顔写真

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Takazaki Hiroko
髙﨑　寛子
Takazaki Hiroko
髙﨑　寛子
Institute for Protein Research, Assistant Professor

Professional Memberships 2

  1. 日本顕微鏡学会

  2. THE BIOPHYSICAL SOCIETY OF JAPAN

Research Areas 1

  1. Life sciences / Biophysics /

Papers 14

  1. Structural insights into the G protein selectivity revealed by the human EP3-Gi signaling complex.

    Ryoji Suno, Yukihiko Sugita, Kazushi Morimoto, Hiroko Takazaki, Hirokazu Tsujimoto, Mika Hirose, Chiyo Suno-Ikeda, Norimichi Nomura, Tomoya Hino, Asuka Inoue, Kenji Iwasaki, Takayuki Kato, So Iwata, Takuya Kobayashi

    Cell reports　Vol. 40　No. 11　p. 111323-111323　2022/09/13　Research paper (scientific journal)

  2. Oscillatory movement of a dynein-microtubule complex crosslinked with DNA origami.

    Shimaa A Abdellatef, Hisashi Tadakuma, Kangmin Yan, Takashi Fujiwara, Kodai Fukumoto, Yuichi Kondo, Hiroko Takazaki, Rofia Boudria, Takuo Yasunaga, Hideo Higuchi, Keiko Hirose

    eLife　Vol. 11　2022/06/24　Research paper (scientific journal)

  3. Extended supercomplex contains type-II NADH dehydrogenase, cytochrome bcc complex, and aa3 oxidase in the respiratory chain of Corynebacterium glutamicum.

    Hiroko Takazaki, Tomoichirou Kusumoto, Wataru Ishibashi, Takuo Yasunaga, Junshi Sakamoto

    Journal of bioscience and bioengineering　Vol. 133　No. 1　p. 76-82　2022/01　Research paper (scientific journal)

  4. Study on novel nano fine particles reacted with fullerene for hard to process material

    Hisayoshi Fuya, Suzuki Keisuke, Tsai Yueh-Hsun, Khajornrungruang Panart, Yasunaga Takuo, Takazaki Hiroko, Ouchi Masayoshi

    Proceedings of JSPE Semestrial Meeting　Vol. 2020S　p. 486-487　2020/03/01

    Publisher: The Japan Society for Precision Engineering

  5. Structural Analysis of KcsA by Cryo-EM Single Particle Analysis

    Takazaki Hiroko, Shimizu Hirofumi, Yasunaga Takuo

    Vol. 67　No. suppl_2　2018/11

  6. Effects of mixed ultrafine colloidal silica particles on chemical mechanical polishing of sapphire

    Bun-Athuek Natthaphon, Takazaki Hiroko, Yoshimoto Yutaka, Khajornrungruang Panart, Yasunaga Takuo, Suzuki Keisuke

    JAPANESE JOURNAL OF APPLIED PHYSICS　Vol. 57　No. 7　2018/07　Research paper (scientific journal)

  7. Study on Structure and Optimization of Hybrid Silica Particles on Chemical Mechanical Polishing of Sapphire

    Natthaphon Bun-Athuek, Hiroko Takazaki, Takuo Yasunaga, Yutaka Yoshimoto, Panart Khajornrungruang, Keisuke Suzuki

    WCMNM 2018 World Congress on Micro and Nano Manufacturing　2018

    Publisher: Research Publishing Services

  8. An Approach to Structural Analysis of a Small Membrane Protein KcsA by Cryo-electron Microscopy

    Takazaki Hiroko, Shimizu Hirofumi, Kajimura Naoko, Mitsuoka Kaoru, Yasunaga Takuo

    Microscopy　Vol. 66　No. suppl_1　2017/11　Research paper (scientific journal)

  9. Reversal of axonal growth defects in an extraocular fibrosis model by engineering the kinesin-microtubule interface

    Itsushi Minoura, Hiroko Takazaki, Rie Ayukawa, Chihiro Saruta, You Hachikubo, Seiichi Uchimura, Tomonobu Hida, Hiroyuki Kamiguchi, Tomomi Shimogori, Etsuko Muto

    NATURE COMMUNICATIONS　Vol. 7　2016/01　Research paper (scientific journal)

  10. A Mechanical Switch from Diffusion to Directional Motion Activates ATPase in Dynein Motor

    Seiichi Uchimura, Takashi Fujii, Hiroko Takazaki, Rie Ayukawa, Yosuke Nishikawa, Itsushi Minoura, You Hachikubo, Genji Kurisu, Kazuo Sutoh, Takahide Kon, Keiichi Namba, Etsuko Muto

    BIOPHYSICAL JOURNAL　Vol. 108　No. 2　p. 22A-22A　2015/01

  11. A flipped ion pair at the dynein-microtubule interface is critical for dynein motility and ATPase activation

    Seiichi Uchimura, Takashi Fujii, Hiroko Takazaki, Rie Ayukawa, Yosuke Nishikawa, Itsushi Minoura, You Hachikubo, Genji Kurisu, Kazuo Sutoh, Takahide Kon, Keiichi Namba, Etsuko Muto

    JOURNAL OF CELL BIOLOGY　Vol. 208　No. 2　p. 211-222　2015/01　Research paper (scientific journal)

  12. Overexpression, purification, and functional analysis of recombinant human tubulin dimer

    Itsushi Minoura, You Hachikubo, Yoshihiko Yamakita, Hiroko Takazaki, Rie Ayukawa, Seiichi Uchimura, Etsuko Muto

    FEBS LETTERS　Vol. 587　No. 21　p. 3450-3455　2013/11　Research paper (scientific journal)

  13. Three Outer Arm Dynein Heavy Chains of Chlamydomonas reinhardtii Operate in a Coordinated Fashion Both In Vitro and In Vivo

    Hiroko Takazaki, Zhongmei Liu, Mingyue Jin, Ritsu Kamiya, Takuo Yasunaga

    CYTOSKELETON　Vol. 67　No. 7　p. 466-476　2010/07　Research paper (scientific journal)

  14. Partially functional outer-arm dynein in a novel Chlamydomonas mutant expressing a truncated gamma heavy chain

    Zhongmei Liu, Hiroko Takazaki, Yuki Nakazawa, Miho Sakato, Toshiki Yagi, Takuo Yasunaga, Stephen M. King, Ritsu Kamiya

    EUKARYOTIC CELL　Vol. 7　No. 7　p. 1136-1145　2008/07　Research paper (scientific journal)

Misc. 20

  1. 難加工基板研磨における水酸化フラーレン結合型ハイブリッド微粒子に関する研究

    久吉楓也, 吉本裕, 高崎寛子, 安永卓生, BUN‐ATHUEK Natthaphon, KHAJORNRUNGRUANG Panart, 鈴木恵友

    砥粒加工学会学術講演会講演論文集(CD-ROM)　Vol. 2019　2019

  2. 難加工材料におけるハイブリッド研磨微粒子の最適構造に関する研究 化学的作用と機械的作用に関する考察

    鈴木恵友, NATTAPHON Bun‐Athuek, 高崎寛子, 安永卓生, 吉本裕, KHAJORNRUNGRUANG Panart

    精密工学会大会学術講演会講演論文集　Vol. 2018　2018/08/20

  3. Effects of mixed ultrafine colloidal silica particles on chemical mechanical polishing of sapphire

    Bun-Athuek Natthaphon, Takazaki Hiroko, Yoshimoto Yutaka, Khajornrungruang Panart, Yasunaga Takuo, Suzuki Keisuke

    Jpn. J. Appl. Phys.　Vol. 57　No. 7　2018/06/20

    Publisher: Institute of Physics

  4. 難加工材料向けCMPにおける結合型ハイブリッド微粒子の開発

    吉本裕, 高崎寛子, 安永卓夫, NATTHAPHON Bun‐athuek, PANART Khajornrungruang, 鈴木恵友

    砥粒加工学会学術講演会講演論文集(CD-ROM)　Vol. 2018　2018

  5. Study on the Optimization of Hybrid fine particles on Chemical Mechanical Polishing of Hard to process materials:Chemical reactivity and Mechanical action

    Suzuki Keisuke, Bun-Athuek Natthaphon, Takazaki Hiroko, Yasunaga Takuo, Yoshimoto Yutaka, Khajornrungruang Panart

    Proceedings of JSPE Semestrial Meeting　Vol. 2018　No. 0　p. 312-313　2018

    Publisher: 公益社団法人 精密工学会

  6. クライオ電子線トモグラフィー法による神経細胞糸状仮足の3次元形態とその形成メカニズム

    安永卓生, 荒牧慎二, 肥後智也, 高崎寛子

    日本解剖学会総会・全国学術集会講演プログラム・抄録集　Vol. 123rd　2018

  7. 水酸化フラーレン混合スラリーにおける吸着状態に関する研究

    吉本裕, 高崎寛子, パナート K, BUN‐ATHUEK Natthaphon, 安永卓生, 鈴木恵友

    精密工学会九州支部地方講演会講演論文集　Vol. 2017　2017/12/02

  8. 1P154 A mechanistic pivot-point in the weak-to-strong state transition during kinesin-microtubule interactions(11.Molecular motor,Poster,The 51st Annual Meeting of the Biophysical Society of Japan)

    Minoura Itsushi, Hachikubo You, Yamakita Yoshihiko, Takazaki Hiroko, Ayukawa Rie, Yoshida Chihiro, Uchimura Seiichi, Muto Etusko

    Seibutsu Butsuri　Vol. 53　No. 1　2013

    Publisher: 一般社団法人 日本生物物理学会

  9. 1P153 Structural analysis of dynein-microtubule interface : How is a signal transmitted from microtubule to AAA+ATPase domain?(11.Molecular motor,Poster,The 51st Annual Meeting of the Biophysical Society of Japan)

    Uchimura Seiichi, Sutoh Kazuo, Namba Keiichi, Muto Etsuko, Fujii Takashi, Takazaki Hiroko, Ayukawa Rie, Minoura Itsushi, Nishikawa Yosuke, Hachikubo You, Kon Takahide, Kurisu Genji

    Seibutsu Butsuri　Vol. 53　No. 1　2013

    Publisher: 一般社団法人 日本生物物理学会

  10. 1P009 Preparation of seamless 15-protofilament microtubules for helical reconstruction of microtubules(01A. Protein:Structure,Poster)

    Takazaki Hiroko, Fujii Takashi, Uchimura Seiichi, Ayukawa Rie, Namba Keiichi, Muto Etsuko

    Seibutsu Butsuri　Vol. 53　No. 1　2013

    Publisher: 一般社団法人 日本生物物理学会

  11. 1M1636 Tubulin interface for dynein motor critical for ATPase activation and motility(Molecular motor 2,The 49th Annual Meeting of the Biophysical Society of Japan)

    Uchimura Seiichi, Sutoh Kazuo, Namba Keiichi, Muto Etsuko, Fujii Takashi, Takazaki Hiroko, Ayukawa Rie, Minoura Itsushi, Nishikawa Yosuke, Hachikubo You, Kon Takahide, Kurisu Genji

    Seibutsu Butsuri　Vol. 51　No. 0　p. S65-S66　2011

    Publisher: 一般社団法人 日本生物物理学会

  12. 1P166 Structural feature of Chlamydomonas outer arm dynein(Molecular motor,The 48th Annual Meeting of the Biophysical Society of Japan)

    Takazaki Hiroko, Jin Mingyue, Yasunaga Takuo

    Seibutsu Butsuri　Vol. 50　No. 2　2010

    Publisher: 一般社団法人 日本生物物理学会

  13. 2P-066 Development of Eos: efficient 3D reconstruction of biomolecules from electron micrographs by enabling GPU computing and use of stereoscopic devices(Protein:Measurement & Analysis,The 47th Annual Meeting of the Biophysical Society of Japan)

    Azuma Ryuzo, Yoshitake Junnichi, Yasunaga Takuo, Jim Mingyue, Takazaki Hiroko, Tominaga Akito, Fukuchi Hiroaki, Ohta Koki, Shirakawa Keita, Tsukada Yoshihiro, Tsurusaki Seiya

    Seibutsu Butsuri　Vol. 49　No. 0　2009

    Publisher: 一般社団法人 日本生物物理学会

  14. 1P-133 Structure of flagellar outer dynein arm and the structural mechanism in formation of the outer dynein arm-microtubule complexes(Molecular motor, The 47th Annual Meeting of the Biophysical Society of Japan)

    Jin Mingyue, Takazaki Hiroko, Yasunaga Takuo

    Seibutsu Butsuri　Vol. 49　No. 0　2009

    Publisher: 一般社団法人 日本生物物理学会

  15. 2P-014 Configurational Interactions of Chlamydomonas Three Outer Arm Dynein Heavy Chains(Protein:Structure,The 47th Annual Meeting of the Biophysical Society of Japan)

    Takazaki Hiroko, Jin Mingyue, Yasunaga Takuo

    Seibutsu Butsuri　Vol. 49　No. 0　2009

    Publisher: 一般社団法人 日本生物物理学会

  16. Partially functional outer-arm dynein in a novel Chlamydomonas mutant expressing a truncated gamma heavy chain

    Zhongmei Liu, Hiroko Takazaki, Yuki Nakazawa, Miho Sakato, Toshiki Yagi, Takuo Yasunaga, Stephen M. King, Ritsu Kamiya

    EUKARYOTIC CELL　Vol. 7　No. 7　p. 1136-1145　2008/07

  17. 3P-143 Structure Analysis of Axonemal Dynein by Cryo-Electron Microscopy(The 46th Annual Meeting of the Biophysical Society of Japan)

    Takazaki Hiroko, Jin Mingyue, Yasunaga Takuo

    Seibutsu Butsuri　Vol. 48　No. 0　2008

    Publisher: 一般社団法人 日本生物物理学会

  18. 2P168 A Chlamydomonas Outer Arm Dynein Mutant with a Truncated Gamma Heavy Chain(Molecular motors,Poster Presentations)

    Liu Zhongmei, Takazaki Hiroko, Nakazawa Yuuki, Yagi Toshiki, Yasunaga Takuo, Kamiya Ritsu

    Seibutsu Butsuri　Vol. 47　No. 0　2007

    Publisher: 一般社団法人 日本生物物理学会

  19. 2P169 Localization, Alignment and Structure of Three Chlamydomonas Outer Arm Heavy Chains(Molecular motors,Poster Presentations)

    Takazaki Hiroko, Liu Zhongmei, Kamiya Ritsu, Yasunaga Takuo

    Seibutsu Butsuri　Vol. 47　No. 0　2007

    Publisher: 一般社団法人 日本生物物理学会

  20. 1P265 Localization of Three Chlamydomonas Outer Arm Heavy Chains(9. Molecular motor (I),Poster Session,Abstract,Meeting Program of EABS & BSJ 2006)

    Takazaki Hiroko, Liu Zhongmei, Kamiya Ritsu, Yasunaga Takuo

    Seibutsu Butsuri　Vol. 46　No. 2　2006

    Publisher: 一般社団法人 日本生物物理学会