keyword Macrophage，Rab32/Rab38，Autophagy，endothelial cell，Streptococcus pyogenes
Osaka University Graduate school of Frontier Biosciences phD
2011/04 - 2016/03
National Cheng Kung University The Institute of Basic Medical Sciences phD
2007/09 - 2014/07
Japanese Society of Bacteriology
The Japanese Biochemical Society
日本細胞生物
THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
Life sciences / Molecular biology / Rab32/Rab38
Life sciences / Molecular biology / VEGF
Life sciences / Functional biochemistry / Autophagy
Life sciences / Cell biology / Endothelial cell
Life sciences / Bacteriology / Streptococcus pyogenes
25th Osaka University School of Dentistry Yumikura Encouragement Award
Lu Shiou-Ling 2023/03
JSPS Fellowship Programs for Overseas Researchers
JSPS 2016/04
Capsule-deficient group A Streptococcus evades autophagy-mediated killing in macrophages
Yong-An Shi, Shiou-Ling Lu, Takeshi Noda, Cheng-Hsun Chiu, Chuan Chiang-Ni
mBio Vol. 15 No. 7 2024/07/17 Research paper (scientific journal)
Publisher: American Society for Microbiology
Rab32 and Rab38 maintain bone homeostasis by regulating intracellular traffic in osteoclasts
Cell Structure and Function 2023/10
Opposing roles of RUBCN isoforms in autophagy and memory B cell generation.
Chao-Yuan Tsai, Shuhei Sakakibara, Yu-Diao Kuan, Hiroko Omori, Maruwa Ali El Hussien, Daisuke Okuzaki, Shiou-Ling Lu, Takeshi Noda, Keisuke Tabata, Shuhei Nakamura, Tamotsu Yoshimori, Hitoshi Kikutani
Science signaling Vol. 16 No. 803 2023/09/19 Research paper (scientific journal)
Characterization of Rab32- and Rab38-positive lysosome-related organelles in osteoclasts and macrophages
Kazuya Noda, Shiou-Ling Lu, Siyu Chen, Kanako Tokuda, Yangjie Li, Feike Hao, Yoh Wada, Ge-Hong Sun-Wada, Shinya Murakami, Mitsunori Fukuda, Takashi Itoh, Takeshi Noda
Journal of Biological Chemistry Vol. 299 2023/08 Research paper (scientific journal)
Publisher: ASBMB
VEGF (vascular endothelial growth factor) provides antimicrobial effects via autophagy and lysosomal empowerment in endothelial cells
Shiou-Ling Lu, Takeshi Noda
Autophagy Reports Vol. 1 No. 1 p. 555-558 2022/12/31 Research paper (scientific journal)
Publisher: Informa UK Limited
VEGF-Mediated Augmentation of Autophagic and Lysosomal Activity in Endothelial Cells Defends against Intracellular Streptococcus pyogenes
Shiou-Ling Lu, Hiroko Omori, Yi Zhou, Yee-Shin Lin, Ching-Chuan Liu, Jiunn-Jong Wu, Takeshi Noda
mBio 2022/07/05 Research paper (scientific journal)
Erratum for Cheng et al., "Group A Streptococcus Induces LAPosomes via SLO/β1 Integrin/NOX2/ROS Pathway in Endothelial Cells That Are Ineffective in Bacterial Killing and Suppress Xenophagy"
Yi-Lin Cheng, Chih-Feng Kuo, Shiou-Ling Lu, Hiroko Omori, Ya-Na Wu, Cheng-Lu Hsieh, Takeshi Noda, Shang-Rung Wu, Robert Anderson, Chiou-Feng Lin, Chia-Ling Chen, Jiunn-Jong Wu, Yee-Shin Lin
mBio Vol. 12 No. 4 2021/08/31 Research paper (scientific journal)
Publisher: NLM (Medline)
Quercetin in Tartary Buckwheat Induces Autophagy against Protein Aggregations
Sumiko Ikari, Qiang Yang, Shiou-Ling Lu, Yuancai Liu, Feike Hao, Guoqiang Tong, Shiguang Lu, Takeshi Noda
Antioxidants Vol. 10 No. 8 p. 1217-1217 2021/07/29 Research paper (scientific journal)
Publisher: MDPI AG
Starvation-induced autophagy via calcium-dependent TFEB dephosphorylation is suppressed by Shigyakusan.
Sumiko Ikari, Shiou-Ling Lu, Feike Hao, Kenta Imai, Yasuhiro Araki, Yo-Hei Yamamoto, Chao-Yuan Tsai, Yumi Nishiyama, Nobukazu Shitan, Tamotsu Yoshimori, Takanobu Otomo, Takeshi Noda
PloS one Vol. 15 No. 3 2020 Research paper (scientific journal)
Nicotinamide Increases Intracellular NAD+ Content to Enhance Autophagy-Mediated Group A Streptococcal Clearance in Endothelial Cells.
Cheng-Lu Hsieh, Shu-Ying Hsieh, Hsuan-Min Huang, Shiou-Ling Lu, Hiroko Omori, Po-Xing Zheng, Yen-Ning Ho, Yi-Lin Cheng, Yee-Shin Lin, Chuan Chiang-Ni, Pei-Jane Tsai, Shu-Ying Wang, Ching-Chuan Liu, Takeshi Noda, Jiunn-Jong Wu
Frontiers in microbiology Vol. 11 p. 117-117 2020
Group A Streptococcus Induces LAPosomes via SLO/β1 Integrin/NOX2/ROS Pathway in Endothelial Cells That Are Ineffective in Bacterial Killing and Suppress Xenophagy.
Yi-Lin Cheng, Chih-Feng Kuo, Shiou-Ling Lu, Omori Hiroko, Ya-Na Wu, Cheng-Lu Hsieh, Takeshi Noda, Shang-Rung Wu, Robert Anderson, Chiou-Feng Lin, Chia-Ling Chen, Jiunn-Jong Wu, Yee-Shin Lin
mBio Vol. 10 No. 5 2019/10/01 Research paper (scientific journal)
The mechanism of bacterial replication in endothelial cells
Tsuyoshi Kawabata, Shiou-Ling Lu, Tamotsu Yoshimori
J-GLOBAL Vol. 70 No. 5 p. 532-536 2018/11 Research paper (scientific journal)
Galectin-3 Inhibits Galectin-8/Parkin-Mediated Ubiquitination of Group A Streptococcus
Yi-Lin Cheng, Yan-Wei Wu, Chih-Feng Kuo, Shiou-Ling Lu, Fu-Tong Liu, Robert Anderson, Chiou-Feng Lin, Yi-Ling Liu, Wan-Yu Wang, Ying-Da Chen, Po-Xing Zheng, Jiunn-Jong Wu, Yee-Shin Lin
MBIO Vol. 8 No. 4 2017/07 Research paper (scientific journal)
Endothelial cells are intrinsically defective in xenophagy of Streptococcus pyogenes
Shiou-Ling Lu, Tsuyoshi Kawabata, Yi-Lin Cheng, Hiroko Omori, Maho Hamasaki, Tatsuya Kusaba, Ryo Iwamoto, Hirokazu Arimoto, Takeshi Noda, Yee-Shin Lin, Tamotsu Yoshimori
PLOS PATHOGENS Vol. 13 No. 7 2017/07 Research paper (scientific journal)
Insufficient Acidification of Autophagosomes Facilitates Group A Streptococcus Survival and Growth in Endothelial Cells
Shiou-Ling Lu, Chih-Feng Kuo, Hao-Wen Chen, Yi-Shuan Yang, Ching-Chuan Liu, Robert Anderson, Jiunn-Jong Wu, Yee-Shin Lin
MBIO Vol. 6 No. 5 2015/09 Research paper (scientific journal)
Regulatory Role of GSK-3 beta on NF-kappa B, Nitric Oxide, and TNF-alpha in Group A Streptococcal Infection
Yu-Tzu Chang, Chia-Ling Chen, Chiou-Feng Lin, Shiou-Ling Lu, Miao-Huei Cheng, Chih-Feng Kuo, Yee-Shin Lin
MEDIATORS OF INFLAMMATION Vol. 2013 2013 Research paper (scientific journal)
Plasma kallistatin levels in patients with severe community-acquired pneumonia
Wei-Chieh Lin, Shiou-Ling Lu, Chiou-Feng Lin, Chang-Wen Chen, Lee Chao, Julie Chao, Yee-Shin Lin
CRITICAL CARE Vol. 17 No. 1 2013 Research paper (scientific journal)
Kallistatin modulates immune cells and confers anti-inflammatory response to protect mice from group A streptococcal infection.
Shiou-Ling Lu, Chiau-Yuang Tsai, Yueh-Hsia Luo, Chih-Feng Kuo, Wei-Chieh Lin, Yu-Tzu Chang, Jiunn-Jong Wu, Woei-Jer Chuang, Ching-Chuan Liu, Lee Chao, Julie Chao, Yee-Shin Lin
Antimicrobial Agents and Chemotherapy Vol. 57 p. 5366-5372 2013 Research paper (scientific journal)
Synergistic effects of streptolysin S and streptococcal pyrogenic exotoxin B on the mouse model of group A streptococcal infection
Chih-Hsin Hung, Nina Tsao, Yi-Fang Zeng, Shiou-Ling Lu, Chuan Chiang-Ni, Yee-Shin Lin, Jiunn-Jong Wu, Chih-Feng Kuo
MEDICAL MICROBIOLOGY AND IMMUNOLOGY Vol. 201 No. 3 p. 357-369 2012/08 Research paper (scientific journal)
Size-Dependent Attenuation of TLR9 Signaling by Gold Nanoparticles in Macrophages
Chiau-Yuang Tsai, Shiou-Ling Lu, Chia-Wen Hu, Chen-Sheng Yeh, Gwo-Bin Lee, Huan-Yao Lei
JOURNAL OF IMMUNOLOGY Vol. 188 No. 1 p. 68-76 2012/01 Research paper (scientific journal)
The emerging role of Rab proteins in osteoclast organelle biogenesis and function
Shiou-Ling Lu, Takeshi Noda
Biochemical Society Transactions Vol. 52 No. 6 p. 2469-2475 2024/12/19 Research paper (scientific journal)
Dextromethorphan Efficiently Increases Bactericidal Activity, Attenuates Inflammatory Responses, and Prevents Group A Streptococcal Sepsis
Ming-Han Li, Yueh-Hsia Luo, Chiou-Feng Lin, Yu-Tzu Chang, Shiou-Ling Lu, Chih-Feng Kuo, Jau-Shyong Hong, Yee-Shin Lin
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY Vol. 55 No. 3 p. 967-973 2011/03 Research paper (scientific journal)
Inhibition of group A streptococcal infection by Melaleuca alternifolia (tea tree) oil concentrate in the murine model
N. Tsao, C. -F. Kuo, H. -Y. Lei, S. -L. Lu, K. -J Huang
JOURNAL OF APPLIED MICROBIOLOGY Vol. 108 No. 3 p. 936-944 2010/03 Research paper (scientific journal)
The multiplication of invasive Streptococcus pyogenes in endothelial cell accompanies autophagy formation
Shiou-Ling Lu, Yee-Shin Lin
JOURNAL OF IMMUNOLOGY Vol. 184 2010/04 Research paper, summary (international conference)
Mitochondrial autophagy is carried out by microautophagy in macrophages
Lu Shiou-Ling
2024/11/06
Mitochondrial autophagy is carried out by microautophagy in macrophages
Lu Shiou-Ling
2024/10/17
Mitochondrial autophagy is carried out by microautophagy in macrophages
Lu Shiou-Ling
The 10th International Symposium on Autophagy 2022/10/24
VEGF-mediated antimicrobial effects in endothelial cells
Lu Shiou-Ling
The Molecular Biology Society of Japan 2019/12/03
Intrinsically insufficient xenophagy causes GAS growth in endothelial cells.
Lu Shiou-Ling, Tsuyoshi Kawabata, Hirokazu Arimoto, Tamotsu Yoshimori
JSPS A3 Foresight program: International A3 Foresight Symposium on Autophagy 2016/03
Messages of graduated student from Graduate School of Frontier Biosciences
Lu Shiou-Ling
2017/09
How does Taiwan’s woman survive in research field in Taiwan vs. in Japan?
Lu Shiou-Ling
JSPS Science Dialogue 2016/06
Hormonal mechanisms in the paraventricular nuclei associated with hyperalgesia in Parkinson's disease model rats
Yang Shengsen, Usami Nayuka, Lu Shiou-Ling, Oda Wakana, Maegawa Hiroharu, Niwa Hitoshi, Kudo Chiho
Biochemical and Biophysical Research Communications Vol. 744 2025/01/01
血管内皮増殖因子の新たな役割 : 殺菌作用増強効果の発見
Lu Shiou-Ling, 野田 健司
The Journal of Osaka University Dental Society Vol. 67 No. 2 p. 17-19 2023/06/30
The mechanism behind insufficient Streptococcus pyogenes clearance by autophagy in endothelial cells compared to epithelial cells.
Lu Shiou-Ling
