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Nakajima Hiroo

中島 裕夫

Associate Professor

keyword Developmental Genetics,Experimental Animal Sciences,Radiation Biology

Education

  • - 1987, Osaka University
  • - 1987, Osaka University, Graduate School, Division of Medicine, Department of Biochemistry, Intitute for Cancer Research

Research History

  • 2020/06 - Present, Osaka University, Institute for Radiation Sciences, Associate Professor

Research Areas

  • Life sciences, Developmental biology
  • Environmental science/Agricultural science, Environmental policy and society
  • Environmental science/Agricultural science, Environmental impact assessment
  • Life sciences, Laboratory animal science

Professional Memberships

  • 環境科学会
  • 日本環境変異原学会
  • 日本放射線影響学会
  • 日本癌学会

Papers

  • The Reconsider Linear Non-Threshold (LNT) Hypothesis of Radiation Effect on Living Object, Yuichiro Manabe,Issei Nakamura,Hiroo Nakajima,Yuichi Tsunoyama,Masako Bando, Insights Concerning the Fukushima Daiichi Nuclear Accident Vol. 1, The Atomic Energy Society of Japan, p. 278-284, 2021
  • The Importance of Mathematical Models for Understanding the Biological Effects of Radiation: Whack-A-Mole Model and Subsequent Developments, Yuichiro Manabe,Tetsuhiro Kinugawa,Takahiro Wada,Satoshi Tanaka,Yuichi Tsunoyama,Hiroo Nakajima,Hiroshi Toki,Masako Bando, RADIOISOTOPES, Japan Radioisotope Association, Vol. 69, No. 7, p. 243-252, 2020/07/15
  • Study of mutation from DNA to biological evolution, Masako Bando,Tetsuhiro Kinugawa,Yuichiro Manabe,Miwako Masugi,Hiroo Nakajima,Kazuyo Suzuki,Yuichi Tsunoyama,Takahiro Wada,Hiroshi Toki, International Journal of Radiation Biology, Vol. 95, No. 10, p. 1390-1403, 2019/10/03
  • Verification of a dose rate-responsive dynamic equilibrium model on radiation-induced mutation frequencies in mice, Yuichi Tsunoyama,Kazuyo Suzuki,Miwako Masugi-Tokita,Hiroo Nakajima,Yuichiro Manabe,Takahiro Wada,Masako Bando, International Journal of Radiation Biology, Vol. 95, No. 10, p. 1414-1420, 2019/10/03
  • 被ばく影響の基準の根拠と健康影響に使われる解析法 放射線誘発変異発生頻度線量率応答モデルWAMモデルを用いたラッセルのマウス実験結果の再解析, 角山 雄一,鈴木 和代,馬杉 美和子,中島 裕夫,真鍋 勇一郎,和田 隆宏,坂東 昌子, 日本放射線安全管理学会誌, (一社)日本放射線安全管理学会, Vol. 17, No. 2, p. 138-140, 2018/11
  • Quantitative assessment for the effects of chronic low-dose internal Cesium-137 radiation exposure on genomic, carcinogenic and hereditary effects in mice., Hiroo Nakajima,Ohno Mizuki,Hiroshi Iahihara, 2018/04
  • Quantitative assessment for the effects of chronic low-dose internal Cesium-137 radiation exposure on genomic, carcinogenic and hereditary effects in mice., Hiroo Nakajima,Teruhisa Tsuzuki,Hiroshi Iahihar, 2017/04
  • Quantitative assessment for the effects of chronic low-dose internal Cesium-137 radiation exposure on genomic, carcinogenic and hereditary effects in mice., Hiroo Nakajima,Teruhisa Tsuzuki,Hiroshi Iahihar, 2016/04
  • Dose and dose-rate dependence of mutation frequency under long-term exposure - a new look at DDREF from WAM model, Takahiro Wada,Yuichiro Manabe,Issei Nakamura,Yuichi Tsunoyama,Hiroo Nakajima,Masako Bando, JOURNAL OF NUCLEAR SCIENCE AND TECHNOLOGY, TAYLOR & FRANCIS LTD, Vol. 53, No. 11, p. 1824-1830, 2016
  • Fukushima simulation experiment: assessing the effects of chronic low-dose-rate internal Cs-137 radiation exposure on litter size, sex ratio, and biokinetics in mice, Hiroo Nakajima,Yoshiaki Yamaguchi,Takashi Yoshimura,Manabu Fukumoto,Takeshi Todo, JOURNAL OF RADIATION RESEARCH, OXFORD UNIV PRESS, Vol. 56, No. Special Issue - Fukushima, p. I29-I35, 2015/12
  • 24aAR-10 Two component theory for quatitative estimation of damage of livin object by radiation exposure, Meeting Abstracts of the Physical Society of Japan, The Physical Society of Japan (JPS), Vol. 70, p. 3426-3426, 2015
  • Whack-A-Mole Model: Towards a Unified Description of Biological Effects Caused by Radiation Exposure, Yuichiro Manabe,Takahiro Wada,Yuichi Tsunoyama,Hiroo Nakajima,Issei Nakamura,Masako Bando, Journal of the Physical Society of Japan, Vol. 84, 044002, 2015
  • 放射線誘発突然変異頻度の線量・線量率応答への数理モデル~Whack-A-Mole モデル~の適用, 真鍋勇一郎,和田隆宏,中村一成,角山雄一,中島裕夫,坂東昌子, 放射線生物研究, Vol. 50, No. 3, p. 211-225, 2015
  • Imaging Plant Leaves to Determine Changes in Radioactive Contamination Status in Fukushima, Japan, Hiroo Nakajima,Mamoru Fujiwara,Isao Tanihata,Tadashi Saito,Norihiro Matsuda,Takeshi Todo, HEALTH PHYSICS, LIPPINCOTT WILLIAMS & WILKINS, Vol. 106, No. 5, p. 565-570, 2014/05
  • LNT再考 放射線の生体影響を考える, 真鍋 勇一郎,中村 一成,中島 裕夫,角山 雄一,坂東 昌子, 日本原子力学会誌, Vol. 56, No. 11, p. 705-706, 2014
  • How to convey the information of radiation impact correctly to the general public., Nakajima H, Radiat. Biol. Res. Commun., Vol. 46, p. 120-126, 2011/06
  • A rapid and easy method for the qualitative detection of intracellular deposition of inhaled nanoparticles,, Nakajima Hiroo,Ozaki Kiyokazu,Hongyo Tadashi,Narama, Isao,Todo Takeshi, Nanomedicine, 2011/03
  • Effects of fission neutrons on human thyroid tissues maintained in SCID mice, Shigeki Adachi,Haruko Ryo,Tadashi Hongyo,Hiroo Nakajima,Rie Tsuboi-Kikuya,Yoriko Tokita,Fumio Matsuzuka,Keizo Hiramatsu,Kazuo Fujikawa,Tetsuo Itoh,Taisei Nomura, MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS, ELSEVIER SCIENCE BV, Vol. 696, No. 2, p. 107-113, 2010/02
  • No Evidence of Increased Mutation Rates at Microsatellite Loci in Offspring of A-Bomb Survivors, M. Kodaira,H. Ryo,N. Kamada,K. Furukawa,N. Takahashi,H. Nakajima,T. Nomura,N. Nakamura, RADIATION RESEARCH, RADIATION RESEARCH SOC, Vol. 173, No. 2, p. 205-213, 2010/02
  • Differential radiation sensitivity to morphological, functional and molecular changes of human thyroid tissues and bone marrow cells maintained in SCID mice, Taisei Nomura,Tadashi Hongyo,Hiroo Nakajima,Li Ya Lia,Mukh Syaifudin,Shigeki Adachi,Haruko Ryo,Rajamanickam Baskar,Kazuyasu Fukuda,Yoshihiro Oka,Haruo Sugiyama,Fumio Matsuzuka, MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS, ELSEVIER SCIENCE BV, Vol. 657, No. 1, p. 68-76, 2008/11
  • Condensin mutations and abnormal chromosomal structures in pyothorax-associated lymphoma, Maria Francisca Ham,Tetsuya Takakuwa,Nur Rahadiani,Kristianti Tresnasari,Hiroo Nakajima,Katsuyuki Aozasa, CANCER SCIENCE, BLACKWELL PUBLISHING, Vol. 98, No. 7, p. 1041-1047, 2007/07
  • Telomere dysfunction and inactivation of the p16(INK4a)/Rb pathway in pyothorax-associated lymphoma, Kristianti Tresnasari,Tetsuya Takakuwa,Maria Francisca Ham,Nur Rahadiani,Hiroo Nakajima,Katsuyuki Aozasa, CANCER SCIENCE, BLACKWELL PUBLISHING, Vol. 98, No. 7, p. 978-984, 2007/07
  • Germ-line mutations at a mouse ESTR (Pc-3) locus and human microsatellite loci, Haruko Ryo,Hiroo Nakajima,Taisei Nomura, JOURNAL OF RADIATION RESEARCH, JAPAN RADIATION RESEARCH SOC, Vol. 47, p. B31-B37, 2006/09
  • Microsatellite mutations show no increases in the children of the Chernobyl liquidators, K Furitsu,H Ryo,KG Yeliseeva,LTT Thuy,H Kawabata,EV Krupnova,VD Trusova,VA Rzheutsky,H Nakajima,N Kartel,T Nomura, MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS, ELSEVIER SCIENCE BV, Vol. 581, No. 1-2, p. 69-82, 2005/03
  • Transgenerational transmission of radiation- and chemically induced tumors and congenital anomalies in mice: studies of their possible relationship to induced chromosomal and molecular changes, T Nomura,H Nakajima,H Ryo,LY Li,Y Fukudome,S Adachi,H Gotoh,H Tanaka, CYTOGENETIC AND GENOME RESEARCH, KARGER, Vol. 104, No. 1-4, p. 252-260, 2004
  • Effects of N-methyl-N '-nitro-N-nitrosoguanidine on the human colorectal polyps consecutively maintained in SCID mice, E Taniguchi,H Nakajima,T Hongyo,K Fukuda,LY Li,M Kurooka,H Matsuda,T Nomura, CANCER LETTERS, ELSEVIER SCI IRELAND LTD, Vol. 182, No. 2, p. 127-133, 2002/08
  • Spontaneous and radiation-induced tumorigenesis in p53-deficient mice, R Baskar,H Ryo,H Nakajima,T Hongyo,L Li,M Syaifudin,XE Si,T Nomura, RADIATION AND HOMEOSTASIS, PROCEEDINGS, ELSEVIER SCIENCE BV, Vol. 1236, p. 115-118, 2002
  • Mutations in cervical cancer as predictive factors for radiotherapy, KMY Wani,NG Huilgol,T Hongyo,H Ryo,H Nakajima,LY Li,N Chatterjee,CKK Nair,T Nomura, RADIATION AND HOMEOSTASIS, PROCEEDINGS, ELSEVIER SCIENCE BV, Vol. 1236, p. 459-461, 2002
  • Risk assessment for Medical Radiation Exposure, Nakajima H, Society of Hyogo Radiotechnologists, Vol. 62, No. 1, p. 26-74, 2002
  • Anomalous (preduodenal) portal vein: Autosomal recessive mutation in AKR/J mice, H Nakajima,LY Li,T Nomura, COMPARATIVE MEDICINE, AMER ASSOC LABORATORY ANIMAL SCIENCE, Vol. 51, No. 1, p. 22-25, 2001/02
  • Morphology and function of human benign tumors and normal thyroid tissues maintained in severe combined immunodeficient mice, K Fukuda,H Nakajima,E Taniguchi,K Sutoh,H Wang,PM Hande,LY Li,M Kurooka,K Mori,T Hongyo,T Kubo,T Nomura, CANCER LETTERS, ELSEVIER SCI IRELAND LTD, Vol. 132, No. 1-2, p. 153-158, 1998/10
  • High incidence of esophageal cancer in esophageal achalasia by the oral administration of N-amyl-N-methylnitrosamine and its prevention by nicardipine hydrochloride in mice, M Kurooka,T Hongyo,H Nakajima,R Baskar,LY Li,K Fukuda,K Sutoh,M Miyata,H Matsuda,T Nomura, CANCER LETTERS, ELSEVIER IRELAND LTD, Vol. 127, No. 1-2, p. 55-61, 1998/05
  • Dose rate effectiveness and potentially lethal damage repair in normal and double-strand break repair deficient murine cells by gamma-rays and 5-flourouracil, LY Li,H Nakajima,T Nomura, CANCER LETTERS, ELSEVIER SCI IRELAND LTD, Vol. 123, No. 2, p. 227-232, 1998/01
  • Induction of cancer, actinic keratosis, and specific p53 mutations by UVB light in human skin maintained in severe combined immunodeficient mice, T Nomura,H Nakajima,T Hongyo,E Taniguchi,K Fukuda,LY Li,M Kurooka,K Sutoh,PM Hande,T Kawaguchi,M Ueda,H Takatera, CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Vol. 57, No. 11, p. 2081-2084, 1997/06
  • Consecutive maintenance of human solitary and hereditary colorectal polyps in SCID mice, T Kawaguchi,H Nakajima,T Hongyo,K Fukuda,E Taniguchi,K Sutoh,H Wang,P Hande,LY Li,M Kurooka,T Iwasa,N Kurokawa,R Nezu,M Miyata,H Matsuda,T Nomura, CANCER DETECTION AND PREVENTION, BLACKWELL SCIENCE INC, Vol. 21, No. 2, p. 148-157, 1997
  • Cytogenotoxicities of sublimed urethane gas to the mouse embryo, T Nomura,S Tanaka,N Kurokawa,K Shibata,H Nakajima,A Kurishita,T Hongyo,Y Ishii, MUTATION RESEARCH-GENETIC TOXICOLOGY, ELSEVIER SCIENCE BV, Vol. 369, No. 1-2, p. 59-64, 1996/07
  • ENHANCEMENT OF TUMOR-GROWTH UNDER SHORT LIGHT/DARK CYCLE IN MOUSE LUNG, H NAKAJIMA,NARAMA, I,T MATSUURA,T NOMURA, CANCER LETTERS, ELSEVIER IRELAND LTD, Vol. 78, No. 1-3, p. 127-131, 1994/04
  • ESTIMATION OF STRUCTURAL-CHANGES IN THE CATARACTOUS RAT LENS USING RAMAN-SPECTROSCOPY, K HORIKIRI,H NAKAJIMA,T MATSUURA,NARAMA, I,Y FUJIMOTO,Y OZAKI, EXPERIMENTAL ANIMALS, JAPAN EXPER ANIMAL RES ASSN, Vol. 41, No. 2, p. 225-230, 1992/04
  • PROGRAMMED CELL-DEATH IN WHOLE-BODY AND ORGAN SYSTEMS BY LOW-DOSE RADIATION, T NOMURA,M KINUTA,T HONGYO,H NAKAJIMA,T HATANAKA, JOURNAL OF RADIATION RESEARCH, JAPAN RADIATION RESEARCH SOC, Vol. 33, p. 109-123, 1992/03
  • SPONTANEOUS COMBINATION (COLLISION) TUMOR IN AN ICR MOUSE, H MAEDA,K OZAKI,H NAKAJIMA,NARAMA, I, LABORATORY ANIMAL SCIENCE, AMER ASSOC LABORATORY ANIMAL SCIENCE, Vol. 41, No. 6, p. 632-634, 1991/12
  • CARCINOGENICITY OF SUBLIMED URETHANE IN MICE THROUGH THE RESPIRATORY-TRACT, T NOMURA,T HAYASHI,T MASUYAMA,S TANAKA,H NAKAJIMA,N KUROKAWA,Y ISA, JAPANESE JOURNAL OF CANCER RESEARCH, JAPANESE CANCER ASSOCIATION, Vol. 81, No. 8, p. 742-746, 1990/08
  • EMBRYONIC MUTATION AS A POSSIBLE CAUSE OF INUTERO CARCINOGENESIS IN MICE REVEALED BY POSTNATAL TREATMENT WITH 12-O-TETRADECANOYLPHORBOL-13-ACETATE, T NOMURA,H NAKAJIMA,T HATANAKA,M KINUTA,T HONGYO, CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Vol. 50, No. 7, p. 2135-2138, 1990/04
  • Inhibition of urethane-induced tumor by a synthetic insecticidal pyrethroid, d-T80-allethrin in mice, Nomura,T,Hongyo,T,Konishi,H,Fukushima,H,Nakajima,H, Cancer therapy and Control, Vol. 1, p. 51-56, 1989
  • INHIBITING EFFECTS OF NICOTINAMIDE ON URETHANE-INDUCED MALFORMATIONS AND TUMORS IN MICE, H GOTOH,T NOMURA,H NAKAJIMA,C HASEGAWA,Y SAKAMOTO, MUTATION RESEARCH, ELSEVIER SCIENCE BV, Vol. 199, No. 1, p. 55-63, 1988/05
  • Immunocytochemical characteristics and ultrastructures of immature B cells in bone marrow of rats administered IV with E. Coli and S. Typhimurium lipopolysaccharides (LPS), H. Kawaji,H. Maeda,T. Matsuura,H. Nakajima,W. Kurio,K. Manno,Y. Ogawa, International Journal of Immunopharmacology, Vol. 10, No. 1, 1988
  • Basic studies for detecting in vivo somatic mutation in mice, Nakajima H, Medical Journal of Osaka University, Vol. 39, No. 3, p. 157-163, 1987
  • CHANGING RADIATION RESPONSE OF THE DEVELOPING MOUSE EMBRYO TO SOMATIC MUTATION, H NAKAJIMA,T NOMURA, JOURNAL OF RADIATION RESEARCH, JAPAN RADIATION RESEARCH SOC, Vol. 27, No. 1, p. 81-81, 1986/03
  • STUDIES ON X-RAY-INDUCED GERM-LINE ALTERATIONS CAUSING MALFORMATIONS IN MICE, T NOMURA,H GOTOH,M KINUTA,H NAKAJIMA,S TANAKA, JOURNAL OF RADIATION RESEARCH, JAPAN RADIATION RESEARCH SOC, Vol. 27, No. 1, p. 81-81, 1986/03
  • STUDIES ON EMBRYONIC DIAPAUSE IN THE PND MUTANT OF THE SILKWORM, BOMBYX-MORI - GENETIC-CONTROL OF EMBRYOGENESIS, H SONOBE,K MAOTANI,H NAKAJIMA, JOURNAL OF INSECT PHYSIOLOGY, PERGAMON-ELSEVIER SCIENCE LTD, Vol. 32, No. 3, p. 215-&, 1986
  • Induction of tumors and malformations in mice after prenatal treatment with some antibiotic drugs, T. Nomura,S. Kimura,T. Kanzaki,H. Tanaka,K. Shibata,H. Nakajima,Y. Isa,N. Kurokawa,T. Hatanaka,M. Kinuta, Medical Journal of Osaka University, Vol. 35, No. 1-2, p. 13-17, 1984

Misc.

  • 7aAM-2 A scaling hypothesis for radiation induced mutation frequencies, Manabe Yuichiro,Nakamura Issei,Tsunoyama Yuichi,Nakajima Hiroo,Bando Masako, Meeting abstracts of the Physical Society of Japan, The Physical Society of Japan (JPS), Vol. 69, No. 2, p. 188-188, 2014/08/22
  • ASCORBIC ACID AND AHCC SUPPRESS LUNG FIBROSIS AND CANCER CAUSED BY IRRADIATION, Tadashi Hongyo,Hiroo Nakajima, JOURNAL OF THORACIC ONCOLOGY, LIPPINCOTT WILLIAMS & WILKINS, Vol. 8, p. S466-S466, 2013/11
  • Evaluation of Human Risk in Space Environment; 2009 Working Group Report., T Nomura,H Ryo,S Adachi,Y Tokita,N Horike,Y Ohira,H Nakajima,T Hongyo,K Fujikawa,T Itoh,T Ochiai,Y Katsura, Space Utiliz Res., Vol. 26,, p. 249-251, 2010
  • The tumorigenicity and genome stress in mice under the Chernobyl simulation., H. Nakajima,T. Hongyo,T. Saito,T. Todo, p. 82-82, 2009
  • Ecological decrease and biological concentration of radionuclides in plants and animals after Chernobyl catastrophe, Nakajima, H,Saito, T,Ryo, H,Nomura, T, Proceedings of the Eight Workshop on Environmental Radioactivity, Vol. 2007-16, 113-118, p. 113-118, 2008/02
  • ヒト臓器・組織置換マウス等を用いた宇宙放射線の人体および継世代リスクの基礎評価, 宇宙利用シンポジウム, Vol. 23, 298-301, 2007
  • Chromosome aberrations - Introduction, G Obe,AT Natarajan, CYTOGENETIC AND GENOME RESEARCH, KARGER, Vol. 104, No. 1-4, p. 5-6, 2004
  • A novel SCID biotechnology for biomedical studies in human, Radiobiology and Bio-medical Research (Eds. K.P. Mishra), pp200-208, Vol. pp200-208, 2004
  • P53ノックアウトマウスにおける自然および放射線誘発癌の研究, International Congress. Series, Vol. 1236, 115-118/,, 2002
  • scidマウスに継代移植されたヒト大腸ポリープへのN-4WNニトロソグアニジンによる発がん影響, Cancer Letters, Vol. 182, 127-133/,, 2002
  • 放射線と動物実験Ⅱ 放射線研究と動物実験施設, アニテックス、13:185-190, Vol. 13:185-190, 2001
  • 海外レポート「時間を売る民族と時間を買う民族」, 阪大Now, 2001
  • Apoptosis of the Thymic Lymphocytes Detected as a Membrane Change Induced by Ionising Radiation in p53 Defective Mice., Mutation Research, 2001
  • 常染色体劣性遺伝突然変異による前十二指腸門脈症, Comparative Medicine, Vol. 51, No. 1, p. 22-25, 2001
  • Biological concentration of radionuclides in plants and animals after Chernobyl catastrophe. Biological effects of low dose radiation, Institute for Environmental Sciences, 199-205,, Vol. 199-205,/,, 2000
  • Biodosimetry for detecting low dose and loe doce rate radiation., Biological effects of low dose radiation, 2000
  • 海外レポート「ベラルーシからトーブルィ ズィェン(こんにちわ)」, 阪大Now, 1999
  • ダイオキシンの遺伝的影響の問題点-継世代的影響について-, Environ. Mutagen Res., Vol. 21, p. 207-211, 1999
  • Concern for the hereditary effects of dioxins, Environ. Mutagen Res., Vol. 21, p. 207-211, 1999
  • Morphology and morphometry of the deformed cervical vertebrae in a mutant knotty-tail (knt/knt) mouse, Tetsuro Matsuura,Isao Narama,Kiyokazu Ozaki,Hiroo Nakajima,Masahiko Nishimura,Tomohiro Imagawaj,Hiroshi Kitagawa,Masato Uehara, Congenital Anomalies, Vol. 38, No. 1, p. 67-79, 1998/03
  • Morphology and morphometry of the deformed cervical vertebrae in a mutant knotty-tail (knt/knt) mouse, Tetsuro Matsuura,Isao Narama,Kiyokazu Ozaki,Hiroo Nakajima,Masahiko Nishimura,Tomohiro Imagawaj,Hiroshi Kitagawa,Masato Uehara, Congenital Anomalies, Vol. 38, No. 1, p. 67-79, 1998/03
  • Radionuclides carved on the annual rings of a tree near Chernobyl, H Nakajima,H Ryo,T Nomura,T Saito,Y Yamaguchi,KG Yeliseeva, HEALTH PHYSICS, LIPPINCOTT WILLIAMS & WILKINS, Vol. 74, No. 2, p. 265-267, 1998/02
  • チェルノブイリ近くに生育する樹木の年輪中に刻み込まれた放射性核種, Health Physics, Vol. 74, No. 2, p. 265-267, 1998
  • 食道拡張症マウスにおけるN-アミル-N-メチルニトロサミンによる高頻度誘発食道癌と塩酸ニカルジピンによるその発癌予防, Cancer Letters., Vol. 127, p. 55-61, 1998
  • ショウジョウバエおよびマウスを用いた環境有害物質の継世代的検出, 環境科学会誌, 9/(1),85-88, Vol. 9, No. (1), p. 85-88, 1996
  • ショウジョウバエおよびマウスを用いた環境有害物質の継世代的検出, 環境科学会誌, Vol. 9, No. (1), p. 85-88, 1996
  • Transgenerational Detection of Environmental Toxic Agents Effects in Drosophila and Mice, Environmental Science, Vol. 9, No. (1), p. 85-88, 1996
  • 新人為起源有害物質の継世代的人体影響, 病態生理, Vol. 14, No. 5, p. 405-408, 1995
  • Transgenerational Effects of Man-made Environmental Toxic Agents Contaminating the Earth., Vol. 14, No. 5, p. 405-408, 1995
  • 26-Week Chronic Toxicity Study and 5-Week Recovery Test of High Molecular Weight Sodium Hyaluronate (NRD101) in Rats by Intraperitoneal Administration, Matsura T,Nakajima H,Maeda H,Ozaki K,Kurio W,Uechi S,Hiramatsu Y,Ogawa Y,Ishihara R,Miyoshi T, Japanese Pharmacology & Therapeutics, Vol. 22, No. Suppl3, p. 93-134, 1994/03
  • 高分子ヒアルロン酸ナトリウム(NRD101)のラットにおける26週間腹腔内投与による慢性毒性試験および5週間の回復試験(共著), 薬理と治療 22/Suppl3,93-134, Vol. 22, No. Suppl3, p. 93-134, 1994
  • 高分子ヒアルロン酸ナトリウム(NRD101)のラットにおける妊娠前および妊娠初期投与試験(共著), 薬理と治療 22/Suppl3,173-184, Vol. 22, No. Suppl3, p. 173-184, 1994
  • 高分子ヒアルロン酸ナトリウム(NRD101)のラットにおける周産期および授乳期投与試験(共著), 薬理と治療 22/Suppl3,215-233, Vol. 22, No. Suppl3, p. 215-233, 1994
  • 高分子ヒアルサン酸ナトリウム(NRD101)のウサギにおける器官形成期投与試験(共著), 薬理と治療 22/Suppl3,205-213, Vol. 22, No. Suppl3, p. 205-213, 1994
  • 高分子ヒアルロン酸ナトリウム(NRD101)のラットにおける急性毒性試験(共著), 薬理と治療 22/Suppl3,7-15, Vol. 22, No. Suppl3, p. 7-15, 1994
  • 高分子ヒアルロン酸ナトリウム(NRD101)のラットにおける28日間腹腔内投与による亜急性毒性試験および28日間の回復試験(共著), 薬理と治療 22/Suppl3,31-59, Vol. 22, No. Suppl3, p. 31-59, 1994
  • 高分子ヒアルロン酸ナトリウム(NRD101)のラットにおける器官形成期(共著)投与試験, 薬理と治療 22/Suppl3,185-203, Vol. 22, No. Suppl3, p. 185-203, 1994
  • 高分子ヒアルロン酸ナトリウム(NRD101)のラットにおける器官形成期(共著)投与試験, 薬理と治療, Vol. 22, No. Suppl3, p. 185-203, 1994
  • 高分子ヒアルロン酸ナトリウム(NRD101)のラットにおける28日間腹腔内投与による亜急性毒性試験および28日間の回復試験(共著), 薬理と治療, Vol. 22, No. Suppl3, p. 31-59, 1994
  • 高分子ヒアルロン酸ナトリウム(NRD101)のラットにおける26週間腹腔内投与による慢性毒性試験および5週間の回復試験(共著), 薬理と治療, Vol. 22, No. Suppl3, p. 93-134, 1994
  • 高分子ヒアルロン酸ナトリウム(NRD101)のラットにおける急性毒性試験(共著), 薬理と治療, Vol. 22, No. Suppl3, p. 7-15, 1994
  • 高分子ヒアルサン酸ナトリウム(NRD101)のウサギにおける器官形成期投与試験(共著), 薬理と治療, Vol. 22, No. Suppl3, p. 205-213, 1994
  • 高分子ヒアルロン酸ナトリウム(NRD101)のラットにおける周産期および授乳期投与試験(共著), 薬理と治療, Vol. 22, No. Suppl3, p. 215-233, 1994
  • 高分子ヒアルロン酸ナトリウム(NRD101)のラットにおける妊娠前および妊娠初期投与試験(共著), 薬理と治療, Vol. 22, No. Suppl3, p. 173-184, 1994
  • Fertility Study of High Molecular Weight Sodium Hyaluronate (NRD101) in Rats, Vol. 22, No. Suppl3, p. 173-184, 1994
  • 28-Day Subacute Toxicity Study and 28-Day Recovery Test of High Molecular Weight Sodium Hyaluronate (NRD101) in Rats by Intraperitoneal Administration, Vol. 22, No. Suppl3, p. 31-59, 1994
  • Teratological study of High Molecular Weight Sodium Hyaluronate (NRD101) in Rabbits, Vol. 22, No. Suppl3, p. 205-213, 1994
  • Acute Toxicity Study of High Molecular Weight Sodium Hyaluronate (NRD101) in Rats, Vol. 22, No. Suppl3, p. 7-15, 1994
  • Perinatal and Postnatal Study of High Molecular Weight Sodium Hyalnronate (NRD101) in Rats, Vol. 22, No. Suppl3, p. 215-233, 1994
  • Teratological Study of High Molecular Weight Sodium Hyaluronate (NRD101) in Rats, Japanese Pharmacology & Therapeutics, Vol. 22, No. Suppl3, p. 185-203, 1994
  • 28-Day Subacute Toxicity Study and 28-Day Recovery Test of High Molecular Weight Sodium Hyaluronate (NRD101) in Rats by Intraperitoneal Administration, Japanese Pharmacology & Therapeutics, Vol. 22, No. Suppl3, p. 31-59, 1994
  • Acute Toxicity Study of High Molecular Weight Sodium Hyaluronate (NRD101) in Rats, Japanese Pharmacology & Therapeutics, Vol. 22, No. Suppl3, p. 7-15, 1994
  • Teratological study of High Molecular Weight Sodium Hyaluronate (NRD101) in Rabbits, Japanese Pharmacology & Therapeutics, Vol. 22, No. Suppl3, p. 205-213, 1994
  • Perinatal and Postnatal Study of High Molecular Weight Sodium Hyalnronate (NRD101) in Rats, Japanese Pharmacology & Therapeutics, Vol. 22, No. Suppl3, p. 215-233, 1994
  • Fertility Study of High Molecular Weight Sodium Hyaluronate (NRD101) in Rats, Japanese Pharmacology & Therapeutics, Vol. 22, No. Suppl3, p. 173-184, 1994
  • REDUCTION OF LEAKY LYMPHOCYTE CLONES PRODUCING IMMUNOGLOBULINS AND THYMIC LYMPHOCYTIC-LEUKEMIA BY SELECTIVE INBREEDING OF SCID (SEVERE COMBINED IMMUNODEFICIENCY) MICE, H INOHARA,T NOMURA,T HONGYO,H NAKAJIMA,T KAWAGUCHI,K FUKUDA,K SUTOH,T IWASA,T MATSUNAGA, ACTA OTO-LARYNGOLOGICA, SCANDINAVIAN UNIVERSITY PRESS, Vol. 501, 107-110, p. 107-110, 1993
  • SCIDマウスへのヒト臓器の移植(共著), 血液・腫瘍科 26/6,461-467, Vol. 26, No. 6, p. 461-467, 1993
  • Trandolapril(RU44570)のラットを用いた12か月の経口反復投与毒性試験および3か月間の回復試験(共著), The Journal of Toxicological Sciences 18/Suppl I,37-92, Vol. 37-92, 1993
  • Trandolapril(RU44570)のラットを用いた12か月の経口反復投与毒性試験および3か月間の回復試験(共著), J. Toxicol. Sci., Vol. 18, No. Suppl I, p. 37-92, 1993
  • SCIDマウスへのヒト臓器の移植(共著), 血液・腫瘍科, Vol. 26, No. 6, p. 461-467, 1993
  • Twelve-month oral toxicity study of trandolapril (RU44570) in rats, I. Narama,H. Nakajima,H. Fujishima,W. Kurio,H. Maeda,K. Ozaki,Y. Kumagai,Y. Hiramatsu,E. Takabatake, Journal of Toxicological Sciences, Vol. 18, No. 1, p. 37-92, 1993
  • REDUCTION OF LEAKY LYMPHOCYTE CLONES PRODUCING IMMUNOGLOBULINS AND THYMIC LYMPHOCYTIC-LEUKEMIA BY SELECTIVE INBREEDING OF SCID (SEVERE COMBINED IMMUNODEFICIENCY) MICE, H INOHARA,T NOMURA,T HONGYO,H NAKAJIMA,T KAWAGUCHI,K FUKUDA,K SUTOH,T IWASA,T MATSUNAGA, ACTA OTO-LARYNGOLOGICA, SCANDINAVIAN UNIVERSITY PRESS, Vol. 501, 107-110, p. 107-110, 1993
  • Transplantation of Human Organs into scid Mice, Vol. 26, No. 6, p. 461-467, 1993

Publications

  • Low-Dose-Rate Radiation Effects on Animals and Ecosystem -Long-Term Study on the Fukushima Daiichi Nuclear Power Plant Accident, Manabu Fukumoto,Hiroo Nakajima, Springer Nature, ISBN:9789811382185, 2019/06
  • Physiological, genomic effects in descendant mice after the every generational low dose-rate internal 137Cs radiation exposure., Hiroo Nakajima,Takeshi Todo, Proceedings of the Specialists' Meeting on Effects of the Fukushima-1 Accident on Animals and Planta around the NPP site, 2016/09
  • Mechanism and science for the protecting of living body, Yuji Isegawa,Hiroo Nakajima, Mukogawa Women's University, ISBN:9784907594015, 2015/04
  • Fukushima Nuclear Accident: Global Implications, Long-Term Health Effects and Ecological Consequences, Shizuyo Sutou,Hiroo Nakajima, Nova Science Publishers, ISBN:9781634638203, 2015/03
  • A novel SCID biotechnology for biomedical studies in human., Nomura, T,Nakajima, H,Hongyo,T,Ryo, H,Li,L.Y,Kurooka, M,Baskar, R,Syaifudin, M,Si, X.E,Maeda, M,Kaba, R,Mori, K,Fukudome,Y,Koo,J. Y,Wani,K. M. Y,Kitagawa, Y,Tsuboi, R,Hiramatsu, K,Matsuzuka, F, Radiobiology and Bio-medical Research (Eds. K.P. Mishra), 2004
  • 低線量,低線量率放射線検出のための生物線量計, Institue for Environmental Sciences, 2000
  • Biological concentration of radionuclides in plants and animals after Chernobyl catastrophe., Nakajima, H,Ryo, H,Yamaguchi, Y,Saito, T,Yeliseeva, K.G,Piskunov, E.V,Krupnova, E.V,Voitovich, A.M,Nomura, T, Istitute for Environmental Sciences, 2000
  • Biological concentration of radionuclides in plants and animals after Chernobyl catastrophe, International Symposium on Biological Effects of Low Dose Radiation, 2000
  • Biodosimetry for Detecting Low Dose and Low Dose Rate Radiation, International Symposium on Biological Effects of Low Dose Radiation, 2000

Works

  • 医薬品の厚生省認可に係る安全性(毒性)試験(慢性,亜急性,急性,抗原性,変異原性試験), 1987 - 1990
  • Research for medical drug safety (Chronic, Subacute, Acute, Antigenic, Mutagenic toxicity test), 1987 - 1990
  • チェルノブイリ放射能汚染シミュレーションによる継世代的遺伝毒性と発癌リスク推定, 2010 -
  • 放射線、化学物質の継世代的(遺伝的)影響-マイクロサテライト突然変異誘発と病気, 2010 -
  • 放射線、化学物質の継世代的(遺伝的)影響-マイクロサテライト突然変異誘発と病気, 2009 -
  • チェルノブイリ放射能汚染シミュレーションによる継世代的遺伝毒性と発癌リスク推定, 2009 -
  • チェルノブイリ放射能汚染シミュレーションによる継世代的遺伝毒性と発癌リスク推定, 2008 -
  • 放射線、化学物質の継世代的(遺伝的)影響-マイクロサテライト突然変異誘発と病気, 2008 -
  • 生体DNA二本鎖切断を指標とした微量放射線検出用生物線量計の開発と応用, 2005 -
  • チェルノブイリ放射能汚染地域に棲息する生物体内核種動態と遺伝子損傷, 2005 -
  • 基盤A「核分裂放射能によるヒト臓器・組織障害の発生機構」, 2004 -
  • 生体DNA二本鎖切断を指標とした微量放射線検出用生物線量計の開発と応用, 2004 -
  • チェルノブイリ放射能汚染地域に棲息する生物体内核種動態と遺伝子損傷, 2004 -
  • 情動行動にかかわる遺伝子の同定とその発現機序, 2004 -
  • 生体DNA二本鎖切断を指標とした微量放射線検出用生物線量計の開発と応用, 2003 -
  • 生体DNA二本鎖切断を指標とした微量放射線検出用生物線量計の開発と応用, 2003 -
  • チェルノブイリ核施設崩壊による放射線被曝の子孫への遺伝的影響の研究, 2002 -
  • チェルノブイリ核施設崩壊による放射線被曝の子孫への遺伝的影響の研究, 2002 -
  • ダイオキシンの精子毒性と継世代的影響, 2001 -
  • ダイオキシンの精子毒性と継世代的影響, 2001 -
  • ダイオキシンの精子毒性と継世代的影響, 2000 -
  • ダイオキシンの精子毒性と継世代的影響, 2000 -
  • SCIDマウス由来の培養細胞を用いた微量放射線用生物線量計の開発, 1998 -
  • SCIDマウス由来の培養細胞を用いた微量放射線用生物線量計の開発, 1998 -
  • 放射線影響協会 研究奨励助成金, 1997 -
  • SCIDマウス由来の培養細胞を用いた微量放射線用生物線量計の開発, 1997 -
  • 近紫外線により実験的に誘発されたヒト皮膚がんの特異的遺伝子変異, 1997 -
  • 放射線影響協会 研究奨励助成金, 1997 -
  • SCIDマウス由来の培養細胞を用いた微量放射線用生物線量計の開発, 1997 -
  • 近紫外線により実験的に誘発されたヒト皮膚がんの特異的遺伝子変異, 1997 -
  • 人為的短周期明暗照明リズムの生体への影響, 1996 -
  • 近紫外線によるヒト皮膚がんの実験的誘発と遺伝子変異, 1996 -
  • 人為的短周期明暗照明リズムの生体への影響, 1996 -
  • 近紫外線によるヒト皮膚がんの実験的誘発と遺伝子変異, 1996 -
  • チェルノブィリ事故後のベラルーシにおける微量放射線のヒトおよび生態系におよぼす遺伝的影響の現地調査, 1996 -
  • Field survey in Belarns for the genetic effects of Low dose and low doserate radiation in human, and other organisms after Chelnobyl accident., 1996 -
  • 人為的短周期明暗照明リズムの生体への影響, 1995 -
  • 人為的短周期明暗照明リズムの生体への影響, 1995 -
  • 放射線影響協会 国際研究集会海外派遣助成金, 1994 -
  • 自然環境における日周リズムから離脱した人為日周リズムの生体への影響, 1994 -
  • 放射線影響協会 国際研究集会海外派遣助成金, 1994 -
  • 自然環境における日周リズムから離脱した人為日周リズムの生体への影響, 1994 -
  • 日周リズムの短縮化にともなう腫瘍の増殖促進, 1993 -
  • 日周リズムの短縮化にともなう腫瘍の増殖促進, 1993 -
  • 実験動物の飼育管理, 1980 -
  • Management of Experimental animal room, 1980 -

Awards

  • Best Presentation Elsevier prize, Environmental Mutagen Society of Japan 44th Annual meeting, 2015/11
  • Excellent Poster Award, ICRR2015 15th International Congress of Radiation Research, 2015/05
  • 優秀ポスター賞 第1位, 科学研究費重点領域研究「人間地球系」総括班ポスターコンクール, 1998/10