HT-SELEX-based identification of binding pre-miRNA hairpin-motif for small molecules.

Sanjukta Mukherjee, Asako Murata, Ryoga Ishida, Ayako Sugai, Chikara Dohno, Michiaki Hamada, Sudhir Krishna, Kazuhiko Nakatani

Molecular therapy. Nucleic acids　Vol. 27　p. 165-174　2022/03/08　Research paper (scientific journal)

Short Tandem Repeat Contractions during in Vitro DNA Synthesis by Repeat-binding Molecules

Masaki Hagihara, Chikara Dohno, Kaoru Saito, Kazuhiro Sugimoto, Yuta Hishinuma, Yuri Sohma, Tomonori Shibata, Kazuhiko Nakatani

Chemistry Letters　Vol. 50　No. 11　p. 1851-1848　2021/11　Research paper (scientific journal)

Cyclic mismatch binding ligands interact with disease-associated CGG trinucleotide repeats in RNA and suppress their translation.

Patryk Konieczny, Sanjukta Mukherjee, Ewa Stepniak-Konieczna, Katarzyna Taylor, Daria Niewiadomska, Agnieszka Piasecka, Agnieszka Walczak, Anna Baud, Chikara Dohno, Kazuhiko Nakatani, Krzysztof Sobczak

Nucleic acids research　Vol. 49　No. 16　p. 9479-9495　2021/09/20　Research paper (scientific journal)

Rational design of a photoswitchable DNA glue enabling high regulatory function and supramolecular chirality transfer

Nadja A. Simeth, Shotaro Kobayashi, Piermichele Kobauri, Stefano Crespi, Wiktor Szymanski, Kazuhiko Nakatani, Chikara Dohno, Ben L. Feringa

Chemical Science　Vol. 12　No. 26　p. 9207-9220　2021/05　Research paper (scientific journal)

Small molecule-induced trinucleotide repeat contractions during in vitro DNA synthesis

Chikara Dohno, Masaki Hagihara, Nursakinah Binti Mohd Zaifuddin, Mizuki Nihei, Kaoru Saito, Kazuhiko Nakatani

Chemical Communications　Vol. 57　No. 26　p. 3235-3238　2021/03　Research paper (scientific journal)

The Dimeric Form of 1,3‐Diaminoisoquinoline Derivative Rescued the Mis‐splicing of Atp2a1 and Clcn1 Genes in Myotonic Dystrophy Type 1 Mouse Model

Jun Matsumoto, Masayuki Nakamori, Tatsumasa Okamoto, Asako Murata, Chikara Dohno, Kazuhiko Nakatani

Chemistry – A European Journal　Vol. 26　No. 63　p. 14305-14309　2020/11/11　Research paper (scientific journal)

Recognition of expanded GGGGCC hexanucleotide repeat by synthetic ligand through interhelical binding

Yihuan Lu, Chikara Dohno, Kazuhiko Nakatani

Biochemical and Biophysical Research Communications　Vol. 531　No. 1　p. 56-61　2020/10　Research paper (scientific journal)

A novel naphthyridine tetramer that recognizes tandem G-G mismatches by the formation of an interhelical complex

Yihuan Lu, Chikara Dohno, Kazuhiko Nakatani

Chemical Communications　Vol. 56　No. 5　p. 754-757　2020　Research paper (scientific journal)

Molecular Glue for RNA: Regulating RNA Structure and Function through Synthetic RNA Binding Molecules

Chikara Dohno, Kazuhiko Nakatani

ChemBioChem　Vol. 20　No. 23　p. 2903-2910　2019/12/02　Research paper (scientific journal)

Structural insights into synthetic ligands targeting A–A pairs in disease-related CAG RNA repeats

Mukherjee, S, Błaszczyk, L, Rypniewski, W, Falschlunger, C, Micura, R, Murata, A, Dohno, C, Nakatani, K, Kiliszek, A

Nucl. Acids Res.　Vol. 47　No. 20　p. 10906-10913　2019/11　Research paper (scientific journal)

A Dimeric 2,9-Diamino-1,10-phenanthroline Derivative Improves Alternative Splicing in Myotonic Dystrophy Type 1 Cell and Mouse Models

Li Jinxing, Nakamori Masayuki, Matsumoto Jun, Murata Asako, Dohno Chikara, Kiliszek Agnieszka, Taylor Katarzyna, Sobczak Krzysztof, Nakatani Kazuhiko

CHEMISTRY-A EUROPEAN JOURNAL　Vol. 24　No. 68　p. 18115-18122　2018/12/05

Restoration of Ribozyme Tertiary Contact and Function by Using a Molecular Glue for RNA

Chikara Dohno, Maki Kimura, Kazuhiko Nakatani

Angewandte Chemie International Edition　Vol. 57　No. 2　p. 506-510　2018/01/08　Research paper (scientific journal)

Design and Synthesis of Cyclic Mismatch-Binding Ligands (CMBLs) with Variable Linkers by Ring-Closing Metathesis and their Photophysical and DNA Repeat Binding Properties

Sanjukta Mukherjee, Chikara Dohno, Kazuhiko Nakatani

CHEMISTRY-A EUROPEAN JOURNAL　Vol. 23　No. 47　p. 11385-11396　2017/08　Research paper (scientific journal)

Amphiphilic DNA tiles for controlled insertion and 2D assembly on fluid lipid membranes: the effect on mechanical properties

Chikara Dohno, Shingo Makishi, Kazuhiko Nakatani, Sonia Contera

NANOSCALE　Vol. 9　No. 9　p. 3051-3058　2017/03　Research paper (scientific journal)

A Ligand That Targets CUG Trinucleotide Repeats

Jinxing Li, Jun Matsumoto, Li-Ping Bai, Asako Murata, Chikara Dohno, Kazuhiko Nakatani

CHEMISTRY-A EUROPEAN JOURNAL　Vol. 22　No. 42　p. 14881-14889　2016/10　Research paper (scientific journal)

Cyclic mismatch binding ligand CMBL4 binds to the 5 '-T-3 '/5 '-GG-3 ' site by inducing the flipping out of thymine base

Sanjukta Mukherjee, Chikara Dohno, Kaori Asano, Kazuhiko Nakatani

NUCLEIC ACIDS RESEARCH　Vol. 44　No. 15　p. 7090-7099　2016/09　Research paper (scientific journal)

Synthesis of 1H-pyrrolo[3,2-h]quinoline-8-amine derivatives that target CTG trinucleotide repeats

Jun Matsumoto, Jinxing Li, Chikara Dohno, Kazuhiko Nakatani

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS　Vol. 26　No. 15　p. 3761-3764　2016/08　Research paper (scientific journal)

Naphthyridine-Benzoazaquinolone: Evaluation of a Tricyclic System for the Binding to (CAG)(n) Repeat DNA and RNA

Jinxing Li, Akihiro Sakata, Hanping He, Li-Ping Bai, Asako Murata, Chikara Dohno, Kazuhiko Nakatani

CHEMISTRY-AN ASIAN JOURNAL　Vol. 11　No. 13　p. 1971-1981　2016/07　Research paper (scientific journal)

Non-covalent Modification of Double-Stranded DNA at the Mismatch and Bulged Site

Chikara Dohno, Kazuhiko Nakatani

Nucleic Acids and Molecular Biology　p. 189-207　2016/04/05　Part of collection (book)

A hybridisation-dependent membrane-insertable amphiphilic DNA

C. Dohno, K. Matsuzaki, H. Yamaguchi, T. Shibata, K. Nakatani

Organic and Biomolecular Chemistry　Vol. 13　No. 40　p. 10117-10121　2015/09/15　Research paper (scientific journal)

2-Aminophenanthroline dimer stabilized the C-C mismatched duplex DNA

Jinxing Li, Jun Matsumoto, Takahiro Otabe, Chikara Dohno, Kazuhiko Nakatani

BIOORGANIC & MEDICINAL CHEMISTRY　Vol. 23　No. 4　p. 753-758　2015/02　Research paper (scientific journal)

Modulation of binding properties of amphiphilic DNA containing multiple dodecyl phosphotriester linkages to lipid bilayer membrane

Shingo Makishi, Tomonori Shibata, Masatsugu Okazaki, Chikara Dohno, Kazuhiko Nakatani

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS　Vol. 24　No. 15　p. 3578-3581　2014/08　Research paper (scientific journal)

Formation of a Ligand- Assisted Complex of Two RNA Hairpin Loops

Changfeng Hong, Takahiro Otabe, Saki Matsumoto, Chikara Dohno, Asako Murata, Masaki Hagihara, Kazuhiko Nakatani

CHEMISTRY-A EUROPEAN JOURNAL　Vol. 20　No. 18　p. 5282-5287　2014/04　Research paper (scientific journal)

Cytosine-bulge-dependent fluorescence quenching for the real-time hairpin primer PCR

F. Takei, X. Chen, G. Yu, T. Shibata, C. Dohno, K. Nakatani

CHEMICAL COMMUNICATIONS　Vol. 50　No. 96　p. 15195-15198　2014　Research paper (scientific journal)

A Synthetic Riboswitch that Operates using a Rationally Designed Ligand-RNA Pair

Chikara Dohno, Izumi Kohyama, Maki Kimura, Masaki Hagihara, Kazuhiko Nakatani

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION　Vol. 52　No. 38　p. 9976-9979　2013/09　Research paper (scientific journal)

Triethynylmethane: a molecular unit inducing excimer-like emission in aggregated states of hydrocarbon fluorophores

Takahiro Otabe, Saki Matsumoto, Hiroki Nakagawa, Changfeng Hong, Chikara Dohno, Kazuhiko Nakatani

TETRAHEDRON LETTERS　Vol. 54　No. 2　p. 143-146　2013/01　Research paper (scientific journal)

G-quadruplex formation of entirely hydrophobic DNA in organic solvents

Tomonori Shibata, Chikara Dohno, Kazuhiko Nakatani

CHEMICAL COMMUNICATIONS　Vol. 49　No. 48　p. 5501-5503　2013　Research paper (scientific journal)

Ligand-induced electron spin-assembly on a DNA tile

Hiroshi Atsumi, Shigeaki Nakazawa, Chikara Dohno, Kazunobu Sato, Takeji Takui, Kazuhiko Nakatani

CHEMICAL COMMUNICATIONS　Vol. 49　No. 57　p. 6370-6372　2013　Research paper (scientific journal)

Assembly of a Small DNA Rectangular Parallelepiped Block into Higher Order Nanostructures

Hiroyuki Nakagawa, Mariko Toda, Hiroshi Atsumi, Masaki Hagihara, Mitsuko Hayashi-Nishino, Chikara Dohno, Kazuhiko Nakatani

CHEMISTRY LETTERS　Vol. 41　No. 11　p. 1550-1552　2012/11　Research paper (scientific journal)

Amphiphilic DNA Duplex Stabilized by a Hydrophobic Zipper

Chikara Dohno, Tomonori Shibata, Masatsugu Okazaki, Shingo Makishi, Kazuhiko Nakatani

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY　No. 27　p. 5317-5323　2012/09　Research paper (scientific journal)

Naphthyridine tetramer with a pre-organized structure for 1:1 binding to a CGG/CGG sequence

Chikara Dohno, Izumi Kohyama, Changfeng Hong, Kazuhiko Nakatani

NUCLEIC ACIDS RESEARCH　Vol. 40　No. 6　p. 2771-2781　2012/03　Research paper (scientific journal)

Fluorescence-based binding assay of hydrophobic DNA to the lipid bilayer membrane

Shibata Tomonori, Makishi Shingo, Dohno Chikara, Nakatani Kazuhiko

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY　Vol. 243　2012/03

Interstrand Crosslink for Discrimination of Methylated Cytosines

Chikara Dohno, Tomonori Shibata, Kazuhiko Nakatani

CHEMISTRY LETTERS　Vol. 40　No. 8　p. 852-854　2011/08　Research paper (scientific journal)

Molecular-Glue-Triggered DNA Assembly To Form a Robust and Photoresponsive Nano-Network

Chunyan Wang, Fang Pu, Youhui Lin, Jinsong Ren, Chikara Dohn, Kazuhiko Nakatani, Xiaogang Qu

CHEMISTRY-A EUROPEAN JOURNAL　Vol. 17　No. 29　p. 8189-8194　2011/07　Research paper (scientific journal)

Ligand inducible assembly of a DNA tetrahedron

Chikara Dohno, Hiroshi Atsumi, Kazuhiko Nakatani

CHEMICAL COMMUNICATIONS　Vol. 47　No. 12　p. 3499-3501　2011　Research paper (scientific journal)

Control of DNA hybridization by photoswitchable molecular glue

Chikara Dohno, Kazuhiko Nakatani

CHEMICAL SOCIETY REVIEWS　Vol. 40　No. 12　p. 5718-5729　2011

Discrimination of N6-methyl adenine in a specific DNA sequence

Chikara Dohno, Tomonori Shibata, Kazuhiko Nakatani

CHEMICAL COMMUNICATIONS　Vol. 46　No. 30　p. 5530-5532　2010　Research paper (scientific journal)

Photoswitchable Unsymmetrical Ligand for DNA Hetero-Mismatches

Chikara Dohno, Tsuyoshi Yamamoto, Kazuhiko Nakatani

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY　No. 24　p. 4051-4058　2009/08　Research paper (scientific journal)

The effect of linker length on binding affinity of a photoswitchable molecular glue for DNA

Chikara Dohno, Shin-Nosuke Uno, Shun Sakai, Mika Oku, Kazuhiko Nakatani

BIOORGANIC & MEDICINAL CHEMISTRY　Vol. 17　No. 6　p. 2536-2543　2009/03　Research paper (scientific journal)

DNA cross-link generated by a novel modified DNA containing a formyl group.

Shibata T, Dohno C, Nakatani K

Nucleic acids symposium series (2004)　No. 53　p. 171-172　2009

A Light-Driven Supramolecular Optical Switch

Shin-nosuke Uno, Chikara Dohno, Holger Bittermann, Vladimir L. Malinovskii, Robert Haener, Kazuhiko Nakatani

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION　Vol. 48　No. 40　p. 7362-7365　2009　Research paper (scientific journal)

Synthesis of dimeric 2-amino-1,8-naphthyridine and related DNA-binding molecules

Kazuhiko Nakatani, Hanping He, Shin-Nosuke Uno, Tsuyoshi Yamamoto, Chikara Dohno

Current Protocols in Nucleic Acid Chemistry　No. 32　2008

Photoswitchable molecular glue for DNA

Chikara Dohno, Shin-Nosuke Uno, Kazuhiko Nakatani

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY　Vol. 129　No. 39　p. 11898-+　2007/10　Research paper (scientific journal)

Photoregulation of a peptide-RNA interaction on a gold surface

Gosuke Hayashi, Masaki Hagihara, Chikara Dohno, Kazuhiko Nakatani

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY　Vol. 129　No. 28　p. 8678-+　2007/07　Research paper (scientific journal)

Bidirectional control of gold nanoparticle assembly by turning on and off DNA hybridization with thermally degradable molecular glue

Tao Peng, Chikara Dohno, Kazuhiko Nakatani

CHEMBIOCHEM　Vol. 8　No. 5　p. 483-485　2007/03　Research paper (scientific journal)

Reversible control of DNA hybridization by photoresponsive ligands.

Shin-Nosuke Uno, Chikara Dohno, Mika Oku, Kazuhiko Nakatani

Nucleic acids symposium series (2004)　No. 51　p. 173-174　2007　Research paper (scientific journal)

Reversible regulation of binding between a photoresponsive peptide and its RNA aptamer.

Gosuke Hayashi, Masaki Hagihara, Chikara Dohno, Kazuhiko Nakatani

Nucleic acids symposium series (2004)　No. 51　p. 93-94　2007　Research paper (scientific journal)

Highly selective fluorescent nucleobases for designing base-discriminating fluorescent probes

Isao Saito, Yoshio Saito, Kazuo Hanawa, Keigo Hayashi, Kaori Motegi, Subhendu Sekhar Bag, Chikara Dohno, Tomohisa Ichiba, Kazuki Tainaka, Akirnitsu Okamoto

PURE AND APPLIED CHEMISTRY　Vol. 78　No. 12　p. 2305-2312　2006/12　Research paper (scientific journal)

Efficient DNA alkylation by a pyrrole-imidazole CBI conjugate with an indole linker: Sequence-specific alkylation with nine-base-pair recognition

T Bando, S Sasaki, M Minoshima, C Dohno, K Shinohara, A Narita, H Sugiyama

BIOCONJUGATE CHEMISTRY　Vol. 17　No. 3　p. 715-720　2006/05　Research paper (scientific journal)

Chemical Approach to Modulating Hole Transport Through DNA

Chikara Dohno, Isao Saito

Charge Transfer in DNA: From Mechanism to Application　p. 153-174　2006/02/09　Part of collection (book)

Control of DNA hybridization by photoswitchable mismatch binding ligands.

Dohno C, Uno SN, Nakatani K

Nucleic acids symposium series (2004)　No. 50　p. 87-88　2006

Mismatch-binding ligands function as a molecular glue for DNA

Tao Peng, Chikara Dohno, Kazuhiko Nakatani

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION　Vol. 45　No. 34　p. 5623-5626　2006　Research paper (scientific journal)

Stable, specific, and reversible base pairing via Schiff base

C Dohno, A Okamoto, Saito, I

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY　Vol. 127　No. 47　p. 16681-16684　2005/11　Research paper (scientific journal)

Discrimination of single-nucleotide alterations by G-specific fluorescence quenching

C Dohno, Saito, I

CHEMBIOCHEM　Vol. 6　No. 6　p. 1075-1081　2005/06　Research paper (scientific journal)

Schiff base-mediated base pairing.

Dohno C, Okamoto A, Saito I

Nucleic acids symposium series (2004)　No. 49　p. 185-186　2005

Effects of the photooxidant on DNA-mediated charge transport

TT Williams, C Dohno, EDA Stemp, JK Barton

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY　Vol. 126　No. 26　p. 8148-8158　2004/07　Research paper (scientific journal)

Direct chemical evidence for charge transfer between photoexcited 2-aminopurine and guanine in duplex DNA

MA O'Neill, C Dohno, JK Barton

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY　Vol. 126　No. 5　p. 1316-1317　2004/02　Research paper (scientific journal)

Base-discriminating fluorescent DNA probe based on the guanine-specific fluorescence quenching.

Chikara Dohno, Isao Saito

Nucleic acids symposium series (2004)　No. 48　p. 93-94　2004　Research paper (scientific journal)

Hole trapping at N-6-cyclopropyideoxyadenosine suggests a direct contribution of adenine bases to hole transport through DNA

C Dohno, A Ogawa, K Nakatani, Saito, I

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY　Vol. 125　No. 34　p. 10154-10155　2003/08　Research paper (scientific journal)

Fast back electron transfer prevents guanine damage by photoexcited thionine bound to DNA

C Dohno, EDA Stemp, JK Barton

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY　Vol. 125　No. 32　p. 9586-9587　2003/08　Research paper (scientific journal)

Guanine of the third strand of C center dot G*G triplex serves as an effective hole trap

C Dohno, K Nakatani, Saito, I

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY　Vol. 124　No. 49　p. 14580-14585　2002/12　Research paper (scientific journal)

N-2-Phenyldeoxyguanosine: Modulation of the chemical properties of deoxyguanosine toward one-electron oxidation in DNA

K Nakatani, C Dohno, Saito, I

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY　Vol. 124　No. 24　p. 6802-6803　2002/06　Research paper (scientific journal)

Suppression of DNA-mediated charge transport by BamHI binding

K Nakatani, C Dohno, A Ogawa, Saito, I

CHEMISTRY & BIOLOGY　Vol. 9　No. 3　p. 361-366　2002/03　Research paper (scientific journal)

Modulation of remote DNA oxidation by hybridization with peptide nucleic acids (PNA)

A Okamoto, K Tanabe, C Dohno, Saito, I

BIOORGANIC & MEDICINAL CHEMISTRY　Vol. 10　No. 3　p. 713-718　2002/03　Research paper (scientific journal)

Design of a hole-trapping nucleobase: Termination of DNA-mediated hole transport at N-2-cyclopropyldeoxyguanosine

K Nakatani, C Dohno, Saito, I

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY　Vol. 123　No. 39　p. 9681-9682　2001/10　Research paper (scientific journal)

Modulation of DNA-mediated hole transport efficiency by DNA-protein complex formation.

C. Dohno, K. Nakatani, I. Saito

Nucleic acids research. Supplement (2001)　No. 1　p. 15-16　2001　Research paper (scientific journal)

Site selective generation of guanine radical cation in duplex DNA: modulation of the direction of hole transport

K Nakatani, C Dohno, Saito, I

TETRAHEDRON LETTERS　Vol. 41　No. 51　p. 10041-10045　2000/12　Research paper (scientific journal)

Modulation of DNA-mediated hole-transport efficiency by changing superexchange electronic interaction

K Nakatani, C Dohno, Saito, I

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY　Vol. 122　No. 24　p. 5893-5894　2000/06　Research paper (scientific journal)

Chemistry of sequence-dependent remote guanine oxidation: Photoreaction of duplex DNA containing cyanobenzophenone-substituted uridine

K Nakatani, C Dohno, Saito, I

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY　Vol. 121　No. 46　p. 10854-10855　1999/11　Research paper (scientific journal)

Synthesis of DNA oligomers containing modified uracil possessing electron-accepting benzophenone chromophore

K Nakatani, C Dohno, Saito, I

JOURNAL OF ORGANIC CHEMISTRY　Vol. 64　No. 18　p. 6901-6904　1999/09　Research paper (scientific journal)

p-Cyano substituted 5-benzoyldeoxyuridine as a novel electron-accepting nucleobase for one-electron oxidation of DNA

K Nakatani, K Fujisawa, C Dohno, T Nakamura, Saito, I

TETRAHEDRON LETTERS　Vol. 39　No. 33　p. 5995-5998　1998/08　Research paper (scientific journal)

p-cyano substituted benzophenone as an excellent photophore for one-electron oxidation of DNA

K Nakatani, C Dohno, T Nakamura, Saito, I

TETRAHEDRON LETTERS　Vol. 39　No. 18　p. 2779-2782　1998/04　Research paper (scientific journal)

-GG- specific cleavage via hole hopping through double-stranded DNA.

T. Nakamura, C. Dohno, K. Nakatani, I. Saito

Nucleic acids symposium series　No. 37　p. 87-88　1997　Research paper (scientific journal)