keyword Clono biology
Kanazawa University Graduate School of Natural Science and Technology Division of Life Sciences
2009/04 - 2012/03
Kanazawa University Graduate School of Natural Science and Technology
2007/04 - 2009/03
Kanazawa University Faculty of Pharmaceutical Sciences
2003/04 - 2007/03
JAPANESE ASSOCIATION FOR ORAL BIOLOGY
日本軟骨代謝学会
The American society for bone and mineral research
THE JAPANESE BIOCHEMICAL SOCIETY
THE JAPANESE PHARMACOLOGICAL SOCIETY
JAPANESE SOCIETY FOR BONE AND MINERAL RESEARCH
Life sciences / Molecular biology / Chlono Biology
Life sciences / Developmental biology /
Life sciences / Regenerative dentistry and dental engineering /
Life sciences / Medical biochemistry /
Life sciences / Pharmacology /
Life sciences / Oral medicine /
Life sciences / Molecular biology /
研究奨励賞
日本骨代謝学会 2025/07
大阪大学賞 若手教員部門
大阪大学 2024/11
学会奨励賞
歯科基礎医学会 2024
学会賞
高畑 佳史 日本軟骨代謝学会 2020
優秀演題賞
高畑 佳史 日本骨代謝学会 2019
日本薬理学会年会 優秀発表賞
高畑 佳史 2012
金沢大学大学院 研究科長賞
高畑 佳史 2012
日本薬学会北陸支部 大学院優秀発表賞
高畑 佳史 2010
特に優れた業績による返還免除（第一種奨学金全額免除）
日本学生支援機構 2009
Serinc5 Regulates Sequential Chondrocyte Differentiation by Inhibiting Sox9 Function in Pre-Hypertrophic Chondrocytes.
Kenji Hata, Kanta Wakamori, Akane Hirakawa-Yamamura, Sachi Ichiyama-Kobayashi, Masaya Yamaguchi, Daisuke Okuzaki, Yoshifumi Takahata, Tomohiko Murakami, Narikazu Uzawa, Takashi Yamashiro, Riko Nishimura
Journal of cellular physiology 2024/11/20 Research paper (scientific journal)
Slc26a2-mediated sulfate metabolism is significant for the tooth development
Y. Yoshida, T. Inubushi, M. Yokoyama, P. Nag, J. I. Sasaki, A. Oka, T. Murotani, R. Kani, Y. Shiraishi, H. Kurosaka, Y. Takahata, R. Nishimura, S. Imazato, P. Papagerakis, T. Yamashiro
Disease Models & Mechanisms 2024/11/07 Research paper (scientific journal)
Publisher: The Company of Biologists
Expression analysis of genes including Zfhx4 in mice and zebrafish reveals a temporospatial conserved molecular basis underlying craniofacial development.
Shujie Liu, Lin Xu, Makoto Kashima, Rika Narumi, Yoshifumi Takahata, Eriko Nakamura, Hirotoshi Shibuya, Masaru Tamura, Yuki Shida, Toshihiro Inubushi, Yuko Nukada, Masaaki Miyazawa, Kenji Hata, Riko Nishimura, Takashi Yamashiro, Junichi Tasaki, Hiroshi Kurosaka
Developmental dynamics : an official publication of the American Association of Anatomists 2024/09/25 Research paper (scientific journal)
Chromatin profiling identifies chondrocyte-specific Sox9 enhancers important for skeletal development.
Sachi Ichiyama-Kobayashi, Kenji Hata, Kanta Wakamori, Yoshifumi Takahata, Tomohiko Murakami, Hitomi Yamanaka, Hiroshi Takano, Ryoji Yao, Narikazu Uzawa, Riko Nishimura
JCI insight Vol. 9 No. 11 2024/06/10 Research paper (scientific journal)
HOXA10 promotes Gdf5 expression in articular chondrocytes.
Tomohiko Murakami, Lerdluck Ruengsinpinya, Yoshifumi Takahata, Yuri Nakaminami, Kenji Hata, Riko Nishimura
Scientific reports Vol. 13 No. 1 p. 22778-22778 2023/12/20 Research paper (scientific journal)
Semaphorin 4D induces articular cartilage destruction and inflammation in joints by transcriptionally reprogramming chondrocytes
Tomohiko Murakami, Yoshifumi Takahata, Kenji Hata, Kosuke Ebina, Katsutoshi Hirose, Lerdluck Ruengsinpinya, Yuri Nakaminami, Yuki Etani, Sachi Kobayashi, Takashi Maruyama, Hiroyasu Nakano, Takehito Kaneko, Satoru Toyosawa, Hiroshi Asahara, Riko Nishimura
Science Signaling Vol. 15 No. 758 2022/11 Research paper (scientific journal)
Publisher: American Association for the Advancement of Science (AAAS)
Transcriptional regulation of FRZB in chondrocytes by Osterix and Msx2.
Hiroko Yagi, Yoshifumi Takahata, Tomohiko Murakami, Yuri Nakaminami, Hiromasa Hagino, Shiori Yamamoto, Shinya Murakami, Kenji Hata, Riko Nishimura
Journal of bone and mineral metabolism 2022/06/28 Research paper (scientific journal)
Activation and Function of NLRP3 Inflammasome in Bone and Joint-Related Diseases.
Tomohiko Murakami, Yuri Nakaminami, Yoshifumi Takahata, Kenji Hata, Riko Nishimura
International journal of molecular sciences Vol. 23 No. 10 2022/05/11 Research paper (scientific journal)
Regulatory Mechanisms of Prg4 and Gdf5 Expression in Articular Cartilage and Functions in Osteoarthritis
Yoshifumi Takahata, Hiromasa Hagino, Ayaka Kimura, Mitsuki Urushizaki, Shiori Yamamoto, Kanta Wakamori, Tomohiko Murakami, Kenji Hata, Riko Nishimura
International Journal of Molecular Sciences Vol. 23 No. 9 p. 4672-4672 2022/04/23 Research paper (scientific journal)
Publisher: MDPI AG
Zfhx4 regulates endochondral ossification as the transcriptional platform of Osterix in mice.
Eriko Nakamura, Kenji Hata, Yoshifumi Takahata, Hiroshi Kurosaka, Makoto Abe, Takaya Abe, Miho Kihara, Toshihisa Komori, Sachi Kobayashi, Tomohiko Murakami, Toshihiro Inubushi, Takashi Yamashiro, Shiori Yamamoto, Haruhiko Akiyama, Makoto Kawaguchi, Nobuo Sakata, Riko Nishimura
Communications biology Vol. 4 No. 1 p. 1258-1258 2021/11/03 Research paper (scientific journal)
Smoc1 and Smoc2 regulate bone formation as downstream molecules of Runx2.
Yoshifumi Takahata, Hiromasa Hagino, Ayaka Kimura, Mitsuki Urushizaki, Sachi Kobayashi, Kanta Wakamori, Chika Fujiwara, Eriko Nakamura, Kayon Yu, Hiroshi Kiyonari, Kana Bando, Tomohiko Murakami, Toshihisa Komori, Kenji Hata, Riko Nishimura
Communications biology Vol. 4 No. 1 p. 1199-1199 2021/10/19 Research paper (scientific journal)
The cell surface hyaluronidase TMEM2 plays an essential role in mouse neural crest cell development and survival
Toshihiro Inubushi, Yuichiro Nakanishi, Makoto Abe, Yoshifumi Takahata, Riko Nishimura, Hiroshi Kurosaka, Fumitoshi Irie, Takashi Yamashiro, Yu Yamaguchi
2021/08/12
Publisher: Cold Spring Harbor Laboratory
Dmrt2 promotes transition of endochondral bone formation by linking Sox9 and Runx2.
Koichiro Ono, Kenji Hata, Eriko Nakamura, Shota Ishihara, Sachi Kobayashi, Masako Nakanishi, Michiko Yoshida, Yoshifumi Takahata, Tomohiko Murakami, Seiichi Takenoshita, Toshihisa Komori, Riko Nishimura, Toshiyuki Yoneda
Communications biology Vol. 4 No. 1 p. 326-326 2021/03/11 Research paper (scientific journal)
G protein subunit β1 is an important mediator of the late stage of endochondral ossification.
Lerdluck Ruengsinpinya, Tomohiko Murakami, Eriko Nakamura, Yoshifumi Takahata, Kenji Hata, Yuri Nakaminami, Hiroaki Okae, Riko Nishimura
Biochemical and biophysical research communications Vol. 533 No. 1 p. 90-96 2020/09/11 Research paper (scientific journal)
Role of interleukin-1 and inflammasomes in oral disease.
Tomohiko Murakami, Yoshifumi Takahata, Kenji Hata, Riko Nishimura
Journal of oral biosciences 2020/08/06 Research paper (scientific journal)
Molecular Mechanisms Involved in the Progression and Protection of Osteoarthritis.
Yoshifumi Takahata, Tomohiko Murakami, Kenji Hata, Riko Nishimura
Current molecular pharmacology 2020/04/17 Research paper (scientific journal)
Role of Signal Transduction Pathways and Transcription Factors in Cartilage and Joint Diseases.
Riko Nishimura, Kenji Hata, Yoshifumi Takahata, Tomohiko Murakami, Eriko Nakamura, Maki Ohkawa, Lerdluck Ruengsinpinya
International journal of molecular sciences Vol. 21 No. 4 2020/02/17 Research paper (scientific journal)
Cutting Edge: G Protein Subunit β 1 Negatively Regulates NLRP3 Inflammasome Activation.
Murakami T, Ruengsinpinya L, Nakamura E, Takahata Y, Hata K, Okae H, Taniguchi S, Takahashi M, Nishimura R
Journal of immunology (Baltimore, Md. : 1950) Vol. 202 No. 7 p. 1942-1947 2019/04 Research paper (scientific journal)
Publisher: The American Association of Immunologists
Sox4 is involved in osteoarthritic cartilage deterioration through induction of ADAMTS4 and ADAMTS5.
Takahata Y, Nakamura E, Hata K, Wakabayashi M, Murakami T, Wakamori K, Yoshikawa H, Matsuda A, Fukui N, Nishimura R
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Vol. 33 No. 1 p. 619-630 2019/01 Research paper (scientific journal)
Publisher: Wiley
[ASBMR topics from basic research.]
Takahata Y, Nishimura R
Clinical calcium Vol. 29 No. 1 p. 104-107 2019
Interaction of LEF1 with TAZ is necessary for the osteoblastogenic activity of Wnt3a.
Kida J, Hata K, Nakamura E, Yagi H, Takahata Y, Murakami T, Maeda Y, Nishimura R
Scientific reports Vol. 8 No. 1 2018/07 Research paper (scientific journal)
Publisher: Springer Science and Business Media LLC
Transcriptional network systems in cartilage development and disease
Riko Nishimura, Kenji Hata, Eriko Nakamura, Tomohiko Murakami, Yoshifumi Takahata
Histochemistry and Cell Biology Vol. 149 No. 4 p. 353-363 2018/04/01
Publisher: Springer Verlag
Regulation of Cartilage Development and Diseases by Transcription Factors.
Nishimura R, Hata K, Takahata Y, Murakami T, Nakamura E, Yagi H
Journal of bone metabolism Vol. 24 No. 3 p. 147-153 2017/08 Research paper (scientific journal)
Publisher: The Korean Society of Bone Metabolism (KAMJE)
Transcriptional Network Controlling Endochondral Ossification.
Hata K, Takahata Y, Murakami T, Nishimura R
Journal of bone metabolism Vol. 24 No. 2 p. 75-82 2017/05
The Intrinsic Microglial Clock System Regulates Interleukin-6 Expression
Ryota Nakazato, Shogo Hotta, Daisuke Yamada, Miki Kou, Saki Nakamura, Yoshifumi Takahata, Hajime Tei, Rika Numano, Akiko Hida, Shigeki Shimba, Michihiro Mieda, Eiichi Hinoi, Yukio Yoneda, Takeshi Takarada
GLIA Vol. 65 No. 1 p. 198-208 2017/01 Research paper (scientific journal)
Transcriptional Modulator Ifrd1 Regulates Osteoclast Differentiation through Enhancing the NF-kappa B/NFATc1 Pathway
Takashi Iezaki, Kazuya Fukasawa, Gyujin Park, Tetsuhiro Horie, Takashi Kanayama, Kakeru Ozaki, Yuki Onishi, Yoshifumi Takahata, Yukari Nakamura, Takeshi Takarada, Yukio Yoneda, Takashi Nakamura, Jean Vacher, Eiichi Hinoi
MOLECULAR AND CELLULAR BIOLOGY Vol. 36 No. 19 p. 2451-2463 2016/10 Research paper (scientific journal)
ATF3 controls proliferation of osteoclast precursor and bone remodeling
Kazuya Fukasawa, Gyujin Park, Takashi Iezaki, Tetsuhiro Horie, Takashi Kanayama, Kakeru Ozaki, Yuki Onishi, Yoshifumi Takahata, Yukio Yoneda, Takeshi Takarada, Shigetaka Kitajima, Jean Vacher, Eiichi Hinoi
SCIENTIFIC REPORTS Vol. 6 2016/08 Research paper (scientific journal)
The Transcriptional Modulator Interferon-Related Developmental Regulator 1 in Osteoblasts Suppresses Bone Formation and Promotes Bone Resorption
Takashi Iezaki, Yuki Onishi, Kakeru Ozaki, Kazuya Fukasawa, Yoshifumi Takahata, Yukari Nakamura, Koichi Fujikawa, Takeshi Takarada, Yukio Yoneda, Yui Yamashita, Go Shioi, Eiichi Hinoi
JOURNAL OF BONE AND MINERAL RESEARCH Vol. 31 No. 3 p. 573-584 2016/03 Research paper (scientific journal)
The transcription factor Foxc1 is necessary for Ihh-Gli2-regulated endochondral ossification
Michiko Yoshida, Kenji Hata, Rikako Takashima, Koichiro Ono, Eriko Nakamura, Yoshifumi Takahata, Tomohiko Murakami, Sachiko Iseki, Teruko Takano-Yamamoto, Riko Nishimura, Toshiyuki Yoneda
NATURE COMMUNICATIONS Vol. 6 2015/03 Research paper (scientific journal)
Repression of adipogenesis through promotion of Wnt/β-catenin signaling by TIS7 up-regulated in adipocytes under hypoxia.
Nakamura Y, Hinoi E, Iezaki T, Takada S, Hashizume S, Takahata Y, Tsuruta E, Takahashi S, Yoneda Y
Biochimica et biophysica acta Vol. 1832 No. 8 p. 1117-1128 2013/08
Repression of adipogenesis through promotion of Wnt/β-catenin signaling by TIS7 up-regulated in adipocytes under hypoxia
Yukari Nakamura, Eiichi Hinoi, Takashi Iezaki, Saya Takada, Syota Hashizume, Yoshifumi Takahata, Emiko Tsuruta, Satoshi Takahashi, Yukio Yoneda
Biochimica et Biophysica Acta - Molecular Basis of Disease Vol. 1832 No. 8 p. 1117-1128 2013 Research paper (scientific journal)
The Transcription Factor Paired Box-5 Promotes Osteoblastogenesis Through Direct Induction of Osterix and Osteocalcin
Eiichi Hinoi, Eri Nakatani, Tomomi Yamamoto, Takashi Iezaki, Yoshifumi Takahata, Hiroyuki Fujita, Ryo Ishiura, Misa Takamori, Yukio Yoneda
JOURNAL OF BONE AND MINERAL RESEARCH Vol. 27 No. 12 p. 2526-2534 2012/12 Research paper (scientific journal)
Osteoclastogenesis is negatively regulated by D-serine produced by osteoblasts
Takeshi Takarada, Mika Takarada-Iemata, Yoshifumi Takahata, Daisuke Yamada, Tomomi Yamamoto, Yukari Nakamura, Eiichi Hinoi, Yukio Yoneda
JOURNAL OF CELLULAR PHYSIOLOGY Vol. 227 No. 10 p. 3477-3487 2012/10 Research paper (scientific journal)
IL-17 mediates estrogen-deficient osteoporosis in an Act1-dependent manner
Carl J. DeSelm, Yoshifumi Takahata, Julia Warren, Jean C. Chappel, Taimur Khan, Xiaoxia Li, Caini Liu, Yongwon Choi, Youngmi Faith Kim, Wei Zou, Steven L. Teitelbaum
JOURNAL OF CELLULAR BIOCHEMISTRY Vol. 113 No. 9 p. 2895-2902 2012/09 Research paper (scientific journal)
Positive Regulation by gamma-Aminobutyric Acid B Receptor Subunit-1 of Chondrogenesis through Acceleration of Nuclear Translocation of Activating Transcription Factor-4
Yoshifumi Takahata, Eiichi Hinoi, Takeshi Takarada, Yukari Nakamura, Shinya Ogawa, Yukio Yoneda
JOURNAL OF BIOLOGICAL CHEMISTRY Vol. 287 No. 40 p. 33293-33303 2012/09 Research paper (scientific journal)
The natural polyamines spermidine and spermine prevent bone loss through preferential disruption of osteoclastic activation in ovariectomized mice
Tomomi Yamamoto, Eiichi Hinoi, Hiroyuki Fujita, Takashi Iezaki, Yoshifumi Takahata, Misa Takamori, Yukio Yoneda
BRITISH JOURNAL OF PHARMACOLOGY Vol. 166 No. 3 p. 1084-1096 2012/06 Research paper (scientific journal)
Positive Regulation of Osteoclastic Differentiation by Growth Differentiation Factor 15 Upregulated in Osteocytic Cells Under Hypoxia
Eiichi Hinoi, Hiroki Ochi, Takeshi Takarada, Eri Nakatani, Takashi Iezaki, Hiroko Nakajima, Hiroyuki Fujita, Yoshifumi Takahata, Shinya Hidano, Takashi Kobayashi, Shu Takeda, Yukio Yoneda
JOURNAL OF BONE AND MINERAL RESEARCH Vol. 27 No. 4 p. 938-949 2012/04 Research paper (scientific journal)
Autophagy Proteins Regulate the Secretory Component of Osteoclastic Bone Resorption
Carl J. DeSelm, Brian C. Miller, Wei Zou, Wandy L. Beatty, Helena van Meel, Yoshifumi Takahata, Judith Klumperman, Sharon A. Tooze, Steven L. Teitelbaum, Herbert W. Virgin
DEVELOPMENTAL CELL Vol. 21 No. 5 p. 966-974 2011/11 Research paper (scientific journal)
Osteoblastic gamma-Aminobutyric Acid, Type B Receptors Negatively Regulate Osteoblastogenesis toward Disturbance of Osteoclastogenesis Mediated by Receptor Activator of Nuclear Factor kappa B Ligand in Mouse Bone
Yoshifumi Takahata, Takeshi Takarada, Eiichi Hinoi, Yukari Nakamura, Hiroyuki Fujita, Yukio Yoneda
JOURNAL OF BIOLOGICAL CHEMISTRY Vol. 286 No. 38 p. 32906-32917 2011/09 Research paper (scientific journal)
Positive Regulation by GABA(B)R1 Subunit of Leptin Expression through Gene Transactivation in Adipocytes
Yukari Nakamura, Eiichi Hinoi, Takeshi Takarada, Yoshifumi Takahata, Tomomi Yamamoto, Hiroyuki Fujita, Saya Takada, Syota Hashizume, Yukio Yoneda
PLOS ONE Vol. 6 No. 5 2011/05 Research paper (scientific journal)
Interference With Cellular Differentiation by D-Serine Through Antagonism at N-Methyl-D-Aspartate Receptors Composed of NR1 and NR3A Subunits in Chondrocytes
Takeshi Takarada, Yoshifumi Takahata, Mika Iemata, Eiichi Hinoi, Kyosuke Uno, Takao Hirai, Tomomi Yamamoto, Yukio Yoneda
JOURNAL OF CELLULAR PHYSIOLOGY Vol. 220 No. 3 p. 756-764 2009/09 Research paper (scientific journal)
Functional Expression of beta(2) Adrenergic Receptors Responsible for Protection Against Oxidative Stress Through Promotion of Glutathione Synthesis After Nrf2 Upregulation in Undifferentiated Mesenchymal C3H10T1/2 Stem Cells
Yoshifumi Takahata, Takeshi Takarada, Mika Iemata, Tomomi Yamamoto, Yukary Nakamura, Ayumi Kodama, Yukio Yoneda
JOURNAL OF CELLULAR PHYSIOLOGY Vol. 218 No. 2 p. 268-275 2009/02 Research paper (scientific journal)
Modulation of cellular proliferation and differentiation through GABA(B) receptors expressed by undifferentiated neural progenitor cells isolated from fetal mouse brain
Masaki Fukui, Noritaka Nakamichi, Masanori Yoneyama, Shusuke Ozawa, Sayumi Fujimori, Yoshifumi Takahata, Nobuhiro Nakamura, Hideo Taniura, Yukio Yoneda
JOURNAL OF CELLULAR PHYSIOLOGY Vol. 216 No. 2 p. 507-519 2008/08 Research paper (scientific journal)
Differential regulation of cellular maturation in chondrocytes and osteoblasts by glycine
Yoshifumi Takahata, Takeshi Takarada, Masato Osawa, Eiichi Hinoi, Yukari Nakamura, Yukio Yoneda
CELL AND TISSUE RESEARCH Vol. 333 No. 1 p. 91-103 2008/07 Research paper (scientific journal)
Serine racemase suppresses chondrogenic differentiation in cartilage in a Sox9-dependent manner
Takeshi Takarada, Eiichi Hinoi, Yoshifumi Takahata, Yukio Yoneda
JOURNAL OF CELLULAR PHYSIOLOGY Vol. 215 No. 2 p. 320-328 2008/05 Research paper (scientific journal)
Osteoblast protects osteoclast devoid of sodium-dependent vitamin C transporters from oxidative cytotoxicity of ascorbic acid
Takeshi Takarada, Eiichi Hinoi, Yuki Kambe, Koichi Sahara, Shintaro Kurokawa, Yoshifumi Takahata, Yukio Yoneda
EUROPEAN JOURNAL OF PHARMACOLOGY Vol. 575 No. 1-3 p. 1-11 2007/12 Research paper (scientific journal)
Possible expression of a particular gamma-aminobutyric acid transporter isoform responsive to upregulation by hyperosmolarity in rat calvarial osteoblasts
Sayumi Fujimori, Eiichi Hinoi, Takeshi Takarada, Mika Iemata, Yoshifumi Takahata, Yukio Yoneda
EUROPEAN JOURNAL OF PHARMACOLOGY Vol. 550 No. 1-3 p. 24-32 2006/11 Research paper (scientific journal)
骨軟骨形成におけるGタンパク質サブユニットβ1の機能解析
村上智彦, 高畑佳史, 波多賢二, 中南友里, 西村理行
日本骨代謝学会学術集会プログラム抄録集(CD-ROM) Vol. 40th 2022
乳酸受容体GPR81は骨における乳がん細胞の増殖を制御する
波多賢二, 高畑佳史, 村上智彦, 西村理行, 米田俊之
日本骨代謝学会学術集会プログラム抄録集(CD-ROM) Vol. 40th 2022
軟骨細胞におけるSox9遺伝子のエンハンサー領域の同定と機能解析
小林紗知, 小林紗知, 波多賢二, 高畑佳史, 村上智彦, 西村理行
日本骨代謝学会学術集会プログラム抄録集(CD-ROM) Vol. 39th 2021
GNB1(G protein subunit β1)is required for the late stage of endochondral ossification
ルゥァンシンピンヤー ルードラック, 中村恵理子, 高畑佳史, 波多賢二, 中南友里, 西村理行, 村上智彦
日本骨代謝学会学術集会プログラム抄録集(CD-ROM) Vol. 38th 2020
転写因子Runx2の新規標的遺伝子Smoc1,Smoc2による骨形成制御機構の解明
高畑佳史, 中村恵理子, 萩野弘将, 村上智彦, 波多賢二, 西村理行
日本骨代謝学会学術集会プログラム抄録集(CD-ROM) Vol. 38th 2020
転写因子Sox4はADAMTS4およびADAMTS5の発現を誘導して変形性関節症の発症に関与する
高畑佳史, 中村恵理子, 波多賢二, 若森幹太, 藤原知佳, 村上智彦, 福井尚志, 福井尚志, 西村理行
日本軟骨代謝学会プログラム・抄録集 Vol. 32nd 2019
Smoc1とSmoc2はRunx2の下流分子として骨形成を制御する
高畑佳史, 若森幹太, 藤原知佳, 中村恵理子, 漆崎海月, 木村彩花, YU Kayon, 波多賢二, 村上智彦, 西村理行
日本骨代謝学会学術集会プログラム抄録集 Vol. 37th 2019
転写制御と骨格系疾患の分子機構
波多賢二, 高畑佳史, 村上智彦, 西村理行
Journal of Oral Biosciences Supplement (Web) Vol. 2018 2018
転写因子Sox4はADAMTS4およびADAMTS5の発現を誘導して変形性関節症の発症に関与する
高畑佳史, 中村恵理子, 波多賢二, 若林真, 村上智彦, 若森幹太, 吉川浩史, 松田昭生, 福井尚志, 福井尚志, 西村理行
日本骨代謝学会学術集会プログラム抄録集 Vol. 36th 2018
転写因子Dmrt2は内軟骨性骨化におけるSox9からRunx2への分子間ネットワークを制御する
小野孝一郎, 波多賢二, 中村恵理子, 高畑佳史, 村上智彦, 西村理行, 米田俊之
日本軟骨代謝学会プログラム・抄録集 Vol. 31st 2018
転写因子による内軟骨性骨化の制御
波多賢二, 高畑佳史, 村上智彦, 西村理行
Journal of Oral Biosciences Supplement (Web) Vol. 2017 2017
Osterix-Msx2転写複合体はWntアンタゴニストFRZBの発現を制御する
八木寛子, 八木寛子, 村上智彦, 高畑佳史, 波多賢二, 西村理行, 村上伸也
日本歯周病学会会誌(Web) Vol. 59 2017
OsterixはMsx2と転写複合体を形成してWntアンタゴニストFRZBの発現を制御する
八木寛子, 八木寛子, 村上智彦, 高畑佳史, 中村恵理子, 木田淳平, 村上伸也, 波多賢二, 西村理行
日本骨代謝学会学術集会プログラム抄録集 Vol. 35th 2017
転写因子Foxc1はIhh-Gli2シグナルを促進し内軟骨性骨形成を制御する
波多 賢二, 吉田 倫子, 中村 恵理子, 高畑 佳史, 村上 智彦, 井関 祥子, 山本 照子, 西村 理行
Journal of Oral Biosciences Supplement Vol. 2015 p. 169-169 2015/09
Publisher: (一社)歯科基礎医学会転写因子Zfhx4はOsterixと結合して内軟骨性骨形成の後期過程を制御する
中村 恵理子, 波多 賢二, 吉田 倫子, 村上 智彦, 高畑 佳史, 阿部 真土, 米田 俊之, 西村 理行
日本骨代謝学会学術集会プログラム抄録集 Vol. 33回 p. 162-162 2015/07
Publisher: (一社)日本骨代謝学会
BMP2は転写因子OsterixとMsx2を介して変形性関節症の創薬ターゲット,WntアンタゴニストFRZBの発現を制御する
八木寛子, 高畑佳史, 村上智彦, 波多賢二, 西村理行
Journal of Oral Biosciences Supplement (Web) Vol. 2015 2015
慢性炎症に関連するNLRP3インフラマソームの活性化機構の解析
村上智彦, 高畑佳史, 波多賢二, 西村理行
Journal of Oral Biosciences Supplement (Web) Vol. 2015 2015
転写因子Foxc1はIhh-Gli2シグナルを促進し内軟骨性骨形成を制御する
波多賢二, 吉田倫子, 吉田倫子, 中村恵理子, 高畑佳史, 村上智彦, 井関祥子, 山本照子, 西村理行
Journal of Oral Biosciences Supplement (Web) Vol. 2015 2015
神経変性疾患発症に関与する炎症の慢性化機構
村上智彦, 高畑佳史, 波多賢二, 西村理行
日本生物学的精神医学会誌 2014
ERK5 regulates osteoblast differentiation but not osteoclast differentiation
Yoshifumi Takahata, Eiichi Hinoi, Yukio Yoneda
JOURNAL OF PHARMACOLOGICAL SCIENCES Vol. 118 p. 70P-70P 2012 Research paper, summary (international conference)
Autophagy Proteins Regulate the Secretory Component of Osteoclastic Bone Resorption (vol 21, pg 966, 2011)
Carl J. DeSelm, Brian C. Miller, Wei Zou, Wandy L. Beatty, Eline van Meel, Yoshifumi Takahata, Judith Klumperman, Sharon A. Tooze, Steven L. Teitelbaum, Herbert W. Virgin
DEVELOPMENTAL CELL Vol. 21 No. 6 p. 1179-1179 2011/12 Other
Modulation by GABABR1 subunit of cellular differentiation in chondrocytes
Yoshifumi Takahata, Takeshi Takarada, Eiichi Hinoi, Yukio Yoneda
JOURNAL OF PHARMACOLOGICAL SCIENCES Vol. 112 p. 159P-159P 2010 Research paper, summary (international conference)
MITOCHONDRIAL CALCIUM IN NMDA NEUROTOXICITY
Y. Takahata, Y. Kambe, N. Nakamichi, T. Takarada, Y. Yoneda
JOURNAL OF NEUROCHEMISTRY Vol. 110 p. 130-130 2009/09 Research paper, summary (international conference)
GABABR molecule modulates cellular maturation in osteoblasts
Yoshifumi Takahata, Takeshi Takarada, Kyosuke Uno, Sayumi Fujimori, Eiichi Hinoi, Yukio Yoneda
JOURNAL OF PHARMACOLOGICAL SCIENCES Vol. 109 p. 146P-146P 2009 Research paper, summary (international conference)
Modulation of proliferation and differentiation by GABAergic signals in murine neural progenitor cells
Y. Takahata, M. Fukui, S. Ozawa, T. Takarada, H. Taniura, N. Nakamichi, Y. Yoneda
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY Vol. 11 p. 217-217 2008/07 Research paper, summary (international conference)
Therapy for nifedipine-induced gingival overgrowth by Saireito in rats
Yoshifumi Takahata, Takeshi Takarada, Eiichi Hinoi, Yukio Yoneda
JOURNAL OF PHARMACOLOGICAL SCIENCES Vol. 106 p. 155P-155P 2008 Research paper, summary (international conference)
Characterization of ArfGAP1 and FinGER7/FinGER8 interaction by quantitative yeast two-hybrid analysis
Fukui, M, Nakamichi, N, Yoneyama, M, Ozawa, S, Fujimori, S, Takahata, Y, Nakamura, N, Taniura, H, Yoneda, Y
J. Juzen Med. Soc. Vol. 122 p. 2218-2227
Slc26a2-mediated sulfate metabolism is important in tooth development
Yoshida Yuka, Inubushi Toshihiro, Yokoyama Mika, Nag Priyanka, Sasaki Jun-Ichi, Oka Ayaka, Murotani Tomoya, Kani Renshiro, Shiraishi Yuki, Kurosaka Hiroshi, Takahata Yoshifumi, Nishimura Riko, Imazato Satoshi, Papagerakis Petros, Yamashiro Takashi
DMM Disease Models and Mechanisms Vol. 17 No. 12 2024/12/10
Serinc5 Regulates Sequential Chondrocyte Differentiation by Inhibiting Sox9 Function in Pre-Hypertrophic Chondrocytes
Hata Kenji, Wakamori Kanta, Hirakawa-Yamamura Akane, Ichiyama-Kobayashi Sachi, Yamaguchi Masaya, Okuzaki Daisuke, Takahata Yoshifumi, Murakami Tomohiko, Uzawa Narikazu, Yamashiro Takashi, Nishimura Riko
Journal of Cellular Physiology Vol. 240 No. 1 2024/11/20
Chromatin profiling identifies chondrocyte-specific Sox9 enhancers important for skeletal development
Ichiyama-Kobayashi Sachi, Hata Kenji, Wakamori Kanta, Takahata Yoshifumi, Murakami Tomohiko, Yamanaka Hitomi, Takano Hiroshi, Yao Ryoji, Uzawa Narikazu, Nishimura Riko
JCI Insight Vol. 9 No. 11 2024/06/10
