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Yagi Takeshi

八木　健

Graduate School of Frontier Biosciences　Department of Frontier Biosciences, Professor

keyword clustered protocadherin

Education

  • - 1991/03, The University of Tokyo, Graduate School, Division of Natural Science
  • - 1988/03, Chiba University, Graduate School, Division of Natural Science
  • - 1984/03, Tokyo Metropolitan University, Faculty of Science

Research History

  • 2018/04 - Present, 大阪大学, 基礎工学部, 教授
  • 2002/04 - Present, 大阪大学大学院 生命機能研究科 教授
  • 2002/04/01 - Present, Osaka University Graduate School of Frontier Biosciences Department of Frontier Biosciences, Professor
  • 2000/11 - Present, 岡崎国立共同研究機構 生理学研究所 客員教授
  • 2007 - 2009, 大阪大学 生命機能研究科, 教授
  • 2002 - 2007, 大阪大学 大学院・生命機能研究科, 教授
  • 2005 - 2006, Osaka University, Graduate School of Frontier Biosciences
  • 2001 - 2006, Osaka University
  • 2002 - 2003, 大阪大学 生命機能研究科, 教授
  • 2000/06/01 - 2002/03/31, Osaka University Institute for Molecular and Cellular Biology, Professor
  • 2000/06 - 2002/03, 大阪大学 細胞生体工学センター 教授
  • 1997/04 - 2000/05, 岡崎国立共同研究機構 生理学研究所 助教授
  • 1997 - 2000, 岡崎国立共同研究機構, 助教授
  • 1997 - 2000, 岡崎国立共同研究機構・生理学研究所, 助教授
  • 1993/09 - 1997/03, 岡崎国立共同研究機構 生理学研究所 助手
  • 1995 - 1997, 岡崎国立共同研究機構, 助手
  • 1994 - 1997, 岡崎国立共同研究機構・生理学研究所, 助手
  • 1991/04 - 1993/08, 理化学研究所 基礎特別研究員
  • 1984/04 - 1986/03, 日本赤十字社中央血液センター 研究員
  • 2005 - , 大阪大学 大学院・生命科学研究科, 教授
  • 2002 - , 大阪大学 細胞生体工学センター・遺伝情報システム研究部門, 教授
  • 2001 - , 大阪大学細胞生体工学センター 遺伝情報システム研究部門, 教授
  • 1999 - , 岡崎国立共同研究機構, 教授
  • 1999 - , 国立岡崎共同研究機構・生理学研究所, 助教授
  • 1999 - , 岡島国立共同研究機構・生理学研究所, 助教授
  • 1998 - , 岡崎国立共同研究機構 高次神経機構, 助教授
  • 1997 - , 国立生理学研究所, 助教授
  • 1997 - , 岡崎国立共同研究機構 生理学研究所研, 助教授
  • 1994 - , 岡崎国立共同研究機構 高次神経材構, 助手
  • 1994 - , 岡崎国立共同研究機構 高次神経機構, 助手
  • 1993 - , 岡崎国立共同研究機構, 助手

Research Areas

  • Life sciences, Experimental pathology
  • Life sciences, Metabolism and endocrinology
  • Life sciences, Neuroanatomy and physiology
  • Life sciences, Laboratory animal science
  • Life sciences, Neuroscience - general
  • Life sciences, Molecular biology

Professional Memberships

  • American Association for the Advancement of Science Society for Neuroscience
  • 日本発生生物学会
  • 日本神経科学会
  • 日本分子生物学会

Papers

  • Protocol to visualize trans-interaction of clustered protocadherin using cIPAD, a fluorescent indicator, in cultured human cells and mouse neurons, Takashi Kanadome,Natsumi Hoshino,Takeharu Nagai,Takeshi Yagi,Tomoki Matsuda, STAR Protocols, Elsevier BV, Vol. 5, No. 1, p. 102844-102844, 2024/03
  • Reciprocal Connections between Parvalbumin-Expressing Cells and Adjacent Pyramidal Cells Are Regulated by Clustered Protocadherin γ, Nanami Kawamura,Tomoki Osuka,Ryosuke Kaneko,Eri Kishi,Ryuon Higuchi,Yumiko Yoshimura,Takahiro Hirabayashi,Takeshi Yagi,Etsuko Tarusawa, eneuro, Society for Neuroscience, Vol. 10, No. 10, p. ENEURO.0250-23.2023, 2023/10/27
  • Visualization of <i>trans</i> homophilic interaction of clustered protocadherin in neurons, Natsumi Hoshino,Takashi Kanadome,Tomomi Takasugi,Mizuho Itoh,Ryosuke Kaneko,Yukiko U. Inoue,Takayoshi Inoue,Takahiro Hirabayashi,Masahiko Watanabe,Tomoki Matsuda,Takeharu Nagai,Etsuko Tarusawa,Takeshi Yagi, Proceedings of the National Academy of Sciences, Proceedings of the National Academy of Sciences, Vol. 120, No. 38, 2023/09/11
  • Visualization of trans-interactions of a protocadherin-α between processes originating from single neurons, Takashi Kanadome,Natsumi Hoshino,Takeharu Nagai,Takeshi Yagi,Tomoki Matsuda, iScience, Elsevier BV, Vol. 26, No. 7, p. 107238-107238, 2023/07
  • Emergence of rhythmic chunking in complex stepping of mice, Kojiro Hirokane,Toru Nakamura,Yasuo Kubota,Dan Hu,Takeshi Yagi,Ann M. Graybiel,Takashi Kitsukawa, iScience, Elsevier BV, Vol. 26, No. 5, p. 106765-106765, 2023/05
  • Microglia enable cross-modal plasticity by removing inhibitory synapses, Akari Hashimoto,Nanami Kawamura,Etsuko Tarusawa,Ikuko Takeda,Yuki Aoyama,Nobuhiko Ohno,Mio Inoue,Mai Kagamiuchi,Daisuke Kato,Mami Matsumoto,Yoshihiro Hasegawa,Junichi Nabekura,Anne Schaefer,Andrew J. Moorhouse,Takeshi Yagi,Hiroaki Wake, Cell Reports, Elsevier BV, Vol. 42, No. 5, p. 112383-112383, 2023/05
  • Imbalanced expression of clustered protocadherins in pre- and post-synaptic compartments of CA1 pyramidal cells during hippocampal development, Etsuko Tarusawa,Saki Hasegawa,Daisuke Noda,Nanami Kawamura,Yugo Fukazawa,Masahiko Watanabe,Takahiro Hirabayashi,Takeshi Yagi, Cold Spring Harbor Laboratory, 2023/04/15
  • Double mutation of <i>claudin‐1</i> and <i>claudin‐3</i> causes alopecia in infant mice, Koya Suzuki,Kosuke Yamaga,Reitaro Tokumasu,Tatsuya Katsuno,Hiroo Tanaka,Shuhei Chiba,Takeshi Yagi,Ichiro Katayama,Atsushi Tamura,Hiroyuki Murota,Sachiko Tsukita, Annals of the New York Academy of Sciences, Wiley, Vol. 1523, No. 1, p. 51-61, 2023/03/31
  • Isoform requirement of clustered protocadherin for preventing neuronal apoptosis and neonatal lethality, Hiroaki Kobayashi,Kenji Takemoto,Makoto Sanbo,Masumi Hirabayashi,Takahiro Hirabayashi,Teruyoshi Hirayama,Hiroshi Kiyonari,Takaya Abe,Takeshi Yagi, iScience, Elsevier BV, Vol. 26, No. 1, p. 105766-105766, 2023/01
  • CTCF loss induces giant lamellar bodies in Purkinje cell dendrites., Teruyoshi Hirayama,Yuuki Kadooka,Etsuko Tarusawa,Sei Saitoh,Hisako Nakayama,Natsumi Hoshino,Soichiro Nakama,Takahiro Fukuishi,Yudai Kawanishi,Hiroki Umeshima,Koichi Tomita,Yumiko Yoshimura,Niels Galjart,Kouichi Hashimoto,Nobuhiko Ohno,Takeshi Yagi, Acta neuropathologica communications, Vol. 10, No. 1, p. 172-172, 2022/11/29
  • Early embryonic mutations reveal dynamics of somatic and germ cell lineages in mice., Arikuni Uchimura,Hirotaka Matsumoto,Yasunari Satoh,Yohei Minakuchi,Sayaka Wakayama,Teruhiko Wakayama,Mayumi Higuchi,Masakazu Hashimoto,Ryutaro Fukumura,Atsushi Toyoda,Yoichi Gondo,Takeshi Yagi, Genome research, Vol. 32, No. 5, p. 945-955, 2022/05
  • Development of FRET-based indicators for visualizing homophilic trans interaction of a clustered protocadherin., Takashi Kanadome,Natsumi Hoshino,Takeharu Nagai,Tomoki Matsuda,Takeshi Yagi, Scientific reports, Vol. 11, No. 1, p. 22237-22237, 2021/11/15
  • Suppression of DNA Double-Strand Break Formation by DNA Polymerase β in Active DNA Demethylation Is Required for Development of Hippocampal Pyramidal Neurons., Akiko Uyeda,Kohei Onishi,Teruyoshi Hirayama,Satoko Hattori,Tsuyoshi Miyakawa,Takeshi Yagi,Nobuhiko Yamamoto,Noriyuki Sugo, The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 40, No. 47, p. 9012-9027, 2020/11/18
  • Time-resolved neurotransmitter detection in mouse brain tissue using an artificial intelligence-nanogap., Yuki Komoto,Takahito Ohshiro,Takeshi Yoshida,Etsuko Tarusawa,Takeshi Yagi,Takashi Washio,Masateru Taniguchi, Scientific reports, Vol. 10, No. 1, p. 11244-11244, 2020/07/09
  • Dopamine D1 and muscarinic acetylcholine receptors in dorsal striatum are required for high speed running., Toru Nakamura,Luis Carl Rios,Takeshi Yagi,Toshikuni Sasaoka,Takashi Kitsukawa, Neuroscience research, Vol. 156, p. 50-57, 2020/07
  • Time-resolved neurotransmitter detection in mouse brain tissue using an artificial intelligence-nanogap., Komoto Y,Ohshiro T,Yoshida T,Tarusawa E,Yagi T,Washio T,Taniguchi M, Sci Rep., Vol. 10, No. 1, 2020/07
  • Pcdhβ deficiency affects hippocampal CA1 ensemble activity and contextual fear discrimination., Hirotaka Asai,Noriaki Ohkawa,Yoshito Saitoh,Khaled Ghandour,Emi Murayama,Hirofumi Nishizono,Mina Matsuo,Teruyoshi Hirayama,Ryosuke Kaneko,Shin-Ichi Muramatsu,Takeshi Yagi,Kaoru Inokuchi, Molecular brain, Vol. 13, No. 1, p. 7-7, 2020/01/20
  • Pcdhb deficiency affects hippocampal CA1 ensemble activity and contextual fear discrimination., Asai H,Ohkawa N,Saitoh Y,Ghandour K,Murayama E,Nishizono H,Matsuo M,Hirayama T,Kaneko R,Muramatsu S,Yagi T,Inokuchi K, Mol Brain, Vol. 13, No. 1, p. 7-7, 2020/01
  • Skilled Movements in Mice Require Inhibition of Corticospinal Axon Collateral Formation in the Spinal Cord by Semaphorin Signaling., Gu Z,Ueno M,Klinefelter K,Mamidi M,Yagi T,Yoshida Y, J Neuroscience, Vol. 39, No. 45, p. 8885-8899, 2019/11
  • Snf2h Drives Chromatin Remodeling to Prime Upper Layer Cortical Neuron Development, Matías Alvarez-Saavedra,Keqin Yan,Yves De Repentigny,Lukas E. Hashem,Nidhi Chaudary,Shihab Sarwar,Doo Yang,Ilya Ioshikhes,Rashmi Kothary,Teruyoshi Hirayama,Takeshi Yagi,David J. Picketts, Frontiers in Molecular Neuroscience, Frontiers Media SA, Vol. 12, 2019/10
  • Dysregulated protocadherin-pathway activity as an intrinsic defect in induced pluripotent stem cell-derived cortical interneurons from subjects with schizophrenia., Zhicheng Shao,Haneul Noh,Woong Bin Kim,Peiyan Ni,Christine Nguyen,Sarah E Cote,Elizabeth Noyes,Joyce Zhao,Teagan Parsons,James M Park,Kelvin Zheng,Joshua J Park,Joseph T Coyle,Daniel R Weinberger,Richard E Straub,Karen F Berman,Jose Apud,Dost Ongur,Bruce M Cohen,Donna L McPhie,Judith L Rapoport,Roy H Perlis,Thomas A Lanz,Hualin Simon Xi,Changhong Yin,Weihua Huang,Teruyoshi Hirayama,Emi Fukuda,Takeshi Yagi,Sulagna Ghosh,Kevin C Eggan,Hae-Young Kim,Leonard M Eisenberg,Alexander A Moghadam,Patric K Stanton,Jun-Hyeong Cho,Sangmi Chung, Nature neuroscience, Vol. 22, No. 2, p. 229-242, 2019/02
  • Dysregulated protocadherin-pathway activity as an intrinsic defect in induced pluripotent stem cell–derived cortical interneurons from subjects with schizophrenia, Zhicheng Shao,Haneul Noh,Woong Bin Kim,Peiyan Ni,Christine Nguyen,Sarah E. Cote,Elizabeth Noyes,Joyce Zhao,Teagan Parsons,James M. Park,Kelvin Zheng,Joshua J. Park,Joseph T. Coyle,Daniel R. Weinberger,Richard E. Straub,Karen F. Berman,Jose Apud,Dost Ongur,Bruce M. Cohen,Donna L. McPhie,Judith L. Rapoport,Roy H. Perlis,Thomas A. Lanz,Hualin Simon Xi,Changhong Yin,Weihua Huang,Teruyoshi Hirayama,Emi Fukuda,Takeshi Yagi,Sulagna Ghosh,Kevin C. Eggan,Hae-Young Kim,Leonard M. Eisenberg,Alexander A. Moghadam,Patric K. Stanton,Jun-Hyeong Cho,Sangmi Chung, Nature Neuroscience, Springer Science and Business Media LLC, Vol. 22, No. 2, p. 229-242, 2019/02
  • Snf2h Drives Chromatin Remodeling to Prime Upper Layer Cortical Neuron Development., Matías Alvarez-Saavedra,Keqin Yan,Yves De Repentigny,Lukas E Hashem,Nidhi Chaudary,Shihab Sarwar,Doo Yang,Ilya Ioshikhes,Rashmi Kothary,Teruyoshi Hirayama,Takeshi Yagi,David J Picketts, Frontiers in molecular neuroscience, Vol. 12, p. 243-243, 2019
  • Molecular diversity of clustered protocadherin-α required for sensory integration and short-term memory in mice, Tatsuya Yamagishi,Kohei Yoshitake,Daiki Kamatani,Kenji Watanabe,Hiroaki Tsukano,Ryuichi Hishida,Kuniyuki Takahashi,Sugata Takahashi,Arata Horii,Takeshi Yagi,Katsuei Shibuki, Scientific Reports, Springer Science and Business Media LLC, Vol. 8, No. 1, 2018/12
  • Molecular diversity of clustered protocadherin-α required for sensory integration and short-term memory in mice., Tatsuya Yamagishi,Kohei Yoshitake,Daiki Kamatani,Kenji Watanabe,Hiroaki Tsukano,Ryuichi Hishida,Kuniyuki Takahashi,Sugata Takahashi,Arata Horii,Takeshi Yagi,Katsuei Shibuki, Scientific reports, Vol. 8, No. 1, p. 9616-9616, 2018/06/25
  • ニューロンIDの可視化 クラスター型プロトカドヘリンの発現解析, 金子 涼輔,阿部 学,高鶴 裕介,渡辺 雅彦,崎村 建司,柳川 右千夫,八木 健, 生命科学系学会合同年次大会, 生命科学系学会合同年次大会運営事務局, Vol. 2017年度, p. [4LT08-1196)], 2017/12
  • Protocadherin-αC2 is required for diffuse projections of serotonergic axons., Shota Katori,Yukiko Noguchi-Katori,Atsushi Okayama,Yoshimi Kawamura,Wenshu Luo,Kenji Sakimura,Takahiro Hirabayashi,Takuji Iwasato,Takeshi Yagi, Scientific reports, Vol. 7, No. 1, p. 15908-15908, 2017/11/21
  • Protocadherin-alpha C2 is required for diffuse projections of serotonergic axons, Shota Katori,Yukiko Noguchi-Katori,Atsushi Okayama,Yoshimi Kawamura,Wenshu Luo,Kenji Sakimura,Takahiro Hirabayashi,Takuji Iwasato,Takeshi Yagi, SCIENTIFIC REPORTS, NATURE PUBLISHING GROUP, Vol. 7, No. 1, 2017/11
  • Regulation of clustered protocadherin genes in individual neurons., Teruyoshi Hirayama,Takeshi Yagi, Seminars in cell & developmental biology, Vol. 69, p. 122-130, 2017/09
  • Regulation of clustered protocadherin genes in individual neurons, Teruyoshi Hirayama,Takeshi Yagi, SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY, ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD, Vol. 69, p. 122-130, 2017/09
  • Genome Stability by DNA Polymerase β in Neural Progenitors Contributes to Neuronal Differentiation in Cortical Development., Kohei Onishi,Akiko Uyeda,Mitsuhiro Shida,Teruyoshi Hirayama,Takeshi Yagi,Nobuhiko Yamamoto,Noriyuki Sugo, The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 37, No. 35, p. 8444-8458, 2017/08/30
  • The methyltransferase SETDB1 regulates a large neuron-specific topological chromatin domain., Yan Jiang,Yong-Hwee Eddie Loh,Prashanth Rajarajan,Teruyoshi Hirayama,Will Liao,Bibi S Kassim,Behnam Javidfar,Brigham J Hartley,Lisa Kleofas,Royce B Park,Benoit Labonte,Seok-Man Ho,Sandhya Chandrasekaran,Catherine Do,Brianna R Ramirez,Cyril J Peter,Julia T C W,Brian M Safaie,Hirofumi Morishita,Panos Roussos,Eric J Nestler,Anne Schaefer,Benjamin Tycko,Kristen J Brennand,Takeshi Yagi,Li Shen,Schahram Akbarian, Nature genetics, Vol. 49, No. 8, p. 1239-1250, 2017/08
  • The methyltransferase SETDB1 regulates a large neuron-specific topological chromatin domain, Yan Jiang,Yong-Hwee Eddie Loh,Prashanth Rajarajan,Teruyoshi Hirayama,Will Liao,Bibi S. Kassim,Behnam Javidfar,Brigham J. Hartley,Lisa Kleofas,Royce B. Park,Benoit Labonte,Seok-Man Ho,Sandhya Chandrasekaran,Catherine Do,Brianna R. Ramirez,Cyril J. Peter,T. C. W. Julia,Brian M. Safaie,Hirofumi Morishita,Panos Roussos,Eric J. Nestler,Anne Schaefer,Benjamin Tycko,Kristen J. Brennand,Takeshi Yagi,Li Shen,Schahram Akbarian, NATURE GENETICS, NATURE PUBLISHING GROUP, Vol. 49, No. 8, p. 1239-+, 2017/08
  • Genome Stability by DNA Polymerase beta in Neural Progenitors Contributes to Neuronal Differentiation in Cortical Development, Kohei Onishi,Akiko Uyeda,Mitsuhiro Shida,Teruyoshi Hirayama,Takeshi Yagi,Nobuhiko Yamamoto,Noriyuki Sugo, JOURNAL OF NEUROSCIENCE, SOC NEUROSCIENCE, Vol. 37, No. 35, p. 8444-8458, 2017/08
  • Protein Tyrosine Phosphatase δ Mediates the Sema3A-Induced Cortical Basal Dendritic Arborization through the Activation of Fyn Tyrosine Kinase., Fumio Nakamura,Takako Okada,Maria Shishikura,Noriko Uetani,Masahiko Taniguchi,Takeshi Yagi,Yoichiro Iwakura,Toshio Ohshima,Yoshio Goshima,Stephen M Strittmatter, The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 37, No. 30, p. 7125-7139, 2017/07/26
  • Slow-Myofiber Commitment by Semaphorin 3A Secreted from Myogenic Stem Cells., Ryuichi Tatsumi,Takahiro Suzuki,Mai-Khoi Q Do,Yuki Ohya,Judy E Anderson,Ayumi Shibata,Mai Kawaguchi,Shunpei Ohya,Hideaki Ohtsubo,Wataru Mizunoya,Shoko Sawano,Yusuke Komiya,Riho Ichitsubo,Koichi Ojima,Shin-Ichiro Nishimatsu,Tsutomu Nohno,Yutaka Ohsawa,Yoshihide Sunada,Mako Nakamura,Mitsuhiro Furuse,Yoshihide Ikeuchi,Takanori Nishimura,Takeshi Yagi,Ronald E Allen, Stem cells (Dayton, Ohio), Vol. 35, No. 7, p. 1815-1834, 2017/07
  • Protein Tyrosine Phosphatase delta Mediates the Sema3A-Induced Cortical Basal Dendritic Arborization through the Activation of Fyn Tyrosine Kinase, Fumio Nakamura,Takako Okada,Maria Shishikura,Noriko Uetani,Masahiko Taniguchi,Takeshi Yagi,Yoichiro Iwakura,Toshio Ohshima,Yoshio Goshima,Stephen M. Strittmatter, JOURNAL OF NEUROSCIENCE, SOC NEUROSCIENCE, Vol. 37, No. 30, p. 7125-7139, 2017/07
  • Slow-Myofiber Commitment by Semaphorin 3A Secreted from Myogenic Stem Cells, Ryuichi Tatsumi,Takahiro Suzuki,Mai-Khoi Q. Do,Yuki Ohya,Judy E. Anderson,Ayumi Shibata,Mai Kawaguchi,Shunpei Ohya,Hideaki Ohtsubo,Wataru Mizunoya,Shoko Sawano,Yusuke Komiya,Riho Ichitsubo,Koichi Ojima,Shin-ichiro Nishimatsu,Tsutomu Nohno,Yutaka Ohsawa,Yoshihide Sunada,Mako Nakamura,Mitsuhiro Furuse,Yoshihide Ikeuchi,Takanori Nishimura,Takeshi Yagi,Ronald E. Allen, STEM CELLS, Wiley, Vol. 35, No. 7, p. 1815-1834, 2017/07
  • Learning new sequential stepping patterns requires striatal plasticity during the earliest phase of acquisition., Toru Nakamura,Masatoshi Nagata,Takeshi Yagi,Ann M Graybiel,Tetsuo Yamamori,Takashi Kitsukawa, The European journal of neuroscience, Vol. 45, No. 7, p. 901-911, 2017/04
  • Learning New Sequential Stepping Patterns Requires Striatal Plasticity during the Earliest Phase of Acquisition, Nakamura T,Nagata M,Yagi T,Graybiel AM,Yamamori T,Kitsukawa T, The European journal of neuroscience, Vol. 45, No. 7, p. 901-911, 2017/04
  • Clustered protocadherin are required for building functional neural circuits., Hasegawa S,Kobayashi H,Kumagai M,Nishimaru H,Tarusawa E,Kanda H,Sanbo M,Yoshimura Y,Hirabayashi M,Hirabayashi T,Yagi T, Frontiers in Molecular Neuroscience, Frontiers Media SA, Vol. 10:, 2017/04
  • Clustered Protocadherins Are Required for Building Functional Neural Circuits., Sonoko Hasegawa,Hiroaki Kobayashi,Makiko Kumagai,Hiroshi Nishimaru,Etsuko Tarusawa,Hiro Kanda,Makoto Sanbo,Yumiko Yoshimura,Masumi Hirabayashi,Takahiro Hirabayashi,Takeshi Yagi, Frontiers in molecular neuroscience, Vol. 10, p. 114-114, 2017
  • Establishment of high reciprocal connectivity between clonal cortical neurons is regulated by the Dnmt3b DNA methyltransferase and clustered protocadherins., Etsuko Tarusawa,Makoto Sanbo,Atsushi Okayama,Toshio Miyashita,Takashi Kitsukawa,Teruyoshi Hirayama,Takahiro Hirabayashi,Sonoko Hasegawa,Ryosuke Kaneko,Shunsuke Toyoda,Toshihiro Kobayashi,Megumi Kato-Itoh,Hiromitsu Nakauchi,Masumi Hirabayashi,Takeshi Yagi,Yumiko Yoshimura, BMC biology, Vol. 14, No. 1, p. 103-103, 2016/12/02
  • Establishment of high reciprocal connectivity between clonal cortical neurons is regulated by the <I> Dnmt3b</I> DNA methyltransferase and clustered protocadherins., Tarusawa E,Sanbo M,Okayama A,Miyashita T,Kitsukawa T,Hirayama T,Hirabayashi T,Hasegawa S,Kaneko R,Toyoda S,Kobayashi T,Kato-Itoh M,Nakauchi H,Hirabayashi M,Yagi T,Yoshimura Y, BMC Biology, Vol. 14, No. 1, p. 103.-103, 2016/12/02
  • Distinct and cooperative functions for the <i>protocadherin</i>-α, -β and -γ clusters in neuronal survival and axon targeting., Hasegawa S,Kumagai M,Hagihara M,Nishimaru H,Hirano K,Kaneko R,Okayama A,Hirayama T,Sanbo M,Hirabayashi M,Watanabe M,Hirabayashi T,Yagi T, Frontiers in Molecular Neuroscience, Vol. 9:, p. 155.-155, 2016/12
  • Transgenic rat model of childhood-onset dermatitis by overexpressing telomerase reverse transcriptase (TERT)., Ryosuke Kaneko,Atsuko Sato,Shun Hamada,Takeshi Yagi,Ichiro Ohsawa,Mamitaro Ohtsuki,Eiji Kobayashi,Masumi Hirabayashi,Takashi Murakami, Transgenic research, Vol. 25, No. 4, p. 413-24, 2016/08
  • Transgenic rat model of childhood-onset dermatitis by overexpressing telomerase reverse transcriptase (TERT)., Kaneko R,Sato A,Hamada S,Yagi T,Ohsawa I,Ohtsuki M,Kobayashi E,Hirabayashi M,Murakami T, Transgenic Research, Vol. 25, No. 4, p. 413-424., 2016/08
  • Distinct and Cooperative Functions for the Protocadherin-α, -β and -γ Clusters in Neuronal Survival and Axon Targeting., Sonoko Hasegawa,Makiko Kumagai,Mitsue Hagihara,Hiroshi Nishimaru,Keizo Hirano,Ryosuke Kaneko,Atsushi Okayama,Teruyoshi Hirayama,Makoto Sanbo,Masumi Hirabayashi,Masahiko Watanabe,Takahiro Hirabayashi,Takeshi Yagi, Frontiers in molecular neuroscience, Vol. 9, p. 155-155, 2016
  • ニューロンIDの可視化 クラスター型プロトカドヘリンの発現解析, 金子 涼輔,阿部 学,高鶴 裕介,De Zeeuw Chris,渡辺 雅彦,崎村 建司,柳川 右千夫,八木 健, 日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, (公社)日本生化学会, Vol. 88回・38回, p. [1LBA115]-[1LBA115], 2015/12
  • The transfer and transformation of collective network information in gene-matched networks., Takashi Kitsukawa,Takeshi Yagi, Scientific reports, Vol. 5, p. 14984-14984, 2015/10/09
  • Genetic Mapping in Mice Reveals the Involvement of Pcdh9 in Long-Term Social and Object Recognition and Sensorimotor Development., Hilgo Bruining,Asuka Matsui,Asami Oguro-Ando,René S Kahn,Heleen M Van't Spijker,Guus Akkermans,Oliver Stiedl,Herman van Engeland,Bastijn Koopmans,Hein A van Lith,Hugo Oppelaar,Liselotte Tieland,Lourens J Nonkes,Takeshi Yagi,Ryosuke Kaneko,J Peter H Burbach,Nobuhiko Yamamoto,Martien J Kas, Biological psychiatry, Vol. 78, No. 7, p. 485-95, 2015/10/01
  • The transfer and transformation of collective network information in gene-matched networks., Kitsukawa T,Yagi T, Scientific Reports, Vol. 5, 2015/09
  • Germline mutation rates and the long-term phenotypic effects of mutation accumulation in wild-type laboratory mice and mutator mice., Arikuni Uchimura,Mayumi Higuchi,Yohei Minakuchi,Mizuki Ohno,Atsushi Toyoda,Asao Fujiyama,Ikuo Miura,Shigeharu Wakana,Jo Nishino,Takeshi Yagi, Genome research, Vol. 25, No. 8, p. 1125-34, 2015/08
  • Population genetics and Brain evolution, Arikuni Uchimura,Takeshi Yagi, 中外医学社, Vol. 33, No. 8, p. 909-911, 2015/08
  • Germline mutation rates and the long-term phenotypic effects of mutation accumulation in wild-type laboratory mice and mutator mice., Arikuni Uchimura,Mayumi Higuchi,Yohei Minakuchi,Mizuki Ohno,Atsushi Toyoda,Asao Fujiyama,Ikuo Miura,Shigeharu Wakana,Jo Nishino,Takeshi Yagi, Genome research, Vol. 25, No. 8, p. 1125-1134, 2015/08
  • Impaired clustered protocadherin-α leads to aggregated retinogeniculate terminals and impaired visual acuity in mice., Reiko Meguro,Ryuichi Hishida,Hiroaki Tsukano,Kohei Yoshitake,Ryota Imamura,Manavu Tohmi,Takashi Kitsukawa,Takahiro Hirabayashi,Takeshi Yagi,Hirohide Takebayashi,Katsuei Shibuki, Journal of neurochemistry, Vol. 133, No. 1, p. 66-72, 2015/04
  • Impaired clustered protocadherin-α leads to aggregated retinogeniculate terminals and impaired visual acuity in mice., Meguro R,Hishida R,Tsukano H,Yoshitake K,Imamura R,Tohmi M,Kitsukawa T,Hirabayashi T,Yagi T,Takebayashi H,Shibuki K, Journal of neurochemistry, Vol. 133, No. 1, p. 66-72, 2015/04
  • Genetic Mapping in Mice Reveals the Involvement of Pcdh9 in Long-Term Social and Object Recognition and Sensorimotor Development, Hilgo Bruining,Asuka Matsui,Asami Oguro-Ando,Rene S. Kahn,Heleen M. van't Spijker,Guus Akkermans,Oliver Stiedl,Herman van Engeland,Bastijn Koopmans,Hein A. van Lith,Hugo Oppelaar,Liselotte Tieland,Lourens J. Nonkes,Takeshi Yagi,Ryosuke Kaneko,J. Peter H. Burbach,Nobuhiko Yamamoto,Martien J. Kas, BIOLOGICAL PSYCHIATRY, ELSEVIER SCIENCE INC, Vol. 78, No. 7, p. 485-495, 2015/02
  • Expansion of stochastic expression repertoire by tandem duplication in mouse Protocadherin-α cluster., Kaneko R,Abe M,Hirabayashi T,Uchimura A,Sakimura K,Yanagawa Y,Yagi T, Scientific reports, Vol. 4, 2014/09
  • Protocadherins in neurological diseases., Hirabayashi T,Yagi T, Adv Neurobiol., Vol. 8, p. 293-314, 2014/08
  • Developmental epigenetic modification regulates stochastic expression of clustered protocadherin genes, generating single neuron diversity., Toyoda S,Kawaguchi M,Kobayashi T,Tarusawa E,Toyama T,Okano M,Oda M,Nakauchi H,Yoshimura Y,Sanbo M,Hirabayashi M,Hirayama T,Hirabayashi T,Yagi T, Neuron, Elsevier BV, Vol. 82, No. 1, p. 94-108, 2014/04
  • Protocadherins in neurological diseases., Takahiro Hirabayashi,Takeshi Yagi, Advances in neurobiology, Vol. 8, p. 293-314, 2014
  • Visual map shifts based on whisker-guided cues in the young mouse visual cortex., Yoshitake K,Tsukano H,Tohmi M,Komagata S,Hishida R,Yagi T,Shibuki K, Cell Reports, Vol. 5, p. 1365-1374, 2013/12
  • Genetic basis of neuronal individuality in the mammalian brain, Yagi T, Journal of Neurogenetics, Vol. 97, p. 97-105, 2013/09
  • Clustered protocadherins and neuronal diversity., Hirayama T,Yagi T, Progress in molecular biology and translational science, Vol. 116, p. 145-167, 2013
  • Constitutively expressed Protocadherin-α regulates the coalescence and elimination of homotypic olfactory axons through its cytoplasmic region, Sonoko Hasegawa,Takahiro Hirabayashi,Takahiko Kondo,Ken Inoue,Shigeyuki Esumi,Atsushi Okayama,Shun Hamada,Takeshi Yagi, Frontiers in Molecular Neuroscience, Vol. 5, 2012/10
  • CTCF Is Required for Neural Development and Stochastic Expression of Clustered Pcdh Genes in Neurons, Teruyoshi Hirayama,Etsuko Tarusawa,Yumiko Yoshimura,Niels Galjart,Takeshi Yagi, CELL REPORTS, CELL PRESS, Vol. 2, No. 2, p. 345-357, 2012/08
  • Restoration of contralateral representation in the mouse somatosensory cortex after crossing nerve transfer, Haruyoshi Yamashita,Shanlin Chen,Seiji Komagata,Ryuichi Hishida,Takuji Iwasato,Shigeyoshi Itohara,Takeshi Yagi,Naoto Endo,Minoru Shibata,Katsuei Shibuki, PLoS ONE, Vol. 7, No. 4, 2012/04
  • Molecular codes for neuronal individuality and cell assembly in the brain, Takeshi Yagi, Frontiers in Molecular Neuroscience, No. MARCH, p. 1-31, 2012/04
  • The transformation suppressor gene Reck is required for postaxial patterning in mouse forelimbs, Mako Yamamoto,Tomoko Matsuzaki,Rei Takahashi,Eijiro Adachi,Yasuhiro Maeda,Sachiyo Yamaguchi,Hitoshi Kitayama,Michiko Echizenya,Yoko Morioka,David B. Alexander,Takeshi Yagi,Shigeyoshi Itohara,Takashi Nakamura,Haruhiko Akiyama,Makoto Noda, Biology Open, Company of Biologists Ltd, Vol. 1, No. 5, p. 458-466, 2012/03
  • Mutant mice for CNR/protocadherin genes, Katori, S,Yagi, T, 2011/11
  • Identification of the cluster control region for the Protocadherin-b genes located beyond the Protocadherin-g cluster., Yokota S,Hirayama T,Hirano K,Kaneko R,Toyoda S,Kawamura Y,Hirabayashi M,Hirabayashi T,Yagi T, Journal of Biological Chemistry, Vol. 286, No. 36, p. 31885-31895., 2011/09
  • A novel instrumented multipeg running wheel system, Step-Wheel, for monitoring and controlling complex sequential stepping in mice., Kitsukawa T,Nagata M,Yanagihara D,Tomioka R,Utsumi H,Kubota Y,Yagi T,Graybiel AM,Yamamori T, Journal of Neurophysiology, 2011/07
  • Selective ablation of histamine H1 receptor-expressing neurons in the paraventricular nucleus of the hypothalamus to study their role in the regulation of food intake, Shuhei Horio,Shuji Kitaike,Tetsuya Shiuchi,Yasuhiko Minokoshi,Makoto Sanbo,Takahiro Hirabayashi,Takeshi Yagi,Nobuyuki Kai,Kazuto Kobayashi,Takashi Ueyama,Hiroyuki Fukui, NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, Vol. 71, p. E162-E162, 2011
  • Establishment of rat embryonic stem cell lines that can participate Into germline chimerae at high efficiency., Hirabayashi M,Kato M,Kobayashi T,Sanbo M,Yagi T,Hochi S,Nakauchi H, Molecular Reproduction and Development, Vol. 77, No. 2, 2009/11
  • Total expression and dual gene-regulatory mechanisms maintained in deletions and duplications of the Protocadherin-alpha cluster., Noguchi Y,Hirabayashi T,Katori S,Kawamura Y,Sanbo M,Hirabayashi M,Kiyonari H,Nakao K,Uchimura A,Yagi T, Journal of Biological Chemistry, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 284, No. 46, p. 32002-32014, 2009/11
  • The chromosomal constitution of postmitotic neurons, assessed by neuronal nuclear transfer into oocytes and in ES cell lines derived from them., Osada T,Kakazu N,Watanabe M,Yamane H,Yagi T, Cytogenetic Genome Research, 2009/07
  • Kinase-dead knock-in mouse reveals an essential role of kinase activity of Ca2+/calmodulin-dependent protein kinase IIalpha in dendritic spine enlargement, long-term potentiation, and learning., Yoko Yamagata,Shizuka Kobayashi,Tatsuya Umeda,Akihiro Inoue,Hiroyuki Sakagami,Masahiro Fukaya,Masahiko Watanabe,Nobuhiko Hatanaka,Masako Totsuka,Takeshi Yagi,Kunihiko Obata,Keiji Imoto,Yuchio Yanagawa,Toshiya Manabe,Shigeo Okabe, The Journal of neuroscience : the official journal of the Society for Neuroscience, SOC NEUROSCIENCE, Vol. 29, No. 23, p. 7607-18, 2009/06/10
  • Decreased expression of Fyn protein and disbalanced alternative splicing patterns in platelets from patients with schizophrenia., Hattori K,Fukuzako H,Hashiguchi T,Hamada S,Murata Y,Isosaka T,Yuasa S,Yagi T, Psychiatry Research, ELSEVIER IRELAND LTD, Vol. 168, No. 2, p. 119-128, 2009/06
  • Protocadherin-a family is required for serotonergic projections to appropriately innervate target brain areas., Katori S,Hamada S,Noguchi Y,Fukuda E,Yamamoto T,Yamamoto H,Hasegawa S,Yagi T, The Journal of Neuroscience, SOC NEUROSCIENCE, Vol. 29, No. 29, p. 9137-9147, 2009/05
  • Kinase-dead knock-in mouse revealed an essential role of CaMKIIa kinase activity in dendritic spine enlargement, LTP and learning., Yamagata Y,Kobayashi S,Umeda T,Inoue A,Sakagami H,Fukaya M,Watanabe M,Hatanaka N,Totsuka M,Yagi T,Obata K,Imoto K,Yanagawa Y,Manabe T,Okabe S, The Journal of Neuroscience, 2009/04
  • Kinase activity of CaMKII alpha is essential for structural, functional and behavioral expression of synaptic memory, Yamagata Yoko,Kobayashi Shizuka,Umeda Tatsuya,Inoue Akihiro,Sakagami Hiroyuki,Fukaya Masahiro,Watanabe Masahiko,Hatanaka Nobuhiko,Totsuka Masako,Yagi Takeshi,Obata Kunihiko,Imoto Keiji,Yanagawa Yuchio,Manabe Toshiya,Okabe Shigeo, NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, Vol. 65, p. S144-S144, 2009
  • Rapid identification of virus-carrying mosquitoes using reverse transcription-loop-mediated isothermal amplification., Perera N,Aonuma H,Yoshimura A,Teramoto T,Iseki H,Nelson B,Igarashi I,Yagi T,Fukumoto S,Kanuka H, Journal of Virological Methods, 2009/01
  • 遺伝子からみた脳の進化のシナリオ, 八木 健, 生体の科学, 2009/01
  • Expressional levels of Protocadherin-a transcripts are decreased by nonsense-mediated mRNA decay with frameshift mutations and by high DNA methylation in their promoter regions., Kaneko R,Kawaguchi M,Toyama T,Yagi T, Gene, ELSEVIER SCIENCE BV, Vol. 430, No. 1-2, p. 86-94, 2009/01
  • DNA polymerase delta is required for early mammalian embryogenesis., Uchimura A,Hidaka Y,Hirabayashi T,Hirabayashi M,Yagi T, PLoS ONE, PUBLIC LIBRARY SCIENCE, Vol. 4, No. 1, 2009/01
  • NORADRENERGIC EXCITATION OF A SUBPOPULATION OF GABAergic CELLS IN THE BASOLATERAL AMYGDALA VIA BOTH ACTIVATION OF NONSELECTIVE CATIONIC CONDUCTANCE AND SUPPRESSION OF RESTING K+ CONDUCTANCE: A STUDY USING GLUTAMATE DECARBOXYLASE 67-GREEN FLUORESCENT PROTEIN KNOCK-IN MICE, K. Kaneko,N. Tamamaki,H. Owada,T. Kakizaki,N. Kume,M. Totsuka,T. Yamamoto,H. Yawo,T. Yagi,K. Obata,Y. Yanagawa, NEUROSCIENCE, PERGAMON-ELSEVIER SCIENCE LTD, Vol. 157, No. 4, p. 781-797, 2008/12
  • Rapid identification of Plasmodium-carrying mosquitoes using loop-mediated isothermal amplification., Aonuma H,Suzuki M,Iseki H,Perera N,Nelson B,Igarashi I,Yagi T,Kanuka H,Fukumoto S, Biochemical and Biophysical Research Communications, Vol. 376, No. 4, p. 671-6, 2008/11
  • Down-regulation of protocadherin-a A isoforms in mice changes contextual fear conditioning and spatial working memory., Fukuda E,Hamada S,Hasegawa S,Katori S,Sanbo M,Miyakawa T,Yamamoto T,Yamamoto H,Hirabayashi T,Yagi T, European Journal of Neuroscience, WILEY-BLACKWELL, Vol. 28, No. 7, p. 1362-1376, 2008/09
  • Activation of Fyn tyrosine kinase in the mouse dorsal hippocampus is essential for contexual conditioning., Isosaka T,Hattori K,Kida S,Kohno T,Nakazawa T,Yamamoto T,Yagi T,Yuasa S, European Journal of Neuroscience, 5, Vol. 28, p. 973-981, 2008/08
  • Clustered protocadherin family., Yagi T, Development and Growth Differentiation, BLACKWELL PUBLISHING, Vol. 50, p. S131-S140, 2008/06
  • クラスター型プロトカドヘリンファミリーー多様性創出機構とその機能解明に向けて, 平山晃斉,長谷川園子,八木 健, 蛋白質 核酸 酵素, 2008/04
  • The protocadherin-a family is involved in axonal coalescence of olfactory sensory neurons into glomeruli of the olfactory bulb in mouse., Hasegawa S,Hamada S,Kumode Y,Esumi S,Katori S,Fukuda E,Uchiyama Y,Hirabayashi T,Mombearts P,Yagi T, Molecular and Cellular Neuroscience, ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 38, No. 1, p. 66-79, 2008/04
  • [Clustered protocadherin family]., Hirayama T,Hasegawa S,Yagi T, Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, Vol. 53, No. 4 Suppl, p. 358-364, 2008/03
  • Relationship between DNA methylation states and transcription of individual isoforms encoded by the protocadherin-alpha gene cluster., Kawaguchi M,Toyama T,Kaneko R,Hirayama T,Kawamura Y,Yagi T, Journal of Biological Chemistry, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 283, No. 18, p. 12064-12075, 2008/03
  • Protocadherin family: diversity, structure, and function., Morishita, H,Yagi, T, Curr Opin Cell Biol, CURRENT BIOLOGY LTD, Vol. 19, No. 5, p. 584-592, 2007/10
  • Mouse liaison for integrative brain research, Aiba, A,Inokuchi, K,Ishida, Y,Itohara, S,Kobayashi, K,Masu, M,Mishina, M,Miyakawa, T,Mori, H,Nakao, K,Obata, Y,Sakimura, K,Shiroishi, T,Wada, K,Yagi, T, Neurosci Res, Vol. 58, No. 2, p. 103-104, 2007/06
  • Restoration of FcRgamma/Fyn signaling repairs central nervous system demyelination., Seiwa C,Yamamoto M,Tanaka K,Fukutake M,Ueki T,Takeda S,Sakai R,Ishige A,Watanabe K,Akita M,Yagi T,Tanaka K,Asou H, J Neurosci Res., 2007/02
  • Interactions between Plexin-A2, Plexin-A4, and Semaphorin 6A Control Lamina-Restricted Projection of Hippocampal Mossy Fibers., Suto F,Tsuboi M,Kamiya H,Mizuno H,Kiyama Y,Komai S,Shimizu M,Sanbo M,Yagi T,Hiromi Y,Chedotal A,Mitchell KJ,Manabe T,Fujisawa H, Neuron, Vol. 53, No. 4, p. 535-47, 2007/02
  • Split single cell RT-PCR analysis of Purkinje cells., Esumi S,Kaneko R,Kawamura Y,Yagi T, Nature Protocols, NATURE PUBLISHING GROUP, Vol. 1, No. 4, p. 2143-2151, 2006/12
  • Structure of the CNR/Protocadherin-alpha first cadherin domain reveals diversity across cadherin families., Morishita H,Umitsu M,Murata Y,Shibata N,Udaka K,Higuchi Y,Akutsu H,Yamaguchi T,Yagi T,Ikegami T, J Biol Chem, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 281, No. 44, p. 33650-33663, 2006/11
  • Neuronal genomics using mouse cloning with the single neuronal nucleus., Osada T,Yagi T, Current Genomics, 2006/10
  • カドヘリンの分子進化, 八木 健, 生体の科学, 2006/10
  • Allelic gene regulation of protocadherin-α and -γ clusters involving both monoallelic and biallelic expression in single Purkinje cells., Kaneko R,Kato H,Kawamura Y,Esumi S,Hirayama T,Hirabayashi T,Yagi T, J Biol Chem, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 281, No. 41, p. 30551-30560, 2006/10
  • Embryonic stem cell-derived neuron models of Parkinson's disease exhibit delayed neuronal death., Yamashita H,Nakamura T,Takahashi T,Nagano Y,Hiji M,Hirabayashi T,Amano T,Yagi T,Sakai N,Kohriyama T,Matsumoto M, J Neurochem, 2006/09
  • Absence of leukotriene B4 receptor 1 confers resistance to airway hyperresponsiveness and Th2 type immune responses., Terawaki K,Yokomizo T,Nagase T,Toda A,Taniguchi M,Hashizume K,Yagi T,Shimizu T, J Immunol, 2006/08
  • Fyn kinase-mediated phosphorylation of NMDA receptor NR2B subunit at Tyr1472 is essential for maintenance of neuropathic pain., Abe T,Matsumura S,Katano T,Mabuchi T,Takagi K,Li Xu,Yamamoto A,Hattori K,Yagi T,Watanabe M,Nakazawa T,Yamamoto T,Mishina M,Nakai Y,Ito S, Eur J Neurosci., 2006/08
  • Fyn-induced phosphorylation of beta-adducin at tyrosine 489 and its role in their subcellular localization., Gotoh H,Okumura N,Yagi T,Okumura A,Shima T,Nagai K, Biochem Biophys Res Commun., ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 346, No. 2, p. 600-605, 2006/08
  • Protocadherins: classification, structures and functions, Shun Hamada,Takeshi Yagi, SEIKAGAKU, JAPANESE BIOCHEMICAL SOC, Vol. 78, No. 7, p. 662-671, 2006/07
  • ミエリン化による神経軸索の成熟化と膜蛋白質の局在変化, 森下博文,八木健, 生体の科学, 2006/06
  • The role and expression of the protocadherin-alpha clusters in the CNS., Hirayama T,Yagi T, Curr Opin Neurobiol., CURRENT BIOLOGY LTD, Vol. 16, No. 3, p. 336-342, 2006/06
  • Regulation of dendritic branching and spine maturation by semaphorin3A-Fyn signaling., Morita A,Yamashita N,Sasaki Y,Uchida Y,Nakajima O,Nakamura F,Yagi T,Taniguchi M,Usui H,Katoh-Semba R,Takei K,Goshima Y, J Neurosci, Vol. 26, p. 2971-2980, 2006/04
  • 行動を支配する遺伝子は環境しだい, 八木健, 脳と心のしくみ、ニュートン, 2006/04
  • 細胞内シグナル伝達系ー高次脳機能の制御, 湯浅茂樹,服部功太郎,甲斐信行,中平英子,伊早坂智子,八木健, 先進脳神経科学, 培風館, 2006/03
  • Fyn is required for haloperidol-induced catalepsy in mice., Hattori K,Uchino S,Isosaka T,Maekawa M,Iyo M,Sato T,Kohsaka S,Yagi T,Yuasa S, J Biol Chem., AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 281, No. 11, p. 7129-7135, 2006/03
  • Altered gene expression in the subdivisions of the amygdala of Fyn-deficient mice as revealed by laser capture microdissection and mKIAA cDNA array analysis., Kai N,Iwase K,Imai K,Nakahira E,Soma M,Ohtsuka S,Yagi T,Kobayashi K,Koga H,Takiguchi M,Yuasa S, Brain Res., Vol. 1073-1074, p. 60-70, 2006/02
  • Predominant expression of rTERTb, an inactive TERT variant, in the adult rat brain., Kaneko R,Esumi S,Yagi T,Hirabayashi T, Protein Pept Lett., 1, Vol. 13, p. 59-65, 2006/02
  • 発達障害仮説における大脳皮質形成関連遺伝子の意義, 服部功太郎,伊早坂智子,湯浅茂樹,八木健, 脳と精神の医学, Vol. 17, No. 1, p. 65-72, 2006/01
  • Evaluation of somatic alterations of Pcdh-αtranscripts in the brain by cDNA analysis without PCR., Hirayama T,Sasaki A,Yagi T, Genes to Cells, BLACKWELL PUBLISHING, Vol. 11, No. 1, p. 95-97, 2006/01
  • NMDA-receptor proteins are upregulated in the hippocampus of post-natal heterozygous reeler mice., Isosaka T,Hattori K,Yagi T, Brain Res., ELSEVIER SCIENCE BV, Vol. 1073, p. 11-19, 2006/01
  • Developmental pluripotency of the nuclei of neurons in the cerebral cortex of juvenile mice., Osada T,Tamamaki N,Song S-Y,Kakazu N,Yamazaki Y,Makino H,Sasaki A,Hirayama T,Hamada S,Nave K-A,Yanagimachi R,Yagi T, J Neurosci, Vol. 25, No. 37, p. 8368-8374, 2005/09
  • Novel function of neuronal PAS domain protein 1 in erythropoietin expression in neuronal cells., Ohsawa S,Hamada S,Kakinuma Y,Yagi T,Miura M, J Neurosci Res, 2005/05
  • Fc{varepsilon}RI-mediated mast cell degranulation requires calcium-independent microtubule-dependent translocation of granules to the plasma membrane., Nishida K,Yamasaki S,Ito Y,Kabu K,Hattori K,Tezuka T,Nishizumi H,Kitamura D,Goitsuka R,Geha RS,Yamamoto T,Yagi T,Hirano T, J Cell Biol, 2005/05
  • Molecular Evolution of Cadherin-Related Neuronal Receptor/Protocadherinα (CNR/Pcdhα) Gene Cluster in Mus musculus Subspecies, Taguchi Y,Koide T,Shiroishi T,Yagi T, Molecular Biology and Evolution, OXFORD UNIV PRESS, Vol. 22, No. 6, p. 1433-1443, 2005/04
  • Mouse embryos and chimera cloned from neural cells in the postnatal cerebral cortex, Hatsune Makino,Yukiko Yamazaki,Takahiro Hirabayashi,Ryosuke Kaneko,Shun Hamada,Yoshimi Kawamura,Tomoharu Osada,Ryuzo Yanagimachi,Takeshi Yagi, Cloning and Stem Cells, 1, Vol. 7, No. 1, p. 45-61, 2005/03
  • Absence of leukotriene B4 receptor 1 confers resistance to airway hyperresponsiveness and Th2 type immune responses., Terawaki K,Yokomizo T,Nagase T,Toda A,Taniguchi M,Hashizume K,Yagi T,Shimizu T, J Immunol, Vol. 175, p. 4217-4225, 2005/02
  • 神経系における多様化膜分子群：CNR/プロトカドヘリンファミリー, 村田陽二,八木健, 神経研究の進歩, 医学書院, Vol. 49, No. 1, p. 115-127, 2005/02
  • Fruit fly as a model of insect vector, Aonuma H,Yagi T,Miura M,Schneider D,Kanuka H, Medical Entomology and Zoology, The Japan Society of Medical Entomology and Zoology, Vol. 56, p. 64-64, 2005
  • Ｉｎａｂａラット：疾患発症時期がヒトと類似しているアトピー性皮膚炎モデルトランスジェニックラット, 金子 涼輔,加藤 めぐみ,石川 綾子,平林 敬浩,濱田 俊,八木 健,平林 真澄, 日本疾患モデル学会記録, 公益社団法人 日本実験動物学会, Vol. 21, p. 22-26, 2005
  • Letter to the Editor: 1H, 13C and 15N resonance assignments of the first cadherin domain of cadherin-related neuronal receptor (CNR)/protocadherin α [3], Umitsu M,Morishita H,Murata Y,Udaka K,Akutsu H,Yagi T,Ikegami T, Journal of Biomolecular NMR, Vol. 31, No. 4, p. 365-366, 2005
  • Monoallelic yet combinatorial expression of variable exons of the CNR/Protocadherin-a gene cluster in single neurons, Esumi S,Kakazu N,Taguchi Y,Hirayama T,Sasaki A,Hirabayashi T,Koide T,Kitsukawa T,Hamada S,Yagi T, Nature Genet, NATURE PUBLISHING GROUP, Vol. 37, No. 2, p. 171-176, 2005/01
  • Plexin-A4 Mediates Axon-Repulsive Activities of Both Secreted and Transmembrane Semphorins and Play Roles in Nerve Fiber Guidance, Sudo F,Ito K,Uemura M,Shimizu M,Shinkawa Y,Sanbo M,Shinoda T,Tsuboi M,Takashima S,Yagi T,Fujisawa H, J Neurosci., Vol. 25, No. 14, p. 3628-3637, 2004/12
  • CNR/Pcdh alpha family in subplate neurons, and developing cortical connectivity, H Morishita,Y Murata,S Esumi,S Hamada,T Yagi, NEUROREPORT, LIPPINCOTT WILLIAMS & WILKINS, Vol. 15, No. 17, p. 2595-2599, 2004/12
  • Myelination triggers local loss of axonal CNR/protocadherin alpha family protein expression, H Morishita,M Kawaguchi,Y Murata,C Seiwa,S Hamada,H Asou,T Yagi, EUROPEAN JOURNAL OF NEUROSCIENCE, BLACKWELL PUBLISHING LTD, Vol. 20, No. 11, p. 2843-2847, 2004/12
  • Factors affecting production of transgenic rats by ICSI-mediated DNA transfer: Effects of sonication and freeze-thawing of spermatozoa, rat strains for sperm and oocyte donors, and different constructs of exogenous DNA, Hirabayashi M,Kato M,Ishikawa A,Kaneko R,Yagi T,Hochi S, Mol Reprod Dev, Vol. 70, No. 4, p. 422-428., 2004/11
  • Exposure to hexanal odor induces extraordinary Fos expression in the medial preoptic area and amygdala of Fyn tyrosine kinase-deficient mice, K Hamaguchi-Hamada,S Hamada,T Yagi, MOLECULAR BRAIN RESEARCH, ELSEVIER SCIENCE BV, Vol. 130, No. 1-2, p. 187-190, 2004/11
  • Production of transgenic rats by ooplasmic injection of spermatogenic cells exposed to exogenous DNA: A preliminary study., Kato M,Ishikawa A,Kaneko R,Yagi T,Hochi S,Hirabayashi M, Molecular Reproduction and Development, Vol. 69, No. 2, p. 153-158., 2004/10
  • Coordination of trigeminal axon navigation and patterning with tooth organ formation: epithelial-mesenchymal interactions, and epithelial Wnt4 and Tgfbeta1 regulate semaphorin 3a expression in the dental mesenchyme, Kettunen P,Loes, S,Furmanek T,Field K,Kvinnsland IH,Behar O,Yagi T,Fujisawa H,Vainio S,Taguchi M,Luukko K, Development, 2004/09
  • Reelinと統合失調症, 服部功太郎,伊早坂智子,八木健, Schizophrenia Fronteir, 2004/08
  • Negative and positive effects of an IAP-LTR on nearby Pcda alpha gene expression in the central nervous system and neuroblastoma cell lines, H Sugino,T Toyama,Y Taguchi,S Esumi,M Miyazaki,T Yagi, GENE, ELSEVIER SCIENCE BV, Vol. 337, p. 91-103, 2004/08
  • Correlation between semaphorin3A-induced facilitation of axonal transport and local activation of a translation initiation factor eukaryotic translation initiation factor 4E, CX Li,Y Sasaki,K Takei,H Yamamoto,M Shouji,Y Sugiyama,T Kawakami,F Nakamura,T Yagi,T Ohshima,Y Goshima, JOURNAL OF NEUROSCIENCE, SOC NEUROSCIENCE, Vol. 24, No. 27, p. 6161-6170, 2004/07
  • A Novel Function of Neuronal PAS Domain Protein 1 (NPAS1) in Erythropoietin Expression in Neuronal Cells, Ohsawa S,Hamada S,Kakinuma Y,Yagi T,Miura M, J. Neurosci. Res., 2004/07
  • Erratum: Cadherin-related neuronal receptor 1 (CNR1) has cell adhesion activity with β1 integrin mediated through the RGD site of CNR1 (Experimental Cell Research (2004) 294 (494-508) DOI: 10.1016/j.yexcr.2003.11. 019), Tetsuji Mutoh,Shun Hamada,Kouji Senzaki,Yoji Murata,Takeshi Yagi, Experimental Cell Research, Academic Press Inc., Vol. 297, No. 1, 2004/07/01
  • Identification and characterization of coding single-nucleotide polymorphisms within human protocadherin-α and –β gene clusters, Miki R,Hattori K,Taguchi Y,Tada M,Isosaka T,Hidaka Y,Hirabayashi T,Hashimoto R,Fukuzako H,Yagi T, GENE, ELSEVIER SCIENCE BV, Vol. 349, p. 1-14, 2004/07
  • Myelination triggers down-regulation of axonal CNR/Protocadherinα family expression, Morishita H,Murata Y,Esumi S,Hamada S,Yagi T, Eur. J, Neurosci., 2004/06
  • Auditory-conditioned-fear-dependent c-Fos expression is altered in the emotion-related brain structures of Fyn-deficient mice, Kubota O,Hattor K,Hashimoto K,Yagi T,Sato T,Iyo M,Yuasa S, Mol. Brain Res., Vol. 130, p. 149-160, 2004/06
  • Interaction with protocadherin-gamma regulates the cell surface expression of protocadherin-alpha, Y Murata,S Hamada,H Morishita,T Mutoh,T Yagi, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 279, No. 47, p. 49508-49516, 2004/06
  • NMDA receptor GluRepsilon/NR2 subunits are essentil for postsynaptic localization and protein stability of GluRzeta 1/NR1 subunit, Abe M,Fukuya M,Yagi T,Mishina M,Watanabe M,Sakimura K, J. Neuroscei., 2004/05
  • Genomic organization and transcripts of the zebrafish Protocadherin genes, Tada T,Senzaki K,Tai Y,Morishita H,Tanaka Y,Murata Y,Ishii Y,Asakawa S,Shimizu N,Sugino H,Yagi T, Gene, ELSEVIER SCIENCE BV, Vol. 340, No. 2, p. 197-211, 2004/05
  • Defective neocortical development in Fyn-tyrosine-kinase-deficient mice, Yuasa S,Hattori K,Yagi T, Neuro Report, LIPPINCOTT WILLIAMS & WILKINS, Vol. 15, No. 5, p. 819-822, 2004/04
  • Distinct genomic sequence of the CNR/Pcdhαgenes in chiken, Sugino H,Yanase H,Hamada S,Kurokawa K,Asakawa S,Shimizu N,Yagi T, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 316, No. 2, p. 437-445, 2004/04
  • Cadherin-related Neuronal Receptor 1(CNR1) has cell-adhesion activity with β1 integrin mediated through the RGD site of CNR1, Mutoh T,Hamada S,Yagi T, EXPERIMENTAL CELL RESEARCH, ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 294, No. 2, p. 494-508, 2004/04
  • Genomic sequence and organization of the family of CNR /Pcdhα genes in Rat, Yanase H,Sugino H,Yagi T, GENOMICS, ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 83, No. 4, p. 717-726, 2004/04
  • Exposure to hexanal odor influences maternal behavior and induces neonatal death in Fyn tyrosine kinase-deficient mice, Hamaguchi-Hamada K,Sanbo C,Hamada S,Yagi T, Neurosci. Res., ELSEVIER SCI IRELAND LTD, Vol. 48, No. 3, p. 259-267, 2004/03
  • Intron-less processed cadherin-related neuronal receptor (CNR/Pcdha) genes in the central nervous system, Sugino H,Miyazaki M,Yagi T, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 313, No. 3, p. 775-783, 2004/01
  • Role of Fyn tyrosine kinase in ethanol consumption by mice., Cowen MS,Schumann G,Yagi T,Spanagel R, Alcohol Clin Exp Res., 2003/08
  • Signaling via Immunoglobulin Fc Receptors Induces Oligodendrocyte Precursor Cell Differentiation, Nakahara J,Tan-Takeuchi K,Seiwa C,Gotoh M,Kaifu T,Ujike A,Inui M,Yagi T,Ogawa M,Aiso S,Takai T,Asou H, Developmental Cell, Vol. 4, No. 6, p. 841-52, 2003/06
  • Mouse circadian rhythm before the Kobe earthquake in 1995., Yokoi S,Ikeya M,Yagi T,Nagai K, Bioelectromagnetics, WILEY-LISS, Vol. 24, No. 4, p. 289-291, 2003/03
  • Cadherin-related Neuronal Receptors in Incisor Development, Fukumoto E,Sakai H,Fukumoto S,Yagi T,Takagi O,Kato Y, J Dent Res., Vol. 82, No. 1, p. 17-22, 2003/02
  • Distorted Odor Maps in the Olfactory Bulb of Semaphorin 3A-Deficient Mice, Taniguchi M,Nagao H,Takahashi Y,Yamaguchi M,Mitsui S,Yagi T,Mori K,Shimizu T, The Journal of Neuroscience, Vol. 23, p. 1390-1397, 2003/02
  • Differential non-target-derived repulsive signals play a critical role in shaping initial axonal growth of dorsal root ganglion neurons., Masuda T,Tsuji H,Taniguchi M,Yagi T,Tessier-Lavigne M,Fujisawa H,Okado N,Shiga T, Developmental Biology, Vol. 254, p. 289-302, 2003/02
  • 神経系における多様化膜分子群：遺伝子クラスターを形成するCNR/プロトカドヘリンファミリー, 濱田俊,八木健, 比較生理生化学, 2003/01
  • Diversity of the cadherin-related neuronal receptor/protocadherin family and possible DNA rearrangement in the brain, T Yagi, GENES TO CELLS, BLACKWELL PUBLISHING LTD, Vol. 8, No. 1, p. 1-8, 2003/01
  • Structural studies of the carbon monoxide complex of [NiFe]hydrogenase from Desulfovibrio vulgaris Miyazaki F: Suggestion for the initial activation site for dihydrogen, H Ogata,Y Mizoguchi,N Mizuno,K Miki,S Adachi,N Yasuoka,T Yagi,O Yamauchi,S Hirota,Y Higuchi, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, AMER CHEMICAL SOC, Vol. 124, No. 39, p. 11628-11635, 2002/10
  • Fyn is essential for tyrosinase phosphorylation of Csk-binding protein/phosphoprotein associated with glycolipid-enriched microdomains in lipid rafts in resting T cells., Yasuda K,Nagafuku M,Shima T,Okada M,Yagi T,Yamada T,Minaki Y,Kato A,Tani-ichi S,Hamaoka T,Kosugi A, J Immunol,169,2813-2817, AMER ASSOC IMMUNOLOGISTS, Vol. 169, No. 6, p. 2813-2817, 2002/10
  • Fyn and Cdk5 Mediate Semaphorin-3A Signaling, Which is Involved in Regulation of Dendrite Orientation in Cerebral Cortex, Sasaki Y,Cheng C,Uchida Y,Nakajima O,Ohshima T,Yagi T,Taniguchi M,Nakayama T,Kishida R,Kudo Y,Ohno S,Nakamura F,Goshima Y, 2002/08
  • Fyn Tyrosinase in Sertoki Cells Is Involved in Mouse Spermatogenesis, Maekawa M,Toyama Y,Yasda M,Yagi T,Yuasa S, Biol. Reprod., Vol. 66, p. 211-221, 2002/08
  • Wengen, a member of the Drosophila TNF receptor superfamily, is required for Eiger signaling, Kanda H,Igaki T,Kanuka H,Yagi T,Miura M, J. Biol. Chem., Vol. 277, p. 28372-28375, 2002/08
  • 脳機能形成メカニズムに関与する多様化した接着分子群-シナプスに存在する接着分子の多様性と分子間相互作用について, 武藤哲司,八木健, 脳の科学, 2002/07
  • 脳機能形成メカニズムに関与する多様化した接着分子郡-シナプスに存在する接着分子の多様性と分子間相互作用について-, 武藤哲司,八木 健, 脳の科学 24:747-754, ㈱聖和書店, 2002/06
  • 生命の知恵 多様性をもたらす無駄, 八木 健, 科学 Vol.72 No.3 Mar. 2002 323-329, 岩波書店, 2002/06
  • Requirement of neuropilin 1-mediated Sema3A signals in patterning of the sympathetic nervous system., Kawasaki T,Bekku Y,Suto F,Kitsukawa T,Taniguchi M,Nagats I,Nagatsu T,Itoh K,Yagi T,Fujisawa H, Development, Vol. 129, p. 671-680, 2002/02
  • Light-potentiation of acoustic startle response (ASR) and monoamine efflux related to fearfulness in Fyn-deficient mice., Hironaka N,Yagi T,Niki H, 2002/01
  • Adult murine neurons: their chromatine and chromosome changes and failure to support embryonic development as revealed by nuclear transfer, Osada T,Kusakabe H,Akutsu H,Yagi T,Yanagimachi R, Cytogenetic and Genome Research, S. Karger AG, Vol. 97, No. 1-2, p. 7-12, 2002/01
  • Diversity of the cadherin-related neuronal receptor family in the nervous system, Yagi T,Tada M,Tanaka Y,Senzaki K,Hirayama T,Hamada S,Sugino H, International Congress Series, Vol. 1246, p. 127-136, 2002
  • Interaction of the SH2 domain of Fyn with a cytoskeletal protein, β-aducin., Shima T,Okumura N,Takao T,Satomi Y,Yagi T,Okada M,Nagai K, Journal of Biological Chemistry, Vol. 276, No. 45, p. 42233-42240, 2001/11
  • Guidance of glial precursor cell migration by secreted cues in the developing optic nerve., Sugimoto Y,Taniguchi M,Yagi T,Akagi Y,Nojyo Y,Tamamaki N, 2001/09
  • Differential effect of Fyn tyrosine kinase deletion on offensive and defensive aggression., Miyakawa T,Yagi T,Takao K,Niki H, Behavioural brain research, 1, Vol. 122, p. 51-56, 2001/07
  • 脳の獲得的性質を支える分子メカニズムの探索 CNR／プロトカドヘリンファミリーの遺伝子構造と機能, 平山晃斉,杉野英彦,八木 健, 蛋白質 核酸 酵素 Vol.46 No.6(2001) 698-705, 2001/06
  • 脳機能形成メカニズムにかかわる多様化膜分子群, 八木 健, ポストシーケンスのゲノム科学④ ゲノムから固体へ 生命システムの理解に向けて 148－163, 中山書店, 2001/06
  • N-Methyl-d-aspartate-induced c-Fos expression is enhanced in the forebrain structures related to emotion in Fyn-deficient mice., Hattori K,Yagi T,Maekawa M,Sato T,Yuasa S, Brain Res., Vol. 905, p. 188-198, 2001/06
  • Transgenic and gene "knockout" models in alcohol research., Hoffmn PL,Yagi T,Tabakoff B,Phillips TJ,Kono H,Messing RO,Choi D-S, 2001/05
  • Two novel CNRs from the CNR gene cluster have molecular features distinct from those of CNR1 to 8., Takei Y,Hamada S,Senzaki K,Mutoh T,Sugino H,Yagi T, GENOMICS, ACADEMIC PRESS INC, Vol. 72, No. 3, p. 321-330, 2001/03
  • Myelin basic protein is necessary for the regulation of myelin-associated glycoprotein expression in mouse oligodendroglia., Nakahara J,Tan-Takeuchi K,Seiwa C,Yagi T,Aiso S,Kawamura K,Asou H, 2001/02
  • Somatic mutations of synaptic cadherin (CNR family) transcripts in the nervous system., Hirayama T,Sugino H,Yagi T, Genes Cells, Vol. 6, p. 151-164, 2001/02
  • Enhancement of hippocampal LTP, reference memory and sensorimotor gating in mutant mice lacking a telencephalon-specific cell adhesion molecule., Nakamura K,Manabe T,Watanabe M,Mamiya T,Ichikawa R,Kiyama Y,Sanbo M,Yagi T,Inoue Y,Nabeshima T,Mori H,Mishina M, 2001/01
  • Signaling cascade of CNR cadherins (Reelin receptors) in the mammalian brain, Yagi.T, 2001/01
  • Mouse embryonic stem (ES) cell lines established from neuronal cell-derived cloned blastocysts., Kawase E,Yamazaki Y,Yagi T,Yanagimachi R,Pedersen R.A, Genesis, Vol. 28, p. 156-163, 2000/11
  • シナプス形成とカドヘリンスーパーファミリー－シナプス形成の分子基盤か？-, 濱田俊,八木健, 脳２１, 2000/10
  • Involvement of complexin II in synaptic plasticity in the CA1 region of the hippocampus: the use of complexin II-lacking mice., Huang G-Z,Ujihara H,Takahashi S,Kaba H,Yagi T,Inoue S, The Japanese Journal of Pharmacology, The Japanese Pharmacological Society, Vol. 84, No. 2, p. 179-187, 2000/10
  • Repulsive axon guidance molecule Sema3A inhibits branching morphogenesis of fetal mouse lung., Ito T,Kagoshima M,Sasaki Y,Li C,Udaka N,Kitukawa T,Fujisawa H,Taniguchi M,Yagi T,Kitamura H,Goshima Y, 2000/10
  • The presence of a SO molecule in [NiFe] hydrogenase from Desulfovibrio vulgaris Miyazaki as detected by mass spectrometry, Y Higuchi,F Toujou,K Tsukamoto,T Yagi, JOURNAL OF INORGANIC BIOCHEMISTRY, ELSEVIER SCIENCE INC, Vol. 80, No. 3-4, p. 205-211, 2000/07
  • マウス大脳皮質層構造形成機構における新たな分子メカニズムの解明－CNRファミリーはReelinの多重受容体である－, 先崎浩次,小川正晴,八木 健, 実験医学 Vol.18 No.6(4月号）2000, 2000/06
  • Cadherin superfamily genes: functions, genomic organization, and neurologic diversity., Yagi T,Takeichi M, Genes Dev, Vol. 14, p. 1169-1180, 2000/05
  • Fyn tyrosine kinase participates in the compact myelin sheath formation in the central nervous system., Seiwa C,Sugiyama I,Yagi T,Iguchi T,Asou H, Vol. 37, No. 1, p. 21-31, 2000/03
  • In vivo gene transfer to mouse spermatogenic cells using green fluorescent protein as a marker., Yamazaki Y,Yagi T,Ozaki T,Imoto K, J. Exp. Zool., Vol. 286, p. 212-218, 2000/02
  • Dynamic characteristics and adaptability of reflex eye movements of Fyn kinase-deficient mice., Kitazawa H,Katoh A,Yagi T,Nagao S, 2000/02
  • Impairment of conditioned avoidance response in Fyn-kinase deficient mice., Zhen-tong M,Xiao-feng M,Yagi T,Yamagishi S, 2000/01
  • Proteins of the CNR family are multiple receptors for Reelin., Senzaki K,Ogawa M,Yagi T, Cell, Vol. 99, p. 635-647, 1999/12
  • A requirement for neuropilin-1 in embryonic vessel formation., Kawasaki T,Kitsukawa T,Bekku Y,Matsuda Y,Sanbo M,Yagi T,Fujisawa H, Development, Vol. 126, p. 4895-4902, 1999/12
  • Reduced hippocampal LTP in mice lacking a presynaptic protein: complexin II., Takahashi S,Ujihara H,Huang G-Z,Yagyu K,Sanbo M,Kaba H,Yagi T, Eur J Neurosci, Vol. 11, p. 2539-2366, 1999/07
  • 免疫系多様化分子郡と類似性を示す中枢神経系の新規カドヘリン（CNR)ファミリー, 八木 健, 脳の科学，21：923-936，1999, ㈱聖和書店, 1999/06
  • Enrichment and efficient screening of ES cells containing a targeted mutation: the use of DT-A gene with the polyadenylation signal as a negative selection maker., Yanagawa Y,Kobayashi T,Ohnishi M,Kobayashi T,Tamura S,Tsuzuki T,Sanbo M,Yagi T,Tashiro F,Miyazaki J, Transgenic Res., Vol. 8, p. 215-221, 1999/06
  • Removal of the bridging ligand atom at the Ni-Fe active site of [NiFe] hydrogenase upon reduction with H-2, as revealed by X-ray structure analysis at 1.4 angstrom resolution, Y Higuchi,H Ogata,K Miki,N Yasuoka,T Yagi, STRUCTURE WITH FOLDING & DESIGN, CURRENT BIOLOGY LTD, Vol. 7, No. 5, p. 549-556, 1999/05
  • Molecular mechanisms of Fyn-tyrosine kinase for regulating mammalian behaviors and an ethanol sensitivity., Yagi T, Biochem. Pharmacol., Vol. 57, p. 845-850, 1999/04
  • Liberation of hydrogen sulfide during the catalytic action of Desulfovibrio hydrogenase under the atmosphere of hydrogen, Y Higuchi,T Yagi, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC, Vol. 255, No. 2, p. 295-299, 1999/02
  • テレンセファリン遺伝子にCreリコンビナーゼ遺伝子を挿入した変異マウスの作製と解析, 中村 和裕,森 寿,城山 優治,八木 健,真鍋 俊也,高橋 智幸,渡辺 雅彦,市川 量一,井上 芳郎,三品 昌美, 神経化学, (一社)日本神経化学会, Vol. 37, No. 3, p. 555-555, 1998/09
  • Role of the carboxy-terminal region of the GluRε2 subunit in synaptic localization of the NMDA receptor channel., Mori H,Manabe T,Watanabe M,Satoh Y,Suzuki N,Toki S,Nakamura K,Yagi T,Kushiya E,Takahashi T,Inoue Y,Sakimura K,Mishina M, 1998/09
  • 脳の機能と遺伝情報, 八木 健, 脳の科学，20：555-558，1998, ㈱聖和書店, 1998/06
  • Efficient production of Cre-mediated site-directed Efficient production of Cre-mediated site-directed recombinants through the utilization of the puromycin resistance gene, pac: a transient gene-integration marker for ES cells., Taniguchi M,Sanbo M,Watanabe S,Naruse I,Mishina M,Yagi T, 1998/01
  • Diversity revealed by a novel family of cadherins expressed in neurons at a synaptic complex., Kohmura N,Senzaki K,Hamada S,Kai N,Yasuda R,Watanabe M,Ishii H,Yasuda M,Mishina M,Yagi T, Neuron, Cell Press, Vol. 20, p. 1137-1151, 1998/01
  • Abnormal synaptic transmission in the olfactory bulb of Fyn-kinase deficient mice., Kitazawa H,Yagi T,Miyakawa T,Niki H,Kawai N, Journal of neurophysiology, 1, Vol. 79, p. 137-142, 1998/01
  • Unusual ligand structure in Ni-Fe active center and an additional Mg site in hydrogenase revealed by high resolution X-ray structure analysis, Y Higuchi,T Yagi,N Yasuoka, STRUCTURE, CELL PRESS, Vol. 5, No. 12, p. 1671-1680, 1997/12
  • Neuropilin-Semaphorin III/D-Mediated Chemonepulsive Signals play a crucial Role in Peripheral Nerve Projection in Mice., Kitsukawa T,Shimizu M,Sanbo M,Hirata T,Taniguchi M,Bekku Y,Yagi T,Fujisawa H, Neuron, Vol. 19, p. 995-1005, 1997/11
  • Fyn-kinase as a determinant of ethanol sensitivity: Relation to NMDA-receptor function., Miyakawa T,Yagi T,Kitazawa H,Yasuda M,Kawai N,Tsuboi K,Niki H, Science (New York, N.Y.), 5338, Vol. 278, No. 5338, p. 698-701, 1997/10
  • Disruption of semaphorin III/D gene causes severe abnormality in peripheral nerve projection., Taniguchi M,Yuasa S,Fujisawa H,Naruse I,Saga S,Mishina M,Yagi T, Neuron, Vol. 19, p. 519-519, 1997/09
  • Suppression of autoimmune disease and of massive lymphadenopathy in MR/MRL-lpr/lpr mice lacking tyrosine kinase Fyn (p59fyn)1., Takahashi T,Yagi T,Kakinuma S,Kurokawa A,Okada T,Takatsu K,Aizawa S,Katagiri T, J. Immunol., Vol. 159, p. 2532-2532, 1997/09
  • 脳の進化をもたらした遺伝子の探索―情動形成に関わる分子メカニズムによる研究―, 八木 健, 細胞工学 Vol.16 No.8 1140-1149, 秀潤社, 1997/06
  • Fyn欠損マウスの脳形成・機能異常の解析, 八木 健, 神経研究の進歩 第41巻 第5号 1997年10月, 医学書院, 1997/06
  • マウス固体における遺伝子ノックアウト, 八木 健, 日本生理学雑誌 第59巻 第10号（平成9年）, 1997/06
  • Molecular cloning of Fyn-associated molecules in the mouce central nervous system., Kai N,Mishina M,Yagi T, 1997/06
  • Cleft palate and decreased brain γ-aminobutyric acid in mice lacking the 67-kDa isoform of glutamic acid decarboxylase., Asada H,Kawamura Y,Maruyama K,Kume H,Ding R-D,Kanbara N,Kuzume H,Sanbo M,Yagi T,Obata K, Proc Natl Acad Sci USA, Vol. 94, p. 6496-6499, 1997/06
  • Mice lacking the 65 kDa isoform of glutamic acid decarboxylase (GAD65) maintain normal levels of GAD67 and GABA in their brain but are susceptible to seizures., Asada H,Kawamura Y,Maruyama K,Kume H,Ding R-G,Ji F-U,Kanbara N,Kuzume H,Sanbo M,Yagi T,Obata K, Biochem Biophys Res Commun, Vol. 229, p. 891-895, 1996/12
  • Impairment of suckling response, trigeminal neuronal pattern formation and hippocampal LTD in NMDA receptor ε2 subunit mutant mice., Kutsuwada T,Sakimura K,Manabe T,Takayama C,Katakura N,Kushiya E,Natsume R,Watanabe M,Inoue Y,Yagi T,Aizawa S,Arakawa M,Takahashi T,Nakamura Y,Mori H,Mishina M, Neuron, Vol. 16, p. 333-344, 1996/12
  • Susceptibility to drug-induced seizures of Fyn tyrosine kinase-deficient mice., Miyakawa T,Yagi T,Tateishi K,Niki H, Neuroreport, 15-17, Vol. 7, p. 2723-2726, 1996/12
  • Radial maze performance, open-field and elevated plus-maze behaviors in Fyn-kinase deficient mice: further evidence for increased fearfulness., Miyakawa T,Yagi T,Kagiyama A,Niki H, Brain research. Molecular brain research, 1-2, Vol. 37, No. 1/2, p. 145-150, 1996/04
  • Physical and functional association of the cbl proto-oncogene product with an src-family protein tyrosine kinase, p53/56lyn, in the B cell antigen receptor-mediated signaling., Tezuka T,Umemori H,Fusaki N,Yagi T,Takata M,Kurosaki T,Yamamoto T, J Exp Med., Vol. 183, p. 675-680, 1996/02
  • Involvement of Fyn tyrosine kinase in progression of cytokinesis of B lymphocyte progenitor., Yasunaga M,Yagi T,Hanzawa N,Yasuda M,Yamanashi Y,Yamamoto T,Aizawa S,Miyauchi Y,Nishikawa S, 1996/01
  • Experimental analysis of behavior of Fyn-tyrosine kinase-deficient mice, H Niki,T Miyakawa,T Yagi, BRAIN PROCESSES AND MEMORY, ELSEVIER SCIENCE PUBL B V, Vol. 1108, p. 279-290, 1996
  • Molecular cloning of a novel serine/threonine kinase, MRK, possibly involved in cardiac development, Abe S,Yagi T,Ishiyama S,Hiroe M,Marumo F,Ikawa Y, 1995/12
  • Reduced spontaneous activity of mice defective in the e4 subunit of the NMDA receptor channel., Ikeda K,Araki K,Takayama C,Inoue Y,Yagi T,Aizawa S,Mishina M, 1995/10
  • Stable production of mutant mice from double gene converted ES cells with puromycin and neomycin, Watanabe S,Kai N,Yasuda M,Kohmura N,Sanbo M,Mishina M,Yagi T, Biochem. Biophys. Res. Commun., Vol. 213, p. 130-137, 1995/08
  • A new strategy of gene trapping in ES cells using 3' RACE., Yoshida M,Yagi T,Furuta Y,Takayanagi K,Kominami R,Takeda N,Tokunaga T,Chiba J,Ikawa Y,Aizawa S, Transgenic Res, Vol. 4, p. 277-287, 1995/07
  • 特集 遺伝子ターゲティング 特集によせて, 八木 健, 組織培養 21（２），35－37，1995, 1995/06
  • Impairment of motor coordination, Purkinje cell synapse formation, and cerebellar long-term depression in GluR delta2 mutant mice., Kashiwabuchi N,Ikeda K,Araki K,Hirano T,Shibuki K,Takayama C,Inoue Y,Kutsuwada T,Yagi T,Kang Y,Aizawa S,Mishina M, Cell, Vol. 81, p. 245-252, 1995/04
  • Enhanced susceptibility of audiogenic seizures in Fyn-kinase deficient mice., Miyakawa T,Yagi T,Taniguchi M,Matsuura H,Tateishi K,Niki H, Brain research. Molecular brain research, 2, Vol. 28, No. 2, p. 349-352, 1995/02
  • Behaviral Abnormalities of Gene Targetted Mice., YAGI Takeshi, Proceedings of The Japanese Society of Animal Models for Human Diseases, Japanese Association for Laboratory Animal Science, Vol. 11, p. 29-31, 1995
  • Reduced hippocampal LTP and spatial learning in mice lacking NMDA receptor epsilon 1 subunit., Sakimura K,Kutsuwada T,Ito I,Manabe T,Takayama C,Kushiya E,Yagi T,Aizawa S,Inoue Y,Sugiyama H,Mishina M, Nature, Vol. 373, p. 151-155, 1995/01
  • Gene targeting of fyn tyrosine kinase in murine nervous system. Genes for development, cell growth and infectious diseases,, Yagi T, 1995/01
  • Increased fearfulness of Fyn tyrosine kinase deficient mice., Miyakawa T,Yagi T,Watanabe S,Niki H, Brain research. Molecular brain research, 1, Vol. 27, No. 1, p. 179-182, 1994/12
  • Insulin resistance and growth retardation in mikce lacking insulin receptor substrate-1, Tamemoto H,Kadowaki T,Tobe K,Yagi T,Sakura H,Hayakawa T,Terauchi Y,Ueki K,Kaburagi Y,Satoh S,Sekihara H,Yoshioka S,Horikoshi H,Furuta Y,Ikawa Y,Kasuga M,Yazaki Y,Aizawa S, Nature, Vol. 372, No. 6502, p. 182-6, 1994/11
  • A novel nonreceptor tyrosine kinase, Srm; cloning and targeted disruption, Kohmura N,Yagi T,Tomooka Y,Oyanagi M,Kominami R,Takeda N,Chiba J,Ikawa Y,Aizawa S, 1994/10
  • Fyn expression during neurogenesis in mouse embryo., Yagi T,Shigetani Y,Furuta Y,Nada S,Okado N,Ikawa Y,Aizawa S, Oncogene, Vol. 9, No. 9, p. 2433-2440, 1994/09
  • Src family kinases control neural development and function, Yagi T, Develop Growth Differ, Vol. 36, p. 543-550, 1994/06
  • Initial events of myelination involve Fyn tyrosine kinase signalling., Umemori H,Sato S,Yagi T,Aizawa S,Yamamoto T, Nature, Vol. 367, p. 572-576, 1994/02
  • HEXADECAHEME CYTOCHROME-C, Y HIGUCHI,T YAGI,G VOORDOUW, INORGANIC MICROBIAL SULFUR METABOLISM, ACADEMIC PRESS INC, Vol. 243, p. 155-165, 1994
  • Non-receptor tyrosine kinases in mammalian neurogenesis., Aizawa S,Yagi T,Furuta Y,Ikawa Y, Princess Takamatsu symposia, Vol. 24, p. 323-337, 1994/01
  • A role for Fyn tyrosine kinase in the suckling behaviour of neonatal mice., Yagi T,Aizawa S,Tokunaga T,Shigetani Y,Takeda N,Ikawa Y, Nature, Vol. 366, p. 742-745, 1993/12
  • Regional localization of Fyn in adult brain; studies with mice in which fyn gene was replaced by lacZ, Yagi T,Shigetani Y,Okado N,Tokunaga T,Ikawa Y,Aizawa S, Oncogene, Vol. 8, p. 3343-3343, 1993/12
  • Enhanced proliferative potential in culture of cells from p53-deficient mice, Tsukada T,Tomooka Y,Takai S,Ueda Y,Nishikawa S,Yagi T,Tokunaga T,Takeda N,Suda Y,Abe S,Masuo I,Ikawa Y,Aizawa S, Oncogene, Vol. 8, p. 3313-3322, 1993/12
  • A novel negative selection for homologous recombinants using diphtheria toxin A fragment gene, Yagi T,Nada S,Watanabe N,Tamemoto H,Kohmura N,Ikawa Y,Aizawa S, Analytical Biochemistry, Vol. 214, No. 1, p. 77-86, 1993/10
  • A novel ES cell line, TT2, with high germline-differentiating potency, Yagi T,Tokunaga T,Furuta Y,Nada S,Yoshida M,Tsukada T,Saga Y,Takeda N,Ikawa Y,Aizawa S, Analytical Biochemistry, Vol. 214, No. 1, p. 70-76, 1993/10
  • マウス遺伝子ターゲティングの実際, 塚田 晃代,八木 健, 実験医学 Vol.11 No.2(2月号）１９９３、実験医学 Vol.12 No.2(増刊号）１９９４, ㈱羊土社, 1993/06
  • Constitutive Activation of Src family kinase in mouse embryos that lack CskS., Nada S,Yagi T,Takeda H,Tokunaga T,Nakagawa H,Ikawa Y,Okada M,Aizawa S, Cell, Vol. 73, No. 6, p. 1125-1135, 1993/06
  • A novel tyrosine kinase, hyk, expressed in murine embryonic stem cells., Horita K,Yagi T,Kohmura N,Tomooka Y,Ikawa Y,Aizawa S, 1992/12
  • Mice develop normally without tenascin, Saga Y,Yagi T,Ikawa Y,Sakakura T,Aizawa S, Genes Dev, Vol. 6, p. 1821-1831, 1992/10
  • A new method for negatively selecting random integrants using diphteria toxin A fragment gene: Efficacious isolation of homologous recombinants at c-fyn locus of mouse embryonic stem cells, Yagi T,Imamura T,Suda Y,Ikawa Y,Tokunaga T,Aizawa S, 1992/01
  • Homologous recombination in ES cells, ㈱メディカルレビュー社, 1991/12
  • ジフテリア毒素Aフラグメント遺伝子をネガティブ選別に用いる相同組換え細胞選別法, 八木 健, 細胞工学「Vol.10 No.6 408-415, 秀潤社, 1991/06
  • Homologous recombination at c-fyn locus of mouse embryonic stem cells with use of diphtheria toxin A-fragment gene in negative selection, Yagi T,Ikawa Y,Yoshida K,Shigetani Y,Takeda N,Mabuchi I,Yamamoto T,Aizawa S, Proc Natl Acad Sci U S A, Vol. 87, p. 9918-9922, 1990/12
  • Env-derived gp55 gene of Friend spleen focus-forming virus specifically induces neoplastic proliferation of erythroid progenitor cells, Aizawa S,Suda Y,Furuta Y,Yagi T,Takeda N,Watanabe N,Nagayoshi M,Ikawa Y, EMBO J., Vol. 9, p. 2107-2116, 1990/07
  • ES細胞を用いる変異マウスの作製―相同的組換えによる変異の導入, 八木 健,相沢 慎一, 代謝VOL.27 増刊号「免疫'90」177-186, 中山書店, 1990/06
  • Induction of a variety of tumors by c-erbB2 and clonal nature of lymphomas even with the mutated gene (Val659 to Glu659), Suda Y,Aizawa S,Furuta Y,Yagi T,Ikawa Y,Saitoh K,Yamada Y,Toyoshima K,Yamamoto T, EMBO J., Vol. 9, p. 181-190, 1990/06
  • SINGLE-CRYSTALS OF HYDROGENASE FROM DESULFOVIBRIO-VULGARIS MIYAZAKI-F, Y HIGUCHI,N YASUOKA,M KAKUDO,Y KATSUBE,T YAGI,H INOKUCHI, JOURNAL OF BIOLOGICAL CHEMISTRY, AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, Vol. 262, No. 6, p. 2823-2825, 1987/02
  • CRYSTALLOGRAPHIC STUDY OF CYTOCHROME-C553 FROM DESULFOVIBRIO-VULGARIS MIYAZAKI, A NAKAGAWA,E NAGASHIMA,Y HIGUCHI,M KUSUNOKI,Y MATSUURA,N YASUOKA,Y KATSUBE,H CHIHARA,T YAGI, JOURNAL OF BIOCHEMISTRY, JAPANESE BIOCHEMICAL SOC, Vol. 99, No. 2, p. 605-606, 1986/02
  • THE STRUCTURE OF CYTOCHROME-C3 FROM DESULFOVIBRIO-VULGARIS MIYAZAKI AT 2.5-A RESOLUTION, Y HIGUCHI,S BANDO,M KUSUNOKI,Y MATSUURA,N YASUOKA,M KAKUDO,T YAMANAKA,T YAGI,H INOKUCHI, JOURNAL OF BIOCHEMISTRY, JAPANESE BIOCHEMICAL SOC, Vol. 89, No. 5, p. 1659-1662, 1981
  • ON CYTOCHROME-C3 FOLDING, Y HIGUCHI,M KUSUNOKI,N YASUOKA,M KAKUDO,T YAGI, JOURNAL OF BIOCHEMISTRY, JAPANESE BIOCHEMICAL SOC, Vol. 90, No. 6, p. 1715-1723, 1981

Misc.

  • 大脳皮質神経細胞群の多様な個性の獲得におけるDNAメチル化の関与, 宮下俊雄,宮下俊雄,三宝誠,平林真澄,八木健,吉村由美子, 日本解剖学会総会・全国学術集会講演プログラム・抄録集, Vol. 123rd, 2018
  • 変異蓄積モデルを利用した生殖系列変異の後世代影響の解析, 内村有邦,内村有邦,樋口真弓,八木健, 放射線生物研究, Vol. 52, No. 4, 2017
  • Gene codes for generating neural circuits of individual neurons : clustered protocadherins, Vol. 68, No. 1, p. 48-53, 2017/01
  • プロトカドヘリンγは大脳皮質抑制性神経細胞の分布及び機能を制御する, 有賀理瑛,平山晃斉,吉武講平,足澤悦子,吉村由美子,澁木克栄,八木健, 日本生物学的精神医学会(Web), Vol. 38th, 2016
  • Estimation of germline mutation rate by using mutation accumulation mouse lines, Arikuni Uchimura,Mayumi Higuchi,Eri Niimi,Yohei Minakuchi,Atsushi Toyoda,Asao Fujiyama,Jo Nishino,Takeshi Yagi, GENES & GENETIC SYSTEMS, GENETICS SOC JAPAN, Vol. 90, No. 6, p. 368-368, 2015/12
  • CTCF欠失は大脳皮質抑制性神経細胞の分布と神経活動に影響を及ぼす, 有賀理瑛,谷垣宏美,平山晃斉,吉武講平,足澤悦子,CALJART Niels,吉村由美子,渋木克栄,八木健, 日本生化学会大会(Web), Vol. 88th, 2015
  • 生後発達過程の大脳皮質においてPolβ欠損神経細胞は2本鎖DNA切断を異常に蓄積させる, 植田尭子,大西公平,菅生紀之,菅生紀之,豊田峻輔,豊田峻輔,平山晃斉,平山晃斉,八木健,八木健,山本亘彦, 日本生化学会大会(Web), Vol. 88th, 2015
  • The estimation of per generation mutation rate and its effects by using long-term breeding mouse lines, Arikuni Uchimura,Mayumi Higuchi,Yohei Minakuchi,Jo Nishino,Atushi Toyoda,Asao Fujiyama,Ikuo Miura,Shigaharu Wakana,Yagi Takeshi, GENES & GENETIC SYSTEMS, GENETICS SOC JAPAN, Vol. 89, No. 6, p. 285-285, 2014/12
  • Higher germline mutation rate affects mouse phenotypes after long-term breeding, Arikuni Uchimura,Mayumi Higuchi,Atsushi Toyoda,Asao Fujiyama,Ikuo Miura,Shigeharu Wakana,Takeshi Yagi, GENES & GENETIC SYSTEMS, GENETICS SOC JAPAN, Vol. 88, No. 6, p. 354-354, 2013/12
  • 多様化したカドヘリン様膜分子群クラスター型プロトカドヘリンの生理機能, 平林 敬浩,八木 健, 生体の科学, Vol. 64, p. 450-451, 2013
  • Analysis of mouse mutant exhibiting a rare human-audible vocalization behavior, Takeshi Yagi,Arikuni Uchimura,Yukinori Inoue,Mayumi Higuchi,Yuko Hidaka,Nao Wakui,Yoshichika Yoshioka,Seiji Ishikawa,Ichiro Tateya,Ryoko Nakagawa,Kazuo Okanoya,Ikuo Miura,Shigeharu Wakana, GENES & GENETIC SYSTEMS, GENETICS SOC JAPAN, Vol. 87, No. 6, p. 389-389, 2012/12
  • The phenotypic effects of accumulated germline mutations in long-term mutator mouse breeding, Arikuni Uchimura,Mayumi Higuchi,Yuko Hidaka,Atsushi Toyoda,Asao Fujiyama,Ikuo Miura,Shigeharu Wakana,Takeshi Yagi, GENES & GENETIC SYSTEMS, GENETICS SOC JAPAN, Vol. 87, No. 6, p. 382-382, 2012/12
  • Single-neuron diversity generated by Protocadherin-β cluster in mouse central and peripheral nervous systems, Keizo Hirano,Ryosuke Kaneko,Takeshi Izawa,Masahumi Kawaguchi,Takashi Kitsukawa,Takeshi Yagi, Frontiers in Molecular Neuroscience, Frontiers Media SA, Vol. 5, 2012
  • Effects Caused by Higher Germline Mutation Rate into Mammalian System, Arikuni Uchimura,Yuko Hidaka,Ikuo Miura,Shigeharu Wakana,Takeshi Yagi, GENES & GENETIC SYSTEMS, GENETICS SOC JAPAN, Vol. 86, No. 6, p. 398-398, 2011/12
  • Combinatorial neural receptor matching network, a hypothetical brain micro-circuit inspired by combinatorial expression of diversified adhesion molecules, Takashi Kitsukawa,Takeshi Yagi, NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, Vol. 71, p. E77-E77, 2011
  • Differential regulation between duplicated genes in protocadherin-alpha cluster acquired without subsequent mutations, Ryosuke Kaneko,Manabu Abe,Takahiro Hirabayashi,Arikuni Uchimura,Kenji Sakimura,Yuchio Yanagawa,Takeshi Yagi, NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, Vol. 71, p. E46-E46, 2011
  • The protocadherin-alpha family is required for normal serotonergic projections, Shota Katori,Atsushi Okayama,Evan Deneris,Takeshi Yagi, NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, Vol. 71, p. E135-E135, 2011
  • Loss of function analysis in mice for all protocadherin clusters, Takeshi Yagi,Atsushi Okayama,Yukinori Inoue,Shunsuke Toyoda,Teruyoshi Hirayama,Takahiro Hirabayashi, NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, Vol. 71, p. E95-E95, 2011
  • Analysis of Effects Caused by Higher Spontaneous Mutation Rate into Mammalian System, Arikuni Uchimura,Yuko Hidaka,Ikuo Miura,Shigeharu Wakana,Takeshi Yagi, GENES & GENETIC SYSTEMS, GENETICS SOC JAPAN, Vol. 85, No. 6, p. 437-437, 2010/12
  • クラスター型プロトカドヘリンにおける選択的組み合わせ発現の制御機構の解析, 横田慎一,平山晃斉,平林敬浩,河村佳見,金子涼輔,八木健, 生化学, (公社)日本生化学会, Vol. 83回・33回, p. ROMBUNNO.2T8-8-8, 2010/12
  • Crossing nerve transfer in the brachial plexus produces bilateral somatosensory cortical representation in mice, Haruyoshi Yamashita,Shanlin Chin,Seiji Komagata,Ryuichi Hishida,Takuji Iwasato,Shigeyoshi Itohara,Takeshi Yagi,Naoto Endo,Minoru Shibata,Katsuei Shibuki, NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, Vol. 68, p. E156-E157, 2010
  • Relationship between DNA methylation and gene expression in the protocadherin gene cluster, Shunsuke Toyoda,Masahumi Kawaguchi,Tomoko Toyama,Masaki Okano,Masaaki Oda,Takeshi Yagi, NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, Vol. 68, p. E352-E352, 2010
  • Gene duplication alters expression and DNA methylation in Protocadherin-alpha cluster, Ryosuke Kaneko,Manabu Abe,Takahiro Hirabayashi,Arikuni Uchimura,Kenji Sakimura,Yuchio Yanagawa,Takeshi Yagi, NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, Vol. 68, p. E352-E353, 2010
  • Conditional loss of gamma-Protocadherin disrupts cellular morphogenesis and regulates cell survival in the cortex, Yasuto Itoga,Kayoko Makino,Takahiro Hirabayashi,Takeshi Yagi, NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, Vol. 68, p. E145-E145, 2010
  • The Role of Protocadherin 9 in Cortical Cytoarchitecture, Asuka Matsui,Ryosuke Kaneko,Takeshi Yagi,Nobuhiko Yamamoto, NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, Vol. 68, p. E144-E144, 2010
  • Properties of higher visual cortices visualized based on the differential stimulus selectivity in mice, Manavu Tohmi,Reiko Meguro,Kentaro Nagami,Ryuichi Hishida,Masao Norita,Takeshi Yagi,Katsuei Shibuki, NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, Vol. 65, p. S204-S204, 2009
  • IMAGING OF HIGHER VISUAL CORTICES BASED ON DIFFERENCES IN RESPONSE PROPERTIES BETWEEN THE PRIMARY AND HIGHER VISUAL CORTICES IN MICE, Manavu Tohmi,Reiko Meguro,Kentaro Nagami,Ryuichi Hishida,Masao Norita,Takeshi Yagi,Katsuei Shibuki, JOURNAL OF PHYSIOLOGICAL SCIENCES, SPRINGER TOKYO, Vol. 59, p. 191-191, 2009
  • EXPERIENCE-DEPENDENT FORMATION OF CORTICAL CIRCUITS FOR DETECTING HARMONIC SOUNDS IN MICE, Hiroaki Tsukano,Yamato Kubota,Takuji Iwasato,Shigeyoshi Itohara,Takeshi Yagi,Seiji Komagata,Ryuichi Hishida,Katsuei Shibuki, JOURNAL OF PHYSIOLOGICAL SCIENCES, SPRINGER TOKYO, Vol. 59, p. 425-425, 2009
  • THE ROLE OF KINASE ACTIVITY OF Ca2+/CALMODULIN-DEPENDENT PROTEIN KINASE II IN HIPPOCAMPAL SYNAPTIC PLASTICITY AND LEARNING, Yoko Yamagata,Shizuka Kobayashi,Tatsuya Umeda,Akihiro Inoue,Hiroyuki Sakagami,Masahiro Fukaya,Masahiko Watanabe,Nobuhiko Hatanaka,Masako Totsuka,Takeshi Yagi,Kunihiko Oabata,Keiji Imoto,Yuchio Yanagawa,Toshiya Manabe,Shigeo Okabe, JOURNAL OF PHYSIOLOGICAL SCIENCES, SPRINGER TOKYO, Vol. 59, p. 182-182, 2009
  • Expression and function of protocadherin9 in the developing cortex, Asuka Matsui,Ryosuke Kaneko,Takeshi Yagi,Nobuhiko Yamamoto, NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, Vol. 65, p. S98-S99, 2009
  • Differential and monoallelic gene exprssion of Protocadherin-beta family genes in the mouse brain, Keizo Hirano,Ryosuke Kaneko,Takeshi Izawa,Takashi Kitsukawa,Takeshi Yagi, NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, Vol. 65, p. S150-S150, 2009
  • Analysis of protocadherin-alpha isoforms in serotonergic neurons, Shota Katori,Yukiko Noguchi,Takahiro Hirabayashi,Yoshimi Kawamura,Takeshi Yagi, NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, Vol. 65, p. S159-S159, 2009
  • Analysis of gamma-Protocadherin conditional targeted mice, Yasuto Itoga,Kayoko Makino,Shun Hamada,Takahiro Hirabayashi,Takeshi Yagi, NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, Vol. 65, p. S98-S98, 2009
  • The regulation of DNA methylation pattern in the Pcdh-alpha gene cluster during development, Shunsuke Toyoda,Masahumi Kawaguchi,Tomoko Toyama,Masaki Okano,Masaaki Oda,Takeshi Yagi, NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, Vol. 65, p. S151-S151, 2009
  • Roles of clustered genomic organization of Protocadherin-alpha on individual neuron specific Protocadherin-alpha choice, Ryosuke Kaneko,Manabu Abe,Takahiro Hirabayashi,Arikuni Uchimura,Kenji Sakimura,Yuchio Yanagawa,Takeshi Yagi, NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, Vol. 65, p. S89-S89, 2009
  • Generation of a novel mouse genetics model by using DNA replication error, Arikuni Uchimura,Yuko Hidaka,Mitsuru Furusawa,Takeshi Yagi, GENES & GENETIC SYSTEMS, GENETICS SOC JAPAN, Vol. 83, No. 6, p. 500-500, 2008/12
  • Activation of Fyn tyrosine kinase in the mouse dorsa hippocampus is essential for context discrimination, Tomoko Isosaka,Kotaro Hattori,Takeshi Yagi,Shigeki Yuasa, NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, Vol. 61, p. S115-S115, 2008
  • Protocadherin-alpha in the serotonergic projection, Shota Katori,Shun Hamada,Emi Fukuda,Yukiko Noguchi,Takeshi Yagi, NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, Vol. 61, p. S232-S232, 2008
  • ニューロンにおけるカドヘリンスーパーファミリーの相互作用, 平林敬浩,八木 健, 生体の科学, Vol. 58, p. 480-482, 2007/09
  • Close Up実験法 Series167 分注RT‐PCR法を用いた単一プルキンエ細胞における対立染色体での差次的遺伝子発現解析, 江角重行,江角重行,金子涼輔,八木健, 実験医学, Vol. 25, No. 9, 2007/06
  • Use of intron and exon probes to characterize the expression of immediate early genes, Takeshi Izawa,Yu Kumode,Tetsuo Yamamori,Takeshi Yagi,Takashi Kitsukawa, NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, Vol. 58, p. S111-S111, 2007
  • Fyn protein tyrosine kinase as a target for antipsychotic drugs, Kotaro Hattori,Shigeo Uchino,Tomoko Isosaka,Shinichi Kohsaka,Takeshi Yagi,Shigeki Yuasa, NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, Vol. 58, p. S49-S49, 2007
  • Protocadherin-alpha family is required for sensorimotor gating and spatial learning, Emi Fukuda,Shun Hamada,Takahiro Hirabayashi,Takeshi Yagi, NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, Vol. 58, p. S205-S205, 2007
  • Monoallelic gene repulation and combinatorial expression of Protocadherin-beta family genes confer neuronal diversity in the brain, Keizo Hirano,Ryosuke Kaneko,Takeshi Izawa,Takashi Kitsukawa,Takeshi Yagi, NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, Vol. 58, p. S141-S141, 2007
  • Protocadherin-alpha family is required for early establishment and maintenance of the olfactory axonal projection, Sonoko Hasegawa,Shun Hamada,You Kumodel,Takahiro Hirabayashi,Peter Mombaerts,Takeshi Yagi, NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, Vol. 58, p. S205-S205, 2007
  • Involvement of caspase activity in the pathfinding of olfactory sensory neurons, Shizue Ohsawa,Shun Hamada,Hiroki Yoshida,Takeshi Yagi,Masayuki Miura, NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, Vol. 58, p. S46-S46, 2007
  • Protocadherin-alpha family in the olivo-cerebellar system; their isoform expression and loss of function analysis, You Kumode,Shun Hamada,Takashi Kitsukawa,Kouichi Hashimoto,Taisuke Miyazaki,Masanobu Kano,Masahiko Watanabe,Takeshi Yagi, NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, Vol. 58, p. S206-S206, 2007
  • Localization of Protocadherin-alpha protein in the mouse hippocampal neuron, Atsushi Okayama,Ryosuke Kaneko,Takeshi Yagi, NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, Vol. 58, p. S205-S205, 2007
  • Exchange of genome structure in Protocadherin-alpha gene cluster alters their neuronal expression pattern, Yukiko Noguchi,Yoshimi Kawamura,Takahiro Hirabayashi,Arikuni Uchimura,Masahumi Kawaguchi,Shota Katori,Teruyashi Hirayama,Takeshi Yagi, NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, Vol. 58, p. S142-S142, 2007
  • Cytoplasmic domain of Protocadherin-alpha is essential for establishment of normal serotonergic projection, Shota Katori,Shun Hamada,Emi Fukuda,Shigeyuki Esumi,Yukiko Noguchi,Hideko Yamamoto,Toshifumi Yamamoto,Takeshi Yagi, NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, Vol. 58, p. S87-S87, 2007
  • プロトカドヘリン‐αクラスターにおけるαC2の発現機構と分子機能の解析, 河村佳見,南ひかる,金子涼輔,平山晃斉,八木健, 生化学, 2007
  • プロトカドヘリン‐αクラスターにおける差次的発現パターンを制御するメカニズムの解析, 川口将史,遠山知子,金子涼輔,平山晃斉,河村佳見,八木健, 生化学, 2007
  • Protocadherins : classification, structures and functions, HAMADA Shun,YAGI Takeshi, Vol. 78, No. 7, p. 662-671, 2006/07
  • Fyn-FAK signal transduction is involved in the radial migration of late-generated neocortical neurons, Eiko Nakahira,Kotaro Hattori,Takeshi Yagi,Shigeki Yuasa, NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, Vol. 55, p. S237-S237, 2006
  • Transport of CNR/Pcdh alpha family proteins is controlled by a intracellular retention signal in the carboxyl-terminal region, Shun Hamada,Emi Fukuda,Shota Katori,Takeshi Yagi, NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, Vol. 55, p. S186-S186, 2006
  • Dynamics of neuronal cell death examined by FRET-based caspase indicator, SCAT, Shizue Ohsawa,Shun Hamada,Takeshi Yagi,Masayuki Miura, NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, Vol. 55, p. S121-S121, 2006
  • Haloperidol-induced catalepsy is mediated by Fyn activation and subsequent NMDA-R phosphorylation in mice striatum, Kotaro Hattori,Shigeo Uchino,Tomoko Isosaka,Shinichi Kohsaka,Takeshi Yagi,Shigeki Yuasa, NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, Vol. 55, p. S179-S179, 2006
  • カドヘリンの多様な接着レパートリー:プロトカドヘリンの蛋白質立体構造からの示唆, 森下博文,海津正賢,村田陽二,柴田直樹,宇高恵子,樋口芳樹,阿久津秀雄,山口徹,池上貴久,八木健, 日本分子生物学会年会講演要旨集, Vol. 28th, 2005/11/25
  • マウス小脳プルキンエ細胞におけるCNR/プロトカドヘリンファミリーの発現, 加藤宏幸,河村佳見,江角重行,八木健, 日本分子生物学会年会講演要旨集, Vol. 28th, 2005/11/25
  • Variations of CNR/Protocadherin-a transcripts in a single Purkinje neuron, T. Yagi,S. Esumi,Y. Kawamura,Y. Kumode,H. Kato,T. Hirabayashi, MECHANISMS OF DEVELOPMENT, ELSEVIER SCIENCE BV, Vol. 122, p. S113-S114, 2005/09
  • Protocadherin-alpha family regulates axonal sorting into glomeruli in the mouse olfactory system, S. Hasegawa,S. Hamada,Y. Kumode,S. Esumi,S. Katori,Y. Uchiyama,T. Hirabayashi,P. Mombaerts,T. Yagi, MECHANISMS OF DEVELOPMENT, ELSEVIER SCIENCE BV, Vol. 122, p. S15-S15, 2005/09
  • Structure and Function of Diversified CNR/Protocadherin Family in the Brain, MORISHITA HIROFUMI,ESUMI SHIGEYUKI,YAGI TAKESHI,YAGI TAKESHI, 細胞工学, Vol. 24, No. 8, p. 839-846-846, 2005/08
  • CNR/Pcdhαファミリータンパク質の構造-機能連関解析(Structural and functional characterization of CNR/Pcdhα family protein), 海津 正賢,森下 博文,村田 陽二,草野 清輔,樋口 芳樹,池上 貴久,八木 健, 神経化学, 日本神経化学会, Vol. 43, No. 2-3, p. 533-533, 2004/08
  • Cadherin-related neuronal receptor 1 (CNR1) has cell adhesion activity with beta 1 integrin mediated through the RGD site of CNR1 (vol 294, pg 494, 2004), T Mutoh,S Hamada,K Senzaki,Y Murata,T Yagi, EXPERIMENTAL CELL RESEARCH, ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 297, No. 1, p. 302-302, 2004/07
  • Construction of BAC library for the amphibian, Xenopus tropicalis, Ishii Y,Asakawa S,Taguchi Y,Ishibashi S,Yagi T,Shimizu N, GENES & GENETIC SYSTEMS, GENETICS SOC JAPAN, Vol. 79, No. 1, p. 49-51, 2004/04
  • Fyn関連遺伝子による大脳皮質形成機構 (神経回路の機能発現のメカニズム) -- (シナプス可塑性と神経回路形成), 服部 功太郎,湯浅 茂樹,八木 健, 蛋白質核酸酵素, 共立出版, Vol. 49, No. 3, p. 425-430, 2004/02
  • Mouse embryos and chimera cloned from neural cells in the postnatal cerebral cortex., Makino H,Yamazaki Y,Hirabayashi T,Kaneko R,Hamada S,Kawamura Y,Osada T,Yanagimachi R,Yagi T, Cloning Stem Cells, Vol. 6, No. 4, p. 44-60, 2004
  • 3P229 Sample preparation and structural analysis of CNR/Protocadherin alpha ectodomain, Morishita H,Shibata N,Umitsu M,Murata Y,Ikegami T,Yagi T,Higuchi Y, Seibutsu Butsuri, 一般社団法人 日本生物物理学会, Vol. 44, No. 0, 2004
  • 体細胞クローン技術を用いたマウス神経細胞核における多分化能獲得の検討, 河村佳見,長田智治,牧野初音,八木健, 日本分子生物学会年会プログラム・講演要旨集, Vol. 26th, 2003/11/25
  • 条件付けされたFyn欠損マウスの情動に関わる脳の領域では恐怖反応によるc-Fos発現が増強している(大学院修了者研究報告I,第1042回千葉医学会例会・第19回千葉精神科集談会), 久保田統,橋本謙二,伊豫雅臣,湯浅茂樹,服部功太郎,八木健, 千葉医学雑誌, 千葉大学, Vol. 78, No. 5, p. 238-238, 2002/10/01
  • The cadherin-related neuronal receptor (CNR) family: a novel diversified cadherin family at the synapse., Hamada S,Yagi T, NEUROSCIENCE RESEARCH, ELSEVIER SCI IRELAND LTD, Vol. 41, No. 3, p. 207-215, 2001/11
  • Assessment of the developmental totipotency of neural cells in the cerebral cortex of mouse embryo by nuclear transfer., Yamazaki Y,Makino H,Hamaguchi-Hamada K,Hamada S,Sigino H,Kawase E,Miyata T,Ogawa M,Yanagimachi R,Yagi T, Proc. Natl. Acad. Sci. USA, Vol. 98, p. 14022-14026-14026, 2001/11
  • 25. Fyn欠損マウスの抗精神病薬に対する反応の異常(第1024回千葉医学会例会・第18回千葉精神科集談会), 服部 功太郎,伊豫 雅臣,湯浅 茂樹,八木 健, 千葉医学雑誌, 千葉大学, Vol. 77, No. 5, p. 380-380, 2001/10/01
  • Somatic mutations of synaptic cadherin (CNR) transcripts in the brain, T Yagi,T Hirayama,T Yagi, JOURNAL OF NEUROCHEMISTRY, BLACKWELL SCIENCE LTD, Vol. 78, p. 118-118, 2001/09
  • Cloning mice using neuronal cells from the embryonic cerebral cortex., Y Yamazaki,H Makino,S Hamada,K Hamaguchi-Hamada,E Kawase,M Ogawa,T Yagi,R Yanagimachi, BIOLOGY OF REPRODUCTION, SOC STUDY REPRODUCTION, Vol. 64, p. 127-127, 2001
  • Changes in circadian period and morphology of the hypothalamic suprachiasmatic nucleus in fyn kinase-deficient mice, Shima, T,Yagi, T,Isojima, Y,Okumura, N,Okada, M,Nagai, K, Brain Research,870(1-2),36-43, ELSEVIER SCIENCE BV, Vol. 870, No. 1-2, p. 36-43, 2000/07
  • Genomic organization of the family of CNR cadherin genes in mice and humans., Sugino H,Hamada S,Yasuda R,Tuji A,Matsuda Y,Fujita M,Yagi T, GENOMICS, ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 63, No. 1, p. 75-87, 2000/01
  • テレンセファリン欠損マウスにおける海馬シナプス伝達長期増強発現のこう進と学習能力の向上, 中村和裕,真鍋俊也,間宮隆吉,渡辺雅彦,森寿,八木健,市川量一,城山優治,三品昌美, 日本神経科学大会プログラム・抄録集, Vol. 22nd, 1999
  • マウス精子形成過程におけるFynチロシンキナーゼの機能解析, 前川真見子,湯浅茂樹,安田昌弘,八木健,甲斐信行, 生理学研究所年報, Vol. 20, 1999
  • Analysis of mice defective in a telencephalon-specific cell adhesion molecule, telencephalin, NAKAMURA Kazuhiro,MORI Hisashi,KIYAMA Yuji,SANBO Makoto,YAGI Takeshi,MANABE Toshiya,TAKAHASHI Tomoyuki,WATANABE Masahiko,ICHIKAWA Ryoichi,INOUE Yoshiro,MISHINA Masayoshi, Vol. 21, 1998/12/01
  • Preparation of mice carrying a inducible recombinant Cre recombinase gene integrated into the cerebellar Purkinje-cell specific GluRδ2gene, TSUJITA M.,TAKEUCHI T.,YAGI T.,MORI H.,MISHINA M., Vol. 21, p. 652-652, 1998/12/01
  • CNR family : Fyn-binding cadherin in synapse, YAGI Takeshi, Vol. 21, p. 173-173, 1998/12/01
  • Localization of the active form of Src family proteins and their target protein, Sam68 in normal mitotic cells, OWADA K.,SAKAI T.,TACHIBANA M.,MURATA T.,KOUJIN T.,KAWABE T.,MATSUMOTO N.,NISHIDA M.,KAWAKATSU H.,YASUDA M.,YAGI T.,HARAGUCHI T.,HIRAOKA Y., Vol. 21, p. 495-495, 1998/12/01
  • 終脳特異的細胞接着分子テレンセファリン欠損マウスの解析, 中村和裕,森寿,城山優治,三宝誠,八木健,真鍋俊也,高橋智幸,渡辺雅彦,三品昌美, 日本分子生物学会年会プログラム・講演要旨集, Vol. 21st, 1998
  • Neuropilin-semaphorin III/D-mediated Chemorepulsive Signals Play a Crucial Role in Peripheral Nerve Projection in Mice, FUJISAWA Hajime,KITSUKAWA Takashi,SHIMIZU Masayuki,HIRATA Tatsumi,BEKKU Yoko,YAGI Takeshi, Vol. 46, 1997/12/01
  • Physiological significance of the cytoplasmic domain of the NMDA receptor channel ε2 subunit., 森寿,中村和裕,真鍋俊也,鈴木紀光,渡辺雅彦,和田志麻,八木健,崎村建司,三品昌美, 日本分子生物学会年会プログラム・講演要旨集, Vol. 20th, 1997
  • Physiological significance of the cytoplasmic domain of the NMDA receptor channel ε2 subunit., 森寿,中村和裕,真鍋俊也,鈴木紀光,渡辺雅彦,和田志麻,八木健,崎村建司,三品昌美, 日本分子生物学会年会プログラム・講演要旨集, Vol. 20th, 1997
  • Living and death of nerve cells. Birth of nerve cells. Heredity of cerebral functions., 八木健,甲斐信行,安田昌弘, 現代化学増刊, Vol. 32, 1997
  • Increased fearfulness and enhanced seizure susceptibility of Fyn tyrosine kinase deficient mice, H Niki,T Miyakawa,T Yagi, INTERNATIONAL JOURNAL OF PSYCHOLOGY, PSYCHOLOGY PRESS, Vol. 31, No. 3-4, p. 3843-3843, 1996
  • 遺伝子タ-ゲティングによる脳機能解析(遺伝子操作による脳機能解析) (分子から高次脳機能へ--脳の階層性をふまえて) -- (分子的アプロ-チ), 八木 健, 蛋白質核酸酵素, 共立出版, Vol. 40, No. 6, p. p599-608, 1995/04
  • チロシンキナーゼ欠失マウスの恐怖反応の亢進(日本動物心理学会第54回大会発表要旨), 宮川 剛,二木 宏明,八木 健, 動物心理学研究, 日本動物心理学会, Vol. 44, No. 1, p. 55-55, 1995/03/25
  • Behavioral genetics by gene targeting., 八木健,安田昌弘,甲斐信行, 実験医学, Vol. 12, No. 19, 1994

Publications

  • Role of clustered protocadherins in promoting neuronal diversity and function, Yagi T, Elsevier, ISBN:9780128007815, 2015/09
  • Ethanol sensitivity and molecular function of Fyn tyrosine kinase., Yagi T,Yasuda M,Niki H, CSR incorporated, in Washington, DC., 2001/01
  • ジーンターゲティングの最新技術 （執筆担当：第２章BACベクターライブラリーを用いたゲノム解析法）, 八木健,杉野英彦,濱田俊,その他, 羊土社, 2000/04

Industrial Property Rights

  • 細胞系譜生成方法、プログラム、及び細胞系譜生成装置, 八木 健,内村 有邦,佐藤 康成,松本 拡高, 特許第7355325号, 特願2019-139833, 出願日:2019/07/30, 登録日:2023/09/25
  • ネットワーク分析方法、ネットワーク分析システム及びサーバ, 合田 徳夫,田中 毅,八木 健, 特願2022-009327, 出願日:2022/01/25
  • ネットワーク分析方法、ネットワーク分析システム及びサーバ, 合田 徳夫,田中 毅,八木 健, 特願2022-009334, 出願日:2022/01/25
  • さえずり変異マウス, 内村有邦,八木健,日高裕子,古澤満, 特願2008-52705, 出願日:2008/03
  • 細胞系譜生成方法、及び細胞系譜生成装置, 八木健,内村有邦,佐藤康成,松本拡高, 特願2019-139833, 出願日:2019/07
  • 特徴抽出装置、特徴抽出方法、及び、そのプログラム, 木津川尚史,八木 健, 2010-234064, 出願日:2010/10
  • さえずり変異マウス, 八木健,内村有邦,日高裕子,古澤満, PCT/JP2009/000924, 出願日:2009/03
  • 水溶性近赤外蛍光材料およびマルチモーダル水溶性近赤外蛍光材料, 神 隆,吉岡芳親,駒井豊,大澤五住,八木 健,金子凉輔,精山明敏,関 淳二, 特願2008-130884号, 出願日:2008/05
  • さえずり変異マウス, 内村有邦,八木健,日高裕子,古澤満, 特願2008-052705, 出願日:2008/03
  • プロトカドヘリンαを用いた精神神経疾患モデル動物およびその利用, 八木 健,濱田 俊,福田絵美, 特願2006-195401, 出願日:2006/07
  • プロトカドヘリンの新規機能ドメイン, 八木 健,池上貴久,森下博文,海津正賢, 特願2005-117294, 出願日:2005/04
  • 核移植技術による胚性幹細胞, 八木 健,長田智治, 特願2005-77327, 出願日:2005/03

Awards

  • 加藤淑裕記念賞, 八木 健, 日本発生生物学会, 1993/12

Media Coverage

  • 発生初期の神経細胞 DNAメチル化が関与, 日刊工業新聞, 2014/04
  • 神経細胞の個性化や回路形成でDnmt3bによるエピジェネ制御が重要, 日経バイオテク, 2014/04
  • 脳神経つなぐたんぱく質 阪大グループ特定 記憶などの仕組みに関係, 読売新聞, 2012/08
  • 小鳥のように鳴くマウス ピピピ 言語進化研究に, 共同通信、東京新聞、西日本新聞など, 2011/07
  • ”進化”解き明かすヒント？, NHK総合テレビ「ニューステラス関西（NHK大阪）, 2011/01
  • ピピピッとさえずるマウス、遺伝子操作で誕生, 読売新聞, 2010/12
  • SINGING MOUSE' MADE WITH GENETIC MODIFICATION, Discovery News, 2010/12
  • Singing Mouse: A New Phenomenon? Not According to 1936 TIME Article, TIME, 2010/12
  • 小鳥のように「ピピッ」と鳴くマウス、阪大が繁殖に成功 言語の起源解明に一役, 産経ニュース, 2010/11
  • 大阪大学、ネオモルガン研究所、進化を加速する技術を利用して変異マウスを作製、小鳥のように鳴くマウスも誕生, Biotechnology Japan, 2010/09

Academic Activities

  • 大阪大学基礎工学部 第40回公開講座, 大阪大学基礎工学部, 2018/08 -
  • 第39回日本神経科学大会, 2016/07 -
  • サテライトシンポジウム, 東京工業大学地球生命研究所(ELSI), 2016/07 -
  • 比較記憶研究会「異なる動物種間での記憶回路制御機構の総合的理解による記憶回路原理の解明」, 生理学研究所, 2015/10 -
  • 第5回CiNetシンポジウム/COIシンポジウム 「人間力・社会力の脳科学 脳の長所を伸ばし、脳の弱点を補強する最新技術」, 2015/06 -
  • 自然科学研究機構プロジェクト 合同シンポジウム, 生理学研究所, 2015/03 -
  • 「保育・教育分野における人間行動ビッグデータ活用の方向性を探る」公開研究会, 2015/02 -
  • 第2回包括的神経グリア研究会, 2015/01 -
  • 最先端脳科学セミナー, 2014/08 -
  • 第44回(2014)新潟神経学夏期セミナー, 2014/08 -
  • 慶應大医学部システム医学教室セミナー, 2014/02 -
  • 大阪大学医学部セミナー, 2013/10 -
  • 秋の浅虫研究会ミニシンポ, 2013/10 -
  • 第８６回日本生化学会シンポジウム, 2013/09 -
  • 熊本シンポジウム2013, 2013/06 -
  • 九大セミナー, 2013/05 -
  • 新学術領域研究「大脳新皮質構築」「メゾ神経回路」合同ワークショップ, 2012/07 -
  • 生理学研究所研究会「シナプス可塑性の動作原理～分子から行動まで～」, 2012/06 -
  • 東北大学 加齢研シンポジウム －発生生物学の適応放散－, 2011/10 -
  • 東京大学 薬学部, 2010/12 -
  • 大阪大学蛋白質研究所セミナー 「神経科学と構造生物学の融合」, 2010/10 -
  • 北海道大学 医学部, 2010/06 -
  • 新潟大学 脳研究所, 2010/04 -
  • 自然科学研究機構 生理学研究所, 2010/03 -
  • 名古屋大学 医学部, 2010/01 -
  • EHARA MEMORIAL FOUDATION SYMPOSIUM-2002 "Genomic Science-Towards a New Paradigm", 上原財団, 2002/06 -
  • Tentative meeting program "Genome-Wide Approaches for Developmental Biology using Xenopus", 基礎生物学研究所, 2002/02 -