Vertebrate centromeres in mitosis are functionally bipartite structures stabilized by cohesin.

Carlos Sacristan, Kumiko Samejima, Lorena Andrade Ruiz, Moonmoon Deb, Maaike L A Lambers, Adam Buckle, Chris A Brackley, Daniel Robertson, Tetsuya Hori, Shaun Webb, Robert Kiewisz, Tristan Bepler, Eloïse van Kwawegen, Patrik Risteski, Kruno Vukušić, Iva M Tolić, Thomas Müller-Reichert, Tatsuo Fukagawa, Nick Gilbert, Davide Marenduzzo, William C Earnshaw, Geert J P L Kops

Cell　Vol. 187　No. 12　p. 3006-3023　2024/06/06　Research paper (scientific journal)

Disordered region of nuclear membrane protein Bqt4 recruits phosphatidic acid to the nuclear envelope to maintain its structural integrity.

Yasuhiro Hirano, Tsukino Sato, Ayane Miura, Yoshino Kubota, Tomoko Shindo, Koichi Fukase, Tatsuo Fukagawa, Kazuya Kabayama, Tokuko Haraguchi, Yasushi Hiraoka

The Journal of biological chemistry　Vol. 300　No. 7　p. 107430-107430　2024/05/31　Research paper (scientific journal)

Correction: A ubiquitin-proteasome pathway degrades the inner nuclear membrane protein Bqt4 to maintain nuclear membrane homeostasis.

Toan Khanh Le, Yasuhiro Hirano, Haruhiko Asakawa, Koji Okamoto, Tatsuo Fukagawa, Tokuko Haraguchi, Yasushi Hiraoka

Journal of cell science　Vol. 137　No. 2　2024/01/15

Artificial tethering of constitutive centromere-associated network proteins induces CENP-A deposition without Knl2 in DT40 cells

Jing Hui Cao, Tetsuya Hori, Mariko Ariyoshi, Tatsuo Fukagawa

Journal of Cell Science　Vol. 137　No. 3　2024　Research paper (scientific journal)

CENP-A and CENP-B collaborate to create an open centromeric chromatin state.

Harsh Nagpal, Ahmad Ali-Ahmad, Yasuhiro Hirano, Wei Cai, Mario Halic, Tatsuo Fukagawa, Nikolina Sekulić, Beat Fierz

Nature communications　Vol. 14　No. 1　p. 8227-8227　2023/12/12　Research paper (scientific journal)

An updated view of the kinetochore architecture.

Mariko Ariyoshi, Tatsuo Fukagawa

Trends in genetics : TIG　2023/09/27　Research paper (scientific journal)

Mitotic perturbation is a key mechanism of action of decitabine in myeloid tumor treatment.

Tomohiro Yabushita, Takumi Chinen, Atsuya Nishiyama, Shuhei Asada, Ruka Shimura, Tomoya Isobe, Keita Yamamoto, Naru Sato, Yutaka Enomoto, Yosuke Tanaka, Tomofusa Fukuyama, Hitoshi Satoh, Keiko Kato, Kaori Saitoh, Takamasa Ishikawa, Tomoyoshi Soga, Yasuhito Nannya, Tatsuo Fukagawa, Makoto Nakanishi, Daiju Kitagawa, Toshio Kitamura, Susumu Goyama

Cell reports　Vol. 42　No. 9　p. 113098-113098　2023/09/26　Research paper (scientific journal)

A ubiquitin-proteasome pathway degrades the inner nuclear membrane protein Bqt4 to maintain nuclear membrane homeostasis.

Toan Khanh Le, Yasuhiro Hirano, Haruhiko Asakawa, Koji Okamoto, Tatsuo Fukagawa, Tokuko Haraguchi, Yasushi Hiraoka

Journal of cell science　2023/09/11　Research paper (scientific journal)

Centromere/kinetochore is assembled through CENP-C oligomerization

Masatoshi Hara, Mariko Ariyoshi, Tomoki Sano, Ryu-Suke Nozawa, Soya Shinkai, Shuichi Onami, Isabelle Jansen, Toru Hirota, Tatsuo Fukagawa

Molecular Cell　Vol. 83　No. 13　p. 2188-2205.e13　2023/07　Research paper (scientific journal)

Ceramide synthase homolog Tlc4 maintains nuclear envelope integrity via its Golgi translocation

Yasuhiro Hirano, Yusuke Ohno, Yoshino Kubota, Tatsuo Fukagawa, Akio Kihara, Tokuko Haraguchi, Yasushi Hiraoka

Journal of Cell Science　2023/05/15　Research paper (scientific journal)

Let's enjoy the heated "Debate Forum" (Gekiron Colosseo) at Makuhari Messe: A report of the 45th Annual Meeting of the Molecular Biology Society of Japan (MBSJ2022).

Tatsuo Fukagawa

Genes to cells : devoted to molecular & cellular mechanisms　2023/03/16　Research paper (scientific journal)

Evolutionary analysis of a complete chicken genome.

Zhen Huang, Zaoxu Xu, Hao Bai, Yongji Huang, Na Kang, Xiaoting Ding, Jing Liu, Haoran Luo, Chentao Yang, Wanjun Chen, Qixin Guo, Lingzhan Xue, Xueping Zhang, Li Xu, Meiling Chen, Honggao Fu, Youling Chen, Zhicao Yue, Tatsuo Fukagawa, Shanlin Liu, Guobin Chang, Luohao Xu

Proceedings of the National Academy of Sciences of the United States of America　Vol. 120　No. 8　2023/02/21　Research paper (scientific journal)

The cryo-EM structure of the CENP-A nucleosome in complex with ggKNL2

Honghui Jiang, Mariko Ariyoshi, Reito Watanabe, Fumiaki Makino, Keiichi Namba, Tatsuo Fukagawa

The EMBO journal　Vol. 42　No. 6　2023/02/06　Research paper (scientific journal)

Transgenerational epigenetic control of constitutive heterochromatin, transposons, and centromeres.

Tatsuo Fukagawa, Tetsuji Kakutani

Current opinion in genetics & development　Vol. 78　p. 102021-102021　2023/02　Research paper (scientific journal)

Kinetochore Architecture Employs Diverse Linker Strategies Across Evolution.

Shreyas Sridhar, Tatsuo Fukagawa

Frontiers in cell and developmental biology　Vol. 10　p. 862637-862637　2022/06　Research paper (scientific journal)

Recruitment of two Ndc80 complexes via the CENP-T pathway is sufficient for kinetochore functions.

Yusuke Takenoshita, Masatoshi Hara, Tatsuo Fukagawa

Nature communications　Vol. 13　No. 1　p. 851-851　2022/02/14　Research paper (scientific journal)

Transfected plasmid DNA is incorporated into the nucleus via nuclear envelope reformation at telophase.

Tokuko Haraguchi, Takako Koujin, Tomoko Shindo, Şükriye Bilir, Hiroko Osakada, Kohei Nishimura, Yasuhiro Hirano, Haruhiko Asakawa, Chie Mori, Shouhei Kobayashi, Yasushi Okada, Yuji Chikashige, Tatsuo Fukagawa, Shinsuke Shibata, Yasushi Hiraoka

Communications biology　Vol. 5　No. 1　p. 78-78　2022/01/20　Research paper (scientific journal)

Mobility of kinetochore proteins measured by FRAP analysis in living cells.

Reito Watanabe, Yasuhiro Hirano, Masatoshi Hara, Yasushi Hiraoka, Tatsuo Fukagawa

Chromosome Research　2022/01/08　Research paper (scientific journal)

A Simple Method that Combines CRISPR and AID to Quickly Generate Conditional Knockouts for Essential Genes in Various Vertebrate Cell Lines.

Kohei Nishimura, Tatsuo Fukagawa

Methods in molecular biology (Clifton, N.J.)　Vol. 2377　p. 109-122　2022　Research paper (scientific journal)

Bub1 and CENP-U redundantly recruit Plk1 to stabilize kinetochore-microtubule attachments and ensure accurate chromosome segregation.

Qinfu Chen, Miao Zhang, Xuan Pan, Xueying Yuan, Linli Zhou, Lu Yan, Ling-Hui Zeng, Junfen Xu, Bing Yang, Long Zhang, Jun Huang, Weiguo Lu, Tatsuo Fukagawa, Fangwei Wang, Haiyan Yan

Cell reports　Vol. 36　No. 12　p. 109740-109740　2021/09/21　Research paper (scientific journal)

A Simple Method to Generate Super-sensitive AID (ssAID)-based Conditional Knockouts using CRISPR-based Gene Knockout in Various Vertebrate Cell Lines.

Kohei Nishimura, Tatsuo Fukagawa

Bio-protocol　Vol. 11　No. 14　2021/07/20　Research paper (scientific journal)

Kinetochore stretching-mediated rapid silencing of the spindle-assembly checkpoint required for failsafe chromosome segregation.

Kazuhiko S K Uchida, Minji Jo, Kota Nagasaka, Motoko Takahashi, Norihisa Shindo, Katsushi Shibata, Kozo Tanaka, Hiroshi Masumoto, Tatsuo Fukagawa, Toru Hirota

Current biology : CB　Vol. 31　No. 8　p. 1581-1591　2021/04/26　Research paper (scientific journal)

Cryo-EM structure of the CENP-A nucleosome in complex with phosphorylated CENP-C.

Mariko Ariyoshi, Fumiaki Makino, Reito Watanabe, Reiko Nakagawa, Takayuki Kato, Keiichi Namba, Yasuhiro Arimura, Risa Fujita, Hitoshi Kurumizaka, Ei-Ichi Okumura, Masatoshi Hara, Tatsuo Fukagawa

The EMBO journal　Vol. 40　No. 5　2021/01/19　Research paper (scientific journal)

Bridgin connects the outer kinetochore to centromeric chromatin.

Shreyas Sridhar, Tetsuya Hori, Reiko Nakagawa, Tatsuo Fukagawa, Kaustuv Sanyal

Nature communications　Vol. 12　No. 1　p. 146-146　2021/01/08　Research paper (scientific journal)

CENP-C Phosphorylation by CDK1 in vitro.

Reito Watanabe, Masatoshi Hara, Mariko Ariyoshi, Tatsuo Fukagawa

Bio-protocol　Vol. 11　No. 1　2021/01/05　Research paper (scientific journal)

Essentiality of CENP-A Depends on Its Binding Mode to HJURP.

Tetsuya Hori, JingHui Cao, Kohei Nishimura, Mariko Ariyoshi, Yasuhiro Arimura, Hitoshi Kurumizaka, Tatsuo Fukagawa

Cell reports　Vol. 33　No. 7　p. 108388-108388　2020/11/17　Research paper (scientific journal)

A super-sensitive auxin-inducible degron system with an engineered auxin-TIR1 pair.

Kohei Nishimura, Ryotaro Yamada, Shinya Hagihara, Rie Iwasaki, Naoyuki Uchida, Takumi Kamura, Koji Takahashi, Keiko U Torii, Tatsuo Fukagawa

Nucleic acids research　Vol. 48　No. 18　2020/09/17　Research paper (scientific journal)

H3K9me3 maintenance on a Human Artificial Chromosome is required for segregation but not centromere epigenetic memory.

Nuno M C Martins, Fernanda Cisneros-Soberanis, Elisa Pesenti, Natalia Y Kochanova, Wei-Hao Shang, Tetsuya Hori, Takahiro Nagase, Hiroshi Kimura, Vladimir Larionov, Hiroshi Masumoto, Tatsuo Fukagawa, William C Earnshaw

Journal of cell science　Vol. 133　No. 14　2020/06/23　Research paper (scientific journal)

CENP-50 is required for papilloma development in the two-stage skin carcinogenesis model.

Megumi Saito, Naoko Kagawa, Kazuhiro Okumura, Haruka Munakata, Eriko Isogai, Tatsuo Fukagawa, Yuichi Wakabayashi

Cancer science　Vol. 111　No. 8　p. 2850-2860　2020/06/14　Research paper (scientific journal)

Artificial generation of centromeres and kinetochores to understand their structure and function

Tetsuya Hori, Tatsuo Fukagawa

Experimental Cell Research　Vol. 389　No. 2　p. 111898-111898　2020/04　Research paper (scientific journal)

Dynamics of kinetochore structure and its regulations during mitotic progression.

Masatoshi Hara, Tatsuo Fukagawa

Cellular and molecular life sciences : CMLS　2020/02/12　Research paper (scientific journal)

Cryo-EM Structures of Centromeric Tri-nucleosomes Containing a Central CENP-A Nucleosome.

Yoshimasa Takizawa, Cheng-Han Ho, Hiroaki Tachiwana, Hideyuki Matsunami, Wataru Kobayashi, Midori Suzuki, Yasuhiro Arimura, Tetsuya Hori, Tatsuo Fukagawa, Melanie D Ohi, Matthias Wolf, Hitoshi Kurumizaka

Structure (London, England : 1993)　Vol. 28　No. 1　p. 44-53　2020/01/07

CDK1-mediated CENP-C phosphorylation modulates CENP-A binding and mitotic kinetochore localization.

Reito Watanabe, Masatoshi Hara, Ei-Ichi Okumura, Solène Hervé, Daniele Fachinetti, Mariko Ariyoshi, Tatsuo Fukagawa

The Journal of cell biology　Vol. 218　No. 12　p. 4042-4062　2019/12/02　Research paper (scientific journal)

The CENP-A centromere targeting domain facilitates H4K20 monomethylation in the nucleosome by structural polymorphism

Yasuhiro Arimura, Hiroaki Tachiwana, Hiroki Takagi, Tetsuya Hori, Hiroshi Kimura, Tatsuo Fukagawa, Hitoshi Kurumizaka

Nature Communications　Vol. 10　No. 1　2019/12/01　Research paper (scientific journal)

Where is the right path heading from the centromere to spindle microtubules?

Hara M, Fukagawa T

Cell cycle (Georgetown, Tex.)　Vol. 18　No. 11　p. 1199-1211　2019/06

Centromere maintenance during DNA replication.

Hara M, Fukagawa T

Nature cell biology　Vol. 21　No. 6　p. 669-671　2019/06

Live imaging of marked chromosome regions reveals their dynamic resolution and compaction in mitosis.

Eykelenboom JK, Gierliński M, Yue Z, Hegarat N, Pollard H, Fukagawa T, Hochegger H, Tanaka TU

The Journal of cell biology　Vol. 218　No. 5　p. 1531-1552　2019/03

3D genomic architecture reveals that neocentromeres associate with heterochromatin regions

Kohei Nishimura, Masataka Komiya, Tetsuya Hori, Takehiko Itoh, Tatsuo Fukagawa

Journal of Cell Biology　Vol. 218　No. 1　p. 134-149　2019/01/01　Research paper (scientific journal)

Publisher Correction: Multiple phosphorylations control recruitment of the KMN network onto kinetochores.

Hara M, Ariyoshi M, Okumura EI, Hori T, Fukagawa T

Nature cell biology　Vol. 20　No. 12　2018/12

Multiple phosphorylations control recruitment of the KMN network onto kinetochores

Masatoshi Hara, Mariko Ariyoshi, Ei ichi Okumura, Tetsuya Hori, Tatsuo Fukagawa

Nature Cell Biology　Vol. 20　No. 12　p. 1378-1388　2018/12/01　Research paper (scientific journal)

Kinetochore assembly and disassembly during mitotic entry and exit

Masatoshi Hara, Tatsuo Fukagawa

Current Opinion in Cell Biology　Vol. 52　p. 73-81　2018/06/01

Site-specific cleavage by topoisomerase 2: A mark of the core centromere

Walter E. Mills, Jennifer M. Spence, Tatsuo Fukagawa, Christine J. Farr

International Journal of Molecular Sciences　Vol. 19　No. 2　2018/02/10　Research paper (scientific journal)

CENP-R acts bilaterally as a tumor suppressor and as an oncogene in the two-stage skin carcinogenesis model.

Kazuhiro Okumura, Naoko Kagawa, Megumi Saito, Yasuhiro Yoshizawa, Haruka Munakata, Eriko Isogai, Tatsuo Fukagawa, Yuichi Wakabayashi

Cancer science　Vol. 108　No. 11　p. 2142-2148　2017/11　Research paper (scientific journal)

An efficient method to generate conditional knockout cell lines for essential genes by combination of auxin-inducible degron tag and CRISPR/Cas9

Kohei Nishimura, Tatsuo Fukagawa

CHROMOSOME RESEARCH　Vol. 25　No. 3-4　p. 253-260　2017/10　Research paper (scientific journal)

Association of M18BP1/KNL2 with CENP-A Nucleosome Is Essential for Centromere Formation in Non-mammalian Vertebrates

Tetsuya Hori, Wei-Hao Shang, Masatoshi Hara, Mariko Ariyoshi, Yasuhiro Arimura, Risa Fujita, Hitoshi Kurumizaka, Tatsuo Fukagawa

DEVELOPMENTAL CELL　Vol. 42　No. 2　p. 181-+　2017/07　Research paper (scientific journal)

Stepwise unfolding supports a subunit model for vertebrate kinetochores

Giulia Vargiu, Alexandr A. Makarov, James Allan, Tatsuo Fukagawa, Daniel G. Booth, William C. Earnshaw

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA　Vol. 114　No. 12　p. 3133-3138　2017/03　Research paper (scientific journal)

Critical histone post-translational modifications for centromere function and propagation

Tatsuo Fukagawa

CELL CYCLE　Vol. 16　No. 13　p. 1259-1265　2017

Critical Foundation of the Kinetochore: The Constitutive Centromere-Associated Network (CCAN).

Hara M, Fukagawa T

Progress in molecular and subcellular biology　Vol. 56　p. 29-57　2017

Constitutive centromere-associated network controls centromere drift in vertebrate cells

Tetsuya Hori, Naoko Kagawa, Atsushi Toyoda, Asao Fujiyama, Sadahiko Misu, Norikazu Monma, Fumiaki Makino, Kazuho Ikeo, Tatsuo Fukagawa

JOURNAL OF CELL BIOLOGY　Vol. 216　No. 1　p. 101-113　2017/01　Research paper (scientific journal)

Acetylation of histone H4 lysine 5 and 12 is required for CENP-A deposition into centromeres.

Shang WH, Hori T, Westhorpe FG, Godek KM, Toyoda A, Misu S, Monma N, Ikeo K, Carroll CW, Takami Y, Fujiyama A, Kimura H, Straight AF, Fukagawa T

Nature communications　Vol. 7　2016/11

Acetylation of histone H4 lysine 5 and 12 is required for CENP-A deposition into centromeres

Wei-Hao Shang, Tetsuya Hori, Frederick G. Westhorpe, Kristina M. Godek, Atsushi Toyoda, Sadahiko Misu, Norikazu Monma, Kazuho Ikeo, Christopher W. Carroll, Yasunari Takami, Asao Fujiyama, Hiroshi Kimura, Aaron F. Straight, Tatsuo Fukagawa

NATURE COMMUNICATIONS　Vol. 7　2016/11　Research paper (scientific journal)

Chromatin determinants of the inner-centromere rely on replication factors with functions that impart cohesion

Takuya Abe, Ryotaro Kawasumi, Hiroshi Arakawa, Tetsuya Hori, Katsuhiko Shirahige, Ana Losada, Tatsuo Fukagawa, Dana Branzei

ONCOTARGET　Vol. 7　No. 42　p. 67934-67947　2016/10　Research paper (scientific journal)

Kinetochore assembly and function through the cell cycle

Harsh Nagpal, Tatsuo Fukagawa

CHROMOSOMA　Vol. 125　No. 4　p. 645-659　2016/09

Chicken rRNA Gene Cluster Structure

Alexander G. Dyomin, Elena I. Koshel, Artem M. Kiselev, Alsu F. Saifitdinova, Svetlana A. Galkina, Tatsuo Fukagawa, Anna A. Kostareva, Elena R. Gaginskaya

PLOS ONE　Vol. 11　No. 6　2016/06　Research paper (scientific journal)

RbAp48 is essential for viability of vertebrate cells and plays a role in chromosome stability

Pasjan Satrimafitrah, Hirak Kumar Barman, Ahyar Ahmad, Hideki Nishitoh, Tatsuo Nakayama, Tatsuo Fukagawa, Yasunari Takami

CHROMOSOME RESEARCH　Vol. 24　No. 2　p. 161-173　2016/05　Research paper (scientific journal)

Biochemical and Structural Analysis of Kinetochore Histone-Fold Complexes.

Nishino T, Fukagawa T

Methods in molecular biology (Clifton, N.J.)　Vol. 1413　p. 135-146　2016/04

Genetic complementation analysis showed distinct contributions of the N-terminal tail of H2A.Z to epigenetic regulations

Masayuki Kusakabe, Hiroyuki Oku, Ryo Matsuda, Tetsuya Hori, Akihiko Muto, Kazuhiko Igarashi, Tatsuo Fukagawa, Masahiko Harata

GENES TO CELLS　Vol. 21　No. 2　p. 122-135　2016/02　Research paper (scientific journal)

Centromeric chromatin and kinetochore assembly in vertebrate cells

Tatsuo Fukagawa

DNA Replication, Recombination, and Repair: Molecular Mechanisms and Pathology　p. 365-387　2016/01/01　Part of collection (book)

Chromatin binding of RCC1 during mitosis is important for its nuclear localization in interphase

Maiko Furuta, Tetsuya Hori, Tatsuo Fukagawa

MOLECULAR BIOLOGY OF THE CELL　Vol. 27　No. 2　p. 371-381　2016/01　Research paper (scientific journal)

Auxin/AID versus conventional knockouts: distinguishing the roles of CENP-T/W in mitotic kinetochore assembly and stability

Laura Wood, Daniel G. Booth, Giulia Vargiu, Shinya Ohta, Flavia Delima Alves, Kumiko Samejima, Tatsuo Fukagawa, Juri Rappsilber, William C. Earnshaw

OPEN BIOLOGY　Vol. 6　No. 1　2016/01　Research paper (scientific journal)

Biochemical and Structural Analysis of Kinetochore Histone-Fold Complexes.

Nishino T, Fukagawa T

Methods in molecular biology (Clifton, N.J.)　Vol. 1413　p. 135-146　2016

Whole-proteome genetic analysis of dependencies in assembly of a vertebrate kinetochore

Itaru Samejima, Christos Spanos, Flavia de Lima Alves, Tetsuya Hori, Marinela Perpelescu, Juan Zou, Juri Rappsilber, Tatsuo Fukagawa, William C. Earnshaw

JOURNAL OF CELL BIOLOGY　Vol. 211　No. 6　p. 1141-1156　2015/12　Research paper (scientific journal)

A new Xist allele driven by a constitutively active promoter is dominated by Xist locus environment and exhibits the parent-of-origin effects

Yuko Amakawa, Yuka Sakata, Yuko Hoki, Satoru Arata, Seiji Shioda, Tatsuo Fukagawa, Hiroyuki Sasaki, Takashi Sado

DEVELOPMENT　Vol. 142　No. 24　p. 4299-4308　2015/12　Research paper (scientific journal)

Dynamic changes in CCAN organization through CENP-C during cell-cycle progression

Nagpal H, Hori T, Furukawa A, Sugase K, Osakabe A, Kurumizaka H, Fukagawa T

Mol Cell Biol　Vol. 26　No. 21　p. 3768-3776　2015/11　Research paper (scientific journal)

HJURP is involved in the expansion of centromeric chromatin

Marinela Perpelescu, Tetsuya Hori, Atsushi Toyoda, Sadahiko Misu, Norikazu Monma, Kazuho Ikeo, Chikashi Obuse, Asao Fujiyama, Tatsuo Fukagawa

MOLECULAR BIOLOGY OF THE CELL　Vol. 26　No. 15　p. 2742-2754　2015/08　Research paper (scientific journal)

Cell Division: A New Role for the Kinetochore in Central Spindle Assembly

Tatsuo Fukagawa

CURRENT BIOLOGY　Vol. 25　No. 13　p. R554-R557　2015/06

CENP-32 is required to maintain centrosomal dominance in bipolar spindle assembly

Shinya Ohta, Laura Wood, Iyo Toramoto, Ken-Ichi Yagyu, Tatsuo Fukagawa, William C. Earnshaw

MOLECULAR BIOLOGY OF THE CELL　Vol. 26　No. 7　p. 1225-1237　2015/04　Research paper (scientific journal)

Tatsuo Fukagawa

Tatsuo Fukagawa

Current Biology　Vol. 25　No. 21　p. R1021-R1023　2015

Crystal structure and stable property of the cancer-associated heterotypic nucleosome containing CENP-A and H3.3

Yasuhiro Arimura, Kazuyoshi Shirayama, Naoki Horikoshi, Risa Fujita, Hiroyuki Taguchi, Wataru Kagawa, Tatsuo Fukagawa, Genevieve Almouzni, Hitoshi Kurumizaka

SCIENTIFIC REPORTS　Vol. 4　2014/11　Research paper (scientific journal)

Neocentromeres

Tatsuo Fukagawa, William C. Earnshaw

CURRENT BIOLOGY　Vol. 24　No. 19　p. R946-R947　2014/10

The CENP-O complex requirement varies among different cell types

Naoko Kagawa, Tetsuya Hori, Yuko Hoki, Osamu Hosoya, Kimiko Tsutsui, Yumiko Saga, Takashi Sado, Tatsuo Fukagawa

CHROMOSOME RESEARCH　Vol. 22　No. 3　p. 293-303　2014/09　Research paper (scientific journal)

The Centromere: Chromatin Foundation for the Kinetochore Machinery

Tatsuo Fukagawa, William C. Earnshaw

DEVELOPMENTAL CELL　Vol. 30　No. 5　p. 497-509　2014/09

Reorganization of damaged chromatin by the exchange of histone variant H2A.Z-2

Ikuno Nishibuchi, Hidekazu Suzuki, Aiko Kinomura, Jiying Sun, Ning-Ang Liu, Yasunori Horikoshi, Hiroki Shima, Masayuki Kusakabe, Masahiko Harata, Tatsuo Fukagawa, Tsuyoshi Ikura, Takafumi Ishida, Yasushi Nagata, Satoshi Tashiro

International Journal of Radiation Oncology Biology Physics　Vol. 89　No. 4　p. 736-744　2014/07/15　Research paper (scientific journal)

Histone H4 Lys 20 Monomethylation of the CENP-A Nucleosome Is Essential for Kinetochore Assembly

Tetsuya Hori, Wei-Hao Shang, Atsushi Toyoda, Sadahiko Misu, Norikazu Monma, Kazuho Ikeo, Oscar Molina, Giulia Vargiu, Asao Fujiyama, Hiroshi Kimura, William C. Earnshaw, Tatsuo Fukagawa

DEVELOPMENTAL CELL　Vol. 29　No. 6　p. 740-749　2014/06　Research paper (scientific journal)

The histone-fold complex MHF is remodeled by FANCM to recognize branched DNA and protect genome stability

David Fox, Zhijiang Yan, Chen Ling, Ye Zhao, Duck-Yeon Lee, Tatsuo Fukagawa, Wei Yang, Weidong Wang

CELL RESEARCH　Vol. 24　No. 5　p. 560-575　2014/05　Research paper (scientific journal)

Meiosis-specific cohesin mediates homolog recognition in mouse spermatocytes

Kei-ichiro Ishiguro, Jihye Kim, Hiroki Shibuya, Abrahan Hernandez-Hernandez, Aussie Suzuki, Tatsuo Fukagawa, Go Shioi, Hiroshi Kiyonari, Xin C. Li, John Schimenti, Christer Hoog, Yoshinori Watanabe

GENES & DEVELOPMENT　Vol. 28　No. 6　p. 594-607　2014/03　Research paper (scientific journal)

The centromeric nucleosome-like CENP-T-W-S-X complex induces positive supercoils into DNA

Takeuchi, Kozo, Nishino, Tatsuya, Mayanagi, Kouta, Horikoshi, Naoki, Osakabe, Akihisa, Tachiwana, Hiroaki, Hori, Tetsuya, Kurumizaka, Hitoshi, Fukagawa, Tatsuo

Nucleic acids research　Vol. 42　No. 3　p. 1644-1655　2014/02　Research paper (scientific journal)

Speciation Mediated by Centromeres

Tatsuo Fukagawa

DEVELOPMENTAL CELL　Vol. 27　No. 4　p. 367-368　2013/11

Structure-Specific Endonucleases Xpf and Mus81 Play Overlapping but Essential Roles in DNA Repair by Homologous Recombination

Koji Kikuchi, Takeo Narita, Van T. Pham, Junko Iijima, Kouji Hirota, Islam Shamima Keka, Katsuya Okawa, Tetsuya Hori, Tatsuo Fukagawa, Jeroen Essers, Roland Kanaar, Matthew C. Whitby, Kaoru Sugasawa, Yoshihito Taniguchi, Katsumi Kitagawa, Shunichi Takeda

CANCER RESEARCH　Vol. 73　No. 14　p. 4362-4371　2013/07　Research paper (scientific journal)

Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant

W. C. Earnshaw, R. C. Allshire, B. E. Black, K. Bloom, B. R. Brinkley, W. Brown, I. M. Cheeseman, K. H. A. Choo, G. P. Copenhaver, J. G. DeLuca, A. Desai, S. Diekmann, S. Erhardt, M. Fitzgerald-Hayes, D. Foltz, T. Fukagawa, R. Gassmann, D. W. Gerlich, D. M. Glover, G. J. Gorbsky, S. C. Harrison, P. Heun, T. Hirota, L. E. T. Jansen, G. Karpen, G. J. P. L. Kops, M. A. Lampson, S. M. Lens, A. Losada, K. Luger, H. Maiato, P. S. Maddox, R. L. Margolis, H. Masumoto, A. D. McAinsh, B. G. Mellone, P. Meraldi, A. Musacchio, K. Oegema, R. J. O'Neill, E. D. Salmon, K. C. Scott, A. F. Straight, P. T. Stukenberg, B. A. Sullivan, K. F. Sullivan, C. E. Sunkel, J. R. Swedlow, C. E. Walczak, P. E. Warburton, S. Westermann, H. F. Willard, L. Wordeman, M. Yanagida, T. J. Yen, K. Yoda, D. W. Cleveland

CHROMOSOME RESEARCH　Vol. 21　No. 2　p. 101-106　2013/04　Research paper (scientific journal)

Vertebrate Spt2 is a novel nucleolar histone chaperone that assists in ribosomal DNA transcription

Akihisa Osakabe, Hiroaki Tachiwana, Motoki Takaku, Tetsuya Hori, Chikashi Obuse, Hiroshi Kimura, Tatsuo Fukagawa, Hitoshi Kurumizaka

JOURNAL OF CELL SCIENCE　Vol. 126　No. 6　p. 1323-1332　2013/03　Research paper (scientific journal)

Chromosome Engineering Allows the Efficient Isolation of Vertebrate Neocentromeres

Wei-Hao Shang, Tetsuya Hori, Nuno M. C. Martins, Atsushi Toyoda, Sadahiko Misu, Norikazu Monma, Ichiro Hiratani, Kazuhiro Maeshima, Kazuho Ikeo, Asao Fujiyama, Hiroshi Kimura, William C. Earnshaw, Tatsuo Fukagawa

DEVELOPMENTAL CELL　Vol. 24　No. 6　p. 635-648　2013/03　Research paper (scientific journal)

CENP-T provides a structural platform for outer kinetochore assembly

Tatsuya Nishino, Florencia Rago, Tetsuya Hori, Kentaro Tomii, Iain M. Cheeseman, Tatsuo Fukagawa

EMBO JOURNAL　Vol. 32　No. 3　p. 424-436　2013/02　Research paper (scientific journal)

The CCAN recruits CENP-A to the centromere and forms the structural core for kinetochore assembly

Tetsuya Hori, Wei-Hao Shang, Kozo Takeuchi, Tatsuo Fukagawa

JOURNAL OF CELL BIOLOGY　Vol. 200　No. 1　p. 45-60　2013/01　Research paper (scientific journal)

High-resolution mapping and transcriptional activity analysis of chicken centromere sequences on giant lampbrush chromosomes

Alla Krasikova, Tatsuo Fukagawa, Anna Zlotina

CHROMOSOME RESEARCH　Vol. 20　No. 8　p. 995-1008　2012/12　Research paper (scientific journal)

The actin family member Arp6 and the histone variant H2A.Z are required for spatial positioning of chromatin in chicken cell nuclei

Eri Ohfuchi Maruyama, Tetsuya Hori, Hideyuki Tanabe, Hiroshi Kitamura, Ryo Matsuda, Shigenobu Tone, Pavel Hozak, Felix A. Habermann, Johann von Hase, Christoph Cremer, Tatsuo Fukagawa, Masahiko Harata

JOURNAL OF CELL SCIENCE　Vol. 125　No. 16　p. 3739-3744　2012/08　Research paper (scientific journal)

Mcm8 and Mcm9 Form a Complex that Functions in Homologous Recombination Repair Induced by DNA Interstrand Cross links

Kohei Nishimura, Masamichi Ishiai, Kazuki Horikawa, Tatsuo Fukagawa, Minoru Takata, Haruhiko Takisawa, Masato T. Kanemaki

MOLECULAR CELL　Vol. 47　No. 4　p. 511-522　2012/08　Research paper (scientific journal)

Molecular architecture of vertebrate kinetochores

Kozo Takeuchi, Tatsuo Fukagawa

EXPERIMENTAL CELL RESEARCH　Vol. 318　No. 12　p. 1367-1374　2012/07

Formation of a centromere-specific chromatin structure

Tatsuo Fukagawa

EPIGENETICS　Vol. 7　No. 7　p. 672-675　2012/07　Research paper (scientific journal)

Establishment of the vertebrate kinetochores

Tetsuya Hori, Tatsuo Fukagawa

CHROMOSOME RESEARCH　Vol. 20　No. 5　p. 547-561　2012/07　Research paper (scientific journal)

CENP-T-W-S-X Forms a Unique Centromeric Chromatin Structure with a Histone-like Fold

Tatsuya Nishino, Kozo Takeuchi, Karen E. Gascoigne, Aussie Suzuki, Tetsuya Hori, Takuji Oyama, Kosuke Morikawa, Iain M. Cheeseman, Tatsuo Fukagawa

CELL　Vol. 148　No. 3　p. 487-501　2012/02　Research paper (scientific journal)

The ABCs of CENPs

Marinela Perpelescu, Tatsuo Fukagawa

CHROMOSOMA　Vol. 120　No. 5　p. 425-446　2011/10

Spindle microtubules generate tension-dependent changes in the distribution of inner kinetochore proteins

Aussie Suzuki, Tetsuya Hori, Tatsuya Nishino, Jiro Usukura, Atsushi Miyagi, Kosuke Morikawa, Tatsuo Fukagawa

JOURNAL OF CELL BIOLOGY　Vol. 193　No. 1　p. 125-140　2011/04　Research paper (scientific journal)

Induced Ectopic Kinetochore Assembly Bypasses the Requirement for CENP-A Nucleosomes

Karen E. Gascoigne, Kozo Takeuchi, Aussie Suzuki, Tetsuya Hori, Tatsuo Fukagawa, Iain M. Cheeseman

CELL　Vol. 145　No. 3　p. 410-422　2011/04　Research paper (scientific journal)

Cell biological analysis of DT40 knockout cell lines for cell-cycle genes

Aussie Suzuki, Tatsuo Fukagawa

Current Protocols in Cell Biology　Vol. Chapter 8　No. 50　2011　Research paper (scientific journal)

Aurora B kinase controls the targeting of the Astrin-SKAP complex to bioriented kinetochores

Jens C. Schmidt, Tomomi Kiyomitsu, Tetsuya Hori, Chelsea B. Backer, Tatsuo Fukagawa, Iain M. Cheeseman

JOURNAL OF CELL BIOLOGY　Vol. 191　No. 2　p. 269-280　2010/10　Research paper (scientific journal)

Chickens possess centromeres with both extended tandem repeats and short non-tandem-repetitive sequences

Wei-Hao Shang, Tetsuya Hori, Atsushi Toyoda, Jun Kato, Kris Popendorf, Yasubumi Sakakibara, Asao Fujiyama, Tatsuo Fukagawa

GENOME RESEARCH　Vol. 20　No. 9　p. 1219-1228　2010/09　Research paper (scientific journal)

The Protein Composition of Mitotic Chromosomes Determined Using Multiclassifier Combinatorial Proteomics

Shinya Ohta, Jimi-Carlo Bukowski-Wills, Luis Sanchez-Pulido, Flavia de Lima Alves, Laura Wood, Zhuo A. Chen, Melpi Platani, Lutz Fischer, Damien F. Hudson, Chris P. Ponting, Tatsuo Fukagawa, William C. Earnshaw, Juri Rappsilber

CELL　Vol. 142　No. 5　p. 810-821　2010/09　Research paper (scientific journal)

KRAB Zinc Finger Protein ZNF382 Is a Proapoptotic Tumor Suppressor That Represses Multiple Oncogenes and Is Commonly Silenced in Multiple Carcinomas

Yingduan Cheng, Hua Geng, Suk Hang Cheng, Pei Liang, Yan Bai, Jisheng Li, Gopesh Srivastava, Margaret H. L. Ng, Tatsuo Fukagawa, Xiushan Wu, Anthony T. C. Chan, Qian Tao

CANCER RESEARCH　Vol. 70　No. 16　p. 6516-6526　2010/08　Research paper (scientific journal)

Identification and characterization of the two isoforms of the vertebrate H2A.Z histone variant

Ryo Matsuda, Tetsuya Hori, Hiroshi Kitamura, Kozo Takeuchi, Tatsuo Fukagawa, Masahiko Harata

NUCLEIC ACIDS RESEARCH　Vol. 38　No. 13　p. 4263-4273　2010/07　Research paper (scientific journal)

A super-resolution map of the vertebrate kinetochore

Susana Abreu Ribeiro, Paola Vagnarelli, Yimin Dong, Tetsuya Hori, Bruce F. McEwen, Tatsuo Fukagawa, Cristina Flors, William C. Earnshaw

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA　Vol. 107　No. 23　p. 10484-10489　2010/06　Research paper (scientific journal)

Vertebrate kinetochore protein architecture: protein copy number

Katherine Johnston, Ajit Joglekar, Tetsuya Hori, Aussie Suzuki, Tatsuo Fukagawa, E. D. Salmon

JOURNAL OF CELL BIOLOGY　Vol. 189　No. 6　p. 937-943　2010/06　Research paper (scientific journal)

Aurora B Phosphorylates Spatially Distinct Targets to Differentially Regulate the Kinetochore-Microtubule Interface

Julie P. I. Welburn, Mathijs Vleugel, Dan Liu, John R. Yates, Michael A. Lampson, Tatsuo Fukagawa, Iain M. Cheeseman

MOLECULAR CELL　Vol. 38　No. 3　p. 383-392　2010/05　Research paper (scientific journal)

Regulated targeting of protein phosphatase 1 to the outer kinetochore by KNL1 opposes Aurora B kinase

Dan Liu, Mathijs Vleugel, Chelsea B. Backer, Tetsuya Hori, Tatsuo Fukagawa, Iain M. Cheeseman, Michael A. Lampson

JOURNAL OF CELL BIOLOGY　Vol. 188　No. 6　p. 809-820　2010/03　Research paper (scientific journal)

An auxin-based degron system for the rapid depletion of proteins in nonplant cells

Kohei Nishimura, Tatsuo Fukagawa, Haruhiko Takisawa, Tatsuo Kakimoto, Masato Kanemaki

NATURE METHODS　Vol. 6　No. 12　p. 917-U78　2009/12　Research paper (scientific journal)

INCENP-aurora B interactions modulate kinase activity and chromosome passenger complex localization

Zhenjie Xu, Hiromi Ogawa, Paola Vagnarelli, Jan H. Bergmann, Damien F. Hudson, Sandrine Ruchaud, Tatsuo Fukagawa, William C. Earnshaw, Kumiko Samejima

JOURNAL OF CELL BIOLOGY　Vol. 187　No. 5　p. 637-653　2009/11　Research paper (scientific journal)

CENP-H-containing Complex Facilitates Centromere Deposition of CENP-A in Cooperation with FACT and CHD1

Masahiro Okada, Katsuya Okawa, Toshiaki Isobe, Tatsuo Fukagawa

MOLECULAR BIOLOGY OF THE CELL　Vol. 20　No. 18　p. 3986-3995　2009/09　Research paper (scientific journal)

[DNA-binding proteins are involved in establishment of centromere chromatin structure coordinately with centromere specific histone variant, CENP-A].

Hori T, Fukagawa T

Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme　Vol. 54　No. 10　p. 1276-1283　2009/08

The CENP-S complex is essential for the stable assembly of outer kinetochore structure

Miho Amano, Aussie Suzuki, Tetsuya Hori, Chelsea Backer, Katsuya Okawa, Iain M. Cheeseman, Tatsuo Fukagawa

JOURNAL OF CELL BIOLOGY　Vol. 186　No. 2　p. 173-182　2009/07　Research paper (scientific journal)

Two Distinct Repeat Sequences of Nup98 Nucleoporins Characterize Dual Nuclei in the Binucleated Ciliate Tetrahymena

Masaaki Iwamoto, Chie Mori, Tomoko Kojidani, Fumihide Bunai, Tetsuya Hori, Tatsuo Fukagawa, Yasushi Hiraoka, Tokuko Haraguchi

CURRENT BIOLOGY　Vol. 19　No. 10　p. 843-847　2009/05　Research paper (scientific journal)

A Rac GTPase-Activating Protein, MgcRacGAP, Is a Nuclear Localizing Signal-Containing Nuclear Chaperone in the Activation of STAT Transcription Factors

Toshiyuki Kawashima, Ying Chun Bao, Yukinori Minoshima, Yasushi Nomura, Tomonori Hatori, Tetsuya Hori, Tatsuo Fukagawa, Toshiyuki Fukada, Noriko Takahashi, Tetsuya Nosaka, Makoto Inoue, Tomohiro Sato, Mutsuko Kukimoto-Niino, Mikako Shirouzu, Shigeyuki Yokoyama, Toshio Kitamura

MOLECULAR AND CELLULAR BIOLOGY　Vol. 29　No. 7　p. 1796-1813　2009/04　Research paper (scientific journal)

Cohesin Associates with Spindle Poles in a Mitosis-specific Manner and Functions in Spindle Assembly in Vertebrate Cells

Xiangduo Kong, Alexander R. Ball, Eiichiro Sonoda, Jie Feng, Shunichi Takeda, Tatsuo Fukagawa, Tim J. Yen, Kyoko Yokomori

MOLECULAR BIOLOGY OF THE CELL　Vol. 20　No. 5　p. 1289-1301　2009/03　Research paper (scientific journal)

Role of Glucocorticoid Receptor in the Regulation of Cellular Sensitivity to Irinotecan Hydrochloride

Takanori Akagi, Tatsuo Fukagawa, Yuki Kage, Hideto To, Naoya Matsunaga, Satoru Koyanagi, Akiko Uchida, Asuka Fujii, Hideo Iba, Toshimichi Ikemura, Hironori Aramaki, Shun Higuchi, Shigehiro Ohdo

JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 109　No. 2　p. 265-274　2009/02　Research paper (scientific journal)

Kinetochore composition, formation, and organization

Tatsuo Fukagawa, Peter De Wulf

The Kinetochore: From Molecular Discoveries to Cancer Therapy　p. 133-191　2009　Part of collection (book)

CCAN Makes Multiple Contacts with Centromeric DNA to Provide Distinct Pathways to the Outer Kinetochore

Tetsuya Hori, Miho Amano, Aussie Suzuki, Chelsea B. Backer, Julie P. Welburn, Yimin Dong, Bruce F. McEwen, Wei-Hao Shang, Emiko Suzuki, Katsuya Okawa, Iain M. Cheeseman, Tatsuo Fukagawa

CELL　Vol. 135　No. 6　p. 1039-1052　2008/12　Research paper (scientific journal)

CENP-O class proteins form a stable complex and are required for proper kinetochore function

Tetsuya Hori, Masahiro Okada, Katsumi Maenaka, Tatsuo Fukagawa

MOLECULAR BIOLOGY OF THE CELL　Vol. 19　No. 3　p. 843-854　2008/03　Research paper (scientific journal)

KNL1 and the CENP-H/I/K complex coordinately direct kinetochore assembly in vertebrates

Iain M. Cheeseman, Tetsuya Hori, Tatsuo Fukagawa, Arshad Desai

MOLECULAR BIOLOGY OF THE CELL　Vol. 19　No. 2　p. 587-594　2008/02　Research paper (scientific journal)

The kinetochore and spindle checkpoint in vertebrate cells

Tatsuo Fukagawa

FRONTIERS IN BIOSCIENCE-LANDMARK　Vol. 13　p. 2705-2713　2008/01　Research paper (scientific journal)

CENP-C is involved in chromosome segregation, mitotic checkpoint function, and kinetochore assembly

Mi-Sun Kwon, Tetsuya Hori, Masahiro Okada, Tatsuo Fukagawa

MOLECULAR BIOLOGY OF THE CELL　Vol. 18　No. 6　p. 2155-2168　2007/06　Research paper (scientific journal)

The human Nup107-160 nuclear pore subcomplex contributes to proper kinetochore functions

Michela Zuccolo, Annabelle Alves, Vincent Galy, Stephanie Bolhy, Etienne Formstecher, Victor Racine, Jean-Baptiste Sibarita, Tatsuo Fukagawa, Ramin Shiekhattar, Tim Yen, Valerie Doye

EMBO JOURNAL　Vol. 26　No. 7　p. 1853-1864　2007/04　Research paper (scientific journal)

Essential role of chromatin assembly factor-1-mediated rapid nucleosome assembly for DNA replication and cell division in vertebrate cells

Yasunari Takami, Tatsuya Ono, Tatsuo Fukagawa, Kei-ichi Shibahara, Tatsuo Nakayama

MOLECULAR BIOLOGY OF THE CELL　Vol. 18　No. 1　p. 129-141　2007/01　Research paper (scientific journal)

A novel histone exchange factor, protein phosphatase 2C gamma mediates the exchange and dephosphorylation of H2A-H2B

Hiroshi Kimura, Nanako Takizawa, Eric Allemand, Tetsuya Hori, Francisco J. Iborra, Naohito Nozaki, Michiko Muraki, Masatoshi Hagiwara, Adrian R. Krainer, Tatsuo Fukagawa, Katsuya Okawa

JOURNAL OF CELL BIOLOGY　Vol. 175　No. 3　p. 389-400　2006/11　Research paper (scientific journal)

Asf1 is required for viability and chromatin assembly during DNA replication in vertebrate cells

F Sanematsu, Y Takami, HK Barman, T Fukagawa, T Ono, KI Shibahara, T Nakayama

JOURNAL OF BIOLOGICAL CHEMISTRY　Vol. 281　No. 19　p. 13817-13827　2006/05　Research paper (scientific journal)

The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres

M Okada, IM Cheeseman, T Hori, K Okawa, McLeod, IX, Yates, JR, A Desai, T Fukagawa

NATURE CELL BIOLOGY　Vol. 8　No. 5　p. 446-U61　2006/05　Research paper (scientific journal)

The human Mis 12 complex is required for kinetochore assembly and proper chromosome segregation

SL Kline, IM Cheeseman, T Hori, T Fukagawa, A Desai

JOURNAL OF CELL BIOLOGY　Vol. 173　No. 1　p. 9-17　2006/04　Research paper (scientific journal)

[Dynamics of the kinetochore proteins which target to the chromatin of centromeres].

Hori T, Fukagawa T

Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme　Vol. 51　No. 4　p. 326-334　2006/04

Molecular mechanism for kinetochore assembly in vertebrate cells

Tetsuya Hori, Masahiro Okada, Tatsuo Fukagawa

DNA STRUCTURE, CHROMATIN AND GENE EXPRESSION, 2006　p. 237-252　2006　Research paper (international conference proceedings)

The DT40 system as a tool for analyzing kinetochore assembly.

Okada M, Hori T, Fukagawa T

Sub-cellular biochemistry　Vol. 40　p. 91-106　2006

The constitutive centromere component CENP-50 is required for recovery from spindle damage

Y Minoshima, T Hori, M Okada, H Kimura, T Haraguchi, Y Hiraoka, YC Bao, T Kawashima, T Kitamura, T Fukagawa

MOLECULAR AND CELLULAR BIOLOGY　Vol. 25　No. 23　p. 10315-10328　2005/12　Research paper (scientific journal)

Cell-cycle-dependent pharmacology of methotrexate in HL-60

A Yamauchi, T Ichimiya, K Inoue, Y Taguchi, N Matsunaga, S Koyanagi, T Fukagawa, H Aramaki, S Higuchi, S Ohdo

JOURNAL OF PHARMACOLOGICAL SCIENCES　Vol. 99　No. 4　p. 335-341　2005/12　Research paper (scientific journal)

CENP-A is required for accurate chromosome segregation and sustained kinetochore association of BubR1

Regnier, V, P Vagnarelli, T Fukagawa, T Zerjal, E Burns, D Trouche, W Earnshaw, W Brown

MOLECULAR AND CELLULAR BIOLOGY　Vol. 25　No. 10　p. 3967-3981　2005/05　Research paper (scientific journal)

The functional region of CENP-H interacts with the Nuf2 complex that localizes to centromere during mitosis

Y Mikami, T Hori, H Kimura, T Fukagawa

MOLECULAR AND CELLULAR BIOLOGY　Vol. 25　No. 5　p. 1958-1970　2005/03　Research paper (scientific journal)

Efficient large-scale protein production of larvae and pupae of silkworm by Bombyx mori nuclear polyhedrosis virus bacmid system

T Motohashi, T Shimojima, T Fukagawa, K Maenaka, EY Park

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS　Vol. 326　No. 3　p. 564-569　2005/01　Research paper (scientific journal)

Dicer is essential for formation of the heterochromatin structure in vertebrate cells

T Fukagawa, M Nogami, M Yoshikawa, M Ikeno, T Okazaki, Y Takami, T Nakayama, M Oshimura

NATURE CELL BIOLOGY　Vol. 6　No. 8　p. 784-791　2004/08　Research paper (scientific journal)

Assembly of kinetochores in vertebrate cells

T Fukagawa

EXPERIMENTAL CELL RESEARCH　Vol. 296　No. 1　p. 21-27　2004/05

Centromere DNA, proteins and kinetochore assembly in vertebrate cells

T Fukagawa

CHROMOSOME RESEARCH　Vol. 12　No. 6　p. 557-567　2004　Research paper (scientific journal)

Characterization of chicken CENP-A and comparative sequence analysis of vertebrate centromere-specific histone H3-like proteins

Regnier, V, J Novelli, T Fukagawa, P Vagnarelli, W Brown

GENE　Vol. 316　p. 39-46　2003/10　Research paper (scientific journal)

Dynamic behavior of Nuf2-Hec1 complex that localizes to the centrosome and centromere and is essential for mitotic progression in vertebrate cells

Tetsuya Hori, Tokuko Haraguchi, Yasushi Hiraoka, Hiroshi Kimura, Tatsuo Fukagawa

Journal of Cell Science　Vol. 116　No. 16　p. 3347-3362　2003/08/15

Ubc9 is essential for viability of higher eukaryotic cells

T Hayashi, M Seki, D Maeda, WS Wang, Y Kawabe, T Seki, H Saitoh, T Fukagawa, H Yagi, T Enomoto

EXPERIMENTAL CELL RESEARCH　Vol. 280　No. 2　p. 212-221　2002/11　Research paper (scientific journal)

Co-localization of centromere activity, proteins and topoisomerase II within a subdomain of the major human X alpha-satellite array

JM Spence, R Critcher, TA Ebersole, MM Valdivia, WC Earnshaw, T Fukagawa, CJ Farr

EMBO JOURNAL　Vol. 21　No. 19　p. 5269-5280　2002/10　Research paper (scientific journal)

Triplex-forming DNAs in the human interphase nucleus visualized in situ by polypurine/polypyrimidine DNA probes and antitriplex antibodies

M Ohno, T Fukagawa, JS Lee, T Ikemura

CHROMOSOMA　Vol. 111　No. 3　p. 201-213　2002/09　Research paper (scientific journal)

CENP-I is essential for centromere function in vertebrate cells

A Nishihashi, T Haraguchi, Y Hiraoka, T Ikemura, Regnier, V, H Dodson, WC Earnshaw, T Fukagawa

DEVELOPMENTAL CELL　Vol. 2　No. 4　p. 463-476　2002/04　Research paper (scientific journal)

Generation and phenotypic analysis of conditionally inactivated mutant cells

E Sonoda, T Fukagawa, A Kitao, S Takeda

GENOME SCIENCE: TOWARDS A NEW PARADIGM?　Vol. 1246　p. 55-74　2002　Research paper (international conference proceedings)

Scc1/Rad21/Mcd1 is required for sister chromatid cohesion and kinetochore function in vertebrate cells

E Sonoda, T Matsusaka, C Morrison, P Vagnarelli, O Hoshi, T Ushiki, K Nojima, T Fukagawa, IC Waizenegger, JM Peters, WC Earnshaw, S Takeda

DEVELOPMENTAL CELL　Vol. 1　No. 6　p. 759-770　2001/12　Research paper (scientific journal)

Creation and characterization of temperature-sensitive CENP-C mutants in vertebrate cells

T Fukagawa, Regnier, V, T Ikemura

NUCLEIC ACIDS RESEARCH　Vol. 29　No. 18　p. 3796-3803　2001/09　Research paper (scientific journal)

CENP-H, a constitutive centromere component, is required for centromere targeting of CENP-C in vertebrate cells

T Fukagawa, Y Mikami, A Nishihashi, Regnier, V, T Haraguchi, Y Hiraoka, N Sugata, K Todokoro, W Brown, T Ikemura

EMBO JOURNAL　Vol. 20　No. 16　p. 4603-4617　2001/08　Research paper (scientific journal)

Gene structure, chromosomal localization and immunolocalization of chicken centromere proteins CENP-C and ZW10

A Okamura, C Pendon, MM Valdivia, T Ikemura, T Fukagawa

GENE　Vol. 262　No. 1-2　p. 283-290　2001/01　Research paper (scientific journal)

Distribution of polypurine/polypyrimidine tract sequences in the human MHC region and their possible functions

S Kanaya, T Fukagawa, A Ando, H Inoko, Y Kudo, T Ikemura

MAJOR HISTOCOMPATIBILITY COMPLEX　p. 131-145　2000　Research paper (international conference proceedings)

CENP-C is necessary but not sufficient to induce formation of functional centromere

T Fukagawa, C Pendon, J Morris, W Brown

EMBO JOURNAL　Vol. 18　No. 15　p. 4196-4209　1999/08　Research paper (scientific journal)

The chicken HPRT gene: a counter selectable marker for the DT40 cell line

T Fukagawa, N Hayward, JA Yang, C Azzalin, D Griffin, AF Stewart, W Brown

NUCLEIC ACIDS RESEARCH　Vol. 27　No. 9　p. 1966-1969　1999/05　Research paper (scientific journal)

Efficient conditional mutation of the vertebrate CENP-C gene

T Fukagawa, WRA Brown

HUMAN MOLECULAR GENETICS　Vol. 6　No. 13　p. 2301-2308　1997/12　Research paper (scientific journal)

Precise switching of DNA replication timing in the GC content transition area in the human major histocompatibility complex

T Tenzen, T Yamagata, T Fukagawa, K Sugaya, A Ando, H Inoko, T Gojobori, A Fujiyama, K Okumura, T Ikemura

MOLECULAR AND CELLULAR BIOLOGY　Vol. 17　No. 7　p. 4043-4050　1997/07　Research paper (scientific journal)

Gene organization of human NOTCH4 and (CTG)(n) polymorphism in this human counterpart gene of mouse proto-oncogene Int3

K Sugaya, S Sasanuma, J Nohata, T Kimura, T Fukagawa, Y Nakamura, A Ando, H Inoko, T Ikemura, K Mita

GENE　Vol. 189　No. 2　p. 235-244　1997/04　Research paper (scientific journal)

[Biological significance of human chromosome bands].

Fukagawa T, Ohno M, Ikemura T

Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme　Vol. 41　No. 15 Suppl　p. 2277-2287　1996/11

Cloning, sequencing and evolutionary analyses of the human major histocompatibility complex (MHC) region

H. Inoko, N. Mizuki, T. Shiina, A. Ando, M. Kimura, Yy. Kikuchi, H. Kawata, K. Sugaya, T. Fukagawa, K. Matsumoto, T. Nagata, M. Taketo, K. Okumura, M. Kasahara, T. Ikemura

Mitochondrial DNA　Vol. 7　No. 1　p. 31-32　1996　Research paper (scientific journal)

Cloning, sequencing and evolutionary analyses of the human major histocompatibility complex (MHC) region

H Inoko, N MIzuki, T Shiina, A Ando, M Kimura, YY Kikuchi, H Kawata, K Sugaya, T Fukagawa, K Matsumoto, T Nagata, M Taketo, K Okumura, M Kasahara, T Ikemura

DNA SEQUENCE　Vol. 7　No. 1　p. 31-32　1996　Research paper (scientific journal)

Human pseudoautosomal boundary-like sequences: Expression and involvement in evolutionary formation of the present-day pseudoautosomal boundary of human sex chromosomes

T Fukagawa, Y Nakamura, K Okumura, M Nogami, A Ando, H Inoko, N Saitou, T Ikemura

HUMAN MOLECULAR GENETICS　Vol. 5　No. 1　p. 23-32　1996/01　Research paper (scientific journal)

TRIBUTYLTIN-RESISTANT MARINE-BACTERIA - A SUMMARY OF RECENT WORK

S SUZUKI, T FUKAGAWA

JOURNAL OF INDUSTRIAL MICROBIOLOGY　Vol. 14　No. 2　p. 154-158　1995/02　Research paper (scientific journal)

A BOUNDARY OF LONG-RANGE G+C-PERCENT MOSAIC DOMAINS IN THE HUMAN MHC LOCUS - PSEUDOAUTOSOMAL BOUNDARY-LIKE SEQUENCE EXISTS NEAR THE BOUNDARY

T FUKAGAWA, K SUGAYA, K MATSUMOTO, K OKUMURA, A ANDO, H INOKO, T IKEMURA

GENOMICS　Vol. 25　No. 1　p. 184-191　1995/01　Research paper (scientific journal)

[Evolution at levels of DNA and chromosomal bands].

Fukagawa T, Sugaya K, Nakamura Y, Ikemura T

Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme　Vol. 39　No. 15　p. 2490-2501　1994/11

3 GENES IN THE HUMAN MHC CLASS-III REGION NEAR THE JUNCTION WITH THE CLASS-II - GENE FOR RECEPTOR OF ADVANCED GLYCOSYLATION END-PRODUCTS, PBX2 HOMEOBOX GENE AND A NOTCH HOMOLOG, HUMAN COUNTERPART OF MOUSE MAMMARY-TUMOR GENE INT-3

K SUGAYA, T FUKAGAWA, K MATSUMOTO, K MITA, E TAKAHASHI, A ANDO, H INOKO, T IKEMURA

GENOMICS　Vol. 23　No. 2　p. 408-419　1994/09　Research paper (scientific journal)

Estimation of protein-production levels for ORFs found by E. coli and yeast genome projects, basing on levels of "optimal codon" usage, in connection with feasibility of their protein coding ability and with assignment to foreign-type genes

Nakamura Y., Fukagawa T., Sugaya K., Ikemura T.

GI　Vol. 5　p. 188-189　1994

THE 16S RIBOSOMAL-RNA SEQUENCE AND GENOME SIZING OF TRIBUTYLTIN RESISTANT MARINE BACTERIUM, STRAIN M-1

S SUZUKI, K KITATSUKAMOTO, T FUKAGAWA

MICROBIOS　Vol. 77　No. 311　p. 101-109　1994　Research paper (scientific journal)

CLONING OF GENE RESPONSIBLE FOR TRIBUTYLTIN CHLORIDE (TBTCL) RESISTANCE IN TBTCL-RESISTANT MARINE BACTERIUM, ALTEROMONAS SP M-1

T FUKAGAWA, S SUZUKI

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS　Vol. 194　No. 2　p. 733-740　1993/07　Research paper (scientific journal)

A sensitive and efficient homology search method to find proteincoding regions using "protein-coding region DNA database"

Wada K., Wada Y., Tanaka S., Doi H., Nakamura Y., Sugaya K., Fukagawa T., Ikemura T.

GI　Vol. 4　p. 347-351　1993

OCCURRENCE OF TRIBUTYLTIN-TOLERANT BACTERIA IN TRIBUTYLTIN-CONTAINING OR CADMIUM-CONTAINING SEAWATER

S SUZUKI, T FUKAGAWA, K TAKAMA

APPLIED AND ENVIRONMENTAL MICROBIOLOGY　Vol. 58　No. 10　p. 3410-3412　1992/10

ISOLATION AND CHARACTERIZATION OF TRIBUTYLTIN CHLORIDE-RESISTANT MARINE VIBRIO

T FUKAGAWA, S SUZUKI, K FUKUNAGA, T SUZUKI, K TAKAMA

FEMS MICROBIOLOGY LETTERS　Vol. 93　No. 1　p. 83-86　1992/05　Research paper (scientific journal)