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Takahashi Yusuke
高橋　雄介
Takahashi Yusuke
高橋　雄介
Institutional repository
Osaka University Dental Hospital, Associate Professor (Lecturer)

keyword Vital Pulp Treatment，Irreversible pulpitis，reversible pulpitis，pulp biology odontoblast reparative dentin

Institutional repository

Research History 7

  1. 2015/04/01 - Present
    Osaka University Osaka University Dental Hospital　Restorative Dentistry and Endodontology　Associate Professor

  2. 2010/05 - 2015/03
    Osaka University Graduate School of Dentistry Department of Restorative Dentistry and Endodontology, Assistant Professor

  3. 2009/05 - 2010/04
    The University of Birmingham School of Dentistry, Department of Oral Biology, Honorary Visiting Research Fellow

  4. 2007/04 - 2009/03
    Assistant Professor

  5. 2006/01/01 - 2007/03/31
    Osaka University Graduate School of Dentistry Course for Molecular Oral Biology and Dentistry　Research Assistant

  6. 2005/04/01 - 2005/12/31
    Osaka University Graduate School of Dentistry Course for Molecular Oral Biology and Dentistry　Specially Appointed Researcher

  7. 2002/04 - 2005/03
    大阪大学歯学部附属病院・医員

Education 2

  1. Osaka University　Graduate School, Division of Dental Research

    - 2002/03

  2. Osaka University　Faculty of Dentistry

    - 1998/03

Professional Memberships 8

  1. Japanese Society for Laser Dentistry

  2. 日本歯内療法学会

  3. Japanese Association for Dental Research

  4. International Association for Dental Research

  5. Japanese Association for Dental Research

  6. International Association for Dental Research

  7. 日本歯科保存学会

  8. 大阪大学歯学会

Research Areas 1

  1. Life sciences / Conservative dentistry and endodontics /

Awards 7

  1. Dean Award of Osaka University Graduate School of Dentistry

    Yusuke Takahashi　Osaka University Graduate School of Dentisry　2020/10

  2. Osaka University Dental Society Excellent Research Encouragement Award

    Manahil Ali, Motoki Okamoto, Shungo Komichi, Masakatsu Watanabe, Hailing Huang, Yusuke Takahashi, Mikako Hayashi　The Osaka University Dental Society　2020/06

  3. 平成30年度大阪大学歯学研究科長賞（研究分野）

    高橋雄介　大阪大学大学院歯学研究科　2019/03

  4. 日本レー ザー歯学会優秀発表賞

    岡本基岐　日本レーザー歯学会　2017/09

  5. 大阪大学総長奨励賞

    高橋雄介　大阪大学　2014/07

  6. 日本歯科保存学会 年間優秀論文賞

    高橋雄介　日本歯科保存学会　2014/06

  7. 日本歯科保存学会奨励賞

    高橋 雄介　日本歯科保存学会　2005/06

Papers 56

  1. Effect of Heparan Sulfate on Vasculogenesis and Dentinogenesis of Dental Pulp Stem Cells

    Aonan Li, Jun-Ichi Sasaki, Hailing Huang, Gabriela L. Abe, Toshihiro Inubushi, Yusuke Takahashi, Mikako Hayashi, Satoshi Imazato

    Journal of Endodontics　Vol. 50　No. 8　p. 1108-1116　2024/08　Research paper (scientific journal)

    Publisher: Elsevier BV

  2. Effects of Sodium Hypochlorite Concentration and Application Time on Bacteria in an Ex Vivo Polymicrobial Biofilm Model.

    Hazuki Maezono, Kittipit Klanliang, Tsuyoshi Shimaoka, Yoko Asahi, Yusuke Takahashi, Zhejun Wang, Ya Shen, Markus Haapasalo, Mikako Hayashi

    Journal of endodontics　Vol. 50　No. 6　p. 814-819　2024/06　Research paper (scientific journal)

  3. Editorial: Molecular pathways and novel therapeutic targets in regenerative dentistry

    Bruno Cavalcanti, Waruna Lakmal Dissanayaka, Yusuke Takahashi

    Frontiers in Dental Medicine　Vol. 5　2024/05/20　Research paper (scientific journal)

    Publisher: Frontiers Media SA

  4. Mechanical behavior of endodontically treated teeth: A three‐dimensional finite element analysis using displacement vector

    Ryousuke Tanaka, Satoshi Yamaguchi, Yusuke Takahashi, Satoshi Imazato, Mikako Hayashi

    Journal of Prosthodontics　2024/01/12　Research paper (scientific journal)

  5. On-demand chlorine dioxide solution enhances odontoblast differentiation through desulfation of cell surface heparan sulfate proteoglycan and subsequent activation of canonical Wnt signaling

    Toshihiro Inubushi, Nag Priyanka, Masakatsu Watanabe, Yusuke Takahashi, Shinnosuke Kusano, Hiroshi Kurosaka, Silvana Papagerakis, Petros Papagerakis, Mikako Hayashi, Takashi Yamashiro

    Frontiers in Cell and Developmental Biology　Vol. 11　p. 1271455-1271455　2023/10/26　Research paper (scientific journal)

    Publisher: Frontiers Media SA

  6. ラットう蝕由来可逆性歯髄炎モデルを用いたレジン成分含有ケイ酸カルシウムセメントの評価

    松本 紗也子, 岡本 基岐, 黄 海玲, 森山 輝一, 中谷 公貴, 渡邉 昌克, 高橋 雄介, 林 美加子

    特定非営利活動法人日本歯科保存学会学術大会プログラムおよび講演抄録集　Vol. 159回　p. 112-112　2023/10

    Publisher: (NPO)日本歯科保存学会

  7. Analyzing the anti-caries effect of fluoride varnish containing tricalcium phosphate using PIXE/PIGE

    Reo UEMURA, Hiroko YAMAMOTO, Katsuaki NAITO, Hikaru KANDA, Yusuke TAKAHASHI, Mikako HAYASHI

    Dental Materials Journal　Vol. 42　No. 4　p. 591-597　2023/07/25　Research paper (scientific journal)

    Publisher: Japanese Society for Dental Materials and Devices

  8. Repair of an Extensive External Cervical Resorption Lesion Using Intentional Replantation with Crown Rotation

    Motoki Okamoto, Yoko Asahi, Henry Fergus Duncan, Nanako Kuriki, Yusuke Takahashi, Mikako Hayashi

    Case Reports in Dentistry　Vol. 2023　p. 1-10　2023/06/26　Research paper (scientific journal)

    Publisher: Hindawi Limited

  9. Case report: Delayed autologous tooth transplantation based on objective bone healing of the extraction socket (4-year follow-up)

    Yusuke Takahashi, Shotaro Abe, Motoki Okamoto, Tomomi Tsujimoto, Shumei Murakami, Mikako Hayashi

    Frontiers in Dental Medicine　Vol. 4　2023/06/15　Research paper (scientific journal)

    Publisher: Frontiers Media SA

  10. 骨形成不全症患者の慢性根尖性歯周炎罹患歯に対応した1症例

    前薗葉月, 川西雄三, 島岡毅, 高橋雄介, 林美加子

    日本歯科保存学雑誌　Vol. 66　No. 2　p. 131-137　2023/06　Research paper (scientific journal)

  11. NaOC1およびEDTAが根管象牙質に与える影響の形態学的評価 根管系実験モデルを用いた検討

    川西 雄三, 前薗 葉月, 島岡 毅, 北谷 匠, 内藤 克昭, 高橋 雄介, 林 美加子

    特定非営利活動法人日本歯科保存学会学術大会プログラムおよび講演抄録集　Vol. 158回　p. 111-111　2023/05

    Publisher: (NPO)日本歯科保存学会

  12. Development of Rat Caries-Induced Pulpitis Model for Vital Pulp Therapy

    H. Huang, M. Okamoto, M. Watanabe, S. Matsumoto, K. Moriyama, S. Komichi, M. Ali, S. Matayoshi, R. Nomura, K. Nakano, Y. Takahashi, M. Hayashi

    Journal of Dental Research　Vol. 102　No. 5　p. 574-582　2023/05　Research paper (scientific journal)

  13. Morphological Analyses of Effects of Endodontic Irrigant Solutions Using a Root Canal Model and an Immersion Model.

    Yuzo Kawanishi, Hazuki Maezono, Tsuyoshi Shimaoka, Takumi Kitatani, Katsuaki Naito, Maki Sotozono, Kittipit Klanliang, Yusuke Takahashi, Mikako Hayashi

    International journal of dentistry　Vol. 2023　p. 3938522-3938522　2023　Research paper (scientific journal)

  14. Novel Functional Peptide for Next-Generation Vital Pulp Therapy

    M. Watanabe, M. Okamoto, S. Komichi, H. Huang, S. Matsumoto, K. Moriyama, J. Ohshima, S. Abe, M. Morita, M. Ali, K. Takebe, I. Kozaki, A. Fujimoto, K. Kanie, R. Kato, K. Uto, M. Ebara, A. Yamawaki-Ogata, Y. Narita, Y. Takahashi, M. Hayashi

    Journal of Dental Research　p. 002203452211357-002203452211357　2022/11/22　Research paper (scientific journal)

    Publisher: SAGE Publications

  15. 要時生成型亜塩素酸イオン水溶液がEnterococcus faecalisバイオフィルムに及ぼす影響

    島岡 毅, 前薗 葉月, 川西 雄三, 朝日 陽子, 高橋 雄介, 林 美加子

    特定非営利活動法人日本歯科保存学会学術大会プログラムおよび講演抄録集　Vol. 157回　p. 33-33　2022/10

    Publisher: (NPO)日本歯科保存学会

  16. Biological Evaluation of the Effect of Root Canal Sealers Using a Rat Model

    Motoki Okamoto, Sayako Matsumoto, Kiichi Moriyama, Hailing Huang, Masakatsu Watanabe, Jiro Miura, Keita Sugiyama, Yujiro Hirose, Manabu Mizuhira, Nanako Kuriki, Julian G. Leprince, Yusuke Takahashi, Shigetada Kawabata, Mikako Hayashi

    Pharmaceutics　Vol. 14　No. 10　p. 2038-2038　2022/09/24　Research paper (scientific journal)

    Publisher: MDPI AG

  17. 次世代の歯髄保存療法を目指したペプチド覆髄材

    高橋雄介

    日本歯科保存学雑誌　Vol. 65　No. 2　p. 115-119　2022/06　Research paper (scientific journal)

  18. Biological properties of lithium-containing surface pre-reacted glass fillers as direct pulp-capping cements

    Manahil Ali, Motoki Okamoto, Masakatsu Watanabe, Hailing Huang, Sayako Matsumoto, Shungo Komichi, Yusuke Takahashi, Mikako Hayashi

    Dental Materials　Vol. 38　No. 2　p. 294-308　2022/02　Research paper (scientific journal)

    Publisher: Elsevier BV

  19. Partial Pulpotomy to Successfully Treat a Caries-Induced Pulpal Micro-Abscess: A Case Report

    Okamoto Motoki, Duncan Henry Fergus, Takahashi Yusuke, Kuriki Nanako, Sayako Matsumoto, Hayashi Mikako

    Frontiers in Dental Medicine　Vol. 2　2021/06/22　Research paper (scientific journal)

    Publisher: Frontiers Media SA

  20. A Case Report: Endodontic-periodontal Disease Due to Root Malformation

    Motoki OKAMOTO, Yoshifumi KINOMOTO, Nanako KURIKI, Keigo SAWADA, Yusuke TAKAHASHI, Shinya MURAKAMI, Mikako HAYASHI

    The Japanese Journal of Conservative Dentistry　Vol. 64　No. 2　p. 171-180　2021

    Publisher: The Japanese Society of Conservative Dentistry

  21. Evaluation of physical properties of fiber-reinforced composite resin

    Naoko Suzaki, Satoshi Yamaguchi, Nanako Hirose, Ryousuke Tanaka, Yusuke Takahashi, Satoshi Imazato, Mikako Hayashi

    Dental Materials　Vol. 36　No. 8　p. 987-996　2020/08　Research paper (scientific journal)

  22. Cytotoxicity of S-PRG fillers: Direct exposure of fillers and eluates from the fillers to RAW264 cells

    Hashimoto, M., Kitagawa, H., Takahashi, Y., Hayashi, M., Imazato, S.

    Nano Biomedicine　Vol. 12　No. 1　p. 3-10　2020/06　Research paper (scientific journal)

  23. Performance of a Biodegradable Composite with Hydroxyapatite as a Scaffold in Pulp Tissue Repair

    Motoki Okamoto, Sayako Matsumoto, Ayato Sugiyama, Kei Kanie, Masakatsu Watanabe, Hailing Huang, Manahil Ali, Yuki Ito, Jiro Miura, Yujiro Hirose, Koichiro Uto, Mitsuhiro Ebara, Ryuji Kato, Aika Yamawaki-Ogata, Yuji Narita, Shigetada Kawabata, Yusuke Takahashi, Mikako Hayashi

    Polymers　Vol. 12　No. 4　p. 937-937　2020/04/17　Research paper (scientific journal)

    Publisher: MDPI AG

  24. Author Correction: Dentinogenic effects of extracted dentin matrix components digested with matrix metalloproteinases (Scientific Reports, (2018), 8, 1, (10690), 10.1038/s41598-018-29112-3)

    Okamoto, M., Takahashi, Y., Komichi, S., Cooper, P.R., Hayashi, M.

    Scientific Reports　Vol. 10　No. 1　2020　Research paper (scientific journal)

  25. Bonding performance of a newly developed one-step single-bottle adhesive on sound human dentin with different tubule orientations

    Koytchev, E., Takahashi, Y., Suzaki, N., Okamoto, M., Hayashi, M.

    Series on Biomechanics　Vol. 34　No. 1　p. 3-11　2020/01　Research paper (scientific journal)

  26. Investigation on Effective Education Methods for Preparing Curved-root Canal with FKG Race Part 2. Proficiency of J- and S-shaped Root Canal Preparation by Using Nickel-titanium File FKG Race

    OHSHIMA Jun, KAWANISHI Yuzo, OKA Shintaro, YAMADA Tomomi, YAMAGUCHI Mikiyo, ASAHI Yoko, SOTOZONO Maki, KAGIOKA Takumi, WATANABE Masakatsu, NAITO Katsuaki, ABE Shoutaro, UEMURA Reo, TAKAHASHI Yusuke, ITOH Shousaku, HAYASHI Mikako

    Japanese Journal of Conservative Dentistry　Vol. 62　No. 6　p. 263-270　2019/12　Research paper (scientific journal)

    Publisher:

  27. Surface Pre-Reacted Glass Filler Contributes to Tertiary Dentin Formation through a Mechanism Different Than That of Hydraulic Calcium-Silicate Cement.

    Motoki Okamoto, Manahil Ali, Shungo Komichi, Masakatsu Watanabe, Hailing Huang, Yuki Ito, Jiro Miura, Yujiro Hirose, Manabu Mizuhira, Yusuke Takahashi, Daisuke Okuzaki, Shigetada Kawabata, Satoshi Imazato, Mikako Hayashi

    Journal of clinical medicine　Vol. 8　No. 9　p. 1440-1440　2019/09/11　Research paper (scientific journal)

  28. Lithium-containing surface pre-reacted glass fillers enhance hDPSC functions and induce reparative dentin formation in a rat pulp capping model through activation of Wnt/β-catenin signaling.

    Manahil Ali, Motoki Okamoto, Shungo Komichi, Masakatsu Watanabe, Hailing Huang, Yusuke Takahashi, Mikako Hayashi

    Acta Biomaterialia　Vol. 96　p. 594-604　2019/09　Research paper (scientific journal)

  29. Protein S100-A7 Derived from Digested Dentin Is a Critical Molecule for Dentin Pulp Regeneration.

    Shungo Komichi, Yusuke Takahashi, Motoki Okamoto, Manahil Ali, Masakatsu Watanabe, Hailing Huang, Takeo Nakai, Paul Cooper, Mikako Hayashi

    Cells　Vol. 8　No. 9　2019/08　Research paper (scientific journal)

  30. Effect of tissue inhibitor of metalloprotease 1 on human pulp cells in vitro and rat pulp tissue in vivo.

    M Okamoto, Y Takahashi, S Komichi, M Ali, M Watanabe, M Hayashi

    International endodontic journal　Vol. 52　No. 7　p. 1051-1062　2019/07　Research paper (scientific journal)

  31. Application of a direct pulp capping cement containing S-PRG filler

    Takahashi, Y., Okamoto, M., Komichi, S., Imazato, S., Nakatsuka, T., Sakamoto, S., Kimoto, K., Hayashi, M.

    Clinical Oral Investigations　Vol. 23　No. 4　p. 1723-1731　2019/04/29　Research paper (scientific journal)

    Publisher: Springer Science and Business Media {LLC}

  32. Dentinogenic effects of extracted dentin matrix components digested with matrix metalloproteinases

    Okamoto, M., Takahashi, Y., Komichi, S., Cooper, P.R., Hayashi, M.

    Scientific Reports　Vol. 8　No. 1　2018/07　Research paper (scientific journal)

  33. Novel evaluation method of dentin repair by direct pulp capping using high-resolution micro-computed tomography

    Motoki Okamoto, Yusuke Takahashi, Shungo Komichi, Manahil Ali, Naomichi Yoneda, Takuya Ishimoto, Takayoshi Nakano, Mikako Hayashi

    Clinical Oral Investigations　Vol. 22　p. 1-9　2018/02/12　Research paper (scientific journal)

    Publisher: Springer Verlag

  34. Efficacy of Er:YAG Laser in Vital Pulp Therapy

    Motoki OKAMOTO, Shungo KOMICHI, Masakatu WATANABE, Kyoko YAGI, Haruna NARUSE, Yuki ITO, Yusuke TAKAHASHI, Mikako HAYASHI

    Journal of Japanese Society for Laser Dentistry　Vol. 29　No. 1　p. 1-9　2018　Research paper (scientific journal)

    Publisher: Japanese Society for Laser Dentistry

  35. Mechanism of detoxification of the cationic antibacterial monomer 12-methacryloyloxydodecylpyridiniumbromide (MDPB) by N-acetyl cysteine

    Ma, S., Imazato, S., Takahashi, Y., Kiba, W., Takeda, K., Izutani, N., Kitagawa, H., Chen, J.

    Dental Materials　Vol. 29　No. 12　p. 1219-1227　2013/06　Research paper (scientific journal)

  36. Mechanism of detoxification of the cationic antibacterial monomer 12-methacryloyloxydodecylpyridiniumbromide (MDPB) by N-acetyl cysteine.

    Ma S, Imazato S, Takahashi Y, Kiba W, Takeda K, Izutani N, Kitagawa H, Chen J

    Dental Materials Journal　Vol. 29　p. 1219-1227　2013/06　Research paper (scientific journal)

  37. Activation of the Wnt/β-catenin pathway and tissue inhibitor of metalloprotease 1 during tertiary dentinogenesis

    Seisuke Yoshioka, Yusuke Takahashi, Makoto Abe, Ikumi Michikami, Satoshi Imazato, Satoshi Wakisaka, Mikako Hayashi, Shigeyuki Ebisu

    Journal of Biochemistry　Vol. 153　No. 1　p. 43-50　2013/01　Research paper (scientific journal)

  38. Effect of Er: YAG Laser Irradiation on Residual Bacteria in the Cavity

    Yusuke Takahashi, Seisuke Yoshioka, Yoko Asahi, Tomotaka Nagayama, Yuichiro Noiri, Mikako Hayashi

    The Japanese Journal of Conservative Dentistry　Vol. 56　No. 1　p. 1-8　2013/01　Research paper (scientific journal)

    Publisher: The Japanese Society of Conservative Dentistry

  39. Dentine as a bioactive extracellular matrix

    A. J. Smith, B. A. Scheuen, Y. Takahashi, J. L. Ferracane, R. M. Shelton, P. R. Cooper

    ARCHIVES OF ORAL BIOLOGY　Vol. 57　No. 2　p. 109-121　2012/02

  40. Effects of the antibacterial monomer 12-methacryloyloxydodecylpyridinium bromide (MDPB) on bacterial viability and metabolism

    Naomi Izutani, Satoshi Imazato, Kazuko Nakajo, Nobuhiro Takahashi, Yusuke Takahashi, Shigeyuki Ebisu, Roy R.B. Russell

    European Journal of Oral Sciences　Vol. 119　No. 2　p. 175-181　2011/04　Research paper (scientific journal)

  41. Efficacy of polyphasic calcium phosphates as a direct pulp capping material

    Kiba, W., Imazato, S., Takahashi, Y., Yoshioka, S., Ebisu, S., Nakano, T.

    Journal of Dentistry　Vol. 38　No. 10　2010/10　Research paper (scientific journal)

    Publisher: Elsevier

  42. Inflammation-regeneration interplay in the dentine-pulp complex

    Paul R. Cooper, Yusuke Takahashi, Lee W. Graham, Stephane Simon, Satoshi Imazato, Anthony J. Smith

    JOURNAL OF DENTISTRY　Vol. 38　No. 9　p. 687-697　2010/09　Research paper (scientific journal)

  43. The influence of the antibacterial monomer 12-methacryloyloxydodecylpyridinium bromide on the proliferation, differentiation and mineralization of odontoblast-like cells

    Mariko Nishida, Satoshi Imazato, Yusuke Takahashi, Shigeyuki Ebisu, Takuya Ishimoto, Takayoshi Nakano, Yoshiyuki Yasuda, Takashi Saito

    BIOMATERIALS　Vol. 31　No. 7　p. 1518-1532　2010/03　Research paper (scientific journal)

  44. Fluoride released from glass-ionomer cement is responsible to inhibit the acid production of caries-related oral streptococci

    Kazuko Nakajo, Satoshi Imazato, Yusuke Takahashi, Wakako Kiba, Shigeyuki Ebisu, Nobuhiro Takahashi

    DENTAL MATERIALS　Vol. 25　No. 6　p. 703-708　2009/06　Research paper (scientific journal)

  45. An in vivo evaluation of bonding ability of comprehensive antibacterial adhesive system incorporating MDPB

    Satoshi Imazato, Franklin R. Tay, Andrea V. Kaneshiro, Yusuke Takahashi, Shigeyuki Ebisu

    DENTAL MATERIALS　Vol. 23　No. 2　p. 170-176　2007/02　Research paper (scientific journal)

  46. Antibacterial effect of chlorhexidine-containing glass ionomer cement in vivo: A pilot study

    J. E. Frencken, S. Imazato, C. Toi, J. Mulder, S. Mickenautsch, Y. Takahashi, S. Ebisu

    CARIES RESEARCH　Vol. 41　No. 2　p. 102-107　2007　Research paper (scientific journal)

  47. Pulpal Reactions and in vivo Bonding Interface of Antibacterial Self-etching System Incorporating MDPB

    S. Imazato, Y. Noiri, Y. Takahashi, N. Noguchi, M. Hayashi, S. Ebisu

    The Japanese Journal of Conservative Dentistry　Vol. 49　No. 4　p. 523-529　2006/08　Research paper (scientific journal)

    Publisher: The Japanese Society of Conservative Dentistry

  48. Antibacterial effects and physical properties of glass-ionomer cements containing chlorhexidine for the ART approach

    Yusuke Takahashi, Satoshi Imazato, Andrea V. Kaneshiro, Shigeyuki Ebisu, Jo E. Frencken, Franklin R. Tay

    DENTAL MATERIALS　Vol. 22　No. 7　p. 647-652　2006/07　Research paper (scientific journal)

  49. In vitro antibacterial effects of the dentin primer of Clearfil Protect Bond

    S Imazato, A Kuramoto, Y Takahashi, S Ebisu, MC Peters

    DENTAL MATERIALS　Vol. 22　No. 6　p. 527-532　2006/06　Research paper (scientific journal)

  50. Fracture resistance of pulpless teeth restored with post-cores and crowns

    M Hayashi, Y Takahashi, S Imazato, S Ebisu

    DENTAL MATERIALS　Vol. 22　No. 5　p. 477-485　2006/05　Research paper (scientific journal)

  51. Clinical Evaluation of the Objectivity of Caries Removal Using a Caries Detector Dye

    Iwami Y, Shimizu A, Yamamoto H, kawakami Y, Itoh S, Takahashi Y, Yabune T, Ebisu S

    Japanese Jounal of Conservative Dentistry　2004/10　Research paper (scientific journal)

  52. In vivo antibacterial effects of dentin primer incorporating MDPB

    IMAZATO S.

    Oper. Dent.　Vol. 29　p. 369-375　2004/08　Research paper (scientific journal)

  53. 齲蝕検知液を用いたう蝕除去の客観性についての臨床評価

    岩見行晃, 清水亜矢子, 山本洋子, 川上克子, 伊藤祥作, 高橋雄介, 薮根敏晃, 金子智之, 恵比須繁之

    日歯保存誌　Vol. 47　No. 5　p. 716-722　2004　Research paper (scientific journal)

  54. Effects of chlorhexidine, minocycline, and metronidazole on Porphyromonas gingivalis strain 381 in biofilms

    Yuichiro Noiri, Yumiko Okami, Masahiro Narimatsu, Yusuke Takahashi, Takashi Kawahara, Shigeyuki Ebisu

    Journal of Periodontology　Vol. 74　No. 11　p. 1647-1651　2003/11　Research paper (scientific journal)

  55. Antibacterial activity of bactericide-immobilized filler for resin-based restoratives

    S Imazato, N Ebi, Y Takahashi, T Kaneko, S Ebisu, RRB Russell

    BIOMATERIALS　Vol. 24　No. 20　p. 3605-3609　2003/09　Research paper (scientific journal)

  56. FROM Seltzer and Bender’s DENTAL PULP－う蝕による歯髄への感染－

    高橋雄介, 恵比須繁之

    ザ・クインテッセンス　2003/08

Misc. 58

  1. Morphological analyses of effects of NaOCl and EDTA on dentin using a root canal model

    川西雄三, 前薗葉月, 島岡毅, 北谷匠, 内藤克昭, 高橋雄介, 林美加子

    日本歯科保存学会学術大会プログラムおよび講演抄録集(Web)　Vol. 158th　2023

  2. A Case Report: Successful Root Canal Treatment Using Resin Sealer Without Gutta-percha Point.

    森山輝一, 岡本基岐, 松本紗也子, 渡邉昌克, 中谷公貴, 岩崎幸司, 齋多遼太郎, 西村有起, 高橋雄介, 林美加子

    日本歯科保存学会学術大会プログラムおよび講演抄録集(Web)　Vol. 158th　2023

  3. Evaluation of Calcium Silicate Cements Containing Resin Components Using a Rat Caries-Derived Reversible Pulpitis Model

    松本紗也子, 岡本基岐, HUANG Hailing, 森山輝一, 中谷公貴, 渡邉昌克, 高橋雄介, 林美加子

    日本歯科保存学会学術大会プログラムおよび講演抄録集(Web)　Vol. 159th　2023

  4. Evaluation of the localization of leptin in a rat caries derived pulpitis model

    森山輝一, 岡本基岐, 松本紗也子, 渡邉昌克, HUANG Hailing, 高橋雄介, 林美加子

    日本歯科保存学会学術大会プログラムおよび講演抄録集(Web)　Vol. 156th　2022

  5. Establishment of novel diagnostic methods for reversible and irreversible pulpitis associated with caries progression using ultra-high magnetic field MRI

    森山輝一, 岡本基岐, 松本紗也子, 渡邉昌克, HUANG Hailing, 中谷公貴, 高橋雄介, 林美加子

    日本歯科保存学会学術大会プログラムおよび講演抄録集(Web)　Vol. 157th　2022

  6. Search for the functional site of a protein that promotes pulpal wound healing process

    渡邉昌克, 岡本基岐, 小道俊吾, HAILING Huang, 松本紗也子, 森山輝一, 高橋雄介, 林美加子

    日本歯科保存学会学術大会プログラムおよび講演抄録集(Web)　Vol. 156th　2022

  7. 応用したい!さまざまな材料からみた臨床テクニック 洗浄編-3 根管洗浄によるスミヤー層除去および象牙質脱灰の形態学的検討

    川西雄三, 前薗葉月, 高橋雄介, 林美加子

    Quintessence　2021

  8. 根管充填用シーラーが生体組織に与える影響のラット皮下埋入モデルを用いた評価

    松本紗也子, 岡本基岐, 森山輝一, 渡邉昌克, 黄海玲, 三浦治郎, 杉山敬多, 高橋雄介, 林美加子

    日本再生医療学会総会(Web)　Vol. 20th　2021

  9. Effect of calcium hydroxide intracanal medicament on wound healing of periapical tissue

    森山輝一, 岡本基岐, 松本紗也子, 渡邉昌克, HUANG Hailing, 高橋雄介, 林美加子

    日本歯科保存学会学術大会プログラムおよび講演抄録集(Web)　Vol. 154th　2021

  10. Evaluation of root canal preparation ability using a novel drive system

    岡本基岐, 松本紗也子, 森山輝一, 渡邉昌克, HUANG Hailing, 三浦治郎, 杉山敬多, 米田直道, 的場一成, 高橋雄介, 林美加子

    日本歯科保存学会学術大会プログラムおよび講演抄録集(Web)　Vol. 154th　2021

  11. 根尖周囲組織の創傷治癒過程においてBMP由来ペプチドが与える影響についての相互作用解析

    渡邉昌克, 岡本基岐, 松本沙也子, 森山輝一, 高橋雄介, 林美加子

    日本歯科医師会雑誌　Vol. 74　No. 4　2021

  12. 新規駆動形式NiTiロータリーファイルの根管形成能の評価

    岡本基岐, 松本紗也子, 森山輝一, 渡邉昌克, 的場一成, 高橋雄介, 林美加子

    日本歯科医師会雑誌　Vol. 74　No. 4　2021

  13. Morphological investigation of dentin erosion after root canal irrigation

    川西雄三, 植木柚衣, 西村佳保里, 内藤克昭, 外園真規, 前薗葉月, 高橋雄介, 林美加子

    日本歯内療法学会学術大会プログラム・抄録集　Vol. 41st　2020

  14. Effect of Super MTA Paste on the wound healing process of pulp tissue

    松本紗也子, 岡本基岐, 渡邉昌克, ALI Manahil, HUANG Hailing, 小道俊吾, 高橋雄介, 林美加子

    日本歯科保存学会学術大会プログラムおよび講演抄録集(Web)　Vol. 152nd　2020

  15. 生物学的覆髄材料の臨床的評価を目指したラット覆髄モデルの開発

    岡本基岐, 高橋雄介, HUANG Hailing, 小道俊吾, ALI Manahil, 渡邉昌克, 松本紗也子, 林美加子

    日本歯科保存学会学術大会プログラムおよび講演抄録集(Web)　Vol. 151st　2019

  16. 生物学的根拠に基づくペプチド覆髄剤の開発

    高橋雄介, 渡邉昌克, 岡本基岐, 小道俊吾, ALI Manahil, HUANG Hailing, 松本紗也子, 林美加子

    日本歯科保存学会学術大会プログラムおよび講演抄録集(Web)　Vol. 151st　2019

  17. S-PRGセメントによる第三象牙質形成機序の解明

    岡本基岐, MANAHIL ALi, 小道俊吾, 渡邉昌克, 黄海玲, 伊藤勇紀, 三浦治郎, 広瀬雄二郎, 水平学, 高橋雄介, 川端重忠, 今里聡, 林美加子

    日本再生医療学会総会(Web)　Vol. 18th　2019

  18. 歯髄創傷治癒過程におけるProtein S100-A7の局在解析

    小道俊吾, 高橋雄介, 岡本基岐, ALI Manahil. S, 渡邉昌克, 林美加子

    日本歯科保存学会学術大会プログラムおよび講演抄録集(Web)　Vol. 148th　2018

  19. Er:YAGレーザーの歯髄保存療法における有効性の検討

    岡本基岐, 小道俊吾, 渡邉昌克, 八木香子, 成瀬陽菜, 伊藤勇紀, 高橋雄介, 林美加子

    日本レーザー歯学会総会・学術大会プログラム・講演抄録集　Vol. 29th　2017

  20. S-PRGフィラー含有セメントのEndodonticセメントとしての応用

    岡本基岐, 小道俊吾, 伊藤勇紀, 栗木菜々子, 渡邉昌克, 高橋雄介, 林美加子

    日本歯内療法学会学術大会プログラム・抄録集　Vol. 38th　2017

  21. 低酸素誘導因子(HIF-1)による第三象牙質形成に与える影響

    岡本基岐, 小道俊吾, MANAHIL Ali, 渡邉昌克, 高橋雄介, 林美加子

    日本歯科保存学会学術大会プログラムおよび講演抄録集(Web)　Vol. 147th　2017

  22. Effects of the antibacterial monomer 12-methacryloyloxydodecylpyridinium bromide (MDPB) on bacterial viability and metabolism

    Naomi Izutani, Satoshi Imazato, Kazuko Nakajo, Nobuhiro Takahashi, Yusuke Takahashi, Shigeyuki Ebisu, Roy R. B. Russell

    EUROPEAN JOURNAL OF ORAL SCIENCES　Vol. 119　No. 2　p. 175-181　2011/04

  23. Effects of the antibacterial monomer 12-methacryloyloxydodecylpyridinium bromide (MDPB) on bacterial viability and metabolism

    N. Izutani, S. Imazato, K. Nakajo, N. Takahashi, Y. Takahashi, S. Ebisu, R.R. Russell

    Eur. J. Oral. Sci.　Vol. 119 (2): 175-181　2011/04

  24. Efficacy of polyphasic calcium phosphates as a direct pulp capping material

    Wakako Kiba, Satoshi Imazato, Yusuke Takahashi, Seisuke Yoshioka, Sigeyuki Ebisu, Takayoshi Nakano

    JOURNAL OF DENTISTRY　Vol. 38　No. 10　p. 828-837　2010/10

  25. Efficacy of polyphasic calcium phosphates as a direct pulp capping material

    Wakako Kiba, Satoshi Imazato, Yusuke Takahashi, Seisuke Yoshioka, Sigeyuki Ebisu, Takayoshi Nakano

    JOURNAL OF DENTISTRY　Vol. 38　No. 10　p. 828-837　2010/10

  26. Inflammation-regeneration interplay in the dentine-pulp complex

    Paul R. Cooper, Yusuke Takahashi, Lee W. Graham, Stephane Simon, Satoshi Imazato, Anthony J. Smith

    JOURNAL OF DENTISTRY　Vol. 38　No. 9　p. 687-697　2010/09　Book review, literature introduction, etc.

  27. Inflammation-regeneration interplay in the dentine-pulp complex

    Cooper PR, Takahashi Y, Graham LW, Simon S, Imazato S, Smith AJ

    Journal of Dentistry　Vol. 38　No. 9　p. 687-697　2010/09　Book review, literature introduction, etc.

  28. The influence of the antibacterial monomer 12-methacryloyloxydodecylpyridinium bromide on the proliferation, differentiation and mineralization of odontoblast-like cells

    Mariko Nishida, Satoshi Imazato, Yusuke Takahashi, Shigeyuki Ebisu, Takuya Ishimoto, Takayoshi Nakano, Yoshiyuki Yasuda, Takashi Saito

    BIOMATERIALS　Vol. 31　No. 7　p. 1518-1532　2010/03

  29. The influence of the antibacterial monomer 12-Methacryloyloxydodecylpyridinium bromide on the proliferation, differentiation and mineralization of odontoblast-like cells.

    Nishida M, Imazato S, Takahashi Y, Ebisu S, Ishimoto T, Nakano T, Yasuda Y, Saito T

    Biomaterials　Vol. 31　No. 7　p. 1518-1532　2010/03

  30. Dental tissue inflammation and regeneration

    Nova Science Publishers　2010

  31. Dental tissue inflammation and regeneration

    Nova Science Publishers　2010

  32. Fluoride released from glass-ionomer cement is responsible to inhibit the acid production of caries-related oral streptococci

    Kazuko Nakajo, Satoshi Imazato, Yusuke Takahashi, Wakako Kiba, Shigeyuki Ebisu, Nobuhiro Takahashi

    Dental Materials　Vol. 25　No. 6　p. 703-708　2009/06

    Publisher: Elsevier

  33. Fluoride released from glass-ionomer cement is responsible to inhibit the acid production of caries-related oral streptococci

    Kazuko Nakajo, Satoshi Imazato, Yusuke Takahashi, Wakako Kiba, Shigeyuki Ebisu, Nobuhiro Takahashi

    DENTAL MATERIALS　Vol. 25　No. 6　p. 703-708　2009/06

  34. 保存修復学専門用語集

    医歯薬出版　2009

  35. Static And Fatigue Fracture Resistances Of Pulpless Teeth Restored With Post-Cores

    Dent. Mater.　Vol. 24 (9): 1178-1186　2008

  36. Effects of antibacterial monomer MDPB on proliferation, differentiation and mineralization of odontoblast-like cells

    NISHIDA Mariko, IMAZATO Satoshi, TAKAHASHI Yusuke, YASUDA Yoshiyuki, SAITO Takashi, EBISU Shigeyuki

    Vol. 50　p. 8-8　2007/10/05

  37. Application of Poly-phasic Calcium Phosphates to Direct Pulp Capping : Evaluation of Induction of Reparative Dentin in Rat Pulp

    KIBA Wakako, IMAZATO Satoshi, TAKAHASHI Yusuke, YOSHIOKA Seisuke, EBISU Shigeyuki, NAKANO Takayoshi, UMAKOSHI Yukichi

    Vol. 50　p. 9-9　2007/10/05

  38. Antibacterial effect of chlorhexidine-containing glass ionomer cement in vivo: a pilot study

    J. E. Frencken, S. Imazato, C. Toi, J. Mulder, S. Mickenautsch, Y. Takahashi, S. Ebisu

    Caries Research　Vol. 41　No. 2　p. 102-107　2007/02

  39. An in vivo evaluation of bonding ability of comprehensive antibacterial adhesive system incorporating MDPB

    Satoshi Imazato, Franklin R. Tay, Andrea V. Kaneshiro, Yusuke Takahashi, Shigeyuki Ebisu

    DENTAL MATERIALS　Vol. 23　No. 2　p. 170-176　2007/02

  40. Eluate from fluoride-releasing restorative materials inhibits acid production of caries-related bacteria

    NAKAJO Kazuko, TAKAHASHI Yusuke, KIBA Wakako, IMAZATO Satoshi, TAKAHASHI Nobuhiro

    Vol. 49　p. 62-62　2006/10/11

  41. Analysis of resin polymerization on the surface of oral streptococci

    TAKAHASHI Yusuke, IMAZATO Satoshi, YAMAGUCHI Mikiyo, EBISU Shigeyuki

    Vol. 49　p. 101-101　2006/10/11

  42. Antibacterial effects and physical properties of glass-ionomer cements containing chlorhexidine for the ART approach

    Yusuke Takahashi, Satoshi Imazato, Andrea V. Kaneshiro, Shigeyuki Ebisu, Jo E. Frencken, Franklin R. Tay

    DENTAL MATERIALS　Vol. 22　No. 7　p. 647-652　2006/07

  43. In vitro antibacterial effects of the dentin primer of Clearfil Protect Bond

    S Imazato, A Kuramoto, Y Takahashi, S Ebisu, MC Peters

    DENTAL MATERIALS　Vol. 22　No. 6　p. 527-532　2006/06

  44. Fracture resistance of pulpless teeth restored with post-cores and crowns

    M Hayashi, Y Takahashi, S Imazato, S Ebisu

    DENTAL MATERIALS　Vol. 22　No. 5　p. 477-485　2006/05

  45. Pulpal Reactions and in vivo Bonding Interface of Antibacterial Self-etching System Incorporating MDPB

    The Japanese Journal of Conservative Dentistry　Vol. 49 (4): 523-529　2006

  46. In Vitro Antibacterial Effects of the Dentin Primer of Clearfil Protect Bond

    Dent. Mater.　Vol. 22 (6): 527-532　2006

  47. 抗菌性モノマーMDPB配合セルフエッチングシステムの歯髄刺激性とin vivoにおける接着界面

    日本歯科保存学雑誌　Vol. 49 (4): 523-529　2006

  48. Immunohistochemical expression of Dentin Matrix Protein 1 during reparative dentinogenesis following cavity preparation

    KAWAHARA Takashi, TAKAHASHI Yusuke, TOYOSAWA Satoru, IMAZATO Satoshi, IMANISHI Hiromi, ITOH Munenori, TANAKA Syohei, EBISU Shigeyuki

    Vol. 47　p. 192-192　2004/10/18

  49. Influence of Resin Monomers on Growth of Oral Streptococci

    Y. Takahashi, S. Imazato, R.R.B. Russell, Y. Noiri, S. Ebisu

    Journal of Dental Research　Vol. 83　No. 4　p. 302-306　2004/04

    Publisher: SAGE Publications

  50. Influence of resin monomers on growth of oral streptococci

    Y Takahashi, S Imazato, RRB Russell, Y Noiri, S Ebisu

    JOURNAL OF DENTAL RESEARCH　Vol. 83　No. 4　p. 302-306　2004/04

  51. Clinical Evaluation of the Objectivity of Caries Removal Using a Caries Detector Dye

    IWAMI Y

    Japanese Jounal of Conservative Dentistry　Vol. 47　p. 716-722　2004

  52. う蝕検知液を用いたう蝕除去の客観性についての臨床的評価

    日本歯科保存学雑誌　2004

  53. Morphological Study of Bonding Interface of One-Step Adhesives to Root Dentin

    KANESHIRO Andrea V., IMAZATO Satoshi, KANEKO Tomoyuki, TAKAHASHI Yusuke, NOIRI Yuichiro, EBISU Shigeyuki

    Vol. 46　p. 52-52　2003/10/07

  54. SEM observation of bonding interface of one-step adhesive systems to root dentin.

    T. Kaneko, S. Imazato, A. V. Kaneshiro, Y. Takahashi, S. Ebisu

    JOURNAL OF DENTAL RESEARCH　Vol. 82　p. B119-B119　2003/06　Research paper, summary (international conference)

  55. Antibacterial effects and physical properties of glass-ionomer cements containing chlorhexicline for ART.

    Y. Takahashi, S. Imazato, T. Kaneko, K. Ishimura, S. Ebisu, J. E. Frencken, F. R. Tay

    JOURNAL OF DENTAL RESEARCH　Vol. 82　p. B137-B137　2003/06　Research paper, summary (international conference)

  56. う蝕による歯髄への感染

    クインテッセンス出版　2003

  57. SEM Evaluation of In Vivo Resin-Dentin Interface with Antibacterial Adhesive Systems Incorporating MDPB

    KANEKO T., IMAZATO S., NOIRI Y., TAKAHASHI Y., KANESHIRO A. V., EBISU S., TAY F. R.

    Vol. 19　No. 4　p. 382-382　2002/03/15

  58. Effects of resin monomer on oral bacterial growth

    TAKAHASHI Yusuke, KAWAI Keiji, EBISU Shigeyuki

    Vol. 43　p. 103-103　2000/03/21

Publications 9

  1. MTAアップデート : 生体材料としての現状と展望

    興地, 隆史, 高橋雄介

    ヒョーロン・パブリッシャーズ　2022/07

    ISBN: 9784864320726

  2. Pulp conservation using adhesive/functional materials

    Yusuke Takahashi, Mikako Hayashi

    2020/10

  3. 次世代の歯の治療 －歯髄・根尖歯周組織の再生－① バイオロジカル歯髄創傷治癒誘導② －MMPファミリー分子－

    高橋雄介

    歯界展望　2014/07　Scholarly book

  4. 歯内療法学専門用語集

    高橋雄介

    日本歯科保存学会、日本歯内療法学会　2013/06　Scholarly book

  5. Dental tissue inflammation and regeneration

    Takahashi Y, Cooper PR, Smith AJ

    Nova Science Publishers　2010/10　Scholarly book

  6. 保存修復学専門用語集

    恵比須繁之, 岩見行晃, 高橋雄介

    医歯薬出版　2009/03　Scholarly book

  7. 生命歯科医学のカッティングエッジ

    恵比須繁之, 今里聡, 竹重文雄, 林美加子, 野杁由一郎, 岩見行晃, 伊藤祥作, 高橋雄介, 薮根敏晃

    大阪大学出版会　2008/03　Scholarly book

  8. Fluoride ion released from glass-ionomer cement is responsible to inhibit the acid production of caries-related oral streptococci

    Nakajo K, Takahashi Y, Kiba W, Imazato S, Takahashi N

    Springer Japan　2007/06　Scholarly book

  9. う蝕による歯髄への感染

    高橋雄介

    クインテッセンス出版　2003/03　Scholarly book

Works 6

  1. 修復象牙質形成過程におけるマトリックスメタロプロテアーゼの局在および機能解析

    2009 -

  2. 修復象牙質形成における発現遺伝子のプロファイリング

    2008 -

  3. 修復象牙質形成における発現遺伝子のプロファイリング

    2007 -

  4. IL-6シグナルに潜むネガティブフィードバック機構の炎症性骨・歯根吸収への応用

    2006 -

  5. う蝕原性細菌表層におけるレジンモノマーの重合現象に関する多面的解析

    2006 -

  6. う蝕原性細菌表層におけるレジンモノマーの重合現象に関する多面的解析

    2005 -

Industrial Property Rights 3

  1. Peptides and associated components

    Yusuke Takahashi, Masakatsu Watanabe, Motoki Okamoto, Mikako Hayashi, Kei Kanie, Ryuji Katoh, Yuji Narita, Aika Ogata

    出願日:2021/07/07

  2. 象牙質-歯髄を再生させる新規直接覆髄材料

    岡本基岐, 高橋雄介, 林美加子, 蟹江慧, 加藤竜司, 緒方藍歌, 成田裕司, 荏原充宏, 宇都甲一郎

    出願日:2019/10

  3. 象牙質-歯髄を再生させる新規直接覆髄材料

    岡本基岐, 高橋雄介, 林美加子, 蟹江慧, 加藤竜司, 緒方藍歌, 成田裕司, 荏原充宏, 宇都甲一郎

    出願日:2018/10

Academic Activities 1

  1. 大阪大学大学院歯学研究科 第15回市民フォーラム「治せなかった病気が治る、最新歯科治療」

    大阪大学歯学研究科・大阪大学歯学部付属病院

    2017/12 -

Institutional Repository 3

Content Published in the University of Osaka Institutional Repository (OUKA)

  1. Effect of Heparan Sulfate on Vasculogenesis and Dentinogenesis of Dental Pulp Stem Cells

    Li Aonan, Sasaki Jun-Ichi, Huang Hailing, Abe Gabriela L., Inubushi Toshihiro, Takahashi Yusuke, Hayashi Mikako, Imazato Satoshi

    Journal of Endodontics　Vol. 50　No. 8　p. 1108-1116　2024/05/07

  2. Lithium-containing S-PRG fillers promoted the wound healing process of pulp tissues through activation of Wnt/β-catenin signaling pathway

    Ali Manahil, Okamoto Motoki, Komichi Shungo, Watanabe Masakatsu, Huang Hailing, Takahashi Yusuke, Hayashi Mikako

    The Journal of Osaka University Dental Society　Vol. 65　No. 2　p. 15-22　2021/06/30

  3. レジンモノマーと口腔細菌の増殖との関連性に関する研究

    高橋 雄介