Deciphering state-dependent immune features from multi-layer omics data at single-cell resolution

Edahiro Ryuya, Sato Go, Naito Tatsuhiko, Shirai Yuya, Saiki Ryunosuke, Sonehara Kyuto, Tomofuji Yoshihiko, Yamamoto Kenichi, Namba Shinichi, Sasa Noah, Nagao Genta, Wang Qingbo S., Takahashi Yugo, Hasegawa Takanori, Kishikawa Toshihiro, Suzuki Ken, Liu Yu Chen, Motooka Daisuke, Takuwa Ayako, Tanaka Hiromu, Azekawa Shuhei, Japan COVID-19 Task Force, Namkoong Ho, Koike Ryuji, Kimura Akinori, Imoto Seiya, Miyano Satoru, Kanai Takanori, Fukunaga Koichi, Uemura Mamoru, Morita Takayoshi, Kato Yasuhiro, Hirata Haruhiko, Takeda Yoshito, Doki Yuichiro, Eguchi Hidetoshi, Okuzaki Daisuke, Sakakibara Shuhei, Ogawa Seishi, Kumanogoh Atsushi, Okada Yukinori

Nature Genetics　Vol. 57　No. 8　p. 1905-1921　2025/07/28

Single-cell analysis reveals immune cell abnormalities underlying the clinical heterogeneity of patients with systemic sclerosis

Shimagami Hiroshi, Nishimura Kei, Matsushita Hiroaki, Metsugi Shoichi, Kato Yasuhiro, Kawasaki Takahiro, Tsujimoto Kohei, Edahiro Ryuya, Itotagawa Eri, Naito Maiko, Kawada Shoji, Nakatsubo Daisuke, Matsukawa Kazuki, Namba-Hamano Tomoko, Inoue Kazunori, Takahashi Atsushi, Mizui Masayuki, Kato Seiya, Hikita Hayato, Nakazawa Shigeaki, Kakuta Yoichi, Konaka Hachiro, Mitsumoto Kensuke, Ishikawa Nachi, Fujimoto Jun, Higa Shinji, Omiya Ryusuke, Isaka Yoshitaka, Takehara Tetsuo, Nonomura Norio, Okada Yukinori, Hattori Kunihiro, Narazaki Masashi, Kumanogoh Atsushi, Nishide Masayuki

Nature Communications　Vol. 16　No. 1　2025/06/17

Contribution of germline and somatic mutations to risk of neuromyelitis optica spectrum disorder

Yata Tomohiro, Sato Go, Ogawa Kotaro, Naito Tatsuhiko, Sonehara Kyuto, Saiki Ryunosuke, Edahiro Ryuya, Namba Shinichi, Watanabe Mitsuru, Shirai Yuya, Yamamoto Kenichi, NamKoong Ho, Nakanishi Tomoko, Yamamoto Yuji, Hosokawa Akiko, Yamamoto Mamoru, Oguro-Igashira Eri

Cell Genomics　Vol. 5　No. 3　2025/03/12

Age-related TFEB downregulation in proximal tubules causes systemic metabolic disorders and occasional apolipoprotein A4–related amyloidosis

Nakamura Jun, Yamamoto Takeshi, Takabatake Yoshitsugu, Namba-Hamano Tomoko, Takahashi Atsushi, Matsuda Jun, Minami Satoshi, Sakai Shinsuke, Yonishi Hiroaki, Maeda Shihomi, Matsui Sho, Kawai Hideaki, Matsui Isao, Yamamuro Tadashi, Edahiro Ryuya, Takashima Seiji, Takasawa Akira, Okada Yukinori, Yoshimori Tamotsu, Ballabio Andrea, Isaka Yoshitaka

JCI Insight　Vol. 10　No. 3　2025/02/10

Enhancing the efficacy of near-infrared photoimmunotherapy through intratumoural delivery of CD44–targeting antibody–photoabsorber conjugates

Adachi Yuichi, Miyake Kotaro, Ohira Kika, Satoh Shingo, Masuhiro Kentaro, Edahiro Ryuya, Shirai Yuya, Naito Maiko, Naito Yujiro, Shiroyama Takayuki, Koyama Shohei, Hirata Haruhiko, Iwahori Kota, Nagatomo Izumi, Takeda Yoshito, Kumanogoh Atsushi

eBioMedicine　Vol. 112　2025/02/01