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Emori Chihiro
江森 千紘
Emori Chihiro
江森 千紘
Research Institute for Microbial Diseases, Assistant Professor

keyword Oocyte,Ovary

Research History 3

  1. 2021/04 - Present
    Osaka University

  2. 2019/10 - 2021/03
    Osaka university Specially appointed associated professor

  3. 2016/04 - 2019/09
    The Jackson Laboratory Postdoctral associate

Research Areas 1

  1. Life sciences / Zoological sciences /

Awards 6

  1. good presentation award

    2024/02

  2. 大阪大学賞(若手教員部門)

    江森 千紘 大阪大学 2023/11

  3. 令和5年度若手研究者業績発表会 優秀学術賞

    大阪大学 CAMaD 2023/09

  4. Excellent paper award

    Chihiro Emori, Koji Sugiura Animal Science Journal 2018

  5. 農学生命科学研究科長賞

    江森千紘 東京大学大学院 2016/03

  6. 応用動物科学専攻賞

    江森千紘 東京大学大学院 2015

Papers 30

  1. TEX38 localizes ZDHHC19 to the plasma membrane and regulates sperm head morphogenesis in mice.

    Yuki Kaneda, Yonggang Lu, Jiang Sun, Keisuke Shimada, Chihiro Emori, Taichi Noda, Takayuki Koyano, Makoto Matsuyama, Haruhiko Miyata, Masahito Ikawa

    Proceedings of the National Academy of Sciences of the United States of America Vol. 122 No. 10 2025/03/11 Research paper (scientific journal)

  2. Trophectoderm-specific gene manipulation using adeno-associated viral vectors.

    Tatsuya Nakagawa, Chihiro Emori, Masahito Ikawa

    Experimental animals 2025/01/11 Research paper (scientific journal)

  3. Single-cell and bulk transcriptional profiling of mouse ovaries reveals novel genes and pathways associated with DNA damage response in oocytes.

    Monique Mills, Chihiro Emori, Parveen Kumar, Zachary Boucher, Joshy George, Ewelina Bolcun-Filas

    Developmental biology Vol. 517 p. 55-72 2025/01 Research paper (scientific journal)

  4. Age-associated aberrations of the cumulus-oocyte interaction and in the zona pellucida structure reduce fertility in female mice.

    Yu Ishikawa-Yamauchi, Chihiro Emori, Hideto Mori, Tsutomu Endo, Kiyonori Kobayashi, Yuji Watanabe, Hiroshi Sagara, Takeshi Nagata, Daisuke Motooka, Akinori Ninomiya, Manabu Ozawa, Masahito Ikawa

    Communications biology Vol. 7 No. 1 p. 1692-1692 2024/12/24 Research paper (scientific journal)

    Publisher: Springer Science and Business Media LLC
  5. Inhibition of ROS1 activity with lorlatinib reversibly suppresses fertility in male mice.

    Yuki Oyama, Kentaro Shimada, Haruhiko Miyata, Rie Iida-Norita, Chihiro Emori, Maki Kamoshita, Seiya Oura, Ryohei Katayama, Martin M Matzuk, Masahito Ikawa

    Andrology 2024/11/20 Research paper (scientific journal)

  6. FBXO24 deletion causes abnormal accumulation of membraneless electron-dense granules in sperm flagella and male infertility.

    Yuki Kaneda, Haruhiko Miyata, Zoulan Xu, Keisuke Shimada, Maki Kamoshita, Tatsuya Nakagawa, Chihiro Emori, Masahito Ikawa

    eLife Vol. 13 2024/08/20 Research paper (scientific journal)

    Publisher: eLife Sciences Publications, Ltd
  7. Thirteen Ovary-Enriched Genes Are Individually Not Essential for Female Fertility in Mice.

    Anh Hoang Pham, Chihiro Emori, Yu Ishikawa-Yamauchi, Keizo Tokuhiro, Maki Kamoshita, Yoshitaka Fujihara, Masahito Ikawa

    Cells Vol. 13 No. 10 2024/05/08 Research paper (scientific journal)

  8. ZP2 cleavage blocks polyspermy by modulating the architecture of the egg coat

    Shunsuke Nishio, Chihiro Emori, Benjamin Wiseman, Dirk Fahrenkamp, Elisa Dioguardi, Sara Zamora-Caballero, Marcel Bokhove, Ling Han, Alena Stsiapanava, Blanca Algarra, Yonggang Lu, Mayo Kodani, Rachel E. Bainbridge, Kayla M. Komondor, Anne E. Carlson, Michael Landreh, Daniele de Sanctis, Shigeki Yasumasu, Masahito Ikawa, Luca Jovine

    Cell Vol. 187 No. 6 p. 1440-1459.e24 2024/03/14 Research paper (scientific journal)

    Publisher: Elsevier BV
  9. PABPN1L is required for maternal mRNA degradation after meiosis resumption

    Chihiro Emori, Mayo Kodani, Ferheen Abbasi, Masashi Mori, Masahito Ikawa

    Journal of Reproduction and Development Vol. 70 No. 1 p. 10-17 2024/02/19 Research paper (scientific journal)

  10. Multiple ageing effects on testicular/epididymal germ cells lead to decreased male fertility in mice

    Tsutomu Endo, Kiyonori Kobayashi, Takafumi Matsumura, Chihiro Emori, Manabu Ozawa, Shimpei Kawamoto, Daisuke Okuzaki, Keisuke Shimada, Haruhiko Miyata, Kentaro Shimada, Mayo Kodani, Yu Ishikawa-Yamauchi, Daisuke Motooka, Eiji Hara, Masahito Ikawa

    Communications Biology Vol. 7 No. 1 p. 16-16 2024/01 Research paper (scientific journal)

    Publisher: Springer Science and Business Media LLC
  11. Age-related decline in spermatogenic activity accompanied with endothelial cell senescence in male mice.

    Manabu Ozawa, Hideto Mori, Tsutomu Endo, Yu Ishikawa-Yamauchi, Daisuke Motooka, Chihiro Emori, Masahiro Ikawa

    iScience Vol. 26 No. 12 p. 108456-108456 2023/12/15 Research paper (scientific journal)

  12. CHEK2 signaling is the key regulator of oocyte survival after chemotherapy.

    Chihiro Emori, Zachary Boucher, Ewelina Bolcun-Filas

    Science advances Vol. 9 No. 42 2023/10/20 Research paper (scientific journal)

  13. Generation of humanized LDHC knock-in mice as a tool to assess human LDHC-targeting contraceptive drugs.

    Rie Iida-Norita, Haruhiko Miyata, Yuki Kaneda, Chihiro Emori, Taichi Noda, Tatsuya Nakagawa, Martin M Matzuk, Masahito Ikawa

    Andrology Vol. 11 No. 5 p. 840-848 2023/07 Research paper (scientific journal)

  14. A small secreted protein NICOL regulates lumicrine-mediated sperm maturation and male fertility.

    Daiji Kiyozumi, Kentaro Shimada, Michael Chalick, Chihiro Emori, Mayo Kodani, Seiya Oura, Taichi Noda, Tsutomu Endo, Martin M Matzuk, Daniel H Wreschner, Masahito Ikawa

    Nature communications Vol. 14 No. 1 p. 2354-2354 2023/04/24 Research paper (scientific journal)

    Publisher: Springer Science and Business Media LLC
  15. Gene Targeting in Mouse Embryonic Stem Cells via CRISPR/Cas9 Ribonucleoprotein (RNP)-Mediated Genome Editing.

    Manabu Ozawa, Chihiro Emori, Masahito Ikawa

    Methods in molecular biology (Clifton, N.J.) Vol. 2637 p. 87-97 2023/02/12 Research paper (scientific journal)

  16. Cooperative effects of oocytes and estrogen on the forkhead box L2 expression in mural granulosa cells in mice.

    Haruka Ito, Chihiro Emori, Mei Kobayashi, Natsumi Maruyama, Wataru Fujii, Kunihiko Naito, Koji Sugiura

    Scientific reports Vol. 12 No. 1 p. 20158-20158 2022/11/23 Research paper (scientific journal)

  17. CRISPR/Cas9-Mediated Highly Efficient Gene Targeting in Embryonic Stem Cells for Developing Gene-Manipulated Mouse Models.

    Manabu Ozawa, Chihiro Emori, Masahito Ikawa

    Journal of visualized experiments : JoVE Vol. 2022 No. 186 2022/08/24 Research paper (scientific journal)

  18. The testis-specific E3 ubiquitin ligase RNF133 is required for fecundity in mice.

    Kaori Nozawa, Yoshitaka Fujihara, Darius J Devlin, Ricardo E Deras, Katarzyna Kent, Irina V Larina, Kohei Umezu, Zhifeng Yu, Courtney M Sutton, Qiuji Ye, Laura K Dean, Chihiro Emori, Masahito Ikawa, Thomas X Garcia, Martin M Matzuk

    BMC biology Vol. 20 No. 1 p. 161-161 2022/07/13 Research paper (scientific journal)

  19. Sperm membrane proteins DCST1 and DCST2 are required for sperm-egg interaction in mice and fish.

    Taichi Noda, Andreas Blaha, Yoshitaka Fujihara, Krista R Gert, Chihiro Emori, Victoria E Deneke, Seiya Oura, Karin Panser, Yonggang Lu, Sara Berent, Mayo Kodani, Luis Enrique Cabrera-Quio, Andrea Pauli, Masahito Ikawa

    Communications biology Vol. 5 No. 1 p. 332-332 2022/04/07 Research paper (scientific journal)

  20. Expression and regulation of estrogen receptor 2 and its coregulators in mouse granulosa cells.

    Chihiro Emori, Takuya Kanke, Haruka Ito, Yuki Akimoto, Wataru Fujii, Kunihiko Naito, Koji Sugiura

    The Journal of reproduction and development Vol. 68 No. 2 p. 137-143 2022/04/01 Research paper (scientific journal)

  21. Sexual dimorphism in the meiotic requirement for PRDM9: A mammalian evolutionary safeguard

    Natalie R. Powers, Beth L. Dumont, Chihiro Emori, Raman Akinyanju Lawal, Catherine Brunton, Kenneth Paigen, Mary Ann Handel, Ewelina Bolcun-Filas, Petko M. Petkov, Tanmoy Bhattacharyya

    Science Advances Vol. 6 No. 43 p. eabb6606-eabb6606 2020/10/23 Research paper (scientific journal)

    Publisher: American Association for the Advancement of Science (AAAS)
  22. Oocytes suppress FOXL2 expression in cumulus cells in mice

    Chihiro Emori, Haruka Ito, Wataru Fujii, Kunihiko Naito, Koji Sugiura

    Biology of Reproduction Vol. 103 No. 1 p. 85-93 2020/06/23 Research paper (scientific journal)

  23. CRISPR/Cas9-Mediated Genome Editing Reveals Oosp Family Genes are Dispensable for Female Fertility in Mice

    Ferheen Abbasi, Mayo Kodani, Chihiro Emori, Daiji Kiyozumi, Masashi Mori, Yoshitaka Fujihara, Masahito Ikawa

    Cells Vol. 9 No. 4 2020/03/28 Research paper (scientific journal)

  24. Effects of porcine oocytes on the expression levels of transcripts encoding glycolytic enzymes in granulosa cells

    Yuta Matsuno, Asuka Onuma, Yoshie A. Fujioka, Chihiro Emori, Wataru Fujii, Kunihiko Naito, Koji Sugiura

    Animal science journal = Nihon chikusan Gakkaiho Vol. 87 No. 9 p. 1114-1121 2016/09/01 Research paper (scientific journal)

  25. Mouse oocytes suppress miR-322-5p expression in Ovarian granulosa cells

    Jun Ichi Sumitomo, Chihiro Emori, Yuta Matsuno, Mizuki Ueno, Kurenai Kawasaki, Takaho A. Endo, Katsuyuki Shiroguchi, Wataru Fujii, Kunihiko Naito, Koji Sugiura

    Journal of Reproduction and Development Vol. 62 No. 4 p. 393-399 2016/08 Research paper (scientific journal)

  26. Oocyte-dependent activation of MTOR in cumulus cells controls the development and survival of cumulus-oocyte complexes

    Jing Guo, Lanying Shi, Xuhong Gong, Mengjie Jiang, Yaoxue Yin, Xiaoyun Zhang, Hong Yin, Hui Li, Chihiro Emori, Koji Sugiura, John J. Eppig, You Qiang Su

    Journal of Cell Science Vol. 129 No. 16 p. 3091-3103 2016/08 Research paper (scientific journal)

  27. Transcriptomic diversification of developing cumulus and mural granulosa cells in mouse ovarian follicles

    Karen Wigglesworth, Kyung Bon Lee, Chihiro Emori, Koji Sugiura, John J. Eppig

    Biology of Reproduction Vol. 92 No. 1 2015/01/01 Research paper (scientific journal)

  28. Role of oocyte-derived paracrine factors in follicular development

    Chihiro Emori, Koji Sugiura

    Animal Science Journal Vol. 85 No. 6 p. 627-633 2014/06

  29. Expression and regulation of FGF receptors in mouse granulosa cells

    Saiichi Furukawa, Yuta Matsuno, Chihiro Emori, Wataru Fujii, Kunihiko Naito, Koji Sugiura

    Journal of Mammalian Ova Research Vol. 31 No. 3 p. 86-92 2014 Research paper (scientific journal)

    Publisher: Japanese Society of Mammalian Ova Research
  30. Cooperative effects of 17β-estradiol and oocyte-derived paracrine factors on the transcriptome of mouse cumulus cells

    Chihiro Emori, Karen Wigglesworth, Wataru Fujii, Kunihiko Naito, John J. Eppig, Koji Sugiura

    Endocrinology Vol. 154 No. 12 p. 4859-4872 2013/12/01 Research paper (scientific journal)

Misc. 2

  1. マウス顆粒膜細胞における線維芽細胞増殖因子受容体の発現およびその制御

    古川 最一, 松野 雄太, 江森 千紘, 藤井 渉, 内藤 邦彦, 杉浦 幸二

    Journal of mammalian ova research = 日本哺乳動物卵子学会誌 Vol. 31 No. 3 p. 86-92 2014/10

    Publisher: 日本哺乳動物卵子学会
  2. Cooperative Effects of 17 beta-Estradiol and Oocyte-Derived Paracrine Factors on the Transcriptome of Mouse Cumulus Cells (vol 154, pg 4859, 2013)

    Chihiro Emori, Karen Wigglesworth, Wataru Fujii, Kunihiko Naito, John J. Eppig, Koji Sugiura

    ENDOCRINOLOGY Vol. 155 No. 5 p. 2047-2047 2014/05 Other

Presentations 12

  1. 胎盤特異的遺伝子導入のための初期胚への新規遺伝子導入法の検討

    江森 千紘

    先端モデル動物支援プラットフォーム成果発表会 2025/02

  2. Application of Transient Gene Expression Using Lipid Nanoparticle During Early Embryo Development.

    江森 千紘

    第39回日本生殖免疫学会 2024/12

  3. 脂質ナノ粒子を用いた受精卵への新規遺伝子導入法の開発

    江森 千紘

    第47回日本分子生物学会年会 2024/11

  4. Application of Transient Gene Expression Using Lipid Nanoparticle During Early Embryo Development

    江森 千紘

    SSR 57th Annual Meeting 2024/07

  5. マウス初期胚への新規遺伝子導入法の開発

    江森 千紘

    ゲノム編集学会第9回大会 2024/06

  6. 受精卵への新規遺伝子導入法の検討

    江森千紘

    AdAMS 2023年度成果発表会 2024/02

  7. Application of lipid-nanoparticle for transient gene expression in mammalian zygotes

    2024/01

  8. Application of lipid-nanoparticle for transient gene expression in mammalian zygotes

    Chihiro Emori

    2024/01

  9. マウス受精卵への新規遺伝子導入法の開発

    江森千紘, 田中浩揮, 秋田英万, 伊川正人

    新学術領域研究 全能性プログラム 第5回公開シンポジウム 2023/12

  10. Application of lipid-encapsulated mRNA for transient gene expression in mammalian zygotes.

    江森 千紘

    56th Annual SSR Meeting 2023/07

  11. マウス受精卵への新規遺伝子導入法の開発

    江森 千紘

    第8回ゲノム編集学会 2023/06

  12. Investigating a strategy to protect reproductive health in women cancer patients.

    江森千紘

    応用動物科学セミナー 2019/09

Social Activities 1

  • 遺伝子改変技術を「知る」・「見る」・「考える」

    ナレッジキャピタル・大阪大学微生物病研究所 SpringX 超学校 高校生のためのミチシルベ 大阪大学微生物病研究所から学ぶサイエンスの仕事

    2023/08 -

Institutional Repository 1

Content Published in the University of Osaka Institutional Repository (OUKA)
  1. Inhibition of ROS1 activity with lorlatinib reversibly suppresses fertility in male mice

    Oyama Yuki, Shimada Kentaro, Miyata Haruhiko, Iida-Norita Rie, Emori Chihiro, Kamoshita Maki, Oura Seiya, Katayama Ryohei, Matzuk Martin M., Ikawa Masahito

    Andrology 2024/11/20