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TEX38 localizes ZDHHC19 to the plasma membrane and regulates sperm head morphogenesis in mice.
Yuki Kaneda, Yonggang Lu, Jiang Sun, Keisuke Shimada, Chihiro Emori, Taichi Noda, Takayuki Koyano, Makoto Matsuyama, Haruhiko Miyata, Masahito Ikawa
Proceedings of the National Academy of Sciences of the United States of America Vol. 122 No. 10 2025/03/11 Research paper (scientific journal)
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Trophectoderm-specific gene manipulation using adeno-associated viral vectors.
Tatsuya Nakagawa, Chihiro Emori, Masahito Ikawa
Experimental animals 2025/01/11 Research paper (scientific journal)
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Single-cell and bulk transcriptional profiling of mouse ovaries reveals novel genes and pathways associated with DNA damage response in oocytes.
Monique Mills, Chihiro Emori, Parveen Kumar, Zachary Boucher, Joshy George, Ewelina Bolcun-Filas
Developmental biology Vol. 517 p. 55-72 2025/01 Research paper (scientific journal)
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Age-associated aberrations of the cumulus-oocyte interaction and in the zona pellucida structure reduce fertility in female mice.
Yu Ishikawa-Yamauchi, Chihiro Emori, Hideto Mori, Tsutomu Endo, Kiyonori Kobayashi, Yuji Watanabe, Hiroshi Sagara, Takeshi Nagata, Daisuke Motooka, Akinori Ninomiya, Manabu Ozawa, Masahito Ikawa
Communications biology Vol. 7 No. 1 p. 1692-1692 2024/12/24 Research paper (scientific journal)
Publisher: Springer Science and Business Media LLC
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Inhibition of ROS1 activity with lorlatinib reversibly suppresses fertility in male mice.
Yuki Oyama, Kentaro Shimada, Haruhiko Miyata, Rie Iida-Norita, Chihiro Emori, Maki Kamoshita, Seiya Oura, Ryohei Katayama, Martin M Matzuk, Masahito Ikawa
Andrology 2024/11/20 Research paper (scientific journal)
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FBXO24 deletion causes abnormal accumulation of membraneless electron-dense granules in sperm flagella and male infertility.
Yuki Kaneda, Haruhiko Miyata, Zoulan Xu, Keisuke Shimada, Maki Kamoshita, Tatsuya Nakagawa, Chihiro Emori, Masahito Ikawa
eLife Vol. 13 2024/08/20 Research paper (scientific journal)
Publisher: eLife Sciences Publications, Ltd
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Thirteen Ovary-Enriched Genes Are Individually Not Essential for Female Fertility in Mice.
Anh Hoang Pham, Chihiro Emori, Yu Ishikawa-Yamauchi, Keizo Tokuhiro, Maki Kamoshita, Yoshitaka Fujihara, Masahito Ikawa
Cells Vol. 13 No. 10 2024/05/08 Research paper (scientific journal)
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ZP2 cleavage blocks polyspermy by modulating the architecture of the egg coat
Shunsuke Nishio, Chihiro Emori, Benjamin Wiseman, Dirk Fahrenkamp, Elisa Dioguardi, Sara Zamora-Caballero, Marcel Bokhove, Ling Han, Alena Stsiapanava, Blanca Algarra, Yonggang Lu, Mayo Kodani, Rachel E. Bainbridge, Kayla M. Komondor, Anne E. Carlson, Michael Landreh, Daniele de Sanctis, Shigeki Yasumasu, Masahito Ikawa, Luca Jovine
Cell Vol. 187 No. 6 p. 1440-1459.e24 2024/03/14 Research paper (scientific journal)
Publisher: Elsevier BV
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PABPN1L is required for maternal mRNA degradation after meiosis resumption
Chihiro Emori, Mayo Kodani, Ferheen Abbasi, Masashi Mori, Masahito Ikawa
Journal of Reproduction and Development Vol. 70 No. 1 p. 10-17 2024/02/19 Research paper (scientific journal)
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Multiple ageing effects on testicular/epididymal germ cells lead to decreased male fertility in mice
Tsutomu Endo, Kiyonori Kobayashi, Takafumi Matsumura, Chihiro Emori, Manabu Ozawa, Shimpei Kawamoto, Daisuke Okuzaki, Keisuke Shimada, Haruhiko Miyata, Kentaro Shimada, Mayo Kodani, Yu Ishikawa-Yamauchi, Daisuke Motooka, Eiji Hara, Masahito Ikawa
Communications Biology Vol. 7 No. 1 p. 16-16 2024/01 Research paper (scientific journal)
Publisher: Springer Science and Business Media LLC
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Age-related decline in spermatogenic activity accompanied with endothelial cell senescence in male mice.
Manabu Ozawa, Hideto Mori, Tsutomu Endo, Yu Ishikawa-Yamauchi, Daisuke Motooka, Chihiro Emori, Masahiro Ikawa
iScience Vol. 26 No. 12 p. 108456-108456 2023/12/15 Research paper (scientific journal)
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CHEK2 signaling is the key regulator of oocyte survival after chemotherapy.
Chihiro Emori, Zachary Boucher, Ewelina Bolcun-Filas
Science advances Vol. 9 No. 42 2023/10/20 Research paper (scientific journal)
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Generation of humanized LDHC knock-in mice as a tool to assess human LDHC-targeting contraceptive drugs.
Rie Iida-Norita, Haruhiko Miyata, Yuki Kaneda, Chihiro Emori, Taichi Noda, Tatsuya Nakagawa, Martin M Matzuk, Masahito Ikawa
Andrology Vol. 11 No. 5 p. 840-848 2023/07 Research paper (scientific journal)
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A small secreted protein NICOL regulates lumicrine-mediated sperm maturation and male fertility.
Daiji Kiyozumi, Kentaro Shimada, Michael Chalick, Chihiro Emori, Mayo Kodani, Seiya Oura, Taichi Noda, Tsutomu Endo, Martin M Matzuk, Daniel H Wreschner, Masahito Ikawa
Nature communications Vol. 14 No. 1 p. 2354-2354 2023/04/24 Research paper (scientific journal)
Publisher: Springer Science and Business Media LLC
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Gene Targeting in Mouse Embryonic Stem Cells via CRISPR/Cas9 Ribonucleoprotein (RNP)-Mediated Genome Editing.
Manabu Ozawa, Chihiro Emori, Masahito Ikawa
Methods in molecular biology (Clifton, N.J.) Vol. 2637 p. 87-97 2023/02/12 Research paper (scientific journal)
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Cooperative effects of oocytes and estrogen on the forkhead box L2 expression in mural granulosa cells in mice.
Haruka Ito, Chihiro Emori, Mei Kobayashi, Natsumi Maruyama, Wataru Fujii, Kunihiko Naito, Koji Sugiura
Scientific reports Vol. 12 No. 1 p. 20158-20158 2022/11/23 Research paper (scientific journal)
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CRISPR/Cas9-Mediated Highly Efficient Gene Targeting in Embryonic Stem Cells for Developing Gene-Manipulated Mouse Models.
Manabu Ozawa, Chihiro Emori, Masahito Ikawa
Journal of visualized experiments : JoVE Vol. 2022 No. 186 2022/08/24 Research paper (scientific journal)
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The testis-specific E3 ubiquitin ligase RNF133 is required for fecundity in mice.
Kaori Nozawa, Yoshitaka Fujihara, Darius J Devlin, Ricardo E Deras, Katarzyna Kent, Irina V Larina, Kohei Umezu, Zhifeng Yu, Courtney M Sutton, Qiuji Ye, Laura K Dean, Chihiro Emori, Masahito Ikawa, Thomas X Garcia, Martin M Matzuk
BMC biology Vol. 20 No. 1 p. 161-161 2022/07/13 Research paper (scientific journal)
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Sperm membrane proteins DCST1 and DCST2 are required for sperm-egg interaction in mice and fish.
Taichi Noda, Andreas Blaha, Yoshitaka Fujihara, Krista R Gert, Chihiro Emori, Victoria E Deneke, Seiya Oura, Karin Panser, Yonggang Lu, Sara Berent, Mayo Kodani, Luis Enrique Cabrera-Quio, Andrea Pauli, Masahito Ikawa
Communications biology Vol. 5 No. 1 p. 332-332 2022/04/07 Research paper (scientific journal)
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Expression and regulation of estrogen receptor 2 and its coregulators in mouse granulosa cells.
Chihiro Emori, Takuya Kanke, Haruka Ito, Yuki Akimoto, Wataru Fujii, Kunihiko Naito, Koji Sugiura
The Journal of reproduction and development Vol. 68 No. 2 p. 137-143 2022/04/01 Research paper (scientific journal)
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Sexual dimorphism in the meiotic requirement for PRDM9: A mammalian evolutionary safeguard
Natalie R. Powers, Beth L. Dumont, Chihiro Emori, Raman Akinyanju Lawal, Catherine Brunton, Kenneth Paigen, Mary Ann Handel, Ewelina Bolcun-Filas, Petko M. Petkov, Tanmoy Bhattacharyya
Science Advances Vol. 6 No. 43 p. eabb6606-eabb6606 2020/10/23 Research paper (scientific journal)
Publisher: American Association for the Advancement of Science (AAAS)
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Oocytes suppress FOXL2 expression in cumulus cells in mice
Chihiro Emori, Haruka Ito, Wataru Fujii, Kunihiko Naito, Koji Sugiura
Biology of Reproduction Vol. 103 No. 1 p. 85-93 2020/06/23 Research paper (scientific journal)
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CRISPR/Cas9-Mediated Genome Editing Reveals Oosp Family Genes are Dispensable for Female Fertility in Mice
Ferheen Abbasi, Mayo Kodani, Chihiro Emori, Daiji Kiyozumi, Masashi Mori, Yoshitaka Fujihara, Masahito Ikawa
Cells Vol. 9 No. 4 2020/03/28 Research paper (scientific journal)
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Effects of porcine oocytes on the expression levels of transcripts encoding glycolytic enzymes in granulosa cells
Yuta Matsuno, Asuka Onuma, Yoshie A. Fujioka, Chihiro Emori, Wataru Fujii, Kunihiko Naito, Koji Sugiura
Animal science journal = Nihon chikusan Gakkaiho Vol. 87 No. 9 p. 1114-1121 2016/09/01 Research paper (scientific journal)
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Mouse oocytes suppress miR-322-5p expression in Ovarian granulosa cells
Jun Ichi Sumitomo, Chihiro Emori, Yuta Matsuno, Mizuki Ueno, Kurenai Kawasaki, Takaho A. Endo, Katsuyuki Shiroguchi, Wataru Fujii, Kunihiko Naito, Koji Sugiura
Journal of Reproduction and Development Vol. 62 No. 4 p. 393-399 2016/08 Research paper (scientific journal)
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Oocyte-dependent activation of MTOR in cumulus cells controls the development and survival of cumulus-oocyte complexes
Jing Guo, Lanying Shi, Xuhong Gong, Mengjie Jiang, Yaoxue Yin, Xiaoyun Zhang, Hong Yin, Hui Li, Chihiro Emori, Koji Sugiura, John J. Eppig, You Qiang Su
Journal of Cell Science Vol. 129 No. 16 p. 3091-3103 2016/08 Research paper (scientific journal)
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Transcriptomic diversification of developing cumulus and mural granulosa cells in mouse ovarian follicles
Karen Wigglesworth, Kyung Bon Lee, Chihiro Emori, Koji Sugiura, John J. Eppig
Biology of Reproduction Vol. 92 No. 1 2015/01/01 Research paper (scientific journal)
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Role of oocyte-derived paracrine factors in follicular development
Chihiro Emori, Koji Sugiura
Animal Science Journal Vol. 85 No. 6 p. 627-633 2014/06
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Expression and regulation of FGF receptors in mouse granulosa cells
Saiichi Furukawa, Yuta Matsuno, Chihiro Emori, Wataru Fujii, Kunihiko Naito, Koji Sugiura
Journal of Mammalian Ova Research Vol. 31 No. 3 p. 86-92 2014 Research paper (scientific journal)
Publisher: Japanese Society of Mammalian Ova Research
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Cooperative effects of 17β-estradiol and oocyte-derived paracrine factors on the transcriptome of mouse cumulus cells
Chihiro Emori, Karen Wigglesworth, Wataru Fujii, Kunihiko Naito, John J. Eppig, Koji Sugiura
Endocrinology Vol. 154 No. 12 p. 4859-4872 2013/12/01 Research paper (scientific journal)