顔写真

PHOTO

Hosoi Rie
細井　理恵
Hosoi Rie
細井　理恵
Institutional repository
Graduate School of Medicine　Division of Health Sciences，Assistant Professor

keyword epilepsy，tumor，metabolism，brain function，PET

Institutional repository

Research History 4

  1. 1996 - 2004
    Osaka University　School of Allied Health Sciences, Faculty of Medicine

  2. 2004 -
    - 大阪大学大学院医学系研究科保健学専攻 助手

  3. 1996 -
    - School of Allied Health Sciences, Osaka

  4. University, Faculty of Medicine

Education 2

  1. Osaka University

    - 1996

  2. Osaka University　School of Pharmaceutical Sciences

    - 1994

Professional Memberships 7

  1. 日本分子イメージング学会

  2. 日本脳神経核医学研究会

  3. 日本神経精神薬理学会

  4. 日本核医学会

  5. 日本神経化学会

  6. 日本薬学会

  7. 日本薬理学会

Research Areas 3

  1. Life sciences / Radiology /

  2. Life sciences / Psychiatry /

  3. Life sciences / Pharmaceuticals - health and biochemistry /

Papers 78

  1. Evaluation of intracellular processes in quinolinic acid-induced brain damage by imaging reactive oxygen species generation and mitochondrial complex I activity

    Rie Hosoi, Yuka Fujii, Ohba Hiroyuki, Miho Shukuri, Shingo Nishiyama, Masakatsu Kanazawa, Kenichiro Todoroki, Yasushi Arano, Toshihiro Sakai, Hideo Tsukada, Osamu Inoue

    EJNMMI Research　Vol. 11　No. 1　2021/10　Research paper (scientific journal)

    Publisher: Springer Science and Business Media LLC

  2. A Simple Ex Vivo Semiquantitative Fluorescent Imaging Utilizing Planar Laser Scanner: Detection of Reactive Oxygen Species Generation in Mouse Brain and Kidney

    Rie Hosoi, Sota Sato, Miho Shukuri, Yuka Fujii, Kenichiro Todoroki, Yasushi Arano, Toshihiro Sakai, Osamu Inoue

    Molecular Imaging　Vol. 18　p. 1-7　2019/01　Research paper (scientific journal)

  3. Remarkable increase in (14)C-acetate uptake in an epilepsy model rat brain induced by lithium-pilocarpine

    Rie Hosoi, Daisuke Kitano, Sotaro Momosaki, Kenji Kuse, Antony Gee, Osamu Inoue

    BRAIN RESEARCH　Vol. 1311　p. 158-165　2010/01　Research paper (scientific journal)

  4. Sensitive Reduction in 14C-acetate Uptake in a Short-term Ischemic Rat Brain

    Rie Hosoi, Yuto Kashiwagi, Miwa Tokumura, Kohji Abe, Jun Hatazawa, Osamu Inoue

    Journal of Stroke and Cerebrovascular Diseases　Vol. 16　No. 2　p. 77-81　2007/03　Research paper (scientific journal)

  5. Glial metabolic dysfunction caused neural damage by short-term ischemia in brain

    Rie Hosoi, Yuto Kashiwagi, Jun Hatazawa, Antony Gee, Osamu Inoue

    ANNALS OF NUCLEAR MEDICINE　Vol. 20　No. 5　p. 377-380　2006/06　Research paper (scientific journal)

  6. MicroPET detection of enhanced F-18-FDG utilization by PKA inhibitor in awake rat brain

    R Hosoi, A Matsumura, S Mizokawa, M Tanaka, F Nakamura, K Kobayashi, Y Watanabe, O Inoue

    BRAIN RESEARCH　Vol. 1039　No. 1-2　p. 199-202　2005/03　Research paper (scientific journal)

  7. Effect of astrocytic energy metabolism depressant on C-14-acetate uptake in intact rat brain

    R Hosoi, M Okada, J Hatazawa, A Gee, O Inoue

    JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM　Vol. 24　No. 2　p. 188-190　2004/02　Research paper (scientific journal)

  8. Ex-vivo Imaging of Glial Energy Metabolism in the Neonatal Mouse Brain during Convulsive Seizures with Intranasal Radiotracer Administration.

    Rie Hosoi, Kenya Tada, Takahiro Hayakawa, Yuka Haga

    Molecular imaging and biology　Vol. 27　No. 3　p. 465-473　2025/06　Research paper (scientific journal)

  9. Targeted Imaging of Lung Cancer with Hyperpolarized 129Xe MRI Using Surface-Modified Iron Oxide Nanoparticles as Molecular Contrast Agents.

    Atsuomi Kimura, Seiya Utsumi, Akihiro Shimokawa, Renya Nishimori, Rie Hosoi, Neil J Stewart, Hirohiko Imai, Hideaki Fujiwara

    Cancers　Vol. 14　No. 24　2022/12/09　Research paper (scientific journal)

  10. Ex vivo imaging and analysis of ROS generation correlated with microglial activation in rat model with acute neuroinflammation induced by intrastriatal injection of LPS.

    Miho Shukuri, Miyu Uchino, Takafumi Sakamaki, Satoru Onoe, Rie Hosoi, Kenichiro Todoroki, Yasushi Arano, Toshihiro Sakai, Hiromichi Akizawa, Osamu Inoue

    Biochemical and biophysical research communications　Vol. 584　p. 101-106　2021/12/20　Research paper (scientific journal)

  11. Kinetic study of benzyl [1-14C]acetate as a potential probe for astrocytic energy metabolism in the rat brain: Comparison with benzyl [2-14C]acetate

    Maki Okada, Kazuhiko Yanamoto, Tomohiko Kagawa, Keiko Yoshino, Rie Hosoi, Kohji Abe, Ming-Rong Zhang, Osamu Inoue

    Journal of Cerebral Blood Flow and Metabolism　Vol. 36　No. 2　p. 442-450　2016/02/01　Research paper (scientific journal)

    Publisher: Nature Publishing Group

  12. Improvement of brain uptake for in vivo PET imaging of astrocytic oxidative metabolism using benzyl [1-(11)C]acetate.

    Maki Okada, Ryuji Nakao, Sotaro Momosaki, Kazuhiko Yanamoto, Tatsuya Kikuchi, Toshimitsu Okamura, Hidekatsu Wakizaka, Rie Hosoi, Ming-Rong Zhang, Osamu Inoue

    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine　Vol. 78　p. 102-7　2013/08　Research paper (scientific journal)

  13. Production and purification of the positron emitter zinc-63

    Francisco L. Guerra Gómez, Yuuki Takada, Rie Hosoi, Sotaro Momosaki, Kazuhiko Yanamoto, Kotaro Nagatsu, Hisashi Suzuki, Ming-Rong Zhang, Osamu Inoue, Yasushi Arano, Toshimitsu Fukumura

    Journal of Labelled Compounds and Radiopharmaceuticals　Vol. 55　No. 1　p. 5-9　2012/01　Research paper (scientific journal)

  14. Microdialysis with radiometric monitoring of L-[beta-C-11]DOPA to assess dopaminergic metabolism: effect of inhibitors of L-amino acid decarboxylase, monoamine oxidase, and catechol-O-methyltransferase on rat striatal dialysate

    Maki Okada, Ryuji Nakao, Rie Hosoi, Ming-Rong Zhang, Toshimitsu Fukumura, Kazutoshi Suzuki, Osamu Inoue

    JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM　Vol. 31　No. 1　p. 124-131　2011/01　Research paper (scientific journal)

  15. Remarkable Selectivity of the In Vivo Binding of [H-3]Ro15-4513 to alpha 5 Subtype of Benzodiazepine Receptor in the Living Mouse Brain

    Sotaro Momosaki, Rie Hosoi, Kohji Abe, Osamu Inoue

    SYNAPSE　Vol. 64　No. 12　p. 928-936　2010/12　Research paper (scientific journal)

  16. In vivo imaging and quantitative analysis of TSPO in rat peripheral tissues using small-animal PET with [F-18]FEDAC

    Kazuhiko Yanamoto, Katsushi Kumata, Masayuki Fujinaga, Nobuki Nengaki, Makoto Takei, Hidekatsu Wakizaka, Rie Hosoi, Sotaro Momosaki, Tomoteru Yamasaki, Joji Yui, Kazunori Kawamura, Akiko Hatori, Osamu Inoue, Ming-Rong Zhang

    NUCLEAR MEDICINE AND BIOLOGY　Vol. 37　No. 7　p. 853-860　2010/10　Research paper (scientific journal)

  17. Anticonvulsant effects of methyl ethyl ketone and diethyl ketone in several types of mouse seizure models

    Nobuyoshi Hasebe, Kohji Abe, Eriko Sugiyama, Rie Hosoi, Osamu Inoue

    EUROPEAN JOURNAL OF PHARMACOLOGY　Vol. 642　No. 1-3　p. 66-71　2010/09　Research paper (scientific journal)

  18. PK11195 might selectively suppress the quinolinic acid-induced enhancement of anaerobic glycolysis in glial cells

    Sotaro Momosaki, Natsumi Imamoto, Rie Hosoi, Yoshikazu Sawada, Kohji Abe, Ming-Rong Zhang, Osamu Inoue

    BRAIN RESEARCH　Vol. 1340　p. 18-23　2010/06　Research paper (scientific journal)

  19. Glucose utilization in the brain during acute seizure is a useful biomarker for the evaluation of anticonvulsants: effect of methyl ethyl ketone in lithium-pilocarpine status epilepticus rats

    Akifumi Yamada, Sotaro Momosaki, Rie Hosoi, Kohji Abe, Masatoshi Yamaguchi, Osamu Inoue

    NUCLEAR MEDICINE AND BIOLOGY　Vol. 36　No. 8　p. 949-954　2009/11　Research paper (scientific journal)

  20. Lactate is an alternative energy fuel to glucose in neurons under anesthesia

    Akifumi Yamada, Keisuke Yamamoto, Natsumi Imamoto, Sotaro Momosaki, Rie Hosoi, Masatoshi Yamaguchi, Osamu Inoue

    NEUROREPORT　Vol. 20　No. 17　p. 1538-1542　2009/11　Research paper (scientific journal)

  21. In vivo monitoring of extracellular N-13-glutamine derived from blood-borne N-13-ammonia in rat striatum using microdialysis with radio-LC method

    Maki Okada, Ryuji Nakao, Rie Hosoi, Ming-Rong Zhang, Toshimitsu Fukumura, Kazutoshi Suzuki, Osamu Inoue

    JOURNAL OF NEUROSCIENCE METHODS　Vol. 184　No. 1　p. 37-41　2009/10　Research paper (scientific journal)

  22. Methyl ethyl ketone blocks status epilepticus induced by lithium-pilocarpine in rats

    Osamu Inoue, Eriko Sugiyama, Nobuyoshi Hasebe, Noriko Tsuchiya, Rie Hosoi, Masatoshi Yamaguchi, Kohji Abe, Antony Gee

    BRITISH JOURNAL OF PHARMACOLOGY　Vol. 158　No. 3　p. 872-878　2009/10　Research paper (scientific journal)

  23. グリア代謝抑制が99ｍＴｃ－ＨＭＰＡＯのラット脳内の滞留に及ぼす影響

    佐藤千文, 網谷美里, 今本奈津美, 山田明史, 桃崎壮太郎, 細井理恵, 井上修

    Radioisotopes　2009/10　Research paper (scientific journal)

  24. Inhibitory effect of methyl ethyl ketone upon the enhancement of cerebral blood flow during status epilepticus induced by lithium-pilocarpine

    Eriko Sugiyama, Yuina Matsuki, Sotaro Momosakia, Rie Hosoi, Nobuyoshi Hasebe, Kohji Abe, Osamu Inoue

    NEUROSCIENCE LETTERS　Vol. 462　No. 3　p. 300-302　2009/09　Research paper (scientific journal)

  25. De-coupling of blood flow and metabolism in the rat brain induced by glutamate

    Shinichiro Hirose, Sotaro Momosaki, Kazunari Sasaki, Rie Hosoi, Kohji Abe, Antony Gee, Osamu Inoue

    ANNALS OF NUCLEAR MEDICINE　Vol. 23　No. 3　p. 293-300　2009/05　Research paper (scientific journal)

  26. Uncoupling of flow and metabolism by chloral hydrate: a rat in-vivo autoradiographic study

    Miki Uematsu, Masashi Takasawa, Rie Hosoi, Osamu Inoue

    NEUROREPORT　Vol. 20　No. 3　p. 219-222　2009/02　Research paper (scientific journal)

  27. Role of NMDA receptor upon [C-14]acetate uptake into intact rat brain

    Shinichiro Hirose, Sotaro Momosaki, Rie Hosoi, Kohji Abe, Antony Gee, Osamu Inoue

    ANNALS OF NUCLEAR MEDICINE　Vol. 23　No. 2　p. 143-147　2009/02　Research paper (scientific journal)

  28. PET-MRI同時計測による生体の形態及び機能イメージング

    細井理恵

    ファルマシア　Vol. 45　No. 2　p. 174-175　2009/02

    Publisher: 公益社団法人日本薬学会

  29. Characterization of C-14-acetate uptake in cultured rat astrocytes

    Rie Hosoi, Yasuyo Matsuyama, Shin-ichiro Hirose, Yutaka Koyama, Toshio Matsuda, Antony Gee, Osamu Inoue

    BRAIN RESEARCH　Vol. 1253　p. 69-73　2009/02　Research paper (scientific journal)

  30. 脳卒中のイメージング マクロからミクロまで 神経細胞のイメージング、グリア細胞のイメージング

    畑澤 順, 下瀬川 恵久, 今泉 昌男, 高沢 正志, 木村 泰之, 梶本 勝文, 加藤 弘樹, 田中 真希子, 井上 修, 細井 理恵

    脳卒中　Vol. 29　No. 6　p. 832-832　2007/11

    Publisher: (一社)日本脳卒中学会

  31. [C-14]Benzyl acetate is a potential radiotracer for the measurement of glial metabolism in the rat brain

    Sotaro Momosaki, Rie Hosoi, Tomoya Sanuki, Kenichiro Todoroki, Masatoshi Yamaguchi, Antony Gee, Osamu Inoue

    NUCLEAR MEDICINE AND BIOLOGY　Vol. 34　No. 8　p. 939-944　2007/11　Research paper (scientific journal)

  32. Role of NMDA receptors in the increase of glucose metabolism in the rat brain induced by fluorocitrate

    Shinichiro Hirose, Yukiko Umetani, Misato Amitani, Rie Hosol, Sotaro Momosaki, Jun Hatazawa, Antony Gee, Osamu Inoue

    NEUROSCIENCE LETTERS　Vol. 415　No. 3　p. 259-263　2007/03　Research paper (scientific journal)

  33. Evaluation of [C-14]phenylacetate as a prototype tracer for the measurement of glial metabolism in the rat brain

    Osamu Inoue, Rie Hosoi, Sotaro Momosaki, Keisuke Yamamoto, Misato Amitani, Masatoshi Yamaguchi, Antony Gee

    NUCLEAR MEDICINE AND BIOLOGY　Vol. 33　No. 8　p. 985-989　2006/11　Research paper (scientific journal)

  34. Blood flow dependence of the intratumoral distribution of peripheral benzodiazepine receptor binding in intact mouse fibrosarcoma

    Misato Amitani, Ming-Rong Zhang, Junko Noguchi, Katsushi Kumata, Takeh Ito ito, Nobuhiko Takai, Kazutoshi Suzuki, Rie Hosoi, Osamu Inoue

    NUCLEAR MEDICINE AND BIOLOGY　Vol. 33　No. 8　p. 971-975　2006/11　Research paper (scientific journal)

  35. The apparent positive cooperativity of in vivo [H-3]PK-11195 binding in mouse fibrosarcoma

    Sotaro Momosaki, Rie Hosoi, Nobuhiko Takai, Antony Gee, Osamu Inoue

    NUCLEAR MEDICINE AND BIOLOGY　Vol. 33　No. 6　p. 797-800　2006/08　Research paper (scientific journal)

  36. FDG-PETによる炎症組織の診断のための基礎的検討

    細井理恵

    INNERVISION　Vol. 7　p. 23-23　2006/07

  37. PETによるグリア細胞の機能イメージングの試み

    網谷美里, 桃崎壮太郎, 細井理恵, 井上修

    PET通信　Vol. 55　p. 6-8　2006/06

  38. 11C‐酢酸PETによる脳グリア細胞のエネルギー代謝イメージング

    梶本勝文, 奥直彦, 長谷川新治, 木村泰之, 田中真希子, 加藤弘樹, 金井泰和, 細井理恵, 井上修, 北川一夫, 堀正二, 畑澤順

    脳循環代謝　Vol. 18　No. 1　2006/04/30

  39. comparative measurement of in vivo and vitro receptor binding in the same rat brain

    Vol. 55　No. 1　p. 29-33　2006/01　Research paper (scientific journal)

  40. assessment of the metabolic trapping rate of FDG in rat brain using dual tracer autoradiography with 18F-FDG and 14C-FDG

    AMITANI Misato, MOMOSAKI Sotaro, TAGUCHI Hitomi, HOSOI Rie, HATAZAWA Jun, INOUE Osamu

    Radioisotopes　Vol. 54　No. 12　p. 587-592　2005/12

    Publisher:

  41. Distinct different intra-tumor distribution of FDG between early phase and late phase in mouse fibrosarcoma

    O Inoue, M Shukuri, R Hosoi, M Amitani, N Matsuura, J Hatazawa, N Takai

    ANNALS OF NUCLEAR MEDICINE　Vol. 19　No. 8　p. 655-659　2005/12　Research paper (scientific journal)

  42. Changes in in vivo [H-3]-Ro15-4513 binding induced by forced swimming in mice

    M Amitani, Y Umetani, R Hosoi, K Kobayashi, K Abe, O Inoue

    SYNAPSE　Vol. 58　No. 1　p. 23-29　2005/10　Research paper (scientific journal)

  43. Effect of rolipram on relative C-14-deoxyglucose uptake in inflammatory lesions and skeletal muscle

    M Shukuri, M Terai, R Hosoi, T Nishimura, A Gee, O Inoue

    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING　Vol. 32　No. 2　p. 163-166　2005/02　Research paper (scientific journal)

  44. Rat-PET study without anesthesia: Anesthetics modify the dopamine D-1 receptor binding in rat brain

    S Momosaki, K Hatano, Y Kawasumi, T Kato, R Hosoi, K Kobayashi, O Inoue, K Ito

    SYNAPSE　Vol. 54　No. 4　p. 207-213　2004/12　Research paper (scientific journal)

  45. Discrepancy between cell injury and benzodiazepine receptor binding after transient middle cerebral artery occlusion in rats

    K Abe, Y Kashiwagi, M Tokumura, R Hosoi, J Hatazawa, O Inoue

    SYNAPSE　Vol. 53　No. 4　p. 234-239　2004/09　Research paper (scientific journal)

  46. Uncoupling of flow and metabolism induced by sodium nitroprusside in rat cerebral cortex

    O Inoue, H Taguchi, T Watanabe, R Hosoi, K Kobayashi, T Nishimura, A Gee

    NEUROREPORT　Vol. 15　No. 1　p. 141-145　2004/01　Research paper (scientific journal)

  47. Intrastriatal microinjection of sodium nitroprusside induces cell death and reduces binding of dopaminergic receptors

    K Yanamoto, R Hosoi, Y Uesaka, K Abe, H Tsukada, O Inoue

    SYNAPSE　Vol. 50　No. 2　p. 137-143　2003/11　Research paper (scientific journal)

  48. Ionic interaction of [C-11]-N, alpha-dimethylbenzylamine (DMBA) in rodent brain

    O Inoue, R Hosoi, S Momosaki, K Kobayashi, T Kida, K Suzuki, A Gee

    ANNALS OF NUCLEAR MEDICINE　Vol. 17　No. 6　p. 469-473　2003/09　Research paper (scientific journal)

  49. Sensitivities of benzodiazepine receptor binding and muscarinic acetylcholine receptor binding for the detection of neural cell death caused by sodium nitroprusside microinjection in rat brain

    Inoue O, Yanamoto K, Fujiwara Y, Hosoi R, Kobayashi K, Tsukada H

    Synapse. 2003 Aug;49(2):134-41.　2003/05　Research paper (scientific journal)

  50. Effect of rolipram on muscarinic acetylcholine receptor binding in the intact mouse brain

    R Hosoi, M Ishikawa, K Kobayashi, A Gee, M Yamaguchi, O Inoue

    JOURNAL OF NEURAL TRANSMISSION　Vol. 110　No. 4　p. 363-372　2003/04　Research paper (scientific journal)

  51. Effect of sabcomeline on muscarinic and dopamine receptor binding in intact mouse brain

    R Hosoi, K Kobayashi, J Ishida, M Yamaguchi, O Inoue

    ANNALS OF NUCLEAR MEDICINE　Vol. 17　No. 2　p. 123-130　2003/04　Research paper (scientific journal)

  52. 下肢腫ようの糖代謝およびDNA合成能におよぼす炭素線局所照射の影響-ダブルトレーサー法による早期腫よう増殖能の判定-

    高井伸彦, 井上修, 細井理恵, 小池幸子, 安藤興一, 鵜沢玲子, 扶川武志, 物部真奈美

    日本医学放射線学会雑誌　Vol. 63　No. 5　2003

  53. Enhancement of the relative uptake of F-18-FDG in mouse fibrosarcoma by rolipram

    K Kobayashi, R Hosoi, S Momosaki, S Koike, K Ando, T Nishimura, O Inoue

    ANNALS OF NUCLEAR MEDICINE　Vol. 16　No. 7　p. 507-510　2002/11　Research paper (scientific journal)

  54. Increment of in vivo binding of [H-3]SCH 23390, a dopamine D-1 receptor ligand, induced by cyclic AMP-dependent protein kinase in rat brain

    K Abe, R Hosoi, S Momosaki, K Kobayashi, N Ibii, O Inoue

    BRAIN RESEARCH　Vol. 952　No. 2　p. 211-217　2002/10　Research paper (scientific journal)

  55. Rolipram depresses [H-3]2-deoxyglucose uptake in mouse brain and heart in vivo

    M Ishikawa, R Hosoi, K Kobayashi, T Nishimura, O Inoue

    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING　Vol. 29　No. 9　p. 1212-1215　2002/09　Research paper (scientific journal)

  56. Effects of rolipram on in vivo dopamine receptor binding

    R Hosoi, M Ishikawa, K Kobayashi, A Gee, M Yamaguchi, O Inoue

    JOURNAL OF NEURAL TRANSMISSION　Vol. 109　No. 9　p. 1139-1149　2002/09　Research paper (scientific journal)

  57. Changes in histological construction and decrease in H-3-QNB binding in the rat brain after prenatal X-irradiation

    S Momosaki, XZ Sun, N Takai, R Hosoi, O Inoue, S Takahashi

    JOURNAL OF RADIATION RESEARCH　Vol. 43　No. 3　p. 277-282　2002/09　Research paper (scientific journal)

  58. 脳・心筋の糖代謝に対するcAMPの役割

    細井 理恵, 桃崎 荘太郎, 石川 恵, 阿部 浩司, 伊比井 信廣, 井上 修

    日本神経精神薬理学雑誌 = Japanese journal of psychopharmacology　Vol. 21　No. 6　p. 291-291　2001/12/25

  59. リガンド-受容体結合に及ぼすcAMPの影響に関する検討

    桃崎壮太郎, 柳本和彦, 細井理恵, 阿部浩司, 伊比井信広, 井上修

    日本神経精神薬理学雑誌　Vol. 21　No. 6　p. 292-292　2001/12

  60. The role of the cAMP-PKA system in the short-term regulation of striatal [C-14]-2-deoxyglucose uptake in freely moving rats

    R Hosoi, S Momosaki, N Ibii, K Abe, T Itoh, O Inoue

    BRAIN RESEARCH　Vol. 921　No. 1-2　p. 260-263　2001/12　Research paper (scientific journal)

  61. Different sensitivities to competitive inhibition of benzodiazepine receptor binding of C-11-iomazenil and C-11-flumazenil in rhesus monkey brain

    O Inoue, R Hosoi, K Kobayashi, T Itoh, A Gee, K Suzuki

    ANNALS OF NUCLEAR MEDICINE　Vol. 15　No. 2　p. 137-139　2001/04　Research paper (scientific journal)

  62. Studies on radiatioin induced brain dysfunction

    2000/04　Research paper (bulletin of university, research institution)

    Publisher:

  63. Radiochemmical Analysis of Auto-activated 11C-Products and Study on the Mechanism for Accumulation of 11C-Methionine

    2000/04　Research paper (bulletin of university, research institution)

    Publisher:

  64. PET、SPECT を用いた脳内レセプター.酵素と薬物の相互作用研究

    井上修, 細井理恵

    月刊薬事　Vol. 142　No. 4　p. 1221-1226　2000/03　Research paper (scientific journal)

    Publisher: 医薬品適正使用のための臨床薬物動態 月刊薬事2000年3月臨時増刊号

  65. Mapping of Neural cell and glia cell activity with PET

    1999/04　Research paper (bulletin of university, research institution)

    Publisher:

  66. Studies on radiation induced brain dysfunction

    1999/04　Research paper (bulletin of university, research institution)

    Publisher:

  67. Discrepancies in apparent dopamine D2 receptor occupancy between H-3-raclopride and H-3-N-methylspiperone

    O Inoue, K Kobayashi, R Hosoi, M Yamaguchi, A Gee

    JOURNAL OF NEURAL TRANSMISSION　Vol. 106　No. 11-12　p. 1099-1104　1999　Research paper (scientific journal)

  68. Discrepancy of benzodiazepine receptor occupancy between H-3-flumazenil and I-125-iomazenil in intact mouse brain

    R Hosoi, K Kobayashi, Y Watanabe, O Inoue

    JOURNAL OF NEURAL TRANSMISSION　Vol. 106　No. 3-4　p. 243-256　1999　Research paper (scientific journal)

  69. Evaluation of in vivo binding properties of H-3-NMPB and H-3-QNB in mouse brain

    R Hosoi, K Kobayashi, Y Watanabe, O Inoue

    JOURNAL OF NEURAL TRANSMISSION　Vol. 106　No. 7-8　p. 583-592　1999　Research paper (scientific journal)

  70. Opposing effects of clomipramine on [125I]RTI-55 and [3H]N-methylspiperone binding in mouse striatum: important role of other factors than endogenous dopamine?

    Inoue O, Kobayashi K, Hosoi R

    Synapse　1998/04　Research paper (scientific journal)

    Publisher:

  71. Changes in apparent in vivo binding of [┣D13┫D1H]Changes in apparent in vivo binding of [3H]raclopride and [3H]N-methylspiperone induced by oxotremorine

    Kobayashi K, Gee A, Hosoi R, Inoue O

    1998/04　Research paper (scientific journal)

  72. Mapping of neural cell and glia cell activity with PET

    1998/04　Research paper (bulletin of university, research institution)

    Publisher:

  73. Studies on radiation induced brain dysfunction

    1998/04　Research paper (bulletin of university, research institution)

    Publisher:

  74. Effects of the GABAergic system on in vivo binding of [H-3]N-methylspiperone

    T Nakano, K Kobayashi, R Hosoi, S Wakahara, Y Watanabe, T Nishimura, O Inoue

    NEUROPHARMACOLOGY　Vol. 37　No. 3　p. 375-381　1998　Research paper (scientific journal)

  75. Isoform-specific up-regulation by ouabain of Na+,K+-ATPase in cultured rat astrocytes.

    Hosoi R, Matsuda T, Asano S, Nakamura H, Hashimoto H, Takuma K, Baba A

    J Neurochem　Vol. 69　No. 5　p. 2189-2196　1997/04　Research paper (scientific journal)

  76. Ouabain-induced cell proliferation in cultured rat astrocytes

    Y Murata, T Matsuda, K Tamada, R Hosoi, S Asano, K Takuma, K Tanaka, A Baba

    JAPANESE JOURNAL OF PHARMACOLOGY　Vol. 72　No. 4　p. 347-353　1996/12　Research paper (scientific journal)

  77. Involvement of Na+,K+-ATPase in the mitogenic effect of insulin-like growth factor-I on cultured rat astrocytes

    T Matsuda, Y Murata, K Tanaka, R Hosoi, M Hayashi, K Tamada, K Takuma, A Baba

    JOURNAL OF NEUROCHEMISTRY　Vol. 66　No. 2　p. 511-516　1996/02　Research paper (scientific journal)

  78. ウアバインによる培養アストロサイトNa,K-ATPaseアイソフォームα1,β1の選択的誘導

    神経化学　Vol. 35　No. 3　1996

Misc. 74

  1. Microdialysis with radiometric monitoring of L-[beta-C-11]DOPA to assess dopaminergic metabolism: effect of inhibitors of L-amino acid decarboxylase, monoamine oxidase, and catechol-O-methyltransferase on rat striatal dialysate

    Maki Okada, Ryuji Nakao, Rie Hosoi, Ming-Rong Zhang, Toshimitsu Fukumura, Kazutoshi Suzuki, Osamu Inoue

    JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM　Vol. 31　No. 1　p. 124-131　2011/01

  2. Remarkable Selectivity of the In Vivo Binding of [H-3]Ro15-4513 to alpha 5 Subtype of Benzodiazepine Receptor in the Living Mouse Brain

    Sotaro Momosaki, Rie Hosoi, Kohji Abe, Osamu Inoue

    SYNAPSE　Vol. 64　No. 12　p. 928-936　2010/12

  3. In vivo imaging and quantitative analysis of TSPO in rat peripheral tissues using small-animal PET with [F-18]FEDAC

    Kazuhiko Yanamoto, Katsushi Kumata, Masayuki Fujinaga, Nobuki Nengaki, Makoto Takei, Hidekatsu Wakizaka, Rie Hosoi, Sotaro Momosaki, Tomoteru Yamasaki, Joji Yui, Kazunori Kawamura, Akiko Hatori, Osamu Inoue, Ming-Rong Zhang

    NUCLEAR MEDICINE AND BIOLOGY　Vol. 37　No. 7　p. 853-860　2010/10

  4. Anticonvulsant effects of methyl ethyl ketone and diethyl ketone in several types of mouse seizure models

    Nobuyoshi Hasebe, Kohji Abe, Eriko Sugiyama, Rie Hosoi, Osamu Inoue

    EUROPEAN JOURNAL OF PHARMACOLOGY　Vol. 642　No. 1-3　p. 66-71　2010/09

  5. PK11195 might selectively suppress the quinolinic acid-induced enhancement of anaerobic glycolysis in glial cells

    Sotaro Momosaki, Natsumi Imamoto, Rie Hosoi, Yoshikazu Sawada, Kohji Abe, Ming-Rong Zhang, Osamu Inoue

    BRAIN RESEARCH　Vol. 1340　p. 18-23　2010/06

  6. Lactate is an alternative energy fuel to glucose in neurons under anesthesia

    Akifumi Yamada, Keisuke Yamamoto, Natsumi Imamoto, Sotaro Momosaki, Rie Hosoi, Masatoshi Yamaguchi, Osamu Inoue

    NEUROREPORT　Vol. 20　No. 17　p. 1538-1542　2009/11

  7. Glucose utilization in the brain during acute seizure is a useful biomarker for the evaluation of anticonvulsants: effect of methyl ethyl ketone in lithium-pilocarpine status epilepticus rats

    Akifumi Yamada, Sotaro Momosaki, Rie Hosoi, Kohji Abe, Masatoshi Yamaguchi, Osamu Inoue

    NUCLEAR MEDICINE AND BIOLOGY　Vol. 36　No. 8　p. 949-954　2009/11

  8. Methyl ethyl ketone blocks status epilepticus induced by lithium-pilocarpine in rats

    Osamu Inoue, Eriko Sugiyama, Nobuyoshi Hasebe, Noriko Tsuchiya, Rie Hosoi, Masatoshi Yamaguchi, Kohji Abe, Antony Gee

    BRITISH JOURNAL OF PHARMACOLOGY　Vol. 158　No. 3　p. 872-878　2009/10

  9. In vivo monitoring of extracellular N-13-glutamine derived from blood-borne N-13-ammonia in rat striatum using microdialysis with radio-LC method

    Maki Okada, Ryuji Nakao, Rie Hosoi, Ming-Rong Zhang, Toshimitsu Fukumura, Kazutoshi Suzuki, Osamu Inoue

    JOURNAL OF NEUROSCIENCE METHODS　Vol. 184　No. 1　p. 37-41　2009/10

  10. Inhibitory effect of methyl ethyl ketone upon the enhancement of cerebral blood flow during status epilepticus induced by lithium-pilocarpine

    Eriko Sugiyama, Yuina Matsuki, Sotaro Momosakia, Rie Hosoi, Nobuyoshi Hasebe, Kohji Abe, Osamu Inoue

    NEUROSCIENCE LETTERS　Vol. 462　No. 3　p. 300-302　2009/09

  11. De-coupling of blood flow and metabolism in the rat brain induced by glutamate

    Shinichiro Hirose, Sotaro Momosaki, Kazunari Sasaki, Rie Hosoi, Kohji Abe, Antony Gee, Osamu Inoue

    ANNALS OF NUCLEAR MEDICINE　Vol. 23　No. 3　p. 293-300　2009/05

  12. Uncoupling of flow and metabolism by chloral hydrate: a rat in-vivo autoradiographic study

    Miki Uematsu, Masashi Takasawa, Rie Hosoi, Osamu Inoue

    NEUROREPORT　Vol. 20　No. 3　p. 219-222　2009/02

  13. Role of NMDA receptor upon [C-14]acetate uptake into intact rat brain

    Shinichiro Hirose, Sotaro Momosaki, Rie Hosoi, Kohji Abe, Antony Gee, Osamu Inoue

    ANNALS OF NUCLEAR MEDICINE　Vol. 23　No. 2　p. 143-147　2009/02

  14. Characterization of C-14-acetate uptake in cultured rat astrocytes

    Rie Hosoi, Yasuyo Matsuyama, Shin-ichiro Hirose, Yutaka Koyama, Toshio Matsuda, Antony Gee, Osamu Inoue

    BRAIN RESEARCH　Vol. 1253　p. 69-73　2009/02

  15. グリア代謝抑制が99ｍＴｃ－ＨＭＰＡＯのラット脳内の滞留に及ぼす影響

    Radioisotopes　Vol. 2009;58(10):649-654　2009

  16. [C-14]Benzyl acetate is a potential radiotracer for the measurement of glial metabolism in the rat brain

    Sotaro Momosaki, Rie Hosoi, Tomoya Sanuki, Kenichiro Todoroki, Masatoshi Yamaguchi, Antony Gee, Osamu Inoue

    NUCLEAR MEDICINE AND BIOLOGY　Vol. 34　No. 8　p. 939-944　2007/11

  17. 脳卒中のイメージング:マクロからミクロまで 神経細胞のイメージング、グリア細胞のイメージング

    畑澤 順, 下瀬川 恵久, 今泉 昌男, 高沢 正志, 木村 泰之, 梶本 勝文, 加藤 弘樹, 田中 真希子, 井上 修, 細井 理恵

    脳卒中　Vol. 29　No. 2　p. 205-205　2007/03

    Publisher: (一社)日本脳卒中学会

  18. Sensitive Reduction in 14C-acetate Uptake in a Short-term Ischemic Rat Brain

    Rie Hosoi, Yuto Kashiwagi, Miwa Tokumura, Kohji Abe, Jun Hatazawa, Osamu Inoue

    Journal of Stroke and Cerebrovascular Diseases　Vol. 16　No. 2　p. 77-81　2007/03

  19. Role of NMDA receptors in the increase of glucose metabolism in the rat brain induced by fluorocitrate

    Shinichiro Hirose, Yukiko Umetani, Misato Amitani, Rie Hosol, Sotaro Momosaki, Jun Hatazawa, Antony Gee, Osamu Inoue

    NEUROSCIENCE LETTERS　Vol. 415　No. 3　p. 259-263　2007/03

  20. Evaluation of [C-14]phenylacetate as a prototype tracer for the measurement of glial metabolism in the rat brain

    Osamu Inoue, Rie Hosoi, Sotaro Momosaki, Keisuke Yamamoto, Misato Amitani, Masatoshi Yamaguchi, Antony Gee

    NUCLEAR MEDICINE AND BIOLOGY　Vol. 33　No. 8　p. 985-989　2006/11

  21. Blood flow dependence of the intratumoral distribution of peripheral benzodiazepine receptor binding in intact mouse fibrosarcoma

    Misato Amitani, Ming-Rong Zhang, Junko Noguchi, Katsushi Kumata, Takeh Ito ito, Nobuhiko Takai, Kazutoshi Suzuki, Rie Hosoi, Osamu Inoue

    NUCLEAR MEDICINE AND BIOLOGY　Vol. 33　No. 8　p. 971-975　2006/11

  22. The apparent positive cooperativity of in vivo [H-3]PK-11195 binding in mouse fibrosarcoma

    Sotaro Momosaki, Rie Hosoi, Nobuhiko Takai, Antony Gee, Osamu Inoue

    NUCLEAR MEDICINE AND BIOLOGY　Vol. 33　No. 6　p. 797-800　2006/08

  23. Glial metabolic dysfunction caused neural damage by short-term ischemia in brain

    Rie Hosoi, Yuto Kashiwagi, Jun Hatazawa, Antony Gee, Osamu Inoue

    ANNALS OF NUCLEAR MEDICINE　Vol. 20　No. 5　p. 377-380　2006/06

  24. comparative measurement of in vivo and vitro receptor binding in the same rat brain

    Vol. 55, 29-33　2006

  25. 隣接切片を用いた同一個体脳切片におけるインビボ及びインビトロ受容体結合画像の比較測定法

    Radioisotopes　Vol. 55, 29-33　2006

  26. Distinct different intra-tumor distribution of FDG between early phase and late phase in mouse fibrosarcoma

    O Inoue, M Shukuri, R Hosoi, M Amitani, N Matsuura, J Hatazawa, N Takai

    ANNALS OF NUCLEAR MEDICINE　Vol. 19　No. 8　p. 655-659　2005/12

  27. Changes in in vivo [H-3]-Ro15-4513 binding induced by forced swimming in mice

    M Amitani, Y Umetani, R Hosoi, K Kobayashi, K Abe, O Inoue

    SYNAPSE　Vol. 58　No. 1　p. 23-29　2005/10

  28. MicroPET detection of enhanced F-18-FDG utilization by PKA inhibitor in awake rat brain

    R Hosoi, A Matsumura, S Mizokawa, M Tanaka, F Nakamura, K Kobayashi, Y Watanabe, O Inoue

    BRAIN RESEARCH　Vol. 1039　No. 1-2　p. 199-202　2005/03

  29. Effect of rolipram on relative C-14-deoxyglucose uptake in inflammatory lesions and skeletal muscle

    M Shukuri, M Terai, R Hosoi, T Nishimura, A Gee, O Inoue

    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING　Vol. 32　No. 2　p. 163-166　2005/02

  30. assessment of the metabolic trapping rate of FDG in rat brain using dual tracer autoradiography with 18F-FDG and 14C-FDG

    Vol. 54, 587-592　2005

  31. 18F-FDGおよび14C-FDGとのDual Tracer法を用いたラット脳糖代謝変化率の測定

    RADIOISOTOPES　Vol. 54, 587-592/,　2005

  32. Rat-PET study without anesthesia: Anesthetics modify the dopamine D-1 receptor binding in rat brain

    S Momosaki, K Hatano, Y Kawasumi, T Kato, R Hosoi, K Kobayashi, O Inoue, K Ito

    SYNAPSE　Vol. 54　No. 4　p. 207-213　2004/12

  33. Discrepancy between cell injury and benzodiazepine receptor binding after transient middle cerebral artery occlusion in rats

    K Abe, Y Kashiwagi, M Tokumura, R Hosoi, J Hatazawa, O Inoue

    SYNAPSE　Vol. 53　No. 4　p. 234-239　2004/09

  34. Effect of astrocytic energy metabolism depressant on C-14-acetate uptake in intact rat brain

    R Hosoi, M Okada, J Hatazawa, A Gee, O Inoue

    JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM　Vol. 24　No. 2　p. 188-190　2004/02

  35. Uncoupling of flow and metabolism induced by sodium nitroprusside in rat cerebral cortex

    O Inoue, H Taguchi, T Watanabe, R Hosoi, K Kobayashi, T Nishimura, A Gee

    NEUROREPORT　Vol. 15　No. 1　p. 141-145　2004/01

  36. Intrastriatal microinjection of sodium nitroprusside induces cell death and reduces binding of dopaminergic receptors

    K Yanamoto, R Hosoi, Y Uesaka, K Abe, H Tsukada, O Inoue

    SYNAPSE　Vol. 50　No. 2　p. 137-143　2003/11

  37. Ionic interaction of [C-11]-N, alpha-dimethylbenzylamine (DMBA) in rodent brain

    O Inoue, R Hosoi, S Momosaki, K Kobayashi, T Kida, K Suzuki, A Gee

    ANNALS OF NUCLEAR MEDICINE　Vol. 17　No. 6　p. 469-473　2003/09

  38. Sensitivities of benzodiazepine receptor binding and muscarinic acetylcholine receptor binding for the detection of neural cell death caused by sodium nitroprusside microinjection in rat brain

    O Inoue, K Yanamoto, Y Fujiwara, R Hosoi, K Kobayashi, H Tsukada

    SYNAPSE　Vol. 49　No. 2　p. 134-141　2003/08

  39. Effect of anesthetic drugs on the animal PET study in rat brain.

    S Momosaki, K Hatano, Y Kawasumi, T Kato, R Hosoi, O Inoue, K Ito

    JOURNAL OF NUCLEAR MEDICINE　Vol. 44　No. 5　p. 219P-219P　2003/05　Research paper, summary (international conference)

  40. Effect of sabcomeline on muscarinic and dopamine receptor binding in intact mouse brain

    Rie Hosoi, Kaoru Kobayashi, Junichi Ishida, Masatoshi Yamaguchi, Osamu Inoue

    Annals of Nuclear Medicine　Vol. 17　No. 2　p. 123-130　2003

    Publisher: Japanese Society of Nuclear Medicine

  41. Enhancement of the relative uptake of F-18-FDG in mouse fibrosarcoma by rolipram

    K Kobayashi, R Hosoi, S Momosaki, S Koike, K Ando, T Nishimura, O Inoue

    ANNALS OF NUCLEAR MEDICINE　Vol. 16　No. 7　p. 507-510　2002/11

  42. Increment of in vivo binding of [H-3]SCH 23390, a dopamine D-1 receptor ligand, induced by cyclic AMP-dependent protein kinase in rat brain

    K Abe, R Hosoi, S Momosaki, K Kobayashi, N Ibii, O Inoue

    BRAIN RESEARCH　Vol. 952　No. 2　p. 211-217　2002/10

  43. Rolipram depresses [H-3]2-deoxyglucose uptake in mouse brain and heart in vivo

    M Ishikawa, R Hosoi, K Kobayashi, T Nishimura, O Inoue

    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING　Vol. 29　No. 9　p. 1212-1215　2002/09

  44. Effects of rolipram on in vivo dopamine receptor binding

    R Hosoi, M Ishikawa, K Kobayashi, A Gee, M Yamaguchi, O Inoue

    JOURNAL OF NEURAL TRANSMISSION　Vol. 109　No. 9　p. 1139-1149　2002/09

  45. Changes in histological construction and decrease in H-3-QNB binding in the rat brain after prenatal X-irradiation

    S Momosaki, XZ Sun, N Takai, R Hosoi, O Inoue, S Takahashi

    JOURNAL OF RADIATION RESEARCH　Vol. 43　No. 3　p. 277-282　2002/09

  46. An important role of cAMP on ligand-receptor interactions in intact rat brain

    S Momosaki, K Yanamoto, R Hosoi, K Abe, N Ibii, O Inoue

    INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY　Vol. 17　p. S160-S161　2002/08　Research paper, summary (international conference)

  47. Short-term effects of cAMP-PKA system on 2-deoxyglucose uptake in intact brain

    R Hosoi, S Momosaki, M Ishikawa, K Abe, N Ibii, O Inoue

    INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY　Vol. 17　p. S160-S160　2002/08　Research paper, summary (international conference)

  48. Rolipram depresses [3H]2-deoxyglucose uptake in mouse brain and heart in vivo

    European Journal of Nuclear Medicine　Vol. 29, 1212-1215/,　2002

  49. Enhancement of the relative uptake of 18F-FDG in mouse fibrosarcoma by rolipram

    Kaoru Kobayashi, Rie Hosoi, Sotaro Momosaki, Sachiko Koike, Koichi Ando, Tsunehiko Nishimura, Osamu Inoue

    Annals of Nuclear Medicine　Vol. 16　No. 7　p. 507-510　2002

    Publisher: Japanese Society of Nuclear Medicine

  50. Changes in histological construction and decrese in 3H-QNB binding in the rat brain after prenatal X-irradiation

    Vol. 43(3):277-282　2002

  51. Rolipram depresses [3H]2-deoxyglucose uptake in mouse brain and heart in vivo

    Megumi Ishikawa, Rie Hosoi, Kaoru Kobayashi, Tsunehiko Nishimura, Osamu Inoue

    European Journal of Nuclear Medicine　Vol. 29　No. 9　p. 1212-1215　2002

  52. The role of the cAMP-PKA system in the short-term regulation of striatal [C-14]-2-deoxyglucose uptake in freely moving rats

    R Hosoi, S Momosaki, N Ibii, K Abe, T Itoh, O Inoue

    BRAIN RESEARCH　Vol. 921　No. 1-2　p. 260-263　2001/12

  53. Different sensitivities to competitive inhibition of benzodiazepine receptor binding of C-11-iomazenil and C-11-flumazenil in rhesus monkey brain

    O Inoue, R Hosoi, K Kobayashi, T Itoh, A Gee, K Suzuki

    ANNALS OF NUCLEAR MEDICINE　Vol. 15　No. 2　p. 137-139　2001/04

  54. オートアクチベーション及び放射性薬剤(18F-FOG及び11C-methionine)の診断能向上に関する検討

    平成12年度放射線医学総合研究所重粒子線がん治療装置等共同利用研究報告書　p. 60-61　2001

  55. 重粒子線照射による脳の機能障害に関する基礎検討

    平成11年度放射線医学総合研究所重粒子線がん治療装置等共同利用研究報告書　p. 78-79　2000

  56. PET、SPECT を用いた脳内レセプター.酵素と薬物の相互作用研究

    医薬品適正使用のための臨床薬物動態 月刊薬事2000年3月臨時増刊号　Vol. 42　No. 4　p. 581-586　2000

  57. Autoactivationおよびメチオニン残存集積に関する検討

    平成11年度放射線医学総合研究所重粒子線がん治療装置等共同利用研究報告書　p. 48-49　2000

  58. The effect of various pharmalogical perturbations on n vivo phosphodies (]G0004[) enzyme activity in the brain measured using [3H]-rolipram

    Supplement to Journal of Cerebral Blood Flow and Metabolism　Vol. 19　1999

  59. Evaluation of in vivo binding properties of 3H-NMPB and3H-QNB in mouse brain

    Journal of Neural Transmission　Vol. 106　p. 583-92　1999

  60. Effects of rolipram upon in vivo receptor binding in mice brain

    Supplement to Journal of Cerebral Blood Flow and Metabolism　Vol. 19　1999

  61. 重粒子線照射による脳の機能障害に関する基礎検討

    平成10年度放射線医学総合研究所重粒子線がん治療装置等共同利用研究報告書　p. 82-83　1999

  62. PETによる神経細胞とグリア細胞の弁別測定法の開発

    平成10年度放射線医学総合研究所重粒子線がん治療装置等共同利用研究報告書　p. 46-47　1999

  63. Discrepancy of benzodiazepine receptor occupancy between H-3-flumazenil and I-125-iomazenil in intact mouse brain

    R Hosoi, K Kobayashi, Y Watanabe, O Inoue

    JOURNAL OF NEURAL TRANSMISSION　Vol. 106　No. 3-4　p. 243-256　1999

  64. Discrepancies in apparent dopamine D2 receptor occupancy between H-3-raclopride and H-3-N-methylspiperone

    O Inoue, K Kobayashi, R Hosoi, M Yamaguchi, A Gee

    JOURNAL OF NEURAL TRANSMISSION　Vol. 106　No. 11-12　p. 1099-1104　1999

  65. Opposing effects of clomipramine on [I-125]RTI-55 and [H-3]N-methylspiperone binding in mouse striatum: Important role of other factors than endogenous dopamine?

    O Inoue, K Kobayashi, R Hosoi, A Gee

    SYNAPSE　Vol. 30　No. 3　p. 338-340　1998/11

  66. Modification of the serotonergic system alters benzodiazepine receptor binding in vivo

    NeuroImage　Vol. 7　No. 4　1998

  67. 重粒子線照射による脳の機能障害に関する基礎検討

    平成9年度放射線医学総合研究所重粒子がん治療装置等共同利用研究報告書　p. 163-164　1998

  68. PETによる神経細胞とグリア細胞の弁別測定法の開発

    平成9年度放射線医学総合研究所重粒子がん治療装置等共同利用研究報告書　p. 64-65　1998

  69. Effects of the GABAergic system on in vivo binding of [H-3]N-methylspiperone

    T Nakano, K Kobayashi, R Hosoi, S Wakahara, Y Watanabe, T Nishimura, O Inoue

    NEUROPHARMACOLOGY　Vol. 37　No. 3　p. 375-381　1998

  70. Changes in apparent in vivo binding of [3H]raclopride and [3H]N-methylspiperone induced by oxotremorine

    K. Kobayashi, A. Gee, R. Hosoi, O. Inoue

    Journal of Neural Transmission　Vol. 105　No. 10-12　p. 1193-1197　1998

  71. Isoform-specific up-regulation by ouabain of Na+,K+-ATPase in cultured rat astrocytes

    R Hosoi, T Matsuda, S Asano, H Nakamura, H Hashimoto, K Takuma, A Baba

    JOURNAL OF NEUROCHEMISTRY　Vol. 69　No. 5　p. 2189-2196　1997/11

  72. Discrepancies in Apparent Receptor Occupancies Measured by Two Different Radioligands

    Neurolmage　Vol. 5　No. 4　1997

  73. Involvement of Na+,K+-ATPase in the mitogenic effect of insulin-like growth factor-I on cultured rat astrocytes

    Toshio Matsuda, Yosuke Murata, Koh-Ichi Tanaka, Rie Hosoi, Masako Hayashi, Kazuko Tamada, Kazuhiro Takuma, Akemichi Baba

    Journal of Neurochemistry　Vol. 66　No. 2　p. 511-516　1996/02

  74. Ouabain-induced cell proliferation in cultured rat astrocytes

    Yosuke Murata, Toshio Matsuda, Kazuko Tamada, Rie Hosoi, Shoichi Asano, Kazuhiro Takuma, Koh-Ichi Tanaka, Akemichi Baba

    Japanese Journal of Pharmacology　Vol. 72　No. 4　p. 347-353　1996

    Publisher: Japanese Pharmacological Society

Presentations 7

  1. 幼若期マウス脳グリア細胞エネルギー代謝のペンチレンテトラゾール誘発けいれん発作時の亢進

    細井 理恵, 氏 雪乃, 安原 美緒, 小山内 実

    第144年会 日本薬学会　2024/03/30

  2. 経鼻投与法を用いたけいれん発作時の新生児マウス脳のグリア細胞エネルギー代謝画像の取得

    細井理恵, 多田健哉, 早川高弘, 芳賀優香, 田村篤史, 小山内実

    第143年会 日本薬学会　2023/03/26

  3. てんかん原性獲得過程におけるムスカリン性アセチルコリン受容体への選択的リガンド結合における2分子速度結合定数の変化の検討

    細井理恵, 中川直人, 別府恵実, 多田健哉, 田村篤史, 小山内実

    第142年会 日本薬学会　2022/03/27

  4. 経鼻投与法を用いた放射性分子プローブの新生児マウス脳移行性に関する検討

    細井理恵, 多田健哉, 田村篤史, 小山内実

    第61回日本核医学会総会　2021/11/04

  5. 経鼻投与法を用いた新生児マウス脳におけるグリア代謝画像の取得

    細井理恵, 多田健哉, 宮島大季, 田村篤史, 小山内実

    日本分子イメージング学会第15回学会総会・学術集会 / JSMI 2021　2021/05/26

  6. てんかん原性獲得過程におけるムスカリン性アセチルコリン受容体への3H-QNB結合

    細井 理恵, 宮島 大季, 多田 健哉, 小山内 実

    第141年会 日本薬学会　2021/03/28

  7. てんかん原性獲得過程におけるベンゾジアゼピン受容体およびムスカリン性アセチルコリン受容体結合の変化

    細井理恵

    第140年会 日本薬学会　2020/03/26

Works 6

  1. てんかんモデル動物におけるグリアイメージングの有用性に関する研究

    2009 -

  2. てんかんモデル動物におけるグリアイメージングの有用性に関する研究

    2008 -

  3. イメージングを用いた分子標的薬の腫瘍内分布に関する検討

    2007 -

  4. イメージングを用いた分子標的薬の腫瘍内分布に関する検討

    2006 -

  5. FDG-PETによる炎症組織の診断のための基礎的検討

    2005 -

  6. FDG-PETによる炎症組織の診断のための基礎的検討

    2004 -

Institutional Repository 2

Content Published in the University of Osaka Institutional Repository (OUKA)

  1. Ex-vivo Imaging of Glial Energy Metabolism in the Neonatal Mouse Brain during Convulsive Seizures with Intranasal Radiotracer Administration

    Hosoi Rie, Tada Kenya, Hayakawa Takahiro, Haga Yuka

    Molecular Imaging and Biology　2025/03/25

  2. 神経化学伝達物質受容体のマウス脳 in vivo リガンド結合に関する薬理学的研究

    細井 理恵