Plap-1 lineage tracing and single-cell transcriptomics reveal cellular dynamics in the periodontal ligament.

Tomoaki Iwayama, Mizuho Iwashita, Kazuya Miyashita, Hiromi Sakashita, Shuji Matsumoto, Kiwako Tomita, Phan Bhongsatiern, Tomomi Kitayama, Kentaro Ikegami, Takashi Shimbo, Katsuto Tamai, Masanori A Murayama, Shuhei Ogawa, Yoichiro Iwakura, Satoru Yamada, Lorin E Olson, Masahide Takedachi, Shinya Murakami

Development (Cambridge, England)　Vol. 149　No. 19　2022/10/01　Research paper (scientific journal)

Synthesized HMGB1 peptide prevents the progression of inflammation, steatosis, fibrosis, and tumor occurrence in a non-alcoholic steatohepatitis mouse model.

Yui Ishii, Atsunori Tsuchiya, Kazuki Natsui, Youhei Koseki, Nobutaka Takeda, Kei Tomiyoshi, Fusako Yamazaki, Yuki Yoshida, Takashi Shimbo, Katsuto Tamai, Shuji Terai

Hepatology research : the official journal of the Japan Society of Hepatology　2022/08/06　Research paper (scientific journal)

Single-cell transcriptome analysis of fractional CO2 laser efficiency in treating a mouse model of alopecia.

Kouichi Hasegawa, Takahiro Fujimoto, Chihiro Mita, Hidehiro Furumoto, Masako Inoue, Kentaro Ikegami, Tomomi Kitayama, Yukari Yamamoto, Takashi Shimbo, Takehiko Yamazaki, Katsuto Tamai

Lasers in surgery and medicine　2022/08/02　Research paper (scientific journal)

Successful hybrid grafting of autologous cultured epidermis carrying a revertant mutation and split mesh skin in a patient with recessive dystrophic epidermolysis bullosa

Atsushi Tanemura, Shiho Mori, Kyoko Tonomura, Kazunori Yokoi, Tomoyo Tanaka, Masukazu Inoie, Satoshi Takaki, Takashi Shimbo, Katsuto Tamai, Manabu Fujimoto

European journal of dermatology : EJD　Vol. 32　No. 3　p. 417-419　2022/05/01　Research paper (scientific journal)

Generation of a recessive dystrophic epidermolysis bullosa mouse model with patient-derived compound heterozygous mutations.

Satoshi Takaki, Takashi Shimbo, Kentaro Ikegami, Tomomi Kitayama, Yukari Yamamoto, Sho Yamazaki, Shiho Mori, Katsuto Tamai

Laboratory investigation; a journal of technical methods and pathology　Vol. 102　No. 6　p. 574-580　2022/02/12　Research paper (scientific journal)

Proteins That Read DNA Methylation.

Ke Liu, Takashi Shimbo, Xiaosheng Song, Paul A Wade, Jinrong Min

Advances in experimental medicine and biology　Vol. 1389　p. 269-293　2022　Research paper (scientific journal)

Synthesized HMGB1 peptide attenuates liver inflammation and suppresses fibrosis in mice.

Shunsuke Nojiri, Atsunori Tsuchiya, Kazuki Natsui, Suguru Takeuchi, Takayuki Watanabe, Yuichi Kojima, Yusuke Watanabe, Hiroteru Kamimura, Masahiro Ogawa, Satoko Motegi, Takahiro Iwasawa, Takeki Sato, Masaru Kumagai, Yui Ishii, Tomomi Kitayama, Yu-Tung Li, Yuya Ouchi, Takashi Shimbo, Masaaki Takamura, Katsuto Tamai, Shuji Terai

Inflammation and regeneration　Vol. 41　No. 1　p. 28-28　2021/09/27　Research paper (scientific journal)

単一細胞網羅的遺伝子発現解析に供するマウス軟骨細胞の単離方法の検討

石橋 恭太, 新保 敬史, 佐々木 英嗣, 宮下 和也, 北山 智美, 對馬 誉大, 石橋 恭之, 玉井 克人

日本整形外科学会雑誌　Vol. 95　No. 8　p. S1730-S1730　2021/08

Longitudinal Single-Cell Transcriptomics Reveals a Role for Serpina3n-Mediated Resolution of Inflammation in a Mouse Colitis Model.

Yen-Ting Ho, Takashi Shimbo, Edward Wijaya, Tomomi Kitayama, Satoshi Takaki, Kentaro Ikegami, Kazuya Miyashita, Yuya Ouchi, Eiichi Takaki, Ryoma Yamamoto, Yasufumi Kaneda, Katsuto Tamai

Cellular and molecular gastroenterology and hepatology　Vol. 12　No. 2　p. 547-566　2021/04/13　Research paper (scientific journal)

Recessive dystrophic epidermolysis bullosa with extensive transplantation of cultured epidermal autograft product after cardiopulmonary resuscitation: A case report.

Shiho Mori, Takashi Shimbo, Yuka Kimura, Mami Hayashi, Eiji Kiyohara, Miho Fukui, Miho Watanabe, Kazuhiko Bessho, Manabu Fujimoto, Katsuto Tamai

The Journal of dermatology　Vol. 48　No. 4　2021/04

Controlled induction of immune tolerance by mesenchymal stem cells transferred by maternal microchimerism

Sayuri Iwai, Aiko Okada, Kei Sasano, Masayuki Endo, Sho Yamazaki, Xin Wang, Takashi Shimbo, Takuji Tomimatsu, Tadashi Kimura, Katsuto Tamai

Biochemical and Biophysical Research Communications　Vol. 539　p. 83-88　2021/02　Research paper (scientific journal)

Contribution of PDGFRα lineage cells in adult mouse hematopoiesis.

Asaka Miura, Takashi Shimbo, Tomomi Kitayama, Yuya Ouchi, Sho Yamazaki, Mami Nishida, Eiichi Takaki, Ryoma Yamamoto, Edward Wijaya, Katsuto Tamai

Biochemical and biophysical research communications　Vol. 534　p. 186-192　2021/01/01　Research paper (scientific journal)

敗血症性心肺停止の蘇生後に胃瘻造設・自家培養表皮移植で著明回復を得た重症表皮水疱症の1例

森 志朋, 新保 敬史, 木村 優香, 林 真未, 清原 英司, 別所 一彦, 渡邊 美穂, 藤本 学, 玉井 克人

日本皮膚科学会雑誌　Vol. 130　No. 5　p. 1228-1228　2020/05

HMGB1ペプチドを用いた幹細胞血中動員によるマウス膝関節軟骨修復効果の検討

對馬 誉大, 佐々木 英嗣, 新保 敬史, 菊池 康, 玉井 克人, 石橋 恭之

日本整形外科学会雑誌　Vol. 93　No. 8　p. S1663-S1663　2019/09

再生誘導医薬HMGB1ペプチドを用いた間葉系幹細胞血中動員によるマウス膝関節軟骨修復効果

對馬 誉大, 佐々木 英嗣, 石橋 恭太, 山内 翔平, 新保 敬史, 菊池 康, 玉井 克人, 石橋 恭之

日本整形外科学会雑誌　Vol. 93　No. 8　p. S1663-S1663　2019/09

Cut-C: cleavage under tethered nuclease for conformational capture.

Takashi Shimbo, Machika Kawamura, Edward Wijaya, Eiichi Takaki, Yasufumi Kaneda, Katsuto Tamai

BMC genomics　Vol. 20　No. 1　p. 614-614　2019/07/29　Research paper (scientific journal)

Transcriptionally distinct mesenchymal stem/stromal cells circulate in fetus.

Okada A, Shimbo T, Endo M, Iwai S, Kitayama T, Ouchi Y, Yamamoto R, Takaki E, Yamazaki S, Nishida M, Wang X, Kikuchi Y, Tomimatsu T, Kaneda Y, Kimura T, Tamai K

Biochemical and biophysical research communications　Vol. 512　No. 2　p. 326-330　2019/04　Research paper (scientific journal)

DNA methylation in mice is influenced by genetics as well as sex and life experience.

Sara A Grimm, Takashi Shimbo, Motoki Takaku, James W Thomas, Scott Auerbach, Brian D Bennett, John R Bucher, Adam B Burkholder, Frank Day, Ying Du, Christopher G Duncan, John E French, Julie F Foley, Jianying Li, B Alex Merrick, Raymond R Tice, Tianyuan Wang, Xiaojiang Xu, Pierre R Bushel, David C Fargo, James C Mullikin, Paul A Wade

Nature communications　Vol. 10　No. 1　p. 305-305　2019/01/18　Research paper (scientific journal)

Chromatin accessibility identifies diversity in mesenchymal stem cells from different tissue origins.

Yen-Ting Ho, Takashi Shimbo, Edward Wijaya, Yuya Ouchi, Eiichi Takaki, Ryoma Yamamoto, Yasushi Kikuchi, Yasufumi Kaneda, Katsuto Tamai

Scientific reports　Vol. 8　No. 1　p. 17765-17765　2018/12/10　Research paper (scientific journal)

Chromatin accessibility identifies diversity in mesenchymal stem cells from different tissue origins.

Ho YT, Shimbo T, Wijaya E, Ouchi Y, Takaki E, Yamamoto R, Kikuchi Y, Kaneda Y, Tamai K

2018/12　Research paper (scientific journal)

CHD4 and the NuRD complex directly control cardiac sarcomere formation.

Wilczewski CM, Hepperla AJ, Shimbo T, Wasson L, Robbe ZL, Davis IJ, Wade PA, Conlon FL

Proceedings of the National Academy of Sciences of the United States of America　Vol. 115　No. 26　p. 6727-6732　2018/06

骨髄由来間葉系幹細胞は末梢血を介して炎症滑膜に集積する

佐々木 英嗣, 新保 敬史, 菊池 康, 石橋 恭之, 玉井 克人

日本整形外科学会雑誌　Vol. 91　No. 8　p. S1605-S1605　2017/08

DNA Methylation Changes in Tbx3 in a Mouse Model Exposed to Polybrominated Diphenyl Ethers

Takashi Shimbo, June K. Dunnick, Amy Brix, Deepak Mav, Ruchir Shah, John D. Roberts, Paul A. Wade

INTERNATIONAL JOURNAL OF TOXICOLOGY　Vol. 36　No. 3　p. 229-238　2017/05　Research paper (scientific journal)

High-quality ChIP-seq analysis of MBD3 in human breast cancer cells.

Shimbo T, Takaku M, Wade PA

Genomics data　Vol. 7　p. 173-174　2016/03

GATA3-dependent cellular reprogramming requires activation-domain dependent recruitment of a chromatin remodeler

Motoki Takaku, Sara A. Grimm, Takashi Shimbo, Lalith Perera, Roberta Menafra, Hendrik G. Stunnenberg, Trevor K. Archer, Shinichi Machida, Hitoshi Kurumizaka, Paul A. Wade

Genome Biology　Vol. 17　No. 1　2016/02/27　Research paper (scientific journal)

Proteins That Read DNA Methylation

Takashi Shimbo, Paul A. Wade

DNA METHYLTRANSFERASES - ROLE AND FUNCTION　Vol. 945　p. 303-320　2016　Research paper (scientific journal)

Genome-Wide Binding of MBD2 Reveals Strong Preference for Highly Methylated Loci

Roberta Menafra, Arie B. Brinkman, Filomena Matarese, Gianluigi Franci, Stefanie J. J. Bartels, Luan Nguyen, Takashi Shimbo, Paul A. Wade, Nina C. Hubner, Hendrik G. Stunnenberg

PLOS ONE　Vol. 9　No. 6　2014/06　Research paper (scientific journal)

Inhibition of histone binding by supramolecular hosts

Hillary F. Allen, Kevin D. Daze, Takashi Shimbo, Anne Lai, Catherine A. Musselman, Jennifer K. Sims, Paul A. Wade, Fraser Hof, Tatiana G. Kutateladze

BIOCHEMICAL JOURNAL　Vol. 459　No. 3　p. 505-512　2014/05　Research paper (scientific journal)

INO80 Facilitates Pluripotency Gene Activation in Embryonic Stem Cell Self-Renewal, Reprogramming, and Blastocyst Development

Li Wang, Ying Du, James M. Ward, Takashi Shimbo, Brad Lackford, Xiaofeng Zheng, Yi-liang Miao, Bingying Zhou, Leng Han, David C. Fargo, Raja Jothi, Carmen J. Williams, Paul A. Wade, Guang Hu

CELL STEM CELL　Vol. 14　No. 5　p. 575-591　2014/05　Research paper (scientific journal)

MBD3 Localizes at Promoters, Gene Bodies and Enhancers of Active Genes

Takashi Shimbo, Ying Du, Sara A. Grimm, Archana Dhasarathy, Deepak Mav, Ruchir R. Shah, Huidong Shi, Paul A. Wade

PLOS GENETICS　Vol. 9　No. 12　2013/12　Research paper (scientific journal)

13-Cis retinoic acid can enhance the antitumor activity of non-replicating Sendai virus particle against neuroblastoma

Motonari Nomura, Takashi Shimbo, Yasuhide Miyamoto, Masahiro Fukuzawa, Yasufumi Kaneda

CANCER SCIENCE　Vol. 104　No. 2　p. 238-244　2013/02　Research paper (scientific journal)

MBD3 localizes at promoters, gene bodies and enhancers of active genes.

Shimbo T, Du Y, Grimm SA, Dhasarathy A, Mav D, Shah RR, Shi H, Wade PA

PLoS genetics　Vol. 9　No. 12　2013

TRAIL and Noxa Are Selectively Upregulated in Prostate Cancer Cells Downstream of the RIG-I/MAVS Signaling Pathway by Nonreplicating Sendai Virus Particles

Taeko Matsushima-Miyagi, Koji Hatano, Motonari Nomura, Liu Li-Wen, Tomoyuki Nishikawa, Kotaro Saga, Takashi Shimbo, Yasufumi Kaneda

CLINICAL CANCER RESEARCH　Vol. 18　No. 22　p. 6271-6283　2012/11　Research paper (scientific journal)

Methyl-beta cyclodextrin alters the production and infectivity of Sendai virus

Hiroshi Fujita, Katsuto Tamai, Masako Kawachi, Kotaro Saga, Takashi Shimbo, Takehiko Yamazaki, Yasufumi Kaneda

ARCHIVES OF VIROLOGY　Vol. 156　No. 6　p. 995-1005　2011/06　Research paper (scientific journal)

Immunogene therapy using immunomodulating HVJ-E vector augments anti-tumor effects in murine malignant glioma

Masahide Matsuda, Keisuke Nimura, Takashi Shimbo, Toshimitsu Hamasaki, Tetsuya Yamamoto, Akira Matsumura, Yasufumi Kaneda

JOURNAL OF NEURO-ONCOLOGY　Vol. 103　No. 1　p. 19-31　2011/05　Research paper (scientific journal)

PDGFR alpha-positive cells in bone marrow are mobilized by high mobility group box 1 (HMGB1) to regenerate injured epithelia

Katsuto Tamai, Takehiko Yamazaki, Takenao Chino, Masaru Ishii, Satoru Otsuru, Yasushi Kikuchi, Shin Iinuma, Kotaro Saga, Keisuke Nimura, Takashi Shimbo, Noriko Umegaki, Ichiro Katayama, Jun-ichi Miyazaki, Junji Takeda, John A. McGrath, Jouni Uitto, Yasufumi Kaneda

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA　Vol. 108　No. 16　p. 6609-6614　2011/04　Research paper (scientific journal)

悪性黒色腫の新規血清腫瘍マーカーとしての抗BPAG1抗体(Serum anti-BPAG1 auto-antibody is a novel marker for human melanoma)

新保 敬史, 種村 篤, 玉井 克人, 片山 一郎, 金田 安史

日本癌学会総会記事　Vol. 69回　p. 76-77　2010/08

Serum Anti-BPAG1 Auto-Antibody Is a Novel Marker for Human Melanoma

Takashi Shimbo, Atsushi Tanemura, Takehiko Yamazaki, Katsuto Tamai, Ichiro Katayama, Yasufumi Kaneda

PLOS ONE　Vol. 5　No. 5　2010/05　Research paper (scientific journal)

Sterile alpha motif containing domain 9 is involved in death signaling of malignant glioma treated with inactivated Sendai virus particle (HVJ-E) or type I interferon

Masahiko Tanaka, Takashi Shimbo, Yasushi Kikuchi, Masahide Matsuda, Yasufumi Kaneda

INTERNATIONAL JOURNAL OF CANCER　Vol. 126　No. 8　p. 1982-1991　2010/04　Research paper (scientific journal)

Functional modification of Sendai virus by siRNA

Kotaro Saga, Katsuto Tamai, Masako Kawachi, Takashi Shimbo, Hiroshi Fujita, Takehiko Yamazaki, Yasufumi Kaneda

JOURNAL OF BIOTECHNOLOGY　Vol. 133　No. 3　p. 386-394　2008/02　Research paper (scientific journal)

Development of a transferrin receptor-targeting HVXE vector

Takashi Shimbo, Masako Kawachi, Kotaro Saga, Hiroshi Fujita, Takehiko Yamazaki, Katsuto Tanial, Yasufunii Kaneda

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS　Vol. 364　No. 3　p. 423-428　2007/12　Research paper (scientific journal)

Development of tissue-targeting hemagglutinating virus of Japan envelope vector for successful delivery of therapeutic gene to mouse skin

Masako Kawachi, Katsuto Tamai', Kotaro Saga, Takehiko Yamazaki, Hiroshi Fujita, Takashi Shimbo, Yasushi Kikuchi, Keisuke Nimura, Koji Nishifuji, Masayuki Amagai, Jouni Uitto, Yasufumi Kaneda

HUMAN GENE THERAPY　Vol. 18　No. 10　p. 881-894　2007/10　Research paper (scientific journal)