北村 温美, 坂井 瑠実, 猪阪 善隆, 中島 和江

人工臓器　Vol. 45　No. 2　p. S-48　2016/10　Research paper (scientific journal)

Epidermal growth factor as a prognostic biomarker in chronic kidney diseases

Yoshitaka Isaka

Annals of Translational Medicine　Vol. 4　2016/10/01　Research paper (scientific journal)

Clozapine improved the syndrome of inappropriate antidiuretic hormone secretion (SIADH) in a patient with treatment-resistant schizophrenia

Fujimoto M, Hashimoto R, Yamamori H, Yasuda Y, Ohi K, Iwatani H, Isaka Y, Takeda M

Psychiatry Clin Neurosci　Vol. 70　No. 10　p. 469-469　2016/10

スクロオキシ水酸化鉄(PA21)はイオン化カルシウム濃度を上げる

中野 智香子, 門田 和之, 猪阪 善隆, 濱野 高行

大阪透析研究会会誌　Vol. 34　No. 2　p. 243-244　2016/09

【高齢者の腹膜透析-assisted PDの現実と可能性】腎不全患者医療とPD 行政の考え方

猪阪 善隆

臨床透析　Vol. 32　No. 10　p. 1237-1243　2016/09　Research paper (scientific journal)

An unusual case of acute kidney injury after colonoscopy

Nobuhiro Hashimoto, Isao Matsui, Tomoko Namba, Tatsufumi Oka, Daisuke Mori, Yusuke Sakaguchi, Masayuki Mizui, Takayuki Hamano, Yoshitsugu Takabatake, Yoshitaka Isaka

Kidney International　Vol. 90　No. 3　2016/09　Research paper (scientific journal)

Screening Tool for Older Persons' Appropriate Prescriptions in Japanese: Report of the Japan Geriatrics Society Working Group on "Guidelines for medical treatment and its safety in the elderly".

Kojima T, Mizukami K, Tomita N, Arai H, Ohrui T, Eto M, Takeya Y, Isaka Y, Rakugi H, Sudo N, Arai H, Aoki H, Horie S, Ishii S, Iwasaki K, Takayama S, Suzuki Y, Matsui T, Mizokami F, Furuta K, Geriatrics, gerontology international

Geriatrics & gerontology international　Vol. 16　No. 9　p. 983-1001　2016/09　Research paper (scientific journal)

ネフローゼ症候群Up To Date

猪阪 善隆

日本腎臓学会誌　Vol. 58　No. 6　p. 902-902　2016/08　Research paper (scientific journal)

Serum Uric Acid Level Predicts Progression of IgA Nephropathy in Females but Not in Males.

Nagasawa Y, Yamamoto R, Shoji T, Shinzawa M, Hasuike Y, Nagatoya K, Yamauchi A, Hayashi T, Kuragano T, Moriyama T, Isaka Y, Nakanishi T

PloS one　Vol. 11　No. 8　2016/08　Research paper (scientific journal)

【透析患者の体液管理】腎機能低下に伴う水・電解質排泄キャパシティ

猪阪 善隆

Fluid Management Renaissance　Vol. 6　No. 3　p. 211-216　2016/07　Research paper (scientific journal)

Hyperuricemia-induced inflammasome and kidney diseases

Yoshitaka Isaka, Yoshitsugu Takabatake, Atsushi Takahashi, Tatsuya Saitoh, Tamotsu Yoshimori

Nephrology Dialysis Transplantation　Vol. 31　No. 6　p. 890-896　2016/06/24　Research paper (scientific journal)

【腎と透析診療指針2016】(第18章)腎移植 腎移植患者の妊娠・分娩

猪阪 善隆

腎と透析　Vol. 80　No. 増刊　p. 744-746　2016/06　Research paper (scientific journal)

Mechanism-based Medicineに基づいたCKD診療

猪阪 善隆

大阪府内科医会会誌　Vol. 25　No. 1　p. 31-35　2016/05　Research paper (scientific journal)

PA21 ELEVATES PLASMA IONIZED CALCIUM LEVELS

Chikako Nakano, Yoshitaka Isaka, Takayuki Hamano

NEPHROLOGY DIALYSIS TRANSPLANTATION　Vol. 31　p. 1535-1535　2016/05　Research paper (scientific journal)

PROTEINURIA AND DIABETES MELLITUS AS RISK FACTORS OF HYPOMAGNESEMIA IN PATIENTS WITH CHRONIC KIDNEY DISEASE

Tatsufumi Oka, Takayuki Hamano, Masamitsu Senda, Sayoko Yonemoto, Yusuke Sakaguchi, Chikako Nakano, Yoshitaka Isaka

NEPHROLOGY DIALYSIS TRANSPLANTATION　Vol. 31　p. 73-73　2016/05　Research paper (scientific journal)

ALDOSTERONE PLAYS A ROLE IN THE PATHOGENESIS OF ECTOPIC CALCIFICATION IN CHRONIC KIDNEY DISEASE

Masamitsu Senda, Takayuki Hamano, Yusuke Sakaguchi, Yoshitaka Isaka, Toshiki Moriyama

NEPHROLOGY DIALYSIS TRANSPLANTATION　Vol. 31　p. 1457-1458　2016/05　Research paper (scientific journal)

IFI27 IN PERIPHERAL WHITE BLOOD CELLS IS A USEFUL MARKER FOR IGA NEPHROPATHY

Yasuyuki Nagasawa, Ouzaki Daisuke, Ryohei Yamamoto, Eri Muso, Maki Shinzawa, Kiyoko Yamamoto, Tomoko Kimura, Takeshi Nakanishi, Yoshitaka Isaka, Hiroshi Najima

NEPHROLOGY DIALYSIS TRANSPLANTATION　Vol. 31　p. 139-140　2016/05　Research paper (scientific journal)

EFFICACY OF STEROID STEROID THERAPY FOR IGA NEPHROPATHY THERAPY FOR IGA NEPHROPATHY

Yasuyuki Nagasawa, Rhouhei Yamamoto, Tatsuya Shouji, Maki Shinzawa, Tomoko Kimura, Kiyiko Yamamoto, Yukiko Hasuike, Katsuyuki Nagatoya, Atsushi Yamauchi, Terumasa Hayashi, Takayuki Kuragano, Toshiki Moriyama, Yoshitaka Isaka, Takeshi Nakanishi

NEPHROLOGY DIALYSIS TRANSPLANTATION　Vol. 31　p. 382-382　2016/05　Research paper (scientific journal)

FUNCTIONAL IRON DEFICIENCY AFFECTS PLATELET INCREASE AFTER HIGH-DOSE ERYTHROPOIETIN STIMULATING AGENTS THETAPY AMONG PREDIALYSIS CKD PATIENTS

Sayoko Yonemoto, Takayuki Hamano, Naohiko Fujii, Daisuke Hayashi, Isao Matsui, Yoshitaka Isaka

NEPHROLOGY DIALYSIS TRANSPLANTATION　Vol. 31　p. 193-193　2016/05　Research paper (scientific journal)

ALLOGRAFT HISTOLOGY IN PATIENTS WITH TRANSPLANTATION VINTAGE LONGER THAN 20 YEARS; TREMENDOUS EFFECTS OF DONOR AGE

Tomoko Namba, Masahiro Kyo, Takayuki Hamano, Yutaka Yamaguchi, Yoshitaka Isaka, Shiro Takahara

NEPHROLOGY DIALYSIS TRANSPLANTATION　Vol. 31　p. 1565-1566　2016/05　Research paper (scientific journal)

Identification of biomarkers for development of end-stage kidney disease in chronic kidney disease by metabolomic profiling.

Kimura T, Yasuda K, Yamamoto R, Soga T, Rakugi H, Hayashi T, Isaka Y, Scientific reports

Scientific reports　Vol. 6　2016/05　Research paper (scientific journal)

Chiral amino acid metabolomics for novel biomarker screening in the prognosis of chronic kidney disease.

Kimura T, Hamase K, Miyoshi Y, Yamamoto R, Yasuda K, Mita M, Rakugi H, Hayashi T, Isaka Y, Scientific reports

Scientific reports　Vol. 6　2016/05　Research paper (scientific journal)

Time-dependent dysregulation of autophagy: Implications in aging and mitochondrial homeostasis in the kidney proximal tubule.

Yamamoto T, Takabatake Y, Kimura T, Takahashi A, Namba T, Matsuda J, Minami S, Kaimori JY, Matsui I, Kitamura H, Matsusaka T, Niimura F, Yanagita M, Isaka Y, Rakugi H, Autophagy

Autophagy　Vol. 12　No. 5　p. 801-813　2016/05　Research paper (scientific journal)

【腎保護薬update】腎保護が期待される薬剤 ビタミンD

松井 功, 猪阪 善隆

腎と透析　Vol. 80　No. 4　p. 515-518　2016/04　Research paper (scientific journal)

IFI27 Is a Useful Genetic Marker for Diagnosis of Immunoglobulin A Nephropathy and Membranous Nephropathy Using Peripheral Blood.

Yasuyuki Nagasawa, Daisuke Okuzaki, Eri Muso, Ryohei Yamamoto, Maki Shinzawa, Yukako Iwasaki, Hirotsugu Iwatani, Takeshi Nakanishi, Yoshitaka Isaka, Hiroshi Nojima

PloS one　Vol. 11　No. 4　2016/04　Research paper (scientific journal)

Histone H4 lysine 20 acetylation is associated with gene repression in human cells.

Kaimori JY, Maehara K, Hayashi-Takanaka Y, Harada A, Fukuda M, Yamamoto S, Ichimaru N, Umehara T, Yokoyama S, Matsuda R, Ikura T, Nagao K, Obuse C, Nozaki N, Takahara S, Takao T, Ohkawa Y, Kimura H, Isaka Y

Scientific reports　Vol. 6　p. 24318-24318　2016/04　Research paper (scientific journal)

New mechanism leading to alleviation of salt-sensitive hypertension by a powerful angiotensin receptor blocker, azilsartan

Jun-Ya Kaimori, Masaki Hatanaka, Satoko Yamamoto, Naotsugu Ichimaru, Shiro Takahara, Yoshitaka Isaka, Hiromi Rakugi

Receptors & Clinical Investigation　Vol. 3　No. e1352　p. 1-5　2016/03　Research paper (scientific journal)

Clinical nephrology 水電解質異常 Vitamin D・リン代謝系と腎機能障害

松井 功, 濱野 高行, 猪阪 善隆

Annual Review腎臓　Vol. 2016　p. 164-168　2016/01　Research paper (scientific journal)

Innovative drug development for chronic kidney disease

Vol. 68　No. 3　p. 83-89,図巻頭1p　2016　Research paper (scientific journal)

Body Mass Index Modifies an Association between Self-Reported Regular Exercise and Proteinuria.

Nagasawa Y, Yamamoto R, Shinzawa M, Hasuike Y, Kuragano T, Isaka Y, Nakanishi T, Iseki K, Yamagata K, Tsuruya K, Yoshida H, Fujimoto S, Asahi K, Moriyama T, Watanabe T

Journal of atherosclerosis and thrombosis　Vol. 23　No. 4　p. 402-412　2016

Critical renal adverse event induced by nivolumab therapy in a stage IV melanoma patient.

Tanaka A, Ikinaga K, Kiyohara E, Tanemura A, Wataya-Kaneda M, Fujimura R, Mizui M, Isaka Y, Katayama I

J Dermatol　2016/01　Research paper (scientific journal)

Early nephrology referral 6 months before dialysis initiation can reduce early death but does not improve long-term cardiovascular outcome on dialysis

Hayashi T, Kimura T, Yasuda K, Sasaki K, Obi Y, Nagayama H, Ohno M, Uematsu K, Tamai T, Nishide T, Rakugi H, Isaka Y

Circulation Journal　Vol. 80　No. 4　p. 1008-1016　2016

Laparoscopy Reveals a Diversity of Peritoneal Change in Patients with Long-Term Vintage of Peritoneal Dialysis.

Sasaki K, Mizuno H, Iwamoto N, Imakita M, Yasuda K, Kimura T, Rakugi H, Isaka Y, Hayashi T, Blood purification

Blood purification　Vol. 41　No. 1-3　p. 48-54　2016

Azilsartan improves salt sensitivity by modulating the proximal tubular Na⁺-H⁺exchanger-3 in mice

Hatanaka M, Kaimori J.-Y, Yamamoto S, Matsui I, Hamano T, Takabatake Y, Ecelbarger C.M, Takahara S, Isaka Y, Rakugi H

PLoS ONE　Vol. 11　No. 1　2016

Association between density of coronary artery calcification and serum magnesium levels among patients with chronic kidney disease

Sakaguchi Y, Hamano T, Nakano C, Obi Y, Matsui I, Kusunoki Y, Mori D, Oka T, Hashimoto N, Takabatake Y, Takahashi A, Kaimori J.-Y, Moriyama T, Yamamoto R, Horio M, Sugimoto K, Yamamoto K, Rakugi H, Isaka Y

PLoS ONE　Vol. 11　No. 9　2016

生存解析を目的としたデータシート作成支援システムの開発

山本 陵平, 加藤エルテス 聡志, 栗山 実, 新澤 真紀, 猪阪 善隆, 守山 敏樹

医療情報学連合大会論文集　Vol. 35回　p. 614-615　2015/11

Excess 25-hydroxyvitamin D3 exacerbates tubulointerstitial injury in mice by modulating macrophage phenotype.

Kusunoki Y, Matsui I, Hamano T, Shimomura A, Mori D, Yonemoto S, Takabatake Y, Tsubakihara Y, St-Arnaud R, Isaka Y, Rakugi H, Kidney international

Kidney international　Vol. 88　No. 5　p. 1013-1029　2015/11

血管石灰化に対する食事療法

猪阪 善隆, 松井 功, 濱野 高行

The Lipid　2015/10　Research paper (scientific journal)

Magnesium modifies the association between serum phosphate and the risk of progression to end-stage kidney disease in patients with non-diabetic chronic kidney disease.

Sakaguchi Y, Iwatani H, Hamano T, Tomida K, Kawabata H, Kusunoki Y, Shimomura A, Matsui I, Hayashi T, Tsubakihara Y, Isaka Y, Rakugi H, Kidney international

Kidney international　Vol. 88　No. 4　p. 833-842　2015/10

高解像度DTI MR imaging法による腎線維化可視化の研究

貝森 淳哉, 猪阪 善隆, 畑中 雅喜, 山本 聡子, 市丸 直嗣, 藤川 昭彦, 柴田 洋, 藤森 明, 三好 荘介, 余川 隆, 黒田 輝, 守山 敏樹, 楽木 宏実, 高原 史郎

Organ Biology　Vol. 22　No. 3　p. 72-72　2015/10　Research paper (scientific journal)

ACE insertion/deletion polymorphism (rs1799752) modifies the renoprotective effect of renin-angiotensin system blockade in patients with IgA nephropathy.

Teranishi J, Yamamoto R, Nagasawa Y, Shoji T, Iwatani H, Okada N, Moriyama T, Yamauchi A, Tsubakihara Y, Imai E, Rakugi H, Isaka Y, Jou, st, JRAAS, vo

Journal of the renin-angiotensin-aldosterone system : JRAAS　Vol. 16　No. 3　p. 633-641　2015/09　Research paper (scientific journal)

オートファジー

猪阪 善隆, 高橋 篤史, 高畠 義嗣

腎臓内科・泌尿器科　2015/08　Research paper (scientific journal)

mTOR Complex Signaling through the SEMA4A-Plexin B2 Axis Is Required for Optimal Activation and Differentiation of CD8+ T Cells.

Ito D, Nojima S, Nishide M, Okuno T, Takamatsu H, Kang S, Kimura T, Yoshida Y, Morimoto K, Maeda Y, Hosokawa T, Toyofuku T, Ohshima J, Kamimura D, Yamamoto M, Murakami M, Morii E, Rakugi H, Isaka Y, Kumanogoh A, J

Journal of immunology (Baltimore, Md. : 1950)　Vol. 195　No. 3　p. 934-943　2015/08　Research paper (scientific journal)

Cancer Biology エピジェネティクスにおけるヒストンアセチル化の新展開新規ヒストン修飾H4K20acと遺伝子発現、細胞増殖について

貝森 淳哉, 市丸 直嗣, 猪阪 善隆, 楽木 宏実, 高原 史郎

Organ Biology　Vol. 22　No. 2　p. 79-81　2015/07　Research paper (scientific journal)

慢性腎不全血液透析患者の肝胆膵外科手術症例の検討

畑 知樹, 富丸 慶人, 江口 英利, 友國 晃, 浅岡 忠史, 和田 浩志, 川本 弘一, 丸橋 繁, 岩谷 博次, 猪阪 善隆, 森 正樹, 土岐 祐一郎, 永野 浩昭

日本肝胆膵外科学会・学術集会プログラム・抄録集　Vol. 27回　p. 569-569　2015/06

シクロスポリン投与中に腎障害出現し、腎盂腫瘍が指摘された紅皮症性乾癬の1例

宇都宮 綾乃, 林 美沙, 山岡 俊文, 谷 守, 山本 浩一, 木枕 舞, 今村 亮一, 猪阪 善隆, 片山 一朗

西日本皮膚科　Vol. 77　No. 3　p. 299-300　2015/06

Prevalence and prognostic implications of vitamin D deficiency in chronic kidney disease.

Obi Y, Hamano T, Isaka Y

Dis Markers.　2015/06　Research paper (scientific journal)

A pilot study of the effects of eplerenone add-on therapy in patients taking renin-angiotensin system blockers.

Kawada N, Isaka Y, Kitamura H, Rakugi H, Moriyama T, Jou, yst, JRAAS, vo

Journal of the renin-angiotensin-aldosterone system : JRAAS　Vol. 16　No. 2　p. 360-365　2015/06　Research paper (scientific journal)

Histochemical and immunoelectron microscopic analysis of ganglioside GM3 in human kidney.

Kaneko T, Tsubakihara Y, Fushimi H, Yamaguchi S, Takabatake Y, Rakugi H, Kawakami H, Isaka Y, Clinical, experimental nephrology, v

Clinical and experimental nephrology　Vol. 19　No. 3　p. 403-410　2015/06

THE ASSOCIATION OF beta-BLOCKER USE AND THE PROGRESSION OF RENAL FAILURE IN PATIENTS WITH CHRONIC KIDNEY DISEASE

Naohiko Fujii, Takayuki Hamano, Chikako Nakano, Satoshi Mikami, Yoshitsugu Obi, Noriyuki Okada, Yoshitaka Isaka

NEPHROLOGY DIALYSIS TRANSPLANTATION　Vol. 30　2015/05　Research paper (scientific journal)

RED CELL DISTRIBUTION WIDTH AMONG PATIENTS WITH CHRONIC KIDNEY DISEASE AND ITS CORRELATION WITH IRON INDICES

Sayoko Yonemoto, Takayuki Hamano, Naohiko Fujii, Isao Matsui, Yoshitaka Isaka

NEPHROLOGY DIALYSIS TRANSPLANTATION　Vol. 30　2015/05　Research paper (scientific journal)

OSTEOPOROSIS PATIENTS WITH HIGH BONE TURNOVER MARKER ARE MORE LIKELY TO DEVELOP HYPOCALCEMIA AFTER RECEIVING ANTI-RESORPTIVE THERAPY

Chikako Nakano, Takayuki Hamano, Isao Matsui, Hiromi Rakugi, Yoshitaka Isaka

NEPHROLOGY DIALYSIS TRANSPLANTATION　Vol. 30　2015/05　Research paper (scientific journal)

腎臓のアンチエイジング機構としてのオートファジー

高畠 義嗣, 猪阪 善隆, 守山 敏樹

泌尿器科　2015/05　Research paper (scientific journal)

Respiratory diseases and autophagy; autophagic inhibitors

ISAKA YOSHITAKA, KIMURA TOMONORI, TAKABATAKE YOSHITSUGU

Lung Perspect　Vol. 23　No. 2　p. 164-167　2015/05　Research paper (scientific journal)

特定健診における尿蛋白陽性率に対する飲酒量と喫煙の影響

松本 綾子, 長澤 康行, 山本 陵平, 新澤 真紀, 蓮池 由起子, 倉賀野 隆裕, 猪阪 善隆, 中西 健, 井関 邦敏, 山縣 邦弘, 鶴屋 和彦, 吉田 英昭, 藤元 昭一, 旭 浩一, 渡辺 毅, 守山 敏樹, 厚生労働科学研究費補助金「今後の特定健康診査・保健指導における慢性腎臓病(CKD)の位置付けに関する検討」

日本腎臓学会誌　Vol. 57　No. 3　p. 592-592　2015/04　Research paper (scientific journal)

女性において高尿酸血症はIgA腎症の進行予測因子である

長澤 康行, 山本 陵平, 新沢 真紀, 川田 早百合, 木田 有利, 八尋 真名, 倉賀野 隆裕, 勝二 達也, 林 晃正, 長門谷 克之, 山内 淳, 猪阪 善隆, 中西 健

日本腎臓学会誌　Vol. 57　No. 3　p. 576-576　2015/04　Research paper (scientific journal)

CD16+CD56+ cells are a potential culprit for hematuria in IgA nephropathy.

Iwatani H, Nagasawa Y, Yamamoto R, Iio K, Mizui M, Horii A, Kitahara T, Inohara H, Kumanogoh A, Imai E, Rakugi H, Isaka Y, Clinical, experimental nephrology, v

Clinical and experimental nephrology　Vol. 19　No. 2　p. 216-224　2015/04　Research paper (scientific journal)

New insights of histone acetylation in epigenetics ‒physiological significance of H4K20ac in gene expression and cell proliferation‒

Kaimori Junya, Ichimaru Naotsugu, Isaka Yoshitaka, Rakugi Hiromi, Takahara Shirou

Organ Biology　Vol. 22　No. 2　p. 181-183　2015　Research paper (scientific journal)

慢性腎臓病(CKD)の最新の治療 (特集 新たな腎臓病の知識・治療)

猪阪 善隆, 楽木 宏実

成人病と生活習慣病 : 日本成人病(生活習慣病)学会準機関誌　Vol. 45　No. 1　p. 64-69　2015/01　Research paper (scientific journal)

[Bone and Calcium Research Update 2015. Regulation of calcium in CKD].

Isaka Y, Rakugi H, Clinical calcium

Clinical calcium　Vol. 25　No. 1　p. 79-85　2015/01　Research paper (scientific journal)

Minimal change nephrotic syndrome which was most likely caused by chronic sinusitis

Iwatani H, Mori D, Yamamoto S, Nakano C, Yamamoto R, Masumura C, Shikina T, Imai T, Inohara H, Rakugi H, Isaka Y

Internal Medicine　Vol. 54　No. 18　p. 2373-2375　2015　Research paper (scientific journal)

Urine osmolarity predicts the body weight-reduction response to tolvaptan in chronic kidney disease patients: a retrospective, observational study.

Iwatani H, Kawabata H, Sakaguchi Y, Yamamoto R, Hamano T, Rakugi H, Isaka Y, Nephron, vo

Nephron　Vol. 130　No. 1　p. 8-12　2015

Role of meatbolic stress in cyclosporine-induced kidney tubular injury

TAKAHASHI ATSUSHI, KIMURA TOMONORI, TAKABATAKE YOSHITSUGU, ISAKA YOSHITAKA

Transplantation today　Vol. 27　No. 6　p. 511-514　2014/12　Research paper (scientific journal)

Clinical Outcomes and Vitamin D Status in Kidney Transplant Recipients

Vol. 2　No. 2　p. 153-159　2014/12　Research paper (scientific journal)

An association between serum γ-glutamyltransferase and proteinuria in drinkers and non-drinkers: a Japanese nationwide cross-sectional survey.

Ishigami T, Yamamoto R, Nagasawa Y, Isaka Y, Rakugi H, Iseki K, Yamagata K, Tsuruya K, Yoshida H, Fujimoto S, Asahi K, Kurahashi I, Ohashi Y, Moriyama T, Watanabe T, Clinical, experimental nephrology, v

Clinical and experimental nephrology　Vol. 18　No. 6　p. 899-910　2014/12　Research paper (scientific journal)

Cancer Biology エピジェネティクスにおけるヒストンアセチル化の新展開新規ヒストン修飾H4K20acと遺伝子発現、細胞増殖について

貝森 淳哉, 市丸 直嗣, 猪阪 善隆, 楽木 宏実, 高原 史郎

Organ Biology　Vol. 21　No. 3　p. 57-57　2014/10　Research paper (scientific journal)

Autophagic clearance of mitochondria in the kidney copes with metabolic acidosis.

Namba T, Takabatake Y, Kimura T, Takahashi A, Yamamoto T, Matsuda J, Kitamura H, Niimura F, Matsusaka T, Iwatani H, Matsui I, Kaimori J, Kioka H, Isaka Y, Rakugi H, Jour, al, American Society of Nephrology, JASN, v

Journal of the American Society of Nephrology : JASN　Vol. 25　No. 10　p. 2254-2266　2014/10　Research paper (scientific journal)

The authors reply.

Sakaguchi Y, Fujii N, Shoji T, Hayashi T, Rakugi H, Iseki K, Tsubakihara Y, Isaka Y, Committee of Renal, Data Registry of, the, Japanese, Society for Dialysis Therapy, Kidney international

Kidney international　Vol. 86　No. 4　p. 856-857　2014/10

Autophagy Guards Against Immunosuppression and Renal Ischemia-Reperfusion Injury in Renal Transplantation

Yoshitaka Isaka, Tomonori Kimura, Atsushi Takahashi, Yoshitsugu Takabatake

Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging　Vol. 5　p. 249-258　2014/09/24　Part of collection (book)

腎臓とオートファジー

猪阪 善隆, 高橋 篤史, 高畠 義嗣

Thrombosis Medicine　2014/09　Research paper (scientific journal)

Autophagy and the kidney: health and disease

Yoshitsugu Takabatake, Tomonori Kimura, Atsushi Takahashi, Yoshitaka Isaka

NEPHROLOGY DIALYSIS TRANSPLANTATION　Vol. 29　No. 9　p. 1639-1647　2014/09　Research paper (scientific journal)

Dietary L-lysine prevents arterial calcification in adenine-induced uremic rats.

Shimomura A, Matsui I, Hamano T, Ishimoto T, Katou Y, Takehana K, Inoue K, Kusunoki Y, Mori D, Nakano C, Obi Y, Fujii N, Takabatake Y, Nakano T, Tsubakihara Y, Isaka Y, Rakugi H, Jour, al, American Society of Nephrology, JASN, v

Journal of the American Society of Nephrology : JASN　Vol. 25　No. 9　p. 1954-1965　2014/09　Research paper (scientific journal)

【腹膜透析2014】腹膜透析患者の塩味覚感度に食習慣が及ぼす影響

岡本 千明, 新沢 真紀, 松本 稔子, 吉村 栄里, 中野 智香子, 山本 陵平, 長澤 康行, 北村 温美, 中西 健, 猪阪 善隆

腎と透析　Vol. 77　No. 別冊 腹膜透析2014　p. 379-380　2014/08　Research paper (scientific journal)

ネフローゼ症候群を呈する疾患の最新の診断・治療 成人発症の微小変化型ネフローゼ症候群について

新沢 真紀, 山本 陵平, 長澤 康行, 猪阪 善隆

日本腎臓学会誌　Vol. 56　No. 6　p. 675-675　2014/08　Research paper (scientific journal)

心停止後ラット腎臓のfunctional MRIを用いた詳細な障害の評価と腎移植後グラフト予後予測可能性

貝森淳哉, 岩井聡美, 小林英司, 畑中雅喜, 津田秀年, 小尾義嗣, 奥見雅由, 矢澤浩治, 市丸直嗣, 楽木宏美, 野々村祝夫, 猪阪善隆, 高原史郎

Organ Biol　Vol. 21　No. 2　p. 179-181　2014/07/10　Research paper (scientific journal)

The authors reply.

Sakaguchi Y, Fujii N, Shoji T, Hayashi T, Rakugi H, Iseki K, Tsubakihara Y, Isaka Y, Committee of Renal, Data Registry of, the, Japanese, Society for Dialysis Therapy, Kidney international

Kidney international　Vol. 86　No. 1　p. 212-213　2014/07

Comparison of Methylprednisolone Plus Prednisolone with Prednisolone Alone as Initial Treatment in Adult-Onset Minimal Change Disease: A Retrospective Cohort Study

Maki Shinzawa, Ryohei Yamamoto, Yasuyuki Nagasawa, Susumu Oseto, Daisuke Mori, Kodo Tomida, Terumasa Hayashi, Masaaki Izumi, Megumu Fukunaga, Atsushi Yamauchi, Yoshiharu Tsubakihara, Yoshitaka Isaka

CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY　Vol. 9　No. 6　p. 1040-1048　2014/06　Research paper (scientific journal)

ジュース摂取頻度は蛋白尿の発症予測因子である 後ろ向きコホート研究

山本 陵平, 新澤 真紀, 石神 敏博, 寺西 順哉, 川田 典孝, 西田 誠, 瀧原 圭子, 楽木 宏美, 猪阪 善隆, 守山 敏樹

日本腎臓学会誌　Vol. 56　No. 3　p. 290-290　2014/05　Research paper (scientific journal)

メチルプレドニゾロンパルスは微小変化型ネフローゼ症候群の再発を抑制する

新沢 真紀, 山本 陵平, 長澤 康行, 大瀬戸 奨, 森 大輔, 冨田 弘道, 林 晃正, 和泉 雅章, 福永 恵, 山内 淳, 椿原 美治, 猪阪 善隆

日本腎臓学会誌　Vol. 56　No. 3　p. 296-296　2014/05　Research paper (scientific journal)

IgA腎症患者において総コレステロールは独立した予後規定因子である

長澤 康行, 山本 陵平, 新沢 真紀, 濱畑 早百合, 木田 有利, 蓮池 由起子, 八尋 真名, 倉賀野 隆裕, 勝二 達也, 林 晃正, 長門谷 克行, 山内 淳, 猪阪 善隆, 中西 健

日本腎臓学会誌　Vol. 56　No. 3　p. 329-329　2014/05　Research paper (scientific journal)

維持透析患者における肺炎の起因菌および菌検出の因子の検討

佐々木 公一, 山口 慧, 部坂 篤, 酒井 晋介, 岩橋 恵理子, 藤本 拓, 南 聡, 楽木 宏実, 猪阪 善隆, 横山 建二

日本腎臓学会誌　Vol. 56　No. 4　p. 524-531　2014/05　Research paper (scientific journal)

THE EFFECTIVENESS OF INTRAVENOUS METHYLPREDNISOLONEIN IN ADULT-ONSET MINIMAL-CHANGE DISEASE: A RETROSPECTIVE COHORT STUDY

Yamamoto Ryohei, Shinzawa Maki, Nagasawa Yasuyuki, Oseto Susumu, Mori Daisuke, Tomida Kodo, Hayashi Terumasa, Izumi Masaaki, Fukunaga Megumu, Yamauchi Atsushi, Tsubakihara Yoshiharu, Isaka Yoshitaka

NEPHROLOGY　Vol. 19　p. 139-139　2014/05　Research paper (scientific journal)

TOTAL CHOLESTEROL IS INDEPENDET RISK FACTOR FOR PROGRESSION OF KIDNEY DISEASE IN IGA NEPRHROPATHY PATIENTS

Yasuyuki Nagasawa, Ryohei Yamamoto, Maki Shinzawa, Sayuri Hamahata, Aritoshi Kida, Mana Yahiro, Takayuki Kuragano, Tatsuya Shoji, Terumasa Hayashi, Katsuyuki Nagatoya, Atsushi Yamauchi, Yoshitaka Isaka, Takshi Nakanishi

NEPHROLOGY DIALYSIS TRANSPLANTATION　Vol. 29　p. 197-197　2014/05　Research paper (scientific journal)

TWO PHOSPHATURIC HORMONES PREDICT THE PROGRESSION OF ANEMIA IN PATIENTS WITH CKD

Chikako Nakano, Takayuki Hamano, Naohiko Fujii, Isao Matusi, Satoshi Mikami, Kodo Tomida, Daisuke Mori, Yasuo Kusunoki, Akihiro Shimomura, Yoshitsugu Obi, Terumasa Hayashi, Hiromi Rakugi, Yoshitaka Isaka, Yoshiharu Tsubakihara

NEPHROLOGY DIALYSIS TRANSPLANTATION　Vol. 29　p. 380-380　2014/05　Research paper (scientific journal)

SOFT DRINK CONSUMPTION AND PREDICTION OF PROTEINURIA: A RETROSPECTIVE COHORT STUDY

Yamamoto Ryohei, Shinzawa Maki, Ishigami Toshihiro, Teranishi Junya, Kawada Noritaka, Nishida Makoto, Yamauchi-Takihara Keiko, Rakugi Hiromi, Isaka Yoshitaka, Moriyama Toshiki

NEPHROLOGY　Vol. 19　p. 169-169　2014/05　Research paper (scientific journal)

MAXACALCITOL AMELIORATES PATHOLOGICAL LEFT VENTRICULAR HYPERTROPHY BY INHIBITING CALCINEURIN-NFAT PATHWAY IN RATS WITH CHRONIC KIDNEY DISEASE

Mori Daisuke, Inoue Kazunori, Hamano Takayuki, Matsui Isao, Shimomura Akihiro, Kusunoki Yasuo, Nakano Chikako, Obi Yoshitsugu, Tsubakihara Yoshiharu, Isaka Yoshitaka, Rakugi Hiromi

NEPHROLOGY　Vol. 19　p. 69-69　2014/05　Research paper (scientific journal)

EXCESSIVE 25-HYDOXYVITAMIN D EXACERBATES RENAL FIBROSIS IN MICE

Kusunoki Yasuo, Matsui Isao, Hamano Takayuki, Shimomura Akihiro, Mori Daisuke, Nakano Chikako, Obi Yoshitsugu, Inoue Kazunori, Tsubakihara Yoshiharu, Isaka Yoshitaka, Rakugi Hiromi

NEPHROLOGY　Vol. 19　p. 69-69　2014/05　Research paper (scientific journal)

Multidetector-row computed tomography is useful to evaluate the therapeutic effects of bisphosphonates in glucocorticoid-induced osteoporosis.

Inoue K, Hamano T, Nango N, Matsui I, Tomida K, Mikami S, Fujii N, Nakano C, Obi Y, Shimomura A, Kusunoki Y, Rakugi H, Isaka Y, Tsubakihara Y, of, neral, m

Journal of bone and mineral metabolism　Vol. 32　No. 3　p. 271-280　2014/05　Research paper (scientific journal)

Membranous nephropathy secondary to Graves' disease with deposits of thyroid peroxidase in an adult.

Sasaki K, Yasuda K, Nakanishi K, Rakugi H, Isaka Y, Yamato M

CEN case reports　Vol. 3　No. 1　p. 90-93　2014/05　Research paper (scientific journal)

[Acute kidney injury: progress in diagnosis and treatments. Topics: IV. Pathophysiology and treatments: 1. Contrast-induced acute kidney injury].

Isaka Y, Rakugi H, Nihon Naika, Gakkai, zasshi. The Journal of, the, Japanese, Society of Internal, Medicine

Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine　Vol. 103　No. 5　p. 1074-1080　2014/05

血性排液精査のため経PDカテーテル的に内視鏡検査を施行した腹膜透析の1例

新沢 真紀, 岩谷 博次, 川端 裕彰, 中野 智香子, 北村 温美, 楠 博, 樂木 宏実, 猪阪 善隆

大阪透析研究会会誌　Vol. 32　No. 1　p. 49-51　2014/03　Research paper (scientific journal)

血性排液を呈し経PDカテーテル的に腹腔内視鏡検査を施行した腹膜透析の1例

楠 博, 岩谷 博次, 新沢 真紀, 川端 裕彰, 中野 智香子, 北村 温美, 樂木 宏実, 猪阪 善隆

大阪透析研究会会誌　Vol. 32　No. 1　p. 99-100　2014/03　Research paper (scientific journal)

【診て考えて実践する-水・電解質管理と輸液】水・電解質異常の診断・管理に難渋した症例 シスプラチン投与後に低Na血症を呈した食道がん患者の一例

松田 潤, 猪阪 善隆, 山内 淳

Medicina　Vol. 51　No. 2　p. 321-324　2014/02　Research paper (scientific journal)

Vitamin D deficiency predicts decline in kidney allograft function: a prospective cohort study.

Obi Y, Hamano T, Ichimaru N, Tomida K, Matsui I, Fujii N, Okumi M, Kaimori JY, Yazawa K, Kokado Y, Nonomura N, Rakugi H, Takahara S, Isaka Y, Tsubakihara Y, The Journal of clinical endocrinology, metabolism

The Journal of clinical endocrinology and metabolism　Vol. 99　No. 2　p. 527-535　2014/02　Research paper (scientific journal)

Does hypomagnesemia predict faster progression of nondiabetic chronic kidney disease?

Sakaguchi Y, Tsubakihara Y, Rakugi H, Isaka Y, The American journal, of, medicine, o, p

The American journal of medicine　Vol. 127　No. 2　2014/02

腹膜透析患者に対するシナカルセト投与後の血清リン濃度の変化は残腎機能の影響を受ける(Residual renal function modifies the effect of cinacalcet on serum phosphorus)

小尾 佳嗣, 濱野 高行, 中野 智香子, 新澤 真紀, 冨田 弘道, 北村 温美, 松井 功, 猪阪 善隆, 椿原 美治

腎と骨代謝　Vol. 27　No. 1　p. 77-80　2014/01　Research paper (scientific journal)

Transplantation of Allogenic Fetal Membrane-Derived Mesenchymal Stem Cells Protects Against Ischemia/Reperfusion-Induced Acute Kidney Injury

Hidetoshi Tsuda, Kenichi Yamahara, Kentaro Otani, Masayoshi Okumi, Koji Yazawa, Jun-ya Kaimori, Akihiko Taguchi, Kenji Kangawa, Tomoaki Ikeda, Shiro Takahara, Yoshitaka Isaka

CELL TRANSPLANTATION　Vol. 23　No. 7　p. 889-899　2014　Research paper (scientific journal)

CD28スーパーアゴニストによる制御性T細胞増殖を介した治療効果

猪阪 善隆, 高畠義嗣

Annual Review腎臓2014　2014/01　Research paper (scientific journal)

Periodontal disease bacteria specific to tonsil in IgA nephropathy patients predicts the remission by the treatment.

Nagasawa Y, Iio K, Fukuda S, Date Y, Iwatani H, Yamamoto R, Horii A, Inohara H, Imai E, Nakanishi T, Ohno H, Rakugi H, Isaka Y, PloS one

PloS one　Vol. 9　No. 1　2014　Research paper (scientific journal)

Hypomagnesemia is a significant predictor of cardiovascular and non-cardiovascular mortality in patients undergoing hemodialysis.

Sakaguchi Y, Fujii N, Shoji T, Hayashi T, Rakugi H, Isaka Y, Kidney international

Kidney international　Vol. 85　No. 1　p. 174-181　2014/01

[Pneumonia in maintenance hemodialysis patients: detection rate of causative organisms in sputum varies with time of sampling and quality].

Sasaki K, Yamaguchi S, Iwahashi E, Fujimoto T, Minami S, Rakugi H, Isaka Y, Yokoyama K, Nihon Jinzo, Gakkai shi

Nihon Jinzo Gakkai shi　Vol. 56　No. 4　p. 524-531　2014

Magnesium modifies the cardiovascular mortality risk associated with hyperphosphatemia in patients undergoing hemodialysis: a cohort study.

Sakaguchi Y, Fujii N, Shoji T, Hayashi T, Rakugi H, Iseki K, Tsubakihara Y, Isaka Y, Committee of Renal, Data Registry of, the, Japanese, Society for Dialysis Therapy, PloS one

PloS one　Vol. 9　No. 12　2014

Performance of the Japanese glomerular filtration rate equation based on standardized serum cystatin C in potential kidney donors

Horio M, Yasuda Y, Kaimori J, Ichimaru N, Kakuta Y, Isaka Y, Matsuo S, Takahara S

Transplant Proc. 2014;46(2):314-7　Vol. 46　No. 2　p. 314-317　2014

Efficacy of continuous long-duration PMX-DHP for septic shock: propensity score analyses

Masaya Yamato, Hiromi Rakugi, Yoshitaka Isaka

CRITICAL CARE MEDICINE　Vol. 41　No. 12　2013/12　Research paper (scientific journal)

Age and prediction of remission and relapse of proteinuria and corticosteroid-related adverse events in adult-onset minimal-change disease: a retrospective cohort study.

Shinzawa M, Yamamoto R, Nagasawa Y, Oseto S, Mori D, Tomida K, Hayashi T, Izumi M, Fukunaga M, Yamauchi A, Tsubakihara Y, Rakugi H, Isaka Y, Clinical, experimental nephrology, v

Clinical and experimental nephrology　Vol. 17　No. 6　p. 839-847　2013/12　Research paper (scientific journal)

Fibroblast growth factor 23 and 25-hydroxyvitamin D levels are associated with estimated glomerular filtration rate decline.

Hamano T, Nakano C, Obi Y, Fujii N, Matsui I, Tomida K, Mikami S, Inoue K, Shimomura A, Kusunoki Y, Rakugi H, Isaka Y, Tsubakihara Y, Kidney international supplements

Kidney international supplements　Vol. 3　No. 5　p. 469-475　2013/12

Autophagy regulates cyclosporine-induced kindney injury thorugh alleviating metablic stress

KIMURA TOMONORI, TAKABATAKE YOSHITSUGU, ISAKA YOSHITAKA

Transplantation today　Vol. 26　No. 6　p. 497-499　2013/11　Research paper (scientific journal)

Autophagy protects kidney proximal tubule epithelial cells from mitochondrial metabolic stress.

Kimura T, Takahashi A, Takabatake Y, Namba T, Yamamoto T, Kaimori JY, Matsui I, Kitamura H, Niimura F, Matsusaka T, Soga T, Rakugi H, Isaka Y, Autophagy

Autophagy　Vol. 9　No. 11　p. 1876-1886　2013/11

心停止後ラット腎臓のfunctional MRIを用いた詳細な障害の評価と腎移植後グラフト予後予測可能性の検討

貝森淳哉, 岩井聡美, 小林英司, 畑中雅喜, 津田秀年, 小尾義嗣, 奥見雅由, 矢澤浩治, 市丸直嗣, 楽木宏美, 野々村祝夫, 猪阪善隆, 高原史郎

Organ Biol　Vol. 20　No. 3　p. 49-49　2013/10/20　Research paper (scientific journal)

糖尿病における降圧治療とその成績 (特集 糖尿病治療薬の最前線 : 臨床試験・臨床疫学的観点も含めて)

猪阪 善隆, 楽木 宏実

医薬ジャーナル　Vol. 49　No. 10　p. 119-130　2013/10　Research paper (scientific journal)

Rhabdomyolysis caused by peripheral T-cell lymphoma in skeletal muscle.

Sasaki K, Yamato M, Yasuda K, Rakugi H, Isaka Y, The American journal of, emergency medicine

The American journal of emergency medicine　Vol. 31　No. 10　p. 1537e3-5　2013/10

急性腎障害モデルにおける抗炎症性因子を介した同種他家卵膜由来間葉系幹細胞移植の腎保護作用

津田 秀年, 山原 研一, 大谷 健太郎, 斯波 真理子, 寒川 賢治, 高原 史郎, 猪阪 善隆

日本内分泌学会雑誌　Vol. 89　No. 2　p. 739-739　2013/09　Research paper (scientific journal)

Alu element再配列遺伝子異常による常染色体劣性Alport症候群の兄妹に対するそのhetero carrier両親からの生体腎移植

貝森 淳哉, 市丸 直嗣, 橋本 総子, Fu Xuejun, 橋村 裕也, 貝藤 裕史, 飯島 一誠, 畑中 雅喜, 高原 史郎, 楽木 宏実, 猪阪 善隆

日本臨床内科医会会誌　Vol. 28　No. 3　p. 428-428　2013/09　Research paper (scientific journal)

Association of nocturnal hypoxemia with progression of CKD.

Sakaguchi Y, Hatta T, Hayashi T, Shoji T, Suzuki A, Tomida K, Okada N, Rakugi H, Isaka Y, Tsubakihara Y, Clinical journal of, the American Society of Nephrology, CJASN, vo

Clinical journal of the American Society of Nephrology : CJASN　Vol. 8　No. 9　p. 1502-1507　2013/09

メタボロミクスの診断への応用と課題 キラルアミノ酸メタボロミクスによる疾患バイオマーカー探索への新しいアプローチ

浜瀬 健司, 三次 百合香, 笹部 潤平, 木村 友則, 山本 陵平, 三田 真史, 猪阪 善隆, 相磯 貞和

JSBMS Letters　Vol. 38　No. Suppl.　p. 35-35　2013/08

イメージング技術の移植への応用 移植腎臓live imaging:functional MRIとmultiphoton microscopy 2つのmodality

貝森 淳哉, 市丸 直嗣, 猪阪 善隆, 楽木 宏実, 石井 優, 小林 英司, 高原 史郎

移植　Vol. 48　No. 総会臨時　p. 239-239　2013/08　Research paper (scientific journal)

Autophagy sequesters damaged lysosomes to control lysosomal biogenesis and kidney injury.

Maejima I, Takahashi A, Omori H, Kimura T, Takabatake Y, Saitoh T, Yamamoto A, Hamasaki M, Noda T, Isaka Y, Yoshimori T

The EMBO journal　Vol. 32　No. 17　p. 2336-2347　2013/08　Research paper (scientific journal)

腹膜透析患者の血清リン値に外食・間食が及ぼす影響

岡本 千明, 新沢 真紀, 中野 智香子, 松本 稔子, 福辺 祥子, 寺西 順哉, 井上 和則, 北村 温美, 守山 敏樹, 猪阪 善隆

腎と透析　Vol. 75　No. 別冊 腹膜透析2013　p. 309-310　2013/07　Research paper (scientific journal)

Diuretic therapy and resistance from the point of renal physiology

Fluid management renaissance　Vol. 3　No. 3　p. 274-279　2013/07　Research paper (scientific journal)

Chronic Kidney Disease and Lifestyle Disease

ISAKA Yoshitaka

Vol. 61　No. 4　p. 209-213　2013/07/01　Research paper (scientific journal)

ASSOCIATION OF EXERCISE WITH PROTEINURIA IN A LARGE JAPANESE GENERAL POPULATION SAMPLE

Yasuyuki Nagasawa, Ryouhei Yamamoto, Maki Shinzawa, Yukiko Hasuike, Takahiro Kuragano, Hiromi Rakugi, Yoshitaka Isaka, Takeshi Nakanishi, Kunitoshi Iseki, Kunihiro Yamagata, Kazuhiko Tsuruya, Hideaki Yoshida, Shouichi Fujimoto, Koichi Asahi, Tsuyoshi Watanabe, Toshiki Moriyama

NEPHROLOGY DIALYSIS TRANSPLANTATION　Vol. 28　p. 143-144　2013/05　Research paper (scientific journal)

VITAMIN D STATUS PREDICTS REJECTION EPISODES AND CHANGE IN ALLOGRAFT KIDNEY FUNCTION OVER TIME IN KIDNEY TRANSPLANT RECIPIENTS

Obi Yoshitsugu, Hamano Takayuki, Ichimaru Naotsugu, Tomida Kodo, Fujii Naohiko, Matsui Isao, Kaimori Jun-ya, Rakugi Hiromi, Takahara Shiro, Isaka Yoshitaka, Tsubakihara Yoshiharu

NEPHROLOGY DIALYSIS TRANSPLANTATION　Vol. 28　p. 38-39　2013/05

Atypical hemolytic uremic syndrome with MCP mutations preceded by respiratory infection.

Yasuda K, Sasaki K, Yamato M, Rakugi H, Isaka Y, Hayashi T, Piras R, Bresin E

CEN case reports　Vol. 2　No. 1　p. 34-37　2013/05

Malt1-induced cleavage of regnase-1 in CD4(+) helper T cells regulates immune activation.

Uehata T, Iwasaki H, Vandenbon A, Matsushita K, Hernandez-Cuellar E, Kuniyoshi K, Satoh T, Mino T, Suzuki Y, Standley DM, Tsujimura T, Rakugi H, Isaka Y, Takeuchi O, Akira S, Cell

Cell　Vol. 153　No. 5　p. 1036-1049　2013/05　Research paper (scientific journal)

Renal transplantations from parents to siblings with autosomal recessive Alport syndrome caused by a rearrangement in an intronic antisense Alu element in the COL4A3 gene led to different outcomes.

Kaimori JY, Ichimaru N, Isaka Y, Hashimoto F, Fu X, Hashimura Y, Kaito H, Iijima K, Kyo M, Namba T, Obi Y, Hatanaka M, Matsui I, Takabatake Y, Okumi M, Yazawa K, Nonomura N, Rakugi H, Takahara S

CEN case reports　Vol. 2　No. 1　p. 98-101　2013/05　Research paper (scientific journal)

特定健診コホートにおける、運動習慣の尿蛋白陽性化への影響の検討

長澤 康行, 山本 陵平, 新沢 真紀, 蓮池 由起子, 倉賀野 隆裕, 楽木 宏実, 猪阪 善隆, 中西 健, 井関 邦敏, 山縣 邦弘, 鶴屋 和彦, 吉田 英昭, 藤元 昭一, 旭 浩一, 渡辺 毅, 守山 敏樹, 厚生労働科学研究費補助金「今後の特定健康診査・保健指導における慢性腎臓病(CKD)の位置付けに関する検討」

日本腎臓学会誌　Vol. 55　No. 3　p. 327-327　2013/04

成人発症の微小変化型ネフローゼ症において、高齢者は有意に寛解が遅く再発は少ない

新沢 真紀, 山本 陵平, 長澤 康行, 大瀬戸 奨, 森 大輔, 冨田 弘道, 林 晃正, 和泉 雅章, 福永 恵, 山内 淳, 椿原 美治, 楽木 宏実, 猪阪 善隆

日本腎臓学会誌　Vol. 55　No. 3　p. 401-401　2013/04　Research paper (scientific journal)

A single daily dose enhances the adherence to immunosuppressive treatment in kidney transplant recipients: a cross-sectional study.

Obi Y, Ichimaru N, Kato T, Kaimori JY, Okumi M, Yazawa K, Rakugi H, Nonomura N, Isaka Y, Takahara S, Clinical, experimental nephrology, v

Clinical and experimental nephrology　Vol. 17　No. 2　p. 310-315　2013/04　Research paper (scientific journal)

Prognostic significance of left ventricular hypertrophy observed at dialysis initiation depends on the pre-dialysis use of erythropoiesis-stimulating agents.

Hayashi T, Kimura T, Yasuda K, Obi Y, Sasaki K, Iio K, Miyasato K, Kamimura T, Kitamura H, Tsubakihara Y, Rakugi H, Isaka Y, Clinical, experimental nephrology, v

Clinical and experimental nephrology　Vol. 17　No. 2　p. 294-303　2013/04

Retention of fetuin-A in renal tubular lumen protects the kidney from nephrocalcinosis in rats.

Isao Matsui, Takayuki Hamano, Satoshi Mikami, Kazunori Inoue, Akihiro Shimomura, Yasuyuki Nagasawa, Toshimi Michigami, Tomokazu Ohnishi, Naohiko Fujii, Chikako Nakano, Yasuo Kusunoki, Harumi Kitamura, Hirotsugu Iwatani, Yoshitsugu Takabatake, Jun-ya Kaimori, Go Matsuba, Kento Okoshi, Hiromi Kimura-Suda, Yoshiharu Tsubakihara, Hiromi Rakugi, Yoshitaka Isaka

American journal of physiology. Renal physiology　Vol. 304　No. 6　2013/03/15　Research paper (scientific journal)

Retention of fetuin-A in renal tubular lumen protects the kidney from nephrocalcinosis in rats.

Matsui I, Hamano T, Mikami S, Inoue K, Shimomura A, Nagasawa Y, Michigami T, Ohnishi T, Fujii N, Nakano C, Kusunoki Y, Kitamura H, Iwatani H, Takabatake Y, Kaimori JY, Matsuba G, Okoshi K, Kimura-Suda H, Tsubakihara Y, Rakugi H, Isaka Y

Am J Physiol Renal Physiol.　2013/03　Research paper (scientific journal)

Clinical nephrology 尿細管・間質障害 オートファジー不全による尿細管障害

猪阪 善隆, 木村 友則, 高畠 義嗣

Annual Review腎臓　Vol. 2013　p. 234-240　2013/01　Research paper (scientific journal)

The role of cyclic-AMP in the steroid-induced tissue fibrosis and thrombus formation

Vol. 10　No. 1　p. 7-13　2013　Research paper (scientific journal)

高齢者CKD合併高血圧の降圧目標値は (特集 CKD合併高血圧のコントロバーシー : 今,明らかにされるべきこと)

猪阪 善隆, 楽木 宏実

腎・高血圧の最新治療 = Current topics of kidney and hypertension : 腎・高血圧治療の今を伝える専門誌　Vol. 2　No. 4　p. 208-213　2013　Research paper (scientific journal)

Non-myeloablative conditioning is sufficient to induce mixed chimerism and subsequent acceptance of donor specific cardiac and skin grafts

Chi Liu, Ping Zhu, Taro Saito, Yoshitaka Isaka, Yukitoshi Nagahara, Jian Zhuang, Xiao-Kang Li

International Immunopharmacology　Vol. 16　No. 3　p. 392-398　2013　Research paper (scientific journal)

Chloroquine in cancer therapy: a double-edged sword of autophagy.

Kimura T, Takabatake Y, Takahashi A, Isaka Y

Cancer research　Vol. 73　No. 1　p. 3-7　2013/01

[Management of CKD-MBD in kidney transplant patients].

Isaka Y, Fujii N, Rakugi H, Nihon Jinzo, Gakkai shi

Nihon Jinzo Gakkai shi　Vol. 55　No. 2　p. 153-158　2013

Non-invasive magnetic resonance imaging in rats for prediction of the fate of grafted kidneys from cardiac death donors.

Kaimori JY, Iwai S, Hatanaka M, Teratani T, Obi Y, Tsuda H, Isaka Y, Yokawa T, Kuroda K, Ichimaru N, Okumi M, Yazawa K, Rakugi H, Nonomura N, Takahara S, Kobayashi E, PloS one

PloS one　Vol. 8　No. 5　2013　Research paper (scientific journal)

A nonerythropoietic derivative of erythropoietin inhibits tubulointerstitial fibrosis in remnant kidney.

Imamura R, Isaka Y, Sandoval RM, Ichimaru N, Abe T, Okumi M, Yazawa K, Kitamura H, Kaimori J, Nonomura N, Rakugi H, Molitoris BA, Takahara S, Clinical, experimental nephrology, v

Clinical and experimental nephrology　Vol. 16　No. 6　p. 852-862　2012/12　Research paper (scientific journal)

Serum hepcidin-25 levels predict the progression of renal anemia in patients with non-dialysis chronic kidney disease.

Niihata K, Tomosugi N, Uehata T, Shoji T, Mitsumoto K, Shimizu M, Kawabata H, Sakaguchi Y, Suzuki A, Hayashi T, Okada N, Isaka Y, Rakugi H, Tsubakihara Y, Nephrology, dialysis, transplantation, official publication of, the, European Dialysis, Transplant Association, European Renal Association, discussion

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association　Vol. 27　No. 12　p. 4378-85; discussion 4384　2012/12

Maxacalcitol ameliorates tubulointerstitial fibrosis in obstructed kidneys by recruiting PPM1A/VDR complex to pSmad3.

Inoue K, Matsui I, Hamano T, Fujii N, Shimomura A, Nakano C, Kusunoki Y, Takabatake Y, Hirata M, Nishiyama A, Tsubakihara Y, Isaka Y, Rakugi H, Laboratory investigation, a journal of technical methods, pathology, vo

Laboratory investigation; a journal of technical methods and pathology　Vol. 92　No. 12　p. 1686-1697　2012/12

Anti-1-Adrenergic Receptor Autoantibody is an Independent Predictor of All Cause Mortality in Dialysis Patients

Masaya Yamato, Keiko Yasuda, Koichi Sasaki, Terumasa Hayashi, Hiromi Rakugi, Yoshitaka Isaka

CIRCULATION　Vol. 126　No. 21　2012/11　Research paper (scientific journal)

予後影響因子としてのCKD-MBD 保存期の血清FGF23値と、透析導入および透析導入前後でのCVDイベントとの関連

中野 智香子, 濱野 高行, 松井 功, 猪阪 善隆

日本透析医学会雑誌　Vol. 45　No. 11　p. 1001-1003　2012/11

Quantitative change of IgA hinge O-glycan composition is a novel marker of therapeutic responses of IgA nephropathy.

Iwatani H, Inoue T, Wada Y, Nagasawa Y, Yamamoto R, Iijima H, Takehara T, Imai E, Rakugi H, Isaka Y, Biochemical, biophysical research communications

Biochemical and biophysical research communications　Vol. 428　No. 3　p. 339-342　2012/11　Research paper (scientific journal)

残腎機能のある腹膜透析患者ではCinacalcetによる血清リン値の低下は期待できない

小尾 佳嗣, 濱野 高行, 北村 温美, 椿原 美治, 中野 智香子, 新澤 真紀, 岩谷 博次, 楽木 宏実, 猪阪 善隆

腎と骨代謝　Vol. 25　No. 4　p. 348-349　2012/10　Research paper (scientific journal)

当院における成人発症微小変化型ネフローゼ症候群の臨床的特徴

森 大輔, 新沢 真紀, 難波 倫子, 山口 嘉士, 板野 精之, 今北 菜津子, 松田 潤, 村田 尚子, 竹治 正展, 山本 陵平, 猪阪 善隆, 山内 淳

日本腎臓学会誌　Vol. 54　No. 7　p. 1023-1030　2012/10　Research paper (scientific journal)

心停止後ラット腎臓のfunctional MRIを用いた詳細な障害の検討

貝森 淳哉, 岩井 聡美, 小林 英司, 畑中 雅喜, 津田 秀年, 小尾 義嗣, 奥見 雅由, 矢澤 浩治, 市丸 直嗣, 楽木 宏美, 野々村 祝夫, 猪阪 善隆, 高原 史郎

Organ Biology　Vol. 19　No. 2　p. 222-222　2012/10　Research paper (scientific journal)

Orally active vitamin d for potential chemoprevention of posttransplant malignancy.

Obi Y, Ichimaru N, Hamano T, Tomida K, Matsui I, Fujii N, Okumi M, Kaimori JY, Yazawa K, Kokado Y, Tsubakihara Y, Nonomura N, Rakugi H, Takahara S, Isaka Y, Cancer prevention research, Philadelphia, Pa.), vo

Cancer prevention research (Philadelphia, Pa.)　Vol. 5　No. 10　p. 1229-1235　2012/10　Research paper (scientific journal)

Dialysis vintage and parathyroid hormone level, not fibroblast growth factor-23, determines chronic-phase phosphate wasting after renal transplantation.

Tomida K, Hamano T, Ichimaru N, Fujii N, Matsui I, Nonomura N, Tsubakihara Y, Rakugi H, Takahara S, Isaka Y, Bone, v

Bone　Vol. 51　No. 4　p. 729-736　2012/10　Research paper (scientific journal)

Febuxostat suppressed renal ischemia-reperfusion injury via reduced oxidative stress.

Tsuda H, Kawada N, Kaimori JY, Kitamura H, Moriyama T, Rakugi H, Takahara S, Isaka Y, Biochemical, biophysical research communications

Biochemical and biophysical research communications　Vol. 427　No. 2　p. 266-272　2012/10

Plasma B-type natriuretic peptide level predicts kidney prognosis in patients with predialysis chronic kidney disease.

Yasuda K, Kimura T, Sasaki K, Obi Y, Iio K, Yamato M, Rakugi H, Isaka Y, Hayashi T, Nephrology, dialysis, transplantation, official publication of, the, European Dialysis, Transplant Association, European Renal Association

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association　Vol. 27　No. 10　p. 3885-3891　2012/10

Deficiency of N-acetylgalactosamine in O-linked oligosaccharides of IgA is a novel biologic marker for Crohn's disease

Takahiro Inoue, Hideki Iijima, Michiko Tajiri, Shinichiro Shinzaki, Eri Shiraishi, Satoshi Hiyama, Akira Mukai, Sachiko Nakajima, Hirotsugu Iwatani, Tsutomu Nishida, Tsunekazu Mizushima, Teruhito Yasui, Yoshitaka Isaka, Tatsuya Kanto, Masahiko Tsujii, Eiji Miyoshi, Yoshinao Wada, Tetsuo Takehara

INFLAMMATORY BOWEL DISEASES　Vol. 18　No. 9　p. 1723-1734　2012/09　Research paper (scientific journal)

Use of xanthine oxidase inhibitor febuxostat inhibits renal interstitial inflammation and fibrosis in unilateral ureteral obstructive nephropathy.

Omori H, Kawada N, Inoue K, Ueda Y, Yamamoto R, Matsui I, Kaimori J, Takabatake Y, Moriyama T, Isaka Y, Rakugi H, Clinical, experimental nephrology, v

Clinical and experimental nephrology　Vol. 16　No. 4　p. 549-556　2012/08

Implausible similarities in patient characteristics between two randomized controlled studies: a coincidence is unlikely

Yoshitsugu Obi, Hitomi Hama, Yoshiki Suzuki, Yoshitaka Isaka, Toshiki Moriyama

KIDNEY INTERNATIONAL　Vol. 82　No. 1　p. 115-116　2012/07　Research paper (scientific journal)

Hypomagnesemia in type 2 diabetic nephropathy: a novel predictor of end-stage renal disease.

Sakaguchi Y, Shoji T, Hayashi T, Suzuki A, Shimizu M, Mitsumoto K, Kawabata H, Niihata K, Okada N, Isaka Y, Rakugi H, Tsubakihara Y, Diabetes care

Diabetes care　Vol. 35　No. 7　p. 1591-1597　2012/07

Hydrogen-rich University of Wisconsin solution attenuates renal cold ischemia-reperfusion injury.

Abe T, Li XK, Yazawa K, Hatayama N, Xie L, Sato B, Kakuta Y, Tsutahara K, Okumi M, Tsuda H, Kaimori JY, Isaka Y, Natori M, Takahara S, Nonomura N

Transplantation　Vol. 94　No. 1　p. 14-21　2012/07　Research paper (scientific journal)

Performance of the Japanese GFR equation in potential kidney donors.

Horio M, Yasuda Y, Kaimori J, Ichimaru N, Isaka Y, Takahara S, Nishi S, Uchida K, Takeda A, Hattori R, Kitada H, Tsuruya K, Imai E, Takahashi K, Watanabe T, Matsuo S

Clinical and experimental nephrology　Vol. 16　No. 3　p. 415-420　2012/06　Research paper (scientific journal)

Intact fibroblast growth factor 23 levels predict incident cardiovascular event before but not after the start of dialysis.

Nakano C, Hamano T, Fujii N, Obi Y, Matsui I, Tomida K, Mikami S, Inoue K, Shimomura A, Nagasawa Y, Okada N, Tsubakihara Y, Rakugi H, Isaka Y, Bone, v

Bone　Vol. 50　No. 6　p. 1266-1274　2012/06

ASSOCIATION BETWEEN LIVER ENZYMES AND PROTEINURIA STRATIFIED ON DRINKING STATUS: A NATIONWIDE CROSS-SECTIONAL STUDY

Toshihiro Ishigami, Toshihiro Ishigami, Ryohei Yamamoto, Yasuyuki Nagasawa, Yoshitaka Isaka, Tsuneo Konta, Kunitoshi Iseki, Toshiki Moriyama, Kunihiro Yamagata, Kazuhiko Tsuruya, Hideaki Yoshida, Shouichi Fujimoto, Koichi Asahi, Tsuyoshi Watanabe

NEPHROLOGY DIALYSIS TRANSPLANTATION　Vol. 27　p. 125-126　2012/05　Research paper (scientific journal)

METHYLPREDNISOLONE PULSE THERAPY ACCELERATED COMPLETE REMISSION OF PROTEINURIA IN ADULT-ONSET MINIMAL CHANGE NEPHROTIC SYNDROME PATIENTS

Maki Shinzawa, Ryohei Yamamoto, Yasuyuki Nagasawa, Susumu Oseto, Daisuke Mori, Kakuya Niihata, Megumu Fukunaga, Atsushi Yamauchi, Yoshiharu Tsubakihara, Hiromi Rakugi, Yoshitaka Isaka

NEPHROLOGY DIALYSIS TRANSPLANTATION　Vol. 27　p. 421-422　2012/05　Research paper (scientific journal)

ACE INSERTION(I)/DELETION(D) POLYMORPHISM PREDICTED RENOPROTECTIVE EFFECTIVENESS OF RENIN-ANGIOTENSIN SYSTEM (RAS) BLOCKADE IN PATIENTS WITH IGA NEPHROPATHY

Junya Teranishi, Ryohei Yamamoto, Yasuyuki Nagasawa, Tatsuya Shoji, Hirotsugu Iwatani, Noriyuki Okada, Toshiki Moriyama, Atsushi Yamauchi, Yoshiharu Tsubakihara, Enyu Imai, Hiromi Rakugi, Yoshitaka Isaka

NEPHROLOGY DIALYSIS TRANSPLANTATION　Vol. 27　p. 188-188　2012/05　Research paper (scientific journal)

OSTEOPROTEGERIN REPLACES CORONARY ARTERY CALCIFICATION SCORE AS A PREDICTOR OF INCIDENT CARDIOVASCULAR EVENTS IN DIABETIC CHRONIC KIDNEY DISEASE

Chikako Nakano, Chikako Nakano, Takayuki Hamano, Naohiko Fujii, Yoshitsugu Obi, Isao Matsui, Satoshi Mikami, Kazunori Inoue, Akihiro Shimomura, Hiromi Rakugi, Yoshitaka Isaka

NEPHROLOGY DIALYSIS TRANSPLANTATION　Vol. 27　p. 127-128　2012/05　Research paper (scientific journal)

BONE TURNOVER MARKERS ASSOCIATE MORE STRONGLY WITH CARDIOVASCULAR MORTALITY THAN ALL-CAUSE DEATH IN MAINTENANCE HEMODIALYSIS PATIENTS

Naohiko Fujii, Takayuki Hamano, Chikako Nakano, Sayoko Yonemoto, Ayako Okuno, Masaya Katayama, Yoshitaka Isaka

NEPHROLOGY DIALYSIS TRANSPLANTATION　Vol. 27　p. 293-293　2012/05　Research paper (scientific journal)

THE EFFECT OF INDOXYL SULFATE ON INTESTINAL IMMUNOLOGY IN CHRONIC KIDNEY DISEASE

Yoshiyasu Ueda, Hirotsugu Iwatani, Yoshitaka Isaka

NEPHROLOGY DIALYSIS TRANSPLANTATION　Vol. 27　p. 444-444　2012/05　Research paper (scientific journal)

INTACT FIBROBLAST GROWTH FACTOR 23 LEVELS PREDICT INCIDENT CARDIOVASCULAR EVENT BEFORE BUT NOT AFTER THE START OF DIALYSIS

Sayoko Yonemoto, Takayuki Hamano, Naohiko Fujii, Yoshitugu Obi, Isao Matsui, Satoshi Mikami, Chikako Nakano, Kazunori Inoue, Akihiro Shimomura, Noriyuki Okada, Yoshiharu Tsubakihara, Hiromi Rakugi, Yoshitaka Isaka, Masaya Katayama

NEPHROLOGY DIALYSIS TRANSPLANTATION　Vol. 27　p. 19-20　2012/05　Research paper (scientific journal)

NOVEL XANTHINE OXIDOREDUCTASE INHIBITOR, FEBUXOSTAT, ATTENUATES RENAL ISCHEMIA-REPERFUSION INJURY IN RATS

Hidetoshi Tsuda, Noritaka Kawada, Hirotsugu Iwatani, Toshiki Moriyama, Shiro Takahara, Hiromi Rakugi, Yoshitaka Isaka

NEPHROLOGY DIALYSIS TRANSPLANTATION　Vol. 27　p. 339-339　2012/05　Research paper (scientific journal)

FIBROBLAST GROWTH FACTOR 23 AND 25-HYDROXYVITAMIN D PREDICT ANNUALIZED ESTIMATED GFR DECLINE

Takayuki Hamano, Chikako Nakano, Naohiko Fujii, Yoshitugu Obi, Satoshi Mikami, Kazunori Inoue, Isao Matsui, Noriyuki Okada, Yoshiharu Tsubakihara, Yoshitaka Isaka, Hiromi Rakugi

NEPHROLOGY DIALYSIS TRANSPLANTATION　Vol. 27　p. 104-104　2012/05　Research paper (scientific journal)

Multi-Photon Microscopy Based Kidney Live Imaging Identifies a Series of Micro-Circulation Changes in a Rat Acute Kidney Rejection Model

J. Y. Kaimori, T. Abe, H. Tsuda, M. Ishii, M. Okumi, K. Yazawa, Y. Isaka, H. Rakugi, N. Nonomura, S. Takahara

AMERICAN JOURNAL OF TRANSPLANTATION　Vol. 12　p. 30-30　2012/05　Research paper (scientific journal)

USE OF XANTHINE OXIDASE INHIBITOR FEBUXOSTAT INHIBITS RENAL INTERSTITIAL INFLAMMATION AND FIBROSIS IN UNILATERAL URETERAL OBSTRUCTIVE NEPHROPATHY

Hiroki Omori, Noritaka Kawada, Kazunori Inoue, Yoshiyasu Ueda, Ryohei Yamamoto, Isao Matsui, Jyunya Kaimori, Yoshitsugu Takabatake, Toshiki Moriyama, Yoshitaka Isaka, Hiromi Rakugi

NEPHROLOGY DIALYSIS TRANSPLANTATION　Vol. 27　p. 431-431　2012/05　Research paper (scientific journal)

THE IMPACT OF ONCE-DAILY DOSING ON ADHERENCE TO IMMUNOSUPPRESSIVE MEDICATION IN KIDNEY TRANSPLANT RECIPIENTS

Obi Yoshitsugu, Ichimaru Naotsugu, Kato Taigo, Okumi Masayoshi, Kaimori Junya, Yazawa Koji, Nonomura Norio, Isaka Yoshitaka, Takahara Shiro

NEPHROLOGY DIALYSIS TRANSPLANTATION　Vol. 27　2012/05

CKDと脳心血管疾患との密接な関連を読み解く・・・血管石灰化の関与

松井 功, 濱野 高行, 猪阪 善隆, 楽木 宏実

2012/05

Combined use of vitamin D status and FGF23 for risk stratification of renal outcome.

Nakano C, Hamano T, Fujii N, Matsui I, Tomida K, Mikami S, Inoue K, Obi Y, Okada N, Tsubakihara Y, Isaka Y, Rakugi H, Clinical journal of, the American Society of Nephrology, CJASN, vo

Clinical journal of the American Society of Nephrology : CJASN　Vol. 7　No. 5　p. 810-819　2012/05

Gene Therapy Targeting Kidney Diseases: Routes and Vehicles

Yoshitaka Isaka, Yoshitsugu Takabatake, Hiromi Rakugi

Antibody-Mediated Drug Delivery Systems: Concepts, Technology, and Applications　p. 267-277　2012/04/23　Part of collection (book)

オルガネラと腎障害の密接な関係を紐解く 腎疾患に対抗する防御機構としてのオートファジー

高畠 義嗣, 木村 友則, 猪阪 善隆, 楽木 宏実

日本腎臓学会誌　Vol. 54　No. 3　p. 197-197　2012/04　Research paper (scientific journal)

オートファジーはシスプラチンによる急性腎障害の進行を防御する

高橋 篤史, 木村 友則, 高畠 義嗣, 難波 倫子, 山本 毅士, 北村 温美, 松阪 泰二, 新村 文男, 楽木 宏実, 猪阪 善隆

日本腎臓学会誌　Vol. 54　No. 3　p. 228-228　2012/04　Research paper (scientific journal)

新規Xanthine oxidase阻害剤 Febuxostatは一側尿管結紮モデルでの腎尿細管間質の炎症と線維化を抑制する

大森 弘基, 川田 典孝, 守山 敏樹, 上田 仁康, 木村 友則, 畑中 雅喜, 堀尾 勝, 高原 史郎, 楽木 宏実, 猪阪 善隆

日本腎臓学会誌　Vol. 54　No. 3　p. 238-238　2012/04　Research paper (scientific journal)

ACEi/ARB内服中の慢性腎臓病または高血圧症例への、エプレレノン追加投与の心保護作用について

川田 典孝, 守山 敏樹, 木村 友則, 高橋 篤史, 北村 温美, 貝森 淳哉, 高畠 義嗣, 堀尾 勝, 楽木 宏実, 猪阪 善隆

日本腎臓学会誌　Vol. 54　No. 3　p. 265-265　2012/04　Research paper (scientific journal)

ACEi/ARB内服CKD症例への、抗アルドステロン薬 エプレレノン追加投与の心保護作用について

北村 温美, 川田 典孝, 守山 敏樹, 木村 友則, 高橋 篤史, 貝森 淳哉, 高畠 義嗣, 堀尾 勝, 楽木 宏実, 猪阪 善隆

日本高血圧学会臨床高血圧フォーラムプログラム・抄録集　Vol. 1回　p. 154-154　2012/04

腎虚血再灌流障害における卵膜由来間葉系幹細胞の抗炎症作用の機序検討

津田 秀年, 山原 研一, 奥見 雅由, 矢澤 浩治, 貝森 淳哉, 猪阪 善隆, 池田 智明, 高原 史郎

日本腎臓学会誌　Vol. 54　No. 3　p. 268-268　2012/04

腎糸球体IgA沈着にはTLR9刺激ではなく、微生物学的環境が関与する

岩谷 博次, 長澤 康行, 上田 仁康, 山本 陵平, 新澤 真紀, 大西 智和, 松口 徹也, 楽木 宏実, 猪阪 善隆

日本腎臓学会誌　Vol. 54　No. 3　p. 243-243　2012/04　Research paper (scientific journal)

Gene polymorphisms contributing to hypertension in immunoglobulin A nephropathy.

Shinzawa M, Yamamoto R, Nagasawa Y, Shoji T, Obi Y, Namba T, Kitamura H, Kaneko T, Okada N, Iwatani H, Yamauchi A, Tsubakihara Y, Imai E, Isaka Y, Rakugi H, Clinical, experimental nephrology, v

Clinical and experimental nephrology　Vol. 16　No. 2　p. 250-258　2012/04

Autophagy and kidney aging

TAKABATAKE Yoshitsugu, KIMURA Tomonori, ISAKA Yoshitaka

The Japanese journal of nephrology　Vol. 54　No. 2　p. 78-85　2012/03/25　Research paper (scientific journal)

HIV関連腎症によりネフローゼ症候群と急速な腎機能低下をきたした1例

木村 友則, 安田 圭子, 小尾 佳嗣, 佐藤 壽浩, 難波 倫子, 佐々木 公一, 村本 記子, 和田 晃, 楽木 宏美, 猪阪 善隆, 林 晃正

日本腎臓学会誌　Vol. 54　No. 2　p. 94-98　2012/03　Research paper (scientific journal)

Serum hepcidin-25 levels and anemia in non-dialysis chronic kidney disease patients: a cross-sectional study.

Uehata T, Tomosugi N, Shoji T, Sakaguchi Y, Suzuki A, Kaneko T, Okada N, Yamamoto R, Nagasawa Y, Kato K, Isaka Y, Rakugi H, Tsubakihara Y, Nephrology, dialysis, transplantation, official publication of, the, European Dialysis, Transplant Association, European Renal Association

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association　Vol. 27　No. 3　p. 1076-1083　2012/03

A candidate gene approach to genetic contributors to the development of IgA nephropathy.

Yamamoto R, Nagasawa Y, Shoji T, Katakami N, Ohtoshi K, Hayaishi-Okano R, Yamasaki Y, Yamauchi A, Tsubakihara Y, Imai E, Rakugi H, Isaka Y, Nephrology, dialysis, transplantation, official publication of, the, European Dialysis, Transplant Association, European Renal Association

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association　Vol. 27　No. 3　p. 1020-1030　2012/03

Self-reported sleep duration and prediction of proteinuria: a retrospective cohort study.

Yamamoto R, Nagasawa Y, Iwatani H, Shinzawa M, Obi Y, Teranishi J, Ishigami T, Yamauchi-Takihara K, Nishida M, Rakugi H, Isaka Y, Moriyama T, American journal, of, kidney diseases, the official journal of, the National, Kidney Foundation

American journal of kidney diseases : the official journal of the National Kidney Foundation　Vol. 59　No. 3　p. 343-355　2012/03

Cigarette smoking and chronic kidney diseases.

Nagasawa Y, Yamamoto R, Rakugi H, Isaka Y, Hypertension research, official journal of, the, Japanese, Society of Hyper, ension

Hypertension research : official journal of the Japanese Society of Hypertension　Vol. 35　No. 3　p. 261-265　2012/03

Deficiency of claudin-18 causes paracellular H+ leakage, up-regulation of interleukin-1β, and atrophic gastritis in mice.

Daisuke Hayashi, Atsushi Tamura, Hiroo Tanaka, Yuji Yamazaki, Shin Watanabe, Koya Suzuki, Kazuo Suzuki, Kazuhiro Sentani, Wataru Yasui, Hiromi Rakugi, Yoshitaka Isaka, Sachiko Tsukita

Gastroenterology　Vol. 142　No. 2　p. 292-304　2012/02　Research paper (scientific journal)

Towards developing new strategies to reduce the adverse side-effects of nonsteroidal anti-inflammatory drugs.

Kawada N, Moriyama T, Kitamura H, Yamamoto R, Furumatsu Y, Matsui I, Takabatake Y, Nagasawa Y, Imai E, Wilcox CS, Rakugi H, Isaka Y, Clinical, experimental nephrology, v

Clinical and experimental nephrology　Vol. 16　No. 1　p. 25-29　2012/02

Autophagy guards against cisplatin-induced acute kidney injury.

Takahashi A, Kimura T, Takabatake Y, Namba T, Kaimori J, Kitamura H, Matsui I, Niimura F, Matsusaka T, Fujita N, Yoshimori T, Isaka Y, Rakugi H, The American journal of, a, h

The American journal of pathology　Vol. 180　No. 2　p. 517-525　2012/02　Research paper (scientific journal)

腎機能障害合併高血圧症に対する降圧薬選択 (特集 腎性高血圧と動脈硬化)

猪阪 善隆, 楽木 宏実

腎・高血圧の最新治療 = Current topics of kidney and hypertension : 腎・高血圧治療の今を伝える専門誌　Vol. 1　No. 1　p. 20-25　2012　Research paper (scientific journal)

Enhanced tumor immunity of WT1 peptide vaccination by interferon-beta administration

Hiroko Nakajima, Yoshihiro Oka, Akihiro Tsuboi, Naoya Tatsumi, Yumiko Yamamoto, Fumihiro Fujiki, Zheyu Li, Ayako Murao, Soyoko Morimoto, Naoki Hosen, Toshiaki Shirakata, Sumiyuki Nishida, Ichiro Kawase, Yoshitaka Isaka, Yusuke Oji, Haruo Sugiyama

VACCINE　Vol. 30　No. 4　p. 722-729　2012/01　Research paper (scientific journal)

[Clinical characteristics of adult-onset minimal change nephrotic syndrome in our hospital].

Mori D, Shinzawa M, Namba T, Yamaguchi Y, Itano S, Imakita N, Matsuda J, Murata H, Takeji M, Yamamoto R, Isaka Y, Yamauchi A

Nihon Jinzo Gakkai shi　Vol. 54　No. 7　p. 1023-1030　2012　Research paper (scientific journal)

腎移植待機中に一過性に著明な心機能低下を来たした一例

石見成史, 上田宏達, 岩花東吾, 岡田健志, 谷口達典, 横山光樹, 市堀泰裕, 神崎万智子, 溝手勇, 大谷朋仁, 朝野仁裕, 坂田泰史, 南都伸介, 小室一成, 畑中雅喜, 猪阪善隆

日本循環器学会近畿地方会(Web)　Vol. 113th　2012

A case of nephrocalcinosis associated with primary aldosteronism.

Yasuda K, Sasaki K, Yamato M, Rakugi H, Isaka Y, Hayashi T, Internal medicine, Tokyo, Ja

Internal medicine (Tokyo, Japan)　Vol. 51　No. 6　p. 625-627　2012

[Case of HIV-associated nephropathy accompanied by nephrotic syndrome and acute worsening of kidney function].

Kimura T, Yasuda K, Obi Y, Satoh T, Namba T, Sasaki K, Muramoto N, Wada A, Rakugi H, Isaka Y, Hayashi T, Nihon Jinzo, Gakkai shi

Nihon Jinzo Gakkai shi　Vol. 54　No. 2　p. 94-98　2012

Reply to "FGF23 adds value to risk prediction in patients with chronic kidney disease"

Hamano T, Nakano C, Fujii N, Matsui I, Tomida K, Mikami S, Inoue K, Obi Y, Shimomura A, Okada N, Rakugi H, Isaka Y, Tsubakihara Y

Bone　Vol. 51　No. 4　p. 832-833　2012

Implication of autophagy in response to tubular ageing and injuries

Isaka Y, Kimura T, Takabatake Y, Rakugi H

Autophagy: Principles, Regulation and Roles in Disease　p. 329-340　2012

Carbamylated erythropoietin ameliorates cyclosporine nephropathy without stimulating erythropoiesis.

Abe T, Isaka Y, Imamura R, Kakuta Y, Okumi M, Yazawa K, Ichimaru N, Tsuda H, Nonomura N, Takahara S, Okuyama A

Cell transplantation　Vol. 21　No. 2-3　p. 571-580　2012　Research paper (scientific journal)

LDLアフェレシスとステロイド療法の併用が有効であったコレステロール結晶塞栓症の1例

安田 圭子, 佐々木 公一, 倭 正也, 川上 遊貴, 大畑 達哉, 三代 千恵, 岩本 匡史, 渕脇 栄治, 楽木 宏実, 猪阪 善隆, 林 晃正

日本透析医学会雑誌　Vol. 44　No. 12　p. 1185-1191　2011/12　Research paper (scientific journal)

Tubulointerstitial nephritis and uveitis syndrome with transient hyperthyroidism in an elderly patient.

Yasuda K, Sasaki K, Yamato M, Rakugi H, Isaka Y, Hayashi T, Clinical, experimental nephrology, v

Clinical and experimental nephrology　Vol. 15　No. 6　p. 927-932　2011/12

Safety and efficacy of administering the maximal dose of candesartan in renal transplant recipients.

Okumi M, Kawada N, Ichimaru N, Kitamura H, Abe T, Imamura R, Kojima Y, Kokado Y, Isaka Y, Rakugi H, Nonomura N, Moriyama T, Takahara S, Clinical, experimental nephrology, v

Clinical and experimental nephrology　Vol. 15　No. 6　p. 907-915　2011/12　Research paper (scientific journal)

Effects of nicorandil on the reduction of BNP levels in patients with chronic kidney disease.

Kimura T, Kitamura H, Inoue K, Kawada N, Matsui I, Nagasawa Y, Obi Y, Shinzawa M, Sakata Y, Hamono T, Rakugi H, Isaka Y, Clinical, experimental nephrology, v

Clinical and experimental nephrology　Vol. 15　No. 6　p. 854-860　2011/12

活性型ビタミンDが腎移植患者の拒絶反応を減少させる可能性

小尾 佳嗣, 冨田 弘道, 藤井 直彦, 濱野 高行, 市丸 直嗣, 貝森 淳也, 高原 史郎, 奥見 雅由, 矢澤 浩治, 京 昌弘, 小角 幸人, 楽木 宏美, 猪阪 善隆

腎と骨代謝　Vol. 24　No. 4　p. 315-315　2011/10　Research paper (scientific journal)

Claudin-18の欠損はマウスのparacellar proton leak、IL-1の上昇、萎縮性胃炎を引き起こす(Deficiency of Claudin-18 cause paracellular proton leak,up-regulation IL-1and atrophic gastritis in mice)

林 大祐, 田村 淳, 田中 啓雄, 山崎 裕自, 渡辺 慎, 鈴木 浩也, 鈴木 和男, 仙谷 和弘, 安井 弥, 猪阪 善隆, 楽木 宏実, 月田 早智子

日本生化学会大会プログラム・講演要旨集　Vol. 84回　p. 3P-0565　2011/09

The protective role of autophagy against aging and acute ischemic injury in kidney proximal tubular cells

Yoshitaka Isaka, Tomonori Kimura, Yoshitsugu Takabatake

AUTOPHAGY　Vol. 7　No. 9　p. 1085-1087　2011/09

非定型抗酸菌による出口部およびカフ部の感染を来たし、腹膜透析療法を離脱した一例

早川 友朗, 寺西 順哉, 下村 明弘, 難波 倫子, 新沢 真紀, 北村 温美, 松井 功, 長澤 康行, 猪阪 善隆

日本腎臓学会誌　Vol. 53　No. 6　p. 825-825　2011/08　Research paper (scientific journal)

Effects of chronic kidney disease and post-angiographic acute kidney injury on long-term prognosis after coronary artery angiography.

Kimura T, Obi Y, Yasuda K, Sasaki K, Takeda Y, Nagai Y, Imai E, Rakugi H, Isaka Y, Hayashi T, Nephrology, dialysis, transplantation, official publication of, the, European Dialysis, Transplant Association, European Renal Association

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association　Vol. 26　No. 6　p. 1838-1846　2011/06

Guideline-practice gap in the management of predialysis chronic kidney disease mineral bone disorder in Japan.

Hamano T, Fujii N, Matsui I, Nakano C, Inoue K, Tomida K, Mikami S, Okada N, Tsubakihara Y, Rakugi H, Isaka Y, Therapeutic apheresis, dialysis, official peer-reviewed journal of, the International Society for Apheresis, the Japanese, Society for Apheresis, the Japanese, Society for Dialysis Therapy, v, Suppl

Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy　Vol. 15 Suppl 1　p. 2-8　2011/06

オートファジーは近位尿細管細胞のホメオスタシスを維持する

高畠義嗣, 木村友則, 高橋篤史, 難波倫子, 貝森淳哉, 松井功, 北村温美, 松阪泰二, 新村文男, 楽木宏実, 猪阪善隆

日本腎臓学会誌　Vol. 53　No. 3　p. 385-385　2011/05/25　Research paper (scientific journal)

急性腎障害に対抗するオートファジー

木村友則, 高畠義嗣, 高橋篤史, 難波倫子, 松井功, 貝森淳哉, 北村温美, 新村文男, 松阪泰二, 楽木宏実, 猪阪善隆

日本腎臓学会誌　Vol. 53　No. 3　p. 383-383　2011/05/25　Research paper (scientific journal)

腎虚血再灌流障害における卵膜由来間葉系幹細胞を用いた治療効果の検討

津田 秀年, 山原 研一, 奥見 雅由, 矢澤 浩治, 堀尾 勝, 貝森 淳哉, 猪阪 善隆, 池田 智明, 高原 史郎

日本腎臓学会誌　Vol. 53　No. 3　p. 388-388　2011/05　Research paper (scientific journal)

High prevalence of obstructive sleep apnea and its association with renal function among nondialysis chronic kidney disease patients in Japan: a cross-sectional study.

Sakaguchi Y, Shoji T, Kawabata H, Niihata K, Suzuki A, Kaneko T, Okada N, Isaka Y, Rakugi H, Tsubakihara Y, Clinical journal of, the American Society of Nephrology, CJASN, vo

Clinical journal of the American Society of Nephrology : CJASN　Vol. 6　No. 5　p. 995-1000　2011/05

Autophagy protects the proximal tubule from degeneration and acute ischemic injury.

Kimura T, Takabatake Y, Takahashi A, Kaimori JY, Matsui I, Namba T, Kitamura H, Niimura F, Matsusaka T, Soga T, Rakugi H, Isaka Y, Jour, al, American Society of Nephrology, JASN, vo

Journal of the American Society of Nephrology : JASN　Vol. 22　No. 5　p. 902-913　2011/05

Long-term outcome of pediatric renal transplantation: a single center experience.

Abe T, Ichimaru N, Kakuta Y, Okumi M, Imamura R, Isaka Y, Takahara S, Kokado Y, Okuyama A

Clinical transplantation　Vol. 25　No. 3　p. 388-394　2011/05

Epigallocatechin-3-gallate protects kidneys from ischemia reperfusion injury by HO-1 upregulation and inhibition of macrophage infiltration.

Kakuta Y, Okumi M, Isaka Y, Tsutahara K, Abe T, Yazawa K, Ichimaru N, Matsumura K, Hyon SH, Takahara S, Nonomura N

Transplant international : official journal of the European Society for Organ Transplantation　Vol. 24　No. 5　p. 514-522　2011/05　Research paper (scientific journal)

A case of superior mesenteric artery occlusion occuring one month after dialysis initiation

YASUDA Keiko, SASAKI Koichi, HATANAKA Masaki, ISAKA Yoshitaka, RAKUGI Hiromi, HAYASHI Terumasa

Journal of Japanese Society for Dialysis Therapy　Vol. 44　No. 4　p. 323-328　2011/04/28　Research paper (scientific journal)

Successful Preservation of the Kidney Grafts under Desiccating Conditions with a Mixture of Carbon Monoxide and Oxygen Gases in Rat Kidney Transplantation Model.

T. Abe, X. -K. Li, M. Okumi, N. Hatayama, L. Xie, Y. Kakuta, K. Tsutahara, K. Yazawa, J. Kaimori, Y. Isaka, S. Takahara, N. Nonomura

AMERICAN JOURNAL OF TRANSPLANTATION　Vol. 11　p. 498-499　2011/04

Long-term prognostic implication of post-angiographic acute kidney injury and hemodynamic instability

Tomonori Kimura, Yoshitaka Isaka, Terumasa Hayashi

Acute Kidney Injury: Causes, Diagnosis, and Treatments　p. 51-67　2011/02　Part of collection (book)

Haemorrhagic shock induced by subcutaneous insulin injection

Tomonori Kimura, Kazunori Inoue, Hiroki Omori, Yasuyuki Nagasawa, Yoshitaka Isaka

NDT Plus　Vol. 4　No. 1　p. 79-80　2011/02　Research paper (scientific journal)

CD28 superagonist-induced regulatory T cell expansion ameliorates mesangioproliferative glomerulonephritis in rats.

Miyasato K, Takabatake Y, Kaimori J, Kimura T, Kitamura H, Kawachi H, Li XK, Hünig T, Takahara S, Rakugi H, Isaka Y, Clinical, experimental nephrology, v

Clinical and experimental nephrology　Vol. 15　No. 1　p. 50-57　2011/02

Combination of Tonsillectomy and Corticosteroid Suppresses Recurrence of Urinary Protein or Occult Blood in Patients with IgA Nephropathy, Compared with Corticosteroid Alone

Hirotsugu Iwatani, Atsushi Takahashi, Ryohei Yamamoto, Yasuyuki Nagasawa, Arata Horii, Tadashi Kitahara, Hidenori Inohara, Atsushi Yamauchi, Enyu Imai, Hiromi Rakugi, Yoshitaka Isaka

RECENT ADVANCES IN TONSILS AND MUCOSAL BARRIERS OF THE UPPER AIRWAYS　Vol. 72　p. 198-198　2011　Research paper (scientific journal)

Urinary Type IV Collagen in Nondiabetic Kidney Disease

Yoshiyuki Furumatsu, Yasuyuki Nagasawa, Tatsuya Shoji, Ryohei Yamamoto, Kenichiro Iio, Isao Matsui, Yoshitsugu Takabatake, Jun-ya Kaimori, Hirotsugu Iwatani, Tetsuya Kaneko, Yoshiharu Tsubakihara, Enyu Imai, Yoshitaka Isaka, Hiromi Rakugi

NEPHRON CLINICAL PRACTICE　Vol. 117　No. 2　p. C160-C166　2011　Research paper (scientific journal)

Urinary type IV collagen in nondiabetic kidney disease.

Furumatsu Y, Nagasawa Y, Shoji T, Yamamoto R, Iio K, Matsui I, Takabatake Y, Kaimori JY, Iwatani H, Kaneko T, Tsubakihara Y, Imai E, Isaka Y, Rakugi H, Nephron. Clinical, practice

Nephron. Clinical practice　Vol. 117　No. 2　p. c160-6　2011

A superagonistic monoclonal antibody for CD28 ameliorates crescentic glomerulonephritis in wistar-kyoto rats.

Takabatake Y, Li XK, Mizui M, Miyasato K, Matsui I, Kawada N, Imai E, Hünig T, Takahara S, Wada T, Furuichi K, Rakugi H, Isaka Y, Molecular medicine, Cambridge, Mas

Molecular medicine (Cambridge, Mass.)　Vol. 17　No. 7-8　p. 686-696　2011　Research paper (scientific journal)

Microarray analysis of tonsils of IgA nephropathy patients.

Iwatani H, Iio K, Nagasawa Y, Yamamoto R, Horii A, Okuzaki D, Inohara H, Nojima H, Imai E, Rakugi H, Isaka Y, Advances in oto-rhino-laryngology

Advances in oto-rhino-laryngology　Vol. 72　p. 75-78　2011　Research paper (scientific journal)

The authors reply

Isao Matsui, Takayuki Hamano, Satoshi Mikami, Hiromi Rakugi, Yoshitaka Isaka

Kidney International　Vol. 78　No. 11　p. 1188-1189　2010/12　Research paper (scientific journal)

Increased fetuin-A levels following treatment with a vitamin D analog Reply

Isao Matsui, Takayuki Hamano, Satoshi Mikami, Hiromi Rakugi, Yoshitaka Isaka

KIDNEY INTERNATIONAL　Vol. 78　No. 11　p. 1188-1189　2010/12　Research paper (scientific journal)

A SUPERAGONISTIC MONOCLONAL ANTIBODY FOR CD28 AMELIORATED CRESCENTIC GLOMERULONEPHRITIS IN WISTAR-KYOTO RATS

Yoshitsugu Takabatake, Xiao-Kang Li, Kenro Miyasato, Enyu Imai, Thomas Hunig, Shiro Takahara, Hiromi Rakugi, Yoshitaka Isaka

JOURNAL OF GENE MEDICINE　Vol. 12　No. 12　p. 1049-1050　2010/12　Research paper (scientific journal)

SIRNA FOR P53 PROTRCTS KIDNEYS FROM ISCHEMIA-REPERFUSION INJURY ON EXPERIMENTAL RAT KIDNEY TRANSPLANTATION MODEL

Yoshitaka Isaka, Ryoichi Imamura, Ruben M. Sandoval, Bruce A. Molitoris, Hiromi Rakugi, Shiro Takahara

JOURNAL OF GENE MEDICINE　Vol. 12　No. 12　p. 1038-1038　2010/12　Research paper (scientific journal)

Induction of Donor-Specific Tolerance Using Superagonistic CD28 Antibody in Rat Renal Allografts: Regulatory T-Cell Expansion Before Engraftment May Be Important

Haruhito Azuma, Yoshitaka Isaka, Hayahito Nomi, Teruo Inamoto, Xiao-Kang Li, Tomas Hounig, Yoshitsugu Takabatake, Naotsugu Ichimaru, Naokazu Ibuki, Kunio Matsumoto, Takanobu Ubai, Yoji Katsuoka, Shiro Takahara

TRANSPLANTATION　Vol. 90　No. 12　p. 1328-1335　2010/12　Research paper (scientific journal)

Commensal microbiota induce LPS hyporesponsiveness in colonic macrophages via the production of IL-10.

Ueda Y, Kayama H, Jeon SG, Kusu T, Isaka Y, Rakugi H, Yamamoto M, Takeda K, Interna

International immunology　Vol. 22　No. 12　p. 953-962　2010/12　Research paper (scientific journal)

Specialist care and improved long-term survival of dialysis patients.

Furumatsu Y, Nagasawa Y, Yamamoto R, Iio K, Iwatani H, Matsui I, Takabatake Y, Kawada N, Shoji T, Imai E, Isaka Y, Rakugi H

Nephrol Dial Transplant　2010/12　Research paper (scientific journal)

Allogenic fetal membrane-derived mesenchymal stem cells contribute to renal repair in experimental glomerulonephritis.

Hidetoshi Tsuda, Kenichi Yamahara, Shin Ishikane, Kentaro Otani, Atsuhiro Nakamura, Kazutomo Sawai, Naotsugu Ichimaru, Masaharu Sada, Akihiko Taguchi, Hiroshi Hosoda, Masahiro Tsuji, Hiroshi Kawachi, Masaru Horio, Yoshitaka Isaka, Kenji Kangawa, Shiro Takahara, Tomoaki Ikeda

American journal of physiology. Renal physiology　Vol. 299　No. 5　2010/11　Research paper (scientific journal)

保存期慢性腎臓病患者における脳性ナトリウム利尿ペプチドと腎機能予後についての検討

安田 圭子, 木村 友則, 小尾 佳嗣, 佐々木 公一, 畑中 雅喜, 猪阪 善隆, 楽木 宏実, 林 晃正

日本腎臓学会誌　Vol. 52　No. 8　p. 1007-1014　2010/11　Research paper (scientific journal)

Fetuin-mineral complex reflects extraosseous calcification stress in CKD.

Hamano T, Matsui I, Mikami S, Tomida K, Fujii N, Imai E, Rakugi H, Isaka Y, Jour, al, American Society of Nephrology, JASN, v

Journal of the American Society of Nephrology : JASN　Vol. 21　No. 11　p. 1998-2007　2010/11

臓器保存の現状と将来の展望 卵膜由来間葉系幹細胞(FM-MSC)移植による腎虚血再還流障害に対する治療効果の検討

津田 秀年, 山原 研一, 奥見 雅由, 矢澤 浩治, 貝森 淳哉, 猪阪 善隆, 池田 智明, 高原 史郎

Organ Biology　Vol. 17　No. 2　p. 181-181　2010/10

Impact of age and overt proteinuria on outcomes of stage 3 to 5 chronic kidney disease in a referred cohort.

Obi Y, Kimura T, Nagasawa Y, Yamamoto R, Yasuda K, Sasaki K, Kitamura H, Imai E, Rakugi H, Isaka Y, Hayashi T, Clinical journal of, the American Society of Nephrology, CJASN, vo

Clinical journal of the American Society of Nephrology : CJASN　Vol. 5　No. 9　p. 1558-1565　2010/09

Exercise-induced acute kidney injury with reversible posterior leukoencephalopathy syndrome.

Kimura T, Iio K, Imai E, Rakugi H, Isaka Y, Hayashi T

Clin Exp Nephrol　Vol. 14　No. 2　p. 173-175　2010/09　Research paper (scientific journal)

Cigarette smoking and progression of IgA nephropathy.

Yamamoto R, Nagasawa Y, Shoji T, Iwatani H, Hamano T, Kawada N, Inoue K, Uehata T, Kaneko T, Okada N, Moriyama T, Horio M, Yamauchi A, Tsubakihara Y, Imai E, Rakugi H, Isaka Y, American journal, of, kidney diseases, the official journal of, the National, Kidney Foundation

American journal of kidney diseases : the official journal of the National Kidney Foundation　Vol. 56　No. 2　p. 313-324　2010/08

生体腎移植ドナーの腎機能評価におけるイヌリンクリアランスの有用性

角田 洋一, 市丸 直嗣, 奥見 雅由, 矢澤 浩治, 貝森 淳哉, 高原 史郎, 猪阪 善隆, 今井 圓裕, 堀尾 勝

今日の移植　Vol. 23　No. 4　p. 499-503　2010/08

移植後1年目の移植腎プロトコール生検におけるIgM陽性の検討

角田 洋一, 斉藤 純, 蔦原 宏一, 阿部 豊文, 矢澤 浩治, 市丸 直嗣, 奥山 明彦, 岡 一雅, 京 昌弘, 小角 幸人, 猪阪 善隆, 高原 史郎

泌尿器科紀要　Vol. 56　No. 7　p. 424-424　2010/07

IgA腎症患者扁桃に特異的な細菌叢と扁桃摘出+ステロイドパルス療法の治療効果との相関の検討

長澤康行, 飯尾健一郎, 山本陵平, 古松慶之, 岩谷博次, 今井圓裕, 楽木宏実, 猪阪善隆, 福田真嗣, 大野博司

日本腎臓学会誌　Vol. 52　No. 3　p. 280-280　2010/05/25　Research paper (scientific journal)

ループス腎炎モデルマウスに対するCD28スーパーアゴニストの治療効果の検証

高畠 義嗣, 木村 友則, 宮里 研郎, 高橋 篤史, 植畑 拓也, 貝森 淳哉, 川田 典孝, 今井 圓裕, Hunig Thomas, 李 小康, 楽木 宏実, 猪阪 善隆

日本腎臓学会誌　Vol. 52　No. 3　p. 348-348　2010/05　Research paper (scientific journal)

Stage 3-5 CKDにおける尿蛋白と年齢の重要性

小尾 佳嗣, 木村 友則, 長澤 康行, 安田 圭子, 佐々木 公一, 山本 陵平, 北村 温美, 猪阪 善隆, 林 晃正

日本腎臓学会誌　Vol. 52　No. 3　p. 406-406　2010/05　Research paper (scientific journal)

Thy1糸球体腎炎モデルでの他家卵膜由来間葉系幹細胞移植による治療効果とそのメカニズム検討

津田 秀年, 山原 研一, 矢澤 浩治, 貝森 淳哉, 堀尾 勝, 河内 裕, 猪阪 善隆, 池田 智明, 高原 史郎

日本腎臓学会誌　Vol. 52　No. 3　p. 384-384　2010/05

透析導入期に発見された悪性リンパ腫の1例

神田 貴史, 植畑 拓也, 清水 一亘, 小尾 佳嗣, 新沢 真紀, 高橋 篤, 長澤 康行, 川田 典孝, 今井 圓裕, 猪阪 善隆

大阪透析研究会会誌　Vol. 28　No. 1　p. 94-94　2010/03

Carbamylated erythropoietin inhibits tubulointerstitial fibrosis in remnant kidney

Yoshitaka Isaka, Ryoichi Imamura, Shiro Takahara, Bruce A. Molitoris, Hiromi Rakugi

ENDOCRINE JOURNAL　Vol. 57　p. S616-S616　2010/03　Research paper (scientific journal)

Microarray analysis of tonsils in immunoglobulin A nephropathy patients.

Iio K, Nagasawa Y, Iwatani H, Yamamoto R, Horii A, Okuzaki D, Furumatsu Y, Inohara H, Nojima H, Imai E, Isaka Y, Rakugi H, Biochemical, biophysical research communications

Biochemical and biophysical research communications　Vol. 393　No. 4　p. 565-570　2010/03　Research paper (scientific journal)

Utility of the Japanese GFR estimation equation for evaluating potential donor kidney function.

Kakuta Y, Okumi M, Ichimaru N, Abe T, Nonomura N, Okuyama A, Kojima Y, Isaka Y, Takahara S, Imai E, Horio M

Clinical and experimental nephrology　Vol. 14　No. 1　p. 63-67　2010/02　Research paper (scientific journal)

ラットシクロスポリン腎症モデルにおいてカルバミル化エリスロポエチンは造血作用なく腎保護効果を有する

阿部 豊文, 猪阪 善隆, 今村 亮一, 斉藤 純, 角田 洋一, 蔦原 宏一, 矢澤 浩治, 市丸 直嗣, 高原 史郎, 奥山 明彦

日本泌尿器科学会雑誌　Vol. 101　No. 2　p. 496-496　2010/02

Prevention of graft-versus-host diseases by in vivo supCD28mAb-expanded antigen-specific nTreg cells

Yusuke Kitazawa, Xiao-Kang Li, Zhong Liu, Hiromitsu Kimura, Yoshitaka Isaka, Thomas Hünig, Shiro Takahara

Cell Transplantation　Vol. 19　No. 6-7　p. 765-774　2010　Research paper (scientific journal)

Intravital Two-Photon Microscopy Assessment of Renal Protection Efficacy of siRNA for p53 in Experimental Rat Kidney Transplantation Models

Ryoichi Imamura, Yoshitaka Isaka, Ruben M. Sandoval, Asaf Ori, Swetlana Adamsky, Elena Feinstein, Bruce A. Molitoris, Shiro Takahara

CELL TRANSPLANTATION　Vol. 19　No. 12　p. 1659-1670　2010　Research paper (scientific journal)

[Plasma B-type natriuretic peptide level predicts the renal outcome in patients with chronic kidney disease].

Yasuda K, Kimura T, Obi Y, Sasaki K, Hatanaka M, Isaka Y, Rakugi H, Hayashi T, Nihon Jinzo, Gakkai shi

Nihon Jinzo Gakkai shi　Vol. 52　No. 8　p. 1007-1014　2010

Campylobacter fetus peritonitis in a patient with an unused embedded subcutaneous peritoneal catheter.

Inoue K, Kitamura H, Nagasawa Y, Kawada N, Isaka Y, Rakugi H, Peritoneal dialysis international, journal of the International Society for Peritoneal Dialysis

Vol. 30　No. 2　p. 253-254　2010

Post-transplant lymphoproliferative disorder following renal transplantation: a single-center experience over 40 years.

Abe T, Ichimaru N, Kokado Y, Maeda T, Kakuta Y, Okumi M, Imamura R, Nonomura N, Isaka Y, Takahara S, Okuyama A

International journal of urology : official journal of the Japanese Urological Association　Vol. 17　No. 1　p. 48-54　2010/01　Research paper (scientific journal)

Discrepancy between serum levels of low molecular weight proteins in acute kidney injury model rats with bilateral ureteral obstruction and bilateral nephrectomy

Hidetoshi Tsuda, Yoshitaka Isaka, Shiro Takahara, Masaru Horio

CLINICAL AND EXPERIMENTAL NEPHROLOGY　Vol. 13　No. 6　p. 567-570　2009/12　Research paper (scientific journal)

A candidate gene approach to genetic prognostic factors of IgA nephropathy--a result of Polymorphism REsearch to DIstinguish genetic factors Contributing To progression of IgA Nephropathy (PREDICT-IgAN).

Ryohei Yamamoto, Yasuyuki Nagasawa, Tatsuya Shoji, Kazunori Inoue, Takuya Uehata, Tetsuya Kaneko, Tomonori Okada, Atsushi Yamauchi, Yoshiharu Tsubakihara, Enyu Imai, Yoshitaka Isaka, Hiromi Rakugi

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association　Vol. 24　No. 12　p. 3686-94　2009/12

The impact of diabetes mellitus on vitamin D metabolism in predialysis patients.

Tanaka H, Hamano T, Fujii N, Tomida K, Matsui I, Mikami S, Nagasawa Y, Ito T, Moriyama T, Horio M, Imai E, Isaka Y, Rakugi H, Bone, vo

Bone　Vol. 45　No. 5　p. 949-955　2009/11　Research paper (scientific journal)

Mineral complexes and vascular calcification Response

Isao Matsui, Takayuki Hamano, Satoshi Mikami, Yoshitaka Isaka, Hiromi Rakugi

KIDNEY INTERNATIONAL　Vol. 76　No. 8　p. 915-916　2009/10　Research paper (scientific journal)

腎移植ドナーにおける腎機能評価法

角田 洋一, 阿部 豊文, 奥見 雅由, 市丸 直嗣, 猪阪 善隆, 高原 史郎, 堀尾 勝, 今井 圓裕

大阪透析研究会会誌　Vol. 27　No. 2　p. 281-281　2009/09

シクロスポリン腎症に対するカミバミル化エリスロポエチンの腎保護効果

阿部 豊文, 猪阪 善隆, 今村 亮一, 齊藤 純, 角田 洋一, 蔦原 宏一, 奥見 雅由, 市丸 直嗣, 高原 史郎, 奥山 明彦

移植　Vol. 44　No. 総会臨時　p. 220-220　2009/09

生体腎移植ドナーの腎機能評価における血清クレアチニンによるGFR推算式と血清シスタチンCによるGFR推算式の比較検討

角田 洋一, 斉藤 純, 蔦原 宏一, 阿部 豊文, 奥見 雅由, 矢澤 浩治, 市丸 直嗣, 猪阪 善隆, 高原 史郎, 山内 裕二, 児島 康行

移植　Vol. 44　No. 総会臨時　p. 298-298　2009/09

ANCA陽性を示したクリオグロブリン血症の一例

川端 裕彰, 木村 友則, 井上 和則, 大森 弘基, 山本 陵平, 長澤 康行, 今井 圓裕, 楽木 宏実, 猪阪 善隆

日本腎臓学会誌　Vol. 51　No. 6　p. 780-780　2009/08　Research paper (scientific journal)

縦断的脳幹・脊髄炎を合併したSLEに血漿交換が奏功した一例

北庄司 絵美, 木村 友則, 井上 和則, 大森 弘基, 山本 陵平, 長澤 康行, 今井 圓裕, 楽木 宏実, 猪阪 善隆

日本腎臓学会誌　Vol. 51　No. 6　p. 785-785　2009/08

多彩な塞栓症状を呈した糖尿病性腎症急性増悪の一例

北庄司 絵美, 木村 友則, 井上 和則, 大森 広基, 山本 陵平, 長澤 康行, 今井 圓裕, 楽木 宏実, 猪阪 善隆

日本腎臓学会誌　Vol. 51　No. 6　p. 793-793　2009/08

腎機能低下を呈し腎生検を施行したLecithin Cholesterol Acyltransferase(LCAT)欠損症の一例

末吉 弘尚, 大森 弘基, 山本 陵平, 井上 和則, 木村 友則, 長澤 康行, 猪阪 善隆

日本腎臓学会誌　Vol. 51　No. 6　p. 801-801　2009/08

Fabry病に対し血液透析導入後に酵素補充療法を行った一例

川端 裕彰, 木村 友則, 井上 和則, 大森 弘基, 山本 陵平, 長澤 康行, 今井 圓裕, 楽木 宏実, 猪阪 善隆

日本腎臓学会誌　Vol. 51　No. 6　p. 801-801　2009/08　Research paper (scientific journal)

SMAP法にてカテーテル留置中に腹膜炎を来たした一症例

伊藤 大介, 井上 和則, 北村 温美, 川田 典孝, 窪田 実, 木村 友則, 大森 弘基, 山本 陵平, 長澤 康行, 猪阪 善隆, 楽木 宏美

日本腎臓学会誌　Vol. 51　No. 6　p. 804-804　2009/08　Research paper (scientific journal)

抗GBM抗体陽性のループス腎炎の一例

重原 万葉, 木村 友則, 高橋 篤史, 井上 和則, 大森 弘基, 山本 陵平, 長澤 康行, 今井 圓裕, 楽木 宏実, 猪阪 善隆

日本腎臓学会誌　Vol. 51　No. 6　p. 806-806　2009/08

低アルブミン血症を伴わないlight chain cast nephropathy(LCCN)の一例

木田 亨, 大森 弘基, 山本 陵平, 井上 和則, 木村 友則, 長澤 康行, 猪阪 善隆

日本腎臓学会誌　Vol. 51　No. 6　p. 809-809　2009/08

胃癌に対するS-1内服中に急性腎不全となり、血液浄化が必要であった一症例

井上 和則, 依藤 秀樹, 木村 友則, 大森 弘基, 古松 慶之, 山本 陵平, 長澤 康行, 猪阪 善隆, 楽木 宏美

日本腎臓学会誌　Vol. 51　No. 6　p. 810-810　2009/08　Research paper (scientific journal)

Active vitamin D and its analogue, 22-oxacalcitriol, ameliorate puromycin aminonucleoside-induced nephrosis in rats.

Isao Matsui, Takayuki Hamano, Kodo Tomida, Kazunori Inoue, Yoshitsugu Takabatake, Yasuyuki Nagasawa, Noritaka Kawada, Takahito Ito, Hiroshi Kawachi, Hiromi Rakugi, Enyu Imai, Yoshitaka Isaka

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association　Vol. 24　No. 8　p. 2354-61　2009/08

Negative effects of anemia on quality of life and its improvement by complete correction of anemia by administration of recombinant human erythropoietin in posttransplant patients.

Kawada N, Moriyama T, Ichimaru N, Imamura R, Matsui I, Takabatake Y, Nagasawa Y, Isaka Y, Kojima Y, Kokado Y, Rakugi H, Imai E, Takahara S

Clinical and experimental nephrology　Vol. 13　No. 4　p. 355-360　2009/08　Research paper (scientific journal)

The CXCL12 (SDF-1)/CXCR4 axis is essential for the development of renal vasculature.

Takabatake Y, Sugiyama T, Kohara H, Matsusaka T, Kurihara H, Koni PA, Nagasawa Y, Hamano T, Matsui I, Kawada N, Imai E, Nagasawa T, Rakugi H, Isaka Y, Jour, al, American Society of Nephrology, JASN, vo

J Am Soc Nephrol　Vol. 20　No. 8　p. 1714-1723　2009/08

Early plasma exchange for progressive liver failure in recipients of adult-to-adult living-related liver transplants

Ryohei Yamamoto, Yasuyuki Nagasawa, Shigeru Marubashi, Yoshiyuki Furumatsu, Hirotsugu Iwatani, Kenichiro Iio, Isao Matsui, Keizo Dono, Enyu Imai, Morito Monden, Yoshitaka Isaka

Blood Purification　Vol. 28　No. 1　p. 40-46　2009/07/01　Research paper (scientific journal)

Usefulness of bone resorption markers in hemodialysis patients.

Hamano T, Tomida K, Mikami S, Matsui I, Fujii N, Imai E, Rakugi H, Isaka Y, Bone, vo, Suppl

Bone　Vol. 45 Suppl 1　p. S19-25　2009/07

ラット腎移植モデルにおけるp53siRNA投与による虚血再灌流障害抑制に関する検討

今村 亮一, 角田 洋一, 阿部 豊文, 奥見 雅由, 市丸 直嗣, 奥山 明彦, 猪阪 善隆, 高原 史郎

泌尿器科紀要　Vol. 55　No. 7　p. 454-454　2009/07

Reply

Yoshiyasu Ueda, Masamitsu Fujii, Yoshitaka Isaka

Nephrology Dialysis Transplantation　Vol. 24　No. 6　2009/06　Research paper (scientific journal)

Acid-base balance in acute panic attack Reply

Yoshiyasu Ueda, Masamitsu Fujii, Yoshitaka Isaka

NEPHROLOGY DIALYSIS TRANSPLANTATION　Vol. 24　No. 6　p. 2007-2007　2009/06　Research paper (scientific journal)

Quiz page June 2009: worsening kidney function with a history of urolithiasis.

Tomonori Kimura, Keiko Yasuda, Yoshitsugu Obi, Ken-ichiro Kobayashi, Tomiko Kuhara, Yoshitaka Isaka, Enyu Imai, Hiromi Rakugi, Terumasa Hayashi

American journal of kidney diseases : the official journal of the National Kidney Foundation　Vol. 53　No. 6　2009/06

Massive and rapid left ventricular calcification.

Iwatani H, Tomida K, Nagasawa Y, Imai E, Rakugi H, Isaka Y, NDT plus

NDT plus　Vol. 2　No. 3　p. 259-260　2009/06　Research paper (scientific journal)

Amelioration of experimental autoimmune encephalomyelitis by curcumin treatment through inhibition of IL-17 production

Lin Xie, Xiao-Kang Li, Naoko Funeshima-Fuji, Hiromitsu Kimura, Yoh Matsumoto, Yoshitaka Isaka, Shiro Takahara

International Immunopharmacology　Vol. 9　No. 5　p. 575-581　2009/05　Research paper (scientific journal)

Fully phosphorylated fetuin-A forms a mineral complex in the serum of rats with adenine-induced renal failure.

Matsui I, Hamano T, Mikami S, Fujii N, Takabatake Y, Nagasawa Y, Kawada N, Ito T, Rakugi H, Imai E, Isaka Y

Kidney Int　2009/05　Research paper (scientific journal)

IgA腎症患者扁桃に特異的な細菌叢の網羅的検討

長澤康行, 飯尾健一郎, 福田真嗣, 山本陵平, 古松慶之, 岩谷博次, 今井圓裕, 猪阪善隆, 楽木宏実, 大野博司

日本腎臓学会誌　Vol. 51　No. 3　p. 284-284　2009/04/25　Research paper (scientific journal)

冠動脈造影後に病態が安定している患者と不安定の患者における造影剤誘発性急性腎障害の発生と短期成績(The incidence and short-term outcomes of contrast-induced acute kidney injury in stable and unstable population after coronary artery angiography)

木村 友則, 小尾 佳嗣, 安田 圭子, 猪阪 善隆, 今井 圓裕, 楽木 宏美, 林 晃正

日本腎臓学会誌　Vol. 51　No. 3　p. 273-273　2009/04　Research paper (scientific journal)

ラット腎移植モデルにおけるp53siRNAは虚血再灌流傷害から腎を保護する

猪阪 善隆, 今村 亮一, 高原 史郎, 楽木 宏実

医工学治療　Vol. 21　No. Suppl.　p. 105-105　2009/04　Research paper (scientific journal)

ラット腎移植モデルにおいてp53siRNAは腎虚血再灌流傷害を抑制する

今村 亮一, 猪阪 善隆, 市丸 直嗣, 高田 晋吾, 松宮 清美, 奥山 明彦, 高原 史郎

日本腎臓学会誌　Vol. 51　No. 3　p. 300-300　2009/04

ラット慢性腎不全モデルにおけるcarbamylated erythropoietinの臓器保護作用に関する検討

今村 亮一, 猪阪 善隆, 市丸 直嗣, 高田 晋吾, 松宮 清美, 奥山 明彦, 高原 史郎

日本腎臓学会誌　Vol. 51　No. 3　p. 373-373　2009/04

SYSTEMIC ADMINISTRATION OF SIRNA TARGETING P53 PROTECTS KIDNEYS FROM ISCHEMIA-REPERFUSION INJURY EXPERIMENTAL RAT KIDNEY TRANSPLANTATION MODEL.

Imamura Ryoichi, Isaka Yoshitaka, Sandoval Ruben M. Jr, Kakuta Yoichi, Abe Toyofumi, Okumi Masayoshi, Ichimaru Naotsugu, Takada Shingo, Matsumiya Kiyomi, Molitoris Bruce A, Okuyama Akihiko, Takahara Shiro

JOURNAL OF UROLOGY　Vol. 181　No. 4　2009/04

Serum 25-hydroxyvitamin D as an independent determinant of 1-84 PTH and bone mineral density in non-diabetic predialysis CKD patients.

Tomida K, Hamano T, Mikami S, Fujii N, Okada N, Matsui I, Nagasawa Y, Moriyama T, Ito T, Imai E, Isaka Y, Rakugi H

Bone　Vol. 44　p. 678-683　2009/04　Research paper (scientific journal)

Severe adverse effects of 5-fluorouracil in S-1 were lessened by haemodialysis due to elimination of the drug.

Inoue K, Nagasawa Y, Yamamoto R, Omori H, Kimura T, Tomida K, Furumatsu Y, Imai E, Isaka Y, Rakugi H, NDT plus

NDT plus　Vol. 2　No. 2　p. 152-154　2009/04

腎移植におけるIVIGを用いた脱感作療法と抗体関連型拒絶反応に対する治療成績

角田 洋一, 阿部 豊文, 奥見 雅由, 市丸 直嗣, 猪阪 善隆, 高原 史郎, 佐田 正晴

MHC: Major Histocompatibility Complex　Vol. 16　No. 1　p. 67-67　2009/04

Exaggerated compensatory response to acute respiratory alkalosis in panic disorder is induced by increased lactic acid production

Yoshiyasu Ueda, Masayo Aizawa, Atsushi Takahashi, Masamitsu Fujii, Yoshitaka Isaka

NEPHROLOGY DIALYSIS TRANSPLANTATION　Vol. 24　No. 3　p. 825-828　2009/03　Research paper (scientific journal)

【リツキシマブによる抗体抑制 腎移植を中心に】ABO血液型不適合腎移植および抗体関連型拒絶反応に対するリツキシマブの使用経験

角田 洋一, 奥見 雅由, 市丸 直嗣, 阿部 豊文, 猪阪 善隆, 吉岡 俊昭, 阪口 勝彦, 奥山 明彦, 高原 史郎

今日の移植　Vol. 22　No. 2　p. 204-208　2009/03

Pharmacokinetics of Olmesartan Medoxomil in Hemodialysis Patients -little effect of dialysis upon its pharmacokinetics-

Hirotaka Tanaka, Yasuyuki Nagasawa, Isao Matsui, Takayuki Hamano, Hirotsugu Iwatani, Noritaka Kawada, Masaru Horio, Takahito Ito, Yoshitaka Isaka, Enyu Imai

Clinical and Experimental Nephrology　Vol. 13　No. 1　p. 61-5　2009/02　Research paper (scientific journal)

ラット腎移植モデルにおいてp53siRNAは腎虚血再灌流傷害を抑制する

今村 亮一, 猪阪 善隆, Sandoval Ruben M, 角田 洋一, 阿部 豊文, 奥見 雅由, 市丸 直嗣, 高田 晋吾, 松宮 清美, Molitoris Bruce A, 奥山 明彦, 高原 史郎

日本泌尿器科学会雑誌　Vol. 100　No. 2　p. 180-180　2009/02

腎移植ドナーの術前腎機能評価におけるイヌリンクリアランスの有用性

角田 洋一, 奥見 雅由, 阿部 豊文, 今村 亮一, 市丸 直嗣, 野々村 祝夫, 奥山 明彦, 猪阪 善隆, 高原 史郎, 小角 幸人, 児島 康行

日本泌尿器科学会雑誌　Vol. 100　No. 2　p. 254-254　2009/02

維持期腎移植後患者における腎性副甲状腺機能亢進症の超音波スクリーニングとその関連因子についての臨床的検討

市丸 直嗣, 角田 洋一, 阿部 豊文, 奥見 雅由, 今村 亮一, 児島 康行, 藤井 直彦, 濱野 高行, 冨田 弘道, 猪阪 善隆, 高原 史郎, 奥山 明彦

日本泌尿器科学会雑誌　Vol. 100　No. 2　p. 255-255　2009/02

シクロスポリン腎毒性モデルに対するcarbamylated erythropoietin(CEPO)の臓器保護作用

阿部 豊文, 今村 亮一, 猪阪 善隆, 角田 洋一, 奥見 雅由, 市丸 直嗣, 奥山 明彦, 高原 史郎

日本泌尿器科学会雑誌　Vol. 100　No. 2　p. 353-353　2009/02

Superagonist CD28 antibody preferentially expanded Foxp3-expressing nTreg cells and prevented graft-versus-host diseases.

Kitazawa Y, Fujino M, Li XK, Xie L, Ichimaru N, Okumi M, Nonomura N, Tsujimura A, Isaka Y, Kimura H, Hünig T, Takahara S

Cell transplantation　Vol. 18　No. 5　p. 627-637　2009　Research paper (scientific journal)

Carbamylated Erythropoietin (CEPO) Protects the Kidneys from Cyclosporine Nephropathy without Stimulating Erythropoiesis

Abe Toyofumi, Imamura Ryoichi, Isaka Yoshitaka, Kakuta Yoichi, Okumi Masayoshi, Ichimaru Naotsugu, Okuyama Akihiko, Takahara Shiro

AMERICAN JOURNAL OF TRANSPLANTATION　Vol. 9　2009

In vivo transfer of small interfering RNA or small hairpin RNA targeting glomeruli.

Takabatake Y, Isaka Y, Imai E

Methods Mol Biol.　Vol. 466　p. 251-63　2009　Research paper (scientific journal)

TANK is a negative regulator of Toll-like receptor signaling and is critical for the prevention of autoimmune nephritis

Kawagoe T, Takeuchi O, Takabatake Y, Kato H, Isaka Y, Tsujimura T, Akira S

Nat Immunol　Vol. 10　No. 9　p. 965-972　2009

Bcl-2 protects tubular epithelial cells from ischemia/reperfusion injury by dual mechanisms

Isaka Y, Suzuki C, Abe T, Okumi M, Ichimaru N, Imamura R, Kakuta Y, Matsui I, Takabatake Y, Rakugi H, Shimizu S

Transplant Proc. 2009 Jan-Feb;41(1):52-4.　Vol. 41　No. 1　p. 52-54　2009/01

PTX待機中にcinacalcetを投与した原発性副甲状腺機能亢進症の1症例

濱野 高行, 木村 友則, 大森 弘基, 井上 和則, 山本 陵平, 長澤 康行, 今井 圓裕, 猪阪 善隆, 楽木 宏美

腎と骨代謝　Vol. 21　No. 4　p. 342-342　2008/10

2次性副甲状腺機能亢進症の治療がFetuin-A/AHSGの存在様式に与える影響

三上 聡司, 松井 功, 濱野 高行, 冨田 弘道, 田中 啓隆, 今井 圓裕, 猪阪 善隆, 楽木 宏美

腎と骨代謝　Vol. 21　No. 4　p. 348-348　2008/10

臓器移植関連の生体イメージング p53siRNAはラット腎移植モデルにおける虚血再灌流傷害を軽減する 2-photon microscopyを用いた生体イメージング

今村 亮一, 猪阪 善隆, Sandoval Ruben M., Molitoris Bruce A., 奥山 明彦, 高原 史郎

Organ Biology　Vol. 15　No. 3　p. 247-247　2008/10

Valvular injury in a patient with PR3-ANCA-associated glomerulonephritis

Hirotsugu Iwatani, Yasuyuki Nagasawa, Kazumasa Oka, Yoshitaka Isaka, Enyu Imai

Nature Clinical Practice Nephrology　Vol. 4　No. 10　p. 576-582　2008/10　Research paper (scientific journal)

三次性副甲状腺機能亢進症の有病率の超音波検査による評価(UltraSonographical Evaluation of the Prevalence of Tertiary Hyperparathyroidism)

冨田 道弘, 濱野 高行, 田中 啓隆, 今井 圓裕, 樂木 宏美, 藤井 直彦, 市丸 直嗣, 猪阪 善隆, 高原 史郎

腎と骨代謝　Vol. 21　No. 4　p. 351-351　2008/10

腎臓の虚血障害とエリスロポエチン(Renal hypoxia and erythropoietin) エリスロポエチンによる腎保護作用の展望

猪阪 善隆, 今村 亮一, 北村 温美, 今井 圓裕, 楽木 宏実, 高原 史郎

移植　Vol. 43　No. 総会臨時　p. 207-207　2008/09　Research paper (scientific journal)

ラット腎移植モデルにおけるp53siRNAは虚血再灌流傷害から腎を保護する

今村 亮一, 猪阪 善隆, 奥山 明彦, 高原 史郎

移植　Vol. 43　No. 総会臨時　p. 258-258　2008/09

腎移植患者に対するカンデサルタンによる蛋白尿減少効果の検討

奥見 雅由, 市丸 直嗣, 守山 敏樹, 阿部 豊文, 今村 亮一, 小角 幸人, 児島 康行, 猪阪 善隆, 奥山 明彦, 高原 史郎

移植　Vol. 43　No. 総会臨時　p. 278-278　2008/09

'O', erythropoietin carbamoylation versus carbamylation - Reply

Harumi Kitamura, Yoshitaka Isaka

NEPHROLOGY DIALYSIS TRANSPLANTATION　Vol. 23　No. 9　p. 3033-3034　2008/09　Research paper (scientific journal)

腎移植医療に対する革新的治療法の期待

猪阪 善隆, 李 小康, 東 治人, 山田 和彦, 今村 亮一, 水井 理之, 高畠 義嗣, Huenig Tomas, Molitoris A. Bruce, 今井 圓裕, 楽木 宏実, 高原 史郎

移植　Vol. 43　No. 総会臨時　p. 215-215　2008/09　Research paper (scientific journal)

Oligonucleotidic therapeutics.

Isaka Y, Imai E, Takahara S, Rakugi H, Expert opinion on, drug discovery

Expert opinion on drug discovery　Vol. 3　No. 9　p. 991-996　2008/09

悪性腫瘍 腎移植患者に発生した悪性腫瘍に関する検討

野々村 祝夫, 角田 洋一, 奥見 雅由, 阿部 豊文, 今村 亮一, 今尾 哲也, 市丸 直嗣, 猪阪 善隆, 児島 康行, 小角 幸人, 高原 史郎, 奥山 明彦

移植　Vol. 43　No. 総会臨時　p. 198-198　2008/09

イヌリンクリアランス実施の重要性 eGFRの限界と測定法の簡易化 腎移植ドナーにおける腎機能評価法

角田 洋一, 奥見 雅由, 阿部 豊文, 今村 亮一, 市丸 直嗣, 猪阪 善隆, 高原 史郎, 山内 裕二, 児島 康行, 堀尾 勝, 今井 圓裕

移植　Vol. 43　No. 総会臨時　p. 220-220　2008/09

ラット腎虚血再灌流傷害モデルにおけるCarbamylated erythropoietinの臓器保護作用に関する検討

今村 亮一, 猪阪 善隆, 角田 洋一, 阿部 豊文, 奥見 雅由, 市丸 直嗣, 奥山 明彦, 高原 史郎

移植　Vol. 43　No. 総会臨時　p. 409-409　2008/09

Pregnancy after renal transplantation: a single-center experience.

Abe T, Ichimaru N, Okumi M, Imamura R, Isaka Y, Takahara S, Kokado Y, Okuyama A

International journal of urology : official journal of the Japanese Urological Association　Vol. 15　No. 7　p. 587-592　2008/07　Research paper (scientific journal)

Treatment adherence in renal transplant recipients: a questionnaire survey on immunosuppressants.

Ichimaru N, Kakuta Y, Abe T, Okumi M, Imamura R, Isaka Y, Nonomura N, Kojima Y, Okuyama A, Takahara S

Transplantation proceedings　Vol. 40　No. 5　p. 1362-1365　2008/06

PTx前後でのFetuin-mineral complexの変化

三上 聡司, 松井 功, 濱野 高行, 冨田 弘道, 田中 啓隆, 片山 正哉, 猪阪 善隆, 伊藤 孝仁, 今井 圓裕

日本透析医学会雑誌　Vol. 41　No. Suppl.1　p. 595-595　2008/05　Research paper (scientific journal)

Vitamin Dはネフローゼラットの蛋白尿を減少させる

松井 功, 濱野 高行, 三上 聡司, 冨田 弘道, 田中 啓隆, 猪阪 善隆, 伊藤 孝仁, 今井 圓裕, 楽木 宏実

日本腎臓学会誌　Vol. 50　No. 3　p. 308-308　2008/04　Research paper (scientific journal)

保存期CKD-MBDにおける性差

藤井 直彦, 濱野 高行, 三上 聡司, 松井 功, 冨田 弘道, 田中 啓隆, 奥野 綾子, 山内 洋子, 伊藤 孝仁, 猪阪 善隆, 今井 圓裕

日本腎臓学会誌　Vol. 50　No. 3　p. 309-309　2008/04　Research paper (scientific journal)

Foxp3-expressing Regulatory T Cells Expanded With CD28 Superagonist Antibody Can Prevent Rat Cardiac Allograft Rejection

Yusuke Kitazawa, Masayuki Fujino, Takatoshi Sakai, Haruhito Azuma, Hiromitsu Kimura, Yoshitaka Isaka, Shiro Takahara, Thomas Hünig, Ryo Abe, Xiao-Kang Li

Journal of Heart and Lung Transplantation　Vol. 27　No. 4　p. 362-371　2008/04　Research paper (scientific journal)

Participation of autophagy in renal ischemia/reperfusion injury

Suzuki Chigure, Isaka Yoshitaka, Takabatake Yoshitsugu, Tanaka Hirotaka, Kolke Masato, Shibata Masahiro, Uchiyama Yasuo, Takahara Shiro, Iniai Enyu

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS　Vol. 368　No. 1　p. 100-106　2008/03/28　Research paper (scientific journal)

ABO不適合腎移植における腹腔鏡下脾摘術の臨床的検討

市丸 直嗣, 阿部 豊文, 奥見 雅由, 今村 亮一, 奥山 明彦, 猪阪 善隆, 高原 史郎, 小角 幸人, 吉岡 俊昭, 客野 宮治

日本泌尿器科学会雑誌　Vol. 99　No. 2　p. 308-308　2008/02

腎移植後PTLD 7症例の臨床的検討

阿部 豊文, 奥見 雅由, 今村 亮一, 市丸 直嗣, 奥山 明彦, 猪阪 善隆, 高原 史郎, 小角 幸人

日本泌尿器科学会雑誌　Vol. 99　No. 2　p. 478-478　2008/02

Prospects for Gene Therapy

Enyu Imai, Yoshitaka Isaka, Yoshitsugu Takabatake

Therapy in Nephrology &amp; Hypertension　p. 557-564　2008　Part of collection (book)

Glycocalyx damage estimated using colloidal iron staining

Daoxin Zhang, Yoshitaka Isaka, Ryoichi Imamura, Naotsugu Ichimaru, Yi Shi, Enyu Imai, Ye Tian, Aiji Ohtsuka, Shiro Takahara

Cell Transplantation　Vol. 17　No. 1-2　p. 159-163　2008　Research paper (international conference proceedings)

Nonerythropoietic derivative of erythropoietin protects against tubulointerstitial injury in a unilateral ureteral obstruction model.

Kitamura H, Isaka Y, Takabatake Y, Imamura R, Suzuki C, Takahara S, Imai E

Nephrol Dial Transplant.　Vol. 23　No. 5　p. 1521-8　2008　Research paper (scientific journal)

Renal artery injection for delivery of biological materials to the glomerulus.

Takabatake Y, Isaka Y, Imai E

Nephrology (Carlton).　Vol. 13　No. 1　p. 23-6　2008　Research paper (scientific journal)

Chronic deteriorating renal function and renal fibrosis.

Isaka Y, Takahara S, Imai E

Contrib Nephrol.　Vol. 159　p. 109-21　2008　Research paper (scientific journal)

Carbamylated erythropoietin improves angiogenesis and protects the kidneys from ischemia-reperfusion injury.

Imamura R, Okumi M, Isaka Y, Ichimaru N, Moriyama T, Imai E, Nonomura N, Takahara S, Okuyama A

Cell Transplant.　Vol. 17　No. 1-2　p. 135-41　2008　Research paper (scientific journal)

Serum osteoprotegerin as a screening tool for coronary artery calcification score in diabetic pre-dialysis patients.

Mikami S, Hamano T, Fujii N, Nagasawa Y, Isaka Y, Moriyama T, Matsuhisa M, Ito T, Imai E, Hori M

Hypertens Res.　Vol. 31　No. 6　p. 1163-1170　2008　Research paper (scientific journal)

Bcl-2 protects tubular epithelial cells from ischemia reperfusion injury by inhibiting apoptosis.

Suzuki C, Isaka Y, Shimizu S, Tsujimoto Y, Takabatake Y, Ito T, Takahara S, Imai E

Cell transplantation　Vol. 17　p. 223-229　2008

腎移植後の抗体関連型拒絶反応に対する経静脈性免疫グロブリン投与および血漿交換併用療法の経験

角田 洋一, 山口 誓司, 佐田 正晴, 永谷 憲歳, 阿部 豊文, 奥見 雅由, 今村 亮一, 市丸 直嗣, 吉岡 俊昭, 京 昌弘, 猪阪 善隆, 高原 史郎, 奥山 明彦

移植　Vol. 42　No. 6　p. 561-566　2007/12

HGF-MSP chimera protects kidneys from ischemia-reperfusion injury.

Xue F, Isaka Y, Takahara T, Imamura R, Suzuki C, Ichimaru N, Michieli P, Takahara S

Biochemical and biophysical research communications　Vol. 363　No. 2　p. 451-456　2007/11/16　Research paper (scientific journal)

ラット5/6腎摘モデルに対するcarbamylated erythropoietin(CEPO)の臓器保護作用に関する検討

阿部 豊文, 今村 亮一, 猪阪 善隆, 奥見 雅由, 市丸 直嗣, 高原 史郎, 奥山 明彦

移植　Vol. 42　No. 総会臨時　p. 279-279　2007/10

腎移植後の抗体関連型拒絶反応に対するIVIG療法

角田 洋一, 山口 誓司, 阿部 豊文, 今村 亮一, 奥見 雅由, 市丸 直嗣, 坂口 勝彦, 吉岡 俊昭, 京 昌弘, 久山 芳文, 佐田 正晴, 永谷 憲歳, 猪阪 善隆, 高原 史郎

MHC: Major Histocompatibility Complex　Vol. 14　No. 2　p. 147-147　2007/08

SuperagonistCD28抗体によるドナー特異的移植免疫寛容誘導

猪阪 善隆, 高原 史郎, 水井 理之, 高畠 義嗣, 今井 圓裕, 東 治人, 李 小康

日本臨床免疫学会会誌　Vol. 30　No. 4　p. 288-288　2007/08　Research paper (scientific journal)

Risedronate, an effective treatment for glucocorticoid-induced bone loss in CKD patients with or without concomitant active vitamin D (PRIUS-CKD)

Fujii N, Hamano T, Mikami S, Nagasawa Y, Isaka Y, Moriyama T, Horio M, Imai E, Hori M, Ito T

Nephrol Dial Transplant　Vol. 22　No. 6　p. 1601-7　2007/06　Research paper (scientific journal)

Erythropoietin protects the kidneys against ischemia reperfusion injury by activating hypoxia inducible factor-1alpha.

Imamura R, Moriyama T, Isaka Y, Namba Y, Ichimaru N, Takahara S, Okuyama A

Transplantation　Vol. 83　No. 10　p. 1371-1379　2007/05/27　Research paper (scientific journal)

Risk factors for malignancy in Japanese renal transplant recipients.

Imao T, Ichimaru N, Takahara S, Kokado Y, Okumi M, Imamura R, Namba Y, Isaka Y, Nonomura N, Okuyama A

Cancer　Vol. 109　No. 10　p. 2109-2115　2007/05/15　Research paper (scientific journal)

大阪大学における腎移植後妊娠症例の検討

阿部 豊文, 奥見 雅由, 今村 亮一, 市丸 直嗣, 猪阪 善隆, 高原 史郎

泌尿器科紀要　Vol. 53　No. 5　p. 359-359　2007/05

ラット腎阻血再灌流モデルにおける、Carbamylated erythropoietinによる腎保護効果の検討

今村 亮一, 市丸 直嗣, 奥山 明彦, 猪阪 善隆, 高原 史郎, 守山 敏樹

泌尿器科紀要　Vol. 53　No. 5　p. 359-359　2007/05

大阪大学における小児腎移植症例の検討

阿部 豊文, 吉岡 俊昭, 奥見 雅由, 今村 亮一, 市丸 直嗣, 奥山 明彦, 猪阪 善隆, 高原 史郎, 伊藤 喜一郎, 佐川 史郎, 園田 孝夫, 小角 幸人, 児島 康行

移植　Vol. 42　No. 2　p. 169-169　2007/04

DNAzymes as potential therapeutic molecules

Yoshitaka Isaka

Current Opinion in Molecular Therapeutics　Vol. 9　No. 2　p. 132-136　2007/04　Research paper (scientific journal)

Carbamylated erythropoietin protects the kidneys from ischemia-reperfusion injury without stimulating erythropoiesis.

Imamura R, Isaka Y, Ichimaru N, Takahara S, Okuyama A

Biochemical and biophysical research communications　Vol. 353　No. 3　p. 786-792　2007/02/16　Research paper (scientific journal)

SuperagonistCD28抗体によるドナー特異的移植免疫寛容誘導

猪阪 善隆, 高原 史郎, 水井 理之, 高畠 義嗣, 今井 圓裕, 東 治人, 李 小康

日本臨床免疫学会総会抄録集　Vol. 35　p. 61-61　2007

Gender difference in CKD-MBD among pre-dialysis patients (OVIDS-CKD)

Naohiko Fujii, Takayuki Hamano, Satoshi Mikami, Yasuyuki Nagasawa, Yoshitaka Isaka, Takahito Ito, Enyu Imai

NEPHROLOGY DIALYSIS TRANSPLANTATION　Vol. 22　p. 77-77　2007

Rise in FGF-23 precedes 1-84PTH and linear decline in calcitriol precedes rise in FGF-23 in non-diabetic predialysis patients

Takayuki Hamano, Kodo Tomida, Satoshi MIkami, Yasuyuki Nagasawa, Yoshitaka Isaka, Toshiki Moriyama, Masaru Horio, Takahito Ito, Enyu Imai

NEPHROLOGY DIALYSIS TRANSPLANTATION　Vol. 22　p. 218-218　2007

Electroporation-mediated gene therapy.

Isaka Y, Imai E

Expert Opin Drug Deliv.　Vol. 4　No. 5　p. 561-71　2007　Research paper (scientific journal)

Chemically modified siRNA prolonged RNA interference in renal disease.

Takabatake Y, Isaka Y, Mizui M, Kawachi H, Takahara S, Imai E

Biochem Biophys Res Commun.　Vol. 363　No. 2　p. 432-437　2007　Research paper (scientific journal)

Gene therapy targeting kidney diseases: Routes and vehicles

Yoshitaka Isaka

Clinical and Experimental Nephrology　Vol. 10　No. 4　p. 229-235　2006/12　Research paper (scientific journal)

Serum NTX is a practical marker for assessing antiresorptive therapy for glucocorticoid treated patients with chronic kidney disease

Hamano T, Fujii N, Nagasawa Y, Isaka Y, Moriyama T, Okada N, Imai E, Horio M, Ito T

Bone　Vol. 39　No. 5　p. 1067-1072　2006/11　Research paper (scientific journal)

慢性移植腎症におけるglycocalyx傷害の検討

張 道新, 猪阪 善隆, 今村 亮一, 市丸 直嗣, 大塚 愛二, 高原 史郎

Organ Biology　Vol. 13　No. 3　p. 347-347　2006/10

Carbamylated erythropoietinによる腎虚血再灌流傷害に対する組織保護効果

今村 亮一, 猪阪 善隆, 守山 敏樹, 市丸 直嗣, 張 道中, 高原 史郎, 奥山 明彦

Organ Biology　Vol. 13　No. 3　p. 379-379　2006/10

Oral risedronate is a successful treatment for bone loss in the long-term kidney transplant patients

Naohiko Fujii, Takayuki Hamano, Satoshi Mikami, Takah Ito ito, Yukito Kokado, Yoshitaka Isaka, Shiro Takahara, Enyu Imai

NEPHROLOGY DIALYSIS TRANSPLANTATION　Vol. 21　p. 527-527　2006/07　Research paper (scientific journal)

Urinary dipstick test is a significant determinant of serum 25-hydroxyvitamin D in CKD patients

Takayuki Hamano, Naohiko Fujii, Satoshi Mikami, Yasuyuki Nagasawa, Yoshitaka Isaka, Masaru Horio, Takah Ito ito, Enyu Imai

NEPHROLOGY DIALYSIS TRANSPLANTATION　Vol. 21　p. 132-133　2006/07　Research paper (scientific journal)

Stepwise increase in CACS and pulse pressure among pre-dialysis diabetic patients

Satoshi Mikami, Takayuki Hamano, Naohiko Fujii, Yasuyuki Nagasawa, Yoshitaka Isaka, Toshiki Moriyama, Masaru Horio, Takah Ito ito, Enyu Imai

NEPHROLOGY DIALYSIS TRANSPLANTATION　Vol. 21　p. 408-408　2006/07　Research paper (scientific journal)

ABO不適合腎移植における脾臓摘出の抗HLA抗体産生に対する影響の検討

難波 行臣, 佐田 正晴, 史 屹, 石黒 伸一, 今村 亮一, 市丸 直嗣, 猪阪 善隆, 永谷 憲歳, 丸屋 悦子, 赤座 達也, 佐治 博夫, 高原 史郎, 奥山 明彦

MHC: Major Histocompatibility Complex　Vol. 13　No. 1　p. 46-46　2006/05

腎移植患者の服薬コンプライアンス 免疫抑制剤を中心としたアンケート調査

角田 洋一, 矢澤 浩治, 細見 昌弘, 斉藤 純, 岸川 英史, 西村 憲二, 市川 靖二, 中川 勝弘, 客野 宮治, 阪口 勝彦, 吉岡 俊昭, 小角 幸人, 山口 誓司, 原 恒男, 児島 康行, 今村 亮一, 市丸 直嗣, 石黒 伸, 猪阪 善隆, 高原 史郎, 伊藤 喜一郎

今日の移植　Vol. 19　No. 3　p. 263-267　2006/05

腎移植後の固有腎癌に対する臨床的検討

石黒 伸, 今村 亮一, 難波 行臣, 市丸 直嗣, 奥山 明彦, 猪阪 善隆, 高原 史郎, 児島 康行, 河村 知史, 樋上 真由美

大阪透析研究会会誌　Vol. 24　No. 1　p. 119-119　2006/03

腎移植後の抗体関連型拒絶反応に対し,免疫グロブリン大量療法と血漿交換の併用が奏効した一例

石黒 伸, 今尾 哲也, 難波 行臣, 今村 亮一, 市丸 直嗣, 奥山 明彦, 猪阪 善隆, 高原 史郎, 京 昌弘

大阪透析研究会会誌　Vol. 24　No. 1　p. 119-119　2006/03

Erythropoietinによる虚血再灌流傷害に対する腎機能保護効果とその作用機序に関する検討

今村 亮一, 守山 敏樹, 石黒 伸, 史 屹, 難波 行臣, 市丸 直嗣, 猪阪 善隆, 高原 史郎, 奥山 明彦

日本泌尿器科学会雑誌　Vol. 97　No. 2　p. 276-276　2006/03

大阪大学におけるタクロリムスを主体とする免疫抑制方法施行時のprotocol biopsy病理組織所見と臨床結果の検討

難波 行臣, 京 昌弘, 石黒 伸, 今村 亮一, 市丸 直嗣, 猪阪 善隆, 小角 幸人, 高原 史郎, 奥山 明彦

日本泌尿器科学会雑誌　Vol. 97　No. 2　p. 414-414　2006/03

ABO-incompatible kidney transplantation with anti-CD20 monoclonal antibodies, intravenous immunoglobulin and plasmapheresis without splenectomy: A case report

Ryoichi Imamura, Shin Ishiguro, Yi Shi, Yukiomi Namba, Naotsugu Ichimaru, Yoshitaka Isaka, Shiro Takahara, Akihiko Okuyama

Xenotransplantation　Vol. 13　No. 2　p. 133-135　2006/03　Research paper (international conference proceedings)

Incidence of positive C4d deposition in long-term survival cases over 10 yr after renal transplantation.

Namba Y, Oka K, Moriyama T, Kyo M, Imamura R, Shi Y, Ichimaru N, Isaka Y, Takahara S, Okuyama A

Clinical transplantation　Vol. 20 Suppl 15　p. 20-25　2006　Research paper (scientific journal)

Transcription factor Ets-1 is essential for mesangial matrix remodeling.

Mizui M, Isaka Y, Takabatake Y, Sato Y, Kawachi H, Shimizu F, Takahara S, Ito T, Imai E

Kidney Int.　Vol. 70　No. 2　p. 298-305　2006　Research paper (scientific journal)

Targeting of interstitial cells using a simple gene-transfer strategy.

Fujii N, Isaka Y, Takabatake Y, Mizui M, Suzuki C, Takahara S, Ito T, Imai E

Nephrol Dial Transplant.　Vol. 21　No. 10　p. 2745-53　2006　Research paper (scientific journal)

既存抗体陽性生体腎移植術後に生じた抗体関連型拒絶反応に対して血漿交換および免疫グロブリン大量療法(IVIG)が奏効した1例

難波 行臣, 今尾 哲也, 石黒 伸, 今村 亮一, 市丸 直嗣, 猪阪 善隆, 京 昌弘, 小角 幸人, 高原 史郎, 奥山 明彦

腎移植・血管外科　Vol. 17　No. 1　p. 36-40　2005/11

Exploring RNA inteference as a therapeutic strategy for renal disease

Y. Takabatake, Y. Isaka, M. Mizui, H. Kawachi, F. Shimizu, T. Ito, M. Hori, E. Imai

Gene Therapy　Vol. 12　No. 12　p. 965-973　2005/06　Research paper (scientific journal)

EXPLORING RNA INTERFERENCE AS THERAPEUTIC STRATEGY FOR RENAL DISEASE

Enyu Imai, Yoshitsugu Takabatake, Yoshitaka Isaka, Masayuki Mizui, Naohiko Fujii, Takahito Ito, Enyu Imai

NEPHROLOGY　Vol. 10　p. A15-A15　2005/06

Electroporation-mediated HGF gene transfection protected the kidney against graft injury.

Isaka Y, Yamada K, Takabatake Y, Mizui M, Miura-Tsujie M, Ichimaru N, Yazawa K, Utsugi R, Okuyama A, Hori M, Imai E, Takahara S

Gene Ther.　Vol. 12　No. 10　p. 815-820　2005/05　Research paper (scientific journal)

Gene therapy for kidney transplantation

ISAKA Yoshitaka, IMAI Enyu

Jpn J Nephrol　Vol. 47　No. 2　p. 94-99　2005/02/25

Suppression of cyclosporine A nephrotoxicity in vivo by transforming growth factor β receptor-immunoglobulin G chimeric protein

Jing Xin, Toshio Homma, Taiji Matsusaka, Ji Ma, Yoshitaka Isaka, Enyu Imai, Iekuni Ichikawa

Transplantation　Vol. 77　No. 9　p. 1433-1442　2004/05/15　Research paper (scientific journal)

Local Actions of Endogenous Angiotensin II in Injured Glomeruli

Ji Ma, Taiji Matsusaka, Haichun Yang, Hiroshi Kawachi, Fujio Shimizu, Yoshitaka Isaka, Enyu Imai, Valentina Kon, Iekuni Ichikawa

Journal of the American Society of Nephrology　Vol. 15　No. 5　p. 1268-1276　2004/05　Research paper (scientific journal)

Gene therapy in renal diseases

E Imai, Y Takabatake, M Mizui, Y Isaka

KIDNEY INTERNATIONAL　Vol. 65　No. 5　p. 1551-1555　2004/05　Research paper (scientific journal)

ポストゲノム時代の腎臓病研究

今井 圓裕, 伊藤 孝仁, 猪阪 善隆

日本内科学会雑誌　Vol. 93　No. 4　p. 800-807　2004/04/10

Direct transfer of hepatocyte growth factor gene into kidney suppresses cyclosporin A nephrotoxicity in rats.

Yazawa K, Isaka Y, Takahara S, Imai E, Ichimaru N, Shi Y, Namba Y, Okuyama A

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association　Vol. 19　No. 4　p. 812-816　2004/04

Perspectives for gene therapy in renal diseases

Enyu Imai, Yoshitaka Isaka

Internal Medicine　Vol. 43　No. 2　p. 85-96　2004/02

DNAzyme for TGF-β suppressed extracellular matrix accumulation in experimental glomerulonephritis

Yoshitaka Isaka, Hiroyuki Nakamura, Masayuki Mizui, Yoshitsugu Takabatake, Masaru Horio, Hiroshi Kawachi, Fujio Shimizu, Enyu Imai, Masatsugu Hori

Kidney International　Vol. 66　No. 2　p. 586-590　2004/02　Research paper (scientific journal)

Expression and purification of untagged full-length HCV NS5B RNA-dependent RNA polymerase

Q. May Wang, Robert B. Johnson, Dayue Chen, Vincent J.-P. Lévêque, Jianxin Ren, Michaile A. Hockman, Kenji Abe, Tessho Hachisu, Yutaka Kondo, Yoshitaka Isaka, Akihiko Sato, Tamio Fujiwara

Protein Expression and Purification　Vol. 35　No. 2　p. 304-312　2004　Research paper (scientific journal)

Platelet-derived growth factor plays a critical role to convert bone marrow cells into glomerular mesangial-like cells

Akira Suzuki, Hirotsugu Iwatani, Takahito Ito, Enyu Imai, Masaru Okabe, Hiroyuki Nakamura, Yoshitaka Isaka, Masaya Yamato, Masatsugu Hori

Kidney International　Vol. 65　No. 1　p. 15-24　2004　Research paper (scientific journal)

Electroporation-mediated HGF gene transfer ameliorated cyclosporine nephrotoxicity.

Mizui M, Isaka Y, Takabatake Y, Mizuno S, Nakamura T, Ito T, Imai E, Hori M

Kidney Intl.　Vol. 65　p. 2041-2053　2004　Research paper (scientific journal)

Antisense oligonucleotides against thrombospondin-1 inhibit activation of tgf-beta in fibrotic renal disease in the rat in vivo.

Christoph Daniel, Yoshitugu Takabatake, Masayuki Mizui, Yoshitaka Isaka, Hiroshi Kawashi, Harald Rupprecht, Enyu Imai, Christian Hugo

The American journal of pathology　Vol. 163　No. 3　p. 1185-92　2003/09　Research paper (scientific journal)

Carbonic adsorbent AST-120 retards progression of renal failure by additive effect with ACEI and protein restriction diet

Enyu Imai, Masaru Takenaka, Yoshitaka Isaka, Toshiki Moriyama, Yoshitaka Akagi, Jyunji Kakuchi, Takashi Fujii, Takahito Ito, Masatsugu Hori, Masaru Horio, Tatsuya Syoji, Yoshiharu Tsubakihara

Clinical and Experimental Nephrology　Vol. 7　No. 2　p. 113-119　2003/06　Research paper (scientific journal)

Electroporation-mediated ex vivo gene transfer into graft not requiring injection pressure in orthotopic liver transplantation

Shogo Kobayashi, Keizo Dono, Shiro Takahara, Yoshitaka Isaka, Enyu Imai, Lu Zhenhui, Hiroaki Nagano, Kato Tomoaki, Koji Umeshita, Shoji Nakamori, Masato Sakon, Morito Monden

Journal of Gene Medicine　Vol. 5　No. 6　p. 510-517　2003/06　Research paper (scientific journal)

Gene transfer into the liver by plasmid injection into the portal vein combined with electroporation

Shogo Kobayashi, Keizo Dono, Toshiyuki Tanaka, Shiro Takahara, Yoshitaka Isaka, Enyu Imai, Hiroaki Nagano, Kato Tomoaki, Koji Umeshita, Shoji Nakamori, Masato Sakon, Morito Monden

Journal of Gene Medicine　Vol. 5　No. 3　p. 201-208　2003/03　Research paper (scientific journal)

In vivo gene transfer of hepatocyte growth factor to skeletal muscle prevents changes in rat kidneys after 5/6 nephrectomy.

Tanaka T, Ichimaru N, Takahara S, Yazawa K, Hatori M, Suzuki K, Isaka Y, Moriyama T, Imai E, Azuma H, Nakamura T, Okuyama A, Yamanaka H

American journal of transplantation　Vol. 2　No. 9　p. 828-836　2002/10

検査データを考える 血尿-蛋白尿との関連

水井 理之, 猪阪 善隆, 今井 圓裕

検査と技術　Vol. 30　No. 3　p. 293-297　2002/03/01

エレクトロポレーション法を用いた移植腎への遺伝子導入

矢澤 浩治, 高原 史郎, 田中 俊之, 花房 徹, 史 屹, 奥山 明彦, 猪阪 善隆, 今井 圓裕, 東 治人, 擣木 立

日本泌尿器科学会雑誌　Vol. 93　No. 2　p. 199-199　2002

Introduction of DNA enzyme for Egr-1 into tubulointerstitial fibroblasts by electroporation reduced interstitial α-smooth muscle actin expression and fibrosis in unilateral ureteral obstruction (UUO) rats

H. Nakamura, Y. Isaka, M. Tsujie, H. D. Rupprecht, Y. Akagi, N. Ueda, E. Imai, M. Hori

Gene Therapy　Vol. 9　No. 8　p. 495-502　2002　Research paper (scientific journal)

Gene electrotransfer: Potential for gene therapy of renal diseases

Enyu Imai, Yoshitaka Isaka

Kidney International　Vol. 61　No. 1　p. S37-S41　2002　Research paper (international conference proceedings)

Targeting growth factors to the kidney: Myth or reality?

Enyu Imai, Yoshitaka Isaka

Current Opinion in Nephrology and Hypertension　Vol. 11　No. 1　p. 49-57　2002

Future strategy: Gene therapy for diabetic nephropathy

Yoshitaka Isaka, Enyu Imai

Contributions to Nephrology　Vol. 134　p. 127-132　2001　Research paper (scientific journal)

Prolonged transgene expression in glomeruli using an EBV replicon vector system combined with HVJ liposomes

M. Tsujie, Y. Isaka, H. Nakamura, Y. Kaneda, E. Imai, M. Hori

Kidney International　Vol. 59　No. 4　p. 1390-1396　2001　Research paper (scientific journal)

Electroporation-mediated gene transfer that targets glomeruli

M. Tsujie, Y. Isaka, H. Nakamura, E. Imai, M. Hori

Journal of the American Society of Nephrology　Vol. 12　No. 5　p. 949-954　2001　Research paper (scientific journal)

Electroporation-mediated PDGF receptor-IgG chimera gene transfer ameliorates experimental glomerulonephritis

Hiroyuki Nakamura, Yoshitaka Isaka, Michiko Tsujie, Yoshitaka Akagi, Tetsuo Sudo, Noriko Ohno, Enyu Imai, Masatsugu Hori

Kidney International　Vol. 59　No. 6　p. 2134-2145　2001　Research paper (scientific journal)

腎疾患の新しい治療戦略 (特集 腎疾患の分子医学--基礎と臨床)

今井 圓裕, 猪阪 善隆, 辻江 道子

現代医療　Vol. 32　No. 3　p. 832-836　2000/03

Gene transfer targeting interstitial fibroblasts by the artificial viral envelope-type hemagglutinating virus of Japan liposome method

Michiko Tsujie, Yoshitaka Isaka, Yutaka Ando, Yoshitaka Akagi, Yasufumi Kaneda, Naohiko Ueda, Enyu Imai, Masatsugu Hori

Kidney International　Vol. 57　No. 5　p. 1973-1980　2000　Research paper (scientific journal)

Transforming growth factor-β1 antisense oligodeoxynucleotides block interstitial fibrosis in unilateral ureteral obstruction

Y. Isaka, M. Tsujie, Y. Ando, H. Nakamura, Y. Kaneda, E. Imai, M. Hori

Kidney International　Vol. 58　No. 5　p. 1885-1892　2000　Research paper (scientific journal)

Small amino acid changes in the V3 loop of human immunodeficiency virus type 2 determines the coreceptor usage for CXCR4 and CCr5

Yoshitaka Isaka, Akihiko Sato, Shigeru Miki, Shinobu Kawauchi, Hitoshi Sakaida, Toshiyuki Hori, Takashi Uchiyama, Akio Adachi, Masanori Hayami, Tamio Fujiwara, Osamu Yoshie

Virology　Vol. 264　No. 1　p. 237-243　1999/11/10　Research paper (scientific journal)

Enhanced interstitial expression of caldesmon in IgA nephropathy and its suppression by glucocorticoid-heparin therapy

Y Ando, T Moriyama, K Oka, K Takatsuji, M Miyazaki, Y Akagi, N Kawada, Y Isaka, M Izumi, K Yokoyama, A Yamauchi, M Horio, A Ando, N Ueda, K Sobue, E Imai, M Hori

NEPHROLOGY DIALYSIS TRANSPLANTATION　Vol. 14　No. 6　p. 1408-1417　1999/06　Research paper (scientific journal)

Cytokines and glomerulosclerosis

Y. Isaka, Y. Akagi, Y. Ando, M. Tsujie, Enyu Imai

Nephrology Dialysis Transplantation　Vol. 14　No. 1　p. 30-32　1999　Research paper (international conference proceedings)

Glowing podocytes in living mouse: Transgenic mouse carrying a podocyte- specific promoter

Enyu Imai, Yoshitaka Akagi, Yoshitaka Isaka, Masahito Ikawa, Masaru Takenaka, Masatsugu Hori, Masaru Okabe

Experimental Nephrology　Vol. 7　No. 1　p. 63-66　1999/01　Research paper (international conference proceedings)

Gene therapy by transforming growth factor-β receptor-IgG Fc chimera suppressed extracellular matrix accumulation in experimental glomerulonephritis

Yoshitaka Isaka, Yoshitaka Akagi, Yutaka Ando, Michiko Tsujie, Tetsuo Sudo, Noriko Ohno, Wayne A. Border, Nancy A. Noble, Yasufumi Kaneda, Masatsugu Hori, Enyu Imai

Kidney International　Vol. 55　No. 2　p. 465-475　1999　Research paper (scientific journal)

Application of gene therapy to kidney diseases

Y. Isaka

Clinical and Experimental Nephrology　Vol. 3　No. 3　p. 147-153　1999

New paradigm of gene therapy: Skeletal-muscle-targeting gene therapy for kidney disease

Enyu Imai, Yoshitaka Isaka

Nephron　Vol. 83　No. 4　p. 296-300　1999

T-trophic human immunodeficiency virus type 1 (HIV-1)-derived V3 loop peptides directly bind to CXCR-4 and inhibit T-tropic HIV-1 infection

Hitoshi Sakaida, Toshiyuki Hori, Akihito Yonezawa, Akihiko Sato, Yoshitaka Isaka, Osamu Yoshie, Toshio Hattori, Takashi Uchiyama

Journal of Virology　Vol. 72　No. 12　p. 9763-9770　1998/12　Research paper (scientific journal)

S-1153 inhibits replication of known drug-resistant strains of human immunodeficiency virus type 1

Tamio Fujiwara, Akihiko Sato, Mohamed El-Farrash, Shigeru Miki, Kenji Abe, Yoshitaka Isaka, Makoto Kodama, Yaming Wu, Lan Bo Chen, Hiroshi Harada, Hirohiko Sugimoto, Masakazu Hatanaka, Yorio Hinuma

Antimicrobial Agents and Chemotherapy　Vol. 42　No. 6　p. 1340-1345　1998/06　Research paper (scientific journal)

Enhanced glomerular expression of caldesmon in IgA nephropathy and its suppression by glucocorticoid-heparin therapy

Y Ando, T Moriyama, M Miyazaki, Y Akagi, N Kawada, Y Isaka, M Izumi, K Yokoyama, A Yamauchi, M Horio, A Ando, N Ueda, K Sobue, E Imai, M Hori

NEPHROLOGY DIALYSIS TRANSPLANTATION　Vol. 13　No. 5　p. 1168-1175　1998/05　Research paper (scientific journal)

Determination of uric acid in scalp hair for non-invasive evaluation of uricemic controls in hyperuricemia

Kunio Kobayashi, Yasuhide Morioka, Yoshitaka Isaka, Tatsuo Tozawa

Biological and Pharmaceutical Bulletin　Vol. 21　No. 4　p. 398-400　1998　Research paper (scientific journal)

Gene transfer and kidney disease

Enyu Imai, Yoshitaka Isaka, Yoshitaka Akagi, Yasufumi Kaneda, Masatsugu Hori

Journal of Nephrology　Vol. 11　No. 1　p. 16-19　1998/01

Construction of the chimeric reverse transcriptase of simian immunodeficiency virus sensitive to nonnucleoside reverse transcriptase inhibitor

Yoshitaka Isaka, Akihiko Sato, Shinobu Kawauchi, Akemi Suyama, Shigeru Miki, Masanori Hayami, Tamio Fujiwara

Microbiology and Immunology　Vol. 42　No. 3　p. 195-202　1998　Research paper (scientific journal)

The HVJ liposome method

Yoshitaka Isaka, Yoshitaka Akagi, Yasufumi Kaneda, Enyu Imai

Experimental Nephrology　Vol. 6　No. 2　p. 144-147　1998　Research paper (international conference proceedings)

Strategies of gene transfer to the kidney

Enyu Imai, Yoshitaka Isaka

Kidney International　Vol. 53　No. 2　p. 264-272　1998

Towards gene therapy for renal diseases

E. Imai, Y. Akagi, Y. Isaka

Nephrologie　Vol. 19　No. 7　p. 397-402　1998　Research paper (scientific journal)

Involvement of MAP kinase phosphatase-1 in mesangial cell growth regulation

T Moriyama, C Xia, A Miyai, Y Akagi, Y Isaka, T Kaneko, N Kawada, N Ueda, A Yamauchi, M Horio, A Ando, E Imai, M Hori

NEPHROLOGY　Vol. 3　No. 5　p. 443-453　1997/10　Research paper (scientific journal)

New therapeutic strategies of molecular intervention in glomerulonephritis

E Imai, Y Isaka, Y Akagi, Y Ando, M Arai, T Kaneko, M Takenaka, T Moriyama, A Yamauchi, M Horio, A Ando, Y Crita, N Ueda

NEPHROLOGY　Vol. 3　p. S755-S757　1997/10　Research paper (scientific journal)

Transcriptional activation of a hybrid promoter composed of cytomegalovirus enhancer and beta-actin/beta-globin gene in glomerular epithelial cells in vivo.

Akagi Y, Isaka Y, Akagi A, Ikawa M, Takenaka M, Moriyama T, Yamauchi A, Horio M, Ueda N, Okabe M, Imai E

Kidney Int.　Vol. 51(4):1265-9　1997/04　Research paper (scientific journal)

Gene transfer into the glomerulus by the hemagglutinating virus of Japan-liposome method

Enyu Imai, Yoshitaka Isaka, Yoshitaka Akagi, Yasufumi Kaneda

Experimental Nephrology　Vol. 5　No. 2　p. 112-117　1997/03

Molecular intervention with antisense oligodeoxynucleotides (ODNs) in Nephrology

E. Imai, Y. Akagi, Y. Isaka

Nephrology Dialysis Transplantation　Vol. 12　No. 11　p. 2213-2215　1997　Research paper (scientific journal)

Application of gene therapy to diabetic nephropathy

Y. Isaka, Y. Akagi, Y. Ando, E. Imai

Kidney International, Supplement　Vol. 51　No. 60　p. S-100-S-103　1997　Research paper (international conference proceedings)

Evidence for direct association of Vpr and matrix protein p17 within the HIV-1 virion

Akihiko Sato, Jun Yoshimoto, Yoshitaka Isaka, Shigeru Miki, Akemi Suyama, Akio Adachi, Masanori Hayami, Tamio Fujiwara, Osamu Yoshie

Virology　Vol. 220　No. 1　p. 208-212　1996/06/01　Research paper (scientific journal)

Inhibition of TGF-β1 expression by antisense oligonucleotides suppressed extracellular matrix accumulation in experimental glomerulonephritis

Yoshitaka Akagi, Yoshitaka Isaka, Makoto Arai, Tetsuya Kaneko, Masaru Takenaka, Toshiki Moriyama, Yasufumi Kaneda, Akio Ando, Yoshimasa Orita, Takenobu Kamada, Naohiko Ueda, Enyu Imai

Kidney International　Vol. 50　No. 1　p. 148-155　1996　Research paper (scientific journal)

Gene therapy by skeletal muscle expression of decorin prevents fibrotic disease in rat kidney

Yoshitaka Isaka, Douglas K. Brees, Kazuko Ikegaya, Yasufumi Kaneda, Enyu Imai, Nancy A. Noble, Wayne A. Border

Nature Medicine　Vol. 2　No. 4　p. 418-423　1996　Research paper (scientific journal)

Molecular biological intervention

Yoshitaka Isaka, Enyu Imai

Seminars in Nephrology　Vol. 16　No. 6　p. 591-598　1996

Application of antisense oligodeoxynucleotides (ODNs) for the intervention of kidney disease: Antisense ODNs for transforming growth factor-β- suppressed glomerulosclerosis in experimental glomerulonephritis

Enyu Imai, Yoshitaka Isaka, Yoshitaka Akagi, Makoto Arai, Toshiki Moriyama, Masaru Takenaka, Tetsuya Kaneko, Masaru Horio, Akio Ando, Yoshimasa Orita, Yasufumi Kaneda, Naohiko Ueda, Takenobu Kamada

Contributions to Nephrology　Vol. 118　p. 86-93　1996

Targeting of Chrolamphenicol Acetyltransferase to Human Immunodeficiency Virus Particles via Vpr and Vpx

Akihiko Sato, Yoshitaka Isaka, Makoto Kodama, Jun Yoshimoto, Shinobu Kawauchi, Osamu Yoshie, Tamio Fujiwara, Takeo Kuwata

MICROBIOLOGY and IMMUNOLOGY　Vol. 39　No. 12　p. 1015-1019　1995　Research paper (scientific journal)

In vivo transfection of genes for ranin and angiotensinogen into the glomerular cells induced phenotypic change of the mesangial cells and glomerular sclerosis

ARAI M, WADA A, ISAKA Y, AKAGI Y, SUGIURA T, MIYAZAKI M, MORIYAMA T, KANEDA Y, IMAI E

Biochemical and Biophysical Research Communication　Vol. 206　No. 2　p. 525-532　1995

Isolation of mitochondrial cyclophilin from bovine heart

Toru Inoue, Yukuo Yoshida, Yoshitaka Isaka, Kunio Tagawa

Biochemical and Biophysical Research Communications　Vol. 190　No. 3　p. 857-863　1993/02/15　Research paper (scientific journal)

Glomerulosclerosis induced by in vivo transfection of transforming growth factor-β or platelet-derived growth factor gene into the rat kidney

Yoshitaka Isaka, Yoshihiro Fujiwara, Naohiko Ueda, Yasufumi Kaneda, Takenobu Kamada, Enyu Imai

Journal of Clinical Investigation　Vol. 92　No. 6　p. 2597-2601　1993　Research paper (scientific journal)

Modified plasma clearance technique using nonradioactive iothalamate for measuring GFR

Yoshitaka Isaka, Yoshihiro Fujiwara, Shigeo Yamamoto, Satoshi Ochi, Sunghyo Shin, Toru Inoue, Kunio Tagawa, Takenobu Kamada, Naohiko Ueda

Kidney International　Vol. 42　No. 4　p. 1006-1011　1992　Research paper (scientific journal)