顔写真

PHOTO

Ooishi Minako
大石　美奈子
Ooishi Minako
大石　美奈子
Graduate School of Pharmaceutical Sciences　Center for Advanced Eduction and Research in Pharmaceutical Sciences, Associate Professor

Papers 21

  1. 口腔機能に着目した医歯薬連携の必要性 口腔領域の副作用に対する保険薬局の役割

    上田 幹子, 仁木 一順, 上田 紘子, 大石 美奈子, 上島 悦子

    医療薬学　Vol. 43　No. 6　p. 320-327　2017/06

    Publisher: (一社)日本医療薬学会

  2. BK-UM in patients with recurrent ovarian cancer or peritoneal cancer: a first-in-human phase-I study.

    Shingo Miyamoto, Fusanori Yotsumoto, Taeko Ueda, Tatsuya Fukami, Ayako Sanui, Kohei Miyata, Sung Ouk Nam, Satoshi Fukagawa, Takahiro Katsuta, Miyako Maehara, Haruhiko Kondo, Daisuke Miyahara, Kyoko Shirota, Toshiyuki Yoshizato, Masahide Kuroki, Hiroaki Nishikawa, Keijiro Saku, Yoshio Tsuboi, Kenji Ishitsuka, Yasushi Takamatsu, Kazuo Tamura, Akira Matsunaga, Toru Hachisuga, Shinsuke Nishino, Takashi Odawara, Kazuhiro Maeda, Sadao Manabe, Toyokazu Ishikawa, Yoshinobu Okuno, Minako Ohishi, Tomoya Hikita, Hiroto Mizushima, Ryo Iwamoto, Eisuke Mekada

    BMC cancer　Vol. 17　No. 1　p. 89-89　2017/01/31　Research paper (scientific journal)

  3. 歯科医療で薬剤師が介入し、良好な疼痛管理が可能となった症例

    北村 麻理愛, 上田 紘子, 大石 美奈子, 森 功美子, 上田 幹子

    日本薬学会年会要旨集　Vol. 135年会　No. 4　p. 79-79　2015/03

    Publisher: (公社)日本薬学会

  4. Humanized gene replacement in mice reveals the contribution of cancer stroma-derived HB-EGF to tumor growth.

    Tomoko Ichise, Satoshi Adachi, Minako Ohishi, Masahito Ikawa, Masaru Okabe, Ryo Iwamoto, Eisuke Mekada

    Cell structure and function　Vol. 35　No. 1　p. 3-13　2010　Research paper (scientific journal)

  5. Diphtheria toxin mutant CRM197 possesses weak EF2-ADP-ribosyl activity that potentiates its anti-tumorigenic activity.

    Takuya Kageyama, Minako Ohishi, Shingo Miyamoto, Hiroto Mizushima, Ryo Iwamoto, Eisuke Mekada

    Journal of biochemistry　Vol. 142　No. 1　p. 95-104　2007/07　Research paper (scientific journal)

  6. Prediction and testing of novel transcriptional networks regulating embryonic stem cell self-renewal and commitment.

    Emily Walker, Minako Ohishi, Ryan E Davey, Wen Zhang, Paul A Cassar, Tetsuya S Tanaka, Sandy D Der, Quaid Morris, Timothy R Hughes, Peter W Zandstra, William L Stanford

    Cell stem cell　Vol. 1　No. 1　p. 71-86　2007/06/07　Research paper (scientific journal)

  7. Cytoplasmic domain phosphorylation of heparin-binding EGF-like growth factor.

    Xiaobiao Wang, Hiroto Mizushima, Satoshi Adachi, Minako Ohishi, Ryo Iwamoto, Eisuke Mekada

    Cell structure and function　Vol. 31　No. 1　p. 15-27　2006　Research paper (scientific journal)

    Publisher: Japan Society for Cell Biology

  8. The Centre for Modeling Human Disease Gene Trap resource.

    Christine To, Trevor Epp, Tammy Reid, Qing Lan, Mei Yu, Carol Y J Li, Minako Ohishi, Paula Hant, Nora Tsao, Guillermo Casallo, Janet Rossant, Lucy R Osborne, William L Stanford

    Nucleic acids research　Vol. 32　No. Database issue　2004/01/01　Research paper (scientific journal)

  9. BopB is a type III secreted protein in Bordetella bronchiseptica and is required for cytotoxicity against cultured mammalian cells.

    Asaomi Kuwae, Minako Ohishi, Mineo Watanabe, Masaaki Nagai, Akio Abe

    Cellular microbiology　Vol. 5　No. 12　p. 973-83　2003/12　Research paper (scientific journal)

  10. Critical roles of Pten in B cell homeostasis and immunoglobulin class switch recombination.

    Akira Suzuki, Tsuneyasu Kaisho, Minako Ohishi, Manae Tsukio-Yamaguchi, Takeshi Tsubata, Pandelakis A Koni, Takehiko Sasaki, Tak Wah Mak, Toru Nakano

    The Journal of experimental medicine　Vol. 197　No. 5　p. 657-67　2003/03/03　Research paper (scientific journal)

    Publisher: Rockefeller University Press

  11. Keratinocyte-specific Pten deficiency results in epidermal hyperplasia, accelerated hair follicle morphogenesis and tumor formation.

    Akira Suzuki, Satoshi Itami, Minako Ohishi, Koichi Hamada, Tae Inoue, Nobuyasu Komazawa, Haruki Senoo, Takehiko Sasaki, Junji Takeda, Motomu Manabe, Tak Wah Mak, Toru Nakano

    Cancer research　Vol. 63　No. 3　p. 674-81　2003/02/01　Research paper (scientific journal)

  12. In vivo modifications of small GTPase Rac and Cdc42 by Bordetella dermonecrotic toxin.

    Minako Masuda, Masayoshi Minami, Hiroaki Shime, Takeshi Matsuzawa, Yasuhiko Horiguchi

    Infection and immunity　Vol. 70　No. 2　p. 998-1001　2002/02　Research paper (scientific journal)

  13. Supermolecular structure of the enteropathogenic Escherichia coli type III secretion system and its direct interaction with the EspA-sheath-like structure.

    K Sekiya, M Ohishi, T Ogino, K Tamano, C Sasakawa, A Abe

    Proceedings of the National Academy of Sciences of the United States of America　Vol. 98　No. 20　p. 11638-43　2001/09/25　Research paper (scientific journal)

  14. A dual signaling cascade that regulates the ectodomain shedding of heparin-binding epidermal growth factor-like growth factor.

    T Umata, M Hirata, T Takahashi, F Ryu, S Shida, Y Takahashi, M Tsuneoka, Y Miura, M Masuda, Y Horiguchi, E Mekada

    The Journal of biological chemistry　Vol. 276　No. 32　p. 30475-82　2001/08/10　Research paper (scientific journal)

  15. Bordetella bronchisepticaのタイプIII分泌機構の解析

    増田 美奈子, 渡辺 峰雄, 長井 正昭, 阿部 章夫

    日本細菌学雑誌　Vol. 56　No. 1　p. 188-188　2001/02

    Publisher: 日本細菌学会

  16. Activation of rho through a cross-link with polyamines catalyzed by Bordetella dermonecrotizing toxin.

    M Masuda, L Betancourt, T Matsuzawa, T Kashimoto, T Takao, Y Shimonishi, Y Horiguchi

    The EMBO journal　Vol. 19　No. 4　p. 521-30　2000/02/15　Research paper (scientific journal)

  17. Cytotoxic necrotizing factor type 2 produced by pathogenic Escherichia coli deamidates a gln residue in the conserved G-3 domain of the rho family and preferentially inhibits the GTPase activity of RhoA and rac1.

    M Sugai, K Hatazaki, A Mogami, H Ohta, S Y Pérès, F Hérault, Y Horiguchi, M Masuda, Y Ueno, H Komatsuzawa, H Suginaka, E Oswald

    Infection and immunity　Vol. 67　No. 12　p. 6550-7　1999/12　Research paper (scientific journal)

  18. Identification of functional domains of Bordetella dermonecrotizing toxin.

    T Kashimoto, J Katahira, W R Cornejo, M Masuda, A Fukuoh, T Matsuzawa, T Ohnishi, Y Horiguchi

    Infection and immunity　Vol. 67　No. 8　p. 3727-32　1999/08　Research paper (scientific journal)

  19. Bordetella bronchiseptica dermonecrotizing toxin induces reorganization of actin stress fibers through deamidation of Gln-63 of the GTP-binding protein Rho.

    Y Horiguchi, N Inoue, M Masuda, T Kashimoto, J Katahira, N Sugimoto, M Matsuda

    Proceedings of the National Academy of Sciences of the United States of America　Vol. 94　No. 21　p. 11623-6　1997/10/14　Research paper (scientific journal)

  20. Clostridium perfringens enterotoxin utilizes two structurally related membrane proteins as functional receptors in vivo

    J Katahira, H Sugiyama, N Inoue, Y Horiguchi, M Matsuda, N Sugimoto

    JOURNAL OF BIOLOGICAL CHEMISTRY　Vol. 272　No. 42　p. 26652-26658　1997/10　Research paper (scientific journal)

  21. Molecular cloning and functional characterization of the receptor for Clostridium perfringens enterotoxin

    J Katahira, N Inoue, Y Horiguchi, M Matsuda, N Sugimoto

    JOURNAL OF CELL BIOLOGY　Vol. 136　No. 6　p. 1239-1247　1997/03　Research paper (scientific journal)

Misc. 12

  1. Pharmacokinetics of Loxoprofen and Cefcapene following a Single Combined Dose in Healthy Volunteers before, during or Immediately after 120-min Enteral Tube Feeding of 400 mL Ensure Liquid®

    UEDA Mikiko, OKAJIMA Chisato, TEMPAKU Mamoru, FUKUDA Yuki, YOSHIDA Saki, Hirata Kazumasa, SUNA Shinichiro, KATAOKA Kazusaburo, KOGO Mikihiko, UEJIMA Etsuko, HARADA Kazuo, IKEDA Kenji, OHISHI Minako, KITAMURA Maria, UEDA Hiroko, AZENISHI Katsumi, INATSUKI Setsu, NIKI Kazunori

    Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics　Vol. 48　No. 6　p. 185-193　2017

    Publisher: The Japanese Society of Clinical Pharmacology and Therapeutics

  2. P1321-22-PM 服薬に関連する歯科トラブルと服薬指導内容に係る調剤薬局を対象としたアンケート調査研究(薬物療法(その他),ポスター発表,一般演題,医療薬学の進歩と未来-次の四半世紀に向けて-)

    上田 幹子, 上田 紘子, 戸田 史恵, 森 功美子, 大石 美奈子, 高安 敏子

    日本医療薬学会年会講演要旨集　Vol. 25　No. 0　p. 486-486　2015

    Publisher: 一般社団法人 日本医療薬学会

  3. siRNAライブラリーを用いたジフテリア毒素の作用機構に関わる宿主因子の網羅的解析

    横田 春生, 大石 美奈子, 目加田 英輔

    日本細菌学雑誌　Vol. 62　No. 1　p. 109-109　2007/02/25

  4. 角化細胞特異的PTEN欠損マウスの皮膚所見

    井上 多恵, 板見 智, 大石 美奈子, 濱田 浩一, 佐々木 雄彦, 竹田 潤二, Mak Tak Wah, 仲野 徹, 真鍋 求, 鈴木 聡

    日本研究皮膚科学会年次学術大会・総会プログラム　Vol. 29回　p. 105-105　2004/04

    Publisher: (一社)日本研究皮膚科学会

  5. 組織特異的なPTEN不活性化とT細胞トレランスの破綻 (免疫調節の分子機構)

    大石 美奈子, 仲野 徹, 鈴木 聡

    免疫　Vol. 2002　p. 85-93　2002

    Publisher: 中山書店

  6. 病原因子の宿主細胞へのデリバリーシステムとその機能 (生物間の攻撃と防御の蛋白質--毒素と生物間相互作用を見直す) -- (第4部 微生物毒素とヒトとの戦い:現状と展開)

    増田 美奈子, 阿部 章夫

    蛋白質核酸酵素　Vol. 46　No. 4　p. 512-518　2001/03

    Publisher: 共立出版

  7. Bordetella dermonecrocitizing toxin is a transglutaminase specific to Rho proteins

    MASUDA Minako, BETANCOURT Lazaro, KASHIMOTO Takashige, TAKAO Toshifumi, SHIMONISHI Yasutsugu, HORIGUCHI Yasuhiko

    Vol. 21　p. 563-563　1998/12/01

  8. Pasteurella multocida toxin and Bordetella bronchiseptica dermonecrotizing toxin elicit similar effects on cultured cells by different mechanisms.

    T Ohnishi, Y Horiguchi, M Masuda, N Sugimoto, M Matsuda

    The Journal of veterinary medical science　Vol. 60　No. 3　p. 301-5　1998/03

    Publisher: Japanese Society of Veterinary Science

  9. [The GTP-binding proteins as targets for bacterial toxins].

    M Masuda, Y Horiguchi

    Nihon saikingaku zasshi. Japanese journal of bacteriology　Vol. 52　No. 4　p. 727-34　1997/10

    Publisher: JAPANESE SOCIETY FOR BACTERIOLOGY

  10. BORDETELLA-BRONCHISEPTICA DERMONECROTIZING TOXIN STIMULATES ASSEMBLY OF ACTIN STRESS FIBERS AND FOCAL ADHESIONS BY MODIFYING THE SMALL GTP-BINDING PROTEIN-RHO

    Y HORIGUCHI, T SENDA, N SUGIMOTO, J KATAHIRA, M MATSUDA

    JOURNAL OF CELL SCIENCE　Vol. 108　p. 3243-3251　1995/10

  11. MECHANISM OF ACTION OF CLOSTRIDIUM-PERFRINGENS ENTEROTOXIN

    N SUGIMOTO, Y HORIGUCHI, M MATSUDA

    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY　Vol. 209　p. 12-AGFD　1995/04　Research paper, summary (international conference)

  12. STIMULATION OF DNA-SYNTHESIS IN OSTEOBLAST-LIKE MC3T3-E1 CELLS BY BORDETELLA-BRONCHISEPTICA DERMONECROTIC TOXIN

    Y HORIGUCHI, N SUGIMOTO, M MATSUDA

    INFECTION AND IMMUNITY　Vol. 61　No. 9　p. 3611-3615　1993/09