顔写真

PHOTO

Harada Kazuo
原田　和生
Harada Kazuo
原田　和生
Institutional repository
Graduate School of Pharmaceutical Sciences　Medical Pharmacy, Associate Professor

keyword Forensic toxicology，metabolic engineering，metabolomics，analytical chemistry

Institutional repository

Research History 10

  1. 2022/04 - Present
    Osaka University　Graduate School of Pharmaceutical Sciences　Associate Professor

  2. 2022/04 - Present
    Osaka University　Graduate School of Medicine, Legal Medicine

  3. 2017/12 - 2022/03
    Osaka University　Graduate School of Medicine

  4. 2017/12 - 2022/03
    Osaka University　Graduate School of Pharmaceutical Sciences

  5. 2017/04 - 2017/12
    大阪大学グローバルイニシアティブ・センター　講師

  6. 2014/04 - 2017/12
    Osaka University　Graduate School of Pharmaceutical Sciences, Experimental Institute for Medicinal Plants

  7. 2013/04 - 2014/03
    Osaka University　Graduate School of Pharmaceutical Sciences, Experimental Institute for Medicinal Plants

  8. 2011/04 - 2013/03
    Osaka University　Graduate School of Pharmaceutical Sciences

  9. 2008/04 - 2011/03
    Osaka University　Graduate School of Pharmaceutical Sciences, Center for Advanced Education and Research in Pharmaceutical Sciences

  10. 2007/02 - 2008/04
    Osaka University　Graduate School of Engineering

Education 3

  1. Osaka University

    - 2007

  2. Osaka University

    - 2004

  3. Osaka University　School of Engineering

    - 2002

Committee Memberships 3

  1. 日本生物工学会関西支部　委員　Academic society

    2011 - Present

  2. 生物工学若手研究者の集い　幹事　Academic society

    2009/09 - 2017/09

  3. 日本生物工学会　和文誌編集委員　Academic society

    2013/01 - 2017/05

Professional Memberships 6

  1. JAPANESE ASSOCIATION OF FORENSIC TOXICOLOGY

  2. THE PHARMACEUTICAL SOCIETY OF JAPAN

  3. THE JAPANESE SOCIETY OF PHARMACOGNOSY

  4. 日本中毒学会

  5. JAPANESE SOCIETY OF LEGAL MEDICINE

  6. 日本生物工学会

Research Areas 4

  1. Life sciences / Forensic medicine /

  2. Life sciences / Environmental and pharmaceutical development resources /

  3. Life sciences / Pharmaceuticals - health and biochemistry /

  4. Life sciences / Applied biochemistry /

Awards 2

  1. 第63回日本生薬学会年会 優秀発表賞

    原田和生, 上野菜摘, 小松かつ子, 平田收正　日本生薬学会　2016/09

  2. 日本生物工学会 第15回生物工学論文賞

    2007

Papers 97

  1. Correlation between the metabolic profile of Nelumbo Seed, a component of Seishinrenshiin, and its inhibitory activity on bladder smooth muscle contraction

    Kazuo Harada, Yuki Fukuda, Takahiro Ohkubo, Kimio Sugaya, Yukihiko Osaki

    Journal of Natural Medicines　2025/05　Research paper (scientific journal)

  2. Analysis of cyanide exposure status in fire-related deaths using a physiologically based pharmacokinetic model

    Kazuo Harada, Yuri Tokugawa, Kazunari Henmi, Yohei Miyashita, Yuji Sakahashi, Taichi Nishihori, Yukari Sakamoto, Chihpin Yang, Yu Isobe, Kana Sugimoto, Kentaro Nakama, Ryuichi Katada, Hiroshi Matsumoto

    Forensic Toxicology　2025/02/25　Research paper (scientific journal)

    Publisher: Springer Science and Business Media LLC

  3. Discovery of a Novel Lidocaine Metabolite by Human Liver Microsome and Identification of Microbial Species Which Produces the Same Metabolite

    Sho Hori, Hikari Taniguchi, Sota Yoshimura, Kanako Takeda, Ryusei Yamashita, Atsushi Kimishima, Kazuo Harada

    Chemical and Pharmaceutical Bulletin　Vol. 72　No. 4　p. 393-398　2024/04/19　Research paper (scientific journal)

    Publisher: Pharmaceutical Society of Japan

  4. Comparison of Quantitative Values of Headspace Gas Chromatography--Mass Spectrometry and a Formate Quantification Kit in Blood Formate Quantification

    Haruhi Yoshida, Kazuo Harada, Yukari Sakamoto, Jumpei Yoshimura, Takeshi Shimazu, Hiroshi Matsumoto

    Journal of Analytical Toxicology　Vol. 47　p. 338-345　2023/04/14　Research paper (scientific journal)

    Publisher: Oxford University Press (OUP)

  5. An Autopsy Case Report of Homicide by Methanol Intoxication With Pinkish Bilateral Putamina

    Motonori Takahashi, Takeshi Kondo, Gentaro Yamasaki, Marie Sugimoto, Haruhi Yoshida, Kazuo Harada, Hiroshi Matsumoto, Migiwa Asano, Yasuhiro Ueno

    American Journal of Forensic Medicine & Pathology　Vol. Publish Ahead of Print　2022/08/26　Research paper (scientific journal)

    Publisher: Ovid Technologies (Wolters Kluwer Health)

  6. Barium-induced toxic anterior segment syndrome

    Kenji Matsushita, Rumi Kawashima, Noriyasu Hashida, Yuki Hamano, Kazuo Harada, Kazuma Higashisaka, Koichi Baba, Shigeru Sato, Weiran Huang, Hiroshi Matsumoto, Teruhiko Hamanaka, Andrew J. Quantock, Kohji Nishida

    European Journal of Ophthalmology　p. 112067212110692-112067212110692　2021/12/30　Research paper (scientific journal)

  7. Monolayer platform using human biopsy-derived duodenal organoids for pharmaceutical research

    Tomoki Yamashita, Tatsuya Inui, Jumpei Yokota, Kentaro Kawakami, Gaku Morinaga, Masahito Takatani, Daisuke Hirayama, Ryuga Nomoto, Kohei Ito, Yunhai Cui, Stephanie Ruez, Kazuo Harada, Wataru Kishimoto, Hiroshi Nakase, Hiroyuki Mizuguchi

    Molecular Therapy - Methods & Clinical Development　Vol. 22　p. 263-278　2021/09　Research paper (scientific journal)

    Publisher: Elsevier BV

  8. In Vitro Model for a Drug Assessment of Cytochrome P450 Family 3 Subfamily A Member 4 Substrates Using Human Induced Pluripotent Stem Cells and Genome Editing Technology

    Sayaka Deguchi, Tomohiro Shintani, Kazuo Harada, Toru Okamoto, Akinori Takemura, Kazumasa Hirata, Kousei Ito, Kazuo Takayama, Hiroyuki Mizuguchi

    Hepatology Communications　Vol. 5　No. 8　p. 1385-1399　2021/08　Research paper (scientific journal)

  9. Activated microglia-derived macrophage-like cells exacerbate brain edema after ischemic stroke correlate with astrocytic expression of aquaporin-4 and interleukin-1 alpha release

    Yukie Murata, Kana Sugimoto, Chihpin Yang, Kazuo Harada, Rina Gono, Teiji Harada, Yohei Miyashita, Kazuma Higashisaka, Ryuichi Katada, Junya Tanaka, Hiroshi Matsumoto

    Neurochemistry International　Vol. 140　p. 104848-104848　2020/11　Research paper (scientific journal)

    Publisher: Elsevier BV

  10. Establishment of SLC15A1/PEPT1-Knockout Human-Induced Pluripotent Stem Cell Line for Intestinal Drug Absorption Studies

    Kanae Kawai, Ryosuke Negoro, Moe Ichikawa, Tomoki Yamashita, Sayaka Deguchi, Kazuo Harada, Kazumasa Hirata, Kazuo Takayama, Hiroyuki Mizuguchi

    Molecular Therapy - Methods & Clinical Development　Vol. 17　p. 49-57　2020/06　Research paper (scientific journal)

    Publisher: Elsevier BV

  11. Mycobacterium smegmatis alters the production of secondary metabolites by marine-derived Aspergillus niger

    Takahiro Jomori, Yasumasa Hara, Miho Sasaoka, Kazuo Harada, Andi Setiawan, Kazumasa Hirata, Atsushi Kimishima, Masayoshi Arai

    Journal of Natural Medicines　Vol. 74　No. 1　p. 76-82　2020/01/01　Research paper (scientific journal)

  12. 11β-hydroxysteroid dehydrogenase type 1 is associated with antiretroviral therapy-induced increase in low-density lipoprotein cholesterol

    Kazuyuki Niki, Kazuo Harada, Shinich Hikasa, Mamiko Tsugane, Mikiko Ueda, Satoshi Higasa, Takeshi Kimura, Tatsuya Takagi, Etsuko Uejima

    Int. Journal of Clinical Pharmacology and Therapeutics　Vol. 57　No. 6　p. 298-305　2019/06　Research paper (scientific journal)

    Publisher: Dustri-Verlgag Dr. Karl Feistle

  13. Modeling of Hepatic Drug Metabolism and Responses in CYP2C19 Poor Metabolizer Using Genetically Manipulated Human iPS cells.

    Sayaka Deguchi, Tomoki Yamashita, Keisuke Igai, Kazuo Harada, Yukiko Toba, Kazumasa Hirata, Kazuo Takayama, Hiroyuki Mizuguchi

    Drug metabolism and disposition: the biological fate of chemicals　Vol. 47　No. 6　p. 632-638　2019/06　Research paper (scientific journal)

  14. Generation of Human iPSC-Derived Intestinal Epithelial Cell Monolayers by CDX2 Transduction.

    Kazuo Takayama, Ryosuke Negoro, Tomoki Yamashita, Kanae Kawai, Moe Ichikawa, Takanori Mori, Noriyuki Nakatsu, Kazuo Harada, Sumito Ito, Hiroshi Yamada, Yoshiyuki Yamaura, Kazumasa Hirata, Seiichi Ishida, Hiroyuki Mizuguchi

    Cellular and molecular gastroenterology and hepatology　Vol. 8　No. 3　p. 513-526　2019　Research paper (scientific journal)

  15. Efficient Generation of Small Intestinal Epithelial-like Cells from Human iPSCs for Drug Absorption and Metabolism Studies.

    Ryosuke Negoro, Kazuo Takayama, Kanae Kawai, Kazuo Harada, Fuminori Sakurai, Kazumasa Hirata, Hiroyuki Mizuguchi

    Stem cell reports　Vol. 11　No. 6　p. 1539-1550　2018/12/11　Research paper (scientific journal)

  16. Molecular Components of Arabidopsis Intact Vacuoles Clarified with Metabolomic and Proteomic Analyses.

    Miwa Ohnishi, Aya Anegawa, Yuko Sugiyama, Kazuo Harada, Akira Oikawa, Yasumune Nakayama, Fumio Matsuda, Yukiko Nakamura, Ryosuke Sasaki, Chizuko Shichijo, Patrick G Hatcher, Hidehiro Fukaki, Shigehiko Kanaya, Koh Aoki, Mami Yamazaki, Eiichiro Fukusaki, Kazuki Saito, Tetsuro Mimura

    Plant & cell physiology　Vol. 59　No. 7　p. 1353-1362　2018/07/01　Research paper (scientific journal)

  17. Residues of 2-hydroxy-3-phenylpyrazine, a degradation product of some beta-lactam antibiotics, in environmental water in Vietnam

    Nguyen Van Sy, Kazuo Harada, Megumi Asayama, Minae Warisaya, Le Hong Dung, Yoshinori Sumimura, Khong Thi Diep, Le Viet Ha, Nguyen Nam Thang, Tran Thi Tuyet Hoa, Tran Minh Phu, Pham Ngoc Khai, Nguyen Thanh Phuong, Le Danh Tuyen, Yoshimasa Yamamoto, Kazumasa Hirata

    CHEMOSPHERE　Vol. 172　p. 355-362　2017/04　Research paper (scientific journal)

  18. Water metagenomic analysis reveals low bacterial diversity and the presence of antimicrobial residues and resistance genes in a river containing wastewater from backyard aquacultures in the Mekong Delta, Vietnam

    Tatsuya Nakayama, Tran Thi Tuyet Hoa, Kazuo Harada, Minae Warisaya, Megumi Asayama, Atsushi Hinenoya, Joon Won Lee, Tran Minh Phu, Shuhei Ueda, Yoshinori Sumimura, Kazumasa Hirata, Nguyen Thanh Phuong, Yoshimasa Yamamoto

    ENVIRONMENTAL POLLUTION　Vol. 222　p. 294-306　2017/03　Research paper (scientific journal)

  19. Pharmacokinetics of loxoprofen and cefcapene following a single combined dose in healthy volunteers before, during or immediately after 120-min enteral tube feeding of 400 mL Ensure Liquid®

    Mikiko Ueda, Kazuo Harada, Kenji Ikeda, Minako Ohishi, Maria Kitamura, Hiroko Ueda, Katsumi Azenishi, Setsu Inatsuki, Kazunori Niki, Chisato Okajima, Mamoru Tempaku, Yuki Fukuda, Saki Yoshida, Kazumasa Hirata, Shinichiro Suna, Kazusaburo Kataoka, Mikihiko Kogo, Etsuko Uejima

    Japanese Journal of Clinical Pharmacology and Therapeutics　Vol. 48　No. 6　p. 185-193　2017　Research paper (scientific journal)

    Publisher: Japanese Society of Clinical Pharmacology and Therapeutics

  20. Enhanced production of nojirimycin via Streptomyces ficellus cultivation using marine broth and inhibitory activity of the culture for seeds of parasitic weeds

    Kazuo Harada, Yurika Kurono, Saya Nagasawa, Tomoka Oda, Yudai Nasu, Takatoshi Wakabayashi, Yukihiro Sugimoto, Hideyuki Matsuura, Satoru Muranaka, Kazumasa Hirata, Atsushi Okazawa

    JOURNAL OF PESTICIDE SCIENCE　Vol. 42　No. 3-4　p. 166-171　2017　Research paper (scientific journal)

  21. Monitoring of Antibiotic Residues in Aquatic Products in Urban and Rural Areas of Vietnam

    Kotaro Uchida, Yoshimasa Konishi, Kazuo Harada, Masahiro Okihashi, Takahiro Yamaguchi, Mai Hoang Ngoc Do, Long Thi Bui, Thinh Duc Nguyen, Phuc Do Nguyen, Diep Thi Khong, Hoa Thi Tran, Thang Nam Nguyen, Ha Viet Le, Vien Van Chau, Khanh Thi Van Dao, Hue Thi Ngoc Nguyen, Keiji Kajimura, Yuko Kumeda, Khanh Tran Pham, Khai Ngoc Pham, Chien Trong Bui, Mai Quang Vien, Ninh Hoang Le, Chinh Van Dang, Kazumasa Hirata, Yoshimasa Yamamoto

    JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY　Vol. 64　No. 31　p. 6133-6138　2016/08　Research paper (scientific journal)

  22. Longgu (Fossilia Ossis Mastodi) alters the profiles of organic and inorganic components in Keishikaryukotsuboreito

    Kazuki Oguri, Masaya Kawase, Kazuo Harada, Kayoko Shimada-Takaura, Toshiharu Takahashi, Kyoko Takahashi

    JOURNAL OF NATURAL MEDICINES　Vol. 70　No. 3　p. 483-491　2016/07　Research paper (scientific journal)

  23. Spread of antibiotic and antimicrobial susceptibility of ESBL-producing Escherichia coli isolated from wild and cultured fish in the Mekong Delta, Vietnam

    Nguyen Thi Ngoc Hon, Tran Thi Tuyet Hoa, Nguyen Quoc Thinh, Atsushi Hinenoya, Tatsuya Nakayama, Kazuo Harada, Megumi Asayama, Minae Warisaya, Kazumasa Hirata, Nguyen Thanh Phuong, Yoshimasa Yamamoto

    Fish Pathology　Vol. 51　p. S75-S82　2016　Research paper (scientific journal)

    Publisher: Japanese Society of Fish Pathology

  24. Antibiotic Residue Monitoring Results for Pork, Chicken, and Beef Samples in Vietnam in 2012-2013

    Takahiro Yamaguchi, Masahiro Okihashi, Kazuo Harada, Yoshimasa Konishi, Kotaro Uchida, Mai Hoang Ngoc Do, Huong Dang Thien Bui, Thinh Duc Nguyen, Phuc Do Nguyen, Vien Van Chau, Khanh Thi Van Dao, Hue Thi Ngoc Nguyen, Keiji Kajimura, Yuko Kumeda, Chien Trong Bui, Mai Quang Vien, Ninh Hoang Le, Kazumasa Hirata, Yoshimasa Yamamoto

    JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY　Vol. 63　No. 21　p. 5141-5145　2015/06　Research paper (scientific journal)

  25. Rapid and Easy Multiresidue Method for the Analysis of Antibiotics in Meats by Ultrahigh-Performance Liquid Chromatography-Tandem Mass Spectrometry

    Takahiro Yamaguchi, Masahiro Okihashi, Kazuo Harada, Kotaro Uchida, Yoshimasa Konishi, Keiji Kajimura, Kazumasa Hirata, Yoshimasa Yamamoto

    JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY　Vol. 63　No. 21　p. 5133-5140　2015/06　Research paper (scientific journal)

  26. Prediction of interindividual differences in hepatic functions and drug sensitivity by using human iPS-derived hepatocytes

    Kazuo Takayama, Yuta Morisaki, Shuichi Kuno, Yasuhito Nagamoto, Kazuo Harada, Norihisa Furukawa, Manami Ohtaka, Ken Nishimura, Kazuo Imagawa, Fuminori Sakurai, Masashi Tachibana, Ryo Sumazaki, Emiko Noguchi, Mahito Nakanishi, Kazumasa Hirata, Kenji Kawabata, Hiroyuki Mizuguchi

    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA　Vol. 111　No. 47　p. 16772-16777　2014/11　Research paper (scientific journal)

  27. Commensal Bacteria-Dependent Indole Production Enhances Epithelial Barrier Function in the Colon

    Yosuke Shimada, Makoto Kinoshita, Kazuo Harada, Masafumi Mizutani, Kazunori Masahata, Hisako Kayama, Kiyoshi Takeda

    PLOS ONE　Vol. 8　No. 11　2013/11　Research paper (scientific journal)

  28. Isolation of polyphenol oxidase genes from Portulaca oleracea and evaluation of their ability to metabolize endocrine-disrupting chemicals

    Hirokazu Kaneda, Takeshi Matsui, Ryosuke Tomiyasu, Yukako Kuroda, Yuka Higashimoto, Tomoka Oda, Hitoshi Miyasaka, Hiroshi Okuhata, Satoshi Tanaka, Kazuo Harada, Hideyuki Matsuura, Hideki Nakayama, Ko Kato, Kazumasa Hirata

    PLANT BIOTECHNOLOGY　Vol. 29　No. 4　p. 351-357　2012　Research paper (scientific journal)

  29. Toxicological characterization of N-methyl-N-nitrosourea-induced cataract in rats by LC/MS-based metabonomic analysis

    Yuko Miyazono, Kazuo Harada, Koji Sugiyama, Motonobu Ueno, Mikinori Torii, Ikuo Kato, Hideyuki Matsuura, Kazumasa Hirata

    JOURNAL OF APPLIED TOXICOLOGY　Vol. 31　No. 7　p. 655-662　2011/10　Research paper (scientific journal)

  30. Metabolic turnover analysis by a combination of in vivo C-13-labelling from (CO2)-C-13 and metabolic profiling with CE-MS/MS reveals rate-limiting steps of the C-3 photosynthetic pathway in Nicotiana tabacum leaves

    Tomohisa Hasunuma, Kazuo Harada, Shin-Ichi Miyazawa, Akihiko Kondo, Eiichiro Fukusaki, Chikahiro Miyake

    JOURNAL OF EXPERIMENTAL BOTANY　Vol. 61　No. 4　p. 1041-1051　2010/03　Research paper (scientific journal)

  31. Quantitative analysis of anionic metabolites for Catharanthus roseus by capillary electrophoresis using sulfonated capillary coupled with electrospray ionization-tandem mass spectrometry

    Kazuo Harada, Yohko Ohyama, Tetsuya Tabushi, Akio Kobayashi, Eiichiro Fukusaki

    JOURNAL OF BIOSCIENCE AND BIOENGINEERING　Vol. 105　No. 3　p. 249-260　2008/03　Research paper (scientific journal)

  32. In vivo N-15-enrichment of metabolites in suspension cultured cells and its application to metabolomics

    Kazuo Harada, Eiichiro Fukusaki, Takeshi Bamba, Fumihiko Sato, Akio Kobayashi

    BIOTECHNOLOGY PROGRESS　Vol. 22　No. 4　p. 1003-1011　2006/08　Research paper (scientific journal)

  33. Pressure-assisted capillary electrophoresis mass spectrometry using combination of polarity reversion and electroosmotic flow for metabolomics anion analysis

    Kazuo Harada, Eiichiro Fukusaki, Akio Kobayashi

    JOURNAL OF BIOSCIENCE AND BIOENGINEERING　Vol. 101　No. 5　p. 403-409　2006/05　Research paper (scientific journal)

  34. Structural analysis and molecular dynamics simulations of urease from Ureaplasma parvum

    Heng Ning Wu, Junso Fujita, Yukiko Nakura, Masao Inoue, Koichiro Suzuki, Toru Ekimoto, Bingjie Yin, Yohta Fukuda, Kazuo Harada, Tsuyoshi Inoue, Mitsunori Ikeguchi, Keiichi Namba, Itaru Yanagihara

    Journal of Molecular Biology　2025/08　Research paper (scientific journal)

  35. Photocatalytic Multiple Deuteration of Polyethylene Glycol Derivatives Using Deuterium Oxide

    Riku Ogasahara, Miyu Mae, Keisuke Matsuura, Sota Yoshimura, Takayoshi Ishimoto, Taro Udagawa, Kazuo Harada, Hiroyoshi Fujioka, Mako Kamiya, Rio Asada, Hiromasa Uchiyama, Yuichi Tozuka, Shuji Akai, Yoshinari Sawama

    Chemistry – A European Journal　2025/01/07　Research paper (scientific journal)

    Publisher: Wiley

  36. Chemical Constituents and Anticancer Activities of Marine-Derived Fungus Trichoderma lixii

    Natchanun Sirimangkalakitti, Jianyu Lin, Kazuo HARADA, Andi Setiawan, Mitsuhiro ARISAWA, Masayoshi Arai

    Molecules　Vol. 29　2024/04/29　Research paper (scientific journal)

  37. Polyglycerol fatty acid ester contributes to the improvement and maintenance of water solubility of amorphous curcumin by suppressing the intermolecular interaction and the diffusion rate of curcumin.

    Kazuya Nagano, Tomohiro Nakao, Mariko Takeda, Haruna Hirai, Hikaru Maekita, Michiko Nakamura, Naoki Imakawa, Ayako Egawa, Toshimichi Fujiwara, Jian-Qing Gao, Keigo Kinoshita, Makoto Sakata, Masayuki Nishino, Takuya Yamashita, Takuya Yoshida, Kazuo Harada, Keisuke Tachibana, Takefumi Doi, Kazumasa Hirata, Hirofumi Tsujino, Kazuma Higashisaka, Yasuo Tsutsumi

    Food chemistry　Vol. 437　No. Pt 2　p. 137866-137866　2024/03/30　Research paper (scientific journal)

  38. Molecular mechanism of cerebral edema improvement via IL-1RA released from the stroke-unaffected hindlimb by treadmill exercise after cerebral infarction in rats.

    Rina Gono, Kana Sugimoto, Chihpin Yang, Yukie Murata, Reiko Nomura, Mai Shirazaki, Kazuo Harada, Teiji Harada, Yohei Miyashita, Kazuma Higashisaka, Ryuichi Katada, Hiroshi Matsumoto

    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism　2023/01/18　Research paper (scientific journal)

  39. One-step antibacterial modification of polypropylene non-woven fabrics via oxidation using photo-activated chlorine dioxide radicals

    Keita Yamamoto, Haruyasu Asahara, Kazuo Harada, Yuki Itabashi, Kei Ohkubo, Tsuyoshi Inoue

    Journal of Materials Chemistry B　Vol. 11　No. 23　p. 5101-5107　2023　Research paper (scientific journal)

    Publisher: Royal Society of Chemistry (RSC)

  40. Ligand-free reductive coupling of aldehydes with 1,3-dienes using a sulfur-modified Au-supported nickel nanoparticle catalyst

    Ryosuke Ohta, Yasunori Shio, Toshiki Akiyama, Makito Yamada, Kazuo Harada, Mitsuhiro Arisawa

    New Journal of Chemistry　Vol. 47　No. 16　p. 7694-7700　2023　Research paper (scientific journal)

    Publisher: Royal Society of Chemistry (RSC)

  41. A New Tetracyclic Bromopyrrole-Imidazole Derivative through Direct Chemical Diversification of Substances Present in Natural Product Extract from Marine Sponge Petrosia (Strongylophora) sp.

    Natchanun Sirimangkalakitti, Kazuo HARADA, Makito Yamada, Masayoshi Arai, Mitsuhiro ARISAWA

    Molecules　Vol. 28　No. 1　p. 143-143　2022/12/24　Research paper (scientific journal)

    Publisher: MDPI AG

  42. Design, Synthesis, and Monoamine Oxidase B Selective Inhibitory Activity of N-Arylated Heliamine Analogues

    Makito Yamada, Yu Hirose, Bangzhong Lin, Megumi Fumimoto, Kazuto Nunomura, Sirimangkalakitti Natchanun, Naoyuki Takahashi, Yuuta Ohki, Makoto Sako, Kenichi Murai, Kazuo Harada, Masayoshi Arai, Sayo Suzuki, Tomonori Nakamura, Junichi Haruta, Mitsuhiro Arisawa

    ACS Medicinal Chemistry Letters　2022/08/22　Research paper (scientific journal)

    Publisher: American Chemical Society (ACS)

  43. Carbon(sp 2 )‐carbon(sp 3 ) Bond‐forming Cross‐coupling Reactions Using Sulfur‐Modified Au‐Supported Nickel Nanoparticle Catalyst

    Ryousuke Ohta, Yasunori Shio, Toshiki Akiyama, Makito Yamada, Shuhei Shimoda, Kazuo Harada, Makoto Sako, Jun‐ya Hasegawa, Mitsuhiro Arisawa

    Asian Journal of Organic Chemistry　2022/07/13　Research paper (scientific journal)

    Publisher: Wiley

  44. Product selective reaction controlled by the combination of palladium nanoparticles, continuous microwave irradiation, and a co-existing solid; ligand-free Buchwald-Hartwig amination vs. aryne amination

    Makito Yamada, Ryousuke Ohta, Kazuo Harada, Tsunayoshi Takehara, Hitoshi Haneoka, Yosuke Murakami, Takeyuki Suzuki, Yuuta Ohki, Naoyuki Takahashi, Toshiki Akiyama, Natchanun Sirimangkalakitti, Makoto Sako, Kenichi Murai, Masayoshi Arai, Mitsuhiro Arisawa

    GREEN CHEMISTRY　2021/08　Research paper (scientific journal)

  45. Preparation of a platinum nanoparticle catalyst located near photocatalyst titanium oxide and its catalytic activity to convert benzyl alcohols to the corresponding ethers

    Yuki Wada, Toshiki Akiyama, Kazuo Harada, Tetsuo Honma, Hiroshi Naka, Susumu Saito, Mitsuiro Arisawa

    RSC Advances　Vol. 11　No. 36　p. 22230-22237　2021　Research paper (scientific journal)

    Publisher: Royal Society of Chemistry ({RSC})

  46. Development and Evaluation of a System for the Semi-Quantitative Determination of the Physical Properties of Skin After Exposure to Silver Nanoparticles

    Tao, H., Nagano, K., Tasaki, I., Zhang, T.-Q., Ishizaka, T., Gao, J.-Q., Harada, K., Hirata, K., Tsujino, H., Higashisaka, K., Tsutsumi, Y.

    Nanoscale Research Letters　Vol. 15　No. 1　2020/12　Research paper (scientific journal)

    Publisher: Springer Science and Business Media LLC

  47. Molecular mechanisms of Wischnewski spot development on gastric mucosa in fatal hypothermia: an experimental study in rats

    Chihpin Yang, Kana Sugimoto, Yukie Murata, Yuichiro Hirata, Yu Kamakura, Yoshihisa Koyama, Yohei Miyashita, Kentaro Nakama, Kazuma Higashisaka, Kazuo Harada, Ryuichi Katada, Hiroshi Matsumoto

    Scientific Reports　Vol. 10　No. 1　p. 1877-1877　2020/12　Research paper (scientific journal)

    Publisher: Springer Science and Business Media LLC

  48. Self-Assembled Multilayer Iron(0) Nanoparticle Catalyst for Ligand-Free Carbon–Carbon/Carbon–Nitrogen Bond-Forming Reactions

    Toshiki Akiyama, Yuki Wada, Makito Yamada, Yasunori Shio, Tetsuo Honma, Shuhei Shimoda, Kazuki Tsuruta, Yusuke Tamenori, Hitoshi Haneoka, Takeyuki Suzuki, Kazuo Harada, Hayato Tsurugi, Kazushi Mashima, Jun-ya Hasegawa, Yoshihiro Sato, Mitsuhiro Arisawa

    Organic Letters　Vol. 22　No. 18　p. 7244-7249　2020/09/18　Research paper (scientific journal)

  49. Development and evaluation of a simultaneous and efficient quantification strategy for final prostanoid metabolites in urine

    Zhang, T.-Q., Kuroda, H., Nagano, K., Terada, S., Gao, J.-Q., Harada, K., Hirata, K., Tsujino, H., Higashisaka, K., Matsumoto, H., Tsutsumi, Y.

    Prostaglandins Leukotrienes and Essential Fatty Acids　Vol. 157　p. 102032-102032　2020/06　Research paper (scientific journal)

    Publisher: Elsevier BV

  50. Direct visualization of an antidepressant analog using surface-enhanced Raman scattering in the brain

    Masato Tanuma, Atsushi Kasai, Kazuki Bando, Naoyuki Kotoku, Kazuo Harada, Masafumi Minoshima, Kosuke Higashino, Atsushi Kimishima, Masayoshi Arai, Yukio Ago, Kaoru Seiriki, Kazuya Kikuchi, Satoshi Kawata, Katsumasa Fujita, Hitoshi Hashimoto

    JCI Insight　Vol. 5　No. 6　2020/03/26　Research paper (scientific journal)

    Publisher: American Society for Clinical Investigation

  51. Comparison of commercially available media for hepatic differentiation and hepatocyte maintenance

    Yukiko Toba, Sayaka Deguchi, Natsumi Mimura, Ayaka Sakamoto, Kazuo Harada, Kazumasa Hirata, Kazuo Takayama, Hiroyuki Mizuguchi

    PLOS ONE　Vol. 15　No. 2　p. e0229654-e0229654　2020/02/27　Research paper (scientific journal)

    Publisher: Public Library of Science (PLoS)

  52. Optimization and Evaluation of Pretreatment Method for sp-ICP-MS to Reveal the Distribution of Silver Nanoparticles in the Body

    Ishizaka, T., Nagano, K., Tasaki, I., Tao, H., Gao, J.-Q., Harada, K., Hirata, K., Saito, S., Tsujino, H., Higashisaka, K., Tsutsumi, Y.

    Nanoscale Research Letters　Vol. 14　No. 1　2019/12　Research paper (scientific journal)

    Publisher: Springer Science and Business Media LLC

  53. Extended-spectrum beta-lactamase-producing Escherichia coli harbouring sul and mcr-1 genes isolates from fish gut contents in the Mekong Delta, Vietnam

    T. T.T. Hoa, T. Nakayama, H. M. Huyen, K. Harada, A. Hinenoya, N. T. Phuong, Y. Yamamoto

    Letters in Applied Microbiology　2019　Research paper (scientific journal)

  54. Class III polyphosphate kinase 2 enxymes catalyze the pyrophosphorylation of adenosine-5’-monophosphate

    Ogawa, M, Uyeda, A, Harada, K, Sato, Y, Kato, Y, Watanabe, H, Honda, K, Matsuura, T

    ChemBioChem　Vol. 20　No. 23　p. 2961-2967　2019　Research paper (scientific journal)

  55. Development of a paper-based luminescence bioassay for therapeutic monitoring of aminoglycosides: a proof-of-concept study

    Matsuura, H, Ujiie, K, Duyen, T. T. M, Izutsu, K, Fujiyama, K, Maeda, S, Harada, K, Hirata, K

    Appl. Biochem. Biotech.　Vol. 189　No. 3　p. 798-809　2019　Research paper (scientific journal)

  56. Paper-based luminescence bioassay method embedding a sequence of enzymatic reactions to detect sulfonamide groups.

    Kazuki Ujiie, Hideyuki Matsuura, Tran Thi My Duyen, Koki Izutsu, Ayaka Nitta, Kazuo Harada, Kazumasa Hirata

    The Journal of antibiotics　Vol. 71　No. 12　p. 1044-1047　2018/08　Research paper (scientific journal)

  57. The presence of colistin resistance gene mcr-1 and -3 in ESBL producing Escherichia coli isolated from food in Ho Chi Minh City, Vietnam

    Takahiro Yamaguchi, Ryuji Kawahara, Kazuo Harada, Shihono Teruya, Tatsuya Nakayama, Daisuke Motooka, Shota Nakamura, Phuc Do Nguyen, Yuko Kumeda, Chinh Van Dang, Kazumasa Hirata, Yoshimasa Yamamoto

    FEMS Microbiology Letters　Vol. 365　No. 11　2018/06/01　Research paper (scientific journal)

    Publisher: Oxford University Press

  58. Generation of a bile salt export pump deficiency model using patient-specific induced pluripotent stem cell-derived hepatocyte-like cells

    Kazuo Imagawa, Kazuo Takayama, Shigemi Isoyama, Ken Tanikawa, Masato Shinkai, Kazuo Harada, Masashi Tachibana, Fuminori Sakurai, Emiko Noguchi, Kazumasa Hirata, Masayoshi Kage, Kenji Kawabata, Ryo Sumazaki, Hiroyuki Mizuguchi

    Scientific Reports　Vol. 7　2017/02　Research paper (scientific journal)

  59. AlkB homolog 3-mediated tRNA demethylation promotes protein synthesis in cancer cells

    Yuko Ueda, Ikumi Ooshio, Yasuyuki Fusamae, Kaori Kitae, Megumi Kawaguchi, Kentaro Jingushi, Hiroaki Hase, Kazuo Harada, Kazumasa Hirata, Kazutake Tsujikawa

    SCIENTIFIC REPORTS　Vol. 7　2017/02　Research paper (scientific journal)

  60. Detection of antibiotics in chicken eggs obtained from supermarkets in Ho Chi Minh City, Vietnam

    Takahiro Yamaguchi, Masahiro Okihashi, Kazuo Harada, Yoshimasa Konishi, Kotaro Uchida, Mai Hoang Ngoc Do, Long Thi Bui, Thinh Duc Nguyen, Ha Bich Phan, Huong Dang Thien Bui, Phuc Do Nguyen, Keiji Kajimura, Yuko Kumeda, Chinh Van Dang, Kazumasa Hirata, Yoshimasa Yamamoto

    JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART B-PESTICIDES FOOD CONTAMINANTS AND AGRICULTURAL WASTES　Vol. 52　No. 6　p. 430-433　2017　Research paper (scientific journal)

  61. Paper-based colorimetric biosensor for antibiotics inhibiting bacterial protein synthesis

    Tran Thi My Duyen, Hideyuki Matsuura, Kazuki Ujiie, Misa Muraoka, Kazuo Harada, Kazumasa Hirata

    JOURNAL OF BIOSCIENCE AND BIOENGINEERING　Vol. 123　No. 1　p. 96-100　2017/01　Research paper (scientific journal)

  62. Optimization of 3', 4'-anhydrovinblastine synthesis in vitro using crude extracts of catharanthus roseus irradiated with near-ultraviolet light

    Asano, M., Harada, K., Umeno, A., Hirata, K.

    Natural Product Communications　Vol. 11　No. 8　p. 1089-1092　2016/12　Research paper (scientific journal)

  63. Screening of antibiotic residues in pork meat in Ho Chi Minh City, Vietnam, using a microbiological test kit and liquid chromatography/tandem mass spectrometry

    Mai Hoang Ngoc, Takahiro Yamaguchi, Masahiro Okihashi, Kazuo Harada, Yoshimasa Konishi, Kotaro Uchida, Long Thi Bui, Thinh Duc Nguyen, Ha Bich Phan, Huong Dang Thien Bui, Phuc Do Nguyen, Keiji Kajimura, Yuko Kumeda, Chinh Van Dang, Kazumasa Hirata, Yoshimasa Yamamoto

    FOOD CONTROL　Vol. 69　p. 262-266　2016/11　Research paper (scientific journal)

  64. A real-time PCR-based quantitative assay for 3-methylcytosine demethylase activity of ALKBH3

    Yuko Ueda, Kaori Kitae, Ikumi Ooshio, Yasuyuki Fusamae, Megumi Kawaguchi, Kentaro Jingushi, Kazuo Harada, Kazumasa Hirata, Kazutake Tsujikawa

    Biochemistry and Biophysics Reports　Vol. 5　p. 476-481　2016/03/01　Research paper (scientific journal)

    Publisher: Elsevier

  65. Planteose as a storage carbohydrate required for early stage of germination of Orobanche minor and its metabolism as a possible target for selective control

    Takatoshi Wakabayashi, Benesh Joseph, Shuhei Yasumoto, Tomoyoshi Akashi, Toshio Aoki, Kazuo Harada, Satoru Muranaka, Takeshi Bamba, Eiichiro Fukusaki, Yasutomo Takeuchi, Koichi Yoneyama, Toshiya Muranaka, Yukihiro Sugimoto, Atsushi Okazawa

    JOURNAL OF EXPERIMENTAL BOTANY　Vol. 66　No. 11　p. 3085-3097　2015/06　Research paper (scientific journal)

  66. Immobilization of enzymatic extracts of Portulaca oleracea cv. roots for oxidizing aqueous bisphenol A

    Kazuki Matsushima, Hirokazu Kaneda, Kazuo Harada, Hideyuki Matsuura, Kazumasa Hirata

    BIOTECHNOLOGY LETTERS　Vol. 37　No. 5　p. 1037-1042　2015/05　Research paper (scientific journal)

  67. Glutamate Acts as a Key Signal Linking Glucose Metabolism to Incretin/cAMP Action to Amplify Insulin Secretion

    Ghupurjan Gheni, Masahito Ogura, Masahiro Iwasaki, Norihide Yokoi, Kohtaro Minami, Yasumune Nakayama, Kazuo Harada, Benoit Hastoy, Xichen Wu, Harumi Takahashi, Kazushi Kimura, Toshiya Matsubara, Ritsuko Hoshikawa, Naoya Hatano, Kenji Sugawara, Tadao Shibasaki, Nobuya Inagaki, Takeshi Bamba, Akira Mizoguchi, Eiichiro Fukusaki, Patrik Rorsman, Susumu Seino

    CELL REPORTS　Vol. 9　No. 2　p. 661-673　2014/10　Research paper (scientific journal)

  68. Metabolite profiles of polyhydroxyalkanoate-producing Ralstonia eutropha H16

    Toshiaki Fukui, Kenta Chou, Kazuo Harada, Izumi Orita, Yasumune Nakayama, Takeshi Bamba, Satoshi Nakamura, Eiichiro Fukusaki

    METABOLOMICS　Vol. 10　No. 2　p. 190-202　2014/04　Research paper (scientific journal)

  69. Functional characterization of a carotenoid cleavage dioxygenase 1 gene from Chlamydomonas reinhardtii

    Ogata, T, Matsuura, H, Ishida, H, Matsuda, Y, Shintoku, M, Takeno, J. K, Onda, Y, Bamba, T, Fukusaki, E, Harada, K, Hirata, K

    Catotenoid Science　Vol. 19　p. 28-32　2014/03　Research paper (scientific journal)

  70. Effects of elevated pressure on rate of photosynthesis during plant growth

    Hiroyuki Takeishi, Jun Hayashi, Atsushi Okazawa, Kazuo Harada, Kazumasa Hirata, Akio Kobayashi, Fumiteru Akamatsu

    JOURNAL OF BIOTECHNOLOGY　Vol. 168　No. 2　p. 135-141　2013/10　Research paper (scientific journal)

  71. Development of Surface-Engineered Yeast Cells Displaying Phytochelatin Synthase and Their Application to Cadmium Biosensors by the Combined Use of Pyrene-Excimer Fluorescence

    Hideyuki Matsuura, Yosuke Yamamoto, Misa Muraoka, Kenji Akaishi, Yasuhisa Hori, Kanoko Uemura, Naoki Tsuji, Kazuo Harada, Kazumasa Hirata, Takeshi Bamba, Hitoshi Miyasaka, Kouichi Kuroda, Mitsuyoshi Ueda

    BIOTECHNOLOGY PROGRESS　Vol. 29　No. 5　p. 1197-1202　2013/09　Research paper (scientific journal)

  72. Green leaf volatiles enhance methyl jasmonate response in Arabidopsis

    Toshihiro Hirao, Atsushi Okazawa, Kazuo Harada, Akio Kobayashi, Toshiya Muranaka, Kazumasa Hirata

    JOURNAL OF BIOSCIENCE AND BIOENGINEERING　Vol. 114　No. 5　p. 540-545　2012/11　Research paper (scientific journal)

  73. High-accuracy analysis system for the redox status of coenzyme Q(10) by online supercritical fluid extraction-supercritical fluid chromatography/mass spectrometry

    Atsuki Matsubara, Kazuo Harada, Kazumasa Hirata, Eiichiro Fukusaki, Takeshi Bamba

    JOURNAL OF CHROMATOGRAPHY A　Vol. 1250　p. 76-79　2012/08　Research paper (scientific journal)

  74. Characterization of Bisphenol A Metabolites Produced by Portulaca oleracea cv. by Liquid Chromatography Coupled with Tandem Mass Spectrometry

    Ippei Watanabe, Kazuo Harada, Takeshi Matsui, Hitoshi Miyasaka, Hiroshi Okuhata, Satoshi Tanaka, Hideki Nakayama, Ko Kato, Takeshi Bamba, Kazumasa Hirata

    BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY　Vol. 76　No. 5　p. 1015-1017　2012/05　Research paper (scientific journal)

  75. Comparison of three Chlamydomonas strains which show distinctive oxidative stress tolerance

    Satoshi Tanaka, Kazunori Ikeda, Hitoshi Miyasaka, Yuzo Shioi, Yoshimi Suzuki, Masahiro Tamoi, Toru Takeda, Shigeru Shigeoka, Kazuo Harada, Kazumasa Hirata

    JOURNAL OF BIOSCIENCE AND BIOENGINEERING　Vol. 112　No. 5　p. 462-468　2011/11　Research paper (scientific journal)

  76. Isolation and partial characterization of the Chlamydomonas reinhardtii gamma-glutamyl kinase

    Keita Miyoshi, Hideyuki Matsuura, Takao Kumon, Keita Matsuda, Tomoaki Yoshikawa, Takeshi Bamba, Kazuo Harada, Kazumasa Hirata

    JOURNAL OF BIOSCIENCE AND BIOENGINEERING　Vol. 112　No. 1　p. 75-78　2011/07　Research paper (scientific journal)

  77. Molecular Cloning and Partial Characterization of a Peroxidase Gene Expressed in the Roots of Portulaca oleracea cv., One Potentially Useful in the Remediation of Phenolic Pollutants

    Takeshi Matsui, Yuki Nomura, Mai Takano, Sofue Imai, Hideki Nakayama, Hitoshi Miyasaka, Hiroshi Okuhata, Satoshi Tanaka, Hideyuki Matsuura, Kazuo Harada, Takeshi Bamba, Kazumasa Hirata, Ko Kato

    BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY　Vol. 75　No. 5　p. 882-890　2011/05　Research paper (scientific journal)

  78. Metabolomics-based systematic prediction of yeast lifespan and its application for semi-rational screening of ageing-related mutants

    Ryo Yoshida, Takayuki Tamura, Chika Takaoka, Kazuo Harada, Akio Kobayashi, Yukio Mukai, Eiichiro Fukusaki

    AGING CELL　Vol. 9　No. 4　p. 616-625　2010/08　Research paper (scientific journal)

  79. AtNUDX6, an ADP-Ribose/NADH Pyrophosphohydrolase in Arabidopsis, Positively Regulates NPR1-Dependent Salicylic Acid Signaling

    Kazuya Ishikawa, Kazuya Yoshimura, Kazuo Harada, Eiichiro Fukusaki, Takahisa Ogawa, Masahiro Tamoi, Shigeru Shigeoka

    PLANT PHYSIOLOGY　Vol. 152　No. 4　p. 2000-2012　2010/04　Research paper (scientific journal)

  80. Synthesis of Anti-Tumor Dimeric Indole Alkaloids in Catharanthus roseus Was Promoted by Irradiation with Near-Ultraviolet Light at Low Temperature

    Mamiko Asano, Kazuo Harada, Tomoaki Yoshikawa, Takeshi Bamba, Kazumasa Hirata

    BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY　Vol. 74　No. 2　p. 386-389　2010/02　Research paper (scientific journal)

  81. Comparative analysis of a CFo ATP synthase subunit II homologue derived from marine and fresh-water algae

    Yoshito Suda, Tomoaki Yoshikawa, Yuko Okuda, Mei Tsunemoto, Yuri Matsuda, Satoshi Tanaka, Kazunori Ikeda, Hitoshi Miyasaka, Kazuo Harada, Takeshi Bamba, Kazumasa Hirata

    JOURNAL OF BIOSCIENCE AND BIOENGINEERING　Vol. 108　No. 5　p. 365-368　2009/11　Research paper (scientific journal)

  82. Modulation of the Poly(ADP-ribosyl)ation Reaction via the Arabidopsis ADP-Ribose/NADH Pyrophosphohydrolase, AtNUDX7, Is Involved in the Response to Oxidative Stress

    Kazuya Ishikawa, Takahisa Ogawa, Eisuke Hirosue, Yasumune Nakayama, Kazuo Harada, Eiichiro Fukusaki, Kazuya Yoshimura, Shigeru Shigeoka

    PLANT PHYSIOLOGY　Vol. 151　No. 2　p. 741-754　2009/10　Research paper (scientific journal)

  83. Dimensionality reduction for metabolome data using PCA, PLS, OPLS, and RFDA with differential penalties to latent variables

    Hiroyuki Yamamoto, Hideki Yamaji, Yuichiro Abe, Kazuo Harada, Danang Waluyo, Eiichiro Fukusaki, Akihiko Kondo, Hiromu Ohno, Hideki Fukuda

    CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS　Vol. 98　No. 2　p. 136-142　2009/10　Research paper (scientific journal)

  84. Comprehensive metabolite profiling of phyA phyB phyC triple mutants to reveal their associated metabolic phenotype in rice leaves

    Kanokwan Jumtee, Atsushi Okazawa, Kazuo Harada, Eiichiro Fukusaki, Makoto Takano, Akio Kobayashi

    JOURNAL OF BIOSCIENCE AND BIOENGINEERING　Vol. 108　No. 2　p. 151-159　2009/08　Research paper (scientific journal)

  85. Extracellular phycoerythrin-like protein released by freshwater cyanobacteria Oscillatoria and Scytonema sp.

    Karseno, Kazuo Harada, Takeshi Bamba, Susilaningsih Dwi, Aparat Mahakhant, Tomoaki Yoshikawa, Kazumasa Hirata

    BIOTECHNOLOGY LETTERS　Vol. 31　No. 7　p. 999-1003　2009/07　Research paper (scientific journal)

  86. Isolation and characterization of a novel antistress gene from Chlamydomonas sp W80

    Yoshito Suda, Tomoaki Yoshikawa, Yuko Okuda, Mei Tsunemoto, Satoshi Tanaka, Kazunori Ikeda, Hitoshi Miyasaka, Masanori Watanabe, Ken Sasaki, Kazuo Harada, Takeshi Bamba, Kazumasa Hirata

    JOURNAL OF BIOSCIENCE AND BIOENGINEERING　Vol. 107　No. 4　p. 352-354　2009/04　Research paper (scientific journal)

  87. Transcriptional and metabolic response in yeast Saccharomyces cerevisiae cells during polyethylene glycol-dependent transformation

    Shigeyuki Kawal, Tuan Anh Phan, Emil Kono, Kazuo Harada, Chlhiro Okai, Eilchlro Fukusaki, Kousaku Murata

    JOURNAL OF BASIC MICROBIOLOGY　Vol. 49　No. 1　p. 73-81　2009/02　Research paper (scientific journal)

  88. Phytochelatins inhibit the metal-induced aggregation of alpha-crystallin

    Yasuhisa Hori, Tomoaki Yoshikawa, Naoki Tsuji, Takeshi Bamba, Yoshikazu Aso, Motonori Kudou, Yoshiki Uchida, Masahiro Takagi, Kazuo Harada, Kazumasa Hirata

    JOURNAL OF BIOSCIENCE AND BIOENGINEERING　Vol. 107　No. 2　p. 173-176　2009/02　Research paper (scientific journal)

  89. Overexpression of an ADP-ribose pyrophosphatase, AtNUDX2, confers enhanced tolerance to oxidative stress in Arabidopsis plants

    Takahisa Ogawa, Kazuya Ishikawa, Kazuo Harada, Eiichiro Fukusaki, Kazuya Yoshimura, Shigeru Shigeoka

    PLANT JOURNAL　Vol. 57　No. 2　p. 289-301　2009/01　Research paper (scientific journal)

  90. High-Throughput Technique for Comprehensive Analysis of Japanese Green Tea Quality Assessment Using Ultra-performance Liquid Chromatography with Time-of-Flight Mass Spectrometry (UPLC/TOF MS)

    Wipawee Pongsuwan, Takeshi Bamba, Kazuo Harada, Tsutomu Yonetani, Akio Kobayashi, Eiichiro Fukusaki

    JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY　Vol. 56　No. 22　p. 10705-10708　2008/11　Research paper (scientific journal)

  91. Time-course metabolic profiling in Arabidopsis thaliana cell cultures after salt stress treatment

    Jae Kwang Kim, Takeshi Bamba, Kazuo Harada, Eiichiro Fukusaki, Akio Kobayashi

    JOURNAL OF EXPERIMENTAL BOTANY　Vol. 58　No. 3　p. 415-424　2007/02　Research paper (scientific journal)

  92. In vivo N-15-enrichment of metabolites in Arabidopsis cultured cell T87 and its application to metabolomics

    Kazuo Harada, Ei-Ichiro Fulcusaki, Takeshi Bamba, Akio Kobayashi

    CONCEPTS IN PLANT METABOLOMICS　p. 287-+　2007　Research paper (international conference proceedings)

  93. Single cell-based analysis of Torenia petal pigments by a combination of ArF excimer laser micro sampling and nano-high performance liquid chromatography (HPLC)-mass spectrometry

    Shin'ichiro Kajiyama, Kazuo Harada, Eiichiro Fukusaki, Akio Kobayashi

    JOURNAL OF BIOSCIENCE AND BIOENGINEERING　Vol. 102　No. 6　p. 575-578　2006/12　Research paper (scientific journal)

  94. A novel crude oil emulsifier excreted in the culture supernatant of a marine bacterium, Myroides sp strain SM1

    S Maneerat, T Bamba, K Harada, A Kobayashi, H Yamada, F Kawai

    APPLIED MICROBIOLOGY AND BIOTECHNOLOGY　Vol. 70　No. 2　p. 254-259　2006/03　Research paper (scientific journal)

  95. Size exclusion chromatography of standard polystyrenes with a wide range of molecular weight up to 7.45 x 10(6) on monolithic silica capillary columns

    Koichi Ute, Saori Yoshida, Tatsuki Kitayama, Takeshi Bamba, Kazuo Harada, Eiichiro Fukusaki, Akio Kobayashi, Norio Ishizuka, Hiroyoshi Minakuchi, Kazuki Nakanishi

    POLYMER JOURNAL　Vol. 38　No. 11　p. 1194-1197　2006　Research paper (scientific journal)

  96. Stable isotope dilution-based accurate comparative quantification of nitrogen-containing metabolites in Arabidopsis thaliana T87 cells using in vivo N-15-isotope enrichment

    JK Kim, K Harada, T Bamba, E Fukusaki, A Kobayashi

    BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY　Vol. 69　No. 7　p. 1331-1340　2005/07　Research paper (scientific journal)

  97. An isotope effect on the comparative quantification of flavonoids by means of methylation-based stable isotope dilution coupled with capillary liquid chromatography/mass spectrometry

    EI Fukusaki, K Harada, T Bamba, A Kobayashi

    JOURNAL OF BIOSCIENCE AND BIOENGINEERING　Vol. 99　No. 1　p. 75-77　2005/01　Research paper (scientific journal)

Misc. 68

  1. 火災死等のシアンガス吸入時の血中シアン濃度の生理学的薬物速度論解析によるシミュレーション

    原田和生, 原田和生, 青木佑馬, 邉見和就, 徳川友梨, 坂橋優治, 東阪和馬, 東阪和馬, 宮下洋平, 杉本香奈, 片田竜一, 松本博志

    日本法医学会学術全国集会講演要旨集　Vol. 105th　2021

  2. Current situation and challenges of a regulatory concept of pharmacokinetics focusing on microbiome

    庄真喜子, 橘敬祐, 原田和生, 平田收正, 堤康央, 國澤純, 近藤昌夫

    腸内細菌学雑誌　Vol. 35　No. 2　2021

  3. バルベルト緑内障インプラント挿入術後に発症したバリウム誘導性中毒性前眼部症候群

    松下 賢治, 濱野 結貴, 原田 和生, 東阪 和馬, 馬場 耕一, 河嶋 瑠美, 橋田 徳康, 佐藤 茂, 松本 博志, 西田 幸二

    日本眼科学会雑誌　Vol. 124　No. 臨増　p. 216-216　2020/03

    Publisher: (公財)日本眼科学会

  4. ベトナムの豚肉から分離したmcr-3を有するコリスチン耐性大腸菌の解析

    山口貴弘, 河原隆二, 照屋志帆乃, 原田和生, 元岡大祐, 中村昇太, 中山達哉, 山本容正, 平田收正

    日本細菌学雑誌(Web)　Vol. 73　No. 1　2018

  5. ベトナムの環境における残留抗菌剤について

    原田 和生

    日本防菌防黴学会誌　Vol. 46　p. 461-464　2018　Article, review, commentary, editorial, etc. (scientific journal)

  6. ベトナムにおける抗菌性物質の環境水中残留実態

    原田 和生

    薬学雑誌　Vol. 138　p. 271-275　2018　Article, review, commentary, editorial, etc. (scientific journal)

  7. 13C安定同位体希釈に基づく新規代謝ターンオーバー解析システムの提案

    傳寳雄大, 中山泰宗, 原田和生, 馬場健史, 福崎英一郎

    日本農芸化学会大会講演要旨集(Web)　Vol. 2013　2013/03/05

  8. ベトナムにおける食肉中の動物用医薬品汚染実態について

    山口貴弘, 起橋雅浩, 原田和生, NGUYEN Duc Thinh, NGUYEN Do Phuc, 梶村計志, 久米田裕子, 平田收正, VU Trong Thien, 山本容正

    日本食品衛生学会学術講演会講演要旨集　Vol. 106th　2013

  9. 2Ha02 Production of nojirimycin, an inhibitor of parasitic weed germination, by Streptomyces ficellus

    Kurono Yurika, Nagasawa Saya, Oda Tomoka, Matsuura Hideyuki, Higashikubo Ryo, Wakabayashi Takatoshi, Yoshimoto Chizuru, Nomura Saki, Muranaka Satoru, Sugimoto Yukihiro, Okazawa Atsushi, Harada Kazuo, Hirata Kazumasa

    Vol. 63　p. 166-166　2011

    Publisher: 日本生物工学会

  10. 微生物共生系を利用した廃バイオマスの再資源化(<特集>地球環境と地域環境保全のための光合成微生物)

    原田 和生, 平田 收正

    生物工学会誌 : seibutsu-kogaku kaishi　Vol. 89　No. 3　p. 124-127　2011

    Publisher: 日本生物工学会

  11. Profiling of primary metabolite by means of capillary electrophoresis-mass spectrometry and its application for plant science

    Kazuo Harada, Eiichiro Fukusaki

    PLANT BIOTECHNOLOGY　Vol. 26　No. 1　p. 47-52　2009/03　Book review, literature introduction, etc.

  12. 「代謝ターンオーバー解析とバイオマス改変の応用」

    蓮沼誠久, 原田和生, 福崎英一郎

    第二世代バイオ燃料の開発と応用展開 (シーエムシー出版)　Vol. 121-130　2009

  13. 「CE/MSを用いた陰イオン性代謝産物の定量」 低温科学 第67巻 光合成研究法

    北海道大学 低温科学研究所　Vol. 163-168　2009

  14. 「安定同位体標識を利用した動的代謝プロファイリング」 低温科学 第67巻 光合成研究法

    北海道大学 低温科学研究所　Vol. 169-174　2009

  15. 13CO2を用いた同位体標識による葉内代謝物質のターンオーバー解析

    蓮沼誠久, 原田和生, 三宅親弘, 福崎英一郎

    生化学　2008

  16. 1A10-1 Development of anionic metabolite profiling using capillary electrophoresis/mass spectrometry with sulfonated capillary

    HARADA Kazuo, OHYAMA Yoko, TABUSHI Tetsuya, KOBAYASHI Akio, FUKUSAKI Eiichiro

    Vol. 19　p. 39-39　2007

    Publisher: 日本生物工学会

  17. 1A09-3 Metabolomic analysis of Catharanthus roseus with Methyl jasmonate treatment

    TABUSHI Tetsuya, HARADA Kazuo, KOBAYASHI Akio, FUKUSAKI Eiichiro

    Vol. 19　p. 39-39　2007

    Publisher: 日本生物工学会

  18. Metabolome analysis for metabolic responses of Catharanthus roseus against methyl jasmonate

    Kazuo Harada, Tetsuya Tabushi, Eiichiro Fukusaki, Akio Kobayashi

    PLANT AND CELL PHYSIOLOGY　Vol. 48　p. S258-S258　2007　Research paper, summary (international conference)

  19. 植物メタボロミクス技術の新展開

    福崎英一郎, 原田和生

    バイオサイエンスとインダストリー　Vol. 65　p. 8-14　2007

  20. 2B12-1 Development of metabolic profiling for anionic metabolites using capillary electrophoresis / mass spectrometry (CE/MS)

    HARADA Kazuo, FUKUSAKI Eiichiro, KOBAYASHI Akio

    Vol. 18　p. 30-30　2006

    Publisher: 日本生物工学会

  21. 61.Development of capillary electrophoresis-electrospray-tandem mass spectrometry (CE-ESI-MS/MS) using combination of polarity reversion and electroosmotic flow for anionic metabolite profiling

    Harada Kazuo, Fukusaki Eiichiro, Kobayashi Akio

    The Janapese Society for Chemical Regulation of Plants, Abstract　Vol. 41　No. 0　p. 76-76　2006

    Publisher: The Janapese Society for Chemical Regulation of Plants

  22. 脂肪肝モデルマウス由来脂質ナノディスクを用いたCYP/CPRの薬物代謝解析

    前田峻作, 山下沢, 芳賀優弥, 東阪和馬, 東阪和馬, 原田和生, 原田和生, 堤康央, 堤康央, 辻野博文, 辻野博文

    次世代を担う若手のためのフィジカル・ファーマフォーラム講演要旨集　Vol. 20th　2023

  23. 全エクソーム解析結果に見る心臓突然死症例の解剖所見と遺伝学的特徴の解明

    宮下洋平, 坂橋優治, 高橋真樹子, 望月薫, 磯部悠, 東阪和馬, 杉本香奈, 原田和生, 片田竜一, 松本博志

    日本法医学会学術全国集会講演要旨集　Vol. 105th　2021

  24. 脳梗塞後のトレッドミル運動による脳浮腫軽減の分子機構

    杉本香奈, 郷野里奈, 村田幸咲, 楊志斌, 原田悌志, 宮下洋平, 東阪和馬, 原田和生, 片田竜一, 松本博志

    日本法医学会学術全国集会講演要旨集　Vol. 105th　2021

  25. 脳梗塞後の脳浮腫形成にもたらす梗塞巣集積マクロファージの種類とその役割

    杉本香奈, 村田幸咲, 楊志斌, 郷野里奈, 原田悌志, 宮下洋平, 東阪和馬, 原田和生, 片田竜一, 松本博志

    日本法医学雑誌　Vol. 74　No. 1　2020

  26. 脳梗塞後の脳浮腫形成にもたらす活性化microglia/macrophagesの役割

    村田幸咲, 杉本香奈, 楊志斌, 郷野里奈, 平田雄一郎, 宮下洋平, 東阪和馬, 原田和生, 片田竜一, 松本博志

    日本法医学雑誌　Vol. 74　No. 2　2020

  27. 運転中に発症した心疾患事例の検討

    楊志斌, 片田竜一, 杉本香奈, 村田幸咲, 郷野里奈, 望月薫, 高橋真樹子, 藤本秀子, 宮下洋平, 東阪和馬, 原田和生, 松本博志

    日本法医学雑誌　Vol. 74　No. 2　2020

  28. 脳梗塞後の脳浮腫形成にもたらす梗塞巣集積マクロファージの種類とその役割

    杉本香奈, 村田幸咲, 郷野里奈, 楊志斌, 原田和生, 原田悌志, 宮下洋平, 東阪和馬, 片田竜一, 田中潤也, 松本博志

    脳循環代謝(Web)　Vol. 32　No. 1　2020

  29. 全エクソームおよびRNAシークエンスを用いた突然死の死亡機序の解明

    宮下洋平, 高橋真樹子, 望月薫, 中間健太郎, 東阪和馬, 杉本香奈, 原田和生, 片田竜一, 松本博志

    日本法医学雑誌　Vol. 73　No. 1　2019

  30. 心臓突然死症例における遺伝学的背景の解明

    有田一翔, 宮下洋平, 高橋真樹子, 中間健太郎, 東阪和馬, 杉本香奈, 原田和生, 片田竜一, 松本博志

    日本法医学雑誌　Vol. 73　No. 2　2019

  31. 全エクソームシークエンスを用いた心臓突然死疾患データベースの構築および突然死関連遺伝子の新規探索

    宮下洋平, 磯部悠, 坂橋優治, 加納直, 高橋真樹子, 東阪和馬, 杉本香奈, 原田和生, 片田竜一, 松本博志

    日本人類遺伝学会大会プログラム・抄録集　Vol. 64th　2019

  32. 低体温死におけるWischnewski斑形成の機序解明

    楊志斌, 杉本香奈, 村田幸咲, 平田雄一郎, 鎌倉悠宇, 宮下洋平, 東阪和馬, 原田和生, 片田竜一, 松本博志

    日本法医学雑誌　Vol. 73　No. 2　2019

  33. ベトナム・ホーチミンの食品から分離したコリスチン耐性大腸菌の解析

    山口貴弘, 山口貴弘, 河原隆二, 原田和生, 原田和生, NGUYEN Phuc Do, DANG Chinh Van, 久米田裕子, 山本容正, 山本容正, 平田收正, 平田收正

    日本細菌学雑誌(Web)　Vol. 72　No. 1　2017

  34. 無細胞反応系を用いた抗菌剤検出のための紙基板バイオセンサーの開発

    氏家和紀, 松浦秀幸, THI My Duyen Tran, 原田和生, 平田收正

    日本生物工学会大会講演要旨集　Vol. 69th　2017

  35. 組換え葉酸合成酵素を用いた紙基板サルファ剤発光センサーの開発

    氏家和紀, 松浦秀幸, DUYEN Tran Thi My, 原田和生, 平田收正

    日本農芸化学会中四国支部講演会講演要旨集(Web)　Vol. 49th　2017

  36. タンパク質合成阻害作用を持つ抗菌性物質検出のための紙を基盤とする比色センサーの開発

    氏家和紀, DUYEN Tran Thi My, 松浦秀幸, 村岡未彩, 原田和生, 平田收正

    日本分析化学会年会講演要旨集　Vol. 65th　2016

  37. ベトナム・ホーチミンにおける魚類中合成抗菌剤の残留実態

    小西良昌, 内田耕太郎, 山口貴弘, 起橋雅浩, 原田和生, 久米田裕子, DO Mai Hong Ngoc, BUI Long Thi, NGUYEN Thinh Duc, NGYUEN Phuc Do, LE Ninh Hoang, CHINH Dang Van, 平田收正, 山本容正

    環境化学討論会要旨集(CD-ROM)　Vol. 24th　2015

  38. ベトナムにおける食品中の残留抗菌薬実態調査およびモニタリングシステム構築に向けた取り組み

    山口貴弘, 起橋雅浩, 原田和生, 小西良昌, 内田耕太郎, MAI Do Ngoc Hoang, LONG Bui Thi, THINH Nguyen Duc, PHUC Nguyen Do, HUONG Thien Bui Dang, HA Phan Bich, 梶村計志, 久米田裕子, 平田收正, CHINH Dang Van, 山本容正

    日本食品衛生学会学術講演会講演要旨集　Vol. 110th　2015

  39. 3P-145 Immobilization of endocrine disrupting chemicals-metabolizing enzyme from Portulaca oleracea cv.

    Matsushima Kazuki, Kaneda Hirokazu, Amino Shinya, Harada Kazuo, Matsuura Hideyuki, Hirata Kazumasa

    Vol. 66　p. 231-231　2014

    Publisher: 日本生物工学会

  40. 1P-113 Production of nojirimycin, an inhibitor of parasitic weed germination, by Streptomyces ficellus

    Suzuoka Maki, Harada Kazuo, Kurono Yurika, Nagasawa Saya, Matsuura Hideyuki, Okazawa Atsushi, Hirata Kazumasa

    Vol. 66　p. 45-45　2014

    Publisher: 日本生物工学会

  41. ベトナムにおける食品中の動物用医薬品汚染実態調査

    山口貴弘, 起橋雅浩, 原田和生, 河原隆二, 小西良昌, 内田耕太郎, 浅山恵, 割鞘美苗, NGUYEN Duc Thinh, NGUYEN Do Phuc, 梶村計志, 久米田裕子, 平田收正, LE Hoang Ninh, 山本容正

    環境化学討論会要旨集(CD-ROM)　Vol. 23rd　2014

  42. ベトナムで検出された食肉中のスルファクロジンについて

    起橋雅浩, 山口貴弘, 原田和生, NGUYEN Duc Thinh, NGUYEN Do Phuc, 梶村計志, 久米田裕子, 平田收正, VU Trong Thien, 山本容正

    日本食品衛生学会学術講演会講演要旨集　Vol. 106th　2013

  43. 膵β細胞におけるインクレチン/cAMPシグナルとグルコース代謝の相互作用

    小倉雅仁, 小倉雅仁, 岩崎真宏, 吾甫尓江艾尼, 南幸太郎, 柴崎忠雄, 中山泰宗, 原田和生, 馬場健史, 福崎英一郎, 清野進

    糖尿病　Vol. 55　No. Supplement 1　2012/04/25

  44. 土壌中のセシウムの挙動に関する研究-その2:セシウムの吸着-

    吉田有輝, 桑原裕紀, 関谷一輝, 五十嵐亨, 野村直希, 三島史人, 秋山庸子, 原田和生, 平田收正, 西嶋茂宏

    日本放射線安全管理学会学術大会講演予稿集　Vol. 11th　2012

  45. 土壌中のセシウムの挙動に関する研究-その1:セシウムの脱離-

    桑原裕紀, 関谷一輝, 吉田有輝, 五十嵐亨, 野村直希, 三島史人, 秋山庸子, 原田和生, 平田收正, 西嶋茂宏

    日本放射線安全管理学会学術大会講演予稿集　Vol. 11th　2012

  46. 2Bp08 Metabolomic analysis of polyhydroxyalkanoate-producing Ralstonia eutropha

    Fukui Toshiaki, Chou Kenta, Harada Kazuo, Nakayama Yasumune, Orita Izumi, Bamba Takeshi, Nakamura Satoshi, Fukusaki Eiichiro

    日本生物工学会大会講演要旨集　Vol. 63　p. 122-122　2011

    Publisher: 日本生物工学会

  47. 膵β細胞内グルコース代謝とcAMPシグナルとの相互作用

    岩崎真宏, 南幸太郎, 柴崎忠雄, 中山泰宗, 原田和生, 馬場健史, 三木隆司, 宮崎純一, 福崎英一郎, 清野進

    糖尿病　Vol. 53　No. Supplement 1　2010/04/25

  48. 55. Enhancement of sensitivity to MeJA of Arabidopsis thaliana by green leaf volatiles

    Hirao Toshihiro, Okazawa Atsushi, Harada Kazuo, Kobayashi Akio, Muranaka Toshiya, Hirata Kazumasa

    The Janapese Society for Chemical Regulation of Plants, Abstract　Vol. 45　p. 72-72　2010

    Publisher: The Janapese Society for Chemical Regulation of Plants

  49. 2P-1080 Evaluation of Chlamydomonas reinhardtii Proline synthase by site-directed mutagenesis

    MIYOSHI Keita, KUMON Takao, MATSUURA Hideyuki, MATSUDA Keita, YAMADA Kazuma, HARADA Kazuo, HIRATA Kazumasa

    Vol. 22　p. 28-28　2010

    Publisher: 日本生物工学会

  50. 植物による環境保全・浄化のポテンシャル 環境ホルモンを分解する植物―環境浄花―

    平田收正, 原田和生, 奥畑博史, 宮坂均

    Bio Ind　Vol. 26　No. 11　p. 15-20　2009/11/12

  51. Production of useful compounds from surplus biomass by microbial consortia

    Journal of environmental biotechnology　Vol. 9　No. 1　p. 11-16　2009/07

    Publisher: 環境バイオテクノロジー学会

  52. 3S13a05 Recycling of waste biomass by using microbe symbiosis

    HARADA Kazuo, HIRATA Kazumasa

    Vol. 21　p. 279-279　2009

    Publisher: 日本生物工学会

  53. “代謝調節機構解析に基づく細胞機能制御基盤技術”研究領域 植物細胞インタクト液胞を用いたポストゲノム解析と液胞膜エンジニアリングによる液胞代謝動態の解析

    大西美輪, 姉川彩, 原田和生, 及川彰, 中山泰宗, 佐々木亮介, 七條千津子, 深城英弘, 杉山裕子, HATCHER Patrick G, 福崎英一郎, MARTINOIA Enrico, 青木考, 三村徹郎

    代謝調節機構解析に基づく細胞機能制御基盤技術研究領域 第2回公開シンポジウム講演要旨集 平成21年　2009

  54. “代謝調節機構解析に基づく細胞機能制御基盤技術”研究領域 メタボローム解析による膵β細胞インスリン分泌機構の解明

    岩崎真宏, 南幸太郎, 柴崎忠雄, 中山泰宗, 馬場健史, 原田和生, 福崎英一郎, 清野進

    代謝調節機構解析に基づく細胞機能制御基盤技術研究領域 第2回公開シンポジウム講演要旨集 平成21年　2009

  55. Post-genome analysis of plant intact vacuole

    Ohnishi Miwa, Hatcher Patrick G, Fukusaki Eiichiro, Mimura Tetsuro, Harada Kazuo, Oikawa Akira, Anegawa Aya, Oda Yoshihisa, Nakayama Yasumune, Shichijo Chizuko, Fukaki Hidehiro, Sugiyama Yuko

    Plant and Cell Physiology Supplement　Vol. 2009　No. 0　p. 305-305　2009

    Publisher: The Japanese Society of Plant Physiologists

  56. Pressure-Assisted Capillary Electrophoresis Mass Spectrometry Using Combination of Polarity Reversion and Electroosmotic Flow for Metabolomics Anion Analysis

    原田 和生, 福崎 英一郎, 小林 昭雄

    生物工学会誌 : seibutsu-kogaku kaishi　Vol. 86　No. 1　p. 16-16　2008/01/25

    Publisher: 日本生物工学会

  57. 2Ca05 High-throughput, high-resolution analysis of hydrophobic metabolites by supercritical fluid chromatography/mass spectrometry

    MATSUBARA Atsuki, ISHIDA Hiroki, HARADA Kazuo, HIRATA Kazumasa, FUKUSAKI Ei-ichiro, BAMBA Takeshi

    Vol. 20　p. 98-98　2008

    Publisher: 日本生物工学会

  58. 2Ba02 Function analysis of stress responder in microalgae : analysis of biosynthetic pathway of abscisic acid in Chlamydomonas reinhardtii

    ISHIDA Hiroki, MATSUBARA Atsuki, BABA Takeshi, FUKUSAKI Eiichiro, HARADA Kazuo, HIRATA Kazumasa

    Vol. 20　p. 79-79　2008

    Publisher: 日本生物工学会

  59. New Technical Stream of Plant Metabolomics

    FUKUSAKI Eiichiro, HARADA Kazuo

    Bioscience & industry　Vol. 65　No. 10　p. 498-504　2007/10/01

    Publisher: バイオインダストリー協会

  60. 1A09-1 Metabolomics of yeast longevity mutants

    YOSHIDA Ryo, HARADA Kazuo, HAYASHI Shunnsuke, TAKAOKA Chika, TAMURA Takayuki, MUKAI Yukio, KOBAYASHI Akio, FUKUSAKI Eiichiro

    Vol. 19　p. 39-39　2007

    Publisher: 日本生物工学会

  61. 2H12-1 Analysis of transcripts using ESI-MS(I) : investigation of ionization condition

    KAJIWARA Shin'ichi, RIHARA Yoshiyuki, IZUMI Yoshihiro, HARADA Kazuo, FUKUSAKI Ei-ichiro, KOBAYASHI Akio

    日本生物工学会大会講演要旨集　Vol. 17　p. 221-221　2005/09/25

    Publisher: 公益社団法人日本生物工学会

  62. 2F09-1 Metabolome analysis of salt stress response in plant cell culture system

    FUKUSAKI Eiichiro, KIM JaeKwang, BABA Takeshi, HARADA Kazuo, KOBAYASHI Akio

    Vol. 17　p. 174-174　2005

    Publisher: 日本生物工学会

  63. 2F09-2 A novel capillary electrophoresis mass spectrometry (CE/MS) for metabolome analysis

    HARADA Kazuo, FUKUSAKI Eiichiro, KOBAYASHI Akio

    Vol. 17　p. 174-174　2005

    Publisher: 日本生物工学会

  64. 3B11-4 In vivo ^<15>N-enrichment of metabolites in Arabidopsis cultured cell T87 and its application for metabolomics

    HARADA Kazuo, FUKUSAKI Ei-ichiro, BAMBA Takeshi, KOBAYASHI Akio

    Vol. 16　p. 131-131　2004

    Publisher: 日本生物工学会

  65. 68. In vivo ^<15>N-enrichment of metabolites in plant cultured cell and its application for metabolomics

    Fukusaki Eiichiro, Harada Kazuo, Bamba Takeshi, Kobayashi Akio

    The Janapese Society for Chemical Regulation of Plants, Abstract　Vol. 39　No. 0　p. 89-89　2004

    Publisher: The Janapese Society for Chemical Regulation of Plants

  66. 77. Proteomic analysis of Arabidopsis seeds imbibed deuterium oxide

    Onishi Ryohei, Okazawa Atsushi, Harada Kazuo, Fukusaki Eiichiro, Kobayashi Akio

    The Janapese Society for Chemical Regulation of Plants, Abstract　Vol. 39　No. 0　p. 98-98　2004

    Publisher: The Janapese Society for Chemical Regulation of Plants

  67. Application of UV pulsed laser micro beam to plant cells (VI) : One cell analysis of petal pigments using laser microsampling

    Kajiyama Shinichiro, Watabe Tatsuya, Harada Kazuo, Fukusaki Eiichiro, Kobayashi Akio

    日本生物工学会大会講演要旨集　Vol. 15　p. 119-119　2003/08/25

    Publisher: 公益社団法人日本生物工学会

  68. 47(P-9) Single cell analysis of plant metabolites using LASER micro sampling

    Kobayashi A, Kajiyama S, Watabe T, Harada K, Fukusaki E

    Symposium on the Chemistry of Natural Products, symposium papers　Vol. 45　No. 0　p. 275-280　2003

    Publisher: Symposium on the Chemistry of Natural Products Steering Committee

Publications 2

  1. メタボロミクスの先端技術と応用（福崎英一郎監修） 第15章 in vivo同位体標識による網羅的代謝物ターンオーバー解析

    シーエムシー出版　2008

  2. メタボロミクスの先端技術と応用（福崎英一郎監修） 第3章CE/MSによるアニオン性代謝産物解析システムの開発

    シーエムシー出版　2008

Presentations 5

  1. 機能性食品の品質評価，品質管理に資する低分子測定とメタボロミクス

    原田和生

    日本薬学会 第144年会 シンポジウム S22 心身のセルフケアのための素材開発と実用化 ～健康長寿を目指して～　2024/03/29

  2. Antibiotic residue in environmental water and fresh food in Vietnam

    HARADA Kazuo

    79th FIP World Congress of Pharmacy and Pharmaceutical Sciences, Abu Dhabi, United Arab Emirates　2019/09/23

  3. メタボロミクスによる生薬・漢方薬エキスの生物活性との相関解析

    原田 和生

    日本薬学会 第138年会 シンポジウムS05　2018/03/26

  4. ベトナムにおける抗菌性物質の環境水中残留実態

    原田 和生

    日本薬学会 第137年会 シンポジウムS46　2017/03/27

  5. メタボローム解析を用いた生薬の品質評価

    原田 和生

    薬剤師漢方セミナー　2015/07/12

Works 4

  1. グローバルな食糧確保に貢献する寄生雑草制御技術の開発

    2011 -

  2. グローバルな食糧確保に貢献する寄生雑草制御技術の開発

    2010 -

  3. 亜熱帯微生物資源を活用する次世代物造りバイオ技術の構築

    2009 -

  4. Next-generation bioproduction platform leveraging subtropical microbial bioresources

    2009 -

Institutional Repository 5

Content Published in the University of Osaka Institutional Repository (OUKA)

  1. Correlation between the metabolic profile of Nelumbo Seed, a component of Seishinrenshiin, and its inhibitory activity on bladder smooth muscle contraction

    Harada Kazuo, Fukuda Yuki, Ohkubo Takahiro, Sugaya Kimio, Osaki Yukihiko

    Journal of Natural Medicines　2025/03/19

  2. Photocatalytic Multiple Deuteration of Polyethylene Glycol Derivatives Using Deuterium Oxide

    Ogasahara Riku, Mae Miyu, Matsuura Keisuke, Yoshimura Sota, Ishimoto Takayoshi, Udagawa Taro, Harada Kazuo, Fujioka Hiroyoshi, Kamiya Mako, Asada Rio, Uchiyama Hiromasa, Tozuka Yuichi, Akai Shuji, Sawama Yoshinari

    Chemistry - A European Journal　2025/01/07

  3. Molecular mechanism of cerebral edema improvement via IL-1RA released from the stroke-unaffected hindlimb by treadmill exercise after cerebral infarction in rats

    Gono Rina, Sugimoto Kana, Yang Chihpin, Murata Yukie, Nomura Reiko, Shirazaki Mai, Harada Kazuo, Harada Teiji, Miyashita Yohei, Higashisaka Kazuma, Katada Ryuichi, Matsumoto Hiroshi

    Journal of Cerebral Blood Flow and Metabolism　Vol. 43　No. 5　p. 812-827　2023/05/01

  4. Carbon(sp2)-carbon(sp3) Bond-forming Cross-coupling Reactions Using Sulfur-Modified Au-Supported Nickel Nanoparticle Catalyst

    Ohta Ryousuke, Shio Yasunori, Akiyama Toshiki, Yamada Makito, Shimoda Shuhei, Harada Kazuo, Sako Makoto, Hasegawa Junya, Arisawa Mitsuhiro

    Asian Journal of Organic Chemistry　Vol. 11　No. 9　2022/06/27

  5. 代謝産物プロファイリングに資するキャピラリー電気泳動/質量分析法の開発に関する研究

    原田 和生