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Watanabe Mikio

渡邉 幹夫

Graduate School of Medicine Division of Health Sciences, Professor

keyword epigenetics,gene polymorphism,Identical Twin,Internal Medicine,Clinical Immunology,Endocrinology,Preventive Medicine,Clinical Laboratory Science

Education

  • 1993/04 - 1997/03, Osaka University, Graduate School of Medicine, Course of Internal Medicine
  • 1987/04 - 1993/03, Osaka University, Faculty of Medicine, Medical School

Research History

  • 2019/01 - Present, Professor
  • 2019/01 - Present, 大阪大学教授(大学院医学系研究科附属ツインリサーチセンター)(兼任)
  • 2012/04 - 2019/01, Associate Professor of Center for Twin Research, Osaka University Graduate School of Medicine
  • 2012/04 - 2019/01, Associate Professor of Osaka University Graduate School of Medicine
  • 2009/04 - 2012/03, Center of Twin Research, Osaka University, Faculty of Medicine, School of Allied Health Science
  • 2007/04 - 2012/03, Assistant Professor, Osaka University Graduate School of Medicine
  • 2005/10 - 2012/03, 大阪大学学部内講師(大学院医学系研究科保健学専攻)
  • 2003/04 - 2007/03, Assistant Professor of Osaka University Graduate School of Medicine, Course of Health Science
  • 1997/04 - 2003/03, Assistant Professor of Osaka University, Faculty of Medicine, School of Allied Health Science
  • 1998/04 - 2001/03, 大阪大学学内講師(全学共通教育機構)(兼任)

Research Areas

  • Life sciences, Oral medicine (pathology)
  • Life sciences, Internal medicine - General
  • Life sciences, Oral medicine (pathology)
  • Life sciences, Obstetrics and gynecology
  • Life sciences, Internal medicine - General
  • Life sciences, Oral medicine (pathology)
  • Life sciences, Genetics
  • Life sciences, Metabolism and endocrinology
  • Other, Other, Laboratory medicine
  • Life sciences, Healthcare management, medical sociology
  • Life sciences, Immunology
  • Life sciences, Medical biochemistry

Professional Memberships

  • Interrnational Society for Twin Study
  • Asia & Oceania Thyroid Association
  • American Association for Clinical Chemistry
  • 日本臨床検査学教育学会(評議員)(「臨床検査学教育」副編集委員長)
  • The Japan Endocrine Society (Reviewer of Endocrine Journal)
  • American Thyroid Association
  • The Japanese Society for Epigenetics
  • The Japanese Society for Gene Diagnosis and Therapy
  • Japan Society of Internal Medicine
  • Japan Cytometry Society (Certified Cytometrist; CC)
  • Japan Society of Clinical Chemistry (Japan Certified Clinical Chemist; JCCC)
  • The Japan Endocrine Society
  • Japanese Society for Immunology
  • The Japan Society for Clinical Immunology
  • Japanese Society of Internal Medicine
  • Japan Medical Assosication
  • Japanese Society of Laboratory Medicine
  • Japan Thyroid Association
  • 日本臨床検査学教育学会
  • 日本臨床検査学教育学会(評議員)
  • American Thyroid Association
  • The Japanese Society for Epigenetics
  • 日本臨床化学会近畿支部
  • 日本医学会
  • 健康食品管理士会(認定健康食品管理士)
  • Japan Cytometry Society (Certified Cytometrist; CC)
  • Japan Society of Clinical Chemistry (Japan Certified Clinical Chemist; JCCC)
  • Japan Thyroid Association
  • The Japanese Society for Gene Diagnosis and Therapy
  • Japanese Society for Immunology
  • 日本内分泌学会
  • 日本内科学会
  • 健康食品管理士会
  • 日本サイトメトリー学会
  • 日本臨床化学会
  • 日本臨床免疫学会
  • 日本甲状腺学会
  • 日本臨床検査医学会

Papers

  • Relationship between Nutrient Intake and Human Gut Microbiota in Monozygotic Twins, Natsuko Matsumoto,Jonguk Park,Rie Tomizawa,Hitoshi Kawashima,Koji Hosomi,Kenji Mizuguchi,Chika Honda,Ritsuko Ozaki,Yoshinori Iwatani,Mikio Watanabe,Jun Kunisawa, Medicina, MDPI AG, Vol. 57, No. 3, p. 275-275, 2021/03/16
  • Genetic and environmental variation in educational attainment: an individual-based analysis of 28 twin cohorts, Karri Silventoinen,Aline Jelenkovic,Reijo Sund,Antti Latvala,Chika Honda,Fujio Inui,Rie Tomizawa,Mikio Watanabe,Norio Sakai,Esther Rebato,Andreas Busjahn,Jessica Tyler,John L. Hopper,Juan R. Ordoñana,Juan F. Sánchez-Romera,Lucia Colodro-Conde,Lucas Calais-Ferreira,Vinicius C. Oliveira,Paulo H. Ferreira,Emanuela Medda,Lorenza Nisticò,Virgilia Toccaceli,Catherine A. Derom,Robert F. Vlietinck,Ruth J. F. Loos,Sisira H. Siribaddana,Matthew Hotopf,Athula Sumathipala,Fruhling Rijsdijk,Glen E. Duncan,Dedra Buchwald,Per Tynelius,Finn Rasmussen,Qihua Tan,Dongfeng Zhang,Zengchang Pang,Patrik K. E. Magnusson,Nancy L. Pedersen,Anna K. Dahl Aslan,Amie E. Hwang,Thomas M. Mack,Robert F. Krueger,Matt McGue,Shandell Pahlen,Ingunn Brandt,Thomas S. Nilsen,Jennifer R. Harris,Nicholas G. Martin,Sarah E. Medland,Grant W. Montgomery,Gonneke Willemsen,Meike Bartels,Catharina E. M. van Beijsterveldt,Carol E. Franz,William S. Kremen,Michael J. Lyons,Judy L. Silberg,Hermine H. Maes,Christian Kandler,Tracy L. Nelson,Keith E. Whitfield,Robin P. Corley,Brooke M. Huibregtse,Margaret Gatz,David A. Butler,Adam D. Tarnoki,David L. Tarnoki,Hang A. Park,Jooyeon Lee,Soo Ji Lee,Joohon Sung,Yoshie Yokoyama,Thorkild I. A. Sørensen,Dorret I. Boomsma,Jaakko Kaprio, Scientific Reports, Springer Science and Business Media LLC, Vol. 10, No. 1, 2020/12
  • Up-To-Date Laboratory Tests of Autoimmune diseases, Mikio WATANABE, Rinsho-Byori, Vol. 68, No. 12, p. 989-993, 2020/12
  • Heritability and Environmental Correlation of Phase Angle with Anthropometric Measurements: A Twin Study, Daisuke Matsumoto,Fujio Inui,Chika Honda,Rie Tomizawa,Mikio Watanabe,Karri Silventoinen,Norio Sakai, International Journal of Environmental Research and Public Health, MDPI AG, Vol. 17, No. 21, p. 7810-7810, 2020/10/26
  • Combination of multicolor flow cytometry for circulating lymphoma cells and tests for the RHOAG17V and IDH2R172 hot-spot mutations in plasma cell-free DNA as liquid biopsy for the diagnosis of angioimmunoblastic T-cell lymphoma, Masahiko Hayashida,Fumiyo Maekawa,Yoshinari Chagi,Futoshi Iioka,Yoichiro Kobashi,Mikio Watanabe,Hitoshi Ohno, Leukemia & Lymphoma, Informa UK Limited, Vol. 61, No. 10, p. 2389-2398, 2020/08/23
  • Increases of CD80 and CD86 expression on peripheral blood cells and their gene polymorphisms in autoimmune thyroid disease., Watanabe, A,Inoue, N,Watanabe, M,Yamamoto, M,Ozaki, H,Hidaka, Y,Iwatani, Y, Immunological Investigation, Vol. 49, No. 1-2, p. 191-203, 2020/02
  • Association of CD58 polymorphisms and its protein expression with the development and prognosis of autoimmune thyroid diseases., Yamamoto, M,Watanabe, M,Inoue, N,Watanabe, A,Ozaki, H,Ohsaki, M,Yidaka, Y,Iwatani, Y, Immunological Investigations, Vol. 49, No. 1-2, p. 106-119, 2020/02
  • Gene polymorphisms of <i>VEGF</i> and <i>VEGFR2</i> are associated with the severity of Hashimoto’s disease and the intractability of Graves’ disease, respectively, Mami Okamoto,Mikio Watanabe,Naoya Inoue,Kazane Ogawa,Yoh Hidaka,Yoshinori Iwatani, Endocrine Journal, Japan Endocrine Society, Vol. 67, No. 5, p. 545-559, 2020
  • Opinion "Foster a sense of mission", Watanabe, Mikio, Japanese Journal of Clinical Chemistry, Vol. 49, No. 1, p. 51-51, 2020/01
  • In tube immunocytochemistry for fluorescence-activated cell sorting that prevents RNA degradation in sorted cells., Fukano, H,Takano, T,Fujimoto, Y,Nakatani, R,Watanabe, M,Hidaka, Y,Shimomura, I, Biotech Histochem, Vol. 95, No. 1, p. 1-7, 2020/01
  • Update on Osaka University Twin Registry: An Overview of Multidisciplinary Research Resources and Biobank at Osaka University Center for Twin Research, Honda, C,Watanabe, M,Tomizawa, R,Osaka Twin,Research Group,Sakai, N, Twin Res Hum Genet, p. 1-5, 2019/12
  • Enhanced processivity of Dnmt1 by mono-ubiquitinated histone H3, Mishima, Y,Brueckner, L,Takahashi, S,Kawakami, T,Otani, J,Shinohara, A,Takeshita, K,Garvilles, R,Watanabe, M,Sakai, N,Takeshima, H,Nachtegael, C,Nishiyama, A,Nakanishi, M,Arita, K,Nakashima, K,Hojo, H,Suetake, I, Genes to Cells, 2019/11
  • Association of IL6 gene methylation in peripheral blood cells with the development and prognosis of autoimmune thyroid diseases, Hirai, N,Watanabe, M,Inoue, N,Kishonita, R,Ohtani, H,Hidaka, Y,Iwatani, Y, Autoimmunity, Vol. 52, No. 7-8, p. 191-203, 2019/11
  • Association of IFNG gene methylation in peripheral blood cells with the development and prognosis of autoimmune thyroid disease, Hashimoto, H,Watanabe, M,Inoue, N,Hirai, N,Haga, E,Kinoshita, R,Hidaka, Y,Iwatani, Y, Cytokine, Vol. 123, p. 154770-154770, 2019/10
  • The CODATwins Project: The Current Status and Recent Findings of COllaborative Project of Development of Anthropometrical Measures in Twins., Silventoinen K, Twin Res Hum Genet, 2019/08
  • Fault classification with discriminant analysis during sit-to-stand movement assisted by a nursing care robot, Tianyi Wang,Hieyong Jeong,Mikio Watanabe,Yoshinori Iwatani,Yuko Ohno, Mechanical Systems and Signal Processing, Vol. 113, p. 90-101, 2018/12
  • Polymorphisms in Th17-related genes and the pathogenesis of autoimmune thyroid disease, Kunisato, T,Watanabe, M,Inoue, N,Okada, A,Nanba, T,Kobayashi, W,Inoue, Y,Katsumata, Y,Omori, N,Nobuhara, T,Takemura, K,Hidaka, Y,Iwatani, Y, Autoimmunity, Vol. 51, No. 7, p. 360-369, 2018/11
  • Association of the polymorphisms in Th2 chemotaxis-related genes with the development and prognosis of autoimmune thyroid diseases, Omori, N,Watanabe, M,Inoue, N,Taniguchi, J,Hidaka, Y,Iwatani, Y, Endocrine J, Vol. 65, No. 8, p. 815-826, 2018/08
  • Functional Polymorphisms of the Type 1 and Type 2 Iodothyronine Deiodinase Genes in Autoimmune Thyroid Diseases, Naoya Inoue,Mikio Watanabe,Yuka Katsumata,Naoko Ishido,Yoh Hidaka,Yoshinori Iwatani, Immunological Investigations, Taylor and Francis Ltd, Vol. 47, No. 5, p. 534-542, 2018/07/04
  • Association of current and former smoking with body mass index: a study of smoking discordant twin pairs from 21 twin cohorts, Piirtola, N,Jelenkovic, A,Latvala, A,Sund. R,Honda, C,Inui, F,Watanabe, M,Tomizawa, R,Iwatani, Y, PLOS ONE, Vol. 17, No. 7, 2018/07
  • Mean platelet component and mean platelet volume are the useful screening markers of myelodysplastic syndrome., Masutani, R,Ikemoto, T,Maki, A,Tanada, H,Iwatani, Y,Watanabe, M,Takubo, T,Okada, Y, Health Science Reports, Vol. 1, No. 5, 2018/05
  • Methylation levels of the TNFA gene are different between Graves’ and Hashimoto’s diseases and influenced by the TNFA polymorphism, Emi Morita,Mikio Watanabe,Naoya Inoue,Hidemi Hashimoto,Emi Haga,Yoh Hidaka,Yoshinori Iwatani, Autoimmunity, Taylor and Francis Ltd, Vol. 51, No. 3, p. 118-125, 2018/04/03
  • 論文紹介(gamma-delta T cells enhance B cells for antibody production in Hashimoto's thyroiditis, and Retinoic acid induces apoptosis for the gamma-delta T cell), Vol. 9, No. 1, p. 86-86, 2018/04
  • Twin study is an essential research method to clarify the crucial genetic and environmental factors for human phenotypes, Honda, C,Watanabe, M,Iwatani, Y, Gene & Medicine MOOK, メディカルドゥ, No. 33, p. 49-51, 2018/04
  • Polymorphisms and expression of genes encoding Argonautes 1 and 2 in autoimmune thyroid diseases, Ena Tokiyoshi,Mikio Watanabe,Naoya Inoue,Yoh Hidaka,Yoshinori Iwatani, Autoimmunity, Taylor and Francis Ltd, Vol. 51, No. 1, p. 35-42, 2018/01/02
  • Frequency-specific genetic influence on inferior parietal lobule activation commonly observed during action observation and execution, Araki T,Onishi M,Yanagisawa T,Hirata M,Watanabe Y,Ogata S,Hayakawa K,Honda C,Watanabe M,Iwatani Y,Yorifuji S, Scientific Reports, NATURE PUBLISHING GROUP, Vol. 7, No. 1, 2017/12
  • Genotype-based epigenetic differences in monozygotic twins discordant for positive anti-thyroglobulin autoantibodies, Watanabe, M,Takenaka, Y,Honda, C,Osaka Twin,research Group,Iwatani, Y, Thyroid, Vol. 28, No. 1, p. 110-123, 2017/12
  • 認定試験と巡礼, Vol. 42, No. 4, p. 200-200, 2017/12
  • Education in twins and their parents across birth cohorts over 100 years: an individual-level pooled analysis of 42 twin cohorts., Silventoinen,K. Jelenkovic, A,Latvala, A,Sund, R,Yokoyama, Y,Ullemar, V,Almqvist, C,Derom, C.A,Vlietinck, R.F,Loos, R.JF,Kandler, C,Honda, C,Inui, F,Iwatani, Y,Watanabe, M, Twin Research and Humman Genetics, CAMBRIDGE UNIV PRESS, Vol. 20, No. 5, p. 395-405, 2017/11
  • The polymorphisms in the thyroid peroxidase gene were associated with the development of autoimmune thyroid disease and the serum levels of TPOAb., Tomari, S,Watanabe, M,Inoue, N,Mizuma, T,Yamanaka, C,Hidaka, Y,Iwatani, Y, Endocrine Journal, JAPAN ENDOCRINE SOC, Vol. 64, No. 10, p. 1025-1032, 2017/10
  • RFTS-dependent negative regulation of Dnmt1 by nucleosome structure and histone tails, Yuichi Mishima,Laura Brueckner,Saori Takahashi,Toru Kawakami,Kyohei Arita,Shota Oka,Junji Otani,Hironobu Hojo,Masahiro Shirakawa,Akira Shinohara,Mikio Watanabe,Isao Suetake, FEBS JOURNAL, WILEY, Vol. 284, No. 20, p. 3455-3469, 2017/10
  • Thyroid hormone and autoimmune diseases, Watanabe, M, Journal of the Japan Thyroid Association, Vol. 8, No. 2, p. 147-155, 2017/10
  • Thyroid hormone and autoimmune diseases, Watanabe, M, Journal of the Japan Thyroid Association, Vol. 8, No. 2, p. 161-169, 2017/10
  • Association of the polymorphisms in the gene encoding thyroglobulin with the development and prognosis of autoimmune thyroid disease, Tomoyo Mizuma,Mikio Watanabe,Naoya Inoue,Yuya Arakawa,Saki Tomari,Yoh Hidaka,Yoshinori Iwatani, Autoimmunity, TAYLOR & FRANCIS LTD, Vol. 50, No. 6, p. 386-392, 2017/09
  • Association of IL-10-Regulating MicroRNAs in Peripheral Blood Mononuclear Cells with the Pathogenesis of Autoimmune Thyroid Disease., Takuse, Y,Watanabe, M,Inoue, N,Ozaki, R,Otsu, H,Saeki, M,Katsumata, Y,Hidaka, Y,Iwatani, Y, Immunological Investigation, TAYLOR & FRANCIS INC, Vol. 46, No. 6, p. 590-602, 2017/08
  • Functional polymorphisms affecting Th1 differentiation are associated with the severity of autoimmune thyroid diseases, Inoue, N,Watanabe, M,Nakaguchi, A,Ueda, A,Kawaguchi, H,Hidaka, Y,Iwatani, Y, Endocrine Journal, JAPAN ENDOCRINE SOC, Vol. 64, No. 7, p. 695-703, 2017/07
  • Differences in genetic and environmental variation in adult body mass index by sex, age, time period, and region: an individual-based pooled analysis of 40 twin cohorts, Karri Silventoinen,Aline Jelenkovic,Reijo Sund,Yoshie Yokoyama,Yoon-Mi Hur,Wendy Cozen,Amie E. Hwang,Thomas M. Mack,Chika Honda,Fujio Inui,Yoshinori Iwatani,Mikio Watanabe,Rie Tomizawa,Kirsi H. Pietilainen,Aila Rissanen,Sisira H. Siribaddana,Matthew Hotopf,Athula Sumathipala,Fruhling Rijsdijk,Qihua Tan,Dongfeng Zhang,Zengchang Pang,Maarit Piirtola,Sari Aaltonen,Sevgi Y. Oncel,Fazil Aliev,Esther Rebato,Jacob B. Hjelmborg,Kaare Christensen,Axel Skytthe,Kirsten O. Kyvik,Judy L. Silberg,Lindon J. Eaves,Tessa L. Cutler,Juan R. Ordonana,Juan F. Sanchez-Romera,Lucia Colodro-Conde,Yun-Mi Song,Sarah Yang,Kayoung Lee,Carol E. Franz,William S. Kremen,Michael J. Lyons,Andreas Busjahn,Tracy L. Nelson,Keith E. Whitfield,Christian Kandler,Kerry L. Jang,Margaret Gatz,David A. Butler,Maria A. Stazi,Corrado Fagnani,Cristina D'Ippolito,Glen E. Duncan,Dedra Buchwald,Nicholas G. Martin,Sarah E. Medland,Grant W. Montgomery,Hoe-Uk Jeong,Gary E. Swan,Ruth Krasnow,Patrik Ke Magnusson,Nancy L. Pedersen,Anna K. Dahl Aslan,Tom A. McAdams,Thalia C. Eley,Alice M. Gregory,Per Tynelius,Laura A. Baker,Catherine Tuvblad,Gombojav Bayasgalan,Danshiitsoodol Narandalai,Timothy D. Spector,Massimo Mangino,Genevieve Lachance,S. Alexandra Burt,Kelly L. Klump,Jennifer R. Harris,Ingunn Brandt,Thomas S. Nilsen,Robert F. Krueger,Matt Mcgue,Shandell Pahlen,Robin P. Corley,Brooke M. Huibregtse,Meike Bartels,Catharina E. M. van Beijsterveldt,Gonneke Willemsen,Jack H. Goldberg,Finn Rasmussen,Adam D. Tarnoki,David L. Tarnoki,Catherine A. Derom,Robert F. Vlietinck,Ruth J. F. Loos,John L. Hopper,Joohon Sung,Hermine H. Maes,Eric Turkheimer,Dorret I. Boomsma,Thorkild I. A. Sorensen,Jaakko Kaprio, The American Journal of Clinical Nutrition, AMER SOC NUTRITION-ASN, Vol. 106, No. 2, p. 457-466, 2017/07
  • Polymorphisms in and expression of Toll-like receptors in autoimmune thyroid diseases, Naoya Inoue,Yuka Katsumata,Mikio Watanabe,Naoko Ishido,Yu Manabe,Ayano Watanabe,Ryota Masutani,Yoh Hidaka,Yoshinori Iwatani, Autoimmunity, TAYLOR & FRANCIS LTD, Vol. 50, No. 3, p. 182-191, 2017/06
  • The IL15 +96522 A>T functional polymorphism is related to the differentiation of Th17 cells and the severity of Hashimoto's disease, Yuya Arakawa,Mikio Watanabe,Kazuya Takemura,Naoya Inoue,Yoh hidaka,Yoshinori Iwatani, International Journal of Immunogenetics, WILEY, Vol. 44, No. 2, p. 41-50, 2017/05
  • Intraindividual variation of microRNA expression levels in plasma and peripheral blood mononuclear cells and the associations of these levels with the pathogenesis of autoimmune thyroid diseases, Hiroshi Otsu,Mikio Watanabe,Naoya Inoue,Ryota Masutani,Yoshinori Iwatani, Clinical Chemistry and Laboratory Medicine, Walter de Gruyter GmbH, Vol. 55, No. 5, p. 626-635, 2017/05/01
  • TSHR gene polymorphisms in the enhancer regions are most strongly associated with the development of Graves' disease, especially intractable disease, and with that of Hashimoto's disease, Asami Fujii,Naoya Inoue,Mikio Watanabe,Chisa Kawakami,Yoh Hidaka,Yoshihide Hayashizaki,Yoshinori Iwatani, Thyroid, MARY ANN LIEBERT, INC, Vol. 27, No. 1, p. 111-119, 2017/01
  • Optimization of recovery and analysis of RNA in sorted cells in mRNA quantification after fluorescence-activated cell sorting., Maeda, T,Date, A,Watanabe, M,Hidaka, Y,Iwatani, Y,Takano, T, Ann Clin Lab Sci, Vol. 46, No. 6, p. 435-441, 2016/12
  • Genetic and environmental influences on adult human height across birth cohorts from 1886 to 1994, Jelenkovic, A,Hur, Y,Sund, R, eLife, ELIFE SCIENCES PUBLICATIONS LTD, Vol. 5, 2016/12
  • DICER and DROSHA gene expression and polymorphisms in autoimmune thyroid diseases, Minori Saeki,Mikio Watanabe,Naoya Inoue,Ena Tokiyoshi,Yukina Takuse,Yuya Arakawa,Yoh Hidaka,Yoshinori Iwatani, Autoimmunity, TAYLOR & FRANCIS LTD, Vol. 49, No. 8, p. 514-522, 2016/12
  • Language-related cerebral oscillatory changes are influenced equally by genetic and environmental factors, Toshihiko Araki,Osaka Twin Research Group,Masayuki Hirata,Takufumi Yanagisawa,Hisato Sugata,Mai Onishi,Yoshiyuki Watanabe,Soshiro Ogata,Chika Honda,Kazuo Hayakawa,Shiro Yorifuji,Yoshinori Iwatani,Norio Sakai,Kei Kamide,Shinji Kihara,Kiyoko Makimoto,Hiroko Watanabe,Jun Hatazawa,Masanori Takahashi,Mikio Watanabe,Chika Honda,Rie Tomizawa, NeuroImage, Academic Press Inc., Vol. 142, p. 241-247, 2016/11/15
  • Optimization of Recovery and Analysis of RNA in Sorted Cells in mRNA Quantification After Fluorescence-activated Cell Sorting, Tomoko Maeda,Arisa Date,Mikio Watanabe,Yoh Hidaka,Yoshinori Iwatani,Toru Takano, ANNALS OF CLINICAL AND LABORATORY SCIENCE, ASSOC CLINICAL SCIENTISTS, Vol. 46, No. 6, p. 571-577, 2016/11
  • Involvement of genes encoding apoptosis regulatory factors (FAS, FASL, TRAIL, BCL2, TNFR1 and TNFR2) in the pathogenesis of autoimmune thyroid diseases, Inoue, N,Watanabe, M,Ishido, N,Kodu, A,Maruoka, H,Katsumata, Y,Hidaka, Y,Iwatani, Y, Hum Immunol, ELSEVIER SCIENCE INC, Vol. 77, No. 10, p. 944-951, 2016/10
  • Within-pair differences of DNA methylation levels between monozygotic twins are different between male and female pairs., Watanabe, M,Honda, C,The Osaka Twin,Research Group,Iwatani, Y, BMC Medical Genomics, Vol. 9, p. 55-63, 2016/09
  • Within-pair differences of DNA methylation levels between monozygotic twins are different between male and female pairs., Watanabe, M,Honda, C,The Osaka Twin,Research Group,Iwatani, Y, BMC Medical Genomics, BIOMED CENTRAL LTD, Vol. 9, p. 55-63, 2016/09
  • 考える臨床検査―スクリーニング検査で異常値をみたら?―, Vol. 8, No. 2, p. 229-229, 2016/08
  • Association of the polymorphisms of chemokine genes (IL8, RANTES, MIG, IP10, MCP1 and IL16) with the pathogenesis of autoimmune thyroid diseases, Maiko Akahane,Mikio Watanabe,Naoya Inoue,Yumi Miyahara,Yuya Arakawa,Yuka Inoue,Yuka Katsumata,Yoh Hidaka,Yoshinori Iwatani, Autoimmunity, TAYLOR & FRANCIS LTD, Vol. 49, No. 5, p. 312-319, 2016/08
  • Association between functional SIRT1 polymorphisms and the clinical characteristics of patients with autoimmune thyroid disease, Mika Sarumaru,Mikio Watanabe,Naoya Inoue,Yuko Hisamoto,Emi Morita,Yuya Arakawa,Yoh Hidaka,Yoshinori Iwatani, Autoimmunity, TAYLOR & FRANCIS LTD, Vol. 49, No. 5, p. 329-337, 2016/08
  • 考える臨床検査―スクリーニング検査で異常値をみたら?―, Vol. 8, No. 2, p. 229-229, 2016/08
  • Association between functional SIRT1 polymorphisms and the clinical characteristics of patients with autoimmune thyroid disease, Mika Sarumaru,Mikio Watanabe,Naoya Inoue,Yuko Hisamoto,Emi Morita,Yuya Arakawa,Yoh Hidaka,Yoshinori Iwatani, Autoimmunity, TAYLOR & FRANCIS LTD, Vol. 49, No. 5, p. 329-337, 2016/08
  • Association of the polymorphisms of chemokine genes (IL8, RANTES, MIG, IP10, MCP1 and IL16) with the pathogenesis of autoimmune thyroid diseases, Maiko Akahane,Mikio Watanabe,Naoya Inoue,Yumi Miyahara,Yuya Arakawa,Yuka Inoue,Yuka Katsumata,Yoh Hidaka,Yoshinori Iwatani, Autoimmunity, TAYLOR & FRANCIS LTD, Vol. 49, No. 5, p. 312-319, 2016/08
  • Increases of microRNA let-7e in peripheral blood mononuclear cells in Hashimoto's disease. Endocrin J (in press) Sarumaru, M., Watanab, Kagawa, T,Watanabe, M,Inoue, N,Otsu, H,Saeki, M,Katsumata, Y,Takuse, Y,Iwatani, Y, Endocrine Journal, JAPAN ENDOCRINE SOC, Vol. 63, No. 4, p. 375-380, 2016/04
  • Association of polymorphisms in the ICOS and ICOSL genes with the pathogenesis of autoimmune thyroid diseases, Yoshie, N,Watanabe, M,Inoue, N,Kawaguchi, H,Hidaka, Y,Iwatani, Y, Endocrine Journal, JAPAN ENDOCRINE SOC, Vol. 63, No. 1, p. 61-68, 2016/01
  • Zygosity Differences in Height and Body Mass Index of Twins From Infancy to Old Age: A Study of the CODATwins Project., Jelenkovic A,Yokoyama Y,Sund R,Honda C,Bogl LH,Aaltonen S,Ji F,Ning F,Pang Z,Ordoñana JR,Sánchez-Romera JF,Colodro-Conde L,Burt SA,Klump KL,Medland SE,Montgomery GW,Kandler C,McAdams TA,Eley TC,Gregory AM,Saudino KJ,Dubois L,Boivin M,Tarnoki AD,Tarnoki DL,Haworth CM,Plomin R,Öncel SY,Aliev F,Stazi MA,Fagnani C,D'Ippolito C,Craig JM,Saffery R,Siribaddana SH,Hotopf M,Sumathipala A,Rijsdijk F,Spector T,Mangino M,Lachance G,Gatz M,Butler DA,Bayasgalan G,Narandalai D,Freitas DL,Maia JA,Harden KP,Tucker-Drob EM,Kim B,Chong Y,Hong C,Shin HJ,Christensen K,Skytthe A,Kyvik KO,Derom CA,Vlietinck RF,Loos RJ,Cozen W,Hwang AE,Mack TM,He M,Ding X,Chang B,Silberg JL,Eaves LJ,Maes HH,Cutler TL,Hopper JL,Aujard K,Magnusson PK, Twin Res Hum Genet, CAMBRIDGE UNIV PRESS, Vol. 18, No. 5, p. 557-570, 2015/10
  • The CODATwins Project: The Cohort Description of Collaborative Project of Development of Anthropometrical Measures in Twins to Study Macro-Environmental Variation in Genetic and Environmental Effects on Anthropometric Traits, Karri Silventoinen,Aline Jelenkovic,Reijo Sund,Chika Honda,Sari Aaltonen,Yoshie Yokoyama,Adam D. Tarnoki,David L. Tarnoki,Feng Ning,Fuling Ji,Zengchang Pang,Juan R. Ordonana,Juan F. Sanchez-Romera,Lucia Colodro-Conde,S. Alexandra Burt,Kelly L. Klump,Sarah E. Medland,Grant W. Montgomery,Christian Kandler,Tom A. McAdams,Thalia C. Eley,Alice M. Gregory,Kimberly J. Saudino,Lise Dubois,Michel Boivin,Claire M. A. Haworth,Robert Plomin,Sevgi Y. Oncel,Fazil Aliev,Maria A. Stazi,Corrado Fagnani,Cristina D'Ippolito,Jeffrey M. Craig,Richard Saffery,Sisira H. Siribaddana,Matthew Hotopf,Athula Sumathipala,Timothy Spector,Massimo Mangino,Genevieve Lachance,Margaret Gatz,David A. Butler,Gombojav Bayasgalan,Danshiitsoodol Narandalai,Duarte L. Freitas,Jose Antonio Maia,K. Paige Harden,Elliot M. Tucker-Drob,Kaare Christensen,Axel Skytthe,Kirsten O. Kyvik,Changhee Hong,Youngsook Chong,Catherine A. Derom,Robert F. Vlietinck,Ruth J. F. Loos,Wendy Cozen,Amie E. Hwang,Thomas M. Mack,Mingguang He,Xiaohu Ding,Billy Chang,Judy L. Silberg,Lindon J. Eaves,Hermine H. Maes,Tessa L. Cutler,John L. Hopper,Kelly Aujard,Patrik K. E. Magnusson,Nancy L. Pedersen,Anna K. Dahl Aslan,Yun-Mi Song,Sarah Yang,Kayoung Lee,Laura A. Baker,Catherine Tuvblad,Morten Bjerregaard-Andersen,Henning Beck-Nielsen,Morten Sodemann,Kauko Heikkila,Qihua Tan,Dongfeng Zhang,Gary E. Swan,Ruth Krasnow,Kerry L. Jang,Ariel Knafo-Noam,David Mankuta,Lior Abramson,Paul Lichtenstein,Robert F. Krueger,Matt Mcgue,Shandell Pahlen,Per Tynelius,Glen E. Duncan,Dedra Buchwald,Robin P. Corley,Brooke M. Huibregtse,Tracy L. Nelson,Keith E. Whitfield,Carol E. Franz,William S. Kremen,Michael J. Lyons,Syuichi Ooki,Ingunn Brandt,Thomas Sevenius Nilsen,Fujio Inui,Mikio Watanabe,Meike Bartels,Toos C. E. M. van Beijsterveldt,Jane Wardle,Clare H. Llewellyn,Abigail Fisher,Esther Rebato,Nicholas G. Martin,Yoshinori Iwatani,Kazuo Hayakawa,Finn Rasmussen,Joohon Sung,Jennifer R. Harris,Gonneke Willemsen,Andreas Busjahn,Jack H. Goldberg,Dorret I. Boomsma,Yoon-Mi Hur,Thorkild I. A. Sorensen,Jaakko Kaprio, TWIN RESEARCH AND HUMAN GENETICS, CAMBRIDGE UNIV PRESS, Vol. 18, No. 4, p. 348-360, 2015/08
  • The CODATwins Project: The Cohort Description of Collaborative Project of Development of Anthropometrical Measures in Twins to Study Macro-Environmental Variation in Genetic and Environmental Effects on Anthropometric Traits., Silventoinen K,Jelenkovic A,Sund R,Honda C,Aaltonen S,Yokoyama Y,Tarnoki AD,Tarnoki DL,Ning F,Ji F,Pang Z,Ordoñana JR,Sánchez-Romera JF,Colodro-Conde L,Burt SA,Klump KL,Medland SE,Montgomery GW,Kandler C,McAdams TA,Eley TC,Gregory AM,Saudino KJ,Dubois L,Boivin M,Haworth CM,Plomin R,Öncel SY,Aliev F,Stazi MA,Fagnani C,D'Ippolito C,Craig JM,Saffery R,Siribaddana SH,Hotopf M,Sumathipala A,Spector T,Mangino M,Lachance G,Gatz M,Butler DA,Bayasgalan G,Narandalai D,Freitas DL,Maia JA,Harden KP,Tucker-Drob EM,Christensen K,Skytthe A,Kyvik KO,Hong C,Chong Y,Derom CA,Vlietinck RF,Loos RJ,Cozen W,Hwang AE,Mack TM,He M,Ding X,Chang B,Silberg JL,Eaves LJ,Maes HH,Cutler TL,Hopper JL,Aujard K,Magnusson PK,Pedersen NL,Aslan AK, Twin Res Hum Genet, Vol. 27, No. 4, p. 1-13, 2015/04
  • Association between functional polymorphisms in the toll-like receptor 4 (TLR4) gene and HD severity., Naoya Inoue,Mikio Watanabe,Yuka Katsumata,Naoko Ishido,Yoh Hidaka,Yoshinori Iwatani, Tissue Antigens, WILEY-BLACKWELL, Vol. 85, No. 3, p. 209-211, 2015/03
  • The Relationship between Skewed X Chromosome Inactivation and the Prognosis of Graves' and Hashimoto's Diseases, Naoko Ishido,Naoya Inoue,Mikio Watanabe,Yoh Hidaka,Yoshinori Iwatani, Thyroid, MARY ANN LIEBERT, INC, Vol. 25, No. 2, p. 256-261, 2015/02
  • Expression Analysis of Stemness Genes in a Rat Thyroid Cell Line FRTL5., Asami Shimasue,Noriko Yamakawa,Mikio Watanabe,Yoh Hidaka,Yoshinori Iwatani,Toru Takano, Exp Clin Endocrinol Diabetes, JOHANN AMBROSIUS BARTH VERLAG MEDIZINVERLAGE HEIDELBERG GMBH, Vol. 123, No. 1, p. 48-54, 2015/01
  • The functional polymorphisms of VDR, GC and CYP2R1 are involved in the pathogenesis of autoimmune thyroid diseases, Naoya Inoue,Mikio Watanabe,Naoko Ishido,Yuka Katsumata,Tomoya Kagawa,Yoh Hidaka,Yoshinori Iwatani, Clinical and Experimental Immunology, WILEY-BLACKWELL, Vol. 178, No. 2, p. 262-269, 2014/11
  • Associations of single nucleotide polymorphisms in precursor-microRNA (miR)-125a and the expression of mature miR-125a with the development and prognosis of autoimmune thyroid diseases, Y. Inoue,M. Watanabe,N. Inoue,T. Kagawa,S. Shibutani,H. Otsu,M. Saeki,Y. Takuse,Y. Hidaka,Y. Iwatani, CLINICAL AND EXPERIMENTAL IMMUNOLOGY, WILEY-BLACKWELL, Vol. 178, No. 2, p. 229-235, 2014/11
  • The functional polymorphisms of VDR, GC and CYP2R1 are involved in the pathogenesis of autoimmune thyroid diseases, Naoya Inoue,Mikio Watanabe,Naoko Ishido,Yuka Katsumata,Tomoya Kagawa,Yoh Hidaka,Yoshinori Iwatani, Clinical and Experimental Immunology, WILEY-BLACKWELL, Vol. 178, No. 2, p. 262-269, 2014/11
  • Associations of single nucleotide polymorphisms in pri-miR-125a and the expression of mature miR-125a with the development and prognosis of autoimmune thyroid diseases., Yuka Inoue,Mikio Watanabe,Naoya Inoue,Tomoya Kagawa,Sayaka Shibutani,Hiroshi Otsu,Minori Saeki,Yukina Takuse,Yoh Hidaka,Yoshinori Iwatani, Clinical and Experimental Immunology, WILEY-BLACKWELL, Vol. 178, No. 2, p. 229-235, 2014/11
  • An improved protocol for mRNA quantification after fluorescence-activated cell sorting with an increased signal to noise ratio in flow cytometry., Arisa Date,Tokoko Maeda,Mikio Watanabe,Yoh Hidaka,Yoshinori Iwatani,Toru Takano, Molecular biotechnology, HUMANA PRESS INC, Vol. 56, No. 7, p. 591-598, 2014/07
  • Genome-wide association study and its application to thyroid diseases, Mikio Watanabe, Journal of the Japan Thyroid Association, Vol. 5, No. 1, p. 9-13, 2014/04
  • The GG genotype of the -1125G/T polymorphism in the EPO gene protects against the development of Graves' disease, Naoya Inoue,Mikio Watanabe,Takayuki Nobuhara,Yoh Hidaka,Yoshinori Iwatani, Immunology Letters, ELSEVIER SCIENCE BV, Vol. 56, No. 1-2, p. 156-158, 2013/12
  • Different genotypes of a functional polymorphism of the TSHR gene are associated with the development and severity of Graves' and Hashimoto's diseases, N. Inoue,M. Watanabe,Y. Katsumata,Y. Hidaka,Y. Iwatani, Tissue Antigens, Vol. 82, No. 4, p. 288-290, 2013/10
  • IL-10 -592A/C polymorphism is associated with severity of Hashimoto's disease, Naoya Inoue,Mikio Watanabe,Megumi Wada,Mami morita,Yoh Hidaka,Yoshinori Iwatani, Cytokine, ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD, Vol. 64, No. 1, p. 370-374, 2013/07
  • Preparation of thyroid follicular cells for mRNA quantification after fluorescence-activated cell sorting, Chisa Matsumoto,Mitsuru Ito,Hiroya Yamada,Hiroshi Yoshida,Mikio Watanabe,Yoh Hidaka,Yoshinori Iwatani,Akira Miyauch,Toru Takano, SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION, INFORMA HEALTHCARE, Vol. 73, No. 3, p. 245-252, 2013/04
  • The association between a functional polymorphism in the CD24 gene and the development of autoimmune thyroid diseases, Inoue, N,Watanabe, M,Hayashi F,Hidaka, Y,Iwatani, Y, Tissue Antigen, WILEY-BLACKWELL, Vol. 81, No. 3, p. 161-163, 2013/03
  • Genes that characterize T3-predominant Graves' thyroid tissues, Matsumoto, C,Ito, M,Yamada, H,Yamakawa, N,Yoshida, H,Date, A,Watanabe, M,Hidaka, Y,Iwatani, Y,Miyauchi, A,Takano, T, Europian Journal of Endocrinology, Vol. 168, No. 2, p. 137-144, 2013/02
  • Interference by Pralidoxime (PAM) salts in clinical laboratory tests., Nagase, S,Kohguchi, K,Tohyama, K,Watanabe, M,Iwatani, Y, Clinical Chimical Acta, 2013/01
  • Associations between autoimmune thyroid disease prognosis and functional polymorphisms of susceptibility genes, CTLA4, PTPN22, CD40, FCRL3, and ZFAT, previously revealed in genome-wide association studies, Naoya Inoue,Mikio Watanabe,Hiroya Yamada,Kazuya Takemura,Fumiaki Hayashi,Noriko Yamakawa,Maiko Akahane,Yu Shimizuishi,Yoh Hidaka,Yoshinori Iwatani, Journal of Clinical Immunology, Vol. 32, No. 6, p. 1243-1252, 2012/12
  • Association of polymorphisms in DNMT1, DNMT3A, DNMT3B, MTHFR and MTRR genes with global DNA methylation levels and prognosis of autoimmune thyroid disease, Y. Arakawa,M. Watanabe,N. Inoue,M. Sarumaru,Y. Hidaka,Y. Iwatani, Clinical and Experimental Immunology, Vol. 170, No. 2, p. 194-201, 2012/11
  • Prolonged hybridization with a cRNA probe improves the signal to noise ratio for in-tube in situ hybridization for quantification of mRNA after fluorescence-activated cell sorting, H. Yamada,N. Yamakawa,M. Watanabe,Y. Hidaka,Y. Iwatani,T. Takano, Biotechnic and Histochemistry, Vol. 87, No. 5, p. 366-371, 2012/07
  • Functional polymorphisms in TBX21 and HLX are associated with development and prognosis of Graves' disease, Mami Morita,Mikio Watanabe,Naoya Inoue,Chisa Inaoka,Takashi Akamizu,Ke-Ita Tatsumi,Yoh Hidaka,Yoshinori Iwatani, Autoimmunity, Vol. 45, No. 2, p. 129-136, 2012/03
  • A solution for distinguishing Le(a-b-) sera in CA19-9 assays using SphereLight 180 and Architect i2000 assays, Hiroyuki Hanada,Satomi Mugii,Keiko Takeoka,Ikuhiro Maeda,Mikio Watanabe,Yoh Hidaka,Yoshinori Iwatani, Clinica Chimica Acta, Vol. 413, No. 1-2, p. 278-281, 2012/01/18
  • Measurement of TFF3 mRNA in aspirates from thyroid nodules using mesh filtration: The first clinical trial in 130 cases, Hiroya Yamada,Toru Takano,Minoru Kihara,Mitsuyoshi Hirokawa,Hiroshi Yoshida,Mikio Watanabe,Yoshinori Iwatani,Yoh Hidaka,Akira Miyauchi, Endocrine Journal, Vol. 59, No. 7, p. 621-630, 2012
  • Association of functional GITR gene polymorphisms related to expression of GITR molecules with prognosis of autoimmune thyroid disease, Rie Tomizawa,Mikio Watanabe,Naoya Inoue,Kazuya Takemura,Yoh Hidaka,Takashi Akamizu,Kazuo Hayakawa,Yoshinori Iwatani, Clinical and Experimental Immunology, 2011/05
  • Association of functional polymorphisms in promoter regions of IL5, IL6 and IL13 genes with development and prognosis of autoimmune thyroid diseases, N. Inoue,M. Watanabe,M. Morita,K. Tatusmi,Y. Hidaka,T. Akamizu,Y. Iwatani, CLINICAL AND EXPERIMENTAL IMMUNOLOGY, WILEY, Vol. 163, No. 3, p. 318-323, 2011/03
  • 臨床検査技師にこそ情報教育を!(臨床検査技師教育機関からの声), 2011/02
  • Transcriptional activity of the 5'-flanking region of the thyroid transcription factor-1 gene in human thyroid cell lines, Hiroya Yamada,Toru Takano,Fumio Matsuzuka,Mikio Watanabe,Akira Miyauchi,Yoshinoroi Iwatani, Genetics and Molecular Biology, SOC BRASIL GENETICA, Vol. 34, No. 1, p. 6-10, 2011/01
  • mRNA quantification after fluorescence activated cell sorting using locked nucleic acid probes, Rie Maruo,Hiroya Yamada,Mikio Watanabe,Yoh Hidaka,Yoshinori Iwatani,Toru Takano, Molecular Biotechnology, 2011/01
  • Transcriptional activity of the 5 &apos;-flanking region of the thyroid transcription factor-1 gene in human thyroid cell lines, Hiroya Yamada,Toru Takano,Fumio Matsuzuka,Mikio Watanabe,Akira Miyauchi,Yoshinori Iwatani, GENETICS AND MOLECULAR BIOLOGY, SOC BRASIL GENETICA, Vol. 34, No. 1, p. 6-10, 2011
  • mRNA quantification after fluorescence activated cell sorting using locked nucleic acid probes, Rie Maruo,Hiroya Yamada,Mikio Watanabe,Yoh Hidaka,Yoshinori Iwatani,Toru Takano, Molecular Biotechnology, 2011/01
  • 第5回日本臨床検査学教育学会学術大会教員研修会レポート(遺伝子検査学分野), 2010/12
  • Association of functional polymorphisms related to the transcriptional level of FOXP3 with prognosis of autoimmune thyroid diseases, N. Inoue,M. Watanabe,M. Morita,R. Tomizawa,T. Akamizu,K. Tatsumi,Y. Hidaka,Y. Iwatani, CLINICAL AND EXPERIMENTAL IMMUNOLOGY, WILEY-BLACKWELL, Vol. 162, No. 3, p. 402-406, 2010/12
  • Messenger RNA quantification after fluorescence activated cell sorting using in situ hybridization, Hiroya Yamada,Rie Maruo,Mikio Watanabe,Yoh Hidaka,Yoshinri Iwatani,Toru Takano, Cytometry Part A, 2010/11
  • Increases in urinary creatinine and blood pressure during early pregnancy in pre-eclampsia, Koichi Kuromoto,Mikio Watanabe,Kazushige Adachi,Kazutomo Ohashi,Yoshinori Iwatani, ANNALS OF CLINICAL BIOCHEMISTRY, SAGE PUBLICATIONS INC, Vol. 47, p. 336-342, 2010/07
  • Messenger RNA quantification after fluorescence activated cell sorting using intracellular antigens, Hiroya Yamada,Rie Maruo,Mikio Watanabe,Yoh Hidaka,Yoshinori Iwatani,Toru Takano, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 397, No. 3, p. 425-428, 2010/07
  • 第4回日本臨床検査学教育学会学術大会イブニングセミナー(遺伝子検査学), 2010/03
  • Drug selection and Laboratory tests -Graves' disease-, Mikio Watanabe, The Yakuji Nippo Medical, 2010/02
  • Postpartum increase of serum thioredoxin concentrations and the relation to CD8 lymphocytes, Shoko Kuroda,Mikio Watanabe,Tomoko Santo,Yu Shimizuishi,Toru Takano,Yoh Hidaka,Tadashi Kimura,Yoshinori Iwatani, ANNALS OF CLINICAL BIOCHEMISTRY, ROYAL SOC MEDICINE PRESS LTD, Vol. 47, p. 62-66, 2010/01
  • Association of the-31C/T functional polymorphism in the interleukin-1 beta gene with the intractability of Graves&apos; disease and the proportion of T helper type 17 cells, F. Hayashi,M. Watanabe,T. Nanba,N. Inoue,T. Akamizu,Y. Iwatani, CLINICAL AND EXPERIMENTAL IMMUNOLOGY, WILEY-BLACKWELL PUBLISHING, INC, Vol. 158, No. 3, p. 281-286, 2009/12
  • Association of the-31C/T functional polymorphism in the interleukin-1 beta gene with the intractability of Graves&apos; disease and the proportion of T helper type 17 cells, F. Hayashi,M. Watanabe,T. Nanba,N. Inoue,T. Akamizu,Y. Iwatani, CLINICAL AND EXPERIMENTAL IMMUNOLOGY, WILEY-BLACKWELL PUBLISHING, INC, Vol. 158, No. 3, p. 281-286, 2009/12
  • Report from Academic Meeting -- The Japanese Society for Gene Diagnosis and Therapy, Mikio Watanabe, Japanese Journal of Medical Technology Education, 2009/09
  • Early detection of metastasis and relapse of colorectal cancer by recognizing NCA-2 in commercially available CEA assay., Hiroyuki Hanada,Satomi Mugii,Keiko Takeoka,Ikuhiro Maeda,Mikio Watanabe,Yoh Hidaka,Yoshinori Iwatani, Clinical Chemistry, 2009/09
  • Expression of nestin mRNA is a differentiation marker in thyroid tumors, Hiroya Yamada,Toru Takano,Yasuhiro Ito,Fumio Matsuzuka,Akihiro Miya,Kaoru Kobayashi,Hiroshi Yoshida,Mikio Watanabe,Yoshinori Iwatani,Akira Miyauchi, CANCER LETTERS, ELSEVIER IRELAND LTD, Vol. 280, No. 1, p. 61-64, 2009/07
  • Thyroid diseases during and after pregnancy, Mikio Watanabe,Yoshinori Iwatani, Sogo Rinsho, 2009/07
  • Increases of the Th1/Th2 Cell Ratio in Severe Hashimoto&apos;s Disease and in the Proportion of Th17 Cells in Intractable Graves&apos; Disease, Takashi Nanba,Mikio Watanabe,Naoya Inoue,Yoshinori Iwatani, THYROID, MARY ANN LIEBERT INC, Vol. 19, No. 5, p. 495-501, 2009/05
  • Involvement of functional polymorphisms in the TNFA gene in the pathogenesis of autoimmune thyroid diseases and production of anti-thyrotropin receptor antibody, N. Inoue,M. Watanabe,T. Nanba,M. Wada,T. Akamizu,Y. Iwatani, CLINICAL AND EXPERIMENTAL IMMUNOLOGY, WILEY-BLACKWELL PUBLISHING, INC, Vol. 156, No. 2, p. 199-204, 2009/05
  • Clinical utility and characteristics of nine anti-HCV antibody screening reagents used in Japan, Mifumi Kita,Matsuo Deguchi,Masanori Kagita,Nori Yoshioka,Eiji Kobayashi,Mikio Watanabe,Seishi Asari,Kiyoharu Yamanaka,Yoshinori Iwatani, Clinical Laboratory, Vol. 55, No. 1-2, p. 9-22, 2009
  • Laboratory tests viewed in symptom - Weight loss -, Mikio Watanabe, The YAKUJI NIPPO MEDICAL, 株式会社薬事日報社, 2008/11
  • Patients of Hashimto's disease with -599CC genotype in the IL4 gene would develop hypothyroidis, Mikio Watanabe,Takashi Nanba,Takashi Akamizu,Yoshinori Iwatani, 2008/10
  • A Novel microfluidic immunoassay to determine AFP-L3% in serum samples., Hanada, H,Kagebayashi, C,Kurosawa, T,Kawabata, T,Kitano, H,Li, C,Bousse, L,Watanabe, M,Maeda, I,Takeoka, K,Watanabe, M,Wada, H. G,Hidaka, Y,Iwatani, Y,Satomura, S, 2008/07
  • A new predictive indicator for development of pressure ulcers in bedridden patients based on common laboratory tests results, N. Hatanaka,Y. Yamamoto,K. Ichihara,S. Mastuo,Y. Nakamura,M. Watanabe,Y. Iwatani, JOURNAL OF CLINICAL PATHOLOGY, B M J PUBLISHING GROUP, Vol. 61, No. 4, p. 514-518, 2008/04
  • The -590CC Genotype in Interleukin-4 Gene as a Strong Predictive Factor for the Development of Hypothyroidism in Hashimoto's Disease, Takashi Nanba,Mikio Watanabe,Takashi Akamizu,Yoshinori Iwatani, Clinical Chemistry, 2008/03
  • The +869T/C polymorphism in the transforming growth factor-β1 gene is associated with the severity and intractability of autoimmune thyroid disease, H. Yamada,M. Watanabe,T. Nanba,T. Akamizu,Y. Iwatani, Clinical and Experimental Immunology, Vol. 151, No. 3, p. 379-382, 2008/03
  • 5種のHIVスクリーニング検査試薬の評価, 2008/02
  • 6種類のTreponema Pallidum(TP)抗体測定法の比較, 2008/01
  • Decrease of intrathyroidal CD161+Vα24+Vβ 11+ NKT cells in Graves' disease, Mikio Watanabe,Yukiyo Nakamura,Fumio Matsuzuka,Yuuki Takamura,Akira Miyauchi,Yoshinori Iwatani, Endocrine Journal, Vol. 55, No. 1, p. 199-203, 2008
  • Ratio of serum IgG3 to total IgG concentration ond goiter size are independent factors in intractability of Graves' disease., Santoh, T,Watanabe, M,Kuroda, S,Ueda, D,Iwatani, Y, Endocrine Journal, JAPAN ENDOCRINE SOC, Vol. 54, No. 6, p. 887-894, 2007/12
  • Evaluation of a chemiluminescent microparticle immunoassay for determination of Treponema pallidum antibodies, Nori Yoshioka,Matsuo Deguchi,Masanori Kagita,Mifumi Kita,Mikio Watanabe,Seishi Asari,Yoshinori Iwatani, Clinical Laboratory, CLIN LAB PUBL, Vol. 53, No. 9-12, p. 597-603, 2007/11
  • Study on physiology and psychological effect of lawn ground and lavender field in city park, IWASAKI Yutaka,YAMAMOTO Satoshi,ISHI Mayuko,WATANABE Mikio, Journal of the Japanese Society of Revegetation Technology, The Japanese Society of Revegetation Technology, Vol. 33, No. 1, p. 116-121, 2007/08/31
  • 橋本病の発症機序, 2007/08
  • Clinical significance of CEA-family measurement as a marker for metastasis and relapse of cancer., Hanada, H,Takeoka, K,Nomura, T,Yamashita, Y,Namba, T,Watanabe, M,Iwatani Y,Hidaka, Y, 2007/07
  • 化学発光酵素免疫測定法によるHCV core抗原測定法の評価, 2007/05
  • 化学発光免疫測定試薬「アーキテクトHBc-M」の基本性能と臨床的有用性の評価, 2007/03
  • 化学発光免疫測定試薬「アーキテクトHBe AgおよびHBe Ab」の基本性能と臨床的有用性, 2007/01
  • Apoptosis-induced decrease of intrathyroidal CD4(+)CD25(+) regulatory T cells in autoimmune thyroid diseases, Aiko Nakano,Mikio Watanabe,Takao Iida,Shoko Kuroda,Fumio Matsuzuka,Akira Miyauchi,Yoshinori Iwatani, THYROID, MARY ANN LIEBERT INC, Vol. 17, No. 1, p. 25-31, 2007/01
  • HCV抗体測定における3種化学発光法の比較, 2006/11
  • Association between the severity of Hashimoto's disease and the functional +874A/T polymorphism in the interferon-gamma gene, Chisato Ito,Mikio Watanabe,Noriko Okuda,Chikami Watanabe,Yoshinori Iwatani, ENDOCRINE JOURNAL, JAPAN ENDOCRINE SOCIETY, Vol. 53, No. 4, p. 473-478, 2006/08
  • オーソクイックチェイサーHCV AbによるC型肝炎ウイルス(HCV)抗体高力価判定基準の設定, 2006/02
  • Chemiluminescent Enzyme Immunoassay (CLEIA)による風疹ウィルス抗体測定の基礎的検討, 2006/02
  • Association between the severity of Hashimoto's disease and the functional +874A/T polymorphism in the interferon-γ gene, Chisato Ito,Mikio Watanabe,Noriko Okuda,Chikami Watanabe,Yoshinori Iwatani, Endocrine Journal, Vol. 53, No. 4, p. 473-478, 2006
  • A useful new classification of dysmorphic urinary erythrocytes, Daisuke Nagahama,Kenichi Yoshiko,Mikio Watanabe,Yoshiki Morita,Yoshinori Iwatani,Seiichi Matsuo, Clinical and Experimental Nephrology, Vol. 9, No. 4, p. 304-309, 2005/12
  • Study on the effects for human physiology from green in urban parks, Satoshi Yamamoto,Yutaka Iwasaki,Hyojung Kweon,Mikio Watanabe, Landscape Plannning & Horticulture, 2005/03
  • Intrathyroidal CD4(+) T lymphocytes express high levels of Fas and CD4(+)CD8(+) macrophages/dendritic cells express fas ligand in autoimmune thyroid disease, Y Nakamura,M Watanabe,F Matsuzuka,H Maruoka,A Miyauchi,Y Iwatani, THYROID, MARY ANN LIEBERT INC, Vol. 14, No. 10, p. 819-824, 2004/10
  • 大学教員の看護実習におけるストレスに対するコルチゾールを用いた評価, 2004/09
  • Lower concentration of serum soluble CD8 in severe Hashimoto's disease, N Yamamoto,M Watanabe,F Matsuzuka,A Miyauchi,Y Iwatani, CLINICAL AND EXPERIMENTAL IMMUNOLOGY, BLACKWELL PUBLISHING LTD, Vol. 137, No. 3, p. 601-605, 2004/09
  • Effects of plant's aroma on anti-stress with Plant's leaf tearing task., Iwasaki, Y,Yamamoto, S,Kweon, H,Watanabe, M,Asano, F, 2004/06
  • Increased intensities of fas expression on peripheral T-cell subsets in severe autoimmune thyroid disease, H Maruoka,M Watanabe,F Matsuzuka,T Takimoto,A Miyauchi,Y Iwatani, THYROID, MARY ANN LIEBERT, INC, Vol. 14, No. 6, p. 417-423, 2004/06
  • Decrease of CD154 intensity on peripheral CD4(+) T cells in autoimmune thyroid disease, M Watanabe,N Yamamoto,F Matsuzuka,A Miyauchi,Y Iwatani, CLINICAL AND EXPERIMENTAL IMMUNOLOGY, BLACKWELL PUBLISHING LTD, Vol. 136, No. 3, p. 555-558, 2004/06
  • Increase of serum Interleukin-10 in intractable Graves' disease., Takeoka, K,Watanabe, M,Matsuzuka, F,Miyauchi, A,Iwatani, Y, Thyroid, MARY ANN LIEBERT INC PUBL, Vol. 14, No. 3, p. 201-205, 2004/03
  • Study on stress easing effect by aroma of revegetation trees in city, Yutaka Iwasaki,Satoshi Yamamoto,Mikio Watanabe, AROMA RESEARCH, Vol. 5, No. 4, p. 386-390, 2004
  • Physiological changes of Fas expression in peripheral lymphocyte subsets during the menstrual cycle, R Shinoda,M Watanabe,Y Nakamura,H Maruoka,Y Kimura,Y Iwatani, JOURNAL OF REPRODUCTIVE IMMUNOLOGY, ELSEVIER SCI IRELAND LTD, Vol. 60, No. 2, p. 159-168, 2003/12
  • Basic study on human psychological and physiological characteristics in responses to existing plants in urban parks., Yamamoto, S,Iwasaki, Y,Mino, N,Watanabe, M, Journal of the Japanese Institute of Landscape Architecture, International Edition, 2, 25-30, 2003, 2003/10
  • High frequency of antibiotic-associated diarrhea due to toxin A-negative, toxin B-positive Clostridium difficile in a hospital in Japan and risk factors for infection, M Komatsu,H Kato,M Aihara,K Shimakawa,M Iwasaki,Y Nagasaka,S Fukuda,S Matsuo,Y Arakawa,M Watanabe,Y Iwatani, EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, SPRINGER-VERLAG, Vol. 22, No. 9, p. 525-529, 2003/09
  • Seroprevalence survey of measles, rubella, varicella, and mumps antibodies in health care workers and evaluation of a vaccination program in a tertiary care hospital in Japan, S Asari,M Deguchi,K Tahara,M Taniike,M Toyokawa,Nishi, I,M Watanabe,Y Iwatani,K Makimoto, AMERICAN JOURNAL OF INFECTION CONTROL, MOSBY, INC, Vol. 31, No. 3, p. 157-162, 2003/05
  • Increase in immunoglobulin G3-secreting cells in intractable Graves' disease, Y Nakamoto,M Niki,M Watanabe,Y Iwatani, THYROID, MARY ANN LIEBERT INC PUBL, Vol. 13, No. 4, p. 325-331, 2003/04
  • Basic study on human psychological and physiological characteristics in responses to existing plants in urban parks, Yamamoto, S,Iwasaki, Y,Mino, N,Watanabe, M, 2003/03
  • Do Not Apply The Reference Values Of Labotarory Tests For Young To Elders, Mikio Watanabe, 2003/03
  • Relation of CD30 molecules on T-cell subsets to the severity of autoimmune thyroid disease, M Watanabe,N Yamamoto,H Maruoka,F Matsuzuka,A Miyauchi,Y Iwatani, THYROID, MARY ANN LIEBERT INC PUBL, Vol. 13, No. 3, p. 259-263, 2003/03
  • Differential Diagnosis And Treatment Of Thyrotoxicosis, Mikio Watanabe, 2002/08
  • Independent involvement of CD8+CD25+ cells and thyroid autoantibodies in disease severity of Hashimoto's disease, Mikio Watanabe,Naoko Yamamoto,Hayato Maruoka,Hajime Tamai,Fumio Matsuzuka,Akira Miyauchi,Yoshinori Iwatani, Thyroid, Vol. 12, No. 9, p. 801-808, 2002
  • Increase of CD5+ B cells during adolescence in female mice, Kiyoshi Watanabe,Mikio Watanabe,Hayato Maruoka,Nobuyuki Amino,Yoshinori Iwatani, Mechanisms of Ageing and Development, Vol. 122, No. 15, p. 1787-1795, 2001
  • Increased intensity of Fas expression on peripheral T cell subsets in severe autoimmune thyroid disease., Mikio Watanabe,Hayato Maruoka,Naoko Yamamoto,Fumio Matsuzuka,Hajime Tamai,Takimoto, T,Kanji Kuma,Yoshinori Iwatani, 2000/10
  • Atherosclerosis And CD40, Mikio Watanabe,Yoshinori Iwatani, 1999/07
  • The maternal immune system in health and disease, Y Iwatani,M Watanabe, CURRENT OPINION IN OBSTETRICS & GYNECOLOGY, LIPPINCOTT WILLIAMS & WILKINS, Vol. 10, No. 6, p. 453-458, 1998/12
  • Necessity Of Training For Using Computer Network With Manner, WATANABE Mikio, 1998/10
  • Free T4 And Free T3, Yoshinori Iwatani,Mikio Watanabe, 1998/04
  • Lymphocyte Subsets, Mikio Watanabe,Yoshinori, Iwatani, 1998/04
  • Opposite changes in serum soluble CD8 in patients at the active stages of Graves' and Hashimoto's diseases, M Watanabe,N Amino,K Hochito,K Watanabe,K Kuma,Y Iwatani, THYROID, MARY ANN LIEBERT INC PUBL, Vol. 7, No. 5, p. 743-747, 1997/10
  • Changes in T, B, and NK lymphocyte subsets during and after normal pregnancy, Mikio Watanabe,Yoshinori Iwatani,Tatsunari Kaneda,Yoh Hidaka,Nobuaki Mitsuda,Yasuhiko Morimoto,Nobuyuki Amino, American Journal of Reproductive Immunology, Blackwell Publishing Ltd, Vol. 37, No. 5, p. 368-377, 1997
  • Changes in soluble CD4 and CD8 proteins in healthy pregnant and postpartum women, M Watanabe,Y Iwatani,Y Hidaka,N Mitsuda,N Amino, AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY, WILEY-BLACKWELL, Vol. 36, No. 4, p. 220-227, 1996/10
  • A Patient With Postpartum Central Hypoadrenalism, Mikio Watanabe,Takashi Iijima,Taku Kashiwai,Motoko Kimura,Yoshinori Iwatani,Nobuyuki Amino, 1995/05
  • A Patient With Euthyroid Graves' Disease Showing No Thyroid Abnormalities Except Positive Thyroid Stimulating Antibody (TSAb), Mikio Watanabe,Takashi Iijima,Taku Kashiwai,Haruo Tamaki,Takashi Fujikado,Yoshinori Iwatani,Nobuyuki Amino, 1995/02
  • Euthyroid Graves' disease showing no thyroid abnormalities except positive thyroid‐stimulating antibody (TSAb): two case reports, MIKIO WATANABE,YOSHINORI IWATANL,TAKU KASHIWAI,TAKASHI IIJIMA,TAKASHI FUJIKADO,NOBUYUKI AMINO, Journal of Internal Medicine, Vol. 238, No. 4, p. 379-384, 1995
  • Long-Term Effects of Thyroid Hormone on Lymphocyte Subsets in Spleens and Thymuses of Mice, Kiyoshi Watanabe,Yoh Hidaka,Mikio Watanabe,Nobuyuki Amino,Yoshinori Iwatani, Endocrine Journal, Vol. 42, No. 5, p. 661-668, 1995

Misc.

  • 自己免疫性甲状腺疾患におけるCD80およびCD86の遺伝子多型および蛋白発現解析, 井上 直哉,渡邉 幹夫,日高 洋,岩谷 良則, 臨床化学, (一社)日本臨床化学会, Vol. 48, No. Suppl.1, p. 239-239, 2019/08
  • CTLA4CT60遺伝子多型に関連するCpGのメチル化率が自己免疫性甲状腺疾患の病因病態に及ぼす影響, 大谷 洸樹,渡邉 幹夫,井上 直哉,木之下 陸,日高 洋,岩谷 良則, 臨床化学, (一社)日本臨床化学会, Vol. 48, No. Suppl.1, p. 202-202, 2019/08
  • 自己免疫性甲状腺疾患の病態とB7H3、B7H4遺伝子多型との関連, 尾崎 悠,川口 隼佳,渡邉 幹夫,井上 直哉,日高 洋,岩谷 良則, 日本内分泌学会雑誌, (一社)日本内分泌学会, Vol. 94, No. 4, p. 1225-1225, 2018/12
  • 自己免疫性甲状腺疾患の発症・病態予後とIL10プロモーター領域のCpGのメチル化率との関連, 木之下 陸,渡邉 幹夫,井上 直哉,日高 洋,岩谷 良則, 日本内分泌学会雑誌, (一社)日本内分泌学会, Vol. 94, No. 4, p. 1225-1225, 2018/12
  • 自己免疫性甲状腺疾患の発症・病態予後とIL6プロモーター領域のCpGのメチル化率との関連, 平井 那知,渡邉 幹夫,井上 直哉,木之下 陸,大谷 洸樹,日高 洋,岩谷 良則, 臨床化学, (一社)日本臨床化学会, Vol. 47, No. Suppl.1, p. 234-234, 2018/07
  • 自己免疫性甲状腺疾患の疾患感受性・病態予後とB7H4遺伝子多型の関連, 尾崎 悠,渡邉 幹夫,井上 直哉,渡辺 彩乃,日高 洋,岩谷 良則, 臨床化学, (一社)日本臨床化学会, Vol. 47, No. Suppl.1, p. 254-254, 2018/07
  • 自己免疫性甲状腺疾患の病態予後とIL17A、IL17F、RORC遺伝子多型との関連, 井上 直哉,渡邉 幹夫,日高 洋,岩谷 良則, 臨床化学, (一社)日本臨床化学会, Vol. 47, No. Suppl.1, p. 293-293, 2018/07
  • 自己免疫性甲状腺疾患の疾患感受性・病態予後とB7H4遺伝子多型の関連, 尾崎 悠,渡邉 幹夫,井上 直哉,渡辺 彩乃,日高 洋,岩谷 良則, 臨床化学, (一社)日本臨床化学会, Vol. 47, No. Suppl.1, p. 352-352, 2018/07
  • ビタミンAの代謝に関する遺伝子多型を用いた自己免疫性甲状腺疾患の病態解析, 本間 日向子,渡邉 幹夫,井上 直哉,日高 洋,岩谷 良則, 日本内分泌学会雑誌, (一社)日本内分泌学会, Vol. 93, No. 4, p. 1123-1123, 2017/12
  • 自己免疫性甲状腺疾患の感受性とHLA-DQA1*01、*03の遺伝子型との関連, 野口 祐介,渡邉 幹夫,井上 直哉,荒川 裕也,泊 沙希,山中 千佳,日高 洋,岩谷 良則, 日本内分泌学会雑誌, (一社)日本内分泌学会, Vol. 93, No. 4, p. 1123-1123, 2017/12
  • Genetic background specific for TgAb discordant twins, Mikio Watanabe,Yoichi Takenaka,Chika Honda,Yoshinori Iwatani, BEHAVIOR GENETICS, SPRINGER, Vol. 47, No. 6, p. 644-644, 2017/11
  • CD58遺伝子多型および末梢血単核球CD58発現と自己免疫性甲状腺疾患の発症・病態予後との関連, 山本 麻由,渡邉 幹夫,井上 直哉,渡辺 彩乃,日高 洋,岩谷 良則, 臨床病理, 日本臨床検査医学会, Vol. 65, No. 補冊, p. 133-133, 2017/10
  • TLR7、TLR9遺伝子多型と自己免疫性甲状腺疾患の病態との関連, 井上 直哉,勝又 由佳,渡邉 幹夫,日高 洋,岩谷 良則, 臨床病理, 日本臨床検査医学会, Vol. 65, No. 補冊, p. 134-134, 2017/10
  • 末梢血単核球ヒストンのアセチル化量の個体内変動, 羽賀 絵美,渡邉 幹夫,井上 直哉,日高 洋,岩谷 良則, 臨床病理, 日本臨床検査医学会, Vol. 65, No. 補冊, p. 242-242, 2017/10
  • IFNG-54CpGのDNAメチル化率と自己免疫性甲状腺疾患の発症・病態予後との関連, 橋本 秀美,渡邉 幹夫,井上 直哉,森田 詠美,日高 洋,岩谷 良則, 臨床化学, (一社)日本臨床化学会, Vol. 46, No. Suppl.1, p. 259-259, 2017/09
  • 自己免疫性甲状腺疾患の病態とTLR7遺伝子多型との関連, 井上 直哉,渡邉 幹夫,勝又 由佳,日高 洋,岩谷 良則, 臨床化学, (一社)日本臨床化学会, Vol. 46, No. Suppl.1, p. 272-272, 2017/09
  • VEGF遺伝子多型と自己免疫性甲状腺疾患の発症・病態予後との関連, 岡本 真実,渡邉 幹夫,井上 直哉,日高 洋,岩谷 良則, 臨床化学, (一社)日本臨床化学会, Vol. 46, No. Suppl.1, p. 274-274, 2017/09
  • 自己免疫性甲状腺疾患の発症・病態予後と末梢血単核球上のCD58発現との関連, 山本 麻由,渡邉 幹夫,井上 直哉,渡辺 彩乃,日高 洋,岩谷 良則, 臨床化学, (一社)日本臨床化学会, Vol. 46, No. Suppl.1, p. 352-352, 2017/09
  • 機能的IL-15遺伝子多型とIL-17細胞増殖と橋本病の重症度との関連, 荒川 裕也,渡邉 幹夫,武村 和哉,井上 直哉,日高 洋,岩谷 良則, 臨床化学, (一社)日本臨床化学会, Vol. 46, No. 3, p. 231-237, 2017/07
  • 自己免疫性甲状腺疾患の病因・病態とICOSおよびICOSL遺伝子上の多型との関連, 渡邉 幹夫,吉江 南希,井上 直哉,川口 隼佳,日高 洋,岩谷 良則, 日本内分泌学会雑誌, (一社)日本内分泌学会, Vol. 93, No. 1, p. 357-357, 2017/04
  • AGO2遺伝子の発現および多型と自己免疫性甲状腺疾患の病態との関連, 時吉 恵奈,渡邉 幹夫,井上 直哉,日高 洋,岩谷 良則, 日本内分泌学会雑誌, (一社)日本内分泌学会, Vol. 92, No. 3, p. 607-607, 2017/01
  • 自己免疫性甲状腺疾患の病態とCD80、CD86遺伝子多型との関連, 渡辺 彩乃,渡邉 幹夫,井上 直哉,日高 洋,岩谷 良則, 日本内分泌学会雑誌, (一社)日本内分泌学会, Vol. 92, No. 3, p. 607-607, 2017/01
  • マイクロRNA let-7eの発現量はIL-10産生能および橋本病の疾患感受性と関係する, 渡邉 幹夫,香川 朋也,井上 直哉,大津 裕,佐伯 みのり,勝又 由佳,田久世 友希奈,岩谷 良則, 日本内分泌学会雑誌, (一社)日本内分泌学会, Vol. 92, No. 3, p. 622-622, 2017/01
  • Sex-related individual differences in DNA methylation in monozygotic twin pairs, Mikio Watanabe,Chika Honda,Yoshinori Iwatani, BEHAVIOR GENETICS, SPRINGER, Vol. 46, No. 6, p. 813-813, 2016/11
  • 橋本病の重症度に及ぼす、Th17細胞の増殖を介したIL-15の影響, 荒川 裕也,渡邉 幹夫,武村 和哉,井上 直哉,岩谷 良則, 臨床化学, (一社)日本臨床化学会, Vol. 45, No. Suppl.1, p. 169-169, 2016/10
  • FAS、FASL遺伝子多型と自己免疫性甲状腺疾患の病態との関連, 井上 直哉,渡邉 幹夫,石戸 奈穂子,丸岡 隼人,勝又 由佳,日高 洋,岩谷 良則, 臨床化学, (一社)日本臨床化学会, Vol. 45, No. Suppl.1, p. 194-194, 2016/10
  • IFNG遺伝子のDNAメチル化率と自己免疫性甲状腺疾患の発症・病態予後との関連, 橋本 秀美,渡邉 幹夫,井上 直哉,森田 詠美,日高 洋,岩谷 良則, 臨床化学, (一社)日本臨床化学会, Vol. 45, No. Suppl.1, p. 195-195, 2016/10
  • 自己免疫性甲状腺疾患の発症および病態とCRTH2遺伝子多型との関連, 大森 名起,渡邉 幹夫,井上 直哉,岡本 真美,日高 洋,岩谷 良則, 臨床化学, (一社)日本臨床化学会, Vol. 45, No. Suppl.1, p. 196-196, 2016/10
  • 自己免疫性甲状腺疾患の病態とHLA-DQB1 *0301、0302、0303 carrierとの関連, 山中 千佳,渡邉 幹夫,井上 直哉,荒川 裕也,泊 沙希,野口 祐介,日高 洋,岩谷 良則, 臨床化学, (一社)日本臨床化学会, Vol. 45, No. Suppl.1, p. 197-197, 2016/10
  • 自己免疫性甲状腺疾患の病態とAGO2遺伝子多型との関連, 時吉 恵奈,渡邉 幹夫,井上 直哉,日高 洋,岩谷 良則, 臨床病理, 日本臨床検査医学会, Vol. 64, No. 補冊, p. 16-2, 2016/09
  • 甲状腺ペルオキシダーゼ遺伝子多型と自己免疫性甲状腺疾患の発症・予後との関連, 泊 沙希,渡邉 幹夫,井上 直哉,日高 洋,岩谷 良則, 臨床検査学教育, (一社)日本臨床検査学教育協議会, Vol. 8, No. 1, p. 101-102, 2016/03
  • P1-34 末梢血microRNA Let-7e発現量とIL-10産生量および橋本病の病因との関係, Vol. 39, No. 4, p. 391b-391b, 2016
  • 末梢血単核球中miR-106a発現およびmiR106a遺伝子多型と自己免疫性甲状腺疾患の病態との関連, 田久世 友希奈,渡邉 幹夫,井上 侑加,大津 裕,佐伯 みのり,井上 直哉,日高 洋,岩谷 良則, 日本内分泌学会雑誌, (一社)日本内分泌学会, Vol. 91, No. 2Suppl., p. 72-72, 2015/11
  • TNFA遺伝子のメチル化率が自己免疫性甲状腺疾患の病態に及ぼす影響, 森田 詠美,渡邉 幹夫,井上 直哉,橋本 秀美,日高 洋,岩谷 良則, 日本内分泌学会雑誌, (一社)日本内分泌学会, Vol. 91, No. 2Suppl., p. 72-72, 2015/11
  • X染色体不活性化の偏りとバセドウ病や橋本病の病態予後との関連, 渡邉 幹夫,石戸 奈穂子,井上 直哉,日高 洋,岩谷 良則, 日本内分泌学会雑誌, (一社)日本内分泌学会, Vol. 91, No. 2Suppl., p. 78-78, 2015/11
  • ビタミンD関連分子における機能的な遺伝子多型と自己免疫性甲状腺疾患の病態予後との関連, 井上 直哉,渡邉 幹夫,石戸 奈穂子,勝又 由佳,香川 朋也,日高 洋,岩谷 良則, 日本内分泌学会雑誌, (一社)日本内分泌学会, Vol. 91, No. 2Suppl., p. 96-96, 2015/11
  • サイログロブリン遺伝子多型と自己免疫性甲状腺疾患の発症・予後との関連, 泊 沙希,渡邉 幹夫,井上 直哉,荒川 裕也,水間 知世,日高 洋,岩谷 良則, 臨床病理, 日本臨床検査医学会, Vol. 63, No. 補冊, p. 181-181, 2015/10
  • DICER1およびDROSHA遺伝子の多型および発現と自己免疫性甲状腺疾患の病態との関連, 佐伯 みのり,渡邉 幹夫,澁谷 さやか,大津 裕,井之上 侑加,井上 直哉,日高 洋,岩谷 良則, 臨床化学, (一社)日本臨床化学会, Vol. 44, No. Suppl.1, p. 199-199, 2015/10
  • 自己免疫性甲状腺疾患の病態予後とケモカイン遺伝子多型との関連, 井上 直哉,渡邉 幹夫,赤羽 舞子,宮原 由美,荒川 裕也,井上 侑加,勝又 由佳,日高 洋,岩谷 良則, 臨床化学, (一社)日本臨床化学会, Vol. 44, No. Suppl.1, p. 203-203, 2015/10
  • 自己免疫性甲状腺疾患におけるTNFA遺伝子のメチル化率の解析, 森田 詠美,渡邉 幹夫,井上 直哉,橋本 秀美,日高 洋,岩谷 良則, 臨床化学, (一社)日本臨床化学会, Vol. 44, No. Suppl.1, p. 204-204, 2015/10
  • 甲状腺ペルオキシダーゼ遺伝子多型と自己免疫性甲状腺疾患の発症・予後との関連, 泊 沙希,渡邉 幹夫,井上 直哉,山中 千佳,日高 洋,岩谷 良則, 臨床化学, (一社)日本臨床化学会, Vol. 44, No. Suppl.1, p. 204-204, 2015/10
  • TSHレセプター遺伝子のエンハンサーに存在する遺伝子多型と自己免疫性甲状腺疾患との関連, 藤井 亜沙美,渡邉 幹夫,井上 直哉,日高 洋,岩谷 良則, 臨床化学, (一社)日本臨床化学会, Vol. 44, No. Suppl.1, p. 205-205, 2015/10
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  • 自己免疫性甲状腺疾患の病態とTLR4遺伝子多型との関連, 勝又 由佳,渡邉 幹夫,井上 直哉,石戸 奈穂子,日高 洋,岩谷 良則, 臨床病理, 日本臨床検査医学会, Vol. 62, No. 補冊, p. 238-238, 2014/10
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  • HLA-DRB1のペプチド結合部位におけるアミノ酸配列と自己免疫性甲状腺疾患の発症・予後との関連, 矢野 由希子,稲岡 知紗,渡邉 幹夫,井上 直哉,荒川 裕也,水間 知世,日高 洋,岩谷 良則, 日本内分泌学会雑誌, (一社)日本内分泌学会, Vol. 90, No. 2, p. 502-502, 2014/09
  • DICER1およびDROSHA遺伝子の発現および多型と自己免疫性甲状腺疾患の病態との関連, 佐伯 みのり,渡邉 幹夫,大津 裕,井之上 侑加,澁谷 さやか,井上 直哉,日高 洋,岩谷 良則, 日本内分泌学会雑誌, (一社)日本内分泌学会, Vol. 90, No. 2, p. 504-504, 2014/09
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  • 自己免疫性甲状腺疾患の甲状腺組織におけるB7-H3の発現, 吉江 南希,渡邉 幹夫,井上 直哉,日高 洋,高村 勇貴,宮内 昭,岩谷 良則, 日本内分泌学会雑誌, (一社)日本内分泌学会, Vol. 90, No. 2, p. 511-511, 2014/09
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  • ICOS遺伝子の遺伝子多型と自己免疫性甲状腺疾患との関連, 吉江 南希,川口 隼佳,渡邉 幹夫,井上 直哉,日高 洋,岩谷 良則, 臨床化学, (一社)日本臨床化学会, Vol. 43, No. Suppl.1, p. 224-224, 2014/08
  • 末梢血単核球におけるmiR-16の発現と自己免疫性甲状腺疾患の予後との関連, 佐伯 みのり,渡邉 幹夫,澁谷 さやか,井之上 侑加,大津 裕,井上 直哉,岩谷 良則, 臨床化学, (一社)日本臨床化学会, Vol. 43, No. Suppl.1, p. 224-224, 2014/08
  • 自己免疫性甲状腺疾患の病態とHLA-DR血清型との関連, 矢野 由希子,渡邉 幹夫,井上 直哉,荒川 裕也,稲岡 知紗,水間 知世,岩谷 良則, 臨床化学, (一社)日本臨床化学会, Vol. 43, No. Suppl.1, p. 225-225, 2014/08
  • P3-002 バセドウ病と橋本病の感受性にそれぞれ異なる関連を示すTSHR遺伝子の機能的多型, Vol. 37, No. 4, p. 341b-341b, 2014
  • GITR遺伝子の多型がGITRの発現および自己免疫性甲状腺疾患の予後に及ぼす影響, 渡邉 幹夫,富澤 理恵,井上 直哉,武村 和哉,日高 洋,早川 和生,岩谷 良則, 日本臨床免疫学会会誌, 日本臨床免疫学会, Vol. 36, No. 5, p. 387-387, 2013/10
  • GITR遺伝子に存在する機能的なSNPと自己免疫性甲状腺疾患の予後との関連, 井上 直哉,渡邉 幹夫,冨澤 理恵,武村 和哉,末久 悦次,日高 洋,早川 和生,岩谷 良則, 臨床病理, 日本臨床検査医学会, Vol. 61, No. 補冊, p. 238-238, 2013/09
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  • サイログロブリンの遺伝子多型と自己免疫性甲状腺疾患の発症・予後との関連, 水間 知世,渡邉 幹夫,井上 直哉,荒川 裕也,矢野 由希子,泊 沙希,日高 洋,岩谷 良則, 臨床病理, 日本臨床検査医学会, Vol. 61, No. 補冊, p. 240-240, 2013/09
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  • B7-H3遺伝子における遺伝子多型と自己免疫性甲状腺疾患との関連, 川口 隼佳,渡邉 幹夫,川端 麻友美,井上 直哉,日高 洋,岩谷 良則, 臨床化学, (一社)日本臨床化学会, Vol. 42, No. Suppl.1, p. 181-181, 2013/07
  • PD-1遺伝子の機能的多型及びPD-1発現強度と自己免疫性甲状腺疾患の病因・病態との関連, 川端 麻友美,渡邉 幹夫,小林 彩香,井上 直哉,日高 洋, 臨床化学, (一社)日本臨床化学会, Vol. 42, No. Suppl.1, p. 200-200, 2013/07
  • 自己免疫性甲状腺疾患における病態とskewed X-chromosome inactivationとの関係, 石戸 奈穂子,井上 直哉,渡邉 幹夫,日高 洋,岩谷 良則, 臨床病理, 日本臨床検査医学会, Vol. 60, No. 補冊, p. 143-143, 2012/10
  • 自己免疫性甲状腺疾患の予後と疾患感受性遺伝子CTLA4、PTPN22、FCRL3、CD40、ZFATの一塩基多型との関連, 井上 直哉,渡邉 幹夫,武村 和哉,末久 悦次,日高 洋,岩谷 良則, 臨床病理, 日本臨床検査医学会, Vol. 60, No. 補冊, p. 144-144, 2012/10
  • PDCD1遺伝子の-606A/G多型と+7558C/T多型が自己免疫性甲状腺疾患の予後及びPD-1発現に及ぼす影響, 川端 麻友美,渡邉 幹夫,小林 彩香,井上 直哉,日高 洋,岩谷 良則, 臨床病理, 日本臨床検査医学会, Vol. 60, No. 補冊, p. 144-144, 2012/10
  • 全ゲノム関連解析による自己免疫性甲状腺疾患関連遺伝子 CTLA4、PTPN22、CD40、FCRL3、ZFATの機能的多型と病態予後との関係, 渡邉 幹夫,井上 直哉,山田 宏哉,武村 和哉,林 文明,山川 法子,赤羽 舞子,清水石 裕,日高 洋,岩谷 良則, 日本内分泌学会雑誌, (一社)日本内分泌学会, Vol. 88, No. 2, p. 497-497, 2012/09
  • 全ゲノム関連解析による自己免疫性甲状腺疾患関連遺伝子(CTLA4、PTPN22、CD40、FCRL3、ZFAT)の機能的多型と病態予後との関連, 渡邉 幹夫,井上 直哉,山田 宏哉,武村 和哉,林 文明,山川 法子,赤羽 舞子,清水石 裕,日高 洋,岩谷 良則, 日本臨床免疫学会会誌, 日本臨床免疫学会, Vol. 35, No. 4, p. 327-327, 2012/08
  • CTLA4、PTPN22、CD40、FCRL3、ZFAT遺伝子の個体差と自己免疫性甲状腺疾患の病態予後との関連, 井上 直哉,渡邉 幹夫,武村 和哉,林 貞夫,日高 洋,岩谷 良則, 臨床化学, (一社)日本臨床化学会, Vol. 41, No. Suppl.1, p. 236-236, 2012/07
  • PDCD1+7558C/T多型が自己免疫性甲状腺疾患の予後及びPD-1発現に及ぼす影響, 川端 麻友美,渡邉 幹夫,小林 彩花,井上 直哉,日高 洋,岩谷 良則, 臨床化学, (一社)日本臨床化学会, Vol. 41, No. Suppl.1, p. 236-236, 2012/07
  • バセドウ病、橋本病の重症度とIL5、IL6、IL13遺伝子の機能的な多型との関連, 井上 直哉,渡邉 幹夫,日高 洋,巽 圭太,井山 茂,林 貞夫,岩谷 良則, 臨床病理, 日本臨床検査医学会, Vol. 59, No. 補冊, p. 129-129, 2011/10
  • Dnmt1、3a、3bの遺伝子多型と自己免疫性甲状腺疾患の病態との関連, 荒川 裕也,渡邉 幹夫,井上 直哉,日高 洋,巽 圭太,岩谷 良則, 臨床病理, 日本臨床検査医学会, Vol. 59, No. 補冊, p. 130-130, 2011/10
  • IL5、IL6、IL13遺伝子プロモータ領域の一塩基多型を用いた自己免疫性甲状腺疾患の病態予後予測, 渡邉 幹夫,井上 直哉,森田 麻美,巽 圭太,日高 洋,赤水 尚史,岩谷 良則, 日本内分泌学会雑誌, (一社)日本内分泌学会, Vol. 87, No. 2, p. 509-509, 2011/09
  • DNMT1、3a、3b遺伝子の多型と自己免疫性甲状腺疾患の病態およびゲノムのメチル化率との関連, 荒川 裕也,渡邉 幹夫,井上 直哉,日高 洋,巽 圭太,岩谷 良則, 日本内分泌学会雑誌, (一社)日本内分泌学会, Vol. 87, No. 2, p. 536-536, 2011/09
  • ケモカイン遺伝子の機能的多型と自己免疫性甲状腺疾患の病態との関連, 赤羽 舞子,渡邉 幹夫,井上 直哉,日高 洋,巽 圭太,岩谷 良則, 日本内分泌学会雑誌, (一社)日本内分泌学会, Vol. 87, No. 2, p. 537-537, 2011/09
  • 自己免疫性甲状腺疾患の病態予後とIL-5、IL-6、IL-13遺伝子プロモータ領域の多型との関連, 渡邉 幹夫,井上 直哉,森田 麻美,巽 圭太,日高 洋,赤水 尚史,岩谷 良則, 日本臨床免疫学会会誌, 日本臨床免疫学会, Vol. 34, No. 4, p. 290-290, 2011/08
  • IL-5、IL-6、IL-13遺伝子プロモータ領域の多型と自己免疫性甲状腺疾患の病態予後との関連, 渡邉 幹夫,井上 直哉,森田 麻美,巽 圭太,日高 洋,赤水 尚史,岩谷 良則, 日本遺伝カウンセリング学会誌, 日本遺伝カウンセリング学会, Vol. 32, No. 2, p. 75-75, 2011/05
  • IL-5、IL-6、IL-13遺伝子プロモータ領域の多型と自己免疫性甲状腺疾患の病態予後との関連, 渡邉 幹夫,井上 直哉,森田 麻美,巽 圭太,日高 洋,赤水 尚史,岩谷 良則, 家族性腫瘍, 日本家族性腫瘍学会, Vol. 11, No. 2, p. A75-A75, 2011/05
  • Association of functional polymorphisms in promoter regions of IL5, IL6 and IL13 genes with development and prognosis of autoimmune thyroid diseases, N. Inoue,M. Watanabe,M. Morita,K. Tatusmi,Y. Hidaka,T. Akamizu,Y. Iwatani, CLINICAL AND EXPERIMENTAL IMMUNOLOGY, WILEY, Vol. 163, No. 3, p. 318-323, 2011/03
  • Association of functional polymorphisms in promoter regions of IL5, IL6, and IL13 genes with development and prognosis of autoimmune thyroid diseases., Naoya Inoue,Mikio Watanabe,Mami Morita,Ke-ita Tatsumi,Yoh Hidaka,Takashi Akamizu,Yoshinori Iwatani, Clinical and Experimental Immunology, WILEY, Vol. 163, No. 3, p. 318-323, 2011/03
  • 臨床検査技師にこそ情報教育を!(臨床検査技師教育機関からの声), Vol. 第265巻7ページ, 2011/02
  • 自己免疫性甲状腺疾患の病態予後とIL5, I-6, IL13遺伝子プロモータ領域の多型との関連, Vol. 39, No. 0, p. 104-104, 2011
  • Association of functional polymorphisms related to the transcriptional level of FOXP3 with prognosis of autoimmune thyroid diseases., Naoya Inoue,Mikio Watanabe,Mami Morita,Rie Tomizawa,Takashi Akamizu,Ke-ita Tatsumi,Yoh Hidaka,Yoshinori Iwatani, Clinical and Experimental Immunology, WILEY-BLACKWELL, Vol. 162, No. 3, p. 402-406, 2010/12
  • Association of functional polymorphisms related to the transcriptional level of FOXP3 with prognosis of autoimmune thyroid diseases, N. Inoue,M. Watanabe,M. Morita,R. Tomizawa,T. Akamizu,K. Tatsumi,Y. Hidaka,Y. Iwatani, CLINICAL AND EXPERIMENTAL IMMUNOLOGY, WILEY-BLACKWELL, Vol. 162, No. 3, p. 402-406, 2010/12
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  • Messenger RNA Quantification After Fluorescence-Activated Cell Sorting Using In Situ Hybridization, Hiroya Yamada,Rie Maruo,Mikio Watanabe,Yoh Hidaka,Yoshinori Iwatani,Toru Takano, CYTOMETRY PART A, WILEY-BLACKWELL, Vol. 77A, No. 11, p. 1032-1037, 2010/11
  • Messenger RNA Quantification After Fluorescence-Activated Cell Sorting Using In Situ Hybridization, Hiroya Yamada,Rie Maruo,Mikio Watanabe,Yoh Hidaka,Yoshinori Iwatani,Toru Takano, CYTOMETRY PART A, WILEY-BLACKWELL, Vol. 77A, No. 11, p. 1032-1037, 2010/11
  • 自己免疫性甲状腺疾患の予後にFOXP3発現の個体差が及ぼす影響, 渡邉 幹夫,井上 直哉,森田 麻美,富澤 理恵,赤水 尚史,巽 圭太,日高 洋,岩谷 良則, 日本内分泌学会雑誌, (一社)日本内分泌学会, Vol. 86, No. 2, p. 262-262, 2010/09
  • 自己免疫性甲状腺疾患(AITD)の難治性および重症度とTBX21遺伝子多型との関連, 森田 麻美,渡邉 幹夫,稲岡 知紗,井上 直哉,赤水 尚史,巽 圭太,日高 洋,岩谷 良則, 日本内分泌学会雑誌, (一社)日本内分泌学会, Vol. 86, No. 2, p. 281-281, 2010/09
  • Increases in urinary creatinine and blood pressure during early pregnancy in preeclampsia, Kouichi Kuromoto,Mikio Watanabe,Kazushige Adachi,Kazutomo Ohashi,Yoshinori Iwatani, Annals of Clinical Biochemistry, SAGE PUBLICATIONS INC, Vol. 47, p. 336-342, 2010/08
  • Increases in urinary creatinine and blood pressure during early pregnancy in preeclampsia, Kouichi Kuromoto,Mikio Watanabe,Kazushige Adachi,Kazutomo Ohashi,Yoshinori Iwatani, Annals of Clinical Biochemistry, SAGE PUBLICATIONS INC, Vol. 47, p. 336-342, 2010/08
  • 自己免疫性甲状腺疾患の難治性および重症度とTBX21遺伝子多型との関連, 森田 麻美,井上 直哉,渡邉 幹夫,日高 洋,巽 圭太,赤水 尚史,岩谷 良則, 臨床病理, 日本臨床検査医学会, Vol. 58, No. 補冊, p. 140-140, 2010/07
  • FOXP3遺伝子の個体差と自己免疫性甲状腺疾患の病態予後との関連, 井上 直哉,渡邉 幹夫,森田 麻美,冨澤 理恵,日高 洋,巽 圭太,林 貞夫,赤水 尚史,岩谷 良則, 臨床病理, 日本臨床検査医学会, Vol. 58, No. 補冊, p. 141-141, 2010/07
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  • Messenger RNA quantification after fluorescence activated cell sorting using intracellular antigens., Hiroya Yamada,Rie Maruo,Mikio Watanabe,Yoh Hidaka,Yoshinori Iwatani,toru Takano, Biochemical and Biophysical Research Communications, ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 397, No. 3, p. 425-428, 2010/06
  • Messenger RNA quantification after fluorescence activated cell sorting using intracellular antigens., Hiroya Yamada,Rie Maruo,Mikio Watanabe,Yoh Hidaka,Yoshinori Iwatani,toru Takano, Biochemical and Biophysical Research Communications, Vol. in press, 2010/06
  • Preoperative diagnosis of thyroid nodules by measuresing TFF3/LGALS3 mRNA (T/G) ratio: A clinical trial of fifty cases, Hiroya Yamada,Toru Takano,Minoru Kihara,Mitsuyoshi Hirokawa,Hiroshi Yoshida,Mikio Watanabe,Yoshinori Iwatani,Yoh Hidaka,Akira Miyauchi, ENDOCRINE JOURNAL, JAPAN ENDOCRINE SOC, Vol. 57, p. S462-S462, 2010/03
  • 第4回日本臨床検査学教育学会学術大会イブニングセミナー(遺伝子検査学), Vol. 38(3), 2010/03
  • Postpartum increase of serum thioredoxin concentrations and the relation to CD8 lymphocytes., Shoko Kuroda,Mikio Watanabe,Tomoko Santo,Yu Shimizuishi,Toru Takano,Yoh Hidaka,Tadashi Kimura,Yoshinori Iwatani, Annals of Clinical Biochemistry, ROYAL SOC MEDICINE PRESS LTD, Vol. 47, p. 62-66, 2010/01
  • Drug selection and Laboratory tests -Graves' disease-, The Yakuji Nippo Medical, Vol. No.10794, page m8, 2010
  • Postpartum increase of serum thioredoxin concentrations and the relation to CD8 lymphocytes, Shoko Kuroda,Mikio Watanabe,Tomoko Santo,Yu Shimizuishi,Toru Takano,Yoh Hidaka,Tadashi Kimura,Yoshinori Iwatani, ANNALS OF CLINICAL BIOCHEMISTRY, ROYAL SOC MEDICINE PRESS LTD, Vol. 47, p. 62-66, 2010/01
  • 検査値と薬剤選択―バセドウ病―, Vol. No.10794, page m8, 2010
  • Association of the-31C/T functional polymorphism in the interleukin-1 beta gene with the intractability of Graves&apos; disease and the proportion of T helper type 17 cells, F. Hayashi,M. Watanabe,T. Nanba,N. Inoue,T. Akamizu,Y. Iwatani, CLINICAL AND EXPERIMENTAL IMMUNOLOGY, WILEY-BLACKWELL PUBLISHING, INC, Vol. 158, No. 3, p. 281-286, 2009/12
  • Association of the-31C/T functional polymorphism in the interleukin-1 beta gene with the intractability of Graves&apos; disease and the proportion of T helper type 17 cells, F. Hayashi,M. Watanabe,T. Nanba,N. Inoue,T. Akamizu,Y. Iwatani, CLINICAL AND EXPERIMENTAL IMMUNOLOGY, WILEY-BLACKWELL PUBLISHING, INC, Vol. 158, No. 3, p. 281-286, 2009/12
  • ヒト免疫病におけるTh17細胞とTreg細胞 IL1B遺伝子-31C/T多型がバセドウ病の難治性とTh17細胞比率に及ぼす影響, 渡邉 幹夫,林 文明,南波 崇,井上 直哉,赤水 尚史,岩谷 良則, 日本臨床免疫学会会誌, 日本臨床免疫学会, Vol. 32, No. 5, p. 361-361, 2009/10
  • Early Detection of Colorectal Cancer Metastasis and Relapse by Recognizing Nonspecific Cross-Reacting Antigen 2 in Commercial Carcinoembryonic Antigen Assays, Hiroyuki Hanada,Satami Mugii,Keiko Takeoka,Ikuhiro Maeda,Mikio Watanabe,Yoh Hidaka,Yoshiori Iwatani, CLINICAL CHEMISTRY, AMER ASSOC CLINICAL CHEMISTRY, Vol. 55, No. 9, p. 1747-1748, 2009/09
  • バセドウ病の難治性とTh17細胞比率に及ぼすIL1β遺伝子-31C/T機能的多型の影響, 渡邉 幹夫,林 文明,南波 崇,井上 直哉,赤水 尚史,岩谷 良則, 日本内分泌学会雑誌, (一社)日本内分泌学会, Vol. 85, No. 2, p. 492-492, 2009/09
  • Association of the -31C/T functional polymorphism in the interleukin-1β gene with the intractability of Graves' disease and the proportion of Th17 cells., Watanabe, M,Hayashi, F,Nanba, T,Inoue, N,Akamizu, T,Iwatani, Y, Clinical and Experimental Immunology, 2009/09
  • Early detection of metastasis and relapse of colorectal cancer by recognizing NCA-2 in commercially available CEA assay., Hiroyuki Hanada,Satomi Mugii,Keiko Takeoka,Ikuhiro Maeda,Mikio Watanabe,Yoh Hidaka,Yoshinori Iwatani, Clinical Chemistry, Vol. 55, No. 9, p. 1747-1751, 2009/09
  • TNF-α遺伝子多型と自己免疫性甲状腺疾患の病態との関連, 井上 直哉,渡邉 幹夫,南波 崇,赤水 尚史,岩谷 良則, 臨床病理, 日本臨床検査医学会, Vol. 57, No. 補冊, p. 203-203, 2009/07
  • 難治性バセドウ病患者でのIL1B遺伝子-31Tアリル頻度の増加, 渡邉 幹夫,林 文明,南波 崇,井上 直哉,赤水 尚史,岩谷 良則, 臨床化学, (一社)日本臨床化学会, Vol. 38, No. Suppl.1, p. 120-120, 2009/07
  • Increases of the Th1/Th2 cell ratio in severe Hashimoto's disease and in the proportion of Th17 cells in intractable Graves' disease., Takashi Nanba,Mikio Watanabe,Naoya Inoue,Yoshinori Iwatani, Thyroid, Vol. 19(5), 495-501, 2009/05
  • Involvement of functional polymorphisms in the TNFA gene in the pathogenesis of autoimmune thyroid diseases and production of anti-thyrotropin receptor antibody, N. Inoue,M. Watanabe,T. Nanba,M. Wada,T. Akamizu,Y. Iwatani, CLINICAL AND EXPERIMENTAL IMMUNOLOGY, WILEY-BLACKWELL PUBLISHING, INC, Vol. 156, No. 2, p. 199-204, 2009/05
  • Increases of the Th1/Th2 Cell Ratio in Severe Hashimoto&apos;s Disease and in the Proportion of Th17 Cells in Intractable Graves&apos; Disease, Takashi Nanba,Mikio Watanabe,Naoya Inoue,Yoshinori Iwatani, THYROID, MARY ANN LIEBERT INC, Vol. 19, No. 5, p. 495-501, 2009/05
  • Involvement of functional polymorphisms in the TNFA gene in the pathogenesis of autoimmune thyroid diseases and production of anti-TSH receptor antibody., Naoya Inoue,Mikio Watanabe,Takashi Nanba,Megumi Wada,Takashi Akamizu,Yoshinori Iwatani, Clinical and Experimental Immunology, WILEY-BLACKWELL PUBLISHING, INC, Vol. 156, No. 2, p. 199-204, 2009/05
  • 自己免疫性甲状腺疾患の難治性および重症度とIL-12/IL-12R遺伝子多型との関連, 井上 直哉,中口 あづさ,上田 大史,渡邉 幹夫,赤水 尚史,岩谷 良則, 日本内分泌学会雑誌, (一社)日本内分泌学会, Vol. 85, No. 1, p. 360-360, 2009/04
  • Expression of nestin mRNA is a differentiation marker in thyroid tumors., Hiroya Yamada,Toru Takano,Yasuhiro Ito,Fumio Matsuzuka,Akihiro Miya,Kaoru Kobayashi,Hiroshi Yoshida,Mikio Watanabe,Yoshinori Iwatani,Akira Miyauchi, Cancer Letters, ELSEVIER IRELAND LTD, Vol. 280, No. 1, p. 61-64, 2009/04
  • Expression of nestin mRNA is a differentiation marker in thyroid tumors., Hiroya Yamada,Toru Takano,Yasuhiro Ito,Fumio Matsuzuka,Akihiro Miya,Kaoru Kobayashi,Hiroshi Yoshida,Mikio Watanabe,Yoshinori Iwatani,Akira Miyauchi, Cancer Letters, ELSEVIER IRELAND LTD, Vol. 280, No. 1, p. 61-64, 2009/04
  • <I>IL1B</I>遺伝子-31C/T多型がバセドウ病の難治性とTh17細胞比率に及ぼす影響, Vol. 37, No. 0, p. 81-81, 2009
  • Thyroid diseases during and after pregnancy, Sogo Rinsho, Vol. 58 (7), 1587-1591, 2009
  • Report from Academic Meeting -- The Japanese Society for Gene Diagnosis and Therapy, Japanese Journal of Medical Technology Education, Vol. 1(2), 162-164, 2009
  • Association of the -31C/T functional polymorphism in the interleukin-1β gene with the intractability of Graves' disease and the proportion of Th17 cells., 2009
  • Early detection of metastasis and relapse of colorectal cancer by recognizing NCA-2 in commercially available CEA assay., Clinical Chemistry, Vol. in press, 2009
  • Clinical utility and characteristics of nine anti-HCV antibody screening reagents used in Japan., Kita,M,Deguchi, M,Kagita,M,Yoshioka, N,Kobayashi, E,Watanabe, M,Asari, S,Yamanaka, K,Iwatani, Y, Clinical Laboratory, CLIN LAB PUBL, Vol. 55, No. 1-2, p. 9-22, 2009/01
  • 妊娠・出産と甲状腺疾患, Vol. 58 (7), 1587-1591, 2009
  • 関連学会報告―日本遺伝子診療学会, Vol. 1(2), 162-164, 2009
  • Clinical utility and characteristics of nine anti-HCV antibody screening reagents used in Japan., Kita,M,Deguchi, M,Kagita,M,Yoshioka, N,Kobayashi, E,Watanabe, M,Asari, S,Yamanaka, K,Iwatani, Y, Clinical Laboratory, CLIN LAB PUBL, Vol. 55, No. 1-2, p. 9-22, 2009/01
  • 自己免疫性甲状腺疾患の難治性・重症度とInterleukin 1β-31C/T遺伝子多型との関連, 林 文明,渡邉 幹夫,井上 直哉,赤水 尚史,岩谷 良則, 臨床病理, 日本臨床検査医学会, Vol. 56, No. 補冊, p. 144-144, 2008/10
  • 重症橋本病における末梢Th1/Th2細胞数比の増加と難治性バセドウ病における末梢Th17細胞比率の増加, 渡邉 幹夫,南波 崇,井上 直哉,岩谷 良則, 臨床病理, 日本臨床検査医学会, Vol. 56, No. 補冊, p. 144-144, 2008/10
  • Patients of Hashimto's disease with -599CC genotype in the IL4 gene would develop hypothyroidis, Mikio Watanabe,Takashi Nanba,Takashi Akamizu,Yoshinori Iwatani, 2008/10
  • 甲状腺破壊が高度な橋本病におけるTh1/Th2細胞数比の増加と難治性バセドウ病におけるTh17細胞の増加, 渡邉 幹夫,南波 崇,井上 直哉,岩谷 良則, 日本内分泌学会雑誌, (一社)日本内分泌学会, Vol. 84, No. 2, p. 430-430, 2008/09
  • 難治性バセドウ病におけるTh17細胞の増加と重症橋本病におけるTh1/Th2比の増加, 渡邉 幹夫,南波 崇,井上 直哉,岩谷 良則, 日本臨床免疫学会会誌, 日本臨床免疫学会, Vol. 36, No. 0, p. 165-165, 2008/08
  • A Novel microfluidic immunoassay to determine AFP-L3% in serum samples., Hanada, H,Kagebayashi, C,Kurosawa, T,Kawabata, T,Kitano, H,Li, C,Bousse, L,Watanabe, M,Maeda, I,Takeoka, K,Watanabe, M,Wada, H. G,Hidaka, Y,Iwatani, Y,Satomura, S, CLINICAL CHEMISTRY, AMER ASSOC CLINICAL CHEMISTRY, Vol. 54, No. 6, p. A203-A203, 2008/07
  • A Novel microfluidic immunoassay to determine AFP-L3% in serum samples., Hanada, H,Kagebayashi, C,Kurosawa, T,Kawabata, T,Kitano, H,Li, C,Bousse, L,Watanabe, M,Maeda, I,Takeoka, K,Watanabe, M,Wada, H. G,Hidaka, Y,Iwatani, Y,Satomura, S, 2008/07
  • A new predictive indicator for development of pressure ulcer in bedridden patients based on common laboratory tests results, Hatanaka, N,Yamamoto, Y,Ichihara, K,Sato, A,Chihara, K,Nakamura, Y,Watanabe, M,Iwatani, Y, Journal of Clinical Pathology, B M J PUBLISHING GROUP, Vol. 61, No. 4, p. 514-518, 2008/04
  • A new predictive indicator for development of pressure ulcers in bedridden patients based on common laboratory tests results, N. Hatanaka,Y. Yamamoto,K. Ichihara,S. Mastuo,Y. Nakamura,M. Watanabe,Y. Iwatani, JOURNAL OF CLINICAL PATHOLOGY, B M J PUBLISHING GROUP, Vol. 61, No. 4, p. 514-518, 2008/04
  • The 869T/C polymorphism in the transforming growth factor-beta1 gene is associated with the severity and intractability of autoimmune thyroid disease., Yamada, H,Watanabe, M,Nanba, T,Akamizu, T,Iwatani, Y, Clinical and Experimental Immunology, BLACKWELL PUBLISHING, Vol. 151, No. 3, p. 379-382, 2008/03
  • The-590CC genotype in the IL4 gene as a strong predictive factor for the development of hypothyroidism in Hashimoto disease, Takashi Nanba,Mikio Watanabe,Takashi Akamizu,Yoshinori Iwatani, CLINICAL CHEMISTRY, AMER ASSOC CLINICAL CHEMISTRY, Vol. 54, No. 3, p. 621-623, 2008/03
  • The 869T/C polymorphism in the transforming growth factor-beta1 gene is associated with the severity and intractability of autoimmune thyroid disease., Yamada, H,Watanabe, M,Nanba, T,Akamizu, T,Iwatani, Y, Clinical and Experimental Immunology, BLACKWELL PUBLISHING, Vol. 151, No. 3, p. 379-382, 2008/03
  • The -590CC Genotype in Interleukin-4 Gene as a Strong Predictive Factor for the Development of Hypothyroidism in Hashimoto's Disease, Takashi Nanba,Mikio Watanabe,Takashi Akamizu,Yoshinori Iwatani, Clinical Chemistry, Vol. 54(3), 621-623, 2008/03
  • 5種のHIVスクリーニング検査試薬の評価, Vol. 33(2), 183-189, 2008/02
  • Patients of Hashimto's disease with -599CC genotype in the IL4 gene would develop hypothyroidis, 2008
  • Laboratory tests viewed in symptom - Weight loss -, The YAKUJI NIPPO MEDICAL, Vol. No.10609, page m8, 2008
  • Decrease of intrathyroidal CD161+Vα24+Vβ 11+ NKT cells in Graves' disease, Mikio Watanabe,Yukiyo Nakamura,Fumio Matsuzuka,Yuuki Takamura,Akira Miyauchi,Yoshinori Iwatani, Endocrine Journal, Vol. 55, No. 1, p. 199-203, 2008
  • 6種類のTreponema Pallidum(TP)抗体測定法の比較, Vol. 33(1), 26-31, 2008/01
  • 症状から見た臨床検査―体重減少―, Vol. No.10609, page m8, 2008
  • Decrease of intrathyroidal CD161+Vα24+Vβ 11+ NKT cells in Graves' disease, Mikio Watanabe,Yukiyo Nakamura,Fumio Matsuzuka,Yuuki Takamura,Akira Miyauchi,Yoshinori Iwatani, Endocrine Journal, Vol. 55, No. 1, p. 199-203, 2008
  • Clinical significance of CEA-family measurement as a marker for metastasis and relapse of cancer., Hanada, H,Takeoka, K,Nomura, T,Yamashita, Y,Namba, T,Watanabe, M,Iwatani Y,Hidaka, Y, CLINICAL CHEMISTRY, AMER ASSOC CLINICAL CHEMISTRY, Vol. 53, No. 6, p. A105-A105, 2007/07
  • Clinical significance of CEA-family measurement as a marker for metastasis and relapse of cancer., Hanada, H,Takeoka, K,Nomura, T,Yamashita, Y,Namba, T,Watanabe, M,Iwatani Y,Hidaka, Y, CLINICAL CHEMISTRY, AMER ASSOC CLINICAL CHEMISTRY, Vol. 53, No. 6, p. A105-A105, 2007/07
  • 化学発光酵素免疫測定法によるHCV core抗原測定法の評価, Vol. 32(5), 817-820, 2007/05
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  • Apoptosis-induced decrease of intrathyroidal CD4(+)CD25(+) regulatory T cells in autoimmune thyroid diseases, Aiko Nakano,Mikio Watanabe,Takao Iida,Shoko Kuroda,Fumio Matsuzuka,Akira Miyauchi,Yoshinori Iwatani, THYROID, MARY ANN LIEBERT INC, Vol. 17, No. 1, p. 25-31, 2007/01
  • 化学発光免疫測定試薬「アーキテクトHBe AgおよびHBe Ab」の基本性能と臨床的有用性, Vol. 32(1), 63-68, 2007/01
  • Apoptosis induced decrease of intrathyroidal CD4+CD25+ regulatory T cells in autoimmune thyroid diseases, Aiko Nakano,Mikio Watanabe,Takao Iida,Shoko Kuroda,Fumio Matsuzuka,Akira Miyauchi,Yoshinori Iwatani, Thyroid, MARY ANN LIEBERT INC, Vol. 17, No. 1, p. 25-31, 2007/01
  • HCV抗体測定における3種化学発光法の比較, Vol. 31(5), 833-837, 2006/11
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  • Association between the severity of Hashimoto's disease and the functional +874A/T polymorphism in the interferon-gamma gene, Chisato Ito,Mikio Watanabe,Noriko Okuda,Chikami Watanabe,Yoshinori Iwatani, ENDOCRINE JOURNAL, JAPAN ENDOCRINE SOCIETY, Vol. 53, No. 4, p. 473-478, 2006/08
  • Association between the severity of Hashimoto's disease and the functional +874A/T polymorphism in the interferon-gamma gene, Chisato Ito,Mikio Watanabe,Noriko Okuda,Chikami Watanabe,Yoshinori Iwatani, ENDOCRINE JOURNAL, JAPAN ENDOCRINE SOCIETY, Vol. 53, No. 4, p. 473-478, 2006/08
  • Association between the severity of Hashimoto's disease and the functional +874A/T polymorphism in the interferon-gamma gene, Chisato Ito,Mikio Watanabe,Noriko Okuda,Chikami Watanabe,Yoshinori Iwatani, ENDOCRINE JOURNAL, JAPAN ENDOCRINE SOCIETY, Vol. 53, No. 4, p. 473-478, 2006/08
  • Chemiluminescent Enzyme Immunoassay (CLEIA)による風疹ウィルス抗体測定の基礎的検討, Vol. 31(2), 228-233, 2006, 2006/02
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  • Association between the severity of Hashimoto's disease and the functional +874A/T polymorphism in the interferon-γ gene, Chisato Ito,Mikio Watanabe,Noriko Okuda,Chikami Watanabe,Yoshinori Iwatani, Endocrine Journal, Vol. 53, No. 4, p. 473-478, 2006
  • A useful new classification of dysmorphic urinary erythrocytes, Daisuke Nagahama,Kenichi Yoshiko,Mikio Watanabe,Yoshiki Morita,Yoshinori Iwatani,Seiichi Matsuo, Clinical and Experimental Nephrology, Vol. 9, No. 4, p. 304-309, 2005/12
  • Association between the severity of Hashimoto's disease and the functional +874A/T polymorphism in the interferon-gamma gene., Chisato Ito,Mikio Watanabe,Noriko Okuda,Chikami Watanabe,Yoshinori Iwatani, 2005/10
  • Association between the severity of Hashimoto's disease and the functional +874A/T polymorphism in the interferon-gamma gene., Chisato Ito,Mikio Watanabe,Noriko Okuda,Chikami Watanabe,Yoshinori Iwatani, 2005/10
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  • 最新医学大辞典, 2005
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  • 最新医学大辞典, 2005
  • A useful new classification of dysmorphic urinary erythrocytes., Vol. 9(4):304-9., 2005
  • Intrathyroidal CD4(+) T lymphocytes express high levels of Fas and CD4(+)CD8(+) macrophages/dendritic cells express fas ligand in autoimmune thyroid disease, Y Nakamura,M Watanabe,F Matsuzuka,H Maruoka,A Miyauchi,Y Iwatani, THYROID, MARY ANN LIEBERT INC, Vol. 14, No. 10, p. 819-824, 2004/10
  • Intrathyroidal CD4+ T lymphocytes express high levels of Fas and CD4+CD8+ macrophages / dendritic cells express Fas ligand in autoimmune thyroid disease, Nakamura Y,Watanabe M,Matsuzuka F,Miyauchi A,Iwatani Y, Thyroid, MARY ANN LIEBERT INC, Vol. 14, No. 10, p. 819-824, 2004/10
  • Lower concentration of serum soluble CD8 in severe Hashimoto's disease, N Yamamoto,M Watanabe,F Matsuzuka,A Miyauchi,Y Iwatani, CLINICAL AND EXPERIMENTAL IMMUNOLOGY, BLACKWELL PUBLISHING LTD, Vol. 137, No. 3, p. 601-605, 2004/09
  • Lower concentration of serum soluble CD8 in severe Hashimoto's disease., Yamamoto, N,Watanabe, M,Matsuzuka, F,Miyauchi, A,Iwatani, Y, Clin Exp Immunol, BLACKWELL PUBLISHING LTD, Vol. 137, No. 3, p. 601-605, 2004/08
  • Effects of plant's aroma on anti-stress with Plant's leaf tearing task., Iwasaki, Y,Yamamoto, S,Kweon, H,Watanabe, M,Asano, F, 2004/06
  • Increased intensities of fas expression on peripheral T-cell subsets in severe autoimmune thyroid disease, H Maruoka,M Watanabe,F Matsuzuka,T Takimoto,A Miyauchi,Y Iwatani, THYROID, MARY ANN LIEBERT, INC, Vol. 14, No. 6, p. 417-423, 2004/06
  • Decrease of CD154 intensity on peripheral CD4(+) T cells in autoimmune thyroid disease, M Watanabe,N Yamamoto,F Matsuzuka,A Miyauchi,Y Iwatani, CLINICAL AND EXPERIMENTAL IMMUNOLOGY, BLACKWELL PUBLISHING LTD, Vol. 136, No. 3, p. 555-558, 2004/06
  • Effects of plant's aroma on anti-stress with Plant's leaf tearing task., Iwasaki, Y,Yamamoto, S,Kweon, H,Watanabe, M,Asano, F, 2004/06
  • Increased intensities of Fas expression on peripheral T cell subsets in severe autoimmune thyroid disease., Maruoka, H,Watanabe, M,Matsuzuka, F,Takimoto, T,Miyauchi, A,Iwatani, Y, Thyroid, MARY ANN LIEBERT, INC, Vol. 14, No. 6, p. 417-423, 2004/06
  • Decrease of CD154 intensity on peripheral CD4+ T cells in autoimmune thyroid disease, Watanabe, M,Yamamoto, N,Matsuzuka, F,Miyauchi, A,Iwatani, Y, Clin Exp Immunol, BLACKWELL PUBLISHING LTD, Vol. 136, No. 3, p. 555-558, 2004/06
  • Study on stress easing effect by aroma of revegetation trees in city, AROMA RESEARCH, 2004
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  • Physiological changes of Fas expression in peripheral lymphocyte subsets during the menstrual cycle, R Shinoda,M Watanabe,Y Nakamura,H Maruoka,Y Kimura,Y Iwatani, JOURNAL OF REPRODUCTIVE IMMUNOLOGY, ELSEVIER SCI IRELAND LTD, Vol. 60, No. 2, p. 159-168, 2003/12
  • Basic study on human psychological and physiological characteristics in responses to existing plants in urban parks., Yamamoto, S,Iwasaki, Y,Mino, N,Watanabe, M, Journal of the Japanese Institute of Landscape Architecture, International Edition, 2, 25-30, 2003, Vol. 2, 25-30/,, 2003/10
  • Basic study on human psychological and physiological characteristics in responses to existing plants in urban parks., Yamamoto, S,Iwasaki, Y,Mino, N,Watanabe, M, Journal of the Japanese Institute of Landscape Architecture, International Edition, 2, 25-30, 2003, Vol. 2, 25-30/,, 2003/10
  • Physiological changes of Fas expression in peripheral lymphocyte subsets during the menstrual cycle., Shinoda, R,Watanabe, M,Nakamura, Y,Maruoka, H,Kimura, Y,Iwatani, Y, J Reprod Immunol, ELSEVIER SCI IRELAND LTD, Vol. 60, No. 2, p. 159-168, 2003/10
  • High frequency of antibiotic-associated diarrhea due to toxin A-negative, toxin B-positive Clostridium difficile in a hospital in Japan and risk factors for infection, M Komatsu,H Kato,M Aihara,K Shimakawa,M Iwasaki,Y Nagasaka,S Fukuda,S Matsuo,Y Arakawa,M Watanabe,Y Iwatani, EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, SPRINGER-VERLAG, Vol. 22, No. 9, p. 525-529, 2003/09
  • High Frequency of Antibiotic-Associated Diarrhea due to Toxin A-Negative, Toxin B-Positive Clostridium difficile in a Hospital in Japan and Risk Factors for Infection., Komatsu, M,Kato, H,Aihara, M,Shimakawa, K,Iwasaki, M,Nagasaka, Y,Fukuda, S,Matsuo, S,Arakawa, Y,Watanabe, M,Iwatani, Y, Eur J Clin Microbiol Infect, SPRINGER-VERLAG, Vol. 22, No. 9, p. 525-529, 2003/08
  • Seroprevalence survey of measles, rubella, varicella, and mumps antibodies in health care workers and evaluation of a vaccination program in a tertiary care hospital in Japan, S Asari,M Deguchi,K Tahara,M Taniike,M Toyokawa,Nishi, I,M Watanabe,Y Iwatani,K Makimoto, AMERICAN JOURNAL OF INFECTION CONTROL, MOSBY, INC, Vol. 31, No. 3, p. 157-162, 2003/05
  • Increase in immunoglobulin G3-secreting cells in intractable Graves' disease, Y Nakamoto,M Niki,M Watanabe,Y Iwatani, THYROID, MARY ANN LIEBERT INC PUBL, Vol. 13, No. 4, p. 325-331, 2003/04
  • Increase in Immunoglobulin G3-Secreting Cells in Intractable Graves' Disease, Yumi Nakamoto,Makoto Niki,Mikio Watanabe,Yoshinori Iwatani, Thyroid, MARY ANN LIEBERT INC PUBL, Vol. 13, No. 4, p. 325-331, 2003/04
  • Seroprevalence Survey Of Measles, Rubella, Varicella, And Mumps Antibodies In Health Care Workers And Evaluation Of Vaccination Program In A Tertiary Care Hospital In Japan, Seishi Asari,Matsuo Deguchi,Kazuko Tahara,Masako Taniike,Masahiro Toyokawa,Isao Nishi,Mikio Watanabe,Yoshinori Iwatani,Kiyoko Makimoto, Am J Infect Control Vol.31, p.157-162, MOSBY, INC, Vol. 31, No. 3, p. 157-162, 2003/03
  • Relation Of CD30 Molecules On T Cell Subsets To The Severity Of Autoimmune Thyroid Disease, Mikio Watanabe,Naoko Yamamoto,Hayato Maruoka,Fumio Matsuzuka,Akira Miyauchi,Yoshinori Iwatani, Thyroid, Vol. in press, 2003/03
  • Relation of CD30 molecules on T-cell subsets to the severity of autoimmune thyroid disease, Mikio Watanabe,Naoko Yamamoto,Hayato Maruoka,Fumio Matsuzuka,Akira Miyauchi,Yoshinori Iwatani, Thyroid, Mary Ann Liebert Inc., Vol. 13, No. 3, p. 259-263, 2003/03/01
  • 高齢者に若年者の臨床検査正常値をそのままあてはめてはいけない!, Vol. 85, 222-224/,, 2003
  • 都市公園の植栽デザインの違いによる人間の心理的・生理的反応特性に関する基礎的研究, 2003
  • Independent involvement of CD8+CD25+ cells and thyroid autoantibodies in disease severity of Hashimoto's disease., Mikio Watanabe,Naoko Yamamoto,Hayato Maruoka,Hajime Tamai,Fumio Matsuzuka,Akira Miyauchi,Yoshinori Iwatani, THYROID, MARY ANN LIEBERT INC PUBL, Vol. 12, No. 9, p. 801-808, 2002/10
  • Independent involvement of CD8(+)CD25(+) cells and thyroid autoantibodies in disease severity of Hashimoto's disease, M Watanabe,N Yamamoto,H Maruoka,H Tamai,F Matsuzuka,A Miyauchi,Y Iwatani, THYROID, MARY ANN LIEBERT INC PUBL, Vol. 12, No. 9, p. 801-808, 2002/09
  • Independent involvement of CD8(+)CD25(+) cells and thyroid autoantibodies in disease severity of Hashimoto's disease, M Watanabe,N Yamamoto,H Maruoka,H Tamai,F Matsuzuka,A Miyauchi,Y Iwatani, THYROID, MARY ANN LIEBERT INC PUBL, Vol. 12, No. 9, p. 801-808, 2002/09
  • Independent involvement of CD8(+)CD25(+) cells and thyroid autoantibodies in disease severity of Hashimoto's disease, M Watanabe,N Yamamoto,H Maruoka,H Tamai,F Matsuzuka,A Miyauchi,Y Iwatani, THYROID, MARY ANN LIEBERT INC PUBL, Vol. 12, No. 9, p. 801-808, 2002/09
  • 甲状腺中毒症とそのみかた (診断の指針・治療の指針), Vol. 51(8), 2485-2486/,, 2002
  • 慢性甲状腺炎(橋本病)の発症とT細胞・自己抗体(特集「病変形成と免疫系」), Vol. 37, 656-663/,, 2002
  • Increase of CD5(+) B cells during adolescence in female mice, K Watanabe,M Watanabe,H Maruoka,N Amino,Y Iwatani, MECHANISMS OF AGEING AND DEVELOPMENT, ELSEVIER SCI IRELAND LTD, Vol. 122, No. 15, p. 1787-1795, 2001/10
  • Increase of CD5+ B cells during adolescence in female mice, Kiyoshi Watanabe,Mikio Watanabe,Hayato Maruoka,Nobuyuki Amino,Yoshinori Iwatani, Mechanisms of Ageing and Development, Vol. 122, No. 15, p. 1787-1795, 2001
  • Increased intensity of Fas expression on peripheral T cell subsets in severe autoimmune thyroid disease., Mikio Watanabe,Hayato Maruoka,Naoko Yamamoto,Fumio Matsuzuka,Hajime Tamai,Takimoto, T,Kanji Kuma,Yoshinori Iwatani, 2000/10
  • Increased intensity of Fas expression on peripheral T cell subsets in severe autoimmune thyroid disease., Mikio Watanabe,Hayato Maruoka,Naoko Yamamoto,Fumio Matsuzuka,Hajime Tamai,Takimoto, T,Kanji Kuma,Yoshinori Iwatani, 2000/10
  • Atherosclerosis and CD40, Endocrinology & Diabetology, Vol. 9, No. 1, 1999
  • 動脈硬化とCD40(共著), Vol. 9, No. 1, 1999
  • The Maternal Immune System In Health And Diseases, Yoshinori Iwatani,Mikio Watanabe, Vol. 10, 453/,, 1998/12
  • Necessity of training for using computer Network with manner, Report of Education Center for Information Processing Osaka University, No. 15, 1998
  • The maternal immune system in health and disease, Yoshinori Iwatani,Mikio Watanabe, Current Opinion in Obstetrics and Gynecology, Vol. 10, No. 6, p. 453-458, 1998
  • ネットワークマナー教育の必要性, No. 15, 1998
  • リンパ球サブセット, Vol. 493-497, 1998
  • 遊離サイロキシン(FT4)、遊離トリヨードサイロニン(FT3), Vol. 327-329, 1998
  • Opposite changes in serum soluble CD8 in patients at the active stages of Graves' and Hashimoto's diseases, M Watanabe,N Amino,K Hochito,K Watanabe,K Kuma,Y Iwatani, THYROID, MARY ANN LIEBERT INC PUBL, Vol. 7, No. 5, p. 743-747, 1997/10
  • Opposite Changes In Serum Soluble CD8 In Patients At The Active Stages Of Graves' And Hashimoto's Diseases, Mikio Watanabe,Nobuyuki Amino,Kazunori Hochito,Kiyoshi Watanabe,Kanji Kuma,Yoshinori Iwatani, THYROID, MARY ANN LIEBERT INC PUBL, Vol. 7, No. 5, p. 743-747, 1997/10
  • Changes in T, B, and NK Lymphocyte Subsets During and After Normal Pregnancy, Mikio Watanabe,Yoshinori Iwatani,Tatsunari Kaneda,Yoh Hidaka,Nobuaki Mitsuda,Yasuhiko Morimoto,Nobuyuki Amino, AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY, American Journal of Reproductive Immunology, Vol. 37, No. 5, p. 368-377, 1997/06
  • Changes in T, B, and NK Lymphocyte Subsets During and After Normal Pregnancy, Mikio Watanabe,Yoshinori Iwatani,Tatsunari Kaneda,Yoh Hidaka,Nobuaki Mitsuda,Yasuhiko Morimoto,Nobuyuki Amino, AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY, American Journal of Reproductive Immunology, Vol. 37, No. 5, p. 368-377, 1997/06
  • Changes in soluble CD4 and CD8 proteins in healthy pregnant and postpartum women, M Watanabe,Y Iwatani,Y Hidaka,N Mitsuda,N Amino, AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY, WILEY-BLACKWELL, Vol. 36, No. 4, p. 220-227, 1996/10
  • Changes in soluble CD4 and CD8 proteins in healthy pregnant and postpartum women, Mikio Watanabe,Yoshinori Iwatani,Yoh Hidaka,Nobuaki Mitsuda,Nobuyuki Amino, American Journal of Reproductive Immunology, Blackwell Publishing Ltd, Vol. 36, No. 4, p. 220-227, 1996
  • LONG-TERM EFFECTS OF THYROID-HORMONE ON LYMPHOCYTE SUBSETS IN SPLEENS AND THYMUSES OF MICE, K WATANABE,Y IWATANI,Y HIDAKA,M WATANABE,N AMINO, ENDOCRINE JOURNAL, JAPAN ENDOCRINE SOCIETY, Vol. 42, No. 5, p. 661-668, 1995/10
  • EUTHYROID GRAVES-DISEASE SHOWING NO THYROID ABNORMALITIES EXCEPT POSITIVE THYROID-STIMULATING ANTIBODY (TSAB) - 2 CASE-REPORTS, M WATANABE,Y IWATANI,T KASHIWANI,T IIJIMA,T FUJIKADO,N AMINO, JOURNAL OF INTERNAL MEDICINE, BLACKWELL SCIENCE LTD, Vol. 238, No. 4, p. 379-384, 1995/10
  • LONG-TERM EFFECTS OF THYROID-HORMONE ON LYMPHOCYTE SUBSETS IN SPLEENS AND THYMUSES OF MICE, K WATANABE,Y IWATANI,Y HIDAKA,M WATANABE,N AMINO, ENDOCRINE JOURNAL, JAPAN ENDOCRINE SOCIETY, Vol. 42, No. 5, p. 661-668, 1995/10
  • EUTHYROID GRAVES-DISEASE SHOWING NO THYROID ABNORMALITIES EXCEPT POSITIVE THYROID-STIMULATING ANTIBODY (TSAB) - 2 CASE-REPORTS, M WATANABE,Y IWATANI,T KASHIWANI,T IIJIMA,T FUJIKADO,N AMINO, JOURNAL OF INTERNAL MEDICINE, BLACKWELL SCIENCE LTD, Vol. 238, No. 4, p. 379-384, 1995/10
  • 甲状腺刺激抗体のみに異常を認めたEuthyroid Graves' Diseaseの一例, Vol. 44(2), 409-413/,, 1995
  • ACTH系調節異常のみ残存した出産後発症の中枢性副腎機能低下症の一例, Vol. 44(5), 997-1000/,, 1995

Publications

  • Kanai's Manual of Clinical Laboratory Medicine (The 35th edition), WATANABE, Mikio, KANEHARA & CO., LTD., 2020/05
  • DNA and Histone Methylation as Cancer Targets (Cancer Drug Discovery and Development) - Chapter 2 - The molecular basis of DNA methylation., Isao Suetake,Mikio Watanabe,Kohei Takeshita,Saori Takahashi,Peter Carlton, Humana Press, ISBN:3319597841, 2017/09
  • 遺伝子検査学実習書(臨床検査学実習書シリーズ), 医歯薬出版株式会社, ISBN:9784263223253, 2010/06
  • 最新医学大辞典, 医歯薬出版株式会社, 2005/04
  • Normal mechanisms for self-tolerance. In : Autoimmunity in the endocrine system, Humana press Inc., 1999
  • Normal mechanisms for self-tolerance., Autoimmunity in the endocrine system. Humana press Inc., 1999
  • Autoimmune Endocrinopathies, Chapter 1: Normal Mechanisms for Self-Tolerance, Yoshinori Iwatani,Mikio Watanabe, Humana Press Inc., 1999/01
  • メーリングリスト利用の情報交換による動物実験の洗練, 日本動物実験代替法学会第11回大会要旨集, 1997/10
  • Refinement of animal experimentation using Mailing lists, Proceedings of the 11th Annual Meeting of the Japanese Society for Alternatiues to Animal Experiments, 1997

Works

  • Development of laboratory tests for preventive diagnosis of autoimmune diseases, 1999 - 2000
  • 自己免疫疾患の予後診断法の開発, 1999 - 2000
  • 一卵性双生児を対象とし後天的遺伝要因に着目した自己免疫疾患予後予測検査法の開発, 2009 -
  • 末梢性自己寛容誘導機序の改名に基づく自己免疫疾患の発症予知診断法の開発, 2008 -
  • 甲状腺疾患をモデルとした自己免疫疾患予後予測検査法の開発, 2004 -
  • 「緑地の有するストレス緩和・医療的効果を考慮に入れたランドスケープ計画に関する研究」, 2003 -
  • 「都市公園の植栽デザインの違いによる人間の心理的・生理的反応特性に関する基礎的研究」, 2002 -

Awards

  • 学術賞, 2018/08
  • Charitable Trust Laboratory Medicine Research Foundation of Japan, 2015 Research grant, WATANABE, Mikio, Charitable Trust Laboratory Medicine Research Foundation of Japan, 2016/02
  • AACC Clinical Diagnostic Immunology Division Poster Award 2014, Mikio Watanabe,Naoya Inoue,Yuka Katsumata,Yoh Hidaka,yoshinori Iwatani, American Association for Clinical Chemistry, 2014/07
  • NACB Distinguished Abstract Award 2014, Mikio Watanabe,Naoya Inoue,Yuka Katsumata,Yoh Hidaka,yoshinori Iwatani, National Academy of Clinical Biochemistry, 2014/07
  • NACB Distinguished Abstract Award 2012, Mikio WATANABE, National Academy of Clinical Biochemistry, 2012/07
  • Excellent Presentation Award - The 55th Academic Meeting of the Japanese Society of Laboratory Medicine, Mikio Watanabe,Takashi Nanba,Naoya Inoue,Yoshinori Iwatani, The Japanese Society of Laboratory Medicine, 2008/11
  • The Japan Society for Clinical Immunology, Excellent Poster Award 2005, WATANABE, Mikio, The Japan Society for Clinical Immunology, 2005/10
  • 大阪大学共通教育賞, 2005/03
  • Young Investigator Award (Japan Thyroid Association), WATANABE, Mikio, Japan Thyroid Association, 2004/11
  • The Kyoto Award (Asia A)(The 18th International Congress of Clinical Chemistry and Labotratory Medicine), Mikio Watanabe, International Federation of Clinical Chemistry and Labotratory Medicine, 2002/10

Media Coverage

  • PCRの仕組み 正しく学ぶ, 2020/07/21
  • 検査の信頼性 正しく知って判断を, 2020/07/15
  • 遺伝子変化 双子で研究―疾患メカニズム解明へ―, 2017/02/17
  • 実際どうなん!?ふたご10組20人!(コメンテーター), 2016/09/19
  • 男性の遺伝子は“移り気?”, 2016/09/02
  • 働きたい 適職どこに (発達障害とともに(中)), 2008/03/07
  • 香りに癒しの効果, 2003/07/19

Academic Activities

  • 日本臨床化学会(学術誌編集委員), 2019/04 - Present
  • 日本臨床免疫学会(評議員), 2016/04 - Present
  • 日本臨床検査医学会(EBLM委員), 2014/06 - Present
  • 日本臨床化学会(評議員), 2013/09 - Present
  • Japanese Society of Laboratory Medicine (Councilor), 2008/01 - Present
  • 日本臨床化学会近畿支部(評議員), 2006/12 - Present
  • Japan Thyroid Association (Councilor), 2006/11 - Present
  • 大阪大学 学術ネットワーク(ODINS)管理運用, 1995/06 - Present
  • 大阪大学医学部附属病院外来診療, 1993/05 - Present
  • 日本臨床検査学教育学会(評議員), 2011/07 - 2013/07
  • 平成29年度 緊急臨床検査士資格認定試験, 2017/07 -
  • The 63rd National Congress of japanese Society of Laboratory Medicine, 一般社団法人 日本臨床検査医学会, 2016/09 -
  • The 55th Annual Meeting of Japanese association for Clinical Chemistry, 日本臨床化学会/Japanese association for Clinical Chemistry, 2015/10 -
  • 測定値に及ぼす環境因子解明へのアプローチ ~ふたご研究~(第68回日本臨床化学会近畿支部例会), 2015/09 -
  • The 68th Japan Society for Clinical Chemistry (JSCC) Regular Meeting of Kinki area branch, 日本臨床化学会近畿支部, 2015/09 -
  • The 57th Annual Meeting of Japan Thyroid Association, 日本甲状腺学会/Japan Thyroid Association, 2014/11 -
  • 第8回日本臨床検査学教育学会学術大会, 2013/08 -
  • 平成22年度 緊急臨床検査士資格認定試験, 2010/07 -
  • 平成21年度 緊急臨床検査士資格認定試験, 2009/07 -
  • 第50回日本臨床検査医学会近畿支部総会・第47回近畿医学検査学会合同大会, 2007/11 -
  • 第17回日本臨床化学会近畿支部総会, 2006/12 -
  • 平成18年度日本造園学会分科会, 2006/05 -
  • 第90回 二級臨床検査士資格認定試験, 2004/07 -
  • 第88回 二級臨床検査士資格認定試験, 2003/07 -
  • 第46回 日本臨床検査医学会近畿支部例会, 2002/12 -
  • 第11回 日本動物実験代替法学会, 1997/11 -

Social Activities

  • College of Laboratory Medicine of Japan (CLMJ) (Director), 2017/04 - Present
  • 公益社団法人 医学振興銀杏会(理事(会計担当業務執行理事)), 2001/06 - Present
  • Japan Society for the Promotion of Science, 2014/10 - 2016/09

Committee Memberships

  • College of Laboratory Medicine of Japan, Director, 2017/03 - Present
  • 評議員, 2016/01 - Present
  • 評議員, 2013 - Present
  • Japanese Society of Laboratory Medicine, Councillor, 2007/01 - Present
  • Japan Thyroid Association, Councillor, 2006/10 - Present
  • Director, 2001/06 - Present
  • 評議員, 2011/04 - 2013/03
  • 認定健康食品管理士, -
  • 認定サイトメトリー技術者, -
  • 認定臨床化学者, -
  • 認定甲状腺専門医, -