SARS-CoV-2 papain-like protease inhibits ISGylation of the viral nucleocapsid protein to evade host anti-viral immunity.

Aulia Fitri Rhamadianti, Takayuki Abe, Tomohisa Tanaka, Chikako Ono, Hisashi Katayama, Yoshiteru Makino, Lin Deng, Chieko Matsui, Kohji Moriishi, Fumi Shima, Yoshiharu Matsuura, Ikuo Shoji

Journal of virology　Vol. 98　No. 9　2024/09/17　Research paper (scientific journal)

Regulation viral RNA transcription and replication by higher-order RNA structures within the nsp1 coding region of MERS coronavirus.

Yutaka Terada, Sodbayasgalan Amarbayasgalan, Yoshiharu Matsuura, Wataru Kamitani

Scientific reports　Vol. 14　No. 1　p. 19594-19594　2024/08/23　Research paper (scientific journal)

Importin-7-dependent nuclear translocation of the Flavivirus core protein is required for infectious virus production.

Yumi Itoh, Yoichi Miyamoto, Makoto Tokunaga, Tatsuya Suzuki, Akira Takada, Akinori Ninomiya, Tomomi Hishinuma, Mami Matsuda, Yoshihiro Yoneda, Masahiro Oka, Ryosuke Suzuki, Yoshiharu Matsuura, Toru Okamoto

PLoS pathogens　Vol. 20　No. 8　2024/08　Research paper (scientific journal)

Enterovirus 3A protein disrupts endoplasmic reticulum homeostasis through interaction with GBF1.

Junki Hirano, Tsuyoshi Hayashi, Kouichi Kitamura, Yorihiro Nishimura, Hiroyuki Shimizu, Toru Okamoto, Kazuma Okada, Kentaro Uemura, Ming Te Yeh, Chikako Ono, Shuhei Taguwa, Masamichi Muramatsu, Yoshiharu Matsuura

Journal of virology　Vol. 98　No. 7　2024/07/23　Research paper (scientific journal)

Adjuvant-free parenterally injectable vaccine platform that harnesses previously induced IgG as an antigen delivery carrier

Atsushi Kawai, Haruki Hirata, Nagisa Tokunoh, Chikako Ono, Yoshiharu Matsuura, Toshiro Hirai, Yasuo Yoshioka

Biochemical and Biophysical Research Communications　Vol. 711　2024/06/04　Research paper (scientific journal)

JAK inhibition during the early phase of SARS-CoV-2 infection worsens kidney injury by suppressing endogenous antiviral activity in mice.

Hibiki Sakai, Hiroyasu Kamuro, Nagisa Tokunoh, Takeshi Izawa, Shigeyuki Tamiya, Ayaha Yamamoto, Shota Tanaka, Daisuke Okuzaki, Chikako Ono, Yoshiharu Matsuura, Yoshiaki Okada, Yasuo Yoshioka, Yasushi Fujio, Masanori Obana

American journal of physiology. Renal physiology　Vol. 326　No. 6　p. F931-F941-F941　2024/06/01　Research paper (scientific journal)

Akaluc bioluminescence offers superior sensitivity to track in vivo dynamics of SARS-CoV-2 infection.

Tomokazu Tamura, Hayato Ito, Shiho Torii, Lei Wang, Rigel Suzuki, Shuhei Tsujino, Akifumi Kamiyama, Yoshitaka Oda, Masumi Tsuda, Yuhei Morioka, Saori Suzuki, Kotaro Shirakawa, Kei Sato, Kumiko Yoshimatsu, Yoshiharu Matsuura, Satoshi Iwano, Shinya Tanaka, Takasuke Fukuhara

iScience　Vol. 27　No. 5　p. 109647-109647　2024/05/17　Research paper (scientific journal)

Genes involved in the limited spread of SARS-CoV-2 in the lower respiratory airways of hamsters may be associated with adaptive evolution

Kosuke Takada, Yasuko Orba, Yurie Kida, Jiaqi Wu, Chikako Ono, Yoshiharu Matsuura, So Nakagawa, Hirofumi Sawa, Tokiko Watanabe

Journal of Virology　Vol. 98　No. 5　2024/05　Research paper (scientific journal)

Vero cell-adapted SARS-CoV-2 strain shows increased viral growth through furin-mediated efficient spike cleavage.

Shohei Minami, Tomohiro Kotaki, Yusuke Sakai, Shinya Okamura, Shiho Torii, Chikako Ono, Daisuke Motooka, Rina Hamajima, Ryotaro Nouda, Jeffery A Nurdin, Moeko Yamasaki, Yuta Kanai, Hirotaka Ebina, Yusuke Maeda, Toru Okamoto, Taro Tachibana, Yoshiharu Matsuura, Takeshi Kobayashi

Microbiology spectrum　Vol. 12　No. 4　2024/02/28　Research paper (scientific journal)

Characterization of a neutralizing antibody that recognizes a loop region adjacent to the receptor-binding interface of the SARS-CoV-2 spike receptor-binding domain.

Itsuki Anzai, Junso Fujita, Chikako Ono, Yoichiro Kosaka, Yuki Miyamoto, Shintaro Shichinohe, Kosuke Takada, Shiho Torii, Shuhei Taguwa, Koichiro Suzuki, Fumiaki Makino, Tadahiro Kajita, Tsuyoshi Inoue, Keiichi Namba, Tokiko Watanabe, Yoshiharu Matsuura

Microbiology spectrum　Vol. 12　No. 4　2024/02/28　Research paper (scientific journal)

BCR, not TCR, repertoire diversity is associated with favorable COVID-19 prognosis.

Faith Jessica Paran, Rieko Oyama, Abdullah Khasawneh, Tomohiko Ai, Hendra Saputra Ismanto, Aalaa Alrahman Sherif, Dianita Susilo Saputri, Chikako Ono, Mizue Saita, Satomi Takei, Yuki Horiuchi, Ken Yagi, Yoshiharu Matsuura, Yasushi Okazaki, Kazuhisa Takahashi, Daron M Standley, Yoko Tabe, Toshio Naito

Frontiers in immunology　Vol. 15　p. 1405013-1405013　2024　Research paper (scientific journal)

Amino acid catabolite markers for early prognostication of pneumonia in patients with COVID-19.

Rae Maeda, Natsumi Seki, Yoshifumi Uwamino, Masatoshi Wakui, Yu Nakagama, Yasutoshi Kido, Miwa Sasai, Shu Taira, Naoya Toriu, Masahiro Yamamoto, Yoshiharu Matsuura, Jun Uchiyama, Genki Yamaguchi, Makoto Hirakawa, Yun-Gi Kim, Masayo Mishima, Motoko Yanagita, Makoto Suematsu, Yuki Sugiura

Nature communications　Vol. 14　No. 1　p. 8469-8469　2023/12/20　Research paper (scientific journal)

Enhancement of SARS-CoV-2 Infection via Crosslinking of Adjacent Spike Proteins by N-Terminal Domain-Targeting Antibodies.

Tina Lusiany, Tohru Terada, Jun-Ichi Kishikawa, Mika Hirose, David Virya Chen, Fuminori Sugihara, Hendra Saputra Ismanto, Floris J van Eerden, Songling Li, Takayuki Kato, Hisashi Arase, Matsuura Yoshiharu, Masato Okada, Daron M Standley

Viruses　Vol. 15　No. 12　2023/12/13　Research paper (scientific journal)

Intranasal immunization with an RBD-hemagglutinin fusion protein harnesses preexisting immunity to enhance antigen-specific responses.

Atsushi Kawai, Nagisa Tokunoh, Eigo Kawahara, Shigeyuki Tamiya, Shinya Okamura, Chikako Ono, Jessica Anindita, Hiroki Tanaka, Hidetaka Akita, Sho Yamasaki, Jun Kunisawa, Toru Okamoto, Yoshiharu Matsuura, Toshiro Hirai, Yasuo Yoshioka

The Journal of clinical investigation　Vol. 133　No. 23　2023/12/01　Research paper (scientific journal)

2-thiouridine is a broad-spectrum antiviral nucleoside analogue against positive-strand RNA viruses.

Kentaro Uemura, Haruaki Nobori, Akihiko Sato, Shinsuke Toba, Shinji Kusakabe, Michihito Sasaki, Koshiro Tabata, Keita Matsuno, Naoyoshi Maeda, Shiori Ito, Mayu Tanaka, Yuki Anraku, Shunsuke Kita, Mayumi Ishii, Kayoko Kanamitsu, Yasuko Orba, Yoshiharu Matsuura, William W Hall, Hirofumi Sawa, Hiroshi Kida, Akira Matsuda, Katsumi Maenaka

Proceedings of the National Academy of Sciences of the United States of America　Vol. 120　No. 42　2023/10/17　Research paper (scientific journal)

Oxidative stress sensor Keap1 recognizes HBx protein to activate the Nrf2/ARE signaling pathway, thereby inhibiting hepatitis B virus replication.

Adi Ariffianto, Lin Deng, Takayuki Abe, Chieko Matsui, Masahiko Ito, Akihide Ryo, Hussein Hassan Aly, Koichi Watashi, Tetsuro Suzuki, Masashi Mizokami, Yoshiharu Matsuura, Ikuo Shoji

Journal of virology　Vol. 97　No. 10　2023/10/06　Research paper (scientific journal)

Electrolyzed hypochlorous acid water exhibits potent disinfectant activity against various viruses through irreversible protein aggregation.

Rahmi Dianty, Junki Hirano, Itsuki Anzai, Yuta Kanai, Tsuyoshi Hayashi, Masae Morimoto, Chikako Kataoka-Nakamura, Sakura Kobayashi, Kentaro Uemura, Chikako Ono, Tokiko Watanabe, Takeshi Kobayashi, Kosuke Murakami, Kenji Kikuchi, Kunimoto Hotta, Toshikazu Yoshikawa, Shuhei Taguwa, Yoshiharu Matsuura

Frontiers in microbiology　Vol. 14　p. 1284274-1284274　2023/10/01　Research paper (scientific journal)

Trick-or-Trap: Extracellular Vesicles and Viral Transmission.

Juan-Vicente Bou, Shuhei Taguwa, Yoshiharu Matsuura

Vaccines　Vol. 11　No. 10　2023/09/27　Research paper (scientific journal)

A nasal vaccine with inactivated whole-virion elicits protective mucosal immunity against SARS-CoV-2 in mice.

Nagisa Tokunoh, Shigeyuki Tamiya, Masato Watanabe, Toru Okamoto, Jessica Anindita, Hiroki Tanaka, Chikako Ono, Toshiro Hirai, Hidetaka Akita, Yoshiharu Matsuura, Yasuo Yoshioka

Frontiers in immunology　Vol. 14　p. 1224634-1224634　2023/08/31　Research paper (scientific journal)

An inhaled ACE2 decoy confers protection against SARS-CoV-2 infection in preclinical models.

Emiko Urano, Yumi Itoh, Tatsuya Suzuki, Takanori Sasaki, Jun-Ichi Kishikawa, Kanako Akamatsu, Yusuke Higuchi, Yusuke Sakai, Tomotaka Okamura, Shuya Mitoma, Fuminori Sugihara, Akira Takada, Mari Kimura, Shuto Nakao, Mika Hirose, Tadahiro Sasaki, Ritsuko Koketsu, Shunya Tsuji, Shota Yanagida, Tatsuo Shioda, Eiji Hara, Satoaki Matoba, Yoshiharu Matsuura, Yasunari Kanda, Hisashi Arase, Masato Okada, Junichi Takagi, Takayuki Kato, Atsushi Hoshino, Yasuhiro Yasutomi, Akatsuki Saito, Toru Okamoto

Science translational medicine　Vol. 15　No. 711　2023/08/30　Research paper (scientific journal)

Inhibitors of cannabinoid receptor 1 suppress the cellular entry of Lujo virus.

Miyuki Kimura, Risa Matsuoka, Satoshi Taniguchi, Junki Maruyama, Slobodan Paessler, Saori Oka, Atsushi Yamashita, Takasuke Fukuhara, Yoshiharu Matsuura, Hideki Tani

Virology　Vol. 587　p. 109867-109867　2023/08/10　Research paper (scientific journal)

Hepatitis C Virus Disrupts Annexin 5-Mediated Occludin Integrity through Downregulation of Protein Kinase Cα (PKCα) and PKCη Expression, Thereby Promoting Viral Propagation.

Takayuki Abe, Yuki Marutani, Lin Deng, Chieko Matsui, Masayoshi Fukasawa, Ryosuke Suzuki, Takaji Wakita, Yoshiharu Matsuura, Ikuo Shoji

Journal of virology　Vol. 97　No. 6　2023/06/29　Research paper (scientific journal)

SARS-CoV-2 Neutralization Assay System using Pseudo-lentivirus

Anastasia Armimi, Afina Firdaus Syuaib, Katherine Vanya, Marselina Irasonia Tan, Dessy Natalia, David Virya Chen, Chikako Ono, Yoshiharu Matsuura, Anita Artarini

Indonesian Biomedical Journal　Vol. 15　No. 2　p. 179-184　2023/04　Research paper (scientific journal)

Neutralizing Antibody Response of the Wild-Type/Omicron BA.1 Bivalent Vaccine as the Second Booster Dose against Omicron BA.2 and BA.5.

Hitoshi Kawasuji, Yoshitomo Morinaga, Hideki Tani, Yumiko Saga, Hiroshi Yamada, Yoshihiro Yoshida, Yusuke Takegoshi, Makito Kaneda, Yushi Murai, Kou Kimoto, Akitoshi Ueno, Yuki Miyajima, Kentaro Nagaoka, Chikako Ono, Yoshiharu Matsuura, Hideki Niimi, Yoshihiro Yamamoto

Microbiology spectrum　Vol. 11　No. 2　2023/03/22　Research paper (scientific journal)

Genomic diversity of SARS-CoV-2 can be accelerated by mutations in the nsp14 gene.

Kosuke Takada, Mahoko Takahashi Ueda, Shintaro Shichinohe, Yurie Kida, Chikako Ono, Yoshiharu Matsuura, Tokiko Watanabe, So Nakagawa

iScience　Vol. 26　No. 3　p. 106210-106210　2023/03/17　Research paper (scientific journal)

HBV with precore and basal core promoter mutations exhibits a high replication phenotype and causes ER stress-mediated cell death in humanized liver chimeric mice.

Takuro Uchida, Michio Imamura, C Nelson Hayes, Yosuke Suehiro, Yuji Teraoka, Kazuki Ohya, Hiroshi Aikata, Hiromi Abe-Chayama, Yuji Ishida, Chise Tateno, Yuichi Hara, Keisuke Hino, Toru Okamoto, Yoshiharu Matsuura, Hideki Aizaki, Kenjiro Wake, Michinori Kohara, T Jake Liang, Shiro Oka, Kazuaki Chayama

Hepatology (Baltimore, Md.)　Vol. 78　No. 3　p. 929-942　2023/03/13　Research paper (scientific journal)

Increased flexibility of the SARS-CoV-2 RNA-binding site causes resistance to remdesivir.

Shiho Torii, Kwang Su Kim, Jun Koseki, Rigel Suzuki, Shoya Iwanami, Yasuhisa Fujita, Yong Dam Jeong, Jumpei Ito, Hiroyuki Asakura, Mami Nagashima, Kenji Sadamasu, Kazuhisa Yoshimura, Kei Sato, Yoshiharu Matsuura, Teppei Shimamura, Shingo Iwami, Takasuke Fukuhara

PLoS pathogens　Vol. 19　No. 3　2023/03/01　Research paper (scientific journal)

Epoxidized graphene grid for highly efficient high-resolution cryoEM structural analysis.

Junso Fujita, Fumiaki Makino, Haruyasu Asahara, Maiko Moriguchi, Shota Kumano, Itsuki Anzai, Jun-Ichi Kishikawa, Yoshiharu Matsuura, Takayuki Kato, Keiichi Namba, Tsuyoshi Inoue

Scientific reports　Vol. 13　No. 1　p. 2279-2279　2023/02/08　Research paper (scientific journal)

Antibody feedback contributes to facilitating the development of Omicron-reactive memory B cells in SARS-CoV-2 mRNA vaccinees.

Takeshi Inoue, Ryo Shinnakasu, Chie Kawai, Hiromi Yamamoto, Shuhei Sakakibara, Chikako Ono, Yumi Itoh, Tommy Terooatea, Kazuo Yamashita, Toru Okamoto, Noritaka Hashii, Akiko Ishii-Watabe, Noah S Butler, Yoshiharu Matsuura, Hisatake Matsumoto, Shinya Otsuka, Kei Hiraoka, Takanori Teshima, Masaaki Murakami, Tomohiro Kurosaki

The Journal of experimental medicine　Vol. 220　No. 2　2023/02/06　Research paper (scientific journal)

Upregulation of Robo4 expression by SMAD signaling suppresses vascular permeability and mortality in endotoxemia and COVID-19 models

Maaya Morita, Aki Yoneda, Nagisa Tokunoh, Tatsumi Masaki, Keisuke Shirakura, Mayumi Kinoshita, Rina Hashimoto, Naoya Shigesada, Junya Takahashi, Masashi Tachibana, Shota Tanaka, Masanori Obana, Nobumasa Hino, Masahito Ikawa, Kazutake Tsujikawa, Chikako Ono, Yoshiharu Matsuura, Hiroyasu Kidoya, Nobuyuki Takakura, Yoshiaki Kubota, Takefumi Doi, Kazuo Takayama, Yasuo Yoshioka, Yasushi Fujio, Yoshiaki Okada

Proceedings of the National Academy of Sciences　Vol. 120　No. 3　2023/01/17　Research paper (scientific journal)

変異型SARS-CoV-2 pseudovirusの作出ならびに中和抗体評価系の構築

鈴木 孝一朗, 小野 慎子, 朴 貞玉, 高橋 美恵, 川崎 淳, 松浦 善治

日本臨床微生物学会雑誌　Vol. 33　No. Suppl.1　p. 245-245　2022/12

変異型SARS-CoV-2 pseudovirusの作出ならびに中和抗体評価系の構築

鈴木 孝一朗, 小野 慎子, 朴 貞玉, 高橋 美恵, 川崎 淳, 松浦 善治

日本臨床微生物学会雑誌　Vol. 33　No. Suppl.1　p. 245-245　2022/12　Research paper (bulletin of university, research institution)

Past, present and future of infectious diseases

Yoshiharu Matsuura

Drug Delivery System　Vol. 37　No. 5　p. 372-376　2022/11/25　Research paper (scientific journal)

Human antibody recognition and neutralization mode on the NTD and RBD domains of SARS-CoV-2 spike protein.

Ryota Otsubo, Takeharu Minamitani, Kouji Kobiyama, Junso Fujita, Toshihiro Ito, Shiori Ueno, Itsuki Anzai, Hiroki Tanino, Hiroshi Aoyama, Yoshiharu Matsuura, Keiichi Namba, Ken-Ichi Imadome, Ken J Ishii, Kouhei Tsumoto, Wataru Kamitani, Teruhito Yasui

Scientific reports　Vol. 12　No. 1　p. 20120-20120　2022/11/22　Research paper (scientific journal)

Versatile live-attenuated SARS-CoV-2 vaccine platform applicable to variants induces protective immunity.

Akiho Yoshida, Shinya Okamura, Shiho Torii, Sayuri Komatsu, Paola Miyazato, Hitomi Sasaki, Shiori Ueno, Hidehiko Suzuki, Wataru Kamitani, Chikako Ono, Yoshiharu Matsuura, Shiro Takekawa, Koichi Yamanishi, Hirotaka Ebina

iScience　Vol. 25　No. 11　p. 105412-105412　2022/11/18　Research paper (scientific journal)

Membrane Sphingomyelin in Host Cells Is Essential for Nucleocapsid Penetration into the Cytoplasm after Hemifusion during Rubella Virus Entry.

Yoshio Mori, Masafumi Sakata, Shota Sakai, Toru Okamoto, Yuichiro Nakatsu, Shuhei Taguwa, Noriyuki Otsuki, Yusuke Maeda, Kentaro Hanada, Yoshiharu Matsuura, Makoto Takeda

mBio　Vol. 13　No. 6　2022/11/08　Research paper (scientific journal)

Establishment and clinical application of SARS-CoV-2 catch column.

Yoshitaka Isaka, Taku Yoshiya, Chikako Ono, Akinori Uchiyama, Haruhiko Hirata, Shigeto Hamaguchi, Satoshi Kutsuna, Yoshitsugu Takabatake, Ryotaro Saita, Tomomi Yamada, Atsushi Takahashi, Masaya Yamato, Yukie Nohara, Shugo Tsuda, Itsuki Anzai, Tomonori Kimura, Yoshito Takeda, Kazunori Tomono, Yoshiharu Matsuura

Clinical and experimental nephrology　Vol. 27　No. 3　p. 1-9　2022/11/07　Research paper (scientific journal)

Repeated Intravaginal Inoculation of Zika Virus Protects Cynomolgus Monkeys from Subcutaneous Superchallenge

Maya Shofa, Tomotaka Okamura, Emiko Urano, Yoshiharu Matsuura, Yasuhiro Yasutomi, Akatsuki Saito

International Journal of Molecular Sciences　Vol. 23　No. 22　2022/11/01　Research paper (scientific journal)

Engineered flavivirus vaccines control induction of crossreactive infection-enhancing and -neutralizing antibodies.

Atsushi Yamanaka, Pimploy Rattanaamnuaychai, Mami Matsuda, Ryosuke Suzuki, Yoshiharu Matsuura, Masashi Tatsumi, Eiji Konishi

Vaccine　Vol. 40　No. 42　p. 6004-6011　2022/10/06　Research paper (scientific journal)

SARS-CoV-2 disrupts respiratory vascular barriers by suppressing Claudin-5 expression.

Rina Hashimoto, Junya Takahashi, Keisuke Shirakura, Risa Funatsu, Kaori Kosugi, Sayaka Deguchi, Masaki Yamamoto, Yugo Tsunoda, Maaya Morita, Kosuke Muraoka, Masato Tanaka, Tomoaki Kanbara, Shota Tanaka, Shigeyuki Tamiya, Nagisa Tokunoh, Atsushi Kawai, Masahito Ikawa, Chikako Ono, Keisuke Tachibana, Masuo Kondoh, Masanori Obana, Yoshiharu Matsuura, Akihiro Ohsumi, Takeshi Noda, Takuya Yamamoto, Yasuo Yoshioka, Yu-Suke Torisawa, Hiroshi Date, Yasushi Fujio, Miki Nagao, Kazuo Takayama, Yoshiaki Okada

Science advances　Vol. 8　No. 38　2022/09/23　Research paper (scientific journal)

SARS-CoV-2 ORF8 is a viral cytokine regulating immune responses.

Masako Kohyama, Tatsuya Suzuki, Wataru Nakai, Chikako Ono, Sumiko Matsuoka, Koichi Iwatani, Yafei Liu, Yusuke Sakai, Atsushi Nakagawa, Keisuke Tomii, Koichiro Ohmura, Masato Okada, Yoshiharu Matsuura, Shiro Ohshima, Yusuke Maeda, Toru Okamoto, Hisashi Arase

International immunology　Vol. 35　No. 1　p. 43-52　2022/09/02　Research paper (scientific journal)

Effectiveness of the third dose of BNT162b2 vaccine on neutralizing Omicron variant in the Japanese population.

Hitoshi Kawasuji, Yoshitomo Morinaga, Hideki Tani, Yumiko Saga, Makito Kaneda, Yushi Murai, Akitoshi Ueno, Yuki Miyajima, Yasutaka Fukui, Kentaro Nagaoka, Chikako Ono, Yoshiharu Matsuura, Hideki Niimi, Yoshihiro Yamamoto

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy　Vol. 28　No. 9　p. 1273-1278　2022/09/01　Research paper (scientific journal)

Immune response induced in rodents by anti-CoVid19 plasmid DNA vaccine via pyro-drive jet injector inoculation.

Tomoyuki Nishikawa, Chin Yang Chang, Jiayu A Tai, Hiroki Hayashi, Jiao Sun, Shiho Torii, Chikako Ono, Yoshiharu Matsuura, Ryoko Ide, Junichi Mineno, Miwa Sasai, Masahiro Yamamoto, Hironori Nakagami, Kunihiko Yamashita

Immunological medicine　Vol. 45　No. 4　p. 1-14　2022/08/24　Research paper (scientific journal)

Establishment of Neutralizing Monoclonal Antibodies Against Severe Acute Respiratory Syndrome Coronavirus 2 by the Screening with Exosomes Expressing the Viral Spike Protein.

Chihiro Okada, Etsuko Ikeda-Ishizaka, Chikako Ono, Yoshiharu Matsuura, Hikaru Sonoda

Monoclonal antibodies in immunodiagnosis and immunotherapy　Vol. 41　No. 4　p. 173-180　2022/08/01　Research paper (scientific journal)

Hepatitis C virus NS5A protein promotes the lysosomal degradation of diacylglycerol O-acyltransferase 1 (DGAT1) via endosomal microautophagy

Putu Yuliandari, Chieko Matsui, Lin Deng, Takayuki Abe, Hiroyuki Mori, Shuhei Taguwa, Chikako Ono, Takasuke Fukuhara, Yoshiharu Matsuura, Ikuo Shoji

Autophagy Reports　Vol. 1　No. 1　p. 264-285　2022/07/22　Research paper (scientific journal)

A panel of nanobodies recognizing conserved hidden clefts of all SARS-CoV-2 spike variants including Omicron.

Ryota Maeda, Junso Fujita, Yoshinobu Konishi, Yasuhiro Kazuma, Hiroyuki Yamazaki, Itsuki Anzai, Tokiko Watanabe, Keishi Yamaguchi, Kazuki Kasai, Kayoko Nagata, Yutaro Yamaoka, Kei Miyakawa, Akihide Ryo, Kotaro Shirakawa, Kei Sato, Fumiaki Makino, Yoshiharu Matsuura, Tsuyoshi Inoue, Akihiro Imura, Keiichi Namba, Akifumi Takaori-Kondo

Communications biology　Vol. 5　No. 1　p. 669-669　2022/07/06　Research paper (scientific journal)

The nonstructural p17 protein of a fusogenic bat-borne reovirus regulates viral replication in virus species- and host-specific manners

Ryotaro Nouda, Takahiro Kawagishi, Yuta Kanai, Masayuki Shimojima, Masayuki Saijo, Yoshiharu Matsuura, Takeshi Kobayashi

PLOS Pathogens　Vol. 18　No. 6　p. e1010553-e1010553　2022/06/02　Research paper (scientific journal)

The nonstructural p17 protein of a fusogenic bat-borne reovirus regulates viral replication in virus species- and host-specific manners.

Ryotaro Nouda, Takahiro Kawagishi, Yuta Kanai, Masayuki Shimojima, Masayuki Saijo, Yoshiharu Matsuura, Takeshi Kobayashi

PLoS pathogens　Vol. 18　No. 6　2022/06/01　Research paper (scientific journal)

Secretory glycoprotein NS1 plays a crucial role in the particle formation of flaviviruses.

Tomokazu Tamura, Shiho Torii, Kentaro Kajiwara, Itsuki Anzai, Yoichiro Fujioka, Kisho Noda, Shuhei Taguwa, Yuhei Morioka, Rigel Suzuki, Yuzy Fauzyah, Chikako Ono, Yusuke Ohba, Masato Okada, Takasuke Fukuhara, Yoshiharu Matsuura

PLoS pathogens　Vol. 18　No. 6　2022/06/01　Research paper (scientific journal)

Effectiveness of the third dose of BNT162b2 vaccine on neutralizing Omicron variant in the Japanese population

Hitoshi Kawasuji, Yoshitomo Morinaga, Hideki Tani, Yumiko Saga, Makito Kaneda, Yushi Murai, Akitoshi Ueno, Yuki Miyajima, Yasutaka Fukui, Kentaro Nagaoka, Chikako Ono, Yoshiharu Matsuura, Hideki Niimi, Yoshihiro Yamamoto

Journal of Infection and Chemotherapy　Vol. 28　No. 9　p. 1273-1278　2022/06　Research paper (scientific journal)

Preclinical study of a DNA vaccine targeting SARS-CoV-2.

Hiroki Hayashi, Jiao Sun, Yuka Yanagida, Takako Otera, Ritsuko Kubota-Koketsu, Tatsuo Shioda, Chikako Ono, Yoshiharu Matsuura, Hisashi Arase, Shota Yoshida, Ryo Nakamaru, Nan Ju, Ryoko Ide, Akiko Tenma, Sotaro Kawabata, Takako Ehara, Makoto Sakaguchi, Hideki Tomioka, Munehisa Shimamura, Sachiko Okamoto, Yasunori Amaishi, Hideto Chono, Junichi Mineno, Takao Komatsuno, Yoshimi Saito, Hiromi Rakugi, Ryuichi Morishita, Hironori Nakagami

Current research in translational medicine　Vol. 70　No. 4　p. 103348-103348　2022/04/20　Research paper (scientific journal)

Establishment of monoclonal antibodies broadly neutralize infection of hepatitis B virus.

He Zhang, Yumi Itoh, Tatsuya Suzuki, Kan-Ichiro Ihara, Tomohisa Tanaka, Saori Haga, Hajime Enatsu, Maho Yumiya, Mari Kimura, Akira Takada, Daiki Itoh, Yuri Shibazaki, Shuto Nakao, Sachiyo Yoshio, Kei Miyakawa, Yuki Miyamoto, Hanae Sasaki, Tadahiro Kajita, Masaya Sugiyama, Masashi Mizokami, Taro Tachibana, Akihide Ryo, Kohji Moriishi, Eiji Miyoshi, Tatsuya Kanto, Toru Okamoto, Yoshiharu Matsuura

Microbiology and immunology　Vol. 66　No. 4　p. 179-192　2022/04/01　Research paper (scientific journal)

SARS-CoV-2 infection triggers paracrine senescence and leads to a sustained senescence-associated inflammatory response

Shunya Tsuji, Shohei Minami, Rina Hashimoto, Yusuke Konishi, Tatsuya Suzuki, Tamae Kondo, Miwa Sasai, Shiho Torii, Chikako Ono, Shintaro Shichinohe, Shintaro Sato, Masahiro Wakita, Shintaro Okumura, Sosuke Nakano, Tatsuyuki Matsudaira, Tomonori Matsumoto, Shimpei Kawamoto, Masahiro Yamamoto, Tokiko Watanabe, Yoshiharu Matsuura, Kazuo Takayama, Takeshi Kobayashi, Toru Okamoto, Eiji Hara

Nature Aging　Vol. 2　No. 2　p. 115-124　2022/02　Research paper (scientific journal)

Ultrasensitive detection of SARS-CoV-2 nucleocapsid protein using large gold nanoparticle-enhanced surface plasmon resonance.

Taka-Aki Yano, Taira Kajisa, Masayuki Ono, Yoshiya Miyasaka, Yuichi Hasegawa, Atsushi Saito, Kunihiro Otsuka, Ayuko Sakane, Takuya Sasaki, Koji Yasutomo, Rina Hamajima, Yuta Kanai, Takeshi Kobayashi, Yoshiharu Matsuura, Makoto Itonaga, Takeshi Yasui

Scientific reports　Vol. 12　No. 1　p. 1060-1060　2022/01/20　Research paper (scientific journal)

Glycan engineering of the SARS-CoV-2 receptor-binding domain elicits cross-neutralizing antibodies for SARS-related viruses.

Ryo Shinnakasu, Shuhei Sakakibara, Hiromi Yamamoto, Po-Hung Wang, Saya Moriyama, Nicolas Sax, Chikako Ono, Atsushi Yamanaka, Yu Adachi, Taishi Onodera, Takashi Sato, Masaharu Shinkai, Ryosuke Suzuki, Yoshiharu Matsuura, Noritaka Hashii, Yoshimasa Takahashi, Takeshi Inoue, Kazuo Yamashita, Tomohiro Kurosaki

The Journal of experimental medicine　Vol. 218　No. 12　2021/12/06　Research paper (scientific journal)

Correlation of the Commercial Anti-SARS-CoV-2 Receptor Binding Domain Antibody Test with the Chemiluminescent Reduction Neutralizing Test and Possible Detection of Antibodies to Emerging Variants

Yoshitomo Morinaga, Hideki Tani, Yasushi Terasaki, Satoshi Nomura, Hitoshi Kawasuji, Takahisa Shimada, Emiko Igarashi, Yumiko Saga, Yoshihiro Yoshida, Rei Yasukochi, Makito Kaneda, Yushi Murai, Akitoshi Ueno, Yuki Miyajima, Yasutaka Fukui, Kentaro Nagaoka, Chikako Ono, Yoshiharu Matsuura, Takashi Fujimura, Yoichi Ishida, Kazunori Oishi, Yoshihiro Yamamoto

Microbiology Spectrum　Vol. 9　No. 3　2021/12/01　Research paper (scientific journal)

Age-Dependent Reduction in Neutralization against Alpha and Beta Variants of BNT162b2 SARS-CoV-2 Vaccine-Induced Immunity

Hitoshi Kawasuji, Yoshitomo Morinaga, Hideki Tani, Yumiko Saga, Makito Kaneda, Yushi Murai, Akitoshi Ueno, Yuki Miyajima, Yasutaka Fukui, Kentaro Nagaoka, Chikako Ono, Yoshiharu Matsuura, Hideki Niimi, Yoshihiro Yamamoto

Microbiology Spectrum　Vol. 9　No. 3　2021/12/01　Research paper (scientific journal)

COVID-19 cynomolgus macaque model reflecting human COVID-19 pathological conditions.

Emiko Urano, Tomotaka Okamura, Chikako Ono, Shiori Ueno, Satoshi Nagata, Haruhiko Kamada, Mahoko Higuchi, Mugi Furukawa, Wataru Kamitani, Yoshiharu Matsuura, Yoshihiro Kawaoka, Yasuhiro Yasutomi

Proceedings of the National Academy of Sciences of the United States of America　Vol. 118　No. 43　2021/10/26　Research paper (scientific journal)

HERC5 E3 ligase mediates ISGylation of hepatitis B virus X protein to promote viral replication.

Rheza Gandi Bawono, Takayuki Abe, Mengting Qu, Daisuke Kuroki, Lin Deng, Chieko Matsui, Akihide Ryo, Tetsuro Suzuki, Yoshiharu Matsuura, Masaya Sugiyama, Masashi Mizokami, Kunitada Shimotohno, Ikuo Shoji

The Journal of general virology　Vol. 102　No. 10　2021/10/01　Research paper (scientific journal)

Spread of genetically similar noroviruses in Bangkok, Thailand, through symptomatic and asymptomatic individuals.

Patcharaporn Boonyos, Michittra Boonchan, Benjarat Phattanawiboon, Nutthawan Nonthabenjawan, Ratana Tacharoenmuang, Ratigorn Gunpapong, Phakapun Singchai, Sompong Upchai, Pimpha Rungnobhakhun, Jutarat Mekmullica, Worakarn Towayunanta, Kobkool Chuntrakool, Karn Ngaopravet, Kriangsak Ruchusatsawat, Somchai Sangkitporn, Ballang Uppapong, Eisuke Mekada, Yoshiharu Matsuura, Masashi Tatsumi, Hiroto Mizushima

Heliyon　Vol. 7　No. 10　2021/10/01　Research paper (scientific journal)

A SARS-CoV-2 antibody broadly neutralizes SARS-related coronaviruses and variants by coordinated recognition of a virus-vulnerable site

Taishi Onodera, Shunsuke Kita, Yu Adachi, Saya Moriyama, Akihiko Sato, Takao Nomura, Shuhei Sakakibara, Takeshi Inoue, Takashi Tadokoro, Yuki Anraku, Kohei Yumoto, Cong Tian, Hideo Fukuhara, Michihito Sasaki, Yasuko Orba, Nozomi Shiwa, Naoko Iwata, Noriyo Nagata, Tateki Suzuki, Jiei Sasaki, Tsuyoshi Sekizuka, Keisuke Tonouchi, Lin Sun, Shuetsu Fukushi, Hiroyuki Satofuka, Yasuhiro Kazuki, Mitsuo Oshimura, Tomohiro Kurosaki, Makoto Kuroda, Yoshiharu Matsuura, Tadaki Suzuki, Hirofumi Sawa, Takao Hashiguchi, Katsumi Maenaka, Yoshimasa Takahashi

Immunity　Vol. 54　No. 10　p. 2385-2398　2021/10/01　Research paper (scientific journal)

Virucidal effect of acetic acid and vinegar on severe acute respiratory syndrome coronavirus 2

Joto Yoshimoto, Chikako Ono, Yoshihiro Tsuchiya, Shizuya Kabuto, Mikiya Kishi, Yoshiharu Matsuura

Food Science and Technology Research　Vol. 27　No. 4　p. 681-684　2021/08/05　Research paper (scientific journal)

SARS-CoV-2 spike L452R variant evades cellular immunity and increases infectivity

Chihiro Motozono, Mako Toyoda, Jiri Zahradnik, Akatsuki Saito, Hesham Nasser, Toong Seng Tan, Isaac Ngare, Izumi Kimura, Keiya Uriu, Yusuke Kosugi, Yuan Yue, Ryo Shimizu, Jumpei Ito, Shiho Torii, Akiko Yonekawa, Nobuyuki Shimono, Yoji Nagasaki, Rumi Minami, Takashi Toya, Noritaka Sekiya, Takasuke Fukuhara, Yoshiharu Matsuura, Gideon Schreiber, Terumasa Ikeda, So Nakagawa, Takamasa Ueno, Kei Sato

Cell Host and Microbe　Vol. 29　No. 7　p. 1124-1.14E+14　2021/07/14　Research paper (scientific journal)

DsRNA sequencing for RNA virus surveillance using human clinical samples

Takuma Izumi, Yuhei Morioka, Syun Ichi Urayama, Daisuke Motooka, Tomokazu Tamura, Takahiro Kawagishi, Yuta Kanai, Takeshi Kobayashi, Chikako Ono, Akinari Morinaga, Takahiro Tomiyama, Norifumi Iseda, Yukiko Kosai, Shoichi Inokuchi, Shota Nakamura, Tomohisa Tanaka, Kohji Moriishi, Hiroaki Kariwa, Tomoharu Yoshizumi, Masaki Mori, Yoshiharu Matsuura, Takasuke Fukuhara

Viruses　Vol. 13　No. 7　2021/07/01　Research paper (scientific journal)

An infectivity-enhancing site on the SARS-CoV-2 spike protein targeted by antibodies

Yafei Liu, Wai Tuck Soh, Jun ichi Kishikawa, Mika Hirose, Emi E. Nakayama, Songling Li, Miwa Sasai, Tatsuya Suzuki, Asa Tada, Akemi Arakawa, Sumiko Matsuoka, Kanako Akamatsu, Makoto Matsuda, Chikako Ono, Shiho Torii, Kazuki Kishida, Hui Jin, Wataru Nakai, Noriko Arase, Atsushi Nakagawa, Maki Matsumoto, Yukoh Nakazaki, Yasuhiro Shindo, Masako Kohyama, Keisuke Tomii, Koichiro Ohmura, Shiro Ohshima, Toru Okamoto, Masahiro Yamamoto, Hironori Nakagami, Yoshiharu Matsuura, Takayuki Kato, Masato Okada, Daron M. Standley, Tatsuo Shioda, Hisashi Arase

Cell　Vol. 184　No. 13　p. 3452-3.47E+21　2021/06/24　Research paper (scientific journal)

Hepatitis C virus modulates signal peptide peptidase to alter host protein processing

Junki Hirano, Sachiyo Yoshio, Yusuke Sakai, Li Songling, Tatsuya Suzuki, Yumi Itoh, He Zhang, David Virya Chen, Saori Haga, Hiroko Oomori, Takahiro Kodama, Yusuke Maeda, Yoshihiro Ono, Yu Takahashi, Daron M. Standley, Masahiro Yamamoto, Kohji Moriishi, Kyoji Moriya, Tatsuya Kanto, Tetsuo Takehara, Kazuhiko Koike, Yoshiharu Matsuura, Toru Okamoto

Proceedings of the National Academy of Sciences of the United States of America　Vol. 118　No. 22　2021/06/01　Research paper (scientific journal)

M segment-based minigenome system of severe fever with thrombocytopenia syndrome virus as a tool for antiviral drug screening

Hiroshi Yamada, Satoshi Taniguchi, Masayuki Shimojima, Long Tan, Miyuki Kimura, Yoshitomo Morinaga, Takasuke Fukuhara, Yoshiharu Matsuura, Takashi Komeno, Yousuke Furuta, Masayuki Saijo, Hideki Tani

Viruses　Vol. 13　No. 6　2021/06/01　Research paper (scientific journal)

Combining machine learning and nanopore construction creates an artificial intelligence nanopore for coronavirus detection

Masateru Taniguchi, Shohei Minami, Chikako Ono, Rina Hamajima, Ayumi Morimura, Shigeto Hamaguchi, Yukihiro Akeda, Yuta Kanai, Takeshi Kobayashi, Wataru Kamitani, Yutaka Terada, Koichiro Suzuki, Nobuaki Hatori, Yoshiaki Yamagishi, Nobuei Washizu, Hiroyasu Takei, Osamu Sakamoto, Norihiko Naono, Kenji Tatematsu, Takashi Washio, Yoshiharu Matsuura, Kazunori Tomono

Nature Communications　Vol. 12　No. 1　2021/06/01　Research paper (scientific journal)

Engineered ACE2 receptor therapy overcomes mutational escape of SARS-CoV-2

Yusuke Higuchi, Tatsuya Suzuki, Takao Arimori, Nariko Ikemura, Emiko Mihara, Yuhei Kirita, Eriko Ohgitani, Osam Mazda, Daisuke Motooka, Shota Nakamura, Yusuke Sakai, Yumi Itoh, Fuminori Sugihara, Yoshiharu Matsuura, Satoaki Matoba, Toru Okamoto, Junichi Takagi, Atsushi Hoshino

Nature Communications　Vol. 12　No. 1　2021/06/01　Research paper (scientific journal)

Establishment of a Cell Culture Model Permissive for Infection by Hepatitis B and C Viruses

Teruhime Otoguro, Tomohisa Tanaka, Hirotake Kasai, Nobuhiro Kobayashi, Atsuya Yamashita, Takasuke Fukuhara, Akihide Ryo, Moto Fukai, Akinobu Taketomi, Yoshiharu Matsuura, Kohji Moriishi

Hepatology Communications　Vol. 5　No. 4　p. 634-649　2021/04/01　Research paper (scientific journal)

Establishment of a reverse genetics system for SARS-CoV-2 using circular polymerase extension reaction

Shiho Torii, Chikako Ono, Rigel Suzuki, Yuhei Morioka, Itsuki Anzai, Yuzy Fauzyah, Yusuke Maeda, Wataru Kamitani, Takasuke Fukuhara, Yoshiharu Matsuura

Cell Reports　Vol. 35　No. 3　2021/04/01　Research paper (scientific journal)

Deneddylation by SENP8 restricts hepatitis B virus propagation

David Virya Chen, Tatsuya Suzuki, Yumi Itoh, Yusuke Maeda, Junki Hirano, Saori Haga, He Zhang, Daiki Ito, Yoshiharu Matsuura, Toru Okamoto

Microbiology and Immunology　Vol. 65　No. 3　p. 125-135　2021/03/01　Research paper (scientific journal)

Induction of HOX genes by hepatitis C virus infection via impairment of histone H2A monoubiquitination

Hirotake Kasai, Kazuki Mochizuki, Tomohisa Tanaka, Atsuya Yamashita, Yoshiharu Matsuura, Kohji Moriishi

Journal of Virology　Vol. 95　No. 6　2021/03/01　Research paper (scientific journal)

Suppression of optineurin impairs the progression of hepatocellular carcinoma through regulating mitophagy

Shoichi Inokuchi, Tomoharu Yoshizumi, Takeo Toshima, Shinji Itoh, Kyohei Yugawa, Noboru Harada, Hiroyuki Mori, Takasuke Fukuhara, Yoshiharu Matsuura, Masaki Mori

Cancer Medicine　Vol. 10　No. 5　p. 1501-1514　2021/03/01　Research paper (scientific journal)

SARS-CoV-2-induced humoral immunity through B cell epitope analysis in COVID-19 infected individuals

Shota Yoshida, Chikako Ono, Hiroki Hayashi, Shinya Fukumoto, Satoshi Shiraishi, Kazunori Tomono, Hisashi Arase, Yoshiharu Matsuura, Hironori Nakagami

Scientific Reports　Vol. 11　No. 1　2021/03/01　Research paper (scientific journal)

Ponesimod suppresses hepatitis B virus infection by inhibiting endosome maturation

Yuzy Fauzyah, Chikako Ono, Shiho Torii, Itsuki Anzai, Rigel Suzuki, Takuma Izumi, Yuhei Morioka, Yusuke Maeda, Toru Okamoto, Takasuke Fukuhara, Yoshiharu Matsuura

Antiviral Research　Vol. 186　2021/02/01　Research paper (scientific journal)

Identification of GII.14[P7] norovirus and its genomic mutations from a case of long-term infection in a post-symptomatic individual

Nutthawan Nonthabenjawan, Patcharaporn Boonyos, Benjarat Phattanawiboon, Worakarn Towayunanta, Kobkool Chuntrakool, Karn Ngaopravet, Kriangsak Ruchusatsawat, Ballang Uppapong, Somchai Sangkitporn, Eisuke Mekada, Yoshiharu Matsuura, Masashi Tatsumi, Hiroto Mizushima

Infection, Genetics and Evolution　Vol. 86　2020/12/01　Research paper (scientific journal)

Generation of Genetically RGD σ1-Modified Oncolytic Reovirus That Enhances JAM-A-Independent Infection of Tumor Cells

Takahiro Kawagishi, Yuta Kanai, Ryotaro Nouda, Ichika Fukui, Jeffery A. Nurdin, Yoshiharu Matsuura, Takeshi Kobayashi

Journal of Virology　Vol. 94　No. 23　2020/12/01　Research paper (scientific journal)

Anti-chikungunya virus monoclonal antibody that inhibits viral fusion and release

Uranan Tumkosit, Uamporn Siripanyaphinyo, Naokazu Takeda, Motonori Tsuji, Yusuke Maeda, Kriangsak Ruchusatsawat, Tatsuo Shioda, Hiroto Mizushima, Prukswan Chetanachan, Pattara Wongjaroen, Yoshiharu Matsuura, Masashi Tatsumi, Atsushi Tanaka

Journal of Virology　Vol. 94　No. 19　2020/10/01　Research paper (scientific journal)

Isgylation of Hepatitis C virus ns5a protein promotes viral rna replication via recruitment of cyclophilin a

Takayuki Abe, Nanae Minami, Rheza Gandi Bawono, Chieko Matsui, Lin Deng, Takasuke Fukuhara, Yoshiharu Matsuura, Ikuo Shoji

Journal of Virology　Vol. 94　No. 20　2020/09/29　Research paper (scientific journal)

IL-6 trans-signaling induces plasminogen activator inhibitor-1 from vascular endothelial cells in cytokine release syndrome

Sujin Kang, Toshio Tanaka, Hitomi Inoue, Chikako Ono, Shoji Hashimoto, Yoshiyuki Kioi, Hisatake Matsumoto, Hiroshi Matsuura, Tsunehiro Matsubara, Kentaro Shimizu, Hiroshi Ogura, Yoshiharu Matsuura, Tadamitsu Kishimoto

Proceedings of the National Academy of Sciences of the United States of America　Vol. 117　No. 36　p. 22351-22356　2020/09/08　Research paper (scientific journal)

Norovirus transmission mediated by asymptomatic family members in households

Benjarat Phattanawiboon, Nutthawan Nonthabenjawan, Patcharaporn Boonyos, Chanya Jetsukontorn, Worakarn Towayunanta, Kobkool Chuntrakool, Karn Ngaopravet, Kriangsak Ruchusatsawat, Ballang Uppapong, Somchai Sangkitporn, Eisuke Mekada, Yoshiharu Matsuura, Masashi Tatsumi, Hiroto Mizushima

PLoS ONE　Vol. 15　No. 7-Jul　2020/07/01　Research paper (scientific journal)

Various miRNAs compensate the role of miR-122 on HCV replication

Chikako Ono, Takasuke Fukuhara, Songling Li, Jian Wang, Asuka Sato, Takuma Izumi, Yuzy Fauzyah, Takuya Yamamoto, Yuhei Morioka, Nikolay V. Dokholyan, Daron M. Standley, Yoshiharu Matsuura

PLoS Pathogens　Vol. 16　No. 6 June　2020/06　Research paper (scientific journal)

Host ESCRT factors are recruited during Chikungunya virus infection and are required during the intracellular viral replication cycle

Shiho Torii, Yasuko Orba, Michihito Sasaki, Koshiro Tabata, Yuji Wada, Michael Carr, Jody Hobson-Peters, Roy A. Hall, Ayato Takada, Takasuke Fukuhara, Yoshiharu Matsuura, William W. Hall, Hirofumi Sawa

Journal of Biological Chemistry　Vol. 295　No. 23　p. 7941-7957　2020/04　Research paper (scientific journal)

Dysregulated Expression of the Nuclear Exosome Targeting Complex Component Rbm7 in Nonhematopoietic Cells Licenses the Development of Fibrosis

Kiyoharu Fukushima, Takashi Satoh, Fuminori Sugihara, Yuki Sato, Toru Okamoto, Yuichi Mitsui, Sachiyo Yoshio, Songling Li, Satoshi Nojima, Daisuke Motooka, Shota Nakamura, Hiroshi Kida, Daron M. Standley, Eiichi Morii, Tatsuya Kanto, Motoko Yanagita, Yoshiharu Matsuura, Takashi Nagasawa, Atsushi Kumanogoh, Shizuo Akira

Immunity　Vol. 52　No. 3　p. 542-556.e13　2020/03/17　Research paper (scientific journal)

Development of a high-throughput serum neutralization test using recombinant pestiviruses possessing a small reporter tag

Madoka Tetsuo, Keita Matsuno, Tomokazu Tamura, Takasuke Fukuhara, Taksoo Kim, Masatoshi Okamatsu, Norbert Tautz, Yoshiharu Matsuura, Yoshihiro Sakoda

Pathogens　Vol. 9　No. 3　2020/03　Research paper (scientific journal)

Novel anti-flavivirus drugs targeting the nucleolar distribution of core protein

Makoto Tokunaga, Yoichi Miyamoto, Tatsuya Suzuki, Mayumi Otani, Shinsuke Inuki, Tsuyoshi Esaki, Chioko Nagao, Kenji Mizuguchi, Hiroaki Ohno, Yoshihiro Yoneda, Toru Okamoto, Masahiro Oka, Yoshiharu Matsuura

Virology　Vol. 541　p. 41-51　2020/02　Research paper (scientific journal)

Neo-virology: The raison d'etre of viruses

Tokiko Watanabe, Nobuhiro Suzuki, Keizo Tomonaga, Hirofumi Sawa, Yoshiharu Matsuura, Yasushi Kawaguchi, Hideki Takahashi, Keizo Nagasaki, Yoshihiro Kawaoka

Virus Research　Vol. 274　p. 197751-197751　2019/12　Research paper (scientific journal)

Characterization of human pegivirus infection in liver transplantation recipients

Takuma Izumi, Kazuhito Sakata, Daisuke Okuzaki, Shoichi Inokuchi, Tomokazu Tamura, Daisuke Motooka, Shota Nakamura, Chikako Ono, Masahiro Shimokawa, Yoshiharu Matsuura, Masaki Mori, Takasuke Fukuhara, Tomoharu Yoshizumi

Journal of Medical Virology　Vol. 91　No. 12　p. 2093-2100　2019/12/01　Research paper (scientific journal)

In vivo dynamics of reporter flaviviridae viruses

Tomokazu Tamura, Manabu Igarashi, Bazarragchaa Enkhbold, Tatsuya Suzuki, Masatoshi Okamatsu, Chikako Ono, Hiroyuki Mori, Takuma Izumi, Asuka Sato, Yuzy Fauzyah, Toru Okamoto, Yoshihiro Sakoda, Takasuke Fukuhara, Yoshiharu Matsuura

Journal of Virology　Vol. 93　No. 22　2019/11/01　Research paper (scientific journal)

Bone morphogenetic protein 4 provides cancer-supportive phenotypes to liver fibroblasts in patients with hepatocellular carcinoma

Yohei Mano, Sachiyo Yoshio, Hirotaka Shoji, Shimagaki Tomonari, Yoshihiko Aoki, Nobuyoshi Aoyanagi, Toru Okamoto, Yoshiharu Matsuura, Yosuke Osawa, Kiminori Kimura, Kyohei Yugawa, Huanlin Wang, Yoshinao Oda, Tomoharu Yoshizumi, Yoshihiko Maehara, Tatsuya Kanto

Journal of Gastroenterology　Vol. 54　No. 11　p. 1007-1018　2019/11/01　Research paper (scientific journal)

Roles of secretory glycoproteins in particle formation of Flaviviridae viruses

Takasuke Fukuhara, Yoshiharu Matsuura

Microbiology and Immunology　Vol. 63　No. 10　p. 401-406　2019/10/01

CXCR4 regulates Plasmodium development in mouse and human hepatocytes

Hironori Bando, Ariel Pradipta, Shiroh Iwanaga, Toru Okamoto, Daisuke Okuzaki, Shun Tanaka, Joel Vega-Rodríguez, Youngae Lee, Ji Su Ma, Naoya Sakaguchi, Akira Soga, Shinya Fukumoto, Miwa Sasai, Yoshiharu Matsuura, Masao Yuda, Marcelo Jacobs-Lorena, Masahiro Yamamoto

Journal of Experimental Medicine　Vol. 216　No. 8　p. 1733-1748　2019/08/01　Research paper (scientific journal)

In vivo live imaging of oncolytic mammalian orthoreovirus expressing nanoluc luciferase in tumor xenograft mice

Yuta Kanai, Takahiro Kawagishi, Yoshiharu Matsuura, Takeshi Kobayashi

Journal of Virology　Vol. 93　No. 14　2019/07　Research paper (scientific journal)

Cell-cell fusion induced by reovirus FAST proteins enhances replication and pathogenicity of non-enveloped dsRNA viruses

Yuta Kanai, Takahiro Kawagishi, Yusuke Sakai, Ryotaro Nouda, Masayuki Shimojima, Masayuki Saijo, Yoshiharu Matsuura, Takeshi Kobayashi

PLoS Pathogens　Vol. 15　No. 4　2019/04　Research paper (scientific journal)

Peroxiredoxin 1, a novel HBX-interacting protein, interacts with exosome component 5 and negatively regulates hepatitis B virus (HBV) propagation through degradation of HBV RNA

Lin Deng, Xiang Gan, Masahiko Ito, Ming Chen, Hussein H. Aly, Chieko Matsui, Takayuki Abe, Koichi Watashi, Takaji Wakita, Tetsuro Suzuki, Toru Okamoto, Yoshiharu Matsuura, Masashi Mizokami, Ikuo Shoji, Hak Hotta

Journal of Virology　Vol. 93　No. 6　2019/03/01　Research paper (scientific journal)

USP15 participates in hepatitis C virus propagation through regulation of viral RNA translation and lipid droplet formation

Shinji Kusakabe, Tatsuya Suzuki, Yukari Sugiyama, Saori Haga, Kanako Horike, Makoto Tokunaga, Junki Hirano, He Zhang, David Virya Chen, Hanako Ishiga, Yasumasa Komoda, Chikako Ono, Takasuke Fukuhara, Masahiro Yamamoto, Masahito Ikawa, Takashi Satoh, Shizuo Akira, Tomohisa Tanaka, Kohji Moriishi, Moto Fukai, Akinobu Taketomi, Sachiyo Yoshio, Tatsuya Kanto, Tetsuro Suzuki, Toru Okamoto, Yoshiharu Matsuura

Journal of Virology　Vol. 93　No. 6　2019/03/01　Research paper (scientific journal)

N-terminal HCV core protein fragment decreases 20S proteasome activity in the presence of PA28γ

Yang Zheng, Shigeru Shimamoto, Takahiro Maruno, Yuji Kobayashi, Yoshiharu Matsuura, Kazuki Kawahara, Takuya Yoshida, Tadayasu Ohkubo

Biochemical and Biophysical Research Communications　Vol. 509　No. 2　p. 590-595　2019/02/05　Research paper (scientific journal)

Development of stable rotavirus reporter expression systems

Yuta Kanai, Takahiro Kawagishi, Ryotaro Nouda, Misa Onishi, Pimfhun Pannacha, Jeffery A. Nurdin, Keiichiro Nomura, Yoshiharu Matsuura, Takeshi Kobayashi

Journal of Virology　Vol. 93　No. 4　2019/02/01　Research paper (scientific journal)

N-terminal HCV core protein fragment decreases 20S proteasome activity in the presence of PA28γ

Zheng Y, Shimamoto S, Maruno T, Kobayashi Y, Matsuura Y, Kawahara K, Yoshida T, Ohkubo T

Biochem Biophys Res Commun.　Vol. 509　No. 2　p. 590-595　2019/02　Research paper (scientific journal)

Oenothein B, dimeric hydrolysable tannin inhibiting HCV invasion from Oenothera erythrosepala

Satoru Tamura, Gang Ming Yang, Teruaki Koitabashi, Yoshiharu Matsuura, Yasumasa Komoda, Tomikazu Kawano, Nobutoshi Murakami

Journal of Natural Medicines　Vol. 73　No. 1　p. 67-75　2019/01/25　Research paper (scientific journal)

Establishment of a virulent full-length cDNA clone for type I feline coronavirus strain C3663

Yutaka Terada, Yudai Kuroda, Shigeru Morikawa, Yoshiharu Matsuura, Ken Maeda, Wataru Kamitani

Journal of Virology　Vol. 93　No. 21　2019　Research paper (scientific journal)

USP15 participates in HCV propagation through the regulation of viral RNA translation and lipid droplet formation.

Kusakabe S, Suzuki T, Sugiyama Y, Haga S, Horike K, Tokunaga M, Hirano J, He Z, Chen DV, Ishiga H, Komoda Y, Ono C, Fukuhara T, Yamamoto M, Ikawa M, Satoh T, Akira S, Tanaka T, Moriishi K, Fukai M, Taketomi A, Yoshio S, Kanto T, Suzuki T, Okamoto T, Matsuura Y

J Virol.　2019/01　Research paper (scientific journal)

Induction of selective autophagy in cells replicating hepatitis C virus genome

Hiroyuki Mori, Takasuke Fukuhara, Chikako Ono, Tomokazu Tamura, Asuka Sato, Yuzy Fauzyah, Masami Wada, Toru Okamoto, Takeshi Noda, Tamotsu Yoshimori, Yoshiharu Matsuura

Journal of General Virology　Vol. 99　No. 12　p. 1643-1657　2018/12　Research paper (scientific journal)

CEACAM1 Is Associated With the Suppression of Natural Killer Cell Function in Patients With Chronic Hepatitis C.

Takahiro Suda, Tomohide Tatsumi, Akira Nishio, Tadashi Kegasawa, Teppei Yoshioka, Ryoko Yamada, Kunimaro Furuta, Takahiro Kodama, Minoru Shigekawa, Hayato Hikita, Ryotaro Sakamori, Takasuke Fukuhara, Yoshiharu Matsuura, Tetsuo Takehara

Hepatology communications　Vol. 2　No. 10　p. 1247-1258　2018/10　Research paper (scientific journal)

Baculovirus as a tool for gene delivery and gene therapy

Chikako Ono, Toru Okamoto, Takayuki Abe, Yoshiharu Matsuura

Viruses　Vol. 10　No. 9　2018/09/19

St6gal1 knockdown alters HBV life cycle in HepAD38 cells

Surya Agung Priyambada, Ryo Misaki, Toru Okamoto, Takao Ohashi, Keiji Ueda, Yoshiharu Matsuura, Kazuhito Fujiyama

Biochemical and Biophysical Research Communications　Vol. 503　No. 3　p. 1841-1847　2018/09/10　Research paper (scientific journal)

Infection with flaviviruses requires BCLX<inf>L</inf> for cell survival

Tatsuya Suzuki, Toru Okamoto, Hiroshi Katoh, Yukari Sugiyama, Shinji Kusakabe, Makoto Tokunaga, Junki Hirano, Yuka Miyata, Takasuke Fukuhara, Masahito Ikawa, Takashi Satoh, Sachiyo Yoshio, Ryosuke Suzuki, Masayuki Saijo, David C.S. Huang, Tatsuya Kanto, Shizuo Akira, Yoshiharu Matsuura

PLoS Pathogens　Vol. 14　No. 9　2018/09　Research paper (scientific journal)

Novel miRNA biomarkers for genotoxicity screening in mouse

Hiroyuki Oka, Koichi Masuno, Takeki Uehara, Toru Okamoto, Yoshiharu Matsuura, Toru Nakano, Shinpei Yamaguchi

Toxicology　Vol. 404-405　p. 68-75　2018/07/01　Research paper (scientific journal)

Discovery of peroxisome proliferator-activated receptor α (PPARα) activators with a ligand-screening system using a human PPARα-expressing cell line

Keisuke Tachibana, Tomohiro Yuzuriha, Ryotaro Tabata, Syohei Fukuda, Takashi Maegawa, Rika Takahashi, Keiichi Tanimoto, Hirofumi Tsujino, Kazuto Nunomura, Bangzhong Lin, Yoshiharu Matsuura, Toshiya Tanaka, Takao Hamakubo, Juro Sakai, Tatsuhiko Kodama, Tadayuki Kobayashi, Kenji Ishimoto, Hiroyuki Miyachi, Takefumi Doi

Journal of Biological Chemistry　Vol. 293　No. 26　p. 10333-10343　2018/06/29　Research paper (scientific journal)

Roles of the 5' untranslated region of nonprimate hepacivirus in translation initiation and viral replication

Tomohisa Tanaka, Teruhime Otoguro, Atsuya Yamashita, Hirotake Kasai, Takasuke Fukuhara, Yoshiharu Matsuura, Kohji Moriishi

Journal of Virology　Vol. 92　No. 7　2018/04　Research paper (scientific journal)

A novel occludin-targeting monoclonal antibody prevents hepatitis C virus infection in vitro

Ken Okai, Naoki Ichikawa-Tomikawa, Akira C. Saito, Tetsuya Watabe, Kotaro Sugimoto, Daiki Fujita, Chikako Ono, Takasuke Fukuhara, Yoshiharu Matsuura, Hiromasa Ohira, Hideki Chiba

Oncotarget　Vol. 9　No. 24　p. 16588-16598　2018/03/30　Research paper (scientific journal)

Evaluation of viral contamination in a baculovirus expression system

Chikako Ono, Junki Hirano, Toru Okamoto, Yoshiharu Matsuura

Microbiology and Immunology　Vol. 62　No. 3　p. 200-204　2018/03　Research paper (scientific journal)

Lethal murine infection model for human respiratory disease-associated Pteropine orthoreovirus

Yuta Kanai, Takahiro Kawagishi, Minoru Okamoto, Yusuke Sakai, Yoshiharu Matsuura, Takeshi Kobayashi

Virology　Vol. 514　p. 57-65　2018/01/15　Research paper (scientific journal)

Characterization of recombinant Flaviviridae viruses possessing a small reporter Tag

Tomokazu Tamura, Takasuke Fukuhara, Takuro Uchida, Chikako Ono, Hiroyuki Mori, Asuka Sato, Yuzy Fauzyah, Toru Okamoto, Takeshi Kurosu, Yin Xiang Setoh, Michio Imamura, Norbert Tautz, Yoshihiro Sakoda, Alexander A. Khromykh, Kazuaki Chayama, Yoshiharu Matsuura

Journal of Virology　Vol. 92　No. 2　2018/01/01　Research paper (scientific journal)

Characterization of SPP inhibitors suppressing propagation of HCV and protozoa

Junki Hirano, Toru Okamoto, Yukari Sugiyama, Tatsuya Suzuki, Shinji Kusakabe, Makoto Tokunaga, Takasuke Fukuhara, Miwa Sasai, Takahiro Tougan, Yasue Matsunaga, Kazuo Yamashita, Yusuke Sakai, Masahiro Yamamoto, Toshihiro Horii, Daron M. Standley, Kohji Moriishi, Kyoji Moriya, Kazuhiko Koike, Yoshiharu Matsuura

Proceedings of the National Academy of Sciences of the United States of America　Vol. 114　No. 50　p. E10782-E10791　2017/12/12　Research paper (scientific journal)

Suppression of HBV replication by the expression of nickase-and nuclease dead-Cas9

Takeshi Kurihara, Takasuke Fukuhara, Chikako Ono, Satomi Yamamoto, Kentaro Uemura, Toru Okamoto, Masaya Sugiyama, Daisuke Motooka, Shota Nakamura, Masato Ikawa, Masashi Mizokami, Yoshihiko Maehara, Yoshiharu Matsuura

Scientific Reports　Vol. 7　No. 1　2017/12/01　Research paper (scientific journal)

MERS coronavirus nsp1 participates in an efficient propagation through a specific interaction with viral RNA

Yutaka Terada, Kengo Kawachi, Yoshiharu Matsuura, Wataru Kamitani

Virology　Vol. 511　p. 95-105　2017/11　Research paper (scientific journal)

Reverse genetics system demonstrates that rotavirus nonstructural protein NSP6 is not essential for viral replication in cell cultures

Satoshi Komoto, Yuta Kanai, Saori Fukuda, Masanori Kugita, Takahiro Kawagishi, Naoto Ito, Makoto Sugiyama, Yoshiharu Matsuura, Takeshi Kobayashi, Koki Taniguchi

Journal of Virology　Vol. 91　No. 21　2017/11/01　Research paper (scientific journal)

Semagacestat Is a Pseudo-Inhibitor of γ-Secretase

Shinji Tagami, Kanta Yanagida, Takashi S. Kodama, Mako Takami, Naoki Mizuta, Hiroshi Oyama, Kouhei Nishitomi, Yu wen Chiu, Toru Okamoto, Takeshi Ikeuchi, Gaku Sakaguchi, Takashi Kudo, Yoshiharu Matsuura, Akio Fukumori, Masatoshi Takeda, Yasuo Ihara, Masayasu Okochi

Cell Reports　Vol. 21　No. 1　p. 259-273　2017/10/03　Research paper (scientific journal)

Two-amino acids change in the nsp4 of SARS coronavirus abolishes viral replication

Yusuke Sakai, Kengo Kawachi, Yutaka Terada, Hiroko Omori, Yoshiharu Matsuura, Wataru Kamitani

Virology　Vol. 510　p. 165-174　2017/10　Research paper (scientific journal)

The RAB2B-GARIL5 Complex Promotes Cytosolic DNA-Induced Innate Immune Responses

Michihiro Takahama, Mitsunori Fukuda, Norihiko Ohbayashi, Tatsuya Kozaki, Takuma Misawa, Toru Okamoto, Yoshiharu Matsuura, Shizuo Akira, Tatsuya Saitoh

Cell Reports　Vol. 20　No. 12　p. 2944-2954　2017/09/19　Research paper (scientific journal)

Unconjugated interferon-stimulated gene 15 specifically interacts with the hepatitis C virus NS5A protein via domain I

Nanae Minami, Takayuki Abe, Lin Deng, Chieko Matsui, Takasuke Fukuhara, Yoshiharu Matsuura, Ikuo Shoji

Microbiology and Immunology　Vol. 61　No. 7　p. 287-292　2017/07　Research paper (scientific journal)

Cell surface N-glycan alteration in HepAD38 cell lines expressing Hepatitis B virus

Surya Agung Priyambada, Ryo Misaki, Toru Okamoto, Yuta Okamoto, Takao Ohashi, Keiji Ueda, Yoshiharu Matsuura, Kazuhito Fujiyama

Virus Research　Vol. 238　p. 101-109　2017/06/15　Research paper (scientific journal)

Characterization of miR-122-independent propagation of HCV

Chikako Ono, Takasuke Fukuhara, Daisuke Motooka, Shota Nakamura, Daisuke Okuzaki, Satomi Yamamoto, Tomokazu Tamura, Hiroyuki Mori, Asuka Sato, Kentaro Uemura, Yuzy Fauzyah, Takeshi Kurihara, Takahiro Suda, Akira Nishio, Su Su Hmwe, Toru Okamoto, Tomohide Tatsumi, Tetsuo Takehara, Kazuaki Chayama, Takaji Wakita, Kazuhiko Koike, Yoshiharu Matsuura

PLoS Pathogens　Vol. 13　No. 5　2017/05　Research paper (scientific journal)

Quasispecies of Hepatitis C Virus Participate in Cell-Specific Infectivity

Takasuke Fukuhara, Satomi Yamamoto, Chikako Ono, Shota Nakamura, Daisuke Motooka, Hiroyuki Mori, Takeshi Kurihara, Asuka Sato, Tomokazu Tamura, Takashi Motomura, Toru Okamoto, Michio Imamura, Toru Ikegami, Tomoharu Yoshizumi, Yuji Soejima, Yoshihiko Maehara, Kazuaki Chayama, Yoshiharu Matsuura

Scientific Reports　Vol. 7　2017/03/22　Research paper (scientific journal)

Mitochondrial damage elicits a TCDD-inducible poly(ADP-ribose) polymerase-mediated antiviral response

Tatsuya Kozaki, Jun Komano, Daiki Kanbayashi, Michihiro Takahama, Takuma Misawa, Takashi Satoh, Osamu Takeuchi, Taro Kawai, Shigeomi Shimizu, Yoshiharu Matsuura, Shizuo Akira, Tatsuya Saitoh

Proceedings of the National Academy of Sciences of the United States of America　Vol. 114　No. 10　p. 2681-2686　2017/03/07　Research paper (scientific journal)

Entirely plasmid-based reverse genetics system for rotaviruses

Yuta Kanai, Satoshi Komoto, Takahiro Kawagishi, Ryotaro Nouda, Naoko Nagasawa, Misa Onishi, Yoshiharu Matsuura, Koki Taniguchi, Takeshi Kobayashi

Proceedings of the National Academy of Sciences of the United States of America　Vol. 114　No. 9　p. 2343-2348　2017/02/28　Research paper (scientific journal)

Development of hepatoma-derived, bidirectional oval-like cells as a model to study host interactions with hepatitis C virus during differentiation

Masahiko Ito, Suofeng Sun, Takasuke Fukuhara, Ryosuke Suzuki, Miho Tamai, Toyohiko Yamauchi, Kenji Nakashima, Yoh ichi Tagawa, Shigetoshi Okazaki, Yoshiharu Matsuura, Takaji Wakita, Tetsuro Suzuki

Oncotarget　Vol. 8　No. 33　p. 53899-53915　2017　Research paper (scientific journal)

Host-derived apolipoproteins play comparable roles with viral secretory proteins E^rnsand NS1 in the infectious particle formation of Flaviviridae

Takasuke Fukuhara, Tomokazu Tamura, Chikako Ono, Mai Shiokawa, Hiroyuki Mori, Kentaro Uemura, Satomi Yamamoto, Takeshi Kurihara, Toru Okamoto, Ryosuke Suzuki, Kentaro Yoshii, Takeshi Kurosu, Manabu Igarashi, Hiroshi Aoki, Yoshihiro Sakoda, Yoshiharu Matsuura

PLoS Pathogens　Vol. 13　No. 6　2017　Research paper (scientific journal)

Nonstructural 5A protein of hepatitis C virus interferes with toll-like receptor signaling and suppresses the interferon response in mouse liver

Takeya Tsutsumi, Kazuya Okushin, Kenichiro Enooku, Hidetaka Fujinaga, Kyoji Moriya, Hiroshi Yotsuyanagi, Hideki Aizaki, Tetsuro Suzuki, Yoshiharu Matsuura, Kazuhiko Koike

PLoS ONE　Vol. 12　No. 1　2017/01　Research paper (scientific journal)

Extensive Ca²⁺ leak through K4750Q cardiac ryanodine receptors caused by cytosolic and luminal Ca²⁺ hypersensitivity

Akira Uehara, Takashi Murayama, Midori Yasukochi, Michael Fill, Minoru Horie, Toru Okamoto, Yoshiharu Matsuura, Kiyoko Uehara, Takahiro Fujimoto, Takashi Sakurai, Nagomi Kurebayashi

Journal of General Physiology　Vol. 149　No. 2　p. 199-218　2017　Research paper (scientific journal)

CD14⁺ monocyte-derived galectin-9 induces natural killer cell cytotoxicity in chronic hepatitis C

Akira Nishio, Tomohide Tatsumi, Takatoshi Nawa, Takahiro Suda, Teppei Yoshioka, Yoshiki Onishi, Satoshi Aono, Minoru Shigekawa, Hayato Hikita, Ryotaro Sakamori, Daisuke Okuzaki, Takasuke Fukuhara, Yoshiharu Matsuura, Naoki Hiramatsu, Tetsuo Takehara

Hepatology　Vol. 65　No. 1　p. 18-31　2017/01/01　Research paper (scientific journal)

Inhibitory effect of CDK9 inhibitor FIT-039 on hepatitis B virus propagation

Tomohisa Tanaka, Kaori Okuyama-Dobashi, Shuko Murakami, Wenjia Chen, Toru Okamoto, Keiji Ueda, Takamitsu Hosoya, Yoshiharu Matsuura, Akihide Ryo, Yasuhito Tanaka, Masatoshi Hagiwara, Kohji Moriishi

Antiviral Research　Vol. 133　p. 156-164　2016/09/01　Research paper (scientific journal)

Unique Requirement for ESCRT Factors in Flavivirus Particle Formation on the Endoplasmic Reticulum

Keisuke Tabata, Masaru Arimoto, Masashi Arakawa, Atsuki Nara, Kazunobu Saito, Hiroko Omori, Arisa Arai, Tomohiro Ishikawa, Eiji Konishi, Ryosuke Suzuki, Yoshiharu Matsuura, Eiji Morita

Cell Reports　Vol. 16　No. 9　p. 2339-2347　2016/08/30　Research paper (scientific journal)

TRC8-dependent degradation of hepatitis C virus immature core protein regulates viral propagation and pathogenesis

Sayaka Aizawa, Toru Okamoto, Yukari Sugiyama, Takahisa Kouwaki, Ayano Ito, Tatsuya Suzuki, Chikako Ono, Takasuke Fukuhara, Masahiro Yamamoto, Masayasu Okochi, Nobuhiko Hiraga, Michio Imamura, Kazuaki Chayama, Ryosuke Suzuki, Ikuo Shoji, Kohji Moriishi, Kyoji Moriya, Kazuhiko Koike, Yoshiharu Matsuura

Nature Communications　Vol. 7　2016/05/04　Research paper (scientific journal)

Lipoprotein Receptors Redundantly Participate in Entry of Hepatitis C Virus

Satomi Yamamoto, Takasuke Fukuhara, Chikako Ono, Kentaro Uemura, Yukako Kawachi, Mai Shiokawa, Hiroyuki Mori, Masami Wada, Ryoichi Shima, Toru Okamoto, Nobuhiko Hiraga, Ryosuke Suzuki, Kazuaki Chayama, Takaji Wakita, Yoshiharu Matsuura

PLoS Pathogens　Vol. 12　No. 5　2016/05　Research paper (scientific journal)

Arid5a regulates naive CD4⁺ T cell fate through selective stabilization of Stat3 mRNA

Kazuya Masuda, Barry Ripley, Kishan Kumar Nyati, Praveen Kumar Dubey, Mohammad Mahabub Uz Zaman, Hamza Hanieh, Mitsuru Higa, Kazuo Yamashita, Daron M. Standley, Tsukasa Mashima, Masato Katahira, Toru Okamoto, Yoshiharu Matsuura, Osamu Takeuchi, Tadamitsu Kishimoto

Journal of Experimental Medicine　Vol. 213　No. 4　p. 605-619　2016/04　Research paper (scientific journal)

Production of hepatitis E virus-like particles presenting multiple foreign epitopes by co-infection of recombinant baculoviruses

Ryoichi Shima, Tian Cheng Li, Yutaka Sendai, Chikako Kataoka, Yoshio Mori, Takayuki Abe, Naokazu Takeda, Toru Okamoto, Yoshiharu Matsuura

Scientific Reports　Vol. 6　2016/02/24　Research paper (scientific journal)

Reverse Genetics for Fusogenic Bat-Borne Orthoreovirus Associated with Acute Respiratory Tract Infections in Humans: Role of Outer Capsid Protein σC in Viral Replication and Pathogenesis

Takahiro Kawagishi, Yuta Kanai, Hideki Tani, Masayuki Shimojima, Masayuki Saijo, Yoshiharu Matsuura, Takeshi Kobayashi

PLoS Pathogens　Vol. 12　No. 2　2016/02　Research paper (scientific journal)

Structural proteins of HCV and biological functions

Kohji Moriishi, Yoshiharu Matsuura

Hepatitis C Virus I: Cellular and Molecular Virology　p. 105-127　2016/01/01　Part of collection (book)

Human cathelicidin compensates for the role of apolipoproteins in hepatitis C virus infectious particle formation

Francesc Puig-Basagoiti, Takasuke Fukuhara, Tomokazu Tamura, Chikako Ono, Kentaro Uemura, Yukako Kawachi, Satomi Yamamoto, Hiroyuki Mori, Takeshi Kurihara, Toru Okamoto, Hideki Aizaki, Yoshiharu Matsuura

Journal of Virology　Vol. 90　No. 19　p. 8464-8477　2016　Research paper (scientific journal)

Indoleamine-2,3-dioxygenase as an effector and an indicator of protective immune responses in patients with acute hepatitis B

Sachiyo Yoshio, Masaya Sugiyama, Hirotaka Shoji, Yohei Mano, Eiji Mita, Toru Okamoto, Yoshiharu Matsuura, Alato Okuno, Osamu Takikawa, Masashi Mizokami, Tatsuya Kanto

Hepatology　Vol. 63　No. 1　p. 83-94　2016/01/01　Research paper (scientific journal)

Hepatocyte factor JMJD5 regulates hepatitis B virus replication through interaction with HBx

Takahisa Kouwaki, Toru Okamoto, Ayano Ito, Yukari Sugiyama, Kazuo Yamashita, Tatsuya Suzuki, Shinji Kusakabe, Junki Hirano, Takasuke Fukuhara, Atsuya Yamashita, Kazunobu Saito, Daisuke Okuzaki, Koichi Watashi, Masaya Sugiyama, Sachiyo Yoshio, Daron M. Standley, Tatsuya Kanto, Masashi Mizokami, Kohji Moriishi, Yoshiharu Matsuura

Journal of Virology　Vol. 90　No. 7　p. 3530-3542　2016　Research paper (scientific journal)

Hepatitis virus related viruses

Takasuke Fukuhara, Yoshiharu Matsuura

Nihon rinsho. Japanese journal of clinical medicine　Vol. 73　p. 30-35　2015/12/01　Research paper (scientific journal)

Hepatitis B virus efficiently infects non-adherent hepatoma cells via human sodium taurocholate cotransporting polypeptide

Kaori Okuyama-Dobashi, Hirotake Kasai, Tomohisa Tanaka, Atsuya Yamashita, Jun Yasumoto, Wenjia Chen, Toru Okamoto, Shinya Maekawa, Koichi Watashi, Takaji Wakita, Akihide Ryo, Tetsuro Suzuki, Yoshiharu Matsuura, Nobuyuki Enomoto, Kohji Moriishi

Scientific Reports　Vol. 5　2015/11/23　Research paper (scientific journal)

Involvement of FKBP6 in hepatitis C virus replication

Hirotake Kasai, Kunihiro Kawakami, Hiromasa Yokoe, Kentaro Yoshimura, Masanori Matsuda, Jun Yasumoto, Shinya Maekawa, Atsuya Yamashita, Tomohisa Tanaka, Masanori Ikeda, Nobuyuki Kato, Toru Okamoto, Yoshiharu Matsuura, Naoya Sakamoto, Nobuyuki Enomoto, Sen Takeda, Hideki Fujii, Masayoshi Tsubuki, Masami Kusunoki, Kohji Moriishi

Scientific Reports　Vol. 5　No. 5　2015/11/16　Research paper (scientific journal)

Long-term viral shedding and viral genome mutation in norovirus infection

Tatsuya Miyoshi, Kiyoko Uchino, Hisayoshi Yoshida, Kazushi Motomura, Naokazu Takeda, Yoshiharu Matsuura, Tomoyuki Tanaka

Journal of Medical Virology　Vol. 87　No. 11　p. 1872-1880　2015/11/01　Research paper (scientific journal)

Roles of lipoprotein receptors in the entry of hepatitis C virus

Takasuke Fukuhara, Satomi Yamamoto, Chikako Ono, Hiroyuki Mori, Francesc Puig-Basagoiti, Toru Okamoto, Yoshiharu Matsuura

2015/10　Research paper (international conference proceedings)

Roles of Lipoproteins and Apolipoproteins in Particle Formation of Hepatitis C Virus

Takasuke Fukuhara, Chikako Ono, Francesc Puig-Basagoiti, Yoshiharu Matsuura

Trends in Microbiology　Vol. 23　No. 10　p. 618-629　2015/10

Role of zinc-finger anti-viral protein in host defense against Sindbis virus

Tatsuya Kozaki, Michihiro Takahama, Takuma Misawa, Yoshiharu Matsuura, Shizuo Akira, Tatsuya Saitoh

International Immunology　Vol. 27　No. 7　p. 357-364　2015/07/01　Research paper (scientific journal)

Novel sex-dependent differentially methylated regions are demethylated in adult male mouse livers

Shuhei Ito, Keiji Hirabayashi, Kohji Moriishi, Yasuhisa Matsui, Kyoji Moriya, Kazuhiko Koike, Yoshiharu Matsuura, Kunio Shiota, Shintaro Yagi

Biochemical and Biophysical Research Communications　Vol. 462　No. 4　p. 332-338　2015/06/12　Research paper (scientific journal)

Anti-HCV effect of Lentinula edodes mycelia solid culture extracts and low-molecular-weight lignin

Koji Matsuhisa, Seiji Yamane, Toru Okamoto, Akihiro Watari, Masuo Kondoh, Yoshiharu Matsuura, Kiyohito Yagi

Biochemical and Biophysical Research Communications　Vol. 462　No. 1　p. 52-57　2015/05/28　Research paper (scientific journal)

Tightly regulated expression of autographa californica multicapsid nucleopolyhedrovirus immediate early genes emerges from their interactions and possible collective behaviors

Chikako Ono, Masanao Sato, Hitomi Taka, Shin Ichiro Asano, Yoshiharu Matsuura, Hisanori Bando

PLoS ONE　Vol. 10　No. 3　2015/03/27　Research paper (scientific journal)

[Lifecycle of HCV and point of action of the anti-HCV drugs]

Yoshiharu Matsuura

Nihon rinsho. Japanese journal of clinical medicine　Vol. 73　No. 2　p. 184-188　2015/02/01　Research paper (scientific journal)

Kinase-interacting substrate screening is a novel method to identify kinase substrates

Mutsuki Amano, Tomonari Hamaguchi, Md Hasanuzzaman Shohag, Kei Kozawa, Katsuhiro Kato, Xinjian Zhang, Yoshimitsu Yura, Yoshiharu Matsuura, Chikako Kataoka, Tomoki Nishioka, Kozo Kaibuchi

Journal of Cell Biology　Vol. 209　No. 6　p. 895-912　2015　Research paper (scientific journal)

Roles of lipoprotein and apolipoprotein in HCV infection

Takasuke Fukuhara, Yoshiharu Matsuura

Uirusu　Vol. 65　No. 2　p. 269-276　2015

Host factors involved in the propagation and pathogenesis of hepatitis C Virus

Toru Okamoto, Yoshiharu Matsuura

Inflammation and Immunity in Cancer　p. 103-108　2015/01/01　Part of collection (book)

Alternative endocytosis pathway for productive entry of hepatitis C virus

Mami Matsuda, Ryosuke Suzuki, Chikako Kataoka, Koichi Watashi, Hideki Aizaki, Nobuyuki Kato, Yoshiharu Matsuura, Tetsuro Suzuki, Takaji Wakita

Journal of General Virology　Vol. 95　No. Pt 12　p. 2658-2667　2014/12/01　Research paper (scientific journal)

Amphipathic α-Helices in Apolipoproteins Are Crucial to the Formation of Infectious Hepatitis C Virus Particles

Takasuke Fukuhara, Masami Wada, Shota Nakamura, Chikako Ono, Mai Shiokawa, Satomi Yamamoto, Takashi Motomura, Toru Okamoto, Daisuke Okuzaki, Masahiro Yamamoto, Izumu Saito, Takaji Wakita, Kazuhiko Koike, Yoshiharu Matsuura

PLoS Pathogens　Vol. 10　No. 12　2014/12/01　Research paper (scientific journal)

Role of mouse and human autophagy proteins in IFN-γ-induced cell-autonomous responses against Toxoplasma gondii

Jun Ohshima, Youngae Lee, Miwa Sasai, Tatsuya Saitoh, Ji Su Ma, Naganori Kamiyama, Yoshiharu Matsuura, Suh Pann-Ghill, Mikako Hayashi, Shigeyuki Ebisu, Kiyoshi Takeda, Shizuo Akira, Masahiro Yamamoto

Journal of Immunology　Vol. 192　No. 7　p. 3328-3335　2014/04　Research paper (scientific journal)

Innate immune response induced by baculovirus attenuates transgene expression in mammalian cells

Chikako Ono, Akinori Ninomiya, Satomi Yamamoto, Takayuki Abe, Xiauyu Wen, Takasuke Fukuhara, Miwa Sasai, Masahiro Yamamoto, Tatsuya Saitoh, Takashi Satoh, Taro Kawai, Ken J. Ishii, Shizuo Akira, Toru Okamoto, Yoshiharu Matsuura

Journal of Virology　Vol. 88　No. 4　p. 2157-2167　2014/02　Research paper (scientific journal)

Binding of HSV-1 glycoprotein K (gK) to signal peptide peptidase (SPP) is required for virus infectivity

Sariah J. Allen, Kevin R. Mott, Yoshiharu Matsuura, Kohji Moriishi, Konstantin G. Kousoulas, Homayon Ghiasi

PLoS ONE　Vol. 9　No. 1　2014/01/20　Research paper (scientific journal)

Detection of hepatitis C virus by single-step hairpin primer RT-PCR

Fumie Takei, Hideki Tani, Yoshiharu Matsuura, Kazuhiko Nakatani

Bioorganic and Medicinal Chemistry Letters　Vol. 24　No. 1　p. 394-396　2014/01/01　Research paper (scientific journal)

Hallmarks of hepatitis C virus in equine hepacivirus

Tomohisa Tanaka, Hirotake Kasai, Atsuya Yamashita, Kaori Okuyama-Dobashi, Jun Yasumoto, Shinya Maekawa, Nobuyuki Enomoto, Toru Okamoto, Yoshiharu Matsuura, Masami Morimatsu, Noboru Manabe, Kazuhiko Ochiai, Kazuto Yamashita, Kohji Moriishi

Journal of Virology　Vol. 88　No. 22　p. 13352-13366　2014　Research paper (scientific journal)

Reduced-dose telaprevir-based triple antiviral therapy for recurrent hepatitis C after living donor liver transplantation

Toru Ikegami, Tomoharu Yoshizumi, Masaki Kato, Satomi Yamamoto, Takasuke Fukuhara, Yoshiharu Matsuura, Shota Nakamura, Shinji Itoh, Ken Shirabe, Yoshihiko Maehara

Transplantation　Vol. 98　No. 9　p. 994-999　2014　Research paper (scientific journal)

Novel permissive cell lines for complete propagation of hepatitis C virus

Mai Shiokawa, Takasuke Fukuhara, Chikako Ono, Satomi Yamamoto, Toru Okamoto, Noriyuki Watanabe, Takaji Wakita, Yoshiharu Matsuura

Journal of Virology　Vol. 88　No. 10　p. 5578-5594　2014　Research paper (scientific journal)

Ca²⁺/S100 proteins regulate HCV virus NS5A-FKBP8/FKBP38 interaction and HCV virus RNA replication

Joji Tani, Seiko Shimamoto, Kyoko Mori, Nobuyuki Kato, Kohji Moriishi, Yoshiharu Matsuura, Hiroshi Tokumitsu, Mitsumasa Tsuchiya, Tomohito Fujimoto, Kiyohito Kato, Hisaaki Miyoshi, Tsutomu Masaki, Ryoji Kobayashi

Liver International　Vol. 33　No. 7　p. 1008-1018　2013/08　Research paper (scientific journal)

Signal Peptidase Complex Subunit 1 Participates in the Assembly of Hepatitis C Virus through an Interaction with E2 and NS2

Ryosuke Suzuki, Mami Matsuda, Koichi Watashi, Hideki Aizaki, Yoshiharu Matsuura, Takaji Wakita, Tetsuro Suzuki

PLoS Pathogens　Vol. 9　No. 8　2013/08　Research paper (scientific journal)

Understanding the biological context of NS5A-host interactions in HCV infection: A network-based approach

Lokesh P. Tripathi, Hiroto Kambara, Yi An Chen, Yorihiro Nishimura, Kohji Moriishi, Toru Okamoto, Eiji Morita, Takayuki Abe, Yoshio Mori, Yoshiharu Matsuura, Kenji Mizuguchi

Journal of Proteome Research　Vol. 12　No. 6　p. 2537-2551　2013/06/07　Research paper (scientific journal)

Human blood dendritic cell antigen 3 (BDCA3)⁺ dendritic cells are a potent producer of interferon-λ in response to hepatitis C virus

Sachiyo Yoshio, Tatsuya Kanto, Shoko Kuroda, Tokuhiro Matsubara, Koyo Higashitani, Naruyasu Kakita, Hisashi Ishida, Naoki Hiramatsu, Hiroaki Nagano, Masaya Sugiyama, Kazumoto Murata, Takasuke Fukuhara, Yoshiharu Matsuura, Norio Hayashi, Masashi Mizokami, Tetsuo Takehara

Hepatology　Vol. 57　No. 5　p. 1705-1715　2013/05　Research paper (scientific journal)

Role of miR-122 and lipid metabolism in HCV infection

Takasuke Fukuhara, Yoshiharu Matsuura

Journal of Gastroenterology　Vol. 48　No. 2　p. 169-176　2013/02

Japanese encephalitis virus core protein inhibits stress granule formation through an interaction with Caprin-1 and facilitates viral propagation

Hiroshi Katoh, Toru Okamoto, Takasuke Fukuhara, Hiroto Kambara, Eiji Morita, Yoshio Mori, Wataru Kamitani, Yoshiharu Matsuura

Journal of Virology　Vol. 87　No. 1　p. 489-502　2013/01　Research paper (scientific journal)

Ifit1 inhibits japanese encephalitis virus replication through binding to 5= capped 2'-o unmethylated RNA

Taishi Kimura, Hiroshi Katoh, Hisako Kayama, Hiroyuki Saiga, Megumi Okuyama, Toru Okamoto, Eiji Umemoto, Yoshiharu Matsuur, Masahiro Yamamoto, Kiyoshi Takeda

Journal of Virology　Vol. 87　No. 18　p. 9997-10003　2013　Research paper (scientific journal)

Trans-complemented hepatitis C virus particles as a versatile tool for study of virus assembly and infection

Ryosuke Suzuki, Kenji Saito, Takanobu Kato, Masayuki Shirakura, Daisuke Akazawa, Koji Ishii, Hideki Aizaki, Yumi Kanegae, Yoshiharu Matsuura, Izumu Saito, Takaji Wakita, Tetsuro Suzuki

Virology　Vol. 432　No. 1　p. 29-38　2012/10/10　Research paper (scientific journal)

Severe acute respiratory syndrome coronavirus nsp1 facilitates efficient propagation in cells through a specific translational shutoff of host mrna

Tomohisa Tanaka, Wataru Kamitani, Marta L. DeDiego, Luis Enjuanes, Yoshiharu Matsuura

Journal of Virology　Vol. 86　No. 20　p. 11128-11137　2012/10　Research paper (scientific journal)

Proteomic analysis of hepatitis C virus (HCV) core protein transfection and host regulator PA28γ knockout in HCV pathogenesis: A network-based study

Lokesh P. Tripathi, Hiroto Kambara, Kohji Moriishi, Eiji Morita, Takayuki Abe, Yoshio Mori, Yi An Chen, Yoshiharu Matsuura, Kenji Mizuguchi

Journal of Proteome Research　Vol. 11　No. 7　p. 3664-3679　2012/07/06　Research paper (scientific journal)

The inositol 5-phosphatase SHIP2 is an effector of RhoA and is involved in cell polarity and migration

Katsuhiro Kato, Tsubasa Yazawa, Kentaro Taki, Kazutaka Mori, Shujie Wang, Tomoki Nishioka, Tomonari Hamaguchi, Toshiki Itoh, Tadaomi Takenawa, Chikako Kataoka, Yoshiharu Matsuura, Mutsuki Amano, Toyoaki Murohara, Kozo Kaibuchi

Molecular Biology of the Cell　Vol. 23　No. 13　p. 2593-2604　2012/07/01　Research paper (scientific journal)

[miR-122 participates in the cell tropism of hepatitis C virus].

Takasuke Fukuhara, Yoshiharu Matsuura

Uirusu　Vol. 62　No. 1　p. 1-8　2012/06

CD44 Participates in IP-10 Induction in Cells in Which Hepatitis C Virus RNA Is Replicating, through an Interaction with Toll-Like Receptor 2 and Hyaluronan

Takayuki Abe, Takasuke Fukuhara, Xiauyu Wen, Akinori Ninomiya, Kohji Moriishi, Yoshihiko Maehara, Osamu Takeuchi, Taro Kawai, Shizuo Akira, Yoshiharu Matsuura

Journal of Virology　Vol. 86　No. 11　p. 6159-6170　2012/06　Research paper (scientific journal)

Specific interaction of the envelope glycoproteins E1 and E2 with liver heparan sulfate involved in the tissue tropismatic infection by hepatitis C virus

Fumi Kobayashi, Shuhei Yamada, Shuhei Taguwa, Chikako Kataoka, Satomi Naito, Yoshiki Hama, Hideki Tani, Yoshiharu Matsuura, Kazuyuki Sugahara

Glycoconjugate Journal　Vol. 29　No. 4　p. 211-220　2012/05　Research paper (scientific journal)

Upregulation of nuclear PA28γ expression in cirrhosis and hepatocellular carcinoma

Motoi Kondo, Kohji Moriishi, Hiroshi Wada, Takehiro Noda, Shigeru Marubashi, Kenichi Wakasa, Yoshiharu Matsuura, Yuichiro Doki, Masaki Mori, Hiroaki Nagano

Experimental and Therapeutic Medicine　Vol. 3　No. 3　p. 379-385　2012/03　Research paper (scientific journal)

Baculovirus GP64-mediated entry into mammalian cells

Chikako Kataoka, Yuuki Kaname, Shuhei Taguwa, Takayuki Abe, Takasuke Fukuhara, Hideki Tani, Kohji Moriishi, Yoshiharu Matsuura

Journal of Virology　Vol. 86　No. 5　p. 2610-2620　2012/03　Research paper (scientific journal)

Establishment of a novel permissive cell line for the propagation of hepatitis C virus by expression of microRNA miR122

Hiroto Kambara, Takasuke Fukuhara, Mai Shiokawa, Chikako Ono, Yuri Ohara, Wataru Kamitani, Yoshiharu Matsuura

Journal of Virology　Vol. 86　No. 3　p. 1382-1393　2012/02　Research paper (scientific journal)

Arabidopsis β1,2-xylosyltransferase: Substrate specificity and participation in the plant-specific N-glycosylation pathway

Hiroyuki Kajiura, Toru Okamoto, Ryo Misaki, Yoshiharu Matsuura, Kazuhito Fujiyama

Journal of Bioscience and Bioengineering　Vol. 113　No. 1　p. 48-54　2012/01　Research paper (scientific journal)

Expression of microRNA miR-122 facilitates an efficient replication in nonhepatic cells upon infection with hepatitis C virus

Takasuke Fukuhara, Hiroto Kambara, Mai Shiokawa, Chikako Ono, Hiroshi Katoh, Eiji Morita, Daisuke Okuzaki, Yoshihiko Maehara, Kazuhiko Koike, Yoshiharu Matsuura

Journal of Virology　Vol. 86　No. 15　p. 7918-7933　2012　Research paper (scientific journal)

Exploitation of lipid components by viral and host proteins for hepatitis C virus infection

Kohji Moriishi, Yashiharu Matsuura

Frontiers in Microbiology　Vol. 3　No. FEB　2012　Research paper (scientific journal)

Development and applications of VSV vectors based on cell tropism

Hideki Tani, Shigeru Morikawa, Yoshiharu Matsuura

Frontiers in Microbiology　Vol. 2　No. JAN　2012　Research paper (scientific journal)

Use of human hepatocyte-like cells derived from induced pluripotent stem cells as a model for hepatocytes in hepatitis C virus infection

Takeshi Yoshida, Kazuo Takayama, Masuo Kondoh, Fuminori Sakurai, Hideki Tani, Naoya Sakamoto, Yoshiharu Matsuura, Hiroyuki Mizuguchi, Kiyohito Yagi

Biochemical and Biophysical Research Communications　Vol. 416　No. 1-2　p. 119-124　2011/12/09　Research paper (scientific journal)

Dysfunction of autophagy participates in vacuole formation and cell death in cells replicating Hepatitis C virus

Shuhei Taguwa, Hiroto Kambara, Naonobu Fujita, Takeshi Noda, Tamotsu Yoshimori, Kazuhiko Koike, Kohji Moriishi, Yoshiharu Matsuura

Journal of Virology　Vol. 85　No. 24　p. 13185-13194　2011/12　Research paper (scientific journal)

Heterogeneous nuclear ribonucleoprotein A2 participates in the replication of japanese encephalitis virus through an interaction with viral proteins and RNA

Hiroshi Katoh, Yoshio Mori, Hiroto Kambara, Takayuki Abe, Takasuke Fukuhara, Eiji Morita, Kohji Moriishi, Wataru Kamitani, Yoshiharu Matsuura

Journal of Virology　Vol. 85　No. 21　p. 10976-10988　2011/11　Research paper (scientific journal)

Role of the Endoplasmic Reticulum-associated Degradation (ERAD) pathway in degradation of hepatitis C virus envelope proteins and production of virus particles

Mohsan Saeed, Ryosuke Suzuki, Noriyuki Watanabe, Takahiro Masaki, Mitsunori Tomonaga, Amir Muhammad, Takanobu Kato, Yoshiharu Matsuura, Haruo Watanabe, Takaji Wakita, Tetsuro Suzuki

Journal of Biological Chemistry　Vol. 286　No. 43　p. 37264-37273　2011/10/28　Research paper (scientific journal)

ATF6β is a host cellular target of the Toxoplasma gondii virulence factor ROP18

Masahiro Yamamoto, Ji Su Ma, Christina Mueller, Naganori Kamiyama, Hiroyuki Saiga, Emi Kubo, Taishi Kimura, Toru Okamoto, Megumi Okuyama, Hisako Kayama, Kisaburo Nagamune, Seiji Takashima, Yoshiharu Matsuura, Dominique Soldati-Favre, Kiyoshi Takeda

Journal of Experimental Medicine　Vol. 208　No. 7　p. 1533-1546　2011/07/04　Research paper (scientific journal)

Will there Be an HCV meeting in 2020? Summary of the 17th international meeting on hepatitis C virus and related viruses

Takaji Wakita, Tetsuro Suzuki, Matthew J. Evans, Kunitada Shimotohno, Kazuaki Chayama, Yoshiharu Matsuura, Makoto Hijikata, Kohji Moriishi, Tsukasa Seya, Nobuyuki Enomoto, Kazuhiko Koike, Nobuyuki Kato, Tatsuya Kanto, Hak Hotta

Gastroenterology　Vol. 141　No. 1　p. e1-5　2011/07　Research paper (international conference proceedings)

[Entry mechanisms of HCV].

Hideki Tani, Yoshiharu Matsuura

Nihon rinsho. Japanese journal of clinical medicine　Vol. 69 Suppl 4　p. 47-51　2011/05　Research paper (scientific journal)

Intracellular delivery of serum-derived hepatitis C virus

Takasuke Fukuhara, Hideki Tani, Mai Shiokawa, Yukinori Goto, Takayuki Abe, Akinobu Taketomi, Ken Shirabe, Yoshihiko Maehara, Yoshiharu Matsuura

Microbes and Infection　Vol. 13　No. 4　p. 405-412　2011/04　Research paper (scientific journal)

Involvement of cyclophilin B in the replication of Japanese encephalitis virus

Hiroto Kambara, Hideki Tani, Yoshio Mori, Takayuki Abe, Hiroshi Katoh, Takasuke Fukuhara, Shuhei Taguwa, Kohji Moriishi, Yoshiharu Matsuura

Virology　Vol. 412　No. 1　p. 211-219　2011/03/30　Research paper (scientific journal)

Pathogenesis of lipid metabolism disorder in hepatitis C: Polyunsaturated fatty acids counteract lipid alterations induced by the core protein

Hideyuki Miyoshi, Kyoji Moriya, Takeya Tsutsumi, Seiko Shinzawa, Hajime Fujie, Yoshizumi Shintani, Hidetake Fujinaga, Koji Goto, Toru Todoroki, Tetsuro Suzuki, Tatsuo Miyamura, Yoshiharu Matsuura, Hiroshi Yotsuyanagi, Kazuhiko Koike

Journal of Hepatology　Vol. 54　No. 3　p. 432-438　2011/03　Research paper (scientific journal)

Chaperonin TRiC/CCT participates in replication of hepatitis C virus genome via interaction with the viral NS5B protein

Yasushi Inoue, Hideki Aizaki, Hiromichi Hara, Mami Matsuda, Tomomi Ando, Tetsu Shimoji, Kyoko Murakami, Takahiro Masaki, Ikuo Shoji, Sakae Homma, Yoshiharu Matsuura, Tatsuo Miyamura, Takaji Wakita, Tetsuro Suzuki

Virology　Vol. 410　No. 1　p. 38-47　2011/02/05　Research paper (scientific journal)

Elimination of hepatitis C virus from hepatocytes by a selective activation of therapeutic molecules

Xiaoyu Wen, Takayuki Abe, Hiroshi Kukihara, Shuhei Taguwa, Yoshio Mori, Hideki Tani, Nobuyuki Kato, Tetsuro Suzuki, Masashi Tatsumi, Kohji Moriishi, Yoshiharu Matsuura

PLoS ONE　Vol. 6　No. 1　2011　Research paper (scientific journal)

Network based analysis of hepatitis C virus Core and NS4B protein interactions

Lokesh P. Tripathi, Chikako Kataoka, Shuhei Taguwa, Kohji Moriishi, Yoshio Mori, Yoshiharu Matsuura, Kenji Mizuguchi

Molecular BioSystems　Vol. 6　No. 12　p. 2539-2553　2010/12　Research paper (scientific journal)

The ubiquitin ligase TRIM56 regulates innate immune responses to intracellular double-stranded DNA

Tetsuo Tsuchida, Jian Zou, Tatsuya Saitoh, Himanshu Kumar, Takayuki Abe, Yoshiharu Matsuura, Taro Kawai, Shizuo Akira

Immunity　Vol. 33　No. 5　p. 765-776　2010/11/24　Research paper (scientific journal)

Variants in IL28B in liver recipients and donors correlate with response to peg-interferon and ribavirin therapy for recurrent hepatitis C

Takasuke Fukuhara, Akinobu Taketomi, Takashi Motomura, Shinji Okano, Akinori Ninomiya, Takayuki Abe, Hideaki Uchiyama, Yuji Soejima, Ken Shirabe, Yoshiharu Matsuura, Yoshihiko Maehara

Gastroenterology　Vol. 139　No. 5　p. 1577-85, 1585.e1　2010/11　Research paper (scientific journal)

Peripheral B cells may serve as a reservoir for persistent hepatitis C virus infection

Masahiko Ito, Atsuko Masumi, Keiko Mochida, Hiroshi Kukihara, Kohji Moriishi, Yoshiharu Matsuura, Kazunari Yamaguchi, Toshiaki Mizuochi

Journal of Innate Immunity　Vol. 2　No. 6　p. 607-617　2010/10　Research paper (scientific journal)

Involvement of PA28γ in the propagation of hepatitis C virus

Kohji Moriishi, Ikuo Shoji, Yoshio Mori, Ryosuke Suzuki, Tetsuro Suzuki, Chikako Kataoka, Yoshiharu Matsuura

Hepatology　Vol. 52　No. 2　p. 411-420　2010/08　Research paper (scientific journal)

Production of infectious hepatitis C virus by using RNA polymerase I-mediated transcription

Takahiro Masaki, Ryosuke Suzuki, Mohsan Saeed, Ken Ichi Mori, Mami Matsuda, Hideki Aizaki, Koji Ishii, Noboru Maki, Tatsuo Miyamura, Yoshiharu Matsuura, Takaji Wakita, Tetsuro Suzuki

Journal of Virology　Vol. 84　No. 11　p. 5824-5835　2010/06　Research paper (scientific journal)

Acquisition of complement resistance through incorporation of CD55/decay-accelerating factor into viral particles bearing baculovirus GP64

Yuuki Kaname, Hideki Tani, Chikako Kataoka, Mai Shiokawa, Shuhei Taguwa, Takayuki Abe, Kohji Moriishi, Taroh Kinoshita, Yoshiharu Matsuura

Journal of Virology　Vol. 84　No. 7　p. 3210-3219　2010/04　Research paper (scientific journal)

Establishment of an indicator cell system for hepatitis C virus

Yoshinori Tanaka, Yoshio Mori, Hideki Tani, Takayuki Abe, Kohji Moriishi, Hirotatsu Kojima, Tetsuo Nagano, Takayoshi Okabe, Tetsuro Suzuki, Masashi Tatsumi, Yoshiharu Matsuura

Microbiology and Immunology　Vol. 54　No. 4　p. 206-220　2010/04　Research paper (scientific journal)

Tellimagrandin I, HCV invasion inhibitor from Rosae Rugosae Flos

Satoru Tamura, Gang Ming Yang, Natsuko Yasueda, Yoshiharu Matsuura, Yasumasa Komoda, Nobutoshi Murakami

Bioorganic and Medicinal Chemistry Letters　Vol. 20　No. 5　p. 1598-1600　2010/03/01　Research paper (scientific journal)

Involvement of ceramide in the propagation of Japanese encephalitis virus

Hideki Tani, Mai Shiokawa, Yuuki Kaname, Hiroto Kambara, Yoshio Mori, Takayuki Abe, Kohji Moriishi, Yoshiharu Matsuura

Journal of Virology　Vol. 84　No. 6　p. 2798-2807　2010/03　Research paper (scientific journal)

Procyanidin B1 purified from Cinnamomi cortex suppresses hepatitis C virus replication

Shenwei Li, Eiichi N. Kodama, Yuuki Inoue, Hideki Tani, Yoshiharu Matsuura, Jing Zhang, Takashi Tanaka, Toshio Hattori

Antiviral Chemistry and Chemotherapy　Vol. 20　No. 6　p. 239-248　2010　Research paper (scientific journal)

Concanavalin a affinity chromatography for efficient baculovirus purification

Guan Yu Chen, Chi Yuan Chen, Margaret Dah Tsyr Chang, Yoshiharu Matsuura, Yu Chen Hu

Biotechnology Progress　Vol. 25　No. 6　p. 1669-1677　2009/11　Research paper (scientific journal)

Cochaperone activity of human butyrate-induced transcript 1 facilitates hepatitis C virus replication through an Hsp90-dependent pathway

Shuhei Taguwa, Hiroto Kambara, Hiroko Omori, Hideki Tani, Takayuki Abe, Yoshio Mori, Tetsuro Suzuki, Tamotsu Yoshimori, Kohji Moriishi, Yoshiharu Matsuura

Journal of Virology　Vol. 83　No. 20　p. 10427-10436　2009/10　Research paper (scientific journal)

Biological and immunological characteristics of hepatitis E virus-like particles based on the crystal structure

Tetsuo Yamashita, Yoshio Mori, Naoyuki Miyazaki, R. Holland Cheng, Masato Yoshimura, Hideaki Unno, Ryoichi Shima, Kohji Moriishi, Tomitake Tsukihara, Cheng Li Tian, Naokazu Takeda, Tatsuo Miyamura, Yoshiharu Matsuura

Proceedings of the National Academy of Sciences of the United States of America　Vol. 106　No. 31　p. 12986-12991　2009/08/04　Research paper (scientific journal)

Human VAP-C negatively regulates hepatitis C virus propagation

Hiroshi Kukihara, Kohji Moriishi, Shuhei Taguwa, Hideki Tani, Takayuki Abe, Yoshio Mori, Tetsuro Suzuki, Takasuke Fukuhara, Akinobu Taketomi, Yoshihiko Maehara, Yoshiharu Matsuura

Journal of Virology　Vol. 83　No. 16　p. 7959-7969　2009/08　Research paper (scientific journal)

Baculovirus induces type I interferon production through toll-like receptor-dependent and -independent pathways in a cell-type-specific manner

Takayuki Abe, Yuuki Kaname, Xiaoyu Wen, Hideki Tani, Kohji Moriishi, Satoshi Uematsu, Osamu Takeuchi, Ken J. Ishii, Taro Kawai, Shizuo Akira, Yoshiharu Matsuura

Journal of Virology　Vol. 83　No. 15　p. 7629-7640　2009/08　Research paper (scientific journal)

Mobile DHHC palmitoylating enzyme mediates activity-sensitive synaptic targeting of PSD-95

Jun Noritake, Yuko Fukata, Tsuyoshi Iwanaga, Naoki Hosomi, Ryouhei Tsutsumi, Naoto Matsuda, Hideki Tani, Hiroko Iwanari, Yasuhiro Mochizuki, Tatsuhiko Kodama, Yoshiharu Matsuura, David S. Bredt, Takao Hamakubo, Masaki Fukata

Journal of Cell Biology　Vol. 186　No. 1　p. 147-160　2009/07/13　Research paper (scientific journal)

[Interface between viruses and host].

Yoshiharu Matsuura

Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme　Vol. 54　No. 8 Suppl　p. 899-900　2009/06　Research paper (scientific journal)

Involvement of creatine kinase B in hepatitis C virus genome replication through interaction with the viral NS4A protein

Hiromichi Hara, Hideki Aizaki, Mami Matsuda, Fumiko Shinkai-Ouchi, Yasushi Inoue, Kyoko Murakami, Ikuo Shoji, Hayato Kawakami, Yoshiharu Matsuura, Michael M.C. Lai, Tatsuo Miyamura, Takaji Wakita, Tetsuro Suzuki

Journal of Virology　Vol. 83　No. 10　p. 5137-5147　2009/05　Research paper (scientific journal)

Proteasomal turnover of hepatitis C virus Core protein is regulated by two distinct mechanisms: A ubiquitin-dependent mechanism and a ubiquitin-independent but PA28γ-dependent mechanism

Ryosuke Suzuki, Kohji Moriishi, Kouichirou Fukuda, Masayuki Shirakura, Koji Ishii, Ikuo Shoji, Takaji Wakita, Tatsuo Miyamura, Yoshiharu Matsuura, Tetsuro Suzuki

Journal of Virology　Vol. 83　No. 5　p. 2389-2392　2009/03　Research paper (scientific journal)

Rho-kinase contributes to sustained RhoA activation through phosphorylation of p190A RhoGAP

Kazutaka Mori, Mutsuki Amano, Mikito Takefuji, Katsuhiro Kato, Yasuhiro Morita, Tomoki Nishioka, Yoshiharu Matsuura, Toyoaki Murohara, Kozo Kaibuchi

Journal of Biological Chemistry　Vol. 284　No. 8　p. 5067-5076　2009/02/20　Research paper (scientific journal)

Baculoviruses as vaccine vectors

Takayuki Abe, Hideki Tani, Yoshiharu Matsuura

Drug Delivery System　Vol. 24　No. 6　p. 608-615　2009　Research paper (scientific journal)

Baculovirus transduction of chondrocytes elicits interferon-α/ β and suppresses transgene expression

Hsiao Ping Lee, Yoshiharu Matsuura, Huang Chi Chen, Yen Lin Chen, Ching Kuang Chuang, Takayuki Abe, Shiaw Min Hwang, Hsiao Chiao Shiah, Yu Chen Hu

Journal of Gene Medicine　Vol. 11　No. 4　p. 302-312　2009　Research paper (scientific journal)

Tacrolimus ameliorates metabolic disturbance and oxidative stress caused by hepatitis C virus core protein: Analysis using mouse model and cultured cells

Kyoji Moriya, Hideyuki Miyoshi, Takeya Tsutsumi, Seiko Shinzawa, Hajime Fujie, Yoshizumi Shintani, Hiroshi Yotsuyanagi, Kohji Moriishi, Yoshiharu Matsuura, Tetsuro Suzuki, Tatsuo Miyamura, Kazuhiko Koike

American Journal of Pathology　Vol. 175　No. 4　p. 1515-1524　2009　Research paper (scientific journal)

Processing and pathogenicity of HCV core protein

Kohji Moriishi, Yoshio Mori, Yoshiharu Matsuura

Uirusu. Journal of virology　Vol. 58　No. 2　p. 183-190　2008/12

脂質のC型肝炎ウイルス感染における役割

相崎 英樹, 山本 真民, 原 弘道, 森川 賢一, 谷 英樹, 松浦 善治, 斎藤 恭子, 深澤 征義, 花田 賢太郎, 西島 正弘, 宮村 達男, 脇田 隆字, 鈴木 哲朗

日本生化学会大会・日本分子生物学会年会合同大会講演要旨集　Vol. 81回・31回　p. 2T20-6　2008/11

Interaction of hepatitis C virus nonstructural protein 5A with core protein is critical for the production of infectious virus particles

Takahiro Masaki, Ryosuke Suzuki, Kyoko Murakami, Hideki Aizaki, Koji Ishii, Asako Murayama, Tomoko Date, Yoshiharu Matsuura, Tatsuo Miyamura, Takaji Wakita, Tetsuro Suzuki

Journal of Virology　Vol. 82　No. 16　p. 7964-7976　2008/08　Research paper (scientific journal)

Baculovirus-mediated interferon alleviates dimethylnitrosamine-induced liver cirrhosis symptoms in a murine model

Y. Nishibe, H. Kaneko, H. Suzuki, T. Abe, Y. Matsuura, H. Takaku

Gene Therapy　Vol. 15　No. 13　p. 990-997　2008/07　Research paper (scientific journal)

Critical role of virion-associated cholesterol and sphingolipid in hepatitis C virus infection

Hideki Aizaki, Kenichi Morikawa, Masayoshi Fukasawa, Hiromichi Hara, Yasushi Inoue, Hideki Tani, Kyoko Saito, Masahiro Nishijima, Kentaro Hanada, Yoshiharu Matsuura, Michael M.C. Lai, Tatsuo Miyamura, Takaji Wakita, Tetsuro Suzuki

Journal of Virology　Vol. 82　No. 12　p. 5715-5724　2008/06　Research paper (scientific journal)

Crystallization and preliminary X-ray diffraction analysis of recombinant hepatitis e virus-like particle

Che Yen Wang, Naoyuki Miyazaki, Tetsuo Yamashita, Akifumi Higashiura, Atsushi Nakagawa, Tian Cheng Li, Naokazu Takeda, Li Xing, Erik Hjalmarsson, Claes Friberg, Der Ming Liou, Yen Jen Sung, Tomitake Tsukihara, Yoshiharu Matsuura, Tatsuo Miyamura, R. Holland Cheng

Acta Crystallographica Section F: Structural Biology and Crystallization Communications　Vol. 64　No. 4　p. 318-322　2008/03/29　Research paper (scientific journal)

Virus-cell interaction of HCV

Hideki Tani, Yasumasa Komoda, Chang Kwang Limn, Kensuke Suzuki, Kohji Moriishi, Tatsuo Miyamura, Yoshiharu Matsuura

Structure-Based Study of Viral Replication: (With CD-Rom)　p. 125-150　2008/01/01　Part of collection (book)

Establishment of an infectious genotype 1b hepatitis C virus clone in human hepatocyte chimeric mice

Takashi Kimura, Michio Imamura, Nobuhiko Hiraga, Tsuyoshi Hatakeyama, Daiki Miki, Chiemi Noguchi, Nami Mori, Masataka Tsuge, Shoichi Takahashi, Yoshifumi Fujimoto, Eiji Iwao, Hidenori Ochi, Hiromi Abe, Toshiro Maekawa, Keiko Arataki, Chise Tateno, Katsutoshi Yoshizato, Takaji Wakita, Toru Okamoto, Yoshiharu Matsuura, Kazuaki Chayama

Journal of General Virology　Vol. 89　No. 9　p. 2108-2113　2008　Research paper (scientific journal)

Hepatitis C virus core protein: Its coordinate roles with PA28γ in metabolic abnormality and carcinogenicity in the liver

Yoshio Mori, Kohji Moriishi, Yoshiharu Matsuura

International Journal of Biochemistry and Cell Biology　Vol. 40　No. 8　p. 1437-1442　2008

Pathogenesis of hepatitis C virus

Kohji Moriishi, Yoshiharu Matsuura

Uirusu. Journal of virology　Vol. 57　No. 2　p. 141-149　2007/12

Evaluation systems for anti-HCV drugs

Kohji Moriishi, Yoshiharu Matsuura

Advanced Drug Delivery Reviews　Vol. 59　No. 12　p. 1213-1221　2007/10/10

Enhanced TLR-mediated NF-IL6-dependent gene expression by Trib1 deficiency

Masahiro Yamamoto, Satoshi Uematsu, Toru Okamoto, Yoshiharu Matsuura, Shintaro Sato, Himanshu Kumar, Takashi Satoh, Tatsuya Saitoh, Kiyoshi Takeda, Ken J. Ishii, Osamu Takeuchi, Taro Kawai, Shizuo Akira

Journal of Experimental Medicine　Vol. 204　No. 9　p. 2233-2239　2007/09/03　Research paper (scientific journal)

Host factors involved in the replication of hepatitis C virus

Kohji Moriishi, Yoshiharu Matsuura

Reviews in Medical Virology　Vol. 17　No. 5　p. 343-354　2007/09

Entry mechanisms of hepatitis C virus

Hideki Tani, Yoshiharu Matsuura

Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme　Vol. 52　No. 10 Suppl　p. 1095-1100　2007/08

Prevalence of antibody to hepatitis e virus among wild sika deer, Cervus nippon, in Japan

Y. Matsuura, M. Suzuki, K. Yoshimatsu, J. Arikawa, I. Takashima, M. Yokoyama, H. Igota, K. Yamauchi, S. Ishida, D. Fukui, G. Bando, M. Kosuge, H. Tsunemitsu, C. Koshimoto, K. Sakae, M. Chikahira, S. Ogawa, T. Miyamura, N. Takeda, T. C. Li

Archives of Virology　Vol. 152　No. 7　p. 1375-1381　2007/07　Research paper (scientific journal)

IQGAP3, a novel effector of Rac1 and Cdc42, regulates neurite outgrowth

Shujie Wang, Takashi Watanabe, Jun Noritake, Masaki Fukuta, Takeshi Yoshimura, Norimichi Itoh, Takumi Harada, Masato Nakagawa, Yoshiharu Matsuura, Nariko Arimura, Kozo Kaibuchi

Journal of Cell Science　Vol. 120　No. 4　p. 567-577　2007/02/15　Research paper (scientific journal)

Dvl regulates endo- and exocytotic processes through binding to synaptotagmin

Shosei Kishida, Kozue Hamao, Makoto Inoue, Mamoru Hasegawa, Yoshiharu Matsuura, Katsuhiko Mikoshiba, Mitsunori Fukuda, Akira Kikuchi

Genes to Cells　Vol. 12　No. 1　p. 49-61　2007/01　Research paper (scientific journal)

Hepatitis C virus RNA replication is regulated by FKBP8 and Hsp90

Toru Okamoto, Yorihiro Nishimura, Tohru Ichimura, Kensuke Suzuki, Tatsuo Miyamura, Tetsuro Suzuki, Kohji Moriishi, Yoshiharu Matsuura

EMBO Journal　Vol. 25　No. 20　p. 5015-5025　2006/10/18　Research paper (scientific journal)

Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling

Masahiro Yamamoto, Toru Okamoto, Kiyoshi Takeda, Shintaro Sato, Hideki Sanjo, Satoshi Uematsu, Tatsuya Saitoh, Naoki Yamamoto, Hiroaki Sakurai, Ken J. Ishii, Shoji Yamaoka, Taro Kawai, Yoshiharu Matsuura, Osamu Takeuchi, Shizuo Akira

Nature Immunology　Vol. 7　No. 9　p. 962-970　2006/09　Research paper (scientific journal)

Production of infectious hepatitis C virus particles in three-dimensional cultures of the cell line carrying the genome-length dicistronic viral RNA of genotype 1b

Kyoko Murakami, Koji Ishii, Yousuke Ishihara, Sayaka Yoshizaki, Keiko Tanaka, Yasufumi Gotoh, Hideki Aizaki, Michinori Kohara, Hiroshi Yoshioka, Yuichi Mori, Noboru Manabe, Ikuo Shoji, Tetsutaro Sata, Ralf Bartenschlager, Yoshiharu Matsuura, Tatsuo Miyamura, Tetsuro Suzuki

Virology　Vol. 351　No. 2　p. 381-392　2006/08/01　Research paper (scientific journal)

Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

Hiroki Kato, Osamu Takeuchi, Shintaro Sato, Mitsutoshi Yoneyama, Masahiro Yamamoto, Kosuke Matsui, Satoshi Uematsu, Andreas Jung, Taro Kawai, Ken J. Ishii, Osamu Yamaguchi, Kinya Otsu, Tohru Tsujimura, Chang Sung Koh, Caetano Reis E Sousa, Yoshiharu Matsuura, Takashi Fujita, Shizuo Akira

Nature　Vol. 441　No. 1　p. 101-105　2006/05/04　Research paper (scientific journal)

Down-regulation of the internal ribosome entry site (IRES)-mediated translation of the hepatitis C virus: Critical role of binding of the stem-loop IIId domain of IRES and the viral core protein

Takashi Shimoike, Chika Koyama, Kyoko Murakami, Ryosuke Suzuki, Yoshiharu Matsuura, Tatsuo Miyamura, Tetsuro Suzuki

Virology　Vol. 345　No. 2　p. 434-445　2006/02/20　Research paper (scientific journal)

Characterization of HCV-like particles produced in a human hepatoma cell line by a recombinant baculovirus

Eiko Matsuo, Hideki Tani, Chang Kweng Lim, Yasumasa Komoda, Toru Okamoto, Hironobu Miyamoto, Kohji Moriishi, Shintaro Yagi, Arvind H. Patel, Tatsuo Miyamura, Yoshiharu Matsuura

Biochemical and Biophysical Research Communications　Vol. 340　No. 1　p. 200-208　2006/02/03　Research paper (scientific journal)

Nucleolar protein B23 interacts with Japanese encephalitis virus core protein and participates in viral replication

Yoshimi Tsuda, Yoshio Mori, Takayuki Abe, Tetsuo Yamashita, Toru Okamoto, Tohru Ichimura, Kohji Moriishi, Yoshiharu Matsuura

Microbiology and Immunology　Vol. 50　No. 3　p. 225-234　2006　Research paper (scientific journal)

Hepatitis C virus core protein exerts an inhibitory effect on suppressor of cytokine signaling (SOCS)-1 gene expression

Hideyuki Miyoshi, Hajime Fujie, Yoshizumi Shintani, Takeya Tsutsumi, Seiko Shinzawa, Masatoshi Makuuchi, Norihiro Kokudo, Yoshiharu Matsuura, Tetsuro Suzuki, Tatsuo Miyamura, Kyoji Moriya, Kazuhiko Koike

Journal of Hepatology　Vol. 43　No. 5　p. 757-763　2005/11　Research paper (scientific journal)

Essential elements of the capsid protein for self-assembly into empty virus-like particles of hepatitis E virus

Tian Cheng Li, Naokazu Takeda, Tatsuo Miyamura, Yoshiharu Matsuura, Joseph C.Y. Wang, Helena Engvall, Lena Hammar, Li Xing, R. Holland Cheng

Journal of Virology　Vol. 79　No. 20　p. 12999-13006　2005/10　Research paper (scientific journal)

Cell-binding properties of the envelope proteins of porcine endogenous retroviruses

Rie Watanabe, Takayuki Miyazawa, Yoshiharu Matsuura

Microbes and Infection　Vol. 7　No. 4　p. 658-665　2005/04　Research paper (scientific journal)

Molecular determinants for subcellular localization of hepatitis C virus core protein

Ryosuke Suzuki, Shinichiro Sakamoto, Takeya Tsutsumi, Akiko Rikimaru, Keiko Tanaka, Takashi Shimoike, Kohji Moriishi, Takuya Iwasaki, Kiyohisa Mizumoto, Yoshiharu Matsuura, Tatsuo Miyamura, Tetsuro Suzuki

Journal of Virology　Vol. 79　No. 2　p. 1271-1281　2005/01　Research paper (scientific journal)

Identification of basal promoter and enhancer elements in an untranslated region of the TT virus genome

Tetsuro Suzuki, Ryosuke Suzuki, Jin Li, Minako Hijikata, Mami Matsuda, Tiang Cheng Li, Yoshiharu Matsuura, Shunji Mishiro, Tatsuo Miyamura

Journal of Virology　Vol. 78　No. 19　p. 10820-10824　2004/10　Research paper (scientific journal)

Evidence for a polytopic form of the E1 envelope glycoprotein of Hepatitis C virus

Christopher T. Migliaccio, Kathryn E. Follis, Yoshiharu Matsuura, Jack H. Nunberg

Virus Research　Vol. 105　No. 1　p. 47-57　2004/09/15　Research paper (scientific journal)

Development of HCV vaccine

Takayuki Abe, Kohji Moriishi, Yoshiharu Matsuura

Nippon rinsho. Japanese journal of clinical medicine　Vol. 62 Suppl 7　No. Pt 1　p. 139-142　2004/07

Candidate molecules for HCV receptor

Kohji Moriishi, Chang Kwang Limn, Yoshiharu Matsuura

Nippon rinsho. Japanese journal of clinical medicine　Vol. 62 Suppl 7　No. Pt 1　p. 191-194　2004/07

Pseudotype hepatitis C virus enters immature myeloid dendritic cells through the interaction with lectin

Aki Kaimori, Tatsuya Kanto, Chang Kwang Limn, Yasumasa Komoda, Chika Oki, Michiyo Inoue, Hideki Miyatake, Ichiyo Itose, Mitsuru Sakakibara, Takayuki Yakushijin, Tetsuo Takehara, Yoshiharu Matsuura, Norio Hayashi

Virology　Vol. 324　No. 1　p. 74-83　2004/06/20　Research paper (scientific journal)

Expression of influenza neuraminidase in CHO-K1 cells

Takeshi Tanimoto, Yorihiro Nishimura, Yoshiharu Matsuura, Isao Fuke, Toyokazu Ishikawa, Kouichi Yamanishi, Shin ichi Tamura

International Congress Series　Vol. 1263　No. C　p. 568-572　2004/06/01　Research paper (scientific journal)

Production of N-Lauroylated G Protein α-Subunit in Sf9 Insect Cells: The Type of N-Acyl Group of Gα Influences G Protein-Mediated Signal Transduction

Yuichi Hashimoto, Takahiko Matsuda, Yoshiharu Matsuura, Tatsuya Haga, Yoshitaka Fukada

Journal of Biochemistry　Vol. 135　No. 3　p. 319-329　2004/03　Research paper (scientific journal)

Integration of the 5′ end of the retrotransposon, R2Bm, can be complemented by homologous recombination

Hirofumi Fujimoto, Yukiko Hirukawa, Hideki Tani, Yoshiharu Matsuura, Kazuo Hashido, Kozo Tsuchida, Naoko Takada, Masahiko Kobayashi, Hideaki Maekawa

Nucleic Acids Research　Vol. 32　No. 4　p. 1555-1565　2004　Research paper (scientific journal)

Comparison of serum sensitivities of pseudotype retroviruses produced from newly established packaging cell lines of human and feline origins

Rie Watanabe, Takayuki Miyazawa, Yoshiharu Matsuura

Virus Research　Vol. 99　No. 1　p. 89-93　2004/01　Research paper (scientific journal)

Antiapoptotic regulation by hepatitis C virus core protein through up-regulation of inhibitor of caspase-activated DNase

Rodolfo Sacco, Takeya Tsutsumi, Ryosuke Suzuki, Motoyuki Otsuka, Hideki Aizaki, Shinichiro Sakamoto, Mami Matsuda, Naohiko Seki, Yoshiharu Matsuura, Tatsuo Miyamura, Tetsuro Suzuki

Virology　Vol. 317　No. 1　p. 24-35　2003/12/05　Research paper (scientific journal)

Baculovirus vector--gene transfer into mammalian cells

Hideki Tani, Takayuki Abe, Chang Kwang Limn, Rika Mochizuki, Junya Yamagishi, Yoshinori Kitagawa, Rie Watanabe, Kohji Moriishi, Yoshiharu Matsuura

Uirusu. Journal of virology　Vol. 53　No. 2　p. 185-193　2003/12

Sensitivity to human serum of gammaretroviruses produced from pig endothelial cells transduced with glycosyltransferase genes

Takashi Kurihara, Takayuki Miyazawa, Shuji Miyagawa, Keizo Tomonaga, Kenji Hazama, Junko Yamada, Ryota Shirakura, Yoshiharu Matsuura

Xenotransplantation　Vol. 10　No. 6　p. 562-568　2003/11　Research paper (scientific journal)

Mechanisms of hepatitis C virus infection

Kohji Moriishi, Yoshiharu Matsuura

Antiviral Chemistry and Chemotherapy　Vol. 14　No. 6　p. 285-297　2003/11

Hepatitis C virus core protein activates ERK and p38 MAPK in cooperation with ethanol in transgenic mice

Takeya Tsutsumi, Tetsuro Suzuki, Kyoji Moriya, Yoshizumi Shintani, Hajime Fujie, Hideyuki Miyoshi, Yoshiharu Matsuura, Kazuhiko Koike, Tatsuo Miyamura

Hepatology　Vol. 38　No. 4　p. 820-828　2003/10/01　Research paper (scientific journal)

Production and release of infectious hepatitis C virus from human liver cell cultures in the three-dimensional radial-flow bioreactor

Hideki Aizaki, Seishi Nagamori, Mami Matsuda, Hayato Kawakami, Osamu Hashimoto, Hiroaki Ishiko, Masaaki Kawada, Tomokazu Matsuura, Satoshi Hasumura, Yoshiharu Matsuura, Tetsuro Suzuki, Tatsuo Miyamura

Virology　Vol. 314　No. 1　p. 16-25　2003/09/15　Research paper (scientific journal)

Reevaluation of host ranges of feline leukemia virus subgroups

Risa Nakata, Takayuki Miyazawa, Yeon Sil Shin, Rie Watanabe, Takeshi Mikami, Yoshiharu Matsuura

Microbes and Infection　Vol. 5　No. 11　p. 947-950　2003/09　Research paper (scientific journal)

Spontaneous elimination of serum hepatitis C virus (HCV) RNA in chronic HCV carriers: A population-based cohort study

Hisayoshi Watanabe, Takafumi Saito, Haruhide Shinzawa, Kazuo Okumoto, Etsuko Hattori, Tohru Adachi, Tadashi Takeda, Kazuhiko Sugahara, Jun Itsu Ito, Koji Saito, Hitoshi Togashi, Ryosuke Suzuki, Masahiro Hayashi, Tatsuo Miyamura, Yoshiharu Matsuura, Sumio Kawata

Journal of Medical Virology　Vol. 71　No. 1　p. 56-61　2003/09/01　Research paper (scientific journal)

CRMP-2 regulates polarized Numb-mediated endocytosis for axon growth

Takashi Nishimura, Yuko Fukata, Katsuhiro Kato, Tomoya Yamaguchi, Yoshiharu Matsuura, Hiroyuki Kamiguchi, Kozo Kaibuchi

Nature Cell Biology　Vol. 5　No. 9　p. 819-826　2003/09/01　Research paper (scientific journal)

Evaluation of a newly developed immunochromatographic method for detection of norovirus.

Michio Okame, Hainen Yan, Shiho Akihara, Shoko Okitsu, Hideki Tani, Yoshiharu Matsuura, Hiroshi Ushijima

Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases　Vol. 77　No. 8　p. 637-639　2003/08　Research paper (scientific journal)

Baculovirus induces an innate immune response and confers protection from lethal influenza virus infection in mice

Takayuki Abe, Hitoshi Takahashi, Hiroyuki Hamazaki, Naoko Miyano-Kurosaki, Yoshiharu Matsuura, Hiroshi Takaku

Journal of Immunology　Vol. 171　No. 3　p. 1133-1139　2003/08/01　Research paper (scientific journal)

Immunization with recombinant Calmette-Guerin bacillus (BCG)-hepatitis C virus (HCV) elicits HCV-specific cytotoxic T lymphocytes in mice

Satori Uno-Furuta, Kazuhiro Matsuo, Shigenori Tamaki, Shiki Takamura, Akira Kamei, Isao Kuromatsu, Masahiko Kaito, Yoshiharu Matsuura, Tatsuo Miyamura, Yukihiko Adachi, Yasuhiro Yasutomi

Vaccine　Vol. 21　No. 23　p. 3149-3156　2003/07/04　Research paper (scientific journal)

Sumoylation is involved in β-catenin-dependent activation of Tcf-4

Hideki Yamamoto, Motomasa Ihara, Yoshiharu Matsuura, Akira Kikuchi

EMBO Journal　Vol. 22　No. 9　p. 2047-2059　2003/05/01　Research paper (scientific journal)

Usage of myeloma and panning in retrovirus-mediated expression cloning

Masayuki Shimojima, Takayuki Miyazawa, Yumiko Sakurai, Yorihiro Nishimura, Yukinobu Tohya, Yoshiharu Matsuura, Hiroomi Akashi

Analytical Biochemistry　Vol. 315　No. 1　p. 138-140　2003/04　Research paper (scientific journal)

Induction of hepatitis C virus-specific cytotoxic T lymphocytes in mice by immunization with dendritic cells transduced with replication-defective recombinant adenovirus

Masanori Matsui, Osamu Moriya, Nada Abdel-Aziz, Yoshiharu Matsuura, Tatsuo Miyamura, Toshitaka Akatsuka

Vaccine　Vol. 21　No. 3-4　p. 211-220　2002/12/13　Research paper (scientific journal)

Expression profiling of liver cell lines expressing entire or parts of hepatitis C virus open reading frame

Hideki Aizaki, Takashi Harada, Motoyuki Otsuka, Naohiko Seki, Mami Matsuda, Yue Wei Li, Hayato Kawakami, Yoshiharu Matsuura, Tatsuo Miyamura, Tetsuro Suzuki

Hepatology　Vol. 36　No. 6　p. 1431-1438　2002/12/01　Research paper (scientific journal)

Diverging effects of human recombinant anti-hepatitis C virus (HCV) antibody fragments derived from a single patient on the infectivity of a vesicular stomatitis virus/HCV pseudotype

Roberto Burioni, Yoshiharu Matsuura, Nicasio Mancini, Hideki Tani, Tatsuo Miyamura, Pietro E. Varaldo, Massimo Clementi

Journal of Virology　Vol. 76　No. 22　p. 11775-11779　2002/11　Research paper (scientific journal)

Infection of HepG2 cells with recombinant adenovirus encoding the HCV core protein induces p21^WAF1 down-regulation - Effect of transforming growth factor β

Marc Dubourdeau, Tatsuo Miyamura, Yoshiharu Matsuura, Laurent Alric, Bernard Pipy, Denis Rousseau

Journal of Hepatology　Vol. 37　No. 4　p. 486-492　2002/10　Research paper (scientific journal)

Rac1 and Cdc42 capture microtubules through IQGAP1 and CLIP-170

Masaki Fukata, Takashi Watanabe, Jun Noritake, Masato Nakagawa, Masaki Yamaga, Shinya Kuroda, Yoshiharu Matsuura, Akihiro Iwamatsu, Franck Perez, Kozo Kaibuchi

Cell　Vol. 109　No. 7　p. 873-885　2002/06/28　Research paper (scientific journal)

baculovirus systemを用いたSly病遺伝子治療の基礎的検討

小林 博司, 渡部 和彦, 谷 英樹, 松浦 善治, ジェームズ・バースム, 沈 勁松, 大橋 十也, 衛藤 義勝

日本小児科学会雑誌　Vol. 106　No. 2　p. 194-194　2002/02

Alteration of intrahepatic cytokine expression and AP-1 activation in transgenic mice expressing hepatitis C virus core protein

Takeya Tsutsumi, Tetsuro Suzuki, Kyoji Moriya, Hiroshi Yotsuyanagi, Yoshizumi Shintani, Hajime Fujie, Yoshiharu Matsuura, Satoshi Kimura, Kazuhiko Koike, Tatsuo Miyamura

Virology　Vol. 304　No. 2　p. 415-424　2002　Research paper (scientific journal)

Structural analysis of vaccinia virus DIs strain: Application as a new replication-deficient viral vector

Koji Ishii, Yoshiaki Ueda, Kazuhiro Matsuo, Yoshiharu Matsuura, Takashi Kitamura, Kenzo Kato, Yasuyuki Izumi, Kenji Someya, Takeaki Ohsu, Mitsuo Honda, Tatsuo Miyamura

Virology　Vol. 302　No. 2　p. 433-444　2002　Research paper (scientific journal)

Interaction of hepatitis C virus core protein with retinoid X receptor α modulates its transcriptional activity

Takeya Tsutsumi, Tetsuro Suzuki, Takashi Shimoike, Ryosuke Suzuki, Kyoji Moriya, Yoshizumi Shintani, Hajime Fujie, Yoshiharu Matsuura, Kazuhiko Koike, Tatsuo Miyamura

Hepatology　Vol. 35　No. 4　p. 937-946　2002/01/01　Research paper (scientific journal)

Induction of Bad-mediated apoptosis by Sindbis virus infection: Involvement of pro-survival members of the Bcl-2 family

Kohji Moriishi, Minako Koura, Yoshiharu Matsuura

Virology　Vol. 292　No. 2　p. 258-271　2002　Research paper (scientific journal)

Characterization of pseudotype VSV possessing HCV envelope proteins

Yoshiharu Matsuura, Hideki Tani, Kensuke Suzuki, Tomomi Kimura-Someya, Ryosuke Suzuki, Hideki Aizaki, Koji Ishii, Kohji Moriishi, Clinton S. Robison, Michael A. Whitt, Tatsuo Miyamura

Virology　Vol. 286　No. 2　p. 263-275　2001/08/01　Research paper (scientific journal)

Report on 7th International Meeting on Hepatitis C and related viruses, Gold Coast, Australia

H. Aizaki, Y. Matsuura

Uirusu. Journal of virology　Vol. 51　No. 1　p. 109-112　2001/06　Research paper (international conference proceedings)

Characterization of cell-surface determinants important for baculovirus infection

Hideki Tani, Masahiro Nishijima, Hiroshi Ushijima, Tatsuo Miyamura, Yoshiharu Matsuura

Virology　Vol. 279　No. 1　p. 343-353　2001/01/20　Research paper (scientific journal)

Identification of immunodominant hepatitis C virus (HCV)-specific cytotoxic T-cell epitopes by stimulation with endogenously synthesized HCV antigens

Simona Urbani, Jacopo Uggeri, Yoshiharu Matsuura, Tatsuo Miyamura, Amalia Penna, Carolina Boni, Carlo Ferrari

Hepatology　Vol. 33　No. 6　p. 1533-1543　2001　Research paper (scientific journal)

Analysis of the molecules involved in human T-cell leukaemia virus type 1 entry by a vesicular stomatitis virus pseudotype bearing its envelope glycoproteins

K. Okuma, Y. Matsuura, H. Tatsuo, Y. Inagaki, M. Nakamura, N. Yamamoto, Y. Yanagi

Journal of General Virology　Vol. 82　No. 4　p. 821-830　2001　Research paper (scientific journal)

ik3-1/cables is a substrate for cyclin-dependent kinase 3 (cdk 3)

Tadanori Yamochi, Kentaro Semba, Keitaro Tsuji, Kiyohisa Mizumoto, Hiroko Sato, Yoshiharu Matsuura, Ikuo Nishimoto, Masaaki Matsuoka

European Journal of Biochemistry　Vol. 268　No. 23　p. 6076-6082　2001　Research paper (scientific journal)

Erratum: Molecular cloning of a cyclin-like protein associated with cyclin-dependent kinase 3 (cdk 3) in Vivo (Biochemical and Biophysical Research Communications (2000) 273:2 (442-447))

M. Matsuoka, Y. Matsuura, K. Semba, I. Nishimoto

Biochemical and Biophysical Research Communications　Vol. 274　No. 3　2000/08/11　Research paper (scientific journal)

Role of the DExH motif of the Japanese encephalitis virus and hepatitis C virus NS3 proteins in the ATPase and RNA helicase activities

A. Utama, H. Shimizu, F. Hasebe, K. Morita, A. Igarashi, I. Shoji, Y. Matsuura, M. Hatsu, K. Takamizawa, A. Hagiwara, T. Miyamura

Virology　Vol. 273　No. 2　p. 316-324　2000/08/01　Research paper (scientific journal)

Induction of hepatitis C virus-specific cytotoxic T lymphocytes in mice by an intrahepatic inoculation with an expression plasmid

Akira Kamei, Shigenori Tamaki, Hiroyuki Taniyama, Shiki Takamura, Yuki Nishimura, Yumiko Kagawa, Satori Uno-Furuta, Masahiko Kaito, Gisen Kim, Masaaki Toda, Yoshiharu Matsuura, Tatsuo Miyamura, Yukihiko Adachi, Yasuhiro Yasutomi

Virology　Vol. 273　No. 1　p. 120-126　2000/07/20　Research paper (scientific journal)

Molecular cloning of a cyclin-like protein associated with cyclin-dependent kinase 3 (cdk 3) in vivo

Masaaki Matsuoka, Yoshiharu Matsuura, Kentaro Semba, Ikuo Nishimoto

Biochemical and Biophysical Research Communications　Vol. 273　No. 2　p. 442-447　2000/07/05　Research paper (scientific journal)

Phosphorylation of adducin by Rho-kinase plays a crucial role in cell motility

Yuko Fukata, Noriko Oshiro, Nagatoki Kinoshita, Yoji Kawano, Yoichiro Matsuoka, Vann Bennett, Yoshiharu Matsuura, Kozo Kaibuchi

Journal of Cell Biology　Vol. 145　No. 2　p. 347-361　2000/06　Research paper (scientific journal)

Association of membrane-associated guanylate kinase-interacting protein-1 with Raf-1

Ikuko Yao, Toshihisa Ohtsuka, Hiroshi Kawabe, Yoshiharu Matsuura, Yoshimi Takai, Yutaka Hata

Biochemical and Biophysical Research Communications　Vol. 270　No. 2　p. 538-542　2000/04　Research paper (scientific journal)

GSK-3β-dependent phosphorylation of adenomatous polyposis cop gene product can be modulated by β-catenin and protein phosphatase 2A complexed with Axin

Satoshi Ikeda, Michiko Kishida, Yoshiharu Matsuura, Hirofumi Usui, Akira Kikuchi

Oncogene　Vol. 19　No. 4　p. 537-545　2000/01/27　Research paper (scientific journal)

Virus entry is a major determinant of cell tropism of Edmonston and wild-type strains of measles virus as revealed by vesicular stomatitis virus pseudotypes bearing their envelope proteins

Hironobu Tatsuo, Kazu Okuma, Kotaro Tanaka, Nobuyiki Ono, Hiroko Minagawa, Akemi Takade, Yoshiharu Matsuura, Yusuke Yanagi

Journal of Virology　Vol. 74　No. 9　p. 4139-4145　2000　Research paper (scientific journal)

Phosphorylation of ERM proteins at filopodia induced by Cdc42

Nao Nakamura, Noriko Oshiro, Yuko Fukata, Mutsuki Amano, Masaki Fukata, Shinya Kuroda, Yoshiharu Matsuura, Thomas Leung, Louis Lim, Kozo Kaibuchi

Genes to Cells　Vol. 5　No. 7　p. 571-581　2000　Research paper (scientific journal)

cAMP-GEFII is a direct target of cAMP in regulated exocytosis

Nobuaki Ozaki, Tadao Shibasaki, Yasushige Kashima, Takashi Miki, Kazuo Takahashi, Hiroaki Ueno, Yasuhiro Sunaga, Hideki Yano, Yoshiharu Matsuura, Toshihiko Iwanaga, Yoshimi Takai, Susumu Seino

Nature Cell Biology　Vol. 2　No. 11　p. 805-811　2000　Research paper (scientific journal)

Suppression of interferon-induced antiviral activity in cells expressing hepatitis C virus proteins

H. Aizaki, S. Saito, T. Ogino, N. Miyajima, T. Harada, Y. Matsuura, T. Miyamura, M. Kohase

Journal of Interferon and Cytokine Research　Vol. 20　No. 12　p. 1111-1120　2000　Research paper (scientific journal)

Expression of human herpesvirus 6B rep within infected cells and binding of its gene product to the TATA-binding protein in vitro and in vivo

Yasuko Mori, Panadda Dhepakson, Takuya Shimamoto, Keiji Ueda, Yasuyuki Gomi, Hideki Tani, Yoshiharu Matsuura, Koichi Yamanishi

Journal of Virology　Vol. 74　No. 13　p. 6096-6104　2000　Research paper (scientific journal)

Interaction of hepatitis C virus core protein with viral sense RNA and suppression of its translation

Takashi Shimoike, Shigetaka Mimori, Hideki Tani, Yoshiharu Matsuura, Tatsuo Miyamura

Journal of Virology　Vol. 73　No. 12　p. 9718-9725　1999/12　Research paper (scientific journal)

A single immunization with a plasmid encoding hepatitis C virus (HCV) structural proteins under the elongation factor 1-α promoter elicits HCV- specific cytotoxic T-lymphocytes (CTL)

Yuki Nishimura, Akira Kamei, Satori Uno-Furuta, Shigenori Tamaki, Gisen Kim, Yukihiko Adachi, Kagemasa Kuribayashi, Yoshiharu Matsuura, Tatsuo Miyamura, Yasuhiro Yasutomi

Vaccine　Vol. 18　No. 7-8　p. 675-680　1999/11/12　Research paper (scientific journal)

The COOH terminus of Rho-kinase negatively regulates Rho-kinase activity

Mutsuki Amano, Kazuyasu Chihara, Nao Nakamura, Takako Kaneko, Yoshiharu Matsuura, Kozo Kaibuchi

Journal of Biological Chemistry　Vol. 274　No. 45　p. 32418-32424　1999/11/05　Research paper (scientific journal)

Association of frabin with the actin cytoskeleton is essential for microspike formation through activation of Cdc42 small G protein

Masato Umikawa, Hiroshi Obaishi, Hiroyuki Nakanishi, Keiko Satoh-Horikawa, Kenichi Takahashi, Ikuko Hotta, Yoshiharu Matsuura, Yoshimi Takai

Journal of Biological Chemistry　Vol. 274　No. 36　p. 25197-25200　1999/09/03　Research paper (scientific journal)

Identification of the canarypox virus thymidine kinase gene and insertion of foreign genes

Hiroko Amano, Shigeru Morikawa, Hiroyuki Shimizu, Ikuo Shoji, Daisuke Kurosawa, Yoshiharu Matsuura, Tatsuo Miyamura, Yoshiaki Ueda

Virology　Vol. 256　No. 2　p. 280-290　1999/04　Research paper (scientific journal)

Host range of human T-cell leukemia virus type I analyzed by a cell fusion-dependent reporter gene activation assay

Kazu Okuma, Minoru Nakamura, Shuji Nakano, Yoshiyuki Niho, Yoshiharu Matsuura

Virology　Vol. 254　No. 2　p. 235-244　1999/02/15　Research paper (scientific journal)

Internal processing of hepatitis C virus NS3 protein

Ikuo Shoji, Tetsuro Suzuki, Mitsuru Sato, Hideki Aizaki, Tsutomu Chiba, Yoshiharu Matsuura, Tatsuo Miyamura

Virology　Vol. 254　No. 2　p. 315-323　1999/02/15　Research paper (scientific journal)

Plasma membrane recruitment of RalGDS is critical for Ras-dependent Ral activation

Kenji Matsubara, Shosei Kishida, Yoshiharu Matsuura, Hitoshi Kitayama, Makoto Noda, Akira Kikuchi

Oncogene　Vol. 18　No. 6　p. 1303-1312　1999/02/11　Research paper (scientific journal)

In vivo and in vitro phosphorylation of rice dwarf phytoreovirus Pns12 cytoplasmic nonstructural protein

N. Suzuki, D. Hosokawa, Y. Matsuura, A. Kikuchi, T. Omura

Archives of Virology　Vol. 144　No. 7　p. 1371-1380　1999　Research paper (scientific journal)

Steatosis and intrahepatic hepatitis C virus in chronic hepatitis

Hajime Fujie, Hiroshi Yotsuyanagi, Kyoji Moriya, Yoshizumi Shintani, Takeya Tsutsumi, Tadatoshi Takayama, Masatoshi Makuuchi, Yoshiharu Matsuura, Tatsuo Miyamura, Satoshi Kimura, Kazuhiko Koike

Journal of Medical Virology　Vol. 59　No. 2　p. 141-145　1999　Research paper (scientific journal)

Hepatitis C virus core protein binds to apolipoprotein AII and its secretion is modulated by fibrates

Abdelmajid Sabile, Gabriel Perlemuter, Fulvia Bono, Kyoko Kohara, France Demaugre, Michinori Kohara, Yoshiharu Matsuura, Tatsuo Miyamura, Christian Bréchot, Giovanna Barba

Hepatology　Vol. 30　No. 4　p. 1064-1076　1999　Research paper (scientific journal)

characterization of rat mid-pregnancy-specific placental lactogen produced by baculovirus / insect cell expression system

Mitsuko Hirosawa-Takamori, Yoshiharu Matsuura, Satoshi Tanaka, Tomoya Ogawa, Kunio Shiota

Journal of Reproduction and Development　Vol. 45　No. 1　p. 43-50　1999　Research paper (scientific journal)

A human liver cell line exhibits efficient translation of HCV RNAs produced by a recombinant adenovirus expressing T7 RNA polymerase

Yoichiro Aoki, Hideki Aizaki, Takashi Shimoike, Hideki Tani, Koji Ishii, Izumu Saito, Yoshiharu Matsuura, Tatsuo Miyamura

Virology　Vol. 250　No. 1　p. 140-150　1998/10/10　Research paper (scientific journal)

Low stimulatory capacity of lymphoid dendritic cells expressing Hepatitis C virus genes

Yoichi Hiasa, Norio Horiike, S. M.Fazle Akbar, Izumu Saito, Tatsuo Miyamura, Yoshiharu Matsuura, Morikazu Onji

Biochemical and Biophysical Research Communications　Vol. 249　No. 1　p. 90-95　1998/08/10　Research paper (scientific journal)

Role of IQGAP1, a target of the small GTPases Cdc42 and Rac1, in regulation of E-Cadherin-mediated cell-cell adhesion

Shinya Kuroda, Masaki Fukata, Masato Nakagawa, Katsuhiko Fujii, Tomoko Nakamura, Tadashi Ookubo, Ichiro Izawa, Takahiro Nagase, Nobuo Nomura, Hideki Tani, Ikuo Shoji, Yoshiharu Matsuura, Shin Yonehara, Kozo Kaibuchi

Science　Vol. 281　No. 5378　p. 832-835　1998/08/07　Research paper (scientific journal)

Expression of target genes by coinfection with replication-deficient viral vectors

Chan Choo Yap, Koji Ishii, Hideki Aizaki, Hideki Tani, Yoichiro Aoki, Yoshiaki Ueda, Yoshiharu Matsuura, Tatsuo Miyamura

Journal of General Virology　Vol. 79　No. 8　p. 1879-1888　1998/08　Research paper (scientific journal)

Specific isoprenyl group linked to transducin γ-subunit is a determinant of its unique signaling properties among G-proteins

Takahiko Matsuda, Yuichi Hashimoto, Hiroshi Ueda, Tomiko Asano, Yoshiharu Matsuura, Tomoko Doi, Toshifumi Takao, Yasutsugu Shimonishi, Yoshitaka Fukada

Biochemistry　Vol. 37　No. 27　p. 9843-9850　1998/07/07　Research paper (scientific journal)

Critical point mutations for hepatitis C virus NS3 proteinase

Kazunori Yamada, Akiko Mori, Makoto Seki, Junko Kimura, Satoshi Yuasa, Yoshiharu Matsuura, Tatsuo Miyamura

Virology　Vol. 246　No. 1　p. 104-112　1998/06/20　Research paper (scientific journal)

Tomosyn: A syntaxin-1-binding protein that forms a novel complex in the neurotransmitter release process

Yasuyuki Fujita, Hiromichi Shirataki, Toshiaki Sakisaka, Takeshi Asakura, Takeshi Ohya, Hirokazu Kotani, Shigekazu Yokoyama, Hideo Nishioka, Yoshiharu Matsuura, Akira Mizoguchi, Richard H. Scheller, Yoshimi Takai

Neuron　Vol. 20　No. 5　p. 905-915　1998/05　Research paper (scientific journal)

Association of the myosin-binding subunit of myosin phosphatase and moesin: Dual regulation of moesin phosphorylation by Rho-associated kinase and myosin phosphatase

Yuko Fukata, Kazushi Kimura, Noriko Oshiro, Hideyuki Saya, Yoshiharu Matsuura, Kozo Kaibuchi

Journal of Cell Biology　Vol. 141　No. 2　p. 409-418　1998/04　Research paper (scientific journal)

Regulation of the association of adducin with actin filaments by Rho- associated kinase (Rho-kinase) and myosin phosphatase

Kazushi Kimura, Yuko Fukata, Yoichiro Matsuoka, Vann Bennett, Yoshiharu Matsuura, Katsuya Okawa, Akihiro Iwamatsu, Kozo Kaibuchi

Journal of Biological Chemistry　Vol. 273　No. 10　p. 5542-5548　1998/03/06　Research paper (scientific journal)

Interactions of drebrin and gephyrin with profilin

Akiko Mammoto, Takuya Sasaki, Takeshi Asakura, Ikuko Hotta, Hiroshi Imamura, Kazuo Takahashi, Yoshiharu Matsuura, Tomoaki Shirao, Yoshimi Takai

Biochemical and Biophysical Research Communications　Vol. 243　No. 1　p. 86-89　1998/02/04　Research paper (scientific journal)

p140Sra-1 (specifically Rac1-associated protein) is a novel specific target for Rac1 small GTPase

Kenta Kobayashi, Shinya Kuroda, Masaki Fukata, Tomoko Nakamura, Takahiro Nagase, Nobuo Nomura, Yoshiharu Matsuura, Nobuko Yoshida-Kubomura, Akihiro Iwamatsu, Kozo Kaibuchi

Journal of Biological Chemistry　Vol. 273　No. 1　p. 291-295　1998/01/02　Research paper (scientific journal)

High titers of antibodies inhibiting the binding of envelope to human cells correlate with natural resolution of chronic hepatitis C

Koji Ishii, Domenico Rosa, Yushiro Watanabe, Tohru Katayama, Hideharu Harada, Colby Wyatt, Kendo Klyosawa, Hideki Aizaki, Yoshiharu Matsuura, Michael Houghton, Sergio Abrignani, Tatsuo Miyamura

Hepatology　Vol. 28　No. 4 I　p. 1117-1120　1998　Research paper (scientific journal)

Full-length complementary DNA of hepatitis C virus genome from an infectious blood sample

Hldeki Aizaki, Yoichiro Aoki, Takash Harada, Koji Ishii, Tetsuro Suzuki, Seishi Nagamori, Gotaro Toda, Yoshiharu Matsuura, Tatsuo Miyamura

Hepatology　Vol. 27　No. 2　p. 621-627　1998　Research paper (scientific journal)

Neurabin: A novel neural tissue-specific actin filament-binding protein involved in neurite formation

Hiroyuki Nakanishi, Hiroshi Obaishi, Ayako Satoh, Manabu Wada, Kenji Mandai, Keiko Satoh, Hideo Nishioka, Yoshiharu Matsuura, Akira Mizoguchi, Yoshimi Takai

Journal of Cell Biology　Vol. 139　No. 4　p. 951-961　1997/11/17　Research paper (scientific journal)

The Ras target AF-6 interacts with ZO-1 and serves as a peripheral component of tight junctions in epithelial cells

Takaharu Yamamoto, Naozumi Harada, Kyoko Kano, Shin Ichiro Taya, Eli Canaani, Yoshiharu Matsuura, Akira Mizoguchi, Chizuka Ide, Kozo Kaibuchi

Journal of Cell Biology　Vol. 139　No. 3　p. 785-795　1997/11/03　Research paper (scientific journal)

Effects of interferon on the antiviral T-cell response in hepatitis C virus genotype 1b- and genotype 2c-infected patients

Gabriele Missale, Elisabetta Cariani, Vincenzo Lamonaca, Antonella Ravaggi, Angelo Rossini, Roberto Bertoni, Michael Houghton, Yoshiharu Matsuura, Tatsuo Miyamura, Franco Fiaccadori, Carlo Ferrari

Hepatology　Vol. 26　No. 3　p. 792-797　1997/09　Research paper (scientific journal)

Emerging and re-emerging hepatitis viruses

Tatsuo Miyamura, Naokazu Takeda, Yoshiharu Matsuura

FEMS Immunology and Medical Microbiology　Vol. 18　No. 4　p. 307-312　1997/08　Research paper (international conference proceedings)

Hepatitis C virus core protein induces hepatic steatosis in transgenic mice

Kyoji Moriya, Hiroshi Yotsuyanagi, Yoshizumi Shintani, Hajime Fujie, Kotaro Ishibashi, Yoshiharu Matsuura, Tatsuo Miyamura, Kazuhiko Koike

Journal of General Virology　Vol. 78　No. 7　p. 1527-1531　1997/07　Research paper (scientific journal)

Domain-specific phosphorylation of vimentin and glial fibrillary acidic protein by PKN

Kaori Matsuzawa, Hidetaka Kosako, Naoyuki Inagaki, Hideki Shibata, Hideyuki Mukai, Yoshitaka Ono, Mutsuki Amano, Kozo Kaibuchi, Yoshiharu Matsuura, Ichiro Azuma, Masaki Inagaki

Biochemical and Biophysical Research Communications　Vol. 234　No. 3　p. 621-625　1997/05/29　Research paper (scientific journal)

A hybrid baculovirus-T7 RNA polymerase system for recovery of an infectious virus from cDNA

Chan Choo Yap, Koji Ishii, Yoichiro Aoki, Hideki Aizaki, Hideki Tani, Hiroyuki Shimizu, Yoshio Ueno, Tatsuo Miyamura, Yoshiharu Matsuura

Virology　Vol. 231　No. 2　p. 192-200　1997/05/12　Research paper (scientific journal)

Characterization of Ral GDP dissociation stimulator-like (RGL) activities to regulate c-fos promoter and the GDP/GTP exchange of ral

Hiroshi Murai, Masahiro Ikeda, Shosei Kishida, Osamu Ishida, Michiko Okazaki-Kishida, Yoshiharu Matsuura, Akirà Kikuchi

Journal of Biological Chemistry　Vol. 272　No. 16　p. 10483-10490　1997/04　Research paper (scientific journal)

Sensitization to Fas-mediated apoptosis by hepatitis C virus core protein

Anna Ruggieri, Takashi Harada, Yoshiharu Matsuura, Tatsuo Miyamura

Virology　Vol. 229　No. 1　p. 68-76　1997/03/03　Research paper (scientific journal)

Formation of actin stress fibers and focal adhesions enhanced by Rho- kinase

Mutsuki Amano, Kazuyasu Chihara, Kazushi Kimura, Yuko Fukata, Nao Nakamura, Yoshiharu Matsuura, Kozo Kaibuchi

Science　Vol. 275　No. 5304　p. 1308-1311　1997/02/28　Research paper (scientific journal)

Isolation and characterization of a GTPase activating protein specific for the Rab3 subfamily of small G proteins

Koji Fukui, Takuya Sasaki, Katsunori Imazumi, Yoshiharu Matsuura, Hiroyuki Nakanishi, Yoshimi Takai

Journal of Biological Chemistry　Vol. 272　No. 8　p. 4655-4658　1997/02/21　Research paper (scientific journal)

Hepatitis C virus core protein shows a cytoplasmic localization and associates to cellular lipid storage droplets

G. Barba, F. Harper, T. Harada, M. Kohara, S. Goulinet, Y. Matsuura, G. Eder, Zs Schaff, M. J. Chapman, T. Miyamura, C. Bréchot

Proceedings of the National Academy of Sciences of the United States of America　Vol. 94　No. 4　p. 1200-1205　1997/02/18　Research paper (scientific journal)

A polypeptide encoded within the murine AIDS defective virus stimulates primary proliferation of CD8⁺ T-cells

Sung Tae Yee, Eri Abe, Yoshiaki Okada, Yoshiharu Matsuura, Yutaka Takebe, Kazumasa Ogasawara, Hidemi Takahashi, Toshiaki Mizuochi

Immunology Letters　Vol. 55　No. 2　p. 93-98　1997/02　Research paper (scientific journal)

Sialadenitis histologically resembling Sjögren syndrome in mice transgenic for hepatitis C virus envelope genes

Kazuhiko Koike, Kyoji Moriya, Kotaro Ishibashi, Hiroshi Yotsuyanagi, Yoshizumi Shintani, Hajime Fujie, Kiyoshi Kurokawa, Yoshiharu Matsuura, Tatsuo Miyamura

Proceedings of the National Academy of Sciences of the United States of America　Vol. 94　No. 1　p. 233-236　1997/01/07　Research paper (scientific journal)

Detection of antibodies to a recombinant gag protein derived from human endogenous retrovirus clone 4-1 in autoimmune diseases

T. Hishikawa, H. Ogasawara, H. Kaneko, T. Shirasawa, Y. Matsuura, I. Sekigawa, Y. Takasaki, H. Hashimoto, S. Hirose, S. Handa, R. Nagasawa, N. Maruyama

Viral Immunology　Vol. 10　No. 3　p. 137-147　1997　Research paper (scientific journal)

Subcellular localization of hepatitis C virus structural proteins in the liver of transgenic mice

Kyoji Moriya, Hajime Fujie, Hiroshi Yotsuyanagi, Yoshizumi Shintani, Takeya Tsutsumi, Yoshiharu Matsuura, Tatsuo Miyamura, Satoshi Kimura, Kazuhiko Koike

Japanese Journal of Medical Science and Biology　Vol. 50　No. 4-5　p. 169-177　1997　Research paper (scientific journal)

Colocalization of Ras and Ral on the membrane is required for Ras-dependent Ral activation through Ral GDP dissociation stimulator

Shosei Kishida, Shinya Koyama, Kenji Matsubara, Michiko Kishida, Yoshiharu Matsuura, Akira Kikuchi

Oncogene　Vol. 15　No. 24　p. 2899-2907　1997　Research paper (scientific journal)

Molecular cloning and expression of cynomolgus monkey lnterleukin-2 cDNA by the recombinant baculovirus system

Mikiko Yabe, Yoshiharu Matsuura, Masashi Tatsumi

International Archives of Allergy and Immunology　Vol. 113　No. 4　p. 417-423　1997/01/01　Research paper (scientific journal)

Isolation and characterization of a GDP/GTP exchange protein specific for the RAB3 subfamily small G proteins

Manabu Wada, Hiroyuki Nakanishi, Ayako Satoh, Hisanobu Hirano, Hiroshi Obaishi, Yoshiharu Matsuura, Yoshimi Takai

Journal of Biological Chemistry　Vol. 272　No. 7　p. 3875-3878　1997　Research paper (scientific journal)

Efficient gene transfer into various mammalian cells, including non-hepatic cells, by baculovirus vectors

I. Shoji, H. Aizaki, H. Tani, K. Ishii, T. Chiba, I. Saito, T. Miyamura, Y. Matsuura

Journal of General Virology　Vol. 78　No. 10　p. 2657-2664　1997　Research paper (scientific journal)

Mother-to-child transmission of a hepatitis C virus variant with an insertional mutation in its hypervariable region

Hideki Aizaki, Akihiko Saito, Isao Kusakawa, Yoshihisa Ashiwara, Seishi Nagamori, Gotaro Toda, Tetsuro Suzuki, Koji Ishii, Yoshiharu Matsuura, Tatsuo Miyamura

Journal of Hepatology　Vol. 25　No. 5　p. 608-613　1996/11　Research paper (scientific journal)

Polycistronic (tri- or bicistronic) phytoreoviral segments translatable in both plant and insect cells

Nobuhiro Suzuki, Mikiko Sugawara, Donald L. Nuss, Yoshiharu Matsuura

Journal of Virology　Vol. 70　No. 11　p. 8155-8159　1996/11　Research paper (scientific journal)

Intrinsic signaling function of APP as a novel target of three V642 mutations linked to familial Alzheimer's disease

Takashi Okamoto, Shizu Takeda, Ugo Giambarella, Yoshitake Murayama, Takashi Matsui, Toshiaki Katada, Yoshiharu Matsuura, Ikuo Nishimoto

EMBO Journal　Vol. 15　No. 15　p. 3769-3777　1996/08/01　Research paper (scientific journal)

Novel NTP binding property of rice dwarf phytoreovirus minor core protein P5

Nobuhiro Suzuki, Tomonobu Kusano, Yoshiharu Matsuura, Toshihiro Omura

Virology　Vol. 219　No. 2　p. 471-474　1996/05/15　Research paper (scientific journal)

Rom1p and Rom2p are GDP/GTP exchange proteins (GEPs) for the Rho1p small GTP binding protein in Saccharomyces cerevisiae

Kumi Ozaki, Kazuma Tanaka, Hiroshi Imamura, Taro Hihara, Takaaki Kameyama, Hidetaro Nonaka, Hisanobu Hirano, Yoshiharu Matsuura, Yoshimi Takai

EMBO Journal　Vol. 15　No. 9　p. 2196-2207　1996/05/01　Research paper (scientific journal)

Risk factors for hepatitis C virus infection among blood donors in an HIV-epidemic area in Thailand

Pathom Sawanpanyalert, Sumalee Boonmar, Toshiro Maeda, Yoshiharu Matsuura, Tatsuo Miyamura

Journal of Epidemiology and Community Health　Vol. 50　No. 2　p. 174-177　1996/04　Research paper (scientific journal)

Induction of antibodies against structural proteins of hepatitis C virus in mice using recombinant adenovirus

M. Makimura, S. Miyake, N. Akino, K. Takamori, Y. Matsuura, T. Miyamura, I. Saito

Vaccine　Vol. 14　No. 1　p. 28-34　1996/01　Research paper (scientific journal)

Phosphorylation and activation of myosin by Rho-associated kinase (Rho- kinase)

Mutsuki Amano, Masaaki Ito, Kazushi Kimura, Yuko Fukata, Kazuyasu Chihara, Takeshi Nakano, Yoshiharu Matsuura, Kozo Kaibuchi

Journal of Biological Chemistry　Vol. 271　No. 34　p. 20246-20249　1996　Research paper (scientific journal)

Post-translational modifications of Ras and Ral are important for the action of Ral GDP dissociation stimulator

Takao Hinoi, Shosei Kishidat, Shinya Koyama, Masahiro Ikeda, Yoshiharu Matsuura, Akira Kikuchi

Journal of Biological Chemistry　Vol. 271　No. 33　p. 19710-19716　1996　Research paper (scientific journal)

Variations in the hypervariable region 1 of the envelope region E2 of hepatitis C virus RNA appear associated with virus persistence independently of liver disease

M. R. Brunetto, T. Suzuki, H. Aizaky, D. Flichman, P. Colombatto, M. L. Abate, F. Oliveri, Y. Matsuura, F. Bonino, T. Miyamura

Italian Journal of Gastroenterology　Vol. 28　No. 9　p. 499-504　1996　Research paper (scientific journal)

Proteolytic activity of NS3 serine proteinase of hepatitis C virus efficiently expressed in Escherichia coli

Ikuo Shoji, Tetsuro Suzuki, Shinya Chieda, Mitsuru Sato, Takashi Harada, Tsutomu Chiba, Yoshiharu Matsuura, Tatsuo Miyamura

Hepatology　Vol. 22　No. 6　p. 1648-1655　1995/12　Research paper (scientific journal)

Processing of hepatitis C virus envelope proteins

Y. Matsuura, H. Aizaki, K. Ishii, T. Suzuki, T. Miyamura

Nippon rinsho. Japanese journal of clinical medicine　Vol. 53 Suppl　No. Pt 1　p. 51-56　1995/09

Expression of HCV proteins by using recombinant baculoviruses

H. Aizaki, Y. Aoki, M. Sato, K. Ishii, Y. Matsuura, T. Miyamura

Nippon rinsho. Japanese journal of clinical medicine　Vol. 53 Suppl　No. Pt 1　p. 80-84　1995/09

Molecular cloning of a human protein that binds to the retinoblastoma protein and chromosomal mapping

Masafumi Saijo, Yoshihisa Sakai, Tatsuya Kishino, Norio Niikawa, Yoshiharu Matsuura, Kazuhiko Morino, Katsuyuki Tamai, Yoichi Taya

Genomics　Vol. 27　No. 3　p. 511-519　1995/06/10　Research paper (scientific journal)

Hepatitis C virus core region: Helper T cell epitopes recognized by BALB/c and C57BL/6 mice

K. Kakimi, K. Kuribayashi, M. Iwashiro, T. Masuda, M. Sakai, W. Ling, Y. Kubo, H. Kobayashi, K. Higo, M. Seki, Y. Honda, E. Yamada, Y. Matsuura, T. Miyamura, M. Okuma, A. Ishimoto

Journal of General Virology　Vol. 76　No. 5　p. 1205-1214　1995　Research paper (scientific journal)

Genotyping of hepatitis C virus by a simple ELISA method

Hideki Aizaki, Yushiro Watanabe, Takeshi Sarashina, Takato Sakurai, Seishi Nagamori, Tetsuro Suzuki, Yoshiharu Matsuura, Izumu Saito, Tatsuo Miyamura

Clinical and Diagnostic Virology　Vol. 3　No. 1　p. 105-109　1995/01　Research paper (scientific journal)

Expression of hepatitis C virus envelope proteins in transgenic mice

K. Koike, K. Moriya, K. Ishibashi, Y. Matsuura, T. Suzuki, I. Saito, S. Iino, K. Kurokawa, T. Miyamura

Journal of General Virology　Vol. 76　No. 12　p. 3031-3038　1995　Research paper (scientific journal)

Characterization of an established human hepatoma cell line constitutively expressing non-structural proteins of hepatitis C virus by transfection of viral cDNA

T. Harada, D. W. Kim, K. Sagawa, T. Suzuki, K. Takahashi, I. Saito, Y. Matsuura, T. Miyamura

Journal of General Virology　Vol. 76　No. 5　p. 1215-1221　1995　Research paper (scientific journal)

In vivo and in vitro trans-cleavage activity of hepatitis C virus serine proteinase expressed by recombinant baculoviruses

T. Suzuki, M. Sato, S. Chieda, I. Shoji, T. Harada, Y. Yamakawa, S. Watabe, Y. Matsuura, T. Miyamura

Journal of General Virology　Vol. 76　No. 12　p. 3021-3029　1995　Research paper (scientific journal)

Phosphorylation of rabphilin-3A by calmodulin-dependent protein kinase II

Masaki Kato, Takuya Sasaki, Katsunori Imazumi, Kazuo Takahashi, Keishi Araki, Hiromichi Shirataki, Yoshiharu Matsuura, Atsuhiko Ishida, Hitoshi Fujisawa, Yoshimi Takai

Biochemical and Biophysical Research Communications　Vol. 205　No. 3　p. 1776-1784　1994/12/30　Research paper (scientific journal)

Processing of E1 and E2 Glycoproteins of Hepatitis C Virus Expressed in Mammalian and Insect Cells

Yoshiharu Matsuura, Tetsuro Suzuki, Ryosuke Suzuki, Mitsuru Sato, Hideki Aizaki, Izumu Saito, Tatsuo Miyamura

Virology　Vol. 205　No. 1　p. 141-150　1994/11/15　Research paper (scientific journal)

GDP/GTP exchange reaction-stimulating activity of Rabphilin-3A for Rab3A small GTP-binding protein

Yasuyuki Fujita, Takuya Sasaki, Keishi Araki, Kazuo Takahashi, Katsunori Imazumi, Masaki Kato, Yoshiharu Matsuura, Yoshimi Takai

FEBS Letters　Vol. 353　No. 1　p. 67-70　1994/10/10　Research paper (scientific journal)

Characterization of Newcastle disease virus envelope glycoproteins expressed in insect cells

Murakami Yoichi, Kagino Toshihiko, Niikura Masahiro, Mikami Takeshi, Ishii Koji, Matsuura Yoshiharu

Virus Research　Vol. 33　No. 2　p. 123-137　1994/08　Research paper (scientific journal)

Immunodetection of Rice Dwarf Phytoreoviral Proteins in Both Insect and Plant Hosts

Nobuhiro Suzuki, Mikiko Sugawara, Tomonobu Kusano, Hajime Mori, Yoshiharu Matsuura

Virology　Vol. 202　No. 1　p. 41-48　1994/07　Research paper (scientific journal)

Preparation and characterization of human rheumatoid arthritic synovial fluid phospholipase A<inf>2</inf> produced by recombinant baculovirus-infected insect cells

Yasushi Kawauchi, Jun Takasaki, Yoshiharu Matsuura, Yasuhiko Masuho

Journal of Biochemistry　Vol. 116　No. 1　p. 81-87　1994/07　Research paper (scientific journal)

Protective effect of individual glycoproteins of Newcastle disease virus expressed in insect cells: the fusion protein derived from an avirulent strain had lower protective efficacy

Kamiya Naohiro, Niikura Masahiro, Ono Mitsuru, Kai Chieko, Matsuura Yoshiharu, Mikami Takeshi

Virus Research　Vol. 32　No. 3　p. 373-379　1994/06　Research paper (scientific journal)

KIF3A is a new microtubule-based anterograde motor in the nerve axon

Satoru Kondo, Reiko Sato-Yoshitake, Yasuko Noda, Hiroyuki Aizawa, Takao Nakata, Yoshiharu Matsuura, Nobutaka Hirokawa

Journal of Cell Biology　Vol. 125　No. 5　p. 1095-1107　1994/06　Research paper (scientific journal)

Expression and myristoylation of NAP-22 using a baculovirus transfer vector system

Shohei Maekawa, Yoshiharu Matsuura, Shun Nakamura

BBA - Gene Structure and Expression　Vol. 1218　No. 1　p. 119-122　1994/05/17　Research paper (scientific journal)

Erratum: Expression in baculovirus vector system of the nucleocapsid protein gene of rinderpest virus (J. Virol. Meth. 43 (1993) 159-166)

H. Kamata, S. Ohkubo, M. Sugiyama, Y. Matsuura, Y. Kamata, K. Tsukiyama-Kohara, K. Imaoka, C. Kai, Y. Yoshikawa, K. Yamanouchi

Journal of Virological Methods　Vol. 48　No. 2-3　1994　Research paper (scientific journal)

rac p21 is involved in insulin-induced membrane ruffling and rho p21 is involved in hepatocyte growth factor- and 12-O-tetradecanoylphorbol-13- acetate (TPA)-induced membrane ruffling in KB cells

T. Nishiyama, T. Sasaki, K. Takaishi, M. Kato, H. Yaku, K. Araki, Y. Matsuura, Y. Takai

Molecular and Cellular Biology　Vol. 14　No. 4　p. 2447-2456　1994　Research paper (scientific journal)

Characterization of HCV structural proteins expressed in various animal cells

Y. Matsuura, T. Harada, M. Makimura, M. Sato, H. Aizaki, T. Suzuki, T. Miyamura

Intervirology　Vol. 37　No. 2　p. 114-118　1994　Research paper (scientific journal)

The molecular biology of hepatitis C virus

Yoshiharu Matsuura, Tatsuo Miyamura

Seminars in Virology　Vol. 4　No. 5　p. 297-304　1993/10　Research paper (scientific journal)

Expression in baculovirus vector system of the nucleocapsid protein gene of rinderpest virus

H. Kamata, S. Ohkubo, M. Sugiyama, Y. Matsuura, Y. Kamata, K. Tsukiyama-Kohara, K. Imaoka, C. Kai, Y. Yoshikawa, K. Yamanouchi

Journal of Virological Methods　Vol. 43　No. 2　p. 159-165　1993/07　Research paper (scientific journal)

Special issue: Hepatitis C virus. Structural proteins of hepatitis C virus.

Miyamura Tathuo, Suzuki Tethuro, Mathuura Yosiharu

Uirusu　Vol. 43　No. 2　p. 275-283　1993

The post-translational processing of ras p21 is critical for its stimulation of mitogen-activated protein kinase

T. Itoh, K. Kaibuchi, T. Masuda, T. Yamamoto, Y. Matsuura, A. Maeda, K. Shimizu, Y. Takai

Journal of Biological Chemistry　Vol. 268　No. 5　p. 3025-3028　1993　Research paper (scientific journal)

Alzheimer amyloid protein precursor complexes with brain GTP-binding protein G<inf>o</inf>

Ikuo Nishimoto, Takashi Okamoto, Yoshiharu Matsuura, Shuji Takahashi, Toshimi Okamoto, Yoshitake Murayama, Etsuro Ogata

Nature　Vol. 362　No. 6415　p. 75-79　1993　Research paper (scientific journal)

Expression of the Sendai Virus Fusion Protein and the Hemagglutinin-neuraminidase Protein Using a Baculovirus Vector

Toshitsugu Sato, Hideharu Taira, Yoshiharu Matsuura, Kentaro Iwasaki, Teizo Katsumata

Bioscience, Biotechnology and Biochemistry　Vol. 57　No. 4　p. 566-570　1993　Research paper (scientific journal)

A protein factor for ras p21-dependent activation of mitogen-activated protein (MAP) kinase through MAP kinase kinase

T. Itoh, K. Kaibuchi, T. Masuda, T. Yamamoto, Y. Matsuura, A. Maeda, K. Shimizu, Y. Takai

Proceedings of the National Academy of Sciences of the United States of America　Vol. 90　No. 3　p. 975-979　1993　Research paper (scientific journal)

Purification and characterization of a low M<inf>r</inf> GTP-binding protein, ram p25, expressed by baculovirus expression system

Takeshi Suzuki, Koh ichi Nagata, Yoshiharu Matsuura, Yukio Okano, Yoshinori Nozawa

Biochimica et Biophysica Acta (BBA)/Protein Structure and Molecular　Vol. 1159　No. 2　p. 162-168　1992/09/23　Research paper (scientific journal)

Characterization of rabies virus glycoprotein expressed by recombinant baculovirus

Kotaro Tuchiya, Yoshiharu Matsuura, Akihiko Kawai, Akira Ishihama, Susumu Ueda

Virus Research　Vol. 25　No. 1-2　p. 1-13　1992/09/01　Research paper (scientific journal)

Improved serodiagnosis of non‐A, non‐B hepatitis by an assay detecting antibody to hepatitis C virus core antigen

Tohru Katayama, Toshio Mazda, Shu Kikuchi, Shizuko Harada, Yoshiharu Matsuura, Joe Chiba, Hiroyoshi Ohba, Izumu Saito, Tatsuo Miyamura

Hepatology　Vol. 15　No. 3　p. 391-394　1992/03　Research paper (scientific journal)

Site-directed mutagenesis of His-42, His-188 and Lys-263 of human aldose reductase

Takashi Yamaoka, Yoshiharu Matsuura, Kamejiro Yamashita, Tsuyoshi Tanimoto, Chihiro Nishimura

Biochemical and Biophysical Research Communications　Vol. 183　No. 1　p. 327-333　1992/02/28　Research paper (scientific journal)

Expression and characterization of glycoprotein gp35 of hepatitis C virus using recombinant vaccinia virus

M. Kohara, K. Tsukiyama-Kohara, N. Maki, K. Asano, K. Yamaguchi, K. Miki, S. Tanaka, N. Hattori, Y. Matsuura, I. Saito, T. Miyamura, A. Nomoto

Journal of General Virology　Vol. 73　No. 9　p. 2313-2318　1992　Research paper (scientific journal)

Involvement of rho p21 in the GTP-enhanced calcium ion sensitivity of smooth muscle contraction

K. I. Hirata, A. Kikuchi, T. Sasaki, S. Kuroda, K. Kaibuchi, Y. Matsuura, H. Seki, K. Saida, Y. Takai

Journal of Biological Chemistry　Vol. 267　No. 13　p. 8719-8722　1992　Research paper (scientific journal)

The posttranslational processing of ras p21 is critical for its stimulation of yeast adenylate cyclase

H. Horiuchi, K. Kaibuchi, M. Kawamura, Y. Matsuura, N. Suzuki, Y. Kuroda, T. Kataoka, Y. Takai

Molecular and Cellular Biology　Vol. 12　No. 10　p. 4515-4520　1992　Research paper (scientific journal)

Expression of the amino-terminal half of the NS1 region of the hepatitis C virus genome and detection of an antibody to the expressed protein in patients with liver diseases

Y. Inoue, R. Suzuki, Y. Matsuura, S. Harada, J. Chiba, Y. Watanabe, I. Saito, T. Miyamura

Journal of General Virology　Vol. 73　No. 8　p. 2151-2154　1992　Research paper (scientific journal)

Expression of processed envelope protein of hepatitis C virus in mammalian and insect cells

Y. Matsuura, S. Harada, R. Suzuki, Y. Watanabe, Y. Inoue, I. Saito, T. Miyamura

Journal of Virology　Vol. 66　No. 3　p. 1425-1431　1992　Research paper (scientific journal)

Expression of the Marek's disease virus (MDV) homolog of glycoprotein B of herpes simplex virus by a recombinant baculovirus and its identification as the B antigen (gp100, gp60, gp49) of MDV

M. Niikura, Y. Matsuura, D. Endoh, M. Onuma, T. Mikami

Journal of Virology　Vol. 66　No. 5　p. 2631-2638　1992　Research paper (scientific journal)

Post-translational processing of rac p21s is important both for their interaction with the GDP/GTP exchange proteins and for their activation of NADPH oxidase

S. Ando, K. Kaibuchi, T. Sasaki, K. Hiraoka, T. Nishiyama, T. Mizuno, M. Asada, H. Nunoi, I. Matsuda, Y. Matsuura, P. Polakis, F. McCormick, Y. Takai

Journal of Biological Chemistry　Vol. 267　No. 36　p. 25709-25713　1992　Research paper (scientific journal)

High-level secretion of the extracellular domain of the human growth hormone receptor using a baculovirus system

Ota Yoshimi, Asakura Akira, Matsuura Yoshiharu, Kendo Hidemasa, Hitoshio Akio, Iwane Atsuko, Tanaka Toshiki, Kikuchi Masakazu, Ikehara Morio

Gene　Vol. 106　No. 2　p. 159-164　1991/10/15　Research paper (scientific journal)

Purification and characterization of human immunodeficiency virus type 1 nef gene product expressed by a recombinant baculovirus

Yoshiharu Matsuura, Midori Maekawa, Seisuke Hattori, Nobuko Ikegam, Akio Hayashi, Shudo Yamazaki, Chiharu Morita, Yutaka Takebe

Virology　Vol. 184　No. 2　p. 580-586　1991/10　Research paper (scientific journal)

Characterization of haemagglutinin-neuraminidase glycoprotein of Newcastle disease virus expressed by a recombinant baculovirus

Niikura Masahiro, Matsuura Yoshiharu, Hattori Masakazu, Onuma Misao, Mikami Takeshi

Virus Research　Vol. 20　No. 1　p. 31-43　1991/06　Research paper (scientific journal)

Expression and characterization of a rabbit liver cytochrome P450 belonging to P450IIB subfamily with the aid of the baculovirus expression vector system

Daisaku Ohta, Yoshiharu Matsu-ura, Ryo Sato

Biochemical and Biophysical Research Communications　Vol. 175　No. 2　p. 394-399　1991/03/15　Research paper (scientific journal)

Serodiagnosis of hepatitis C virus (HCV) infection with an HCV core protein molecularly expressed by a recombinant baculovirus

J. Chiba, H. Ohba, Y. Matsuura, Y. Watanabe, T. Katayama, S. Kikuchi, I. Saito, T. Miyamura

Proceedings of the National Academy of Sciences of the United States of America　Vol. 88　No. 11　p. 4641-4645　1991　Research paper (scientific journal)

Seroepidemiological Survey of Lymphocytic Choriomeningitis Virus in Wild House Mouse (Mus musculus) in Yokohama Port, Japan

Chiharu Morita, Yoshiharu Matsuura, Eiji Kawashima, Sumio Takahashi, Junji Kawaguchi, Syouzou Iida, Takaaki Yamanaka, Wataru Jitsukawa

Journal of Veterinary Medical Science　Vol. 53　No. 2　p. 219-222　1991　Research paper (scientific journal)

Isolation of Lymphocytic Choriomeningitis Virus from Wild House Mice (Mus musculus) in Osaka Port, Japan

Chiharu Morita, Yoshiharu Matsuura, Hiroki Fujii, Keiichiroh Joh, Kazuhiro Baba, Masayosi Kato, Motoo Hisada

Journal of Veterinary Medical Science　Vol. 53　No. 5　p. 889-892　1991　Research paper (scientific journal)

Expression of the A antigen (gp57-65) of Marek's disease virus by a recombinant baculovirus

M. Niikara, Y. Matsuura, M. Hattori, M. Onuma, T. Mikami

Journal of General Virology　Vol. 72　No. 5　p. 1099-1104　1991　Research paper (scientific journal)

Expression of the S1 sub-unit of pertussis toxin using a recombinant baculovirus.

Y. Matsuura, H. Sato, Y. Sato

Developments in biological standardization　Vol. 73　p. 79-85　1991　Research paper (scientific journal)

cDNA cloning and expression of human aldose reductase

C. Nishimura, Y. Matsuura, T. Tanimoto, T. Yamaoka, T. Akera, T. G. Flynn

Advances in Experimental Medicine and Biology　Vol. 284　p. 119-127　1991　Research paper (international conference proceedings)

A stimulatory GDP/GTP exchange protein for smg p21 is active on the post-translationally processed form of c-Ki-ras p21 and rhoA p21

T. Mizuno, K. Kaibuchi, T. Yamamoto, M. Kawamura, T. Sakoda, H. Fujioka, Y. Matsuura, Y. Takai

Proceedings of the National Academy of Sciences of the United States of America　Vol. 88　No. 15　p. 6442-6446　1991　Research paper (scientific journal)

The posttranslationally modified C-terminal structure of bovine aortic smooth muscle rhoA p21

M. Katayama, M. Kawata, Y. Yoshida, H. Horiuchi, T. Yamamoto, Y. Matsuura, Y. Takai

Journal of Biological Chemistry　Vol. 266　No. 19　p. 12639-12645　1991　Research paper (scientific journal)

An enzyme-linked immunosorbent assay for the measurement of human interleukin-6

Nobuo Ida, Shingou Sakurai, Touko Hosaka, Kazuo Hosoi, Tetsunosuke Kunitomo, Yoshiharu Matsuura, Masayoshi Kohase

Journal of Immunological Methods　Vol. 133　No. 2　p. 279-284　1990/10/19　Research paper (scientific journal)

Identification and nucleotide sequence of the gene encoding a surface antigen induced by vaccinia virus

Yoshiaki Ueda, Shigeru Morikawa, Yoshiharu Matsuura

Virology　Vol. 177　No. 2　p. 588-594　1990/08　Research paper (scientific journal)

Cloning and expression of human aldose reductase

C. Nishimura, Y. Matsuura, Y. Kokai, T. Akera, D. Carper, N. Morjana, C. Lyons, T. G. Flynn

Journal of Biological Chemistry　Vol. 265　No. 17　p. 9788-9792　1990　Research paper (scientific journal)

Analysis of Japanese encephalitis (JE) virus genome and implications for recombinant JE vaccine

K. Yasui, M. Miyamoto, J. Kimura-Kuroda, A. Yasuda, Y. Matsuura, T. Sato, A. Kojima, H. Kubunoya

Southeast Asian Journal of Tropical Medicine and Public Health　Vol. 21　No. 4　p. 663-669　1990　Research paper (international conference proceedings)

Establishment of strongly neutralizing monoclonal antibody to human interleukin-6 and its epitope analysis

Nobuo Ida, Shingou Sakurai, Touko Hosaka, Kazuo Hosoi, Tetsunosuke Kunitomo, Tsuneo Shimazu, Toshihiro Maruyama, Yoshiharu Matsuura, Masayoshi Kohase

Biochemical and Biophysical Research Communications　Vol. 165　No. 2　p. 728-734　1989/12/15　Research paper (scientific journal)

Characterization of Japanese encephalitis virus envelope protein expressed by recombinant baculoviruses

Yoshiharu Matsuura, Michiko Miyamoto, Takanori Sato, Chiharu Morita, Kotaro Yasui

Virology　Vol. 173　No. 2　p. 674-682　1989/12　Research paper (scientific journal)

Expression of IL‐6/IFN‐B<inf>2</inf> in a Baculovirus System and Its Biological Function

YOSHIHARU MATSUURA, MASASHI TATSUMI, KAZUE ENAMI, SHIGERU MORIKAWA, SHUDO YAMAZAKI, MASAYOSHI KOHASE

Annals of the New York Academy of Sciences　Vol. 557　No. 1　p. 122-129　1989/06　Research paper (scientific journal)

Secretion of particles of hepatitis B surface antigen from insect cells using a baculovirus vector.

C. Y. Kang, D. H. Bishop, J. S. Seo, Y. Matsuura, M. Choe

The Journal of general virology　Vol. 68 ( Pt 10)　p. 2607-2613　1987/10　Research paper (scientific journal)

Four serotypes of haemorrhagic fever with renal syndrome viruses identified by polyclonal and monoclonal antibodies

K. Sugiyama, S. Morikawa, Y. Matsuura, E. A. Tkachenko, C. Morita, T. Komatsu, Y. Akao, T. Kitamura

Journal of General Virology　Vol. 68　No. 4　p. 979-987　1987　Research paper (scientific journal)

Baculovirus expression vectors: The requirements for high level expression of proteins, including glycoproteins

Y. Matsuura, R. D. Possee, H. A. Overton, D. H.L. Bishop

Journal of General Virology　Vol. 68　No. 5　p. 1233-1250　1987　Research paper (scientific journal)

Expression of the S-coded genes of lymphocytic choriomeningitis arenavirus using a baculovirus vector

Y. Matsuura, R. D. Possee, D. H.L. Bishop

Journal of General Virology　Vol. 67　No. 8　p. 1515-1529　1986　Research paper (scientific journal)

Analyses of the mRNA transcription processes of Punta Toro phlebovirus (Bunyaviridae)

Takeshi Ihara, Yoshiharu Matsuura, David H.L. Bishop

Virology　Vol. 147　No. 2　p. 317-325　1985/12　Research paper (scientific journal)

Complete sequence of the S RNA of lymphocytic choriomeningitis virus (WE strain) compared to that of pichinde arenavirus

Victor Romanowski, Yoshiharu Matsuura, David H.L. Bishop

Virus Research　Vol. 3　No. 2　p. 101-114　1985/09　Research paper (scientific journal)

Age-dependent transmission of hemorrhagic fever with renal syndrome (HFRS) virus in rats

Ch Morita, Y. Matsuura, Sh Morikawa, T. Kitamura

Archives of Virology　Vol. 85　No. 1-2　p. 145-149　1985/03　Research paper (scientific journal)

Epidemiological study of hemorrhagic fever with renal syndrome related virus infection among urban rats in two islands in Tokyo Bay, Japan

J. Arikawa, I. Takashima, N. Hashimoto, C. Morita, K. Sugiyama, Y. Matsuura, S. Shiga, T. Kitamura

Acta Virologica　Vol. 29　No. 1　p. 66-72　1985　Research paper (scientific journal)

Infectivity titration of hemorrhagic fever with renal syndrome virus: Use of immune adherence hemagglutination for detection of virus growth

Y. Matsuura, K. Sugiyama, C. Morita, S. Morikawa, S. Shiga, T. Komatsu, Y. Akao, T. Kitamura

Journal of Clinical Microbiology　Vol. 20　No. 3　p. 483-485　1984　Research paper (scientific journal)

Determination by immune adherence HA of the antigenic relationship between Rattus- and Apodemus-borne viruses causing hemorrhagic fever with renal syndrome

K. Sugiyama, Y. Matsuura, C. Morita, S. Morikawa, T. Komatsu, S. Shiga, Y. Akao, T. Kitamura

Journal of Infectious Diseases　Vol. 149　No. 3　1984　Research paper (scientific journal)

An immune adherence assay for discrimination between etiologic agents of hemorrhagic fever with renal syndrome

K. Sugiyama, Y. Matsuura, C. Morita, S. Shiga, Y. Akao, T. Komatsu, T. Kitamura

Journal of Infectious Diseases　Vol. 149　No. 1　p. 67-73　1984　Research paper (scientific journal)

Isolation of a virus related to hemorrhagic fever with renal syndrome from urban rats in a nonendemic area

K. Sugiyama, C. Morita, Y. Matsuura, S. Shiga, T. Komatsu, S. Morikawa, T. Kitamura

Journal of Infectious Diseases　Vol. 149　No. 3　1984　Research paper (scientific journal)

Detection of antibody against hemorrhagic fever with renal syndrome (hfrs) virus in sera of house rats captured in port areas of japan

Chiharu Morita, Kazuyoshi Sugiyama, Yoshiharu Matsuura, Toshihiko Komatsu, Takashi Kitamura, Yoriyuki Akao, Wataru Jitsukawa, Hisao Sakakibara

Japanese Journal of Medical Science and Biology　Vol. 36　No. 1　p. 55-57　1983　Research paper (scientific journal)

Location of the iron-sulfur cluster in Spirulina platensis ferredoxin by x-ray analysis

Keizo Ogawa, Tomitake Tsukihara, Hiromasa Tahara, Yukiteru Katsube, Yoshiki Matsu-ura, Nobuo Tanaka, Masao Kakudo, Keishiro Wada, Hiroshi Matsubara

Journal of Biochemistry　Vol. 81　No. 2　p. 529-531　1977/02　Research paper (scientific journal)