顔写真

PHOTO

Kajihara Yasuhiro
梶原　康宏
Kajihara Yasuhiro
梶原　康宏
Institutional repository
Graduate School of Science　Department of Chemistry，Professor

keyword Organic Chemistry, Carbohydrate Chemistry, Protein Chemistry，Organic Chemistry

Institutional repository

Research History 5

  1. 2009/04 - Present
    Osaka University　Graduate School of Science　Professor

  2. 2007/04 - 2009/03
    Yokohama City University　Graduate School of Integrated Science　Professor

  3. 2001/04 - 2007/03
    Yokohama City University　Graduate School of Integrated Science　Associate Professor

  4. 1995/06 - 2001/03
    Yokohama City University　Faculty of Science　Assistant Professor

  5. 1993/04 - 1995/05
    Japan Tobacco Inc　Life Science Research laboratory　PostDoc

Education 3

  1. Tokyo Institute of Technology　Interdisciplinary Graduate School of Science and Engineering　Life Chemistry

    1990/04 - 1993/03

  2. Kanagawa University　Graduate School of Engineering.　Chemistry

    1988/04 - 1990/03

  3. Kanagawa University　Faculty of Engineering

    1984/04 - 1988/03

Committee Memberships 1

  1. 日本糖質学会　理事　Academic society

    2009/07 - Present

Professional Memberships 3

  1. 日本糖質学会

  2. アメリカ化学会

  3. 日本化学会

Research Areas 2

  1. Life sciences / Bioorganic chemistry / Carbohydrate chemistry

  2. Nanotechnology/Materials / Structural/physical organic chemistry / Carbohydrate chemistry

Awards 3

  1. Roy L Whistler Award

    KAJIHARA Yasuhiro　:International Carbohydrate Organization　2020/07

  2. Award for creative research of Japanese chemical society

    KAJIHARA Yasuhiro　Chemical Society of Japan　2014/03

  3. Encouragement Awards of Japan Society of Carbohydrate Research

    KAJIHARA Yasuhiro　Japanese Society of carbohydrate Research　2002/08

Papers 108

  1. Rapid synthesis of glycosylated insulins by flow-based peptide synthesis

    Yuta Maki, Surin K. Mong, Chaitra Chandrashekar, Briony E. Forbes, Mohammed Akhter Hossain, Shintaro Yamaguchi, Colin M. Fadzen, Yasuhiro Kajihara, Bradley L. Pentelute

    Chemical Science　2025　Research paper (scientific journal)

    Publisher: Royal Society of Chemistry (RSC)

  2. Harnessing Free Sulfate Groups in Glycosylation Reactions.

    Yuta Maki, Akihiro Manbo, Abe Junpei, Hiroki Nobutou, Kohtaro Hirao, Ryo Okamoto, Masayuki Izumi, Shusuke Yamanaka, Mitsutaka Okumura, Yasuhiro Kajihara

    Angewandte Chemie (International ed. in English)　2024/11/14　Research paper (scientific journal)

  3. Uncovering a Latent Bioactive Interleukin‐6 Glycoform

    Yasuhiro Kajihara, Yanbo Liu, Yuta Maki, Ryo Okamoto, Ayano Satoh, Yasuto Todokoro, Yurie Kanemitsu, Keito Otani

    Angewandte Chemie International Edition　2024/08/05　Research paper (scientific journal)

    Publisher: Wiley

  4. Isopeptide bond formation mediated by δ-selenolysine for chemical ubiquitination

    Tatsunari Akiyama, Yusuke Tanaka, Ryo Okamoto, Yasuhiro Kajihara, Masayuki Izumi

    Frontiers in Chemistry　Vol. 11　2023/11/21　Research paper (scientific journal)

    Publisher: Frontiers Media SA

  5. Semisynthesis of homogeneous misfolded glycoprotein interleukin-8.

    Yugoviandi P Mamahit, Yuta Maki, Ryo Okamoto, Yasuhiro Kajihara

    Carbohydrate research　Vol. 531　p. 108847-108847　2023/09　Research paper (scientific journal)

  6. Rapid Chemical Synthesis of Serine Protease Inhibitor Kazal-type 13 (SPINK13) Glycoform by a Combined Method with Glycan Insertion Strategy and Fast-Flow Fmoc SPPS.

    Kota Nomura, Ryo Okamoto, Yuta Maki, Ayumu Hayashibara, Toshifumi Takao, Tomoya Fukuoka, Eiji Miyoshi, Bradley L Pentelute, Yasuhiro Kajihara

    Chemistry (Weinheim an der Bergstrasse, Germany)　Vol. 29　No. 42　2023/07/26　Research paper (scientific journal)

  7. Recent advances on the synthesis of N-linked glycoprotein for the elucidation of glycan functions

    Yanbo Liu, Kota Nomura, Junpei Abe, Yasuhiro Kajihara

    Current Opinion in Chemical Biology　Vol. 73　p. 102263-102263　2023/04　Research paper (scientific journal)

    Publisher: Elsevier BV

  8. Regulating Antifreeze Activity through Water: Latent Functions of the Sugars of Antifreeze Glycoprotein Revealed by Total Chemical Synthesis.

    Ryo Okamoto, Ryo Orii, Hiroyuki Shibata, Yuta Maki, Sakae Tsuda, Yasuhiro Kajihara

    Chemistry (Weinheim an der Bergstrasse, Germany)　Vol. 29　No. 21　2023/01/31　Research paper (scientific journal)

  9. Convergent synthesis of proteins using peptide-aminothiazoline

    Ryo Okamoto, Hiroyuki Shibata, Takahiro Yatsuzuka, Takuya Hanao, Yuta Maki, Kazuya Kabayama, Ayane Miura, Koichi Fukase, Yasuhiro Kajihara

    Chemical Communications　2023　Research paper (scientific journal)

    Publisher: Royal Society of Chemistry (RSC)

  10. Squaryl group-modified UDP analogs as inhibitors of the endoplasmic reticulum-resident folding sensor enzyme UGGT

    Junpei Abe, Yoichi Takeda, Takashi Kikuma, Yasuhiko Kizuka, Hiroyuki Kajiura, Yasuhiro Kajihara, Yukishige Ito

    Chemical Communications　2023　Research paper (scientific journal)

    Publisher: Royal Society of Chemistry (RSC)

  11. Isolation and characterization of high-mannose type glycans containing five or six mannose residues from hen egg yolk

    Yuta Maki, Yuiko Otani, Ryo Okamoto, Masayuki Izumi, Yasuhiro Kajihara

    Carbohydrate Research　Vol. 521　p. 108680-108680　2022/11　Research paper (scientific journal)

    Publisher: Elsevier BV

  12. Design and Synthesis of Glycosylated Cholera Toxin B Subunit as a Tracer of Glycoprotein Trafficking in Organelles of Living Cells

    Yuta Maki, Kazuki Kawata, Yanbo Liu, Kang‐Ying Goo, Ryo Okamoto, Yasuhiro Kajihara, Ayano Satoh

    Chemistry – A European Journal　2022/05/23　Research paper (scientific journal)

    Publisher: Wiley

  13. Semisynthesis of a Homogeneous Glycoprotein Using Chemical Transformation of Peptides to Thioester Surrogates

    Ryo Okamoto, Kento Iritani, Yoko Amazaki, Donglin Zhao, Chaitra Chandrashekar, Yuta Maki, Yurie Kanemitsu, Tomoka Kaino, Yasuhiro Kajihara

    The Journal of Organic Chemistry　Vol. 87　No. 1　p. 114-124　2022/01/07　Research paper (scientific journal)

    Publisher: American Chemical Society (ACS)

  14. Synthesis of homogeneous glycoproteins with diverse N-glycans

    Kota Nomura, Yanbo Liu, Yasuhiro Kajihara

    Advances in Carbohydrate Chemistry and Biochemistry　2022　Part of collection (book)

    Publisher: Elsevier

  15. Optimizing the Semisynthesis towards glycosylated interferon-β-polypeptide by utilizing bacterial protein expression and chemical modification

    Yie Kie Chong, Chaitra Chandrashekar, Donglin Zhao, Yuta Maki, Ryo Okamoto, Yasuhiro Kajihara

    Organic & Biomolecular Chemistry　Vol. 20　No. 9　p. 1907-1915　2022　Research paper (scientific journal)

    Publisher: Royal Society of Chemistry (RSC)

  16. Purified EDEM3 or EDEM1 alone produces determinant oligosaccharide structures from M8B in mammalian glycoprotein ERAD.

    Ginto George, Satoshi Ninagawa, Hirokazu Yagi, Jun-Ichi Furukawa, Noritaka Hashii, Akiko Ishii-Watabe, Ying Deng, Kazutoshi Matsushita, Tokiro Ishikawa, Yugoviandi P Mamahit, Yuta Maki, Yasuhiro Kajihara, Koichi Kato, Tetsuya Okada, Kazutoshi Mori

    eLife　Vol. 10　2021/10/26　Research paper (scientific journal)

  17. Glycoprotein Semisynthesis by Chemical Insertion of Glycosyl Asparagine Using a Bifunctional Thioacid-Mediated Strategy

    Kota Nomura, Yuta Maki, Ryo Okamoto, Ayano Satoh, Yasuhiro Kajihara

    Journal of the American Chemical Society　Vol. 143　No. 27　p. 10157-10167　2021/06/30　Research paper (scientific journal)

    Publisher: American Chemical Society (ACS)

  18. Synthesis of the glycoprotein having an N-linked complex type oligosaccharide

    Yasuhiro Kajihara, Ryo Okamoto

    2021

    Publisher: Japan Consortium for Glycobiology and Glycotechnology

  19. Studies in glycopeptide synthesis

    Yasuhiro Kajihara, Rie Nishikawa, Yuta Maki, Ryo Okamoto

    Arkivoc　Vol. 2021　No. 4　p. 230-240　2020/12/11　Research paper (scientific journal)

    Publisher: ARKAT USA, Inc.

  20. Chemical Synthesis of an Erythropoietin Glycoform Having a Triantennary N-Glycan: Significant Change of Biological Activity of Glycoprotein by Addition of a Small Molecular Weight Trisaccharide

    Yuta Maki, Ryo Okamoto, Masayuki Izumi, Yasuhiro Kajihara

    Journal of the American Chemical Society　2020/11/24　Research paper (scientific journal)

    Publisher: American Chemical Society (ACS)

  21. Studies for Elucidation of Oligosaccharide Functions of Glycoproteins

    Yuta Maki, Ryo Okamoto, Masumi Murakami, Yasuhiro Kajihara

    Journal of Synthetic Organic Chemistry, Japan　Vol. 78　No. 11　p. 1021-1038　2020/11/01　Research paper (scientific journal)

    Publisher: The Society of Synthetic Organic Chemistry, Japan

  22. Chemical Synthesis Based Approach to Glycoprotein Functions in the Endoplasmic Reticulum.

    Yukishige Ito, Yasuhiro Kajihara, Yoichi Takeda

    Chemistry (Weinheim an der Bergstrasse, Germany)　2020/10/26　Research paper (scientific journal)

  23. Chemical Synthesis of Ubiquitinated High-Mannose-Type N-Glycoprotein CCL1 in Different Folding States.

    Masayuki Izumi, Hiroyuki Araki, Mamiko Tominaga, Ryo Okamoto, Yasuhiro Kajihara

    The Journal of organic chemistry　Vol. 85　No. 24　p. 16024-16034　2020/10/07　Research paper (scientific journal)

  24. Acceleration and Deceleration Factors on the Hydrolysis Reaction of 4,6-O-Benzylidene Acetal Group.

    Yuta Maki, Kota Nomura, Ryo Okamoto, Masayuki Izumi, Yasuhisa Mizutani, Yasuhiro Kajihara

    The Journal of organic chemistry　2020/05/12　Research paper (scientific journal)

  25. Identification of the epitope of 10-7G glycan antibody to recognize cancer-associated haptoglobin.

    Koichi Morishita, Yuta Maki, Shinji Takamatsu, Nami Ito, Sayaka Koda, Kei Motooka, Yoshihiro Kamada, Yasuhiro Kajihara, Eiji Miyoshi

    Analytical biochemistry　Vol. 593　p. 113588-113588　2020/03/15

  26. A Chemoselective Peptide Bond Formation by Amino Thioacid Coupling

    Okamoto Ryo, Nomura Kota, Maki Yuta, Kajihara Yasuhiro

    CHEMISTRY LETTERS　Vol. 48　No. 11　p. 1391-1393　2019/11　Research paper (scientific journal)

  27. N,N-Dimethylaminoxy Carbonyl, a Polar Protecting Group for Efficient Peptide Synthesis.

    Okamoto R, Ono E, Izumi M, Kajihara Y

    Frontiers in chemistry　Vol. 7　2019/03/28

  28. Chemical and enzymatic synthesis and production of glycans

    Yukishige Ito, Toshiki Nokami, Yasuhiro Kajihara, Ichiro Matsuo, Hideharu Ishida, Hiromune Ando, Koichi Fukase, Jun Ichi Tamura, Toshiyuki Inazu

    Glycoscience: Basic Science to Applications: Insights from the Japan Consortium for Glycobiology and Glycotechnology (JCGG)　p. 65-86　2019/01/01　Part of collection (book)

  29. Regioselective α-peptide bond formation through the oxidation of amino thioacids

    Ryo Okamoto, Takuya Haraguchi, Kota Nomura, Yuta Maki, Masayuki Izumi, Yasuhiro Kajihara

    Biochemistry　Vol. 58　p. 1672-1678　2019　Research paper (scientific journal)

  30. Chemical Modification of the N Termini of Unprotected Peptides for Semisynthesis of Modified Proteins by Utilizing a Hydrophilic Protecting Group

    C. Chandrashekar, R.Okamoto, M. Izumi, Y. Kajihara

    Chem. Eur. J　Vol. 25　p. 10197-10203　2019　Research paper (scientific journal)

  31. Total Chemical Synthesis of a Non-Fibrillating Human Glycoinsulin,Mohammed

    Akhter Hossain, Ryo Okamoto, John A. Karas, Praveen Praveen, Mengjie Liu, Briony E Forbes, John D. Wade, Yasuhiro Kajihara

    J. Am. Chem. Soc.　2019　Research paper (scientific journal)

  32. Semisynthesis of Complex-Type Biantennary Oligosaccharides Containing Lactosamine Repeating Units from a Biantennary Oligosaccharide Isolated from a Natural Source

    Yuta Maki, Takanori Mima, Ryo Okamoto, Masayuki Izumi, Yasuhiro Kajihara

    Journal of Organic Chemistry　Vol. 83　No. 1　p. 443-451　2018/01/05　Research paper (scientific journal)

    Publisher: American Chemical Society

  33. Monitoring of glycoprotein quality control system with a series of chemically synthesized homogeneous native and misfolded glycoproteins

    Tatsuto Kiuchi, Masayuki Izumi, Yuki Mukogawa, Arisa Shimada, Ryo Okamoto, Akira Seko, Masafumi Sakono, Yoichi Takeda, Yukishige Ito, Yasuhiro Kajihara

    J. Am. Chem. Soc.　Vol. 140　No. 50　p. 17499-17507　2018　Research paper (scientific journal)

  34. Recent advances in the chemical synthesis of N-linked glycoproteins.

    Carlo Unverzagt, Yasuhiro Kajihara

    Curr. Opin. Chem. Biol　Vol. 46　p. 130-137　2018　Research paper (scientific journal)

  35. Substrate Recognition of Glycoprotein Folding Sensor UGGT Analyzed by Site-Specifically N-15-Labeled Glycopeptide and Small Glycopeptide Library Prepared by Parallel Native Chemical Ligation

    Masayuki Izumi, Rie Kuruma, Ryo Okamoto, Akira Seko, Yukishige Ito, Yasuhiro Kajihara

    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY　Vol. 139　No. 33　p. 11421-11426　2017/08　Research paper (scientific journal)

  36. Total Synthesis of O-GalNAcylated Antifreeze Glycoprotein using the Switchable Reactivity of Peptidyl-N-pivaloylguanidine

    Ryo Orii, Noriko Sakamoto, Daichi Fukami, Sakae Tsuda, Masayuki Izumi, Yasuhiro Kajihara, Ryo Okamoto

    CHEMISTRY-A EUROPEAN JOURNAL　Vol. 23　No. 39　p. 9253-9257　2017/07　Research paper (scientific journal)

  37. Chemical Synthesis of Glycoproteins with the Specific Installation of Gradient-Enriched N-15-Labeled Amino Acids for Getting Insights into Glycoprotein Behavior

    Nguyen Minh Hien, Masayuki Izumi, Hajime Sato, Ryo Okamoto, Yasuhiro Kajihara

    CHEMISTRY-A EUROPEAN JOURNAL　Vol. 23　No. 27　p. 6579-6585　2017/05　Research paper (scientific journal)

  38. Direct assay for endo-alpha-mannosidase substrate preference on correctly folded and misfolded model glycoproteins

    Simone Dedola, Masayuki Izumi, Yutaka Makimura, Akira Seko, Akiko Kanamori, Yoichi Takeda, Yukishige Ito, Yasuhiro Kajihara

    CARBOHYDRATE RESEARCH　Vol. 434　p. 94-98　2016/11　Research paper (scientific journal)

  39. Chemical synthesis of homogeneous antifreeze glycoprotein having uniform GalNAc modification and its antifreeze activity

    Ryo Okamoto, Ryo Orii, Masayuki Izumi, Daichi Fukami, Sakae Tsuda, Yasuhiro Kajihara

    PROTEIN SCIENCE　Vol. 25　p. 65-65　2016/10

  40. Effects of domain composition on catalytic activity of human UDP-glucose:glycoprotein glucosyltransferases

    Yoichi Takeda, Akira Seko, Kohki Fujikawa, Masayuki Izumi, Yasuhiro Kajihara, Yukishige Ito

    GLYCOBIOLOGY　Vol. 26　No. 9　p. 999-1006　2016/09　Research paper (scientific journal)

  41. D-Amino Acid Scan of Two Small Proteins

    Mark D. Simon, Yuta Maki, Alexander A. Vinogradov, Chi Zhang, Hongtao Yu, Yu-Shan Lin, Yasuhiro Kajihara, Bradley L. Pentelute

    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY　Vol. 138　No. 37　p. 12099-12111　2016/09　Research paper (scientific journal)

  42. Evaluation of the Effect of Post-Translational Modification Toward Protein Structure: Chemical Synthesis of Glycosyl Crambins Having Either a High Mannose-Type or a Complex-Type Oligosaccharide

    Simone Dedola, Masayuki Izumi, Yutaka Makimura, Yukishige Ito, Yasuhiro Kajihara

    BIOPOLYMERS　Vol. 106　No. 4　p. 446-452　2016/07　Research paper (scientific journal)

  43. An efficient solid-phase synthesis of peptidyl-N-acetylguanidines for use in native chemical ligation

    Ryo Okamoto, Madoka Isoe, Masayuki Izumi, Yasuhiro Kajihara

    JOURNAL OF PEPTIDE SCIENCE　Vol. 22　No. 5　p. 343-351　2016/05　Research paper (scientific journal)

  44. Synthesis of Glc(1)Man(9)-Glycoprotein Probes by a Misfolding/Enzymatic Glucosylation/Misfolding Sequence

    Masayuki Izumi, Yukiho Oka, Ryo Okamoto, Akira Seko, Yoichi Takeda, Yukishige Ito, Yasuhiro Kajihara

    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION　Vol. 55　No. 12　p. 3968-3971　2016/03　Research paper (scientific journal)

  45. Semisynthesis of Intact Complex-Type Triantennary Oligosaccharides from a Biantennary Oligosaccharide Isolated from a Natural Source by Selective Chemical and Enzymatic Glycosylation

    Yuta Maki, Ryo Okamoto, Masayuki Izumi, Takefumi Murase, Yasuhiro Kajihara

    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY　Vol. 138　No. 10　p. 3461-3468　2016/03　Research paper (scientific journal)

  46. Synthesis of misfolded glycoprotein dimers through native chemical ligation of a dimeric peptide thioester

    Masayuki Izumi, Shinji Komaki, Ryo Okamoto, Akira Seko, Yoichi Takeda, Yukishige Ito, Yasuhiro Kajihara

    ORGANIC & BIOMOLECULAR CHEMISTRY　Vol. 14　No. 25　p. 6088-6094　2016　Research paper (scientific journal)

  47. Chemical synthesis of erythropoietin glycoforms for insights into the relationship between glycosylation pattern and bioactivity

    Masumi Murakami, Tatsuto Kiuchi, Mika Nishihara, Katsunari Tezuka, Ryo Okamoto, Masayuki Izumi, Yasuhiro Kajihara

    Science Advances　Vol. 2　No. 1　2016/01/01　Research paper (scientific journal)

    Publisher: American Association for the Advancement of Science

  48. Synthesis of Glc1Man9-glycoprotein probes by a unique misfolding/enzymatic glucosylation/intentional misfolding approach

    M. Izumi, Y. Oka, R. Okamoto, A. Seko, Y. Takeda, Y. Ito, Y. Kajihara

    Angew. Chem. Int. Ed　Vol. 128　p. 4036-4039　2016　Research paper (scientific journal)

  49. Efficient Synthesis of L-galactose from D-galactose

    Ryo Orii, Masayuki Izumi, Yasuhiro Kajihara, Ryo Okamoto

    JOURNAL OF CARBOHYDRATE CHEMISTRY　Vol. 34　No. 9　p. 560-566　2015/11　Research paper (scientific journal)

  50. Synthesis of D,L-amino acid derivatives bearing a thiol at the beta-position and their enzymatic optical resolution

    Yasuhito Morishita, Tomoka Kaino, Ryo Okamoto, Masayuki Izumi, Yasuhiro Kajihara

    TETRAHEDRON LETTERS　Vol. 56　No. 47　p. 6565-6568　2015/11　Research paper (scientific journal)

  51. Chemical synthesis of homogeneous glycoproteins

    Masayuki Izumi, Ryo Okamoto, Yasuhiro Kajihara

    Glycoscience: Biology and Medicine　p. 313-321　2015/01/01　Part of collection (book)

    Publisher: Springer Japan

  52. Efficient synthesis of polypeptide-alpha-thioester by the method combining polypeptide expression and chemical activation for the semi-synthesis of interferon-gamma having oligosaccharides

    Yasuhiro Kajihara, Yurie Kanemitsu, Mika Nishihara, Ryo Okamoto, Masayuki Izumi

    JOURNAL OF PEPTIDE SCIENCE　Vol. 20　No. 12　p. 958-963　2014/12　Research paper (scientific journal)

  53. Chemical Synthesis of a Synthetic Analogue of the Sialic Acid-Binding Lectin Siglec-7

    Masayuki Izumi, Akihisa Otsuki, Mika Nishihara, Ryo Okamoto, Yasuhiro Kajihara

    CHEMBIOCHEM　Vol. 15　No. 17　p. 2503-2507　2014/11　Research paper (scientific journal)

  54. Semisynthesis of a Post-Translationally Modified Protein by Using Chemical Cleavage and Activation of an Expressed Fusion Polypeptide

    Ryo Okamoto, Motoharu Kimura, Takeshi Ishimizu, Masayuki Izumi, Yasuhiro Kajihara

    CHEMISTRY-A EUROPEAN JOURNAL　Vol. 20　No. 33　p. 10425-10430　2014/08　Research paper (scientific journal)

  55. Total Chemical Synthesis and Biological Activities of Glycosylated and Non-Glycosylated Forms of the Chemokines CCL1 and Ser-CCL1

    Ryo Okamoto, Kalyaneswar Mandal, Morris Ling, Andrew D. Luster, Yasuhiro Kajihara, Stephen B. H. Kent

    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION　Vol. 53　No. 20　p. 5188-5193　2014/05　Research paper (scientific journal)

  56. (Quasi-)Racemic X-ray Structures of Glycosylated and Non-Glycosylated Forms of the Chemokine Ser-CCL1 Prepared by Total Chemical Synthesis

    Ryo Okamoto, Kalyaneswar Mandal, Michael R. Sawaya, Yasuhiro Kajihara, Todd O. Yeates, Stephen B. H. Kent

    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION　Vol. 53　No. 20　p. 5194-5198　2014/05　Research paper (scientific journal)

  57. Both isoforms of human UDP-glucose:glycoprotein glucosyltransferase are enzymatically active

    Yoichi Takeda, Akira Seko, Masakazu Hachisu, Shusaku Daikoku, Masayuki Izumi, Akihiko Koizumi, Kohki Fujikawa, Yasuhiro Kajihara, Yukishige Ito

    GLYCOBIOLOGY　Vol. 24　No. 4　p. 344-350　2014/04　Research paper (scientific journal)

  58. Folding of Synthetic Homogeneous Glycoproteins in the Presence of a Glycoprotein Folding Sensor Enzyme

    Simone Dedola, Masayuki Izumi, Yutaka Makimura, Akira Seko, Akiko Kanamori, Masafumi Sakono, Yukishige Ito, Yasuhiro Kajihara

    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION　Vol. 53　No. 11　p. 2883-2887　2014/03　Research paper (scientific journal)

  59. Safe and efficient Boc-SPPS for the synthesis of glycopeptide-alpha-thioesters

    Masayuki Izumi, Masumi Murakami, Ryo Okamoto, Yasuhiro Kajihara

    JOURNAL OF PEPTIDE SCIENCE　Vol. 20　No. 2　p. 98-101　2014/02　Research paper (scientific journal)

  60. Chemical assembly of N-glycoproteins: a refined toolbox to address a ubiquitous posttranslational modification

    Carlo Unverzagt, Yasuhiro Kajihara

    CHEMICAL SOCIETY REVIEWS　Vol. 42　No. 10　p. 4408-4420　2013　Research paper (scientific journal)

  61. Efficient synthesis of glycopeptide-alpha-thioesters with a high-mannose type oligosaccharide by means of tert-Boc-solid phase peptide synthesis

    Yutaka Makimura, Tatsuto Kiuchi, Masayuki Izumi, Simone Dedola, Yukishige Ito, Yasuhiro Kajihara

    CARBOHYDRATE RESEARCH　Vol. 364　p. 41-48　2012/12　Research paper (scientific journal)

  62. Homogeneous Human Complex-Type Oligosaccharides in Correctly Folded Intact Glycoproteins: Evaluation of Oligosaccharide Influence On Protein Folding, Stability, and Conformational Properties

    Yasuhiro Kajihara, Yasutaka Tanabe, Shun Sasaoka, Ryo Okamoto

    CHEMISTRY-A EUROPEAN JOURNAL　Vol. 18　No. 19　p. 5944-5953　2012/05　Research paper (scientific journal)

  63. Chemical Synthesis of Intentionally Misfolded Homogeneous Glycoprotein: A Unique Approach for the Study of Glycoprotein Quality Control

    Masayuki Izumi, Yutaka Makimura, Simone Dedola, Akira Seko, Akiko Kanamori, Masafumi Sakono, Yukishige Ito, Yasuhiro Kajihara

    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY　Vol. 134　No. 17　p. 7238-7241　2012/05　Research paper (scientific journal)

  64. Chemical Synthesis of Homogeneous Human Glycosyl-interferon-beta That Exhibits Potent Antitumor Activity in Vivo

    Izumi Sakamoto, Katsunari Tezuka, Kazuhiro Fukae, Kazuyuki Ishii, Keisuke Taduru, Masatoshi Maeda, Masaki Ouchi, Kenta Yoshida, Yuri Nambu, Jun Igarashi, Naohiro Hayashi, Takashi Tsuji, Yasuhiro Kajihara

    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY　Vol. 134　No. 12　p. 5428-5431　2012/03　Research paper (scientific journal)

  65. A Synthetic Approach to a Peptide alpha-Thioester from an Unprotected Peptide through Cleavage and Activation of a Specific Peptide Bond by N-Acetylguanidine

    Ryo Okamoto, Keiko Morooka, Yasuhiro Kajihara

    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION　Vol. 51　No. 1　p. 191-196　2012　Research paper (scientific journal)

  66. Chemical Synthesis of an Erythropoietin Glycoform Containing a Complex-type Disialyloligosaccharide

    Masumi Murakami, Ryo Okamoto, Masayuki Izumi, Yasuhiro Kajihara

    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION　Vol. 51　No. 15　p. 3567-3572　2012　Research paper (scientific journal)

  67. A seven-transmembrane receptor that mediates avoidance response to dihydrocaffeic acid, a water-soluble repellent in Caenorhabditis elegans

    Reina Aoki, Tatsurou Yagami, Hiroyuki Sasakura, Ken Ichi Ogura, Yasuhiro Kajihara, Masakazu Ibi, Takeaki Miyamae, Fumio Nakamura, Taro Asakura, Yoshikatsu Kanai, Yoshimi Misu, Yuichi Iino, Marina Ezcurra, William R. Schafer, Ikue Mori, Yoshio Goshima

    Journal of Neuroscience　Vol. 31　No. 46　p. 16603-16610　2011/11/16　Research paper (scientific journal)

  68. 40 The Precise Chemical Glycoprotein Synthesis Assigned by a Unique X-ray Crystallography(Oral Presentation)

    Okamoto R., Mandal Kalyaneswar, Sawaya Michael, Yeates Todd O., Kent Stephen B.H., Kajihara Y.

    Symposium on the Chemistry of Natural Products, symposium papers　No. 53　p. 235-240　2011/09/02

    Publisher: Symposium on the chemistry of natural products

  69. Unique Self-Anhydride Formation in the Degradation of Cytidine-5 '-monophosphosialic Acid (CMP-Neu5Ac) and Cytidine-5 '-diphosphosialic Acid (CDP-Neu5Ac) and its Application in CMP-sialic Acid Analogue Synthesis

    Yasuhiro Kajihara, Sachiko Nishigaki, Daisuke Hanzawa, Go Nakanishi, Ryo Okamoto, Naoki Yamamoto

    CHEMISTRY-A EUROPEAN JOURNAL　Vol. 17　No. 27　p. 7645-7655　2011/06　Research paper (scientific journal)

  70. Synthesis of bioactive homogenous glycoprotein analogue

    Vol. 61　No. 1　p. 47-61　2011

    Publisher:

  71. Semisynthesis of Erythropoietin Analog Having Three Oligosaccharides

    Kiriko Hirano, Masayuki Izumi, Derek Macmillan, Katsunari Tezuka, Takashi Tsuji, Yasuhiro Kajihara

    JOURNAL OF CARBOHYDRATE CHEMISTRY　Vol. 30　No. 4-6　p. 306-319　2011　Research paper (scientific journal)

  72. Expanding the Scope of Native Chemical Ligation in Glycopeptide Synthesis

    Ryo Okamoto, Masayuki Izumi, Yasuhiro Kajihara

    INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS　Vol. 16　No. 3　p. 191-198　2010/09　Research paper (scientific journal)

  73. Unique cleavage of 2-acetamido-2-deoxy-D-glucose from the reducing end of biantennary complex type oligosaccharides

    Takefumi Murase, Yasuhiro Kajihara

    CARBOHYDRATE RESEARCH　Vol. 345　No. 12　p. 1702-1707　2010/08　Research paper (scientific journal)

  74. Synthesis of the glycosylated polypeptide chain of an inducible costimulator on T-cells

    Takefumi Murase, Yasuhiro Kajihara

    CARBOHYDRATE RESEARCH　Vol. 345　No. 10　p. 1324-1330　2010/07　Research paper (scientific journal)

  75. Total Synthesis of (-)-Tetrodotoxin from D-Glucose: A New Route to Multi-Functionalized Cyclitol Employing the Ferrier(II) Reaction toward (-)-Tetrodotoxin

    Shoji Akai, Hidehito Seki, Naoki Sugita, Tomokazu Kogure, Naoki Nishizawa, Katsuhiko Suzuki, Yutaka Nakamura, Yasuhiro Kajihara, Juji Yoshimura, Ken-ichi Sato

    BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN　Vol. 83　No. 3　p. 279-287　2010/03　Research paper (scientific journal)

  76. An alpha 2,3-Sialyltransferase from Photobacterium sp JT-ISH-224 Transfers N-Acetylneuraminic Acid to Both the O-2 and O-3' Hydroxyl Groups of Lactose

    Toshiki Mine, Hitomi Kajiwara, Takefumi Murase, Yasuhiro Kajihara, Takeshi Yamamoto

    JOURNAL OF CARBOHYDRATE CHEMISTRY　Vol. 29　No. 2　p. 51-60　2010　Research paper (scientific journal)

  77. SYNTHESIS OF GLYCOPEPTIDES

    Yasuhiro Kajihara, Ryo Okamoto, Naoki Yamamoto, Masayuki Izumi

    METHODS IN ENZYMOLOGY, VOL 478: GLYCOMICS　Vol. 478　p. 503-519　2010　Part of collection (book)

  78. Synthesis of Heavily Glycosylated Peptide Thioester

    Kiriko Hirano, Yasuhiro Kajihara

    JOURNAL OF CARBOHYDRATE CHEMISTRY　Vol. 29　No. 2　p. 84-91　2010　Research paper (scientific journal)

  79. Definitive evidence that a single N-glycan among three glycans on inducible costimulator is required for proper protein trafficking and ligand binding

    Naoki Kamei, Rie Fukui, Yoshiyuki Suzuki, Yasuhiro Kajihara, Mitsuhiro Kinoshita, Kazuaki Kakehi, Hironobu Hojo, Katsunari Tezuka, Takashi Tsuji

    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS　Vol. 391　No. 1　p. 557-563　2010/01　Research paper (scientific journal)

  80. Chemical Synthesis of Homogeneous Glycopeptides and Glycoproteins

    Yasuhiro Kajihara, Naoki Yamamoto, Ryo Okamoto, Kiriko Hirano, Takefumi Murase

    CHEMICAL RECORD　Vol. 10　No. 2　p. 80-100　2010　Research paper (scientific journal)

  81. Protein Cysteine Modifications: (2) Reactivity Specificity and Topics of Medicinal Chemistry and Protein Engineering

    N. Nagahara, T. Matsumura, R. Okamoto, Y. Kajihara

    CURRENT MEDICINAL CHEMISTRY　Vol. 16　No. 34　p. 4490-4501　2009/12

  82. Protein Cysteine Modifications: (1) Medicinal Chemistry for Proteomics

    N. Nagahara, T. Matsumura, R. Okamoto, Y. Kajihara

    CURRENT MEDICINAL CHEMISTRY　Vol. 16　No. 33　p. 4419-4444　2009/11

  83. Efficient and systematic synthesis of a small glycoconjugate library having human complex type oligosaccharides

    Takefumi Murase, Takashi Tsuji, Yasuhiro Kajihara

    CARBOHYDRATE RESEARCH　Vol. 344　No. 6　p. 762-770　2009/04　Research paper (scientific journal)

  84. Efficient Substitution Reaction from Cysteine to the Serine Residue of Glycosylated Polypeptide: Repetitive Peptide Segment Ligation Strategy and the Synthesis of Glycosylated Tetracontapeptide Having Acid Labile Sialyl-T-N Antigens

    Ryo Okamoto, Shingo Souma, Yasuhiro Kajihara

    JOURNAL OF ORGANIC CHEMISTRY　Vol. 74　No. 6　p. 2494-2501　2009/03　Research paper (scientific journal)

  85. Robust synthesis of N-linked branch-type oligosaccharides is going to uncover the function of oligosaccharides

    KAJIHARA Yasuhiro

    TIGG　Vol. 21　No. 117　p. 45-47　2009/01/31

    Publisher: FCCA(Forum: Carbohydrates Coming of Age)

  86. Design and Synthesis of a Homogeneous Erythropoietin Analogue with Two Human Complex-Type Sialyloligosaccharides: Combined Use of Chemical and Bacterial Protein Expression Methods

    Kiriko Hirano, Derek Macmillan, Katsunari Tezuka, Takashi Tsuji, Yasuhiro Kajihara

    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION　Vol. 48　No. 50　p. 9557-9560　2009　Research paper (scientific journal)

  87. 2D Selective-TOCSY-DQFCOSY and HSQC-TOCSY NMR experiments for assignment of a homogeneous asparagine-linked triantennary complex type undecasaccharide

    Hajime Sato, Kazuhiro Fukae, Yasuhiro Kajihara

    Carbohydrate Research　Vol. 343　No. 8　p. 1333-1345　2008/06/09　Research paper (scientific journal)

  88. Efficient synthesis of MUC4 sialylglycopeptide through the new sialylation using 5-acetamido-neuraminamide donors

    Ryo Okamoto, Shingo Souma, Yasuhiro Kajihara

    JOURNAL OF ORGANIC CHEMISTRY　Vol. 73　No. 9　p. 3460-3466　2008/05　Research paper (scientific journal)

  89. Chemical synthesis of a glycoprotein having an intact human complex-type sialyloligosaccharide under the Boc and Fmoc synthetic strategies

    Naoki Yamamoto, Yasutaka Tanabe, Ryo Okamoto, Philip E. Dawson, Yasuhiro Kajihara

    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY　Vol. 130　No. 2　p. 501-510　2008/01　Research paper (scientific journal)

  90. Uncovering a latent ligation site for glycopeptide synthesis

    Ryo Okamoto, Yasuhiro Kajihara

    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION　Vol. 47　No. 29　p. 5402-5406　2008　Research paper (scientific journal)

  91. Synthesis of CMP-9"-modified-sialic acids as donor substrate analogues for mammalian and bacterial sialyltransferases

    Yasuhiro Kajihara, Toshimi Kamitani, Reiko Sato, Naoki Kamei, Tatsuo Miyazaki, Ryo Okamoto, Thoru Sakakibara, Takashi Tsuji, Takeshi Yamamoto

    CARBOHYDRATE RESEARCH　Vol. 342　No. 12-13　p. 1680-1688　2007/09　Research paper (scientific journal)

  92. P-54 Chemical Synthesis of small glycoproteins having human complex type oligosaccharide

    Kajihara Yasuhiro, Okamoto Ryo, Sasaoka Shun, Tanabe Yasutaka

    Symposium on the Chemistry of Natural Products, symposium papers　No. 49　p. 637-642　2007/08/24

    Publisher: Symposium on the chemistry of natural products

  93. Solid-state O-17 NMR in biological solids: Efficient O-17 labeling of amino acids and peptides

    Kazuhiko Yamada, Toshio Yamazaki, Miwako Asanuma, Hiroshi Hirota, Naoki Yamamoto, Yasuhiro Kajihara

    CHEMISTRY LETTERS　Vol. 36　No. 1　p. 192-193　2007/01　Research paper (scientific journal)

  94. An approach for a synthesis of asparagine-linked sialylglycopeptides having intact and homogeneous complex-type undecadisialyloligosaccharides

    Naoki Yamamoto, Ayumi Takayanagi, Ayako Yoshino, Tohru Sakakibara, Yasuhiro Kajihara

    CHEMISTRY-A EUROPEAN JOURNAL　Vol. 13　No. 2　p. 613-625　2007　Research paper (scientific journal)

  95. Convenient synthesis of a sialylglycopeptide-thioester having an intact and homogeneous complex-type disialyl-oligosaccharide

    Yasuhiro Kajihara, Akiko Yoshihara, Kiriko Hirano, Naoki Yamamoto

    CARBOHYDRATE RESEARCH　Vol. 341　No. 10　p. 1333-1340　2006/07　Research paper (scientific journal)

  96. An improvement in the bending ability of a hinged trisaccharide with the assistance of a sugar-sugar interaction

    H Yuasa, T Izumi, N Mitsuhashi, Y Kajihara, H Hashimoto

    CHEMISTRY-A EUROPEAN JOURNAL　Vol. 11　No. 22　p. 6478-6490　2005/11　Research paper (scientific journal)

  97. Synthesis and evaluation of 5-thio-L-fucose-containing oligosaccharide

    M Izumi, O Tsuruta, Y Kajihara, S Yazawa, H Yuasa, H Hashimoto

    CHEMISTRY-A EUROPEAN JOURNAL　Vol. 11　No. 10　p. 3032-3038　2005/05　Research paper (scientific journal)

  98. An unambiguous assignment method by 2D selective-TOCSY-HSQC and selective-TOCSY-DQFCOSY and structural analysis by selective-TOCSY-NOESY experiments of a biantennary undecasaccharide

    Hajime Sato, Yasuhiro Kajihara

    Carbohydrate Research　Vol. 340　No. 3　p. 469-479　2005/02/28　Research paper (scientific journal)

  99. Synthesis of 2-[(2-pyridyl)amino]ethyl beta-D-lactosaminide and evaluation of its acceptor ability for sialyltransferase: a comparison with 4-methylumbelliferyl and dansyl beta-D-lactosaminide

    Y Kajihara, D Kamiyama, N Yamamoto, T Sakakibara, M Izumi, H Hashimoto

    CARBOHYDRATE RESEARCH　Vol. 339　No. 8　p. 1545-1550　2004/06　Research paper (scientific journal)

  100. Convenient synthesis of a glycopeptide analogue having a complex type disialyl-undecasaccharide

    Naoki Yamamoto, Tohru Sakakibara, Yasuhiro Kajihara

    Tetrahedron Letters　Vol. 45　No. 16　p. 3287-3290　2004/04/12　Research paper (scientific journal)

  101. Chemoenzymatic synthesis of diverse asparagine-linked alpha-(2,3)-sialyloligosaccharides

    K Fukae, N Yamamoto, Y Hatakeyama, Y Kajihara

    GLYCOCONJUGATE JOURNAL　Vol. 21　No. 5　p. 243-250　2004　Research paper (scientific journal)

  102. Sialylation of Oligosaccharide on a Protein by Chemoenzymatic Method

    KAJIHARA Yasuhiro

    J. Synth. Org. Chem. Jpn.　Vol. 58　No. 2　p. 138-146　2000/02/01

    Publisher: The Society of Synthetic Organic Chemistry, Japan

  103. Galactosyl transfer ability of beta-(1 -> 4)-galactosyltransferase toward 5a-carba-sugars

    Y Kajihara, H Hashimoto, S Ogawa

    CARBOHYDRATE RESEARCH　Vol. 323　No. 1-4　p. 44-48　2000/01　Research paper (scientific journal)

  104. Enzymatic synthesis of Kdn oligosaccharides by a bacterial alpha-(2 -> 6)-sialyltransferase

    Y Kajihara, S Akai, T Nakagawa, R Sato, T Ebata, H Kodama, K Sato

    CARBOHYDRATE RESEARCH　Vol. 315　No. 1-2　p. 137-141　1999/01　Research paper (scientific journal)

  105. Novel aspects of interaction between UDP-Gal and GlcNAc beta-1,4-galactosyltransferase: Transferability and remarkable inhibitory activity of UDP-(mono-O-methylated gal), UDP-Fuc and UDP-Man

    T Endo, Y Kajihara, H Kodama, H Hashimoto

    BIOORGANIC & MEDICINAL CHEMISTRY　Vol. 4　No. 11　p. 1939-1948　1996/11　Research paper (scientific journal)

  106. ENZYMATIC TRANSFER OF 6-MODIFIED D-GALACTOSYL RESIDUES - SYNTHESIS OF BIANTENNARY PENTA-SACCHARIDES AND HEPTA-SACCHARIDES HAVING 2 6-DEOXY-D-GALACTOSE RESIDUES AT THE NONREDUCING END AND EVALUATION OF 6-DEOXY-D-GALACTOSYL TRANSFER TO GLYCOPROTEIN USING BOVINE BETA-(1-]4)-GALACTOSYLTRANSFERASE AND UDP-6-DEOXY-D-GALACTOSE

    Y KAJIHARA, T ENDO, H OGASAWARA, H KODAMA, H HASHIMOTO

    CARBOHYDRATE RESEARCH　Vol. 269　No. 2　p. 273-294　1995/04　Research paper (scientific journal)

  107. SYNTHESIS OF UDP-6-DEOXY-D-GALACTOSES AND UDP-6-FLUORO-D-GALACTOSES AND THEIR ENZYMATIC GLYCOSYL TRANSFER TO MONOANTENNARY AND BIANTENNARY CARBOHYDRATE CHAINS

    H KODAMA, Y KAJIHARA, T ENDO, H HASHIMOTO

    TETRAHEDRON LETTERS　Vol. 34　No. 40　p. 6419-6422　1993/10　Research paper (scientific journal)

  108. METHYL-3-O-(2-ACETAMIDO-2-DEOXY-6-THIO-BETA-D-GLUCOPYRANOSYL)-BETA-D-GALACTOPYRANOSIDE - A SLOW REACTING ACCEPTOR-ANALOG WHICH INHIBITS GLYCOSYLATION BY UDP-D-GALACTOSE-N-ACETYL-D-GLUCOSAMINE-(1-]4)-BETA-D-GALACTOSYLTRANSFERASE

    Y KAJIHARA, H HASHIMOTO, H KODAMA

    CARBOHYDRATE RESEARCH　Vol. 229　No. 1　p. C5-C9　1992/05　Research paper (scientific journal)

Misc. 82

  1. Precise synthesis of homogeneous glycoproteins: Advancing functional analysis

    平尾宏太郎, 真木勇太, 梶原康宏

    実験医学　Vol. 43　No. 2　2025

  2. Insight into behavior and effect of a free sulfate group for glycosylation

    満保章泰, 真木勇太, 真木勇太, 阿部純平, 信藤紘樹, 岡本亮, 和泉雅之, 山中秀介, 奥村光隆, 梶原康宏, 梶原康宏

    日本糖質学会年会要旨集　Vol. 43rd　2024

  3. Revisiting the function of glycans on glycoproteins in protein-protein interaction

    岡本亮, 岡本亮, 真木勇太, 真木勇太, 佐藤あやの, 梶原康宏, 梶原康宏

    日本糖質学会年会要旨集　Vol. 41st　2022

  4. 糖タンパク質の細胞内逆行輸送の定量化

    佐藤あやの, 真木勇太, 川田一稀, 岡本亮, 梶原康宏

    日本生化学会大会(Web)　Vol. 95th　2022

  5. Glycopeptide synthesis for construction of quaternary structure of IgG antibody Fc region

    西川晴美, 上田南, 真木勇太, 真木勇太, 岡本亮, 岡本亮, 和泉雅之, 梶原康宏, 梶原康宏

    日本糖質学会年会要旨集　Vol. 41st　2022

  6. Chemical synthesis of glycosylated Cholera toxin B-subunit and its delivering into living cells

    真木勇太, 佐藤あやの, 川田一希, 岡本亮, 梶原康宏

    日本糖質学会年会要旨集　Vol. 40th　2021

  7. Homogeneous Glycoprotein Synthesis by Chemical Insertion of Glycan

    野村幸汰, 真木勇太, 真木勇太, 岡本亮, 岡本亮, 佐藤あやの, 梶原康宏, 梶原康宏

    日本糖質学会年会要旨集　Vol. 40th　2021

  8. Dynamic behavior of water molecules by hydration shells of glycans on proteins

    岡本亮, 岡本亮, 真木勇太, 真木勇太, 芝田大之, 佐藤あやの, 梶原康宏, 梶原康宏

    日本糖質学会年会要旨集　Vol. 40th　2021

  9. Synthetic Study of Fc Fragment of Human IgG Antibody for Elucidation of the Glycan Function in Folding Process

    西川晴美, 上田南, 真木勇太, 真木勇太, 岡本亮, 岡本亮, 和泉雅之, 梶原康宏, 梶原康宏

    日本化学会春季年会講演予稿集(Web)　Vol. 101st　2021

  10. Monitoring of glycoprotein quality control system in the presence of inhibitor of folding sensor enzyme

    齋藤泉, 大谷結子, 向川友紀, 山内美紀, 和泉雅之, 真木勇太, 真木勇太, 岡本亮, 岡本亮, 伊藤幸成, 梶原康宏, 梶原康宏

    日本化学会春季年会講演予稿集(Web)　Vol. 101st　2021

  11. Synthetic study of a complex-type sialyloligosaccharide containing a lactam structure

    森口達也, 松野剛, 真木勇太, 真木勇太, 岡本亮, 岡本亮, 和泉雅之, 梶原康宏, 梶原康宏

    日本化学会春季年会講演予稿集(Web)　Vol. 101st　2021

  12. Delivery of a synthetic Cholera Toxin B-subunit Bearing an Oligosaccharide to Golgi apparatus for Elucidation of biosynthetic pathway of Glycan-branch formation

    川田一稀, 真木勇太, 岡本亮, 梶原康宏, 吉井優也, 佐藤あやの

    日本化学会春季年会講演予稿集(CD-ROM)　Vol. 100th　2020

  13. Synthetic study of N-linked oligosaccharide with lactam structure

    森口達也, 松野剛, 真木勇太, 岡本亮, 和泉雅之, 梶原康宏

    日本糖質学会年会要旨集　Vol. 39th　2020

  14. Monitoring of Glycoprotein Quality Control System with UDP-5S-Glucose

    齋藤泉, 大谷結子, 向川友紀, 山内美紀, 和泉雅之, 真木勇太, 真木勇太, 岡本亮, 岡本亮, 伊藤幸成, 梶原康宏, 梶原康宏

    日本糖質学会年会要旨集　Vol. 39th　2020

  15. Kinetic parameters of chemically synthesized sialyltransferase

    島田有彩, 真木勇太, 岡本亮, 和泉雅之, 伊藤幸成, 梶原康宏

    日本化学会春季年会講演予稿集(CD-ROM)　Vol. 100th　2020

  16. Monitoring of Glycoprotein Quality Control System with UDP-5S-Glucose

    齋藤泉, 大谷結子, 向川友紀, 山内美紀, 和泉雅之, 真木勇太, 岡本亮, 伊藤幸成, 梶原康宏

    日本化学会春季年会講演予稿集(CD-ROM)　Vol. 100th　2020

  17. ラクタム構造を有するN結合型糖鎖の合成研究

    森口達也, 松野剛, 真木勇太, 岡本亮, 和泉雅之, 梶原康宏

    日本化学会春季年会講演予稿集(CD-ROM)　Vol. 99th　2019

  18. 13C標識UDP-Glcを利用した糖タンパク質品質管理機構の追跡

    大谷結子, 向川友紀, 山内美紀, 和泉雅之, 真木勇太, 岡本亮, 梶原康宏

    日本化学会春季年会講演予稿集(CD-ROM)　Vol. 99th　2019

  19. Boc固相合成法と大腸菌発現法を用いたFcフラグメントの合成と二量化に向けたフォールディングの条件検討

    上田南, 今田翔平, 真木勇太, 岡本亮, 和泉雅之, 梶原康宏

    日本化学会春季年会講演予稿集(CD-ROM)　Vol. 99th　2019

  20. 化学合成により調製した不凍糖タンパク質を用いたO-GalNAc残基の機能解明

    折井亮, 深見大地, 深見大地, 津田栄, 津田栄, 真木勇太, 和泉雅之, 梶原康宏, 岡本亮

    日本化学会春季年会講演予稿集(CD-ROM)　Vol. 99th　2019

  21. ペプチド固相合成に利用できるδ位に置換基を有するD-リジン誘導体の合成

    秋山龍成, 田中勇祐, 岡本亮, 梶原康宏, 和泉雅之

    日本化学会春季年会講演予稿集(CD-ROM)　Vol. 99th　2019

  22. シアル酸転移酵素の半合成と活性評価

    島田有彩, 真木勇太, 岡本亮, 和泉雅之, 伊藤幸成, 梶原康宏

    日本糖質学会年会要旨集　Vol. 38th　2019

  23. 質量分析を用いたフコース認識レクチンPhoSLとその変異体の糖鎖結合能解析

    和泉雅之, 橋本桂吾, 岡本亮, 梶原康宏

    日本糖質学会年会要旨集　Vol. 38th　2019

  24. UDP-[U-13C]-Glucoseを利用した糖タンパク質品質管理機構の追跡

    齋藤泉, 大谷結子, 向川友紀, 山内美紀, 和泉雅之, 真木勇太, 岡本亮, 伊藤幸成, 梶原康宏

    日本糖質学会年会要旨集　Vol. 38th　2019

  25. 三分枝複合型糖鎖を持つエリスロポエチンの合成とその生理活性評価

    真木勇太, 真木勇太, 岡本亮, 岡本亮, 和泉雅之, 梶原康宏, 梶原康宏

    日本糖質学会年会要旨集　Vol. 38th　2019

  26. Effects of N-Glycans on Glycoprotein Folding and Protein Dynamics.

    Amazaki Y, Nguyen HM, Okamoto R, Maki Y, Kajihara Y

    Advances in experimental medicine and biology　Vol. 1104　p. 1-19　2018/01/01

  27. ヒトUGGTの触媒活性に与えるドメインの解析

    武田陽一, 武田陽一, 今村有希, 瀬古玲, 藤川紘樹, 和泉雅之, 梶原康宏, 伊藤幸成, 伊藤幸成

    日本農芸化学会大会講演要旨集(Web)　Vol. 2017　2017

  28. ハイマンノース型糖鎖を有する糖タンパク質プローブを用いた小胞体品質管理機構の解明

    木内達人, 和泉雅之, 岡本亮, 武田陽一, 迫野昌文, 伊藤幸成, 伊藤幸成, 梶原康宏, 梶原康宏

    日本糖質学会年会要旨集　Vol. 35th　2016

  29. 糖タンパク質の品質管理の仕組み : 糖タンパク質の精密化学合成を利用して

    和泉 雅之, 伊藤 幸成, 梶原 康宏

    現代化学　No. 535　p. 48-53　2015/10

    Publisher: 東京化学同人

  30. Functional analysis of endoplasmic reticulum glucosyltransferase (UGGT): Synthetic chemistry's initiative in glycobiology

    Yukishige Ito, Yoichi Takeda, Akira Seko, Masayuki Izumi, Yasuhiro Kajihara

    SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY　Vol. 41　p. 90-98　2015/05　Book review, literature introduction, etc.

  31. Chemical Synthesis of Homogeneous Glycoproteins for the Study of Glycoprotein Quality Control System

    Masayuki Izumi, Simone Dedola, Yukishige Ito, Yasuhiro Kajihara

    ISRAEL JOURNAL OF CHEMISTRY　Vol. 55　No. 3-4　p. 306-314　2015/04　Book review, literature introduction, etc.

  32. 小胞体グルコース転移酵素(UGGT)の非触媒ドメインが糖転移に与える影響

    武田陽一, 瀬古玲, 八須匡和, 和泉雅之, 藤川紘樹, 梶原康宏, 梶原康宏, 伊藤幸成, 伊藤幸成

    日本農芸化学会大会講演要旨集(Web)　Vol. 2015　2015

  33. A synthetic study of a homogeneous hematopoietic glycoprotein bearing three biantennary sialyloligosaccharides

    Masumi Murakami, Ryo Okamoto, Masayuki Izumi, Yasuhiro Kajihara

    GLYCOBIOLOGY　Vol. 24　No. 11　p. 1119-1119　2014/11　Research paper, summary (international conference)

  34. Synthetic Study of Erythropoietin Having High Mannose-type Oligosaccharide by Chemical Methodology

    Tatsuto Kiuchi, Ryo Okamoto, Masayuki Izumi, Akira Seko, Yukishige Ito, Yasuhiro Kajihara

    GLYCOBIOLOGY　Vol. 24　No. 11　p. 1119-1119　2014/11　Research paper, summary (international conference)

  35. Chemical synthesis of misfolded glycoproteins as substrates of folding sensor enzyme UGGT

    Masayuki Izumi, Rie Kuruma, Ryo Okamoto, Akira Seko, Yukishige Ito, Yasuhiro Kajihara

    GLYCOBIOLOGY　Vol. 24　No. 11　p. 1113-1114　2014/11　Research paper, summary (international conference)

  36. Biological activities of the homogeneous glycosylated chemokines CCL1 and Ser-CCL1 prepared by total chemical synthesis

    Ryo Okamoto, Kalyanswer Mandal, Morris Ling, Andrew Luster, Michael Sawaya, Todd Yeates, Yasuhiro Kajihara, Stephen Kent

    GLYCOBIOLOGY　Vol. 24　No. 11　p. 1118-1119　2014/11　Research paper, summary (international conference)

  37. Decoration of proteins with sugar chains: recent advances in glycoprotein synthesis

    Ryo Okamoto, Masayuki Izumi, Yasuhiro Kajihara

    CURRENT OPINION IN CHEMICAL BIOLOGY　Vol. 22　p. 92-99　2014/10　Book review, literature introduction, etc.

  38. 二量体型変性糖タンパク質を用いた糖タンパク質品質管理機構の解明

    小牧慎司, 和泉雅之, 岡本亮, 瀬古玲, 武田陽一, 伊藤幸成, 伊藤幸成, 梶原康宏, 梶原康宏

    日本化学会講演予稿集　Vol. 94th　No. 3　2014

  39. モノグルコシル化ハイマンノース型糖鎖を有する糖タンパク質の立体構造の違いがグルコシダーゼIIの基質認識に与える影響

    岡幸歩, 和泉雅之, 岡本亮, 武田陽一, 瀬古玲, 伊藤幸成, 伊藤幸成, 梶原康宏, 梶原康宏

    日本化学会講演予稿集　Vol. 94th　No. 3　2014

  40. 合成糖鎖を用いた小胞体内グルコース転移酵素(UGGT)のドメイン解析

    武田陽一, 瀬古玲, 八須匡和, 大黒周作, 和泉雅之, 小泉晶彦, 藤川紘樹, 梶原康宏, 梶原康宏, 伊藤幸成, 伊藤幸成

    日本糖質学会年会要旨集　Vol. 33rd　2014

  41. 合成糖鎖を用いたUGGT2の基質特異性解析

    武田陽一, 瀬古玲, 八須匡和, 大黒周作, 和泉雅之, 小泉晶彦, 藤川紘樹, 梶原康宏, 梶原康宏, 伊藤幸成, 伊藤幸成

    日本農芸化学会大会講演要旨集(Web)　Vol. 2014　2014

  42. ハイマンノース型糖鎖を有する糖タンパク質の精密化学合成とそれを利用したフォールディングセンサー酵素UGGTの基質認識機構の解明

    和泉雅之, DEDOLA Simone, DEDOLA Simone, 木内達人, 來間利江, 牧村裕, 牧村裕, 瀬古玲, 金森審子, 迫野昌文, 伊藤幸成, 伊藤幸成, 梶原康宏, 梶原康宏

    天然有機化合物討論会講演要旨集(Web)　Vol. 55th　2013

  43. Misfolded Glycoproteins as Probes for Analysis of Folding Sensor Enzyme UDP-Glucose : Glycoprotein Glucosyltransferase

    Masayuki Izumi, Tatsuto Kiuchi, Yukishige Ito, Yasuhiro Kajihara

    TRENDS IN GLYCOSCIENCE AND GLYCOTECHNOLOGY　Vol. 25　No. 141　p. 1-12　2013/01　Book review, literature introduction, etc.

  44. New Strategy for the Synthesis of Glycoprotein : A Single Expression Method of Two Peptide Segments Encoded as a Tandem Sequence in Plasmid and Its Conversion to Peptide-^αThioester

    KIMURA Motoharu, IZUMI Masayuki, OKAMOTO Ryo, ISHIMIZU Takeshi, KAJIHARA Yasuhiro

    Vol. 2011　p. 15-16　2012/03/01

  45. A Unique Kinetically Controlled Ligation Condition Using N-Acetyl-Guanidine Group for the Chemical Synthesis of a Glycoprotein : Ailim/Icos

    NAKAMACHI Keisuke, OKAMOTO Ryo, KAJIHARA Yasuhiro

    Vol. 2011　p. 17-18　2012/03/01

  46. フォールディングセンサーUGGTの基質認識に重要な変性糖タンパク質の構造

    和泉雅之, DEDOLA Simone, 牧村裕, 瀬古玲, 金森審子, 伊藤幸成, 梶原康宏

    日本化学会講演予稿集　Vol. 92nd　No. 3　2012

  47. Elucidating the Function of Complex-Type Oligosaccharides by Use of Chemical Synthesis of Homogeneous Glycoproteins

    Yasuhiro Kajihara, Masayuki Izumi, Kiriko Hirano, Takefumi Murase, Derek Macmillan, Ryo Okamoto

    ISRAEL JOURNAL OF CHEMISTRY　Vol. 51　No. 8-9　p. 917-929　2011/11　Book review, literature introduction, etc.

  48. Chemical synthesis of glycoproteins having human oligosaccharides

    Vol. 63　No. 4　p. 88-91　2011

    Publisher: 生産技術振興協会

  49. Total Chemical Synthesis of a Glycosyl Chemokine: Ser-CCL1 and Structural Analysis by Quasi-Racemate X-ray Crystallography

    Ryo Okamoto, Kalyaneswar Mandal, Michael Sawaya, Yasuhiro Kajihara, Todd O. Yeates, Stephen B. H. Kent

    BIOPOLYMERS　Vol. 96　No. 4　p. 505-506　2011　Research paper, summary (international conference)

  50. Chemical synthesis of glycoproteins having complex type oligosaccharides

    Vol. 60　No. 1　p. 57-69　2010

    Publisher: 横浜市立大学学術研究会

  51. The study of glycopeptide syntheses: exploring concise O-linked sialylglycopeptide synthesis and glycopeptide coupling reaction

    Ryo Okamoto, Yasuhiro Kajihara

    TRENDS IN GLYCOSCIENCE AND GLYCOTECHNOLOGY　Vol. 20　No. 114　p. 203-217　2008/09　Book review, literature introduction, etc.

  52. Semisynthesis of human complex type oligosaccharide library and chemical synthesis of glycopeptides and glycoprotein

    Ryo Okamoto, Yasuhiro Kajihara

    JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN　Vol. 66　No. 9　p. 893-905　2008/09　Book review, literature introduction, etc.

  53. Stereoselective and efficient total synthesis of optically active tetrodotoxin from D-glucose

    Ken-Ichi Sato, Shoji Akai, Hirotsugu Shoji, Naoki Sugita, Shiho Yoshida, Yoshinao Nagai, Katsuhiko Suzuki, Yutaka Nakamura, Yasuhiro Kajihara, Masuo Funabashi, Juji Yoshimura

    JOURNAL OF ORGANIC CHEMISTRY　Vol. 73　No. 4　p. 1234-1242　2008/02

  54. 糖ペプチドの精密化学合成

    梶原 康宏

    横浜市立大学論叢 自然科学系列　Vol. 57　No. 1　p. 75-85　2007/01

    Publisher: 横浜市立大学学術研究会

  55. 鶏卵を利用した糖鎖の大量合成 (特集2 糖鎖研究をささえる糖鎖合成・精製技術)

    梶原 康宏, 朝井 洋明

    バイオインダストリー　Vol. 22　No. 11　p. 65-69　2005/11

    Publisher: シーエムシー出版

  56. Synthesis of Diverse Asparagine Linked Oligosaccharides

    KAJIHARA Yasuhiro

    Vol. 52　No. 2　p. 177-182　2005/04/20

  57. 酵素化学法を利用した多様な構造の糖鎖合成

    Methods In Enzymology　Vol. 362, 44-64　2003

  58. Solid-phase synthesis of sialylglycopeptides through selective esterification of the sialic acid residues of an Asn-linked complex-type sialyloligosaccharide

    N Yamamoto, Y Ohmori, T Sakakibara, K Sasaki, LR Juneja, Y Kajihara

    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION　Vol. 42　No. 22　p. 2537-2540　2003

  59. Synthesis of new glycopolymers containing beta-D-mannopyranose, and C-2-substituted beta-D-mannopyranose residues as a new class of inhibitor

    S Akai, Y Kajihara, Y Nagashima, M Kamei, J Arai, M Bito, K Sato

    JOURNAL OF CARBOHYDRATE CHEMISTRY　Vol. 20　No. 2　p. 121-143　2001

  60. An approach to the precise chemoenzymatic synthesis of C-13-labeled sialyloligosaccharide on an intact glycoprotein: A novel one-pot [3-C-13]-labeling method for sialic acid analogues by control of the reversible aldolase reaction, enzymatic synthesis of [3-C-13]-NeuAc-alpha-(2 -> 3)-[U-C-13]-Gal-beta-(1 -> 4)-GlcNAc-beta- sequence onto glycoprotein, and its conformational analysis by developed NMR techniques

    T Miyazaki, H Sato, T Sakakibara, Y Kajihara

    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY　Vol. 122　No. 24　p. 5678-5694　2000/06　Book review, literature introduction, etc.

  61. 糖タンパク質上での13C-標識シアリルオリゴ糖の精密合成へのアプローチ

    アメリカ化学会誌　Vol. 122　2000

  62. Crystal structure of (1R,2R,3S,4S,5S,6S,7R,9S)-6-azido-7-cyano-3-C-hydroxy-methyl-3,3 '-di-O-isopropylidene-9-methoxy-2,4,5-tris(O-methoxymethyl)-2,3,4,5-tetrahydroxy-8-oxabicyclo[4.3.0]nonane, toward tetrodotoxin

    S Akai, Y Nakamura, Y Kajihara, J Yoshimura, K Sato

    ANALYTICAL SCIENCES　Vol. 15　No. 5　p. 501-502　1999/05

  63. Chemoenzymatic synthesis of the 9-deoxy-fluoro-[3-C-13]-NeuAc-alpha-(2 -> 6)-[U-C-13]-Gal-beta-sequence on an intact glycoprotein

    T Miyazaki, T Sakakibara, H Sato, Y Kajihara

    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY　Vol. 121　No. 6　p. 1411-1412　1999/02

  64. Selective protecting method for the individual hydroxyl groups of KDN

    S Akai, T Nakagawa, Y Kajihara, K Sato

    JOURNAL OF CARBOHYDRATE CHEMISTRY　Vol. 18　No. 6　p. 639-654　1999

  65. 糖タンパク質上での9-デオキシ-9-フルオロ-[3-13C]-シアリル-α-(2→6)-[U-13C]-ガラクトシル配列の化学酵素法による合成

    アメリカ化学会誌　Vol. 121　No. 6　1999

  66. β-(1→4)-ガラクトース転移酵素の糖受容体の認識の特徴

    炭水化物研究　Vol. 306　p. 361-378　1998

  67. 固定化されたシチジン-5'-リン酸-シアル酸の合成とそのシアル酸転移酵素による転移活性

    応用化学　1998

  68. Novel features of acceptor recognition by beta-(1 -> 4)-galactosyltransferase

    Y Kajihara, H Kodama, T Endo, H Hashimoto

    CARBOHYDRATE RESEARCH　Vol. 306　No. 3　p. 361-378　1998/01

  69. Synthesis of immobilized CMP-sialic acids and their enzymatic transfer with sialyltransferase

    Y Kajihara, T Ebata, H Kodama

    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION　Vol. 37　No. 22　p. 3166-3169　1998

  70. Approach to transition state analogue of glycosyltransferase reaction - Design and synthesis of selective inhibitor of beta-1,4-galactosyltransferase

    H Hashimoto, Y Kajihara

    JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN　Vol. 55　No. 4　p. 325-333　1997/04　Book review, literature introduction, etc.

  71. Synthesis of the first tricomponent bisubstrate analogue that exhibits potent inhibition against GlcNAc:beta-1,4-galactosyltransferase

    H Hashimoto, T Endo, Y Kajihara

    JOURNAL OF ORGANIC CHEMISTRY　Vol. 62　No. 7　p. 1914-1915　1997/04　Rapid communication, short report, research note, etc. (scientific journal)

  72. Useful intermediates, 3-C-dichloromethyl furanose derivatives, for the synthesis of branched-chain functionalized sugars

    K Sato, K Suzuki, M Ueda, Y Kajihara, H Hori

    BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN　Vol. 70　No. 1　p. 225-230　1997/01

  73. New polymeric inhibitor of galactosyl transferase

    K Hatanaka, H Takeshige, KI Kanno, A Maruyama, J Oishi, Y Kajihara, H Hashimoto

    JOURNAL OF CARBOHYDRATE CHEMISTRY　Vol. 16　No. 4-5　p. 667-672　1997

  74. A novel alpha-2,6-sialyltransferase: Transfer of sialic acid to fucosyl and sialyl trisaccharides

    Y Kajihara, T Yamamoto, H Nagae, M Nakashizuka, T Sakakibara, Terada, I

    JOURNAL OF ORGANIC CHEMISTRY　Vol. 61　No. 24　p. 8632-8635　1996/11

  75. EFFICIENT CHEMICAL SYNTHESIS OF CMP-NEU5AC AND CMP-(NEU5AC-ALPHA-2-]-8NEU5AC)

    Y KAJIHARA, T EBATA, K KOSEKI, H KODAMA, H MATSUSHITA, H HASHIMOTO

    JOURNAL OF ORGANIC CHEMISTRY　Vol. 60　No. 17　p. 5732-5735　1995/08　Article, review, commentary, editorial, etc. (scientific journal)

  76. 海洋性細菌JT0160の生産するシアル酸転移酵素の精製 : 酵素

    山本 岳, 中静 素子, 梶原 康宏, 児玉 久, 寺田 一郎

    日本農藝化學會誌　Vol. 69　1995/07/05

    Publisher: 社団法人日本農芸化学会

  77. 海洋性細菌JT0160の生産するシアル酸転移酵素の性質 : 酵素

    山本 岳, 中静 素子, 梶原 康宏, 児玉 久, 寺田 一郎

    日本農藝化學會誌　Vol. 69　1995/07/05

    Publisher: 社団法人日本農芸化学会

  78. SYNTHESIS OF A NOVEL CMP-NEU5AC ANALOG - CMP-[ALPHA-NEU5AC-(2-]8)-NEU5AC]

    Y KAJIHARA, K KOSEKI, T EBATA, H KODAMA, H MATSUSHITA, H HASHIMOTO

    CARBOHYDRATE RESEARCH　Vol. 264　No. 1　p. C1-C5　1994/11　Article, review, commentary, editorial, etc. (scientific journal)

  79. CHARACTERIZATION OF INHIBITORY ACTIVITIES AND BINDING MODE OF SYNTHETIC 6'-MODIFIED METHYL N-ACETYL-BETA-LACTOSAMINIDE TOWARD RAT-LIVER CMP-DEUTERIUM-NEU5ACDEUTERIUM-GALACTOSIDE-(2-]6)-ALPHA-DEUTERIUM-SIALYLTRANSFERASE

    Y KAJIHARA, H KODAMA, T WAKABAYASHI, K SATO, H HASHIMOTO

    CARBOHYDRATE RESEARCH　Vol. 247　p. 179-193　1993/09

  80. SYNTHESIS OF METHYL 6'-DEOXY-LACTOSAMINIDES AND 6'-THIO-LACTOSAMINIDES AND THEIR INHIBITORY ACTIVITY TOWARD CMP-NEUNAC-D-GALACTOSIDE-(2-]6)-ALPHA-D-SIALYLTRANSFERASE

    Y KAJIHARA, H HASHIMOTO, H KODAMA, T WAKABAYASHI, K SATO

    JOURNAL OF CARBOHYDRATE CHEMISTRY　Vol. 12　No. 7　p. 991-995　1993　Article, review, commentary, editorial, etc. (scientific journal)

  81. A NOVEL REAGENT FOR THE SYNTHESIS OF BRANCHED-CHAIN FUNCTIONALIZED SUGARS - DICHLOROMETHYLLITHIUM

    K SATO, K SUZUKI, M UEDA, M KATAYAMA, Y KAJIHARA

    CHEMISTRY LETTERS　No. 8　p. 1469-1472　1991/08

  82. 酵素化学法を利用した多様な構造の糖鎖合成と糖ペプチド合成への応用

    Chemistry A European Jouranl　Vol. 印刷中

Publications 2

  1. Glycobiophysics

    KAJIHARA Yasuhiro

    Springer　2018

  2. Glycochemical synthesis

    KAJIHARA Yasuhiro

    Wiley　2016

Presentations 8

  1. N-Glycans on Proteins

    KAJIHARA Yasuhiro

    E. Fischer memorial symposium "What would E Fischer do todays?", Berlin　2019/12/09

  2. Chemical Synthesis of homogeneous glycoprotein having triantennary glycan

    KAJIHARA Yasuhiro

    Solid phase peptide synthesis, Australia　2019/09

  3. Semi-Synthesis of homogeneous glycoproteins

    KAJIHARA Yasuhiro

    Australian peptide symposium　2019/09

  4. Function of N-glycan on protein

    KAJIHARA Yasuhiro

    American Chemical Society national meeting　2019/08

  5. Function of N-glycan on protein

    KAJIHARA Yasuhiro

    Chemical Protein synthesis, Berlin　2019/06

  6. N Acetyl neuraminic acid

    KAJIHARA Yasuhiro

    Sialobiology, Banff　2019/05

  7. N-Glycan on Protein

    KAJIHARA Yasuhiro

    International Carbohydrate Symposium, Lisbon　2018/07

  8. Synthesis of glycoconjugate for elucidation of oligosaccharide functions

    KAJIHARA Yasuhiro

    Gordon Research Conference,　2017/06

Industrial Property Rights 2

  1. 糖鎖アスパラギンを有する糖ペプチドの製造方法および該糖ペプチド

  2. 糖鎖アスパラギン誘導体の製造方法

Institutional Repository 2

Content Published in the University of Osaka Institutional Repository (OUKA)

  1. Harnessing Free Sulfate Groups in Glycosylation Reactions

    Maki Yuta, Manbo Akihiro, Abe Junpei, Nobutou Hiroki, Hirao Kohtaro, Okamoto Ryo, Izumi Masayuki, Yamanaka Shusuke, Okumura Mitsutaka, Kajihara Yasuhiro

    Angewandte Chemie - International Edition　Vol. 64　No. 4　2025/01/21

  2. Uncovering a Latent Bioactive Interleukin-6 Glycoform

    Liu Yanbo, Maki Yuta, Okamoto Ryo, Satoh Ayano, Todokoro Yasuto, Kanemitsu Yurie, Otani Keito, Kajihara Yasuhiro

    Angewandte Chemie - International Edition　Vol. 63　No. 50　2024/12/09