顔写真

PHOTO

Ueda Masahiro
上田 昌宏
Ueda Masahiro
上田 昌宏
Graduate School of Frontier Biosciences Department of Frontier Biosciences, Professor

keyword Single molecule tracking based screening,cellular slime mold,chemotaxis,self-organization,signal transduction,Single Molecule Biology

Research History 17

  1. 2021/10 - Present
    科学技術振興機構・戦略的創造研究推進事業 JST-CREST 「細胞内現象の時空間ダイナミクス」領域 研究代表者

  2. 2016/04 - Present
    Osaka University Graduate School of Frontier Biosciences

  3. 2012/04 - Present
    Osaka University Graduate School of Science

  4. 2018/04 - 2025/03
    RIKEN BDR

  5. 2015/10 - 2021/03
    革新的先端研究開発支援事業 AMED-CREST 「画期的医薬品等の創出をめざす脂質の生理活性と機能の解明」領域 研究代表者

  6. 2013/10 - 2018/03
    JST/AMED 先端計測分析技術機器開発プログラム 研究代表者

  7. 2011/04 - 2018/03
    RIKEN Quantitative Biology Center (QBiC)

  8. 2007/10 - 2013/03
    科学技術振興機構・戦略的創造研究推進事業 「生命システムの動作原理と基盤技術」領域 CREST研究代表者

  9. 2007/10 - 2012/03
    Osaka University

  10. 2006/08 - 2007/09
    大阪大学大学院 生命機能研究科 ゆらぎプロジェクト 特任教授

  11. 2003/10 - 2006/08
    リーディングプロジェクト・バイオナノプロセス 産官学連携研究員

  12. 2000/10 - 2003/09
    科学技術振興事業団 さきがけ研究 研究員

  13. 1999/04 - 2000/09
    Osaka University Graduate School of Medicine

  14. 1998/10 - 1999/03
    Osaka University Faculty of Medicine

  15. 1996/06 - 1998/06
    ドイツ・ミュンヘン大学 日本学術振興会 海外特別研究員

  16. 1995/04 - 1996/06
    Osaka University School of Science

  17. 1993/04 - 1995/03
    Osaka University

Education 3

  1. 大阪大学理学研究科生理学専攻博士後期課程

    1991/04 - 1995/03

  2. 大阪大学理学研究科生理学専攻博士前期課程

    1989/04 - 1991/03

  3. Osaka University School of Science

    1985/04 - 1989/03

Committee Memberships 6

  1. Forefront Research Center (FRC) Vice Director

    2022/04 - Present

  2. 大阪大学・理化学研究所科学技術融合研究センター 副センター長

    2022/04 - Present

  3. Science Council of Japan associate member

    2014/10 - Present

  4. Japanese Society for the Study of Cellular slime Molds (JSCSM) President Academic society

    2021/01 - 2024/12

  5. The Biophysical Society of Japan Editor-in-chief Academic society

    2022/01 - 2023/12

  6. 大阪大学・バイオ関連多目的研究施設 施設長

    2013/04 - 2015/03

Professional Memberships 4

  1. Japanese Society for the Study of Cellular Slime Molds

  2. THE JAPANESE SOCIETY OF MICROSCOPY

  3. JAPAN SOCIETY FOR CELL BIOLOGY

  4. THE BIOPHYSICAL SOCIETY OF JAPAN

Research Areas 3

  1. Nanotechnology/Materials / Nanobioscience /

  2. Life sciences / Cell biology /

  3. Life sciences / Biophysics /

Papers 99

  1. Excitable Ras dynamics-based screens reveal RasGEFX is required for macropinocytosis and random cell migration.

    Koji Iwamoto, Satomi Matsuoka, Masahiro Ueda

    Nature communications Vol. 16 No. 1 p. 117-117 2025/01/02 Research paper (scientific journal)

  2. Single molecule tracking based drug screening.

    Daisuke Watanabe, Michio Hiroshima, Masato Yasui, Masahiro Ueda

    Nature communications Vol. 15 No. 1 p. 8975-8975 2024/10/17 Research paper (scientific journal)

  3. Left-right Myosin-Is, Myosin1C, and Myosin1D exhibit distinct single molecule behaviors on the plasma membrane of Drosophila macrophages.

    Sosuke Utsunomiya, Kazutoshi Takebayashi, Asuka Yamaguchi, Takeshi Sasamura, Mikiko Inaki, Masahiro Ueda, Kenji Matsuno

    Genes to cells : devoted to molecular & cellular mechanisms Vol. 29 No. 5 p. 380-396 2024/05 Research paper (scientific journal)

  4. Spontaneous signal generation by an excitable system for cell migration

    Satomi Matsuoka, Koji Iwamoto, Da Young Shin, Masahiro Ueda

    Frontiers in Cell and Developmental Biology Vol. 12 2024/02/28 Research paper (scientific journal)

    Publisher: Frontiers Media SA
  5. Cholesterol suppresses spontaneous activation of EGFR-mediated signal transduction.

    Miri Takayama, Sakura Maeda, Daisuke Watanabe, Kazutoshi Takebayashi, Michio Hiroshima, Masahiro Ueda

    Biochemical and biophysical research communications Vol. 704 p. 149673-149673 2024/02/12 Research paper (scientific journal)

  6. Application of single-molecule analysis to singularity phenomenon of cells.

    Michio Hiroshima, Hiroko Bannai, Gen Matsumoto, Masahiro Ueda

    Biophysics and physicobiology Vol. 21 No. Supplemental 2024 Research paper (scientific journal)

  7. A dynamic partitioning mechanism polarizes membrane protein distribution.

    Tatsat Banerjee, Satomi Matsuoka, Debojyoti Biswas, Yuchuan Miao, Dhiman Sankar Pal, Yoichiro Kamimura, Masahiro Ueda, Peter N Devreotes, Pablo A Iglesias

    Nature communications Vol. 14 No. 1 p. 7909-7909 2023/11/30 Research paper (scientific journal)

  8. Field model for multistate lateral diffusion of various transmembrane proteins observed in living Dictyostelium cells.

    Kazutoshi Takebayashi, Yoichiro Kamimura, Masahiro Ueda

    Journal of cell science Vol. 136 No. 4 2023/02/15 Research paper (scientific journal)

  9. Sphingomyelin metabolism underlies Ras excitability for efficient cell migration and chemotaxis

    Da Young Shin, Hiroaki Takagi, Michio Hiroshima, Satomi Matsuoka, Masahiro Ueda

    Cell Structure and Function Vol. 48 No. 2 p. 145-160 2023 Research paper (scientific journal)

    Publisher: Japan Society for Cell Biology
  10. Heterotrimeric Gq proteins act as a switch for GRK5/6 selectivity underlying β-arrestin transducer bias.

    Kouki Kawakami, Masataka Yanagawa, Suzune Hiratsuka, Misaki Yoshida, Yuki Ono, Michio Hiroshima, Masahiro Ueda, Junken Aoki, Yasushi Sako, Asuka Inoue

    Nature communications Vol. 13 No. 1 p. 487-487 2022/01/25 Research paper (scientific journal)

  11. A sub-population of Dictyostelium discoideum cells shows extremely high sensitivity to cAMP for directional migration.

    Daisuke Ohtsuka, Nobutoshi Ota, Satoshi Amaya, Satomi Matsuoka, Yo Tanaka, Masahiro Ueda

    Biochemical and biophysical research communications Vol. 554 p. 131-137 2021/05/21 Research paper (scientific journal)

  12. Different Heterotrimeric G Protein Dynamics for Wide-Range Chemotaxis in Eukaryotic Cells.

    Yoichiro Kamimura, Masahiro Ueda

    Frontiers in cell and developmental biology Vol. 9 p. 724797-724797 2021 Research paper (scientific journal)

  13. Single-molecule imaging of PI(4,5)P2 and PTEN in vitro reveals a positive feedback mechanism for PTEN membrane binding.

    Daisuke Yoshioka, Seiya Fukushima, Hiroyasu Koteishi, Daichi Okuno, Toru Ide, Satomi Matsuoka, Masahiro Ueda

    Communications biology Vol. 3 No. 1 p. 92-92 2020/02/28 Research paper (scientific journal)

  14. Excitable dynamics of Ras triggers spontaneous symmetry breaking of PIP3 signaling in motile cells.

    Seiya Fukushima, Satomi Matsuoka, Masahiro Ueda

    Journal of cell science Vol. 132 No. 5 2019/03/04

  15. Collective cell migration of Dictyostelium without cAMP oscillations at multicellular stages

    Hashimura, H, Morimoto, Y. V, Yasui, M, Ueda, M

    Vol. 2 2019/01 Research paper (scientific journal)

  16. Chemoattractant receptors activate, recruit and capture G proteins for wide range chemotaxis.

    Yukihiro Miyanaga, Yoichiro Kamimura, Hidekazu Kuwayama, Peter N Devreotes, Masahiro Ueda

    Biochemical and biophysical research communications Vol. 507 No. 1-4 p. 304-310 2018/12/09 Research paper (scientific journal)

    Publisher: ACADEMIC PRESS INC ELSEVIER SCIENCE
  17. Parallel signaling pathways regulate excitable dynamics differently to mediate pseudopod formation during eukaryotic chemotaxis.

    Yuki Tanabe, Yoichiro Kamimura, Masahiro Ueda

    Journal of cell science Vol. 131 No. 23 2018/12/05

  18. Structural basis of Gip1 for cytosolic sequestration of G protein in wide-range chemotaxis.

    Takero Miyagawa, Hiroyasu Koteishi, Yoichiro Kamimura, Yukihiro Miyanaga, Kohei Takeshita, Atsushi Nakagawa, Masahiro Ueda

    Nature communications Vol. 9 No. 1 p. 4635-4635 2018/11/06

  19. Mutual inhibition between PTEN and PIP3 generates bistability for polarity in motile cells.

    Satomi Matsuoka, Masahiro Ueda

    Nature communications Vol. 9 No. 1 p. 4481-4481 2018/10/26 Research paper (scientific journal)

  20. Single-molecule diffusion-based estimation of ligand effects on G protein-coupled receptors.

    Masataka Yanagawa, Michio Hiroshima, Yuichi Togashi, Mitsuhiro Abe, Takahiro Yamashita, Yoshinori Shichida, Masayuki Murata, Masahiro Ueda, Yasushi Sako

    Science signaling Vol. 11 No. 548 2018/09/18 Research paper (scientific journal)

  21. Automated single-molecule imaging in living cells.

    Masato Yasui, Michio Hiroshima, Jun Kozuka, Yasushi Sako, Masahiro Ueda

    Nature communications Vol. 9 No. 1 p. 3061-3061 2018/08/03 Research paper (scientific journal)

  22. Transient acceleration of epidermal growth factor receptor dynamics produces higher order signaling clusters

    Hiroshima M, Pack C.G, Kaizu K, Takahashi K, Ueda M, Sako Y

    Journal of Molecular Biology 2018/04 Research paper (scientific journal)

  23. Heterotrimeric G-protein shuttling via Gip1 extends the dynamic range of eukaryotic chemotaxis

    Yoichiro Kamimura, Yukihiro Miyanaga, Masahiro Ueda

    PNAS Vol. 113 No. 16 p. 4356-4361 2016/04 Research paper (scientific journal)

  24. Integrin LFA-1 regulates cell adhesion via transient clutch formation

    Munenori Ishibashi, Yukihiro Miyanaga, Satomi Matsuoka, Jun Kozuka, Yuichi Togashi, Tatsuo Kinashi, Masahiro Ueda

    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS Vol. 464 No. 2 p. 459-466 2015/08 Research paper (scientific journal)

  25. Compact Halo-Ligand-Conjugated Quantum Dots for Multicolored Single-Molecule Imaging of Overcrowding GPCR Proteins on Cell Membranes

    Akihito Komatsuzaki, Tatsuya Ohyanagi, Yoshikazu Tsukasaki, Yukihiro Miyanaga, Masahiro Ueda, Takashi Jin

    SMALL Vol. 11 No. 12 p. 1396-1401 2015/03 Research paper (scientific journal)

  26. PTEN Hopping on the Cell Membrane Is Regulated via a Positively-Charged C2 Domain

    Masato Yasui, Satomi Matsuoka, Masahiro Ueda

    PLOS COMPUTATIONAL BIOLOGY Vol. 10 No. 9 2014/09 Research paper (scientific journal)

  27. Nucleocytoplasmic Shuttling of a GATA Transcription Factor Functions as a Development Timer

    Huaqing Cai, Mariko Katoh-Kurasawa, Tetsuya Muramoto, Balaji Santhanam, Yu Long, Lei Li, Masahiro Ueda, Pablo A. Iglesias, Gad Shaulsky, Peter N. Devreotes

    SCIENCE Vol. 343 No. 6177 p. 1329-+ 2014/03 Research paper (scientific journal)

  28. Excitable Signal Transduction Induces Both Spontaneous and Directional Cell Asymmetries in the Phosphatidylinositol Lipid Signaling System for Eukaryotic Chemotaxis

    Masatoshi Nishikawa, Marcel Horning, Masahiro Ueda, Tatsuo Shibata

    BIOPHYSICAL JOURNAL Vol. 106 No. 3 p. 723-734 2014/02 Research paper (scientific journal)

  29. TAG-1-assisted progenitor elongation streamlines nuclear migration to optimize subapical crowding

    Mayumi Okamoto, Takashi Namba, Tomoyasu Shinoda, Takefumi Kondo, Tadashi Watanabe, Yasuhiro Inoue, Kosei Takeuchi, Yukiko Enomoto, Kumiko Ota, Kanako Oda, Yoshino Wada, Ken Sagou, Kanako Saito, Akira Sakakibara, Ayano Kawaguchi, Kazunori Nakajima, Taiji Adachi, Toshihiko Fujimori, Masahiro Ueda, Shigeo Hayashi, Kozo Kaibuchi, Takaki Miyata

    NATURE NEUROSCIENCE Vol. 16 No. 11 p. 1556-1566 2013/11 Research paper (scientific journal)

  30. Intracellular Encoding of Spatiotemporal Guidance Cues in a Self-Organizing Signaling System for Chemotaxis in Dictyostelium Cells

    Tatsuo Shibata, Masatoshi Nishikawa, Satomi Matsuoka, Masahiro Ueda

    BIOPHYSICAL JOURNAL Vol. 105 No. 9 p. 2199-2209 2013/11 Research paper (scientific journal)

  31. Asymmetric PTEN Distribution Regulated by Spatial Heterogeneity in Membrane-Binding State Transitions

    Matsuoka S, Shibata T, Ueda M

    Plos Computational Biology Vol. 9 No. 1 2013

  32. Asymmetric PTEN Distribution Regulated by Spatial Heterogeneity in Membrane-Binding State Transitions

    Satomi Matsuoka, Tatsuo Shibata, Masahiro Ueda

    PLoS Computational Biology Vol. 9 No. 1 2013/01 Research paper (scientific journal)

  33. Modeling the self-organized phosphatidylinositol lipid signaling system in chemotactic cells using quantitative image analysis

    Tatsuo Shibata, Masatoshi Nishikawa, Satomi Matsuoka, Masahiro Ueda

    JOURNAL OF CELL SCIENCE Vol. 125 No. 21 p. 5138-5150 2012/11 Research paper (scientific journal)

  34. Talin couples the actomyosin cortex to the plasma membrane during rear retraction and cytokinesis

    Masatsune Tsujioka, Shigehiko Yumura, Kei Inouye, Hitesh Patel, Masahiro Ueda, Shigenobu Yonemura

    PNAS Vol. 109 No. 32 p. 12992-12997 2012/08 Research paper (scientific journal)

  35. Non-Brownian dynamics and strategy of amoeboid cell locomotion

    Shin I. Nishimura, Masahiro Ueda, Masaki Sasai

    PHYSICAL REVIEW E Vol. 85 No. 4 2012/04 Research paper (scientific journal)

  36. Self-organization of the phosphatidylinositol lipids signaling system for random cell migration

    Yoshiyuki Arai, Tatsuo Shibata, Satomi Matsuoka, Masayuki J. Sato, Toshio Yanagida, Masahiro Ueda

    PNAS Vol. 107 No. 27 p. 12399-12404 2010/07 Research paper (scientific journal)

  37. Statistical Analysis of Lateral Diffusion and Multistate Kinetics in Single-Molecule Imaging

    Satomi Matsuoka, Tatsuo Shibata, Masahiro Ueda

    BIOPHYSICAL JOURNAL Vol. 97 No. 4 p. 1115-1124 2009/08 Research paper (scientific journal)

  38. Switching direction in electric-signal-induced cell migration by cyclic guanosine monophosphate and phosphatidylinositol signaling

    Masayuki J. Sato, Hidekazu Kuwayama, Wouter N. van Egmond, Airi L. K. Takayama, Hiroaki Takagi, Peter J. M. van Haastert, Toshio Yanagida, Masahiro Ueda

    PNAS Vol. 106 No. 16 p. 6667-6672 2009/04 Research paper (scientific journal)

  39. Cortical Factor Feedback Model for Cellular Locomotion and Cytofission

    Shin I. Nishimura, Masahiro Ueda, Masaki Sasai

    PLOS COMPUTATIONAL BIOLOGY Vol. 5 No. 3 2009/03 Research paper (scientific journal)

  40. Signal transduction across the plasma membrane

    Ueda M, Shibata T, Sako Y

    Single Molecule Dynamics in Life Science p. 99-116 2009

  41. Multiple Mechanisms for Accumulation of Myosin II Filaments at the Equator During Cytokinesis

    Shigehiko Yumura, Masahiro Ueda, Yasushi Sako, Toshiko Kitanishi-Yumura, Toshio Yanagida

    TRAFFIC Vol. 9 No. 12 p. 2089-2099 2008/12 Research paper (scientific journal)

  42. Functional Analysis of Spontaneous Cell Movement under Different Physiological Conditions

    Hiroaki Takagi, Masayuki J. Sato, Toshio Yanagida, Masahiro Ueda

    PLOS ONE Vol. 3 No. 7 2008/07 Research paper (scientific journal)

  43. Noise generation, amplification and propagation in chemotactic signaling systems of living cells

    Tatsuo Shibata, Masahiro Ueda

    BIOSYSTEMS Vol. 93 No. 1-2 p. 126-132 2008/07 Research paper (scientific journal)

  44. Stochastic signal processing and transduction in chemotactic response of eukaryotic cells

    Masahiro Ueda, Tatsuo Shibata

    BIOPHYSICAL JOURNAL Vol. 93 No. 1 p. 11-20 2007/07 Research paper (scientific journal)

  45. Input-output relationship in galvanotactic response of Dictyostelium cells

    Masayuki J. Sato, Michihito Ueda, Hiroaki Takagi, Tomonobu M. Watanabe, Toshio Yanagida, Masahiro Ueda

    BIOSYSTEMS Vol. 88 No. 3 p. 261-272 2007/04 Research paper (scientific journal)

  46. Stochastic signal inputs for chemotactic response in Dictyostelium cells revealed by single molecule imaging techniques

    Yukihiro Miyanaga, Satomi Matsuoka, Toshio Yanagida, Masahiro Ueda

    BIOSYSTEMS Vol. 88 No. 3 p. 251-260 2007/04 Research paper (scientific journal)

  47. Brownian motion, fluctuation and life

    Toshio Yanagida, Masahiro Ueda, Tsutomu Murata, Seiji Esaki, Yoshiharu Ishii

    BIOSYSTEMS Vol. 88 No. 3 p. 228-242 2007/04 Research paper (scientific journal)

  48. Single-molecule analysis of chemoattractant-stimulated membrane recruitment of a PH-domain-containing protein

    S Matsuoka, M Iijima, TM Watanabe, H Kuwayama, T Yanagida, PN Devreotes, M Ueda

    JOURNAL OF CELL SCIENCE Vol. 119 No. 6 p. 1071-1079 2006/03 Research paper (scientific journal)

  49. Tumor suppressor PTEN acts through dynamic interaction with the plasma membrane

    F Vazquez, S Matsuoka, WR Sellers, T Yanagida, M Ueda, PN Devreotes

    PNAS Vol. 103 No. 10 p. 3633-3638 2006/03 Research paper (scientific journal)

  50. Total internal reflection fluorescence microscopy in single molecule nanobioscience

    T Wazawa, M Ueda

    MICROSCOPY TECHNIQUES Vol. 95 p. 77-106 2005 Research paper (scientific journal)

  51. Single-molecule analysis of chemotactic signaling in Dictyostelium cells

    M Ueda, Y Sako, T Tanaka, P Devreotes, T Yanagida

    SCIENCE Vol. 294 No. 5543 p. 864-867 2001/10 Research paper (scientific journal)

  52. Unusual centrosome cycle in Dictyostelium: Correlation of dynamic behavior and structural changes

    M Ueda, M Schliwa, U Euteneuer

    MOLECULAR BIOLOGY OF THE CELL Vol. 10 No. 1 p. 151-160 1999/01 Research paper (scientific journal)

  53. Centrosome positioning and directionality of cell movements

    M Ueda, R Graf, HK MacWilliams, M Schliwa, U Euteneuer

    PNAS Vol. 94 No. 18 p. 9674-9678 1997/09 Research paper (scientific journal)

  54. Site-Specific Clustering of Bioactive Signaling Molecules Predicted In Situ by Space and Time Coherent Mapping for Imaging Mass Spectrometry.

    Jun Aoki, Masako Isokawa, Masahiro Ueda

    Journal of the American Society for Mass Spectrometry Vol. 36 No. 1 p. 72-84 2025/01/01 Research paper (scientific journal)

  55. RasGEFX triggers spontaneous Ras excitation with RasGEFB/M/U for random cell migration

    Koji Iwamoto, Satomi Matsuoka, Masahiro Ueda

    2023/08/14 Research paper (scientific journal)

    Publisher: Cold Spring Harbor Laboratory
  56. The specific core fucose-binding lectin Pholiota squarrosa lectin (PhoSL) inhibits hepatitis B virus infection in vitro.

    Tsunenori Ouchida, Haruka Maeda, Yuka Akamatsu, Megumi Maeda, Shinji Takamatsu, Jumpei Kondo, Ryo Misaki, Yoshihiro Kamada, Masahiro Ueda, Keiji Ueda, Eiji Miyoshi

    Scientific reports Vol. 13 No. 1 p. 6175-6175 2023/04/15 Research paper (scientific journal)

  57. A dynamic partitioning mechanism polarizes membrane protein distribution.

    Tatsat Banerjee, Satomi Matsuoka, Debojyoti Biswas, Yuchuan Miao, Dhiman Sankar Pal, Yoichiro Kamimura, Masahiro Ueda, Peter N Devreotes, Pablo A Iglesias

    bioRxiv : the preprint server for biology 2023/01/03 Research paper (scientific journal)

  58. Calcium responses to external mechanical stimuli in the multicellular stage of Dictyostelium discoideum.

    Hidenori Hashimura, Yusuke V Morimoto, Yusei Hirayama, Masahiro Ueda

    Scientific reports Vol. 12 No. 1 p. 12428-12428 2022/07/20 Research paper (scientific journal)

  59. SRC kinase activator CDCP1 promotes hepatocyte growth factor-induced cell migration/invasion of a subset of breast cancer cells.

    Naoyuki Kawase, Atsuya Sugihara, Kentaro Kajiwara, Michio Hiroshima, Kanako Akamatsu, Shigeyuki Nada, Kunio Matsumoto, Masahiro Ueda, Masato Okada

    The Journal of biological chemistry Vol. 298 No. 3 p. 101630-101630 2022/01/24 Research paper (scientific journal)

  60. Comparative Analysis of Single-Molecule Dynamics of TRPV1 and TRPV4 Channels in Living Cells.

    Yutaro Kuwashima, Masataka Yanagawa, Mitsuhiro Abe, Michio Hiroshima, Masahiro Ueda, Makoto Arita, Yasushi Sako

    International journal of molecular sciences Vol. 22 No. 16 2021/08/06 Research paper (scientific journal)

  61. GPCR Signaling Regulation in Dictyostelium Chemotaxis.

    Yoichiro Kamimura, Masahiro Ueda

    Methods in molecular biology (Clifton, N.J.) Vol. 2274 p. 317-336 2021 Research paper (scientific journal)

  62. Intracellular ATP levels influence cell fates in Dictyostelium discoideum differentiation.

    Haruka Hiraoka, Tadashi Nakano, Satoshi Kuwana, Masashi Fukuzawa, Yasuhiro Hirano, Masahiro Ueda, Tokuko Haraguchi, Yasushi Hiraoka

    Genes to cells : devoted to molecular & cellular mechanisms Vol. 25 No. 5 p. 312-326 2020/05 Research paper (scientific journal)

  63. Talin B regulates collective cell migration via PI3K signaling in Dictyostelium discoideum mounds.

    Shin-Ichi Yamazaki, Hidenori Hashimura, Yusuke V Morimoto, Yukihiro Miyanaga, Satomi Matsuoka, Yoichiro Kamimura, Masahiro Ueda

    Biochemical and biophysical research communications Vol. 525 No. 2 p. 372-377 2020/04/30 Research paper (scientific journal)

  64. Large-scale single-molecule imaging aided by artificial intelligence.

    Michio Hiroshima, Masato Yasui, Masahiro Ueda

    Microscopy (Oxford, England) Vol. 69 No. 2 p. 69-78 2020/04/08 Research paper (scientific journal)

  65. A study of wound repair in Dictyostelium cells by using novel laserporation

    Pervin, M.S, Itoh, G, Talukder, M.S, Fujimoto, K, Morimoto, Y.V, Tanaka, M, Ueda, M, Yumura, S

    Scientific Report 2018/05 Research paper (scientific journal)

  66. Intracellular Protein-Labeling Probes for Multicolor Single-Molecule Imaging of Immune Receptor-Adaptor Molecular Dynamics

    Ryota Sato, Jun Kozuka, Masahiro Ueda, Reiko Mishima, Yutaro Kumagai, Akimasa Yoshimura, Masafumi Minoshima, Shin Mizukami, Kazuya Kikuchi

    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY Vol. 139 No. 48 p. 17397-17404 2017/12 Research paper (scientific journal)

  67. Multi-state transition kinetics of intracellular signaling molecules by single-molecule imaging analysis

    Satomi Matsuoka, Yukihiro Miyanaga, Masahiro Ueda

    Methods in Molecular Biology Vol. 1407 p. 361-379 2016 Part of collection (book)

    Publisher: Humana Press Inc.
  68. A Computational Framework for Bioimaging Simulation

    Masaki Watabe, Satya N. V. Arjunan, Seiya Fukushima, Kazunari Iwamoto, Jun Kozuka, Satomi Matsuoka, Yuki Shindo, Masahiro Ueda, Koichi Takahashi

    PLOS ONE Vol. 10 No. 7 2015/07 Research paper (scientific journal)

  69. A RabGAP regulates life-cycle duration via trimeric G-protein cascades in Dictyostelium discoideum

    Hidekazu Kuwayama, Yukihiro Miyanaga, Hideko Urushihara, Masahiro Ueda

    PLoS ONE Vol. 8 No. 12 2013/12/11 Research paper (scientific journal)

  70. Dynamin contributes to cytokinesis by stabilizing actin filaments in the contractile ring

    A. Y. K. Md Masud Rana, Masatsune Tsujioka, Shinya Miyagishima, Masahiro Ueda, Shigehiko Yumura

    GENES TO CELLS Vol. 18 No. 8 p. 621-635 2013/08 Research paper (scientific journal)

  71. 生命動態におけるバイオイメージング

    上田昌宏

    2013/01 Research paper (other academic)

  72. 走化性情報処理システムの多階層イメージング解析

    上田昌宏

    2012/12 Research paper (other academic)

  73. Video-Rate Confocal Microscopy for Single-Molecule Imaging in Live Cells and Superresolution Fluorescence Imaging

    Jinwoo Lee, Yukihiro Miyanaga, Masahiro Ueda, Sungchul Hohng

    BIOPHYSICAL JOURNAL Vol. 103 No. 8 p. 1691-1697 2012/10 Research paper (scientific journal)

  74. Single-molecule imaging of stochastic signaling events in living cells.

    Matsuoka S, Miyanaga Y, Yanagida T, Ueda M

    Cold Spring Harbor protocols Vol. 2012 No. 3 p. 267-278 2012/03

  75. Preparation of chemotactically competent Dictyostelium cells.

    Matsuoka S, Miyanaga Y, Yanagida T, Ueda M

    Cold Spring Harbor protocols Vol. 2012 No. 3 p. 344-345 2012/03

  76. Preparation of an imaging chamber for visualizing single molecules in living Dictyostelium cells.

    Matsuoka S, Miyanaga Y, Yanagida T, Ueda M

    Cold Spring Harbor protocols Vol. 2012 No. 3 p. 346-348 2012/03

  77. Visualizing single molecules in living Dictyostelium cells using total internal reflection fluorescent microscopy (TIRFM).

    Matsuoka S, Miyanaga Y, Yanagida T, Ueda M

    Cold Spring Harbor protocols Vol. 2012 No. 3 p. 349-351 2012/03

  78. Single-molecule kinetic analysis of stochastic signal transduction mediated by G-protein coupled chemoattractant receptors

    Yukihiro Miyanaga, Masahiro Ueda

    Cell Signaling Reactions: Single-Molecular Kinetic Analysis p. 33-57 2011 Part of collection (book)

    Publisher: Springer Netherlands
  79. Cell signaling reactions: Single-molecular kinetic analysis

    Yasushi Sako, Masahiro Ueda

    Cell Signaling Reactions: Single-Molecular Kinetic Analysis p. 1-330 2011

    Publisher: Springer Netherlands
  80. Single-molecule imaging analysis of stochastic signal transduction in chemotactic response.

    Miyanaga Y, Ueda M

    Protein, nucleic acid and enzyme Vol. 54 No. 15 p. 1928-1936 2009/12

    Publisher:
  81. [Single-molecule imaging analysis of stochastic signal transduction in chemotactic response].

    Miyanaga Y, Ueda M

    Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme Vol. 54 No. 15 p. 1928-1936 2009/12

    Publisher:
  82. Single-molecule imaging techniques to visualize chemotactic signaling events on the membrane of living Dictyostelium cells.

    Miyanaga Y, Matsuoka S, Ueda M

    Methods in molecular biology (Clifton, N.J.) Vol. 571 p. 417-435 2009

  83. Biologically-inspired stochastic vector matching for noise-robust information processing

    Michihito Ueda, Masahiro Ueda, Hiroaki Takagi, Masayuki J. Sato, Toshio Yanagida, Ichiro Yamashita, Kentaro Setsune

    PHYSICA A-STATISTICAL MECHANICS AND ITS APPLICATIONS Vol. 387 No. 16-17 p. 4475-4481 2008/07 Research paper (scientific journal)

  84. DNA oligonucleotide-assisted genetic manipulation increases transformation and homologous recombination efficiencies: Evidence from gene targeting of Dictyostelium discoideum

    Hidekazu Kuwayama, Toshio Yanagida, Masahiro Ueda

    JOURNAL OF BIOTECHNOLOGY Vol. 133 No. 4 p. 418-423 2008/02 Research paper (scientific journal)

  85. 細胞内シグナル伝達反応の1分子イメージング解析

    宮永之寛, 上田昌宏

    2007/04

  86. 2P236 Directional reversal of electrotactic movements in cyclic GMP metabolic mutants(39. Cell motility,Poster Session,Abstract,Meeting Program of EABS & BSJ 2006)

    Sato, Masayuki J, Kuwayama, Hidekazu, Takagi, Hiroaki, Yanagida, Toshio, Ueda, Masahiro

    Biophysics Vol. 46 No. 2 2006/10 Research paper (scientific journal)

    Publisher: The Biophysical Society of Japan
  87. [Stochastic fluctuations in cellular signal transduction systems].

    Shibata T, Ueda M

    Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme Vol. 50 No. 15 p. 1940-1947 2005/12

  88. Single-molecule analysis of chemotactic signaling mediated by camp receptor on living cells

    Masahiro Ueda, Yukihiro Miyanaga, Toshio Yanagida

    G Protein-Coupled Receptors: Structure, Function, and Ligand Screening p. 197-218 2005/01/01 Part of collection (book)

    Publisher: CRC Press
  89. Fluctuations and cellular responses in chemotactic signaling system

    Ueda M.

    Seibutsu Butsuri Vol. 43 2003

    Publisher: The Biophysical Society of Japan General Incorporated Association
  90. Comparative structural, molecular, and functional aspects of the Dictyostelium discoideum centrosome

    R Graf, N Brusis, C Daunderer, U Euteneuer, A Hestermann, M Schliwa, M Ueda

    CENTROSOME IN CELL REPLICATION AND EARLY DEVELOPMENT Vol. 49 p. 161-185 2000 Research paper (scientific journal)

  91. Microtubule-dependent migration of the cell nucleus toward a future leading edge in amoebae of Physarum polycephalum

    M Ueda, T Kuroiwa, S Matsunaga, S Ogihara

    PROTOPLASMA Vol. 211 No. 3-4 p. 172-182 2000 Research paper (scientific journal)

  92. Single-Molecule Imaging of Signaling Molecules in Living Cells

    Yasushi Sako, Kayo Hibino, Takayuki Miyauchi, Yoshikazu Miyamoto, Masahiro Ueda, Toshio Yanagida

    Single Molecules Vol. 1 No. 2 p. 159-163 2000 Research paper (scientific journal)

    Publisher: Wiley-VCH Verlag
  93. Unusual centrosome cycle in Dictyostelium: Correlation of dynamic behavior and structural changes

    M Ueda, M Schliwa, U Euteneuer

    MOLECULAR BIOLOGY OF THE CELL Vol. 10 No. 1 p. 151-160 1999/01 Research paper (scientific journal)

  94. Centrosomes, microtubules and cell migration

    M Schliwa, U Euteneuer, R Graf, M Ueda

    CELL BEHAVIOUR: CONTROL AND MECHANISM OF MOTILITY Vol. 65 p. 223-231 1999 Research paper (scientific journal)

  95. Isolation of nucleation-competent centrosomes from Dictyostelium discoideum

    R Graf, U Euteneuer, M Ueda, M Schliwa

    EUROPEAN JOURNAL OF CELL BIOLOGY Vol. 76 No. 3 p. 167-175 1998/07 Research paper (scientific journal)

  96. MICROTUBULES ARE REQUIRED IN AMEBA CHEMOTAXIS FOR PREFERENTIAL STABILIZATION OF APPROPRIATE PSEUDOPODS

    M UEDA, S OGIHARA

    JOURNAL OF CELL SCIENCE Vol. 107 No. 8 p. 2071-2079 1994/08 Research paper (scientific journal)

  97. INTERACTION OF THE LOW-MOLECULAR-MASS, GUANINE-NUCLEOTIDE-BINDING PROTEIN WITH THE ACTIN-BINDING PROTEIN AND ITS MODULATION BY THE CAMP-DEPENDENT PROTEIN-KINASE IN BOVINE PLATELETS

    M UEDA, C OHO, H TAKISAWA, S OGIHARA

    EUROPEAN JOURNAL OF BIOCHEMISTRY Vol. 203 No. 3 p. 347-352 1992/02 Research paper (scientific journal)

  98. REPRESSION OF SEROTONIN SECRETION BY AN ENDOGENOUS CA-2+-ACTIVATED PROTEASE IN ELECTROPERMEABILIZED BOVINE PLATELETS

    T MORIMOTO, C OHO, M UEDA, S OGIHARA, H TAKISAWA

    JOURNAL OF BIOCHEMISTRY Vol. 108 No. 2 p. 311-320 1990/08 Research paper (scientific journal)

  99. Repression of serotonin secretion by an endogenous Ca2(+)-activated protease in electropermeabilized bovine platelets

    Morimoto T, Oho C, Ueda M, Ogihara S, Takisawa H

    J Biochem Vol. 108 No. 2 p. 311-320 1990 Research paper (scientific journal)

Misc. 71

  1. Full Automation of Single-molecule Imaging and Application to Large-scale Analysis

    廣島通夫, 上田昌宏

    生産と技術 Vol. 75 No. 2 2023

  2. 自動1分子イメージング法の開発と創薬基盤技術への展開

    上田昌宏

    日本解剖学会総会・全国学術集会抄録集(CD-ROM) Vol. 128th 2023

  3. Self-organization of polarity for cell migration mediated by an excitable system

    松岡里実, 松岡里実, 上田昌宏, 上田昌宏

    日本分子生物学会年会プログラム・要旨集(Web) Vol. 46th 2023

  4. GPCR signaling for eukaryotic chemotaxis

    上田昌宏, 上村陽一郎

    Bio Clinica Vol. 37 No. 11 2022

  5. Mechanism of mechanosensing in multicellular bodies of Dctyostelium discoideum

    森本雄祐, 橋村秀典, 平山悠成, 上田昌宏

    日本生体エネルギー研究会討論会講演要旨集 Vol. 46th 2020

  6. 三量体G蛋白質シャトリング制御

    上村陽一郎, 上田昌宏

    医学のあゆみ Vol. 272 No. 7 2020

  7. 細胞性粘菌のcAMPシグナルリレーを調節する膜電位変化

    森本雄祐, 森本雄祐, 上田昌宏, 上田昌宏

    日本分子生物学会年会プログラム・要旨集(Web) Vol. 42nd 2019

  8. Elucidation of mechanosensing system in the multicellular body of Dctyostelium discoideum

    平山悠成, 橋村秀典, 上田昌宏, 森本雄祐

    日本生体エネルギー研究会討論会講演要旨集 Vol. 45th 2019

  9. 【生きてるものは全部観る!イメージングの選び方・使い方100+】(第4章)超解像顕微鏡 PALM/STORM

    廣島 通夫, 上田 昌宏

    実験医学 Vol. 36 No. 20 p. 3440-3441 2018/12

    Publisher: (株)羊土社
  10. 細胞性粘菌リソースと研究への利用

    上村陽一郎, 桑山秀一, 上田昌宏

    日本植物学会大会研究発表記録 Vol. 82nd 2018/09/01

  11. 三量体Gタンパク質可溶化因子による走化性GPCRシグナル伝達制御

    KAMIMURA Yoichiro, MIYAGAWA Takero, KOTEISHI Hiroyasu, UEDA Masahiro, UEDA Masahiro

    日本分子生物学会年会プログラム・要旨集(Web) Vol. 41st 2018

  12. PTEN-PI (4, 5)P2 positive feedback mechanism for stabilizing asymmetric PI (3, 4, 5)P3 localization in migrating cell

    YOSHIOKA Daisuke, YOSHIOKA Daisuke, KOTEISHI Hiroyasu, OKUNO Daichi, MATSUOKA Satomi, IDE Toru, UEDA Masahiro, UEDA Masahiro

    生物物理(Web) Vol. 58 No. Supplement 1-2 2018

  13. 細胞性粘菌における単細胞から多細胞へのシグナル伝達様式の変遷

    橋村秀典, 橋村秀典, 森本雄祐, 森本雄祐, 安井真人, 上田昌宏, 上田昌宏

    日本生体エネルギー研究会討論会講演要旨集 Vol. 44th 2018

  14. Dynamic Range Extension of Eukaryotic Chemotaxis through the Regulation of G Protein Localization

    宮永之寛, 上村陽一郎, 上田昌宏

    生物物理(Web) Vol. 58 No. 5 2018

  15. 三量体G蛋白質シャトリングを支えるGip1‐G γ複合体形成の構造解析

    宮川武朗, 上村陽一郎, 小手石泰康, 竹下浩平, 中川敦史, 上田昌宏, 上田昌宏

    日本蛋白質科学会年会プログラム・要旨集 Vol. 17th 2017/05/22

  16. 細胞の集団運動に関わる電気化学ポテンシャル変化の高感度イメージング

    森本雄祐, 上田昌宏, 上田昌宏

    日本物理学会講演概要集(CD-ROM) Vol. 72 No. 1 2017

  17. In vitro1分子イメージングによるPTEN-PI(4,5)P2相互作用の解析

    好岡大輔, 福島誠也, 福島誠也, 奥野大地, 松岡里実, 井出徹, 上田昌宏, 上田昌宏

    日本細胞生物学会大会(Web) Vol. 69th 2017

  18. Comprehensive alanine scanning analysis of heterotrimeric G protein interacting partner Gip1

    KOTEISHI Hiroyasu, MIYAGAWA Takero, KAMIMURA Yoichiro, MIYANAGA Yukihiro, UEDA Masahiro, UEDA Masahiro

    生物物理(Web) Vol. 57 No. Supplement 1-2 2017

  19. Gip1 sequesters heterotrimeric G proteins in the cytosol by masking their lipid-modification site with the hydrophobic cavity

    MIYAGAWA Takero, KAMIMURA Yoichiro, KOTEISHI Hiroyasu, TAKESHITA Kohei, NAKAGAWA Atsushi, UEDA Masahiro, UEDA Masahiro

    生物物理(Web) Vol. 57 No. Supplement 1-2 2017

  20. GPCRシグナル伝達系における三量体Gタンパク質シャトリングの分子機構

    KAMIMURA Yoichiro, MIYAGAWA Takero, KOTEISHI Hiroyasu, UEDA Masahiro, KAMIMURA Yoichiro, MIYAGAWA Takero, KOTEISHI Hiroyasu, UEDA Masahiro

    日本生化学会大会(Web) Vol. 90th 2017

  21. 真核生物のシグナル伝達を調節する膜電位変動

    森本雄祐, 森本雄祐, 上田昌宏, 上田昌宏

    日本生体エネルギー研究会討論会講演要旨集 Vol. 43rd 2017

  22. Gip1の構造から見えてきた三量体Gタンパク質シャトリングの分子基盤

    上村陽一郎, 宮川武朗, 小手石泰康, 上田昌宏, 上田昌宏

    GPCR研究会プログラム・抄録集 Vol. 14th 2017

  23. PTENを介したArfGTPaseによる細胞運動の制御機構

    出川拓馬, 松岡里実, 森本雄祐, 上村陽一郎, 上田昌宏, 上田昌宏

    日本細胞生物学会大会(Web) Vol. 69th 2017

  24. A mechanism of asymmetric PTEN distribution revealed by in vitro single-molecule imaging analysis

    YOSHIOKA Daisuke, FUKUSHIMA Seiya, FUKUSHIMA Seiya, KOTEISHI Hiroyasu, OKUNO Daichi, MATSUOKA Satomi, IDE Toru, UEDA Masahiro, UEDA Masahiro

    日本細胞生物学会大会(Web) Vol. 68th 2016

  25. Phosphatidylinositol lipid PI(4,5)P2 enhances membrane binding of PTEN revealed by single-molecule imaging on artificial lipid bilayers

    YOSHIOKA Daisuke, FUKUSHIMA Seiya, FUKUSHIMA Seiya, KOTEISHI Hiroyasu, OKUNO Daichi, MATSUOKA Satomi, IDE Toru, UEDA Masahiro, UEDA Masahiro

    日本蛋白質科学会年会プログラム・要旨集 Vol. 16th 2016

  26. Small Cell Aggregation Method Which Enables us to Observe All Cell's Behavior Individually

    Haruka Hiraoka, Masahiro Ueda

    BIOPHYSICAL JOURNAL Vol. 108 No. 2 p. 150A-150A 2015/01 Research paper, summary (international conference)

  27. Nucleocytoplasmic Shuttling of a Gata-Family Transcription Factor Functions as a Development Timer

    Huaqing Cai, Mariko Katoh-Kurasawa, Tetsuya Muramoto, Balaji Santhanam, Yu Long, Lei Li, Masahiro Ueda, Pablo A. Iglesias, Gad Shaulsky, Peter N. Devreotes

    BIOPHYSICAL JOURNAL Vol. 108 No. 2 p. 463A-463A 2015/01 Research paper, summary (international conference)

  28. 三量体Gタンパク質シャトリングの制御機構と走化性における役割

    上村陽一郎, 宮永之寛, 上田昌宏, 上村陽一郎, 宮永之寛, 上田昌宏

    日本生化学会大会(Web) Vol. 88th 2015

  29. Robust Gradient Sensing in a Fluctuating Signaling System for Eukaryotic Chemotaxis

    Vol. 33 No. 6 p. 592-597 2014

    Publisher: 学研メディカル秀潤社 ; 1982-
  30. Robust Cellular Information Processing Based on Fluctuations in Cell Motility

    Vol. 33 No. 1 p. 48-54 2014

    Publisher: 学研メディカル秀潤社 ; 1982-
  31. Excitability of Guanylate Cyclase Signaling Pathway Mediating Chemotaxis

    Yuki Tanabe, Masahiro Ueda

    BIOPHYSICAL JOURNAL Vol. 106 No. 2 p. 522A-522A 2014/01 Research paper, summary (international conference)

  32. Control of Cell Excitability through Microtubule Network

    Takuma Degawa, Satomi Matsuoka, Masahiro Ueda

    BIOPHYSICAL JOURNAL Vol. 106 No. 2 p. 595A-595A 2014/01 Research paper, summary (international conference)

  33. Simultaneous Imaging of Single-Molecule and Bulk Localization of Pten

    Seiya Fukushima, Satomi Matsuoka, Masahiro Ueda

    BIOPHYSICAL JOURNAL Vol. 106 No. 2 p. 518A-518A 2014/01 Research paper, summary (international conference)

  34. Regulation for Phosphatidylinositol Lipids Signaling System by Talin

    Shinichi Yamazaki, Satomi Matsuoka, Masatsune Tsujioka, Masahiro Ueda

    BIOPHYSICAL JOURNAL Vol. 106 No. 2 p. 785A-785A 2014/01 Research paper, summary (international conference)

  35. 走化性における濃度勾配認識に関与する新規三量体Gタンパク質結合因子Gip1の解析

    上村陽一郎, 宮永之寛, 上田昌宏

    日本分子生物学会年会プログラム・要旨集(Web) Vol. 37th 2014

  36. G Protein Coupled Chemoattractant Receptor Modulates the Diffusion and Membrane Binding of Activated G alpha via their Association

    Yukihiro Miyanaga, Masahiro Ueda

    BIOPHYSICAL JOURNAL Vol. 104 No. 2 p. 116A-117A 2013/01 Research paper, summary (international conference)

  37. 新規三量体Gタンパク質結合因子の走化性における役割

    上村陽一郎, 宮永之寛, 上田昌宏

    日本分子生物学会年会プログラム・要旨集(Web) Vol. 36th 2013

  38. pH感受性蛍光タンパク質を用いた細胞性粘菌の細胞内pH測定

    森本雄祐, 西原絵里, 上田昌宏, 上田昌宏

    日本分子生物学会年会プログラム・要旨集(Web) Vol. 35th 2012

  39. Regulation of Self-Organization in Chemotactic Signaling System by an Adhesion-Related Molecule, Talin

    Shinichi Yamazaki, Satomi Matsuoka, Masatsune Tsujioka, Masahiro Ueda

    BIOPHYSICAL JOURNAL Vol. 102 No. 3 p. 160A-160A 2012/01 Research paper, summary (international conference)

  40. 走化性を制御するシグナル伝達経路のネットワーク構成

    上村陽一郎, 田口静香, 田邊香, 上田昌宏

    日本分子生物学会年会プログラム・要旨集(Web) Vol. 35th 2012

  41. Stochastic signaling in living cells revealed by single-molecule imaging

    Vol. 66 No. 10 p. 2384-2390 2011/10

    Publisher: 最新医学社
  42. 24aPS-33 Dynamics of spontaneous cell migration and its relevance to electrotaxis in Dictyostelium cells

    Takagi Hiroaki, Sato Masayuki J., Ueda Masahiro

    Meeting abstracts of the Physical Society of Japan Vol. 66 No. 2 p. 346-346 2011/08/24

    Publisher: The Physical Society of Japan (JPS)
  43. Self-Organization of the Phosphatidylinositol Lipids Signaling System for Random Cell Migration

    Tatsuo Shibata, Arai Yoshiyuki, Matsuoka Satomi, Sato J. Masayuki, Ueda Masahiro

    BIOPHYSICAL JOURNAL Vol. 100 No. 3 p. 33-33 2011/02 Research paper, summary (international conference)

  44. Statistical Analysis of Lateral Diffusion and Kinetics of State Transition and Membrane Dissociation in Single Molecule Imaging

    Satomi Matsuoka, Tatsuo Shibata, Masahiro Ueda

    BIOPHYSICAL JOURNAL Vol. 100 No. 3 p. 252-252 2011/02 Research paper, summary (international conference)

  45. Preface

    Yasushi Sako, Masahiro Ueda

    Cell Signaling Reactions: Single-Molecular Kinetic Analysis p. v-vi 2011 Other

    Publisher: Springer Netherlands
  46. 26pPSA-46 Functional significance of spontaneous cell migration for electortaxis in Dictyostelium cells

    Takagi Hiroaki, Sato Masayuki J., Ueda Masahiro

    Meeting abstracts of the Physical Society of Japan Vol. 64 No. 2 p. 280-280 2009/08/18

    Publisher: The Physical Society of Japan (JPS)
  47. D-7-2 Application of stochastic vector matching to the model of galvanotactic migration of cells

    Ueda Michihito, Sato Masayuki J., Ueda Masahiro

    Proceedings of the IEICE General Conference Vol. 2009 No. 1 p. 79-79 2009/03/04

    Publisher: The Institute of Electronics, Information and Communication Engineers
  48. 745 Dynamical Features of Bio-molecular Machines : A Comparative Study Using Coarse-Grained Molecular Dynamics Simulations

    TOGASHI Yuichi, UEDA Masahiro, MIKHAILOV Alexander S., YANAGIDA Toshio

    The Computational Mechanics Conference Vol. 2008 No. 21 p. 856-857 2008/11/01

    Publisher: The Japan Society of Mechanical Engineers
  49. 21aWE-2 Functional relationship between spontaneous cell movement and electrotaxis in Dictyostelium discoideum

    Takagi Hiroaki

    Meeting abstracts of the Physical Society of Japan Vol. 63 No. 2 p. 311-311 2008/08/25

    Publisher: The Physical Society of Japan (JPS)
  50. 20aPS-99 Nonlinear Relaxation Dynamics in Elastic Networks : A Comparative Study on Motion of Molecular Motors

    Togashi Yuichi, Ueda Masahiro, Mikhailov Alexander S., Yanagida Toshio

    Meeting abstracts of the Physical Society of Japan Vol. 63 No. 2 p. 287-287 2008/08/25

    Publisher: The Physical Society of Japan (JPS)
  51. A-2-1 Noise-robust Information Processing by Stochastic Signal Conversion.

    Ueda Michihito, Ueda Masahiro, Takagi Hiroaki, Yamashita Ichiro

    Proceedings of the IEICE General Conference Vol. 2008 p. 40-40 2008/03/05

    Publisher: The Institute of Electronics, Information and Communication Engineers
  52. 21pRK-6 Nonlinear Relaxation Dynamics in Elastic Networks and Dynamical Properties of Biological Molecular Machines

    Togashi Yuichi, Ueda Masahiro, Mikhailov Alexander S., Yanagida Toshio

    Meeting abstracts of the Physical Society of Japan Vol. 62 No. 2 p. 356-356 2007/08/21

    Publisher: The Physical Society of Japan (JPS)
  53. 18pTC-5 Analysis of spontaneous cell movement in the developmental process of Dictyostelium cells

    Takagi Hiroaki, Sato Masayuki J., Yanagida Toshio, Ueda Masahiro

    Meeting abstracts of the Physical Society of Japan Vol. 62 No. 1 p. 330-330 2007/02/28

    Publisher: The Physical Society of Japan (JPS)
  54. 細胞に学ぶ確率的分子情報処理(SessionII : 運動,動的システムの情報論5-微小生物の生態と運動-)

    上田 昌宏, 柴田 達夫

    物性研究 Vol. 87 No. 6 p. 898-906 2007

    Publisher: 物性研究刊行会
  55. 細胞の反応ゆらぎとシグナル伝達 (特集 数理生物学)

    柴田 達夫, 上田 昌宏

    蛋白質核酸酵素 Vol. 50 No. 15 p. 1940-1947 2005/12

    Publisher: 共立出版
  56. Single-molecule imaging of chemotactic signaling in living cells

    M Ueda, T Yanagida

    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY Vol. 230 p. U305-U306 2005/08 Research paper, summary (international conference)

  57. Single molecular detection of G gamma on plasma membrane during Diclyostelium chemotactic migration

    Masahiro Takahashi, Hidekazu Kuwayama, Masahiro Ueda, Toshio Yanagida

    CELL STRUCTURE AND FUNCTION Vol. 30 p. 55-55 2005/06 Research paper, summary (international conference)

  58. 【シグナル伝達研究2005-'06 生命現象や疾患を支配する分子メカニズムと新しい研究法 現在と未来】 シグナル伝達研究における新たなアプローチ 情報伝達分子の生細胞イメージング

    岩根敦子, 上田昌宏, 日比野佳代, 佐甲靖志, 柳田敏雄

    実験医学 Vol. 23 No. 11 p. 1796-1802 2005/06

    Publisher: (株)羊土社
  59. Aberrant regulation of PI(3,4,5)P-3-dependent pathway in a lipid metabolism mutant during normal chemotaxis

    S Matsuoka, M Ueda, H Kuwayama, T Yanagida

    BIOPHYSICAL JOURNAL Vol. 88 No. 1 p. 432A-432A 2005/01 Research paper, summary (international conference)

  60. Aberrant regulation of PI(3,4,5)P3-dependent pathway in a lipid metabolism mutant during normal chemotaxis

    S Matsuoka, M Ueda, H Kuwayama, T Yanagida

    BIOPHYSICAL JOURNAL Vol. 88 No. 1 p. 595A-595A 2005/01 Research paper, summary (international conference)

  61. Phosphatase activity of PTEN enhanced by PI(4,5)P-2-binding

    Satomi Matsuoka, Masahiro Ueda, Hidekazu Kuwayama, Peter Devreotes, Toshio Yanagida

    CELL STRUCTURE AND FUNCTION Vol. 29 p. 60-60 2004/05 Research paper, summary (international conference)

  62. Single molecule analysis of g-protein-coupled receptors in living dietyostelium cells

    Y Miyanaga, M Ueda, H Kuwayama, P Devreotes, T Yanagida

    BIOPHYSICAL JOURNAL Vol. 86 No. 1 p. 445A-445A 2004/01 Research paper, summary (international conference)

  63. Molecular mechanism of nano-biomachines

    UEDA Masahiro, ISHII Yoshiharu, YANAGIDA Toshio

    Vol. 71 No. 12 p. 1457-1466 2002/12/10

    Publisher: 応用物理学会
  64. Single-molecule analysis of chemotactic signaling in Dictyostelium cells

    M Ueda, Y Sako, T Tanaka, PN Devreotes, T Yanagida

    BIOPHYSICAL JOURNAL Vol. 82 No. 1 p. 222A-222A 2002/01 Research paper, summary (international conference)

  65. Single-molecule imaging of intracellular signaling.

    Sako Y, Ueda M, Ichinose J, Miyauchi T, Uyemura T, Hibino K, Ohta K, Yanagida T

    Seibutsu Butsuri Vol. 40 No. 0 2000

    Publisher: 一般社団法人 日本生物物理学会
  66. Single molecule analysis of chemotaxis in Dictyostelium

    Ueda M, Tanaka T, Sako Y, Yanagida T

    Seibutsu Butsuri Vol. 40 No. 0 2000

    Publisher: 一般社団法人 日本生物物理学会
  67. Synthesis of fluorescent analogs of cyclic AMP which serves as a chemoattractant in Dictyostelium

    Ueda M, Tanaka T, Sako Y, Yanagida T

    Seibutsu Butsuri Vol. 39 No. 0 1999

    Publisher: 一般社団法人 日本生物物理学会
  68. Presence of force in amoebae of Physarum polycephalum which pulls the centrosome toward the pseudopod at the leading edge during locomotion.

    M Ueda, T Kuroiwa, S Matsunaga, S Ogihara

    MOLECULAR BIOLOGY OF THE CELL Vol. 8 p. 2245-2245 1997/11 Research paper, summary (international conference)

  69. Microtubule-dependent migration of the cell nucleus toward a future leading edge in amoebae of Physarum polycephalum during chemotaxis.

    M Ueda, S Ogihara

    MOLECULAR BIOLOGY OF THE CELL Vol. 7 p. 3266-3266 1996/12 Research paper, summary (international conference)

  70. A new hypothesis for amoeba chemotaxis: integration of chemoattractant information by force exerted on the centrosome

    OGIHARA Satoshi, UEDA Masahiro

    Seibutsu Butsuri Vol. 36 No. 2 p. 95-100 1996

    Publisher: The Biophysical Society of Japan General Incorporated Association
  71. Comparison of protein tyrosine phosphorylation and morphological changes induced by IL-2 and IL-3.

    H Sabe, J Kuno, A Koromilas, Y Saito, T Kinashi, M Ueda, T Takamatsu, M Hamaguchi, T Kawakami, T Honjo

    International immunology Vol. 3 No. 11 p. 1137-1148 1991

Publications 15

  1. 1分子自動イメージング法の開発と細胞への適用 ― 細胞内1分子スクリーニングの実現へ向けて

    上田昌宏

    日本の科学者 2019/05 Scholarly book

  2. 三量体Gタンパク質の局在制御を介した走化性レンジの拡張機構

    宮永之寛, 上村陽一郎, 上田昌宏

    生物物理 2018/09 Scholarly book

  3. イノシトールリン脂質シグナル

    松岡里実, 上田昌宏

    生体の科学, 増大特集 『細胞シグナル操作法』 2015/09 Scholarly book

  4. 『1分子生物学』, 11章 細胞膜内での運動,11-3 細胞表面における情報処理

    松岡里実, 上田昌宏

    DOJIN BIOSCIENCE SERIES, (化学同人) 2014/12 Scholarly book

  5. 1分子イメージングによる走化性情報伝達系の動態解析

    松岡里実, 上田昌宏

    生体の科学 『生命動態システム科学』 2014/12 Scholarly book

  6. ゆらぎの伴うシグナル伝達系による走化性細胞のロバストな勾配センシング

    柴田達夫, 西川正俊, 上田昌宏

    細胞工学(学研メディカル秀潤社) 2014/06 Scholarly book

  7. 2013年:「生命動態のシステム科学」零年

    上田昌宏

    パリティー(丸善) 2014/01 Scholarly book

  8. 細胞運動のゆらぎから探るロバストな細胞情報処理機構

    高木拓明, 佐藤雅之, 上田昌宏

    細胞工学 (学研メディカル秀潤社) 2014/01 Scholarly book

  9. Physics of eukaryotic chemotaxis

    Masahiro Ueda

    2013/12 Other

  10. 蛋白質蛍光1分子解析

    小森智貴, 宮永之寛, 上田昌宏

    丸善出版 2012/11 Scholarly book

    ISBN: 9784621086155

  11. 試料分析講座 タンパク質分析

    小森智貴, 宮永之寛, 上田昌宏

    丸善出版株式会社 2012/11 Scholarly book

    ISBN: 4621086154

  12. 生命科学の新しい潮流 理論生物学

    柴田達夫, 上田昌宏

    共立出版 2011/01 Scholarly book

  13. Cell Signaling Reactions: Single-Molecule Kinetic Analysis.

    Y. Sako, M. Ueda, Editors

    Springer-Verlag. 2011/01 Scholarly book

    ISBN: 9789048198634

  14. Single molecule imaging of stochastic signaling events in living cells.

    Matsuoka, S, Miyanaga, Y, Yanagida, T, Ueda, M

    Cold Spring Harbor Laboratory Press 2007/12 Scholarly book

    ISBN: 9780879697754

  15. Single-molecule analysis of chemotactic signaling mediated by cAMP receptor on living cells. In Methods in signal transduction series: G protein-coupled receptors: Structure, Function and Ligand Screening.

    Ueda, M, Miyanaga, Y, Yanagida, T

    Taylor & Francis 2005/08 Scholarly book

    ISBN: 9780849327711

Industrial Property Rights 6

  1. 光学顕微鏡システムおよびスクリーニング装置

    柳田 敏雄, 上田 昌宏, 佐甲 靖志, 廣島 通夫, 小塚 淳

    出願日:2014/05/30

  2. 多重蛍光画像の画像解析のための装置、システム、方法、およびプログラム

    尾崎 裕一, 上田 昌宏

    特許第5870821号

    出願日:2012/04/03

  3. 多重蛍光画像の画像解析のための装置、システム、方法、およびプログラム

    尾崎 裕一, 上田 昌宏

    出願日:2012/04/03

  4. 受容体型チロシンキナーゼの活性評価方法

    上田昌宏, 廣島通夫, 渡邉 大介

    出願日:2023/03/01

  5. オートフォーカス装置ならびにそれを備える光学装置および顕微鏡

    安井真人, 廣島通夫, 上田昌宏

    出願日:2018/02/14

  6. 1分子動態を指標としたGPCRの活性推定手法

    柳川正隆, 佐甲靖志, 廣島通夫, 安井真人, 上田昌宏, 冨樫祐一

    出願日:2017/04/21

Institutional Repository 3

Content Published in the University of Osaka Institutional Repository (OUKA)
  1. Excitable Ras dynamics-based screens reveal RasGEFX is required for macropinocytosis and random cell migration

    Iwamoto Koji, Matsuoka Satomi, Ueda Masahiro

    Nature Communications Vol. 16 2025/01/02

  2. Single molecule tracking based drug screening

    Watanabe Daisuke, Hiroshima Michio, Yasui Masato, Ueda Masahiro

    Nature Communications Vol. 15 2024/10/17

  3. Mechanism of sensing chemical gradients in Physarum Polycephalum amoebae

    上田 昌宏