Transcriptome signature in the blood of neuromyelitis optica spectrum disorder under steroid tapering.

Ryohei Yamamura, Makoto Kinoshita, Yoshiaki Yasumizu, Tomohiro Yata, Keigo Kihara, Daisuke Motooka, Naoyuki Shiraishi, Yasuko Sugiyama, Shohei Beppu, Hisashi Murata, Naoshi Koizumi, Itsuki Sano, Toru Koda, Tatsusada Okuno, Hideki Mochizuki

Frontiers in immunology　Vol. 16　p. 1508977-1508977　2025/02/03　Research paper (scientific journal)

Bacterial information in serum extracellular vesicles reflects the inflammation of adherent perinephric fat.

Toshihiro Uemura, Atsunari Kawashima, Kentaro Jingushi, Daisuke Motooka, Takuro Saito, Nesrine Sassi, Yuki Horibe, Akinaru Yamamoto, Yutong Liu, Masaru Tani, Akihiro Yoshimura, Toshiki Oka, Yohei Okuda, Gaku Yamamichi, Yu Ishizuya, Yoshiyuki Yamamoto, Taigo Kato, Koji Hatano, Kazutake Tsujikawa, Hisashi Wada, Norio Nonomura

Cancer science　Vol. 116　No. 2　p. 338-349　2025/02/01　Research paper (scientific journal)

Comparative analysis of gut microbiota in hormone-sensitive and castration-resistant prostate cancer in Japanese men.

Saizo Fujimoto, Koji Hatano, Eri Banno, Daisuke Motooka, Marco Antonio De Velasco, Yurie Kura, Shingo Toyoda, Mamoru Hashimoto, Shogo Adomi, Takafumi Minami, Kazuhiro Yoshimura, Toshiki Oka, Junya Hata, Makoto Matsushita, Tetsuya Takao, Shingo Takada, Akira Tsujimura, Yasuyuki Kojima, Wataru Obara, Shota Nakamura, Hirotsugu Uemura, Norio Nonomura, Kazutoshi Fujita

Cancer science　Vol. 116　No. 2　p. 462-469　2025/02/01　Research paper (scientific journal)

A comprehensive analysis of antimicrobial resistance of clinical emm89 Streptococcus pyogenes in Japan.

Weichen Gong, Masayuki Ono, Masaya Yamaguchi, Daisuke Motooka, Yujiro Hirose, Kotaro Higashi, Momoko Kobayashi, Eri Ikeda, Tomoko Sumitomo, Rumi Okuno, Takahiro Yamaguchi, Ryuji Kawahara, Hitoshi Otsuka, Noriko Nakanishi, Yu Kazawa, Chikara Nakagawa, Ryo Yamaguchi, Hiroo Sakai, Yuko Matsumoto, Tadayoshi Ikebe, Shigetada Kawabata

JAC-antimicrobial resistance　Vol. 7　No. 1　2025/02　Research paper (scientific journal)

Spatial transcriptome analysis of lung squamous cell carcinoma arising from interstitial pneumonia provides insights into tumor heterogeneity.

Koto Ukon, Satoshi Nojima, Daisuke Motooka, Tsuyoshi Takashima, Masaharu Kohara, Hiroki Kiyokawa, Kenji Kimura, Eriko Fukui, Shinichiro Tahara, Kansuke Kido, Takahiro Matsui, Yasushi Shintani, Daisuke Okuzaki, Eiichi Morii

Pathology, research and practice　Vol. 266　p. 155805-155805　2025/02/01　Research paper (scientific journal)

Full-length nanopore sequencing of circular RNA landscape in peripheral blood cells following sequential BNT162b2 mRNA vaccination.

Yu-Chen Liu, Masakazu Ishikawa, Shuhei Sakakibara, Mohamad Al Kadi, Daisuke Motooka, Yoko Naito, Shingo Ito, Yuko Imamura, Hisatake Matsumoto, Fuminori Sugihara, Haruhiko Hirata, Hiroshi Ogura, Daisuke Okuzaki

Gene　Vol. 933　p. 148971-148971　2025/01/15　Research paper (scientific journal)

Intrahepatic Exhausted Antiviral Immunity in an Immunocompetent Mouse Model of Chronic Hepatitis B.

Satoshi Shigeno, Takahiro Kodama, Kazuhiro Murai, Daisuke Motooka, Akihisa Fukushima, Akira Nishio, Hayato Hikita, Tomohide Tatsumi, Toru Okamoto, Tatsuya Kanto, Tetsuo Takehara

Cellular and molecular gastroenterology and hepatology　Vol. 19　No. 1　p. 101412-101412　2025/01/01　Research paper (scientific journal)

Identifying Genetic Variations in emm89 Streptococcus pyogenes Linked to Severe Invasive Infections

Masayuki Ono, Masaya Yamaguchi, Daisuke Motooka, Yujiro Hirose, Kotaro Higashi, Tomoko Sumitomo, Tohru Miyoshi-Akiyama, Rumi Okuno, Takahiro Yamaguchi, Ryuji Kawahara, Hitoshi Otsuka, Noriko Nakanishi, Yu Kazawa, Chikara Nakagawa, Ryo Yamaguchi, Hiroo Sakai, Yuko Matsumoto, Tadayoshi Ikebe, Shigetada Kawabata

eLife　Vol. 14　2025/01　Research paper (scientific journal)

Novel integrated multiomics analysis reveals a key role for integrin beta-like 1 in wound scarring.

Sang-Eun Kim, Ryota Noda, Yu-Chen Liu, Yukari Nakajima, Shoichiro Kameoka, Daisuke Motooka, Seiya Mizuno, Satoru Takahashi, Kento Takaya, Takehiko Murase, Kazuya Ikematsu, Katsiaryna Tratsiakova, Takahiro Motoyama, Masahiro Nakashima, Kazuo Kishi, Paul Martin, Shigeto Seno, Daisuke Okuzaki, Ryoichi Mori

EMBO reports　Vol. 26　No. 1　p. 122-152　2025/01/01　Research paper (scientific journal)

Dysbiosis of the human skin mycobiome in patients receiving systemic IL-23 inhibitors.

Yuta Koike, Sayaka Kuwatsuka, Daisuke Motooka, Hiroyuki Murota

Allergology international : official journal of the Japanese Society of Allergology　Vol. 74　No. 1　p. 72-77　2025/01　Research paper (scientific journal)

D-loop mutations in mitochondrial DNA are a risk factor for chemotherapy resistance in esophageal cancer.

Takashi Harino, Koji Tanaka, Daisuke Motooka, Yasunori Masuike, Tsuyoshi Takahashi, Kotaro Yamashita, Takuro Saito, Kazuyoshi Yamamoto, Tomoki Makino, Yukinori Kurokawa, Kiyokazu Nakajima, Hidetoshi Eguchi, Yuichiro Doki

Scientific reports　Vol. 14　No. 1　p. 31653-31653　2024/12/30　Research paper (scientific journal)

A conserved human CD4+ T cell subset recognizing the mycobacterial adjuvant trehalose monomycolate.

Yuki Sakai, Minori Asa, Mika Hirose, Wakana Kusuhara, Nagatoshi Fujiwara, Hiroto Tamashima, Takahiro Ikazaki, Shiori Oka, Kota Kuraba, Kentaro Tanaka, Takashi Yoshiyama, Masamichi Nagae, Yoshihiko Hoshino, Daisuke Motooka, Ildiko Van Rhijn, Xiuyuan Lu, Eri Ishikawa, D Branch Moody, Takayuki Kato, Shinsuke Inuki, Go Hirai, Sho Yamasaki

The Journal of clinical investigation　Vol. 135　No. 6　2024/12/24　Research paper (scientific journal)

Age-associated aberrations of the cumulus-oocyte interaction and in the zona pellucida structure reduce fertility in female mice.

Yu Ishikawa-Yamauchi, Chihiro Emori, Hideto Mori, Tsutomu Endo, Kiyonori Kobayashi, Yuji Watanabe, Hiroshi Sagara, Takeshi Nagata, Daisuke Motooka, Akinori Ninomiya, Manabu Ozawa, Masahito Ikawa

Communications biology　Vol. 7　No. 1　p. 1692-1692　2024/12/24　Research paper (scientific journal)

Tau Accumulation Induces Microglial State Alterations in Alzheimer's Disease Model Mice.

Kenichi Nagata, Shoko Hashimoto, Daisuke Joho, Ryo Fujioka, Yukio Matsuba, Misaki Sekiguchi, Naomi Mihira, Daisuke Motooka, Yu-Chen Liu, Daisuke Okuzaki, Masataka Kikuchi, Shigeo Murayama, Takaomi C Saido, Hiroshi Kiyama, Hiroki Sasaguri

eNeuro　Vol. 11　No. 12　p. ENEURO.0260-24.2024　2024/12/01　Research paper (scientific journal)

Clonal landscape of autoantibody-secreting plasmablasts in COVID-19 patients.

Shuhei Sakakibara, Yu-Chen Liu, Masakazu Ishikawa, Ryuya Edahiro, Yuya Shirai, Soichiro Haruna, Marwa Ali El Hussien, Zichang Xu, Songling Li, Yuta Yamaguchi, Teruaki Murakami, Takayoshi Morita, Yasuhiro Kato, Haruhiko Hirata, Yoshito Takeda, Fuminori Sugihara, Yoko Naito, Daisuke Motooka, Chao-Yuan Tsai, Chikako Ono, Yoshiharu Matsuura, James B Wing, Hisatake Matsumoto, Hiroshi Ogura, Masato Okada, Atsushi Kumanogoh, Yukinari Okada, Daron M Standley, Hitoshi Kikutani, Daisuke Okuzaki

Life science alliance　Vol. 7　No. 12　2024/12　Research paper (scientific journal)

Variability of macrolide-resistant profile in Mycobacterium avium complex pulmonary disease.

Kiyoharu Fukushima, Yuki Matsumoto, Yuko Abe, Kazuki Hashimoto, Daisuke Motooka, Seigo Kitada, Haruko Saito, Sho Komukai, Eriko Fukui, Takayuki Niitsu, Hiroshi Nabeshima, Yasuharu Nagahama, June Yamauchi, Tadayoshi Nitta, Takuro Nii, Takanori Matsuki, Kazuyuki Tsujino, Keisuke Miki, Yasushi Shintani, Atsushi Kumanogoh, Shizuo Akira, Shota Nakamura, Hiroshi Kida

Antimicrobial agents and chemotherapy　Vol. 68　No. 11　2024/11/06　Research paper (scientific journal)

Non-activating ITGB3 mutation in β3 cytoplasmic region causes macrothrombocytopenia with impaired αIIbβ3/RhoA pathway

Keiichi Nakata, Keigo Akuta, Takaya Endo, Midori Koike, Daisuke Motooka, Daisuke Okuzaki, Hisashi Kato, Yoshiaki Tomiyama, Naoki Hosen, Hirokazu Kashiwagi

Blood Vessels, Thrombosis & Hemostasis　2024/11　Research paper (scientific journal)

The pyruvate-GPR31 axis promotes transepithelial dendrite formation in human intestinal dendritic cells.

Eri Oguro-Igashira, Mari Murakami, Ryota Mori, Ryuichi Kuwahara, Takako Kihara, Masaharu Kohara, Makoto Fujiwara, Daisuke Motooka, Daisuke Okuzaki, Mitsuru Arase, Hironobu Toyota, Siyun Peng, Takayuki Ogino, Yasuji Kitabatake, Eiichi Morii, Seiichi Hirota, Hiroki Ikeuchi, Eiji Umemoto, Atsushi Kumanogoh, Kiyoshi Takeda

Proceedings of the National Academy of Sciences of the United States of America　Vol. 121　No. 44　2024/10/29　Research paper (scientific journal)

Neoself-antigens are the primary target for autoreactive T cells in human lupus.

Shunsuke Mori, Masako Kohyama, Yoshiaki Yasumizu, Asa Tada, Kaito Tanzawa, Tatsuya Shishido, Kazuki Kishida, Hui Jin, Masayuki Nishide, Shoji Kawada, Daisuke Motooka, Daisuke Okuzaki, Ryota Naito, Wataru Nakai, Teru Kanda, Takayuki Murata, Chikashi Terao, Koichiro Ohmura, Noriko Arase, Tomohiro Kurosaki, Manabu Fujimoto, Tadahiro Suenaga, Atsushi Kumanogoh, Shimon Sakaguchi, Yoshihiro Ogawa, Hisashi Arase

Cell　Vol. 187　No. 21　p. 6071-6087　2024/10/17　Research paper (scientific journal)

A plasmid-mediated type III secretion system associated with invasiveness and diarrheagenicity of Providencia rustigianii.

Jayedul Hassan, Atsushi Hinenoya, Noritoshi Hatanaka, Sharda Prasad Awasthi, Goutham Belagula Manjunath, Nahid Rahman, Jyoji Yamate, Shota Nakamura, Daisuke Motooka, Akira Nagita, Shah M Faruque, Shinji Yamasaki

mBio　Vol. 15　No. 10　2024/10/16　Research paper (scientific journal)

Cases of endophthalmitis caused by Candida albicans and Candida dubliniensis identified via internal transcribed spacer deep sequencing.

Kazunobu Asao, Noriyasu Hashida, Kazuichi Maruyama, Daisuke Motooka, Shota Nakamura, Kohji Nishida

BMC ophthalmology　Vol. 24　No. 1　p. 444-444　2024/10/09　Research paper (scientific journal)

Spatial transcriptomics elucidates medulla niche supporting germinal center response in myasthenia gravis-associated thymoma.

Yoshiaki Yasumizu, Makoto Kinoshita, Martin Jinye Zhang, Daisuke Motooka, Koichiro Suzuki, Satoshi Nojima, Naoshi Koizumi, Daisuke Okuzaki, Soichiro Funaki, Yasushi Shintani, Naganari Ohkura, Eiichi Morii, Tatsusada Okuno, Hideki Mochizuki

Cell reports　Vol. 43　No. 9　p. 114677-114677　2024/09/24　Research paper (scientific journal)

Gut Dysbiosis in Patients With Fontan Circulation.

Hideo Ohuchi, Ryotaro Asano, Aki Mori, Tomohiko Ishibashi, Daisuke Motooka, Michikazu Nakai, Yoshikazu Nakaoka

Journal of the American Heart Association　Vol. 13　No. 18　2024/09/17　Research paper (scientific journal)

Paraclostridium tenue Causing an Anaerobic Brain Abscess Identified by Whole-Metagenome Sequencing: A Case Report.

Tetsuya Chiba, Yorito Hattori, Daisuke Motooka, Tomotaka Tanaka, Masafumi Ihara

Microorganisms　Vol. 12　No. 8　2024/08/16　Research paper (scientific journal)

Identification of causative fungus from sterile abscess using metagenomics followed by in situ hybridization.

Hiroya Oki, Ryotaro Niwa, Somboonthum Pranee, Daisuke Motooka, Yoshiyuki Onda, Jun Nakata, Hiroko Nakajima, Yoshihiro Oka, Haruo Sugiyama, Yuka Yoshii, Naoyuki Anzai, Shota Nakamura, Tetsuya Iida

Access microbiology　Vol. 6　No. 8　2024/08　Research paper (scientific journal)

High N6-methyladenosine-activated TCEAL8 mRNA is a novel pancreatic cancer marker.

Tomoaki Hara, Sikun Meng, Hiromichi Sato, Shotaro Tatekawa, Kazuki Sasaki, Yu Takeda, Yoshiko Tsuji, Yasuko Arao, Ken Ofusa, Toru Kitagawa, Daisaku Yamada, Hidenori Takahashi, Shogo Kobayashi, Daisuke Motooka, Yutaka Suzuki, Sarah Rennie, Shizuka Uchida, Masaki Mori, Kazuhiko Ogawa, Yuichiro Doki, Hidetoshi Eguchi, Hideshi Ishii

Cancer science　Vol. 115　No. 7　p. 2360-2370　2024/07/01　Research paper (scientific journal)

Fat and proteolysis due to methionine, tryptophan, and niacin deficiency leads to alterations in gut microbiota and immune modulation in inflammatory bowel disease.

Tomoaki Hara, Sikun Meng, Daisuke Motooka, Hiromichi Sato, Yasuko Arao, Yoshiko Tsuji, Takeshi Yabumoto, Yuichiro Doki, Hidetoshi Eguchi, Shizuka Uchida, Hideshi Ishii

Cancer science　Vol. 115　No. 7　p. 2473-2485　2024/07/01　Research paper (scientific journal)

Significance of signal recognition particle 9 nuclear translocation: Implications for pancreatic cancer prognosis and functionality.

Hiromichi Sato, Sikun Meng, Kazuki Sasaki, Shogo Kobayashi, Kansuke Kido, Yoshiko Tsuji, Yasuko Arao, Yoshiko Saito, Yoshifumi Iwagami, Daisaku Yamada, Yoshito Tomimaru, Takehiro Noda, Hidenori Takahashi, Daisuke Motooka, Shizuka Uchida, Ken Ofusa, Taroh Satoh, Yuichiro Doki, Hidetoshi Eguchi, Tomoaki Hara, Hideshi Ishii

International journal of oncology　Vol. 65　No. 1　2024/07/01　Research paper (scientific journal)

Clonality Analysis of Streptococcus pneumoniae in Clinical Specimens

Delly Chipta Lestari, Pranee Somboonthum, Daisuke Motooka, Eiji Ishii, Shigeaki Matsuda, Anis Karuniawati, Tetsuya Iida

Microbiology Research　Vol. 15　No. 3　p. 1110-1118　2024/06/29　Research paper (scientific journal)

Deletion of the mRNA endonuclease Regnase-1 promotes NK cell anti-tumor activity via OCT2-dependent transcription of Ifng.

Xin Sun, Yasuharu Nagahama, Shailendra Kumar Singh, Yuuki Kozakai, Hiroshi Nabeshima, Kiyoharu Fukushima, Hiroki Tanaka, Daisuke Motooka, Eriko Fukui, Eric Vivier, Diego Diez, Shizuo Akira

Immunity　Vol. 57　No. 6　p. 1360-1377　2024/06/11　Research paper (scientific journal)

Far-East Asian Toxoplasma isolates share ancestry with North and South/Central American recombinant lineages.

Fumiaki Ihara, Hisako Kyan, Yasuhiro Takashima, Fumiko Ono, Kei Hayashi, Tomohide Matsuo, Makoto Igarashi, Yoshifumi Nishikawa, Kenji Hikosaka, Hirokazu Sakamoto, Shota Nakamura, Daisuke Motooka, Kiyoshi Yamauchi, Madoka Ichikawa-Seki, Shinya Fukumoto, Motoki Sasaki, Hiromi Ikadai, Kodai Kusakisako, Yuma Ohari, Ayako Yoshida, Miwa Sasai, Michael E Grigg, Masahiro Yamamoto

Nature communications　Vol. 15　No. 1　p. 4278-4278　2024/05/22　Research paper (scientific journal)

Turicibacter faecis sp. nov., isolated from faeces of heart failure mouse model.

Yuko Imamura, Daisuke Motooka, Yuri Nakajima, Shin Ito, Masafumi Kitakaze, Tetsuya Iida, Shota Nakamura

International journal of systematic and evolutionary microbiology　Vol. 74　No. 5　2024/05/01　Research paper (scientific journal)

Periportal macrophages protect against commensal-driven liver inflammation.

Yu Miyamoto, Junichi Kikuta, Takahiro Matsui, Tetsuo Hasegawa, Kentaro Fujii, Daisuke Okuzaki, Yu-Chen Liu, Takuya Yoshioka, Shigeto Seno, Daisuke Motooka, Yutaka Uchida, Erika Yamashita, Shogo Kobayashi, Hidetoshi Eguchi, Eiichi Morii, Karl Tryggvason, Takashi Shichita, Hisako Kayama, Koji Atarashi, Jun Kunisawa, Kenya Honda, Kiyoshi Takeda, Masaru Ishii

Nature　Vol. 629　No. 8013　p. 901-909　2024/05/01　Research paper (scientific journal)

Regulation of muscle hypertrophy through granulin: Relayed communication among mesenchymal progenitors, macrophages, and satellite cells.

Lidan Zhang, Hayato Saito, Tatsuyoshi Higashimoto, Takayuki Kaji, Ayasa Nakamura, Kanako Iwamori, Ryoko Nagano, Daisuke Motooka, Daisuke Okuzaki, Akiyoshi Uezumi, Shigeto Seno, So-Ichiro Fukada

Cell reports　Vol. 43　No. 4　p. 114052-114052　2024/04/23　Research paper (scientific journal)

Squamous cell carcinoma initially occurring on the tongue dorsum: a case series report with molecular analysis.

Sawako Ono, Katsutoshi Hirose, Shintaro Sukegawa, Kyoichi Obata, Masanori Masui, Kazuaki Hasegawa, Ai Fujimura, Katsumitsu Shimada, Satoko Nakamura, Akari Teramoto, Yumiko Hori, Eiichi Morii, Daisuke Motooka, Takuro Igawa, Takehiro Tanaka, Hitoshi Nagatsuka, Satoru Toyosawa, Hidetaka Yamamoto

Diagnostic pathology　Vol. 19　No. 1　p. 63-63　2024/04/22　Research paper (scientific journal)

Vero cell-adapted SARS-CoV-2 strain shows increased viral growth through furin-mediated efficient spike cleavage.

Shohei Minami, Tomohiro Kotaki, Yusuke Sakai, Shinya Okamura, Shiho Torii, Chikako Ono, Daisuke Motooka, Rina Hamajima, Ryotaro Nouda, Jeffery A Nurdin, Moeko Yamasaki, Yuta Kanai, Hirotaka Ebina, Yusuke Maeda, Toru Okamoto, Taro Tachibana, Yoshiharu Matsuura, Takeshi Kobayashi

Microbiology spectrum　Vol. 12　No. 4　2024/04/02　Research paper (scientific journal)

Clostridium butyricum Bacteremia Associated with Probiotic Use, Japan.

Ryuichi Minoda Sada, Hiroo Matsuo, Daisuke Motooka, Satoshi Kutsuna, Shigeto Hamaguchi, Go Yamamoto, Akiko Ueda

Emerging infectious diseases　Vol. 30　No. 4　p. 665-671　2024/04/01　Research paper (scientific journal)

RN7SL1 may be translated under oncogenic conditions.

Tomoaki Hara, Sikun Meng, Yoshiko Tsuji, Yasuko Arao, Yoshiko Saito, Hiromichi Sato, Daisuke Motooka, Shizuka Uchida, Hideshi Ishii

Proceedings of the National Academy of Sciences of the United States of America　Vol. 121　No. 12　2024/03/19　Research paper (scientific journal)

A genome-wide association study of emm89 Streptococcus pyogenes identifies genetic variations contributing to severe invasive infections

Masayuki Ono, Masaya Yamaguchi, Daisuke Motooka, Yujiro Hirose, Kotaro Higashi, Tomoko Sumitomo, Tohru Miyoshi-Akiyama, Rumi Okuno, Takahiro Yamaguchi, Ryuji Kawahara, Hitoshi Otsuka, Noriko Nakanishi, Yu Kazawa, Chikara Nakagawa, Ryo Yamaguchi, Hiroo Sakai, Yuko Matsumoto, Tadayoshi Ikebe, Shigetada Kawabata

2024/03/18

IncA/C plasmid encoding blaCTX-M-55 in non-O1 Vibrio cholerae isolates from the edible river fish Mastacembelus sp.

Takahiro Yamaguchi, Michio Jinnai, Doan Tran Nguyen Minh, Oanh Nguyen Hoang, Hien Le Thi, Phong Ngo Thanh, Phuong Hoang Hoai, Phuc Nguyen Do, Chinh Dang Van, Daisuke Motooka, Shota Nakamura, Yuko Kumeda, Atsushi Hase, Tatsuya Nakayama

Microbiology resource announcements　Vol. 13　No. 3　2024/03/12　Research paper (scientific journal)

Downregulation of TCF7 and LEF1 is a key determinant of tumor-infiltrating regulatory T-cell function.

Yujiro Kidani, Yohko Kitagawa, Masaki Hagiwara, Atsunari Kawashima, Takayuki Kanazawa, Hisashi Wada, Motohide Uemura, Norio Nonomura, Daisuke Motooka, Shota Nakamura, Naganari Ohkura, Shimon Sakaguchi

International immunology　Vol. 36　No. 4　p. 167-182　2024/03/09　Research paper (scientific journal)

The UDP-glucose/P2Y14 receptor axis promotes eosinophil-dependent large intestinal inflammation.

Li Liu, Takayoshi Ito, Bo Li, Haruka Tani, Daisuke Okuzaki, Daisuke Motooka, Hazuki Miyazaki, Takayuki Ogino, Shota Nakamura, Kiyoshi Takeda, Hisako Kayama

International immunology　Vol. 36　No. 4　p. 155-166　2024/03/09　Research paper (scientific journal)

肺非結核性抗酸菌症 肺Mycobacterium avium complex症におけるマクロライド耐性化の可塑性

安部 祐子, 福島 清春, 松本 悠希, 北田 清悟, 元岡 大祐, 新津 敬之, 新居 卓朗, 松本 隆典, 熊ノ郷 淳, 中村 昇太, 木田 博

日本呼吸器学会誌　Vol. 13　No. 増刊　p. 188-188　2024/03

ゲノム解析が紐解くMycobacterium gordonae症の多様性

安部 祐子, 福島 清春, 松本 悠希, 松木 隆典, 元岡 大祐, 新津 敬之, 辻野 和之, 三木 啓資, 熊ノ郷 淳, 中村 昇太, 木田 博

日本呼吸器学会誌　Vol. 13　No. 増刊　p. 324-324　2024/03

リアルタイムコアゲノム解析による非結核性抗酸菌症の迅速・高精度同定法の確立および臨床応用

新居 卓朗, 福島 清春, 松本 悠希, 松木 隆典, 元岡 大祐, 辻野 和之, 三木 啓資, 熊ノ郷 淳, 中村 昇太, 木田 博

日本呼吸器学会誌　Vol. 13　No. 増刊　p. 324-324　2024/03

Genome-wide loss-of-function genetic screen identifies INSIG2 as the vulnerability of hepatitis B virus-integrated hepatoma cells.

Makoto Fukuoka, Takahiro Kodama, Kazuhiro Murai, Hayato Hikita, Emi Sometani, Jihyun Sung, Akiyoshi Shimoda, Satoshi Shigeno, Daisuke Motooka, Akira Nishio, Kunimaro Furuta, Tomohide Tatsumi, Kosuke Yusa, Tetsuo Takehara

Cancer science　Vol. 115　No. 3　p. 859-870　2024/03/01　Research paper (scientific journal)

Comprehensive phenotypic and genomic characterization of venous malformations.

Katsutoshi Hirose, Yumiko Hori, Michio Ozeki, Daisuke Motooka, Kenji Hata, Shinichiro Tahara, Takahiro Matsui, Masaharu Kohara, Kazuaki Maruyama, Kyoko Imanaka-Yoshida, Satoru Toyosawa, Eiichi Morii

Human pathology　Vol. 145　p. 48-55　2024/03/01　Research paper (scientific journal)

Single-cell transcriptome landscape of circulating CD4+ T cell populations in autoimmune diseases.

Yoshiaki Yasumizu, Daiki Takeuchi, Reo Morimoto, Yusuke Takeshima, Tatsusada Okuno, Makoto Kinoshita, Takayoshi Morita, Yasuhiro Kato, Min Wang, Daisuke Motooka, Daisuke Okuzaki, Yamami Nakamura, Norihisa Mikami, Masaya Arai, Xuan Zhang, Atsushi Kumanogoh, Hideki Mochizuki, Naganari Ohkura, Shimon Sakaguchi

Cell genomics　Vol. 4　No. 2　p. 100473-100473　2024/02/14　Research paper (scientific journal)

Multiple ageing effects on testicular/epididymal germ cells lead to decreased male fertility in mice.

Tsutomu Endo, Kiyonori Kobayashi, Takafumi Matsumura, Chihiro Emori, Manabu Ozawa, Shimpei Kawamoto, Daisuke Okuzaki, Keisuke Shimada, Haruhiko Miyata, Kentaro Shimada, Mayo Kodani, Yu Ishikawa-Yamauchi, Daisuke Motooka, Eiji Hara, Masahito Ikawa

Communications biology　Vol. 7　No. 1　p. 16-16　2024/01/04　Research paper (scientific journal)

Dysbiosis of gut microbiota in patients with severe COVID-19.

Kentaro Shimizu, Haruhiko Hirata, Natsuko Tokuhira, Daisuke Motooka, Shota Nakamura, Akiko Ueda, Jotaro Tachino, Moe Koide, Akinori Uchiyama, Hiroshi Ogura, Jun Oda

Acute medicine & surgery　Vol. 11　No. 1　2024/01/01　Research paper (scientific journal)

Detection of chromosome-mediated blaNDM-1-carrying Aeromonas spp. in the intestinal contents of fresh water river fish in Ho Chi Minh City, Vietnam.

Takahiro Yamaguchi, Masaharu Yokota, Michio Jinnai, Doan Tran Nguyen Minh, Oanh Nguyen Hoang, Hien Le Thi, Phong Ngo Thanh, Phuong Hoang Hoai, Phuc Nguyen Do, Chinh Dang Van, Daisuke Motooka, Shota Nakamura, Ryuji Kawahara, Yuko Kumeda, Atsushi Hase, Tatsuya Nakayama

Marine pollution bulletin　Vol. 198　p. 115812-115812　2024/01/01　Research paper (scientific journal)

Identification of invasive subpopulations using spatial transcriptome analysis in thyroid follicular tumors.

Ayana Suzuki, Satoshi Nojima, Shinichiro Tahara, Daisuke Motooka, Masaharu Kohara, Daisuke Okuzaki, Mitsuyoshi Hirokawa, Eiichi Morii

Journal of pathology and translational medicine　Vol. 58　No. 1　p. 22-28　2024/01/01　Research paper (scientific journal)

Age-related decline in spermatogenic activity accompanied with endothelial cell senescence in male mice.

Manabu Ozawa, Hideto Mori, Tsutomu Endo, Yu Ishikawa-Yamauchi, Daisuke Motooka, Chihiro Emori, Masahiro Ikawa

iScience　Vol. 26　No. 12　p. 108456-108456　2023/12/15　Research paper (scientific journal)

Omics-Based Mathematical Modeling Unveils Pathogenesis of Periodontitis in an Experimental Murine Model

C. Fujihara, K. Murakami, S. Magi, D. Motooka, T. Nantakeeratipat, A. Canela, R. J. Tanaka, M. Okada, S. Murakami

Journal of Dental Research　Vol. 102　No. 13　p. 1468-1477　2023/12/01　Research paper (scientific journal)

The Rax homeoprotein in Müller glial cells is required for homeostasis maintenance of the postnatal mouse retina.

Takuya Yoshimoto, Taro Chaya, Leah R Varner, Makoto Ando, Toshinori Tsujii, Daisuke Motooka, Kazuhiro Kimura, Takahisa Furukawa

The Journal of biological chemistry　Vol. 299　No. 12　p. 105461-105461　2023/12/01　Research paper (scientific journal)

Single-cell analysis for identification of T-cell clonotypes associated with IgG4 production of autoimmune pancreatitis.

Kensuke Shibata, Nao Fujimori, Takamasa Oono, Daisuke Motooka, Daisuke Okuzaki, Koh-Hei Sonoda, Yoshihiro Ogawa, Sho Yamasaki

Gastroenterology report　Vol. 11　2023/12　Research paper (scientific journal)

Clear Cell Squamous Cell Carcinoma of the Maxillary Gingiva Associated with PIK3CA and HRAS Mutations: Report of a Case and Literature Review.

Katsutoshi Hirose, Takumi Shibahara, Akari Teramoto, Yu Usami, Sawako Ono, Yuri Iwamoto, Shumei Murakami, Kaori Oya, Narikazu Uzawa, Daisuke Motooka, Yumiko Hori, Eiichi Morii, Satoru Toyosawa

Head and neck pathology　Vol. 17　No. 4　p. 1026-1033　2023/12　Research paper (scientific journal)

Adult-onset botulism in a Japanese woman with prolonged spore excretion.

Keigo Kihara, Yuta Kajiyama, Yasuyoshi Kimura, Shuhei Okazaki, Naoya Esa, Ryosuke Nobe, Kentaro Shimizu, Kiyoshi Ohno, Daisuke Motooka, Takuhiro Matsumura, Takeshi Shimazu, Shota Nakamura, Yukako Fujinaga, Hideki Mochizuki

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy　Vol. 29　No. 12　p. 1172-1176　2023/12　Research paper (scientific journal)

Analysis of gut microbiome, host genetics, and plasma metabolites reveals gut microbiome-host interactions in the Japanese population.

Yoshihiko Tomofuji, Toshihiro Kishikawa, Kyuto Sonehara, Yuichi Maeda, Kotaro Ogawa, Shuhei Kawabata, Eri Oguro-Igashira, Tatsusada Okuno, Takuro Nii, Makoto Kinoshita, Masatoshi Takagaki, Kenichi Yamamoto, Noriko Arase, Mayu Yagita-Sakamaki, Akiko Hosokawa, Daisuke Motooka, Yuki Matsumoto, Hidetoshi Matsuoka, Maiko Yoshimura, Shiro Ohshima, Shota Nakamura, Manabu Fujimoto, Hidenori Inohara, Haruhiko Kishima, Hideki Mochizuki, Kiyoshi Takeda, Atsushi Kumanogoh, Yukinori Okada

Cell reports　Vol. 42　No. 11　p. 113324-113324　2023/11/28　Research paper (scientific journal)

高齢で発症し,完全閉じ込め症候群を呈したボツリヌス症の一例

木原 圭梧, 梶山 裕太, 木村 康義, 岡崎 周平, 望月 秀樹, 江左 尚哉, 野邊 亮丞, 清水 健太郎, 嶋津 岳士, 大野 喜代志, 元岡 大祐, 中村 昇太, 松村 拓大, 藤永 由佳子, 余野木 伸哉, 河合 高生, 加藤 弘子, 永井 仁美, 谷掛 千里, 妹尾 充敏, 加藤 はる

病原微生物検出情報月報　Vol. 44　No. 11　p. 184-185　2023/11

An AsCas12f-based compact genome-editing tool derived by deep mutational scanning and structural analysis.

Tomohiro Hino, Satoshi N Omura, Ryoya Nakagawa, Tomoki Togashi, Satoru N Takeda, Takafumi Hiramoto, Satoshi Tasaka, Hisato Hirano, Takeshi Tokuyama, Hideki Uosaki, Soh Ishiguro, Madina Kagieva, Hiroyuki Yamano, Yuki Ozaki, Daisuke Motooka, Hideto Mori, Yuhei Kirita, Yoshiaki Kise, Yuzuru Itoh, Satoaki Matoba, Hiroyuki Aburatani, Nozomu Yachie, Tautvydas Karvelis, Virginijus Siksnys, Tsukasa Ohmori, Atsushi Hoshino, Osamu Nureki

Cell　Vol. 186　No. 22　p. 4920-4935　2023/10/26　Research paper (scientific journal)

Sialylation shapes mucus architecture inhibiting bacterial invasion in the colon.

Mugen Taniguchi, Ryu Okumura, Takahisa Matsuzaki, Ayaka Nakatani, Kei Sakaki, Shota Okamoto, Airi Ishibashi, Haruka Tani, Momoka Horikiri, Naritaka Kobayashi, Hiroshi Y Yoshikawa, Daisuke Motooka, Daisuke Okuzaki, Shota Nakamura, Toshiyuki Kida, Akihiko Kameyama, Kiyoshi Takeda

Mucosal immunology　Vol. 16　No. 5　p. 624-641　2023/10/01　Research paper (scientific journal)

Fungal dysbiosis and decreased tear mucin at the conjunctiva in patients with conjunctival mucosa-associated lymphoid tissue lymphoma.

Kazunobu Asao, Noriyasu Hashida, Daisuke Motooka, Teruhisa Tsukamoto, Shota Nakamura, Kazuichi Maruyama, Kohji Nishida

BMJ open ophthalmology　Vol. 8　No. 1　p. e001360-e001360　2023/09/30　Research paper (scientific journal)

Alteration of microbial composition in the skin and blood in vasculitis.

Ryujin Miyata, Chie Miyabe, Hiroya Oki, Daisuke Motooka, Shota Nakamura, Yoshishige Miyabe, Yuko Takenaka, Yasuko Fukuya, Kazuo Yudo, Naoko Ishiguro

Scientific reports　Vol. 13　No. 1　p. 15317-15317　2023/09/15　Research paper (scientific journal)

A cell wall synthase accelerates plasma membrane partitioning in mycobacteria.

Takehiro Kado, Zarina Akbary, Daisuke Motooka, Ian L Sparks, Emily S Melzer, Shota Nakamura, Enrique R Rojas, Yasu S Morita, M Sloan Siegrist

eLife　Vol. 12　2023/09/04　Research paper (scientific journal)

Bacteria-derived DNA in serum extracellular vesicles are biomarkers for renal cell carcinoma.

Toshihiro Uemura, Atsunari Kawashima, Kentaro Jingushi, Daisuke Motooka, Takuro Saito, Sassi Nesrine, Toshiki Oka, Yohei Okuda, Akinaru Yamamoto, Gaku Yamamichi, Eisuke Tomiyama, Yu Ishizuya, Yoshiyuki Yamamoto, Taigo Kato, Koji Hatano, Kazutake Tsujikawa, Hisashi Wada, Norio Nonomura

Heliyon　Vol. 9　No. 9　2023/09/01　Research paper (scientific journal)

Comparative evaluation of 16S rRNA metagenomic sequencing in the diagnosis and understanding of bacterial endophthalmitis.

Kazunobu Asao, Noriyasu Hashida, Kazuichi Maruyama, Daisuke Motooka, Teruhisa Tsukamoto, Yoshihiko Usui, Shota Nakamura, Kohji Nishida

BMJ open ophthalmology　Vol. 8　No. 1　2023/09/01　Research paper (scientific journal)

Genetic Landscape of Masticatory Muscle Tendon-Aponeurosis Hyperplasia.

Rina Tajima, Atsuko Okazaki, Tsuyoshi Sato, Kokoro Ozaki, Daisuke Motooka, Yasushi Okazaki, Tetsuya Yoda

Genes　Vol. 14　No. 9　p. 1718-1718　2023/08/29　Research paper (scientific journal)

Single-cell transcriptomics of human cholesteatoma identifies an activin A-producing osteoclastogenic fibroblast subset inducing bone destruction.

Kotaro Shimizu, Junichi Kikuta, Yumi Ohta, Yutaka Uchida, Yu Miyamoto, Akito Morimoto, Shinya Yari, Takashi Sato, Takefumi Kamakura, Kazuo Oshima, Ryusuke Imai, Yu-Chen Liu, Daisuke Okuzaki, Tetsuya Hara, Daisuke Motooka, Noriaki Emoto, Hidenori Inohara, Masaru Ishii

Nature communications　Vol. 14　No. 1　p. 4417-4417　2023/08/03　Research paper (scientific journal)

高脂肪食によるディスバイオシスが前立腺癌に及ぼす影響の解明

松下 慎, 藤田 和利, 林 拓自, 香山 尚子, 元岡 大祐, 長谷 拓明, 山本 顕生, 植村 俊彦, 山道 岳, 冨山 栄輔, 洪 陽子, 加藤 大悟, 波多野 浩士, 河嶋 厚成, 植村 元秀, 野島 聡, 今村 亮一, 辻川 和丈, 中村 昇太, 竹田 潔, 森井 英一, 野々村 祝夫

泌尿器外科　Vol. 36　No. 8　p. 895-896　2023/08

A cancer-associated METTL14 mutation induces aberrant m6A modification, affecting tumor growth.

Kotaro Miyake, Pedro Henrique Costa Cruz, Izumi Nagatomo, Yuki Kato, Daisuke Motooka, Shingo Satoh, Yuichi Adachi, Yoshito Takeda, Yukio Kawahara, Atsushi Kumanogoh

Cell reports　Vol. 42　No. 7　p. 112688-112688　2023/07/25　Research paper (scientific journal)

Zfp296 knockout enhances chromatin accessibility and induces a unique state of pluripotency in embryonic stem cells.

Satsuki Miyazaki, Hiroyuki Yamano, Daisuke Motooka, Fumi Tashiro, Takumi Matsuura, Tatsushi Miyazaki, Jun-Ichi Miyazaki

Communications biology　Vol. 6　No. 1　p. 771-771　2023/07/24　Research paper (scientific journal)

Wnt5a-YAP signaling axis mediates mechanotransduction in cardiac myocytes and contributes to contractile dysfunction induced by pressure overload.

Hiroshi Kishimoto, Masayoshi Iwasaki, Kensaku Wada, Keita Horitani, Osamu Tsukamoto, Kenta Kamikubo, Seitaro Nomura, Shinji Matsumoto, Takeshi Harada, Daisuke Motooka, Daisuke Okuzaki, Seiji Takashima, Issei Komuro, Akira Kikuchi, Ichiro Shiojima

iScience　Vol. 26　No. 7　p. 107146-107146　2023/07/21　Research paper (scientific journal)

Carbapenem triggers dissemination of chromosomally integrated carbapenemase genes via conjugative plasmids in Escherichia coli.

Ryuichiro Abe, Yukihiro Akeda, Yo Sugawara, Yuki Matsumoto, Daisuke Motooka, Tetsuya Iida, Shigeyuki Hamada

mSystems　Vol. 8　No. 3　2023/06/29　Research paper (scientific journal)

Temporal shifts in the predominant carbapenemase gene types among carbapenemase-producing Klebsiella pneumoniae isolated in Bangkok, Thailand, during 2013-2016.

Noriko Sakamoto, Warawut Laolerd, Yukihiro Akeda, Yo Sugawara, Daisuke Motooka, Norihisa Yamamoto, Dan Takeuchi, Rathina Kumar Shanmugakani, Isao Nishi, Masato Suzuki, Keigo Shibayama, Tetsuya Iida, Pitak Santanirand, Kazunori Tomono, Shigeyuki Hamada

Journal of medical microbiology　Vol. 72　No. 6　2023/06/09　Research paper (scientific journal)

MGIT-seqによる非結核性抗酸菌における菌株と薬剤耐性の同定

新津 敬之, 福島 清春, 松本 悠希, 松木 隆則, 齋藤 晴子, 元岡 大祐, 小向 翔, 福井 絵理子, 山内 寿里, 新田 忠義, 安部 祐子, 鍋島 弘嗣, 永濱 康晴, 新居 卓郎, 辻野 和之, 三木 啓資, 北田 清悟, 熊ノ郷 淳, 審良 静男, 中村 昇太, 木田 博

結核　Vol. 98　No. 4　p. 140-140　2023/06

マクロライド耐性肺Mycobacterium avium complex症における耐性化の可塑性と治療選択

安部 祐子, 福島 清春, 松本 悠希, 北田 清悟, 元岡 大祐, 新津 敬之, 新居 卓郎, 松木 隆則, 熊ノ郷 淳, 中村 昇太, 木田 博

結核　Vol. 98　No. 4　p. 143-143　2023/06

Reconstruction of the personal information from human genome reads in gut metagenome sequencing data.

Yoshihiko Tomofuji, Kyuto Sonehara, Toshihiro Kishikawa, Yuichi Maeda, Kotaro Ogawa, Shuhei Kawabata, Takuro Nii, Tatsusada Okuno, Eri Oguro-Igashira, Makoto Kinoshita, Masatoshi Takagaki, Kenichi Yamamoto, Takashi Kurakawa, Mayu Yagita-Sakamaki, Akiko Hosokawa, Daisuke Motooka, Yuki Matsumoto, Hidetoshi Matsuoka, Maiko Yoshimura, Shiro Ohshima, Shota Nakamura, Hidenori Inohara, Haruhiko Kishima, Hideki Mochizuki, Kiyoshi Takeda, Atsushi Kumanogoh, Yukinori Okada

Nature microbiology　Vol. 8　No. 6　p. 1079-1094　2023/06　Research paper (scientific journal)

COVID-19 relapse associated with SARS-CoV-2 evasion from CD4+ T-cell recognition in an agammaglobulinemia patient.

Ryo Morita, Ritsuko Kubota-Koketsu, Xiuyuan Lu, Tadahiro Sasaki, Emi E Nakayama, Yu-Chen Liu, Daisuke Okuzaki, Daisuke Motooka, James Badger Wing, Yasunori Fujikawa, Yuji Ichida, Kiyoko Amo, Tetsushi Goto, Junichi Hara, Michinori Shirano, Sho Yamasaki, Tatsuo Shioda

iScience　Vol. 26　No. 5　p. 106685-106685　2023/05/19　Research paper (scientific journal)

Food additive succinate exacerbates experimental autoimmune encephalomyelitis accompanied by increased IL-1β production.

Yasuko Sugiyama, Kazushiro Takata, Makoto Kinoshita, Daisuke Motooka, Naoyuki Shiraishi, Keigo Kihara, Hisashi Murata, Shohei Beppu, Toru Koda, Kazuya Yamashita, Akiko Namba, Kosuke Fujimoto, Atsushi Kumanogoh, Tatsusada Okuno, Hideki Mochizuki

Biochemical and biophysical research communications　Vol. 656　p. 97-103　2023/05/14　Research paper (scientific journal)

Genetic and phenotypic analyses of mcr-harboring extended-spectrum β-lactamase-producing Escherichia coli isolates from companion dogs and cats in Japan.

Mayo Yasugi, Shingo Hatoya, Daisuke Motooka, Daisuke Kondo, Hideo Akiyoshi, Masayuki Horie, Shota Nakamura, Terumasa Shimada

Veterinary microbiology　Vol. 280　p. 109695-109695　2023/05/01　Research paper (scientific journal)

Single-cell analyses and host genetics highlight the role of innate immune cells in COVID-19 severity.

Ryuya Edahiro, Yuya Shirai, Yusuke Takeshima, Shuhei Sakakibara, Yuta Yamaguchi, Teruaki Murakami, Takayoshi Morita, Yasuhiro Kato, Yu-Chen Liu, Daisuke Motooka, Yoko Naito, Ayako Takuwa, Fuminori Sugihara, Kentaro Tanaka, James B Wing, Kyuto Sonehara, Yoshihiko Tomofuji, Ho Namkoong, Hiromu Tanaka, Ho Lee, Koichi Fukunaga, Haruhiko Hirata, Yoshito Takeda, Daisuke Okuzaki, Atsushi Kumanogoh, Yukinori Okada

Nature genetics　Vol. 55　No. 5　p. 753-767　2023/05/01　Research paper (scientific journal)

Cancer-specific tissue-resident memory T-cells express ZNF683 in colorectal cancer.

Masatoshi Kitakaze, Mamoru Uemura, Tomoaki Hara, Ryota Chijimatsu, Daisuke Motooka, Toshiro Hirai, Masamitsu Konno, Daisuke Okuzaki, Yuki Sekido, Tsuyoshi Hata, Takayuki Ogino, Hidekazu Takahashi, Norikatsu Miyoshi, Ken Ofusa, Tsunekazu Mizushima, Hidetoshi Eguchi, Yuichiro Doki, Hideshi Ishii

British journal of cancer　Vol. 128　No. 10　p. 1828-1837　2023/05　Research paper (scientific journal)

Ovarian high-grade serous carcinoma cells with low SMARCA4 expression and high SMARCA2 expression contribute to platinum resistance.

Kansuke Kido, Satoshi Nojima, Daisuke Motooka, Yusuke Nomura, Masaharu Kohara, Kazuaki Sato, Kenji Ohshima, Shinichiro Tahara, Masako Kurashige, Daisuke Umeda, Tsuyoshi Takashima, Hiroki Kiyokawa, Koto Ukon, Takahiro Matsui, Daisuke Okuzaki, Eiichi Morii

The Journal of pathology　Vol. 260　No. 1　p. 56-70　2023/05　Research paper (scientific journal)

Tuberculostearic Acid Controls Mycobacterial Membrane Compartmentalization.

Malavika Prithviraj, Takehiro Kado, Jacob A Mayfield, David C Young, Annie D Huang, Daisuke Motooka, Shota Nakamura, M Sloan Siegrist, D Branch Moody, Yasu S Morita

mBio　Vol. 14　No. 2　2023/04/25　Research paper (scientific journal)

MGIT-seq for the Identification of Nontuberculous Mycobacteria and Drug Resistance: a Prospective Study.

Kiyoharu Fukushima, Yuki Matsumoto, Takanori Matsuki, Haruko Saito, Daisuke Motooka, Sho Komukai, Eriko Fukui, June Yamuchi, Tadayoshi Nitta, Takayuki Niitsu, Yuko Abe, Hiroshi Nabeshima, Yasuharu Nagahama, Takuro Nii, Kazuyuki Tsujino, Keisuke Miki, Seigo Kitada, Atsushi Kumanogoh, Shizuo Akira, Shota Nakamura, Hiroshi Kida

Journal of clinical microbiology　Vol. 61　No. 4　2023/04/20　Research paper (scientific journal)

Seasonal variations in gut microbiota and disease course in patients with inflammatory bowel disease.

Mizuki Tani, Shinichiro Shinzaki, Akiko Asakura, Taku Tashiro, Takahiro Amano, Yuriko Otake-Kasamoto, Takeo Yoshihara, Shunsuke Yoshii, Yoshiki Tsujii, Yoshito Hayashi, Takahiro Inoue, Daisuke Motooka, Shota Nakamura, Hideki Iijima, Tetsuo Takehara

PloS one　Vol. 18　No. 4　2023/04/18　Research paper (scientific journal)

Impact of G29179T mutation on two commercial PCR assays for SARS-CoV-2 detection

Wakaki Kami, Takeshi Kinjo, Hiroe Hashioka, Wakako Arakaki, Kohei Uechi, Ami Takahashi, Hiroya Oki, Kentaro Tanaka, Daisuke Motooka, Shota Nakamura, Masashi Nakamatsu, Shiro Maeda, Kazuko Yamamoto, Jiro Fujita

Journal of Virological Methods　Vol. 314　2023/04/01　Research paper (scientific journal)

Gut dysbiosis is associated with aortic aneurysm formation and progression in Takayasu arteritis.

Yusuke Manabe, Tomohiko Ishibashi, Ryotaro Asano, Shuichi Tonomura, Yuichi Maeda, Daisuke Motooka, Jin Ueda, Masahiro Yanagawa, Yuko Edamoto-Taira, Tomomi Chikaishi-Kirino, Takeshi Masaki, Tadakatsu Inagaki, Shota Nakamura, Yoshinori Katada, Makoto Okazawa, Masashi Narazaki, Takeshi Ogo, Atsushi Kumanogoh, Yoshikazu Nakaoka

Arthritis research & therapy　Vol. 25　No. 1　p. 46-46　2023/03/24　Research paper (scientific journal)

The kinetics of signaling through the common FcRγ chain determine cytokine profiles in dendritic cells.

Miyuki Watanabe, Daisuke Motooka, Sho Yamasaki

Science signaling　Vol. 16　No. 775　2023/03/07　Research paper (scientific journal)

肺NTM症 治療 マクロライド耐性肺Mycobacterium avium complex法における耐性化の可塑性と治療選択

安部 祐子, 福島 清春, 松本 悠希, 北田 清悟, 元岡 大祐, 新津 敬之, 新居 卓朗, 松木 隆典, 熊ノ郷 淳, 中村 昇太, 木田 博

日本呼吸器学会誌　Vol. 12　No. 増刊　p. 197-197　2023/03

分類・疫学・感染症 COVID-19の重症度における腸内細菌叢とmycobiotaの経時的変化(Taxonomy/Epidemiology/Infectious diseases Longitudinal alterations of the gut microbiota and mycobiota on COVID-19 severity)

元岡 大祐, 前田 悠一, 沖 大也, 田中 健太郎, 猪頭 英里, 平田 晴彦, 木田 博, 熊ノ郷 淳, 中村 昇太, 竹田 潔

日本細菌学雑誌　Vol. 78　No. 1　p. 40-40　2023/02

RNAダイレクトシーケンスで明らかになった腸炎ビブリオのトランスクリプトーム複雑性(Transcriptome Complexity of Vibrio parahaemolyticus revealed by direct RNA sequencing)

アルカディ・ムハッマド, 石井 英治, Dang Tat Truong, 元岡 大祐, 松田 重輝, 飯田 哲也, 児玉 年央, 奥崎 大介

日本細菌学雑誌　Vol. 78　No. 1　p. 131-131　2023/02

In vivo induction of activin A-producing alveolar macrophages supports the progression of lung cell carcinoma.

Seiji Taniguchi, Takahiro Matsui, Kenji Kimura, Soichiro Funaki, Yu Miyamoto, Yutaka Uchida, Takao Sudo, Junichi Kikuta, Tetsuya Hara, Daisuke Motooka, Yu-Chen Liu, Daisuke Okuzaki, Eiichi Morii, Noriaki Emoto, Yasushi Shintani, Masaru Ishii

Nature communications　Vol. 14　No. 1　p. 143-143　2023/01/17　Research paper (scientific journal)

Genomic repertoires linked with pathogenic potency of arthritogenic Prevotella copri isolated from the gut of patients with rheumatoid arthritis.

Takuro Nii, Yuichi Maeda, Daisuke Motooka, Mariko Naito, Yuki Matsumoto, Takao Ogawa, Eri Oguro-Igashira, Toshihiro Kishikawa, Makoto Yamashita, Satoshi Koizumi, Takashi Kurakawa, Ryu Okumura, Hisako Kayama, Mari Murakami, Taiki Sakaguchi, Bhabatosh Das, Shota Nakamura, Yukinori Okada, Atsushi Kumanogoh, Kiyoshi Takeda

Annals of the rheumatic diseases　Vol. 82　No. 5　p. 621-629　2023/01/10　Research paper (scientific journal)

Identification of a unique subset of tissue-resident memory CD4+ T cells in Crohn's disease.

Takehito Yokoi, Mari Murakami, Takako Kihara, Shigeto Seno, Mitsuru Arase, James Badger Wing, Jonas Nørskov Søndergaard, Ryuichi Kuwahara, Tomohiro Minagawa, Eri Oguro-Igashira, Daisuke Motooka, Daisuke Okuzaki, Ryota Mori, Atsuyo Ikeda, Yuki Sekido, Takahiro Amano, Hideki Iijima, Keiichi Ozono, Tsunekazu Mizushima, Seiichi Hirota, Hiroki Ikeuchi, Kiyoshi Takeda

Proceedings of the National Academy of Sciences of the United States of America　Vol. 120　No. 1　2023/01/03　Research paper (scientific journal)

Elucidating the mechanism of COVID-19 severity by integrative analyses of single-cell and host genetics data

Ryuya Edahiro, Shirai Yuya, Takeshima Yusuke, Sakakibara Shuhei, Yamaguchi Yuta, Murakami Teruaki, Morita Takayoshi, Kato Yasuhiro, Liu Yu-Chen, Motooka Daisuke, Wing James B, Sonehara Kyuto, Tomofuji Yoshihiko, Namkoong Ho, Tanaka Hiromu, Lee Ho, Fukunaga Koichi, Hirata Haruhiko, Takeda Yoshito, Okuzaki Daisuke, Kumanogoh Atsushi, Okada Yukinori

Proceedings for Annual Meeting of The Japanese Pharmacological Society　Vol. 97　2023

Prokaryotic and viral genomes recovered from 787 Japanese gut metagenomes revealed microbial features linked to diets, populations, and diseases.

Yoshihiko Tomofuji, Toshihiro Kishikawa, Yuichi Maeda, Kotaro Ogawa, Yuriko Otake-Kasamoto, Shuhei Kawabata, Takuro Nii, Tatsusada Okuno, Eri Oguro-Igashira, Makoto Kinoshita, Masatoshi Takagaki, Naoki Oyama, Kenichi Todo, Kenichi Yamamoto, Kyuto Sonehara, Mayu Yagita, Akiko Hosokawa, Daisuke Motooka, Yuki Matsumoto, Hidetoshi Matsuoka, Maiko Yoshimura, Shiro Ohshima, Shinichiro Shinzaki, Shota Nakamura, Hideki Iijima, Hidenori Inohara, Haruhiko Kishima, Tetsuo Takehara, Hideki Mochizuki, Kiyoshi Takeda, Atsushi Kumanogoh, Yukinori Okada

Cell genomics　Vol. 2　No. 12　p. 100219-100219　2022/12/14　Research paper (scientific journal)

Localization and potential role of prostate microbiota

Koichi Okada, Kentaro Takezawa, Go Tsujimura, Takahiro Imanaka, Sohei Kuribayashi, Norichika Ueda, Koji Hatano, Shinichiro Fukuhara, Hiroshi Kiuchi, Kazutoshi Fujita, Daisuke Motooka, Shota Nakamura, Yoshihisa Koyama, Shoichi Shimada, Norio Nonomura

Frontiers in Cellular and Infection Microbiology　Vol. 12　p. 1048319-1048319　2022/12/07　Research paper (scientific journal)

Prolonged gut microbial alterations in post-transplant survivors of allogeneic haematopoietic stem cell transplantation.

Akihisa Hino, Kentaro Fukushima, Shinsuke Kusakabe, Tomoaki Ueda, Takao Sudo, Jiro Fujita, Daisuke Motooka, Aya K Takeda, Natsuko O Shinozaki, Satoshi Watanabe, Takafumi Yokota, Hirohiko Shibayama, Shota Nakamura, Naoki Hosen

British journal of haematology　Vol. 201　No. 4　p. 725-737　2022/12/05　Research paper (scientific journal)

A Nationwide Plasmidome Surveillance in Thailand Reveals a Limited Variety of New Delhi Metallo-β-Lactamase-Producing Carbapenem-Resistant Enterobacteriaceae Clones and Spreading Plasmids

Ryuichiro Abe, Yukihiro Akeda, Noriko Sakamoto, Dan Takeuchi, Yo Sugawara, Norihisa Yamamoto, Anusak Kerdsin, Yuki Matsumoto, Daisuke Motooka, Warawut Laolerd, Pitak Santanirand, Masato Suzuki, Keigo Shibayama, Kazunori Tomono, Tetsuya Iida, Shigeyuki Hamada

Journal of Clinical Microbiology　Vol. 60　No. 12　2022/11/29　Research paper (scientific journal)

Metagenomic analysis of diarrheal stools in Kolkata, India, indicates the possibility of subclinical infection of Vibrio cholerae O1

Eizo Takahashi, Daisuke Motooka, Shota Nakamura, Shin-ichi Miyoshi, Goutam Chowdhury, Asish K. Mukhopadhyay, Shanta Dutta, Daichi Morita, Tetsuya Iida, Keinosuke Okamoto

Scientific Reports　Vol. 12　No. 1　p. 19473-19473　2022/11/14　Research paper (scientific journal)

Symbiotic bacteria-dependent expansion of MR1-reactive T cells causes autoimmunity in the absence of Bcl11b.

Kensuke Shibata, Chihiro Motozono, Masamichi Nagae, Takashi Shimizu, Eri Ishikawa, Daisuke Motooka, Daisuke Okuzaki, Yoshihiro Izumi, Masatomo Takahashi, Nao Fujimori, James B Wing, Takahide Hayano, Yoshiyuki Asai, Takeshi Bamba, Yoshihiro Ogawa, Makoto Furutani-Seiki, Mutsunori Shirai, Sho Yamasaki

Nature communications　Vol. 13　No. 1　p. 6948-6948　2022/11/14　Research paper (scientific journal)

Development of transgenic mice overexpressing mouse carbonyl reductase 1

Minako Yokoyama, Toshitsugu Fujita, Yuka Kadonosawa, Yota Tatara, Daisuke Motooka, Masahito Ikawa, Hodaka Fujii, Yoshihito Yokoayama

Molecular Biology Reports　Vol. 50　No. 1　p. 531-540　2022/11/09　Research paper (international conference proceedings)

Consecutive BNT162b2 mRNA vaccination induces short-term epigenetic memory in innate immune cells

Yuta Yamaguchi, Yasuhiro Kato, Ryuya Edahiro, Jonas N. Søndergaard, Teruaki Murakami, Saori Amiya, Shinichiro Nameki, Yuko Yoshimine, Takayoshi Morita, Yusuke Takeshima, Shuhei Sakakibara, Yoko Naito, Daisuke Motooka, Yu-Chen Liu, Yuya Shirai, Yasutaka Okita, Jun Fujimoto, Haruhiko Hirata, Yoshito Takeda, James B. Wing, Daisuke Okuzaki, Yukinori Okada, Atsushi Kumanogoh

JCI Insight　Vol. 7　No. 22　2022/10/25　Research paper (scientific journal)

Intraocular human cytomegaloviruses of ocular diseases are distinct from those of viremia and are capable of escaping from innate and adaptive immunity by exploiting HLA-E-mediated peripheral and central tolerance.

Mariko Shirane, Nobuyo Yawata, Daisuke Motooka, Kensuke Shibata, Seik-Soon Khor, Yosuke Omae, Toshikatsu Kaburaki, Ryoji Yanai, Hisashi Mashimo, Satoshi Yamana, Takako Ito, Akira Hayashida, Yasuo Mori, Akihiko Numata, Yusuke Murakami, Kohta Fujiwara, Nobuyuki Ohguro, Mayumi Hosogai, Masato Akiyama, Eiichi Hasegawa, Michael Paley, Atsunobu Takeda, Katsumi Maenaka, Koichi Akashi, Wayne M Yokoyama, Katsushi Tokunaga, Makoto Yawata, Koh-Hei Sonoda

Frontiers in immunology　Vol. 13　p. 1008220-1008220　2022/10/19　Research paper (scientific journal)

Multiple orthokeratinized odontogenic cysts: clinical, pathological, and genetic characteristics.

Sawako Ono, Katsutoshi Hirose, Shintaro Sukegawa, Satoko Nakamura, Daisuke Motooka, Yuri Iwamoto, Yumiko Hori, Kaori Oya, Yasuo Fukuda, Satoru Toyosawa

Diagnostic pathology　Vol. 17　No. 1　p. 82-82　2022/10/14　Research paper (scientific journal)

Myeloid cell-specific ablation of Runx2 gene exacerbates post-infarct cardiac remodeling.

Masashi Tomimatsu, Kotaro Matsumoto, Moe Ashizuka, Shohei Kumagai, Shota Tanaka, Takafumi Nakae, Kosei Yokota, Shunsuke Kominami, Ryota Kajiura, Daisuke Okuzaki, Daisuke Motooka, Aki Shiraishi, Takaya Abe, Hideo Matsuda, Yoshiaki Okada, Makiko Maeda, Shigeto Seno, Masanori Obana, Yasushi Fujio

Scientific reports　Vol. 12　No. 1　p. 16656-16656　2022/10/05　Research paper (scientific journal)

A heterozygous LAMA5 variant may contribute to slowly progressive, vinculin-enhanced familial FSGS and pulmonary defects.

Jun-Ya Kaimori, Yamato Kikkawa, Daisuke Motooka, Tomoko Namba-Hamano, Ayako Takuwa, Atsuko Imai-Okazaki, Kaori Kobayashi, Arisa Tanigawa, Yuko Kotani, Yoshihiro Uno, Kazuto Yoshimi, Koki Hattori, Yuta Asahina, Sachio Kajimoto, Yohei Doi, Tatsufumi Oka, Yusuke Sakaguchi, Tomoji Mashimo, Kiyotoshi Sekiguchi, Akihiro Nakaya, Motoyoshi Nomizu, Yoshitaka Isaka

JCI insight　Vol. 7　No. 23　2022/09/29　Research paper (scientific journal)

A fatal case of hemophagocytic lymphohistiocytosis associated with gestational psittacosis without symptoms of pneumonia.

Michinobu Yoshimura, Kanako Shimizu, Yukiko Nakura, Kazumi Kawahara, Harutaka Katano, Daisuke Motooka, Makoto Takeuchi, Kisaburo Nagamune, Yoshiaki Imamura, Shota Nakamura, Kiyoshi Yasukawa, Hideki Hasegawa, Yoshio Yoshida, Itaru Yanagihara

The journal of obstetrics and gynaecology research　Vol. 48　No. 12　p. 3325-3330　2022/09/12　Research paper (scientific journal)

腸内細菌叢由来LPSはヒスタミンH1受容体シグナル経路を介して前立腺癌増殖を促進する(Lipopolysaccharide from gut microhiota promotes prostate cancer growth through histamine III receptor signaling)

藤田 和利, 松下 慎, 元岡 大祐, 長谷 拓明, 加藤 大悟, 波多野 浩士, 河嶋 厚成, 南 高文, マルコ・デベラスコ, 吉村 一宏, ジョージ・ネットー, 辻川 和丈, 中村 昇太, 森井 英一, 植村 天受, 野々村 祝夫

日本癌学会総会記事　Vol. 81回　p. E-3077　2022/09

Streptococcus pneumoniaeによる肺炎において加齢が重症化に果たす機構の解明(Elucidation of the mechanism by which aging plays a role in the severity of pneumococcal pneumonia)

山口 雅也, 小林 桃子, 大野 誠之, 川端 重忠, 川西 邦夫, 元岡 大祐, 奥崎 大介

Journal of Oral Biosciences Supplement　Vol. 2022　p. 119-119　2022/09

Inhibition of nonhomologous end joining-mediated DNA repair enhances anti-HBV CRISPR therapy.

Kazuhiro Murai, Takahiro Kodama, Hayato Hikita, Akiyoshi Shimoda, Makoto Fukuoka, Keisuke Fukutomi, Satoshi Shigeno, Yuto Shiode, Daisuke Motooka, Yuichiro Higuchi, Kei Miyakawa, Hiroshi Suemizu, Akihide Ryo, Yuki Tahata, Yuki Makino, Ryoko Yamada, Ryotaro Sakamori, Tomohide Tatsumi, Tetsuo Takehara

Hepatology communications　Vol. 6　No. 9　p. 2474-2487　2022/09/01　Research paper (scientific journal)

DOCK2 is involved in the host genetics and biology of severe COVID-19.

Ho Namkoong, Ryuya Edahiro, Tomomi Takano, Hiroshi Nishihara, Yuya Shirai, Kyuto Sonehara, Hiromu Tanaka, Shuhei Azekawa, Yohei Mikami, Ho Lee, Takanori Hasegawa, Koji Okudela, Daisuke Okuzaki, Daisuke Motooka, Masahiro Kanai, Tatsuhiko Naito, Kenichi Yamamoto, Qingbo S Wang, Ryunosuke Saiki, Rino Ishihara, Yuta Matsubara, Junko Hamamoto, Hiroyuki Hayashi, Yukihiro Yoshimura, Natsuo Tachikawa, Emmy Yanagita, Takayoshi Hyugaji, Eigo Shimizu, Kotoe Katayama, Yasuhiro Kato, Takayoshi Morita, Kazuhisa Takahashi, Norihiro Harada, Toshio Naito, Makoto Hiki, Yasushi Matsushita, Haruhi Takagi, Ryousuke Aoki, Ai Nakamura, Sonoko Harada, Hitoshi Sasano, Hiroki Kabata, Katsunori Masaki, Hirofumi Kamata, Shinnosuke Ikemura, Shotaro Chubachi, Satoshi Okamori, Hideki Terai, Atsuho Morita, Takanori Asakura, Junichi Sasaki, Hiroshi Morisaki, Yoshifumi Uwamino, Kosaku Nanki, Sho Uchida, Shunsuke Uno, Tomoyasu Nishimura, Takashi Ishiguro, Taisuke Isono, Shun Shibata, Yuma Matsui, Chiaki Hosoda, Kenji Takano, Takashi Nishida, Yoichi Kobayashi, Yotaro Takaku, Noboru Takayanagi, Soichiro Ueda, Ai Tada, Masayoshi Miyawaki, Masaomi Yamamoto, Eriko Yoshida, Reina Hayashi, Tomoki Nagasaka, Sawako Arai, Yutaro Kaneko, Kana Sasaki, Etsuko Tagaya, Masatoshi Kawana, Ken Arimura, Kunihiko Takahashi, Tatsuhiko Anzai, Satoshi Ito, Akifumi Endo, Yuji Uchimura, Yasunari Miyazaki, Takayuki Honda, Tomoya Tateishi, Shuji Tohda, Naoya Ichimura, Kazunari Sonobe, Chihiro Tani Sassa, Jun Nakajima, Yasushi Nakano, Yukiko Nakajima, Ryusuke Anan, Ryosuke Arai, Yuko Kurihara, Yuko Harada, Kazumi Nishio, Tetsuya Ueda, Masanori Azuma, Ryuichi Saito, Toshikatsu Sado, Yoshimune Miyazaki, Ryuichi Sato, Yuki Haruta, Tadao Nagasaki, Yoshinori Yasui, Yoshinori Hasegawa, Yoshikazu Mutoh, Tomoki Kimura, Tomonori Sato, Reoto Takei, Satoshi Hagimoto, Yoichiro Noguchi, Yasuhiko Yamano, Hajime Sasano, Sho Ota, Yasushi Nakamori, Kazuhisa Yoshiya, Fukuki Saito, Tomoyuki Yoshihara, Daiki Wada, Hiromu Iwamura, Syuji Kanayama, Shuhei Maruyama, Takashi Yoshiyama, Ken Ohta, Hiroyuki Kokuto, Hideo Ogata, Yoshiaki Tanaka, Kenichi Arakawa, Masafumi Shimoda, Takeshi Osawa, Hiroki Tateno, Isano Hase, Shuichi Yoshida, Shoji Suzuki, Miki Kawada, Hirohisa Horinouchi, Fumitake Saito, Keiko Mitamura, Masao Hagihara, Junichi Ochi, Tomoyuki Uchida, Rie Baba, Daisuke Arai, Takayuki Ogura, Hidenori Takahashi, Shigehiro Hagiwara, Genta Nagao, Shunichiro Konishi, Ichiro Nakachi, Koji Murakami, Mitsuhiro Yamada, Hisatoshi Sugiura, Hirohito Sano, Shuichiro Matsumoto, Nozomu Kimura, Yoshinao Ono, Hiroaki Baba, Yusuke Suzuki, Sohei Nakayama, Keita Masuzawa, Shinichi Namba, Ken Suzuki, Yoko Naito, Yu-Chen Liu, Ayako Takuwa, Fuminori Sugihara, James B Wing, Shuhei Sakakibara, Nobuyuki Hizawa, Takayuki Shiroyama, Satoru Miyawaki, Yusuke Kawamura, Akiyoshi Nakayama, Hirotaka Matsuo, Yuichi Maeda, Takuro Nii, Yoshimi Noda, Takayuki Niitsu, Yuichi Adachi, Takatoshi Enomoto, Saori Amiya, Reina Hara, Yuta Yamaguchi, Teruaki Murakami, Tomoki Kuge, Kinnosuke Matsumoto, Yuji Yamamoto, Makoto Yamamoto, Midori Yoneda, Toshihiro Kishikawa, Shuhei Yamada, Shuhei Kawabata, Noriyuki Kijima, Masatoshi Takagaki, Noah Sasa, Yuya Ueno, Motoyuki Suzuki, Norihiko Takemoto, Hirotaka Eguchi, Takahito Fukusumi, Takao Imai, Munehisa Fukushima, Haruhiko Kishima, Hidenori Inohara, Kazunori Tomono, Kazuto Kato, Meiko Takahashi, Fumihiko Matsuda, Haruhiko Hirata, Yoshito Takeda, Hidefumi Koh, Tadashi Manabe, Yohei Funatsu, Fumimaro Ito, Takahiro Fukui, Keisuke Shinozuka, Sumiko Kohashi, Masatoshi Miyazaki, Tomohisa Shoko, Mitsuaki Kojima, Tomohiro Adachi, Motonao Ishikawa, Kenichiro Takahashi, Takashi Inoue, Toshiyuki Hirano, Keigo Kobayashi, Hatsuyo Takaoka, Kazuyoshi Watanabe, Naoki Miyazawa, Yasuhiro Kimura, Reiko Sado, Hideyasu Sugimoto, Akane Kamiya, Naota Kuwahara, Akiko Fujiwara, Tomohiro Matsunaga, Yoko Sato, Takenori Okada, Yoshihiro Hirai, Hidetoshi Kawashima, Atsuya Narita, Kazuki Niwa, Yoshiyuki Sekikawa, Koichi Nishi, Masaru Nishitsuji, Mayuko Tani, Junya Suzuki, Hiroki Nakatsumi, Takashi Ogura, Hideya Kitamura, Eri Hagiwara, Kota Murohashi, Hiroko Okabayashi, Takao Mochimaru, Shigenari Nukaga, Ryosuke Satomi, Yoshitaka Oyamada, Nobuaki Mori, Tomoya Baba, Yasutaka Fukui, Mitsuru Odate, Shuko Mashimo, Yasushi Makino, Kazuma Yagi, Mizuha Hashiguchi, Junko Kagyo, Tetsuya Shiomi, Satoshi Fuke, Hiroshi Saito, Tomoya Tsuchida, Shigeki Fujitani, Mumon Takita, Daiki Morikawa, Toru Yoshida, Takehiro Izumo, Minoru Inomata, Naoyuki Kuse, Nobuyasu Awano, Mari Tone, Akihiro Ito, Yoshihiko Nakamura, Kota Hoshino, Junichi Maruyama, Hiroyasu Ishikura, Tohru Takata, Toshio Odani, Masaru Amishima, Takeshi Hattori, Yasuo Shichinohe, Takashi Kagaya, Toshiyuki Kita, Kazuhide Ohta, Satoru Sakagami, Kiyoshi Koshida, Kentaro Hayashi, Tetsuo Shimizu, Yutaka Kozu, Hisato Hiranuma, Yasuhiro Gon, Namiki Izumi, Kaoru Nagata, Ken Ueda, Reiko Taki, Satoko Hanada, Kodai Kawamura, Kazuya Ichikado, Kenta Nishiyama, Hiroyuki Muranaka, Kazunori Nakamura, Naozumi Hashimoto, Keiko Wakahara, Koji Sakamoto, Norihito Omote, Akira Ando, Nobuhiro Kodama, Yasunari Kaneyama, Shunsuke Maeda, Takashige Kuraki, Takemasa Matsumoto, Koutaro Yokote, Taka-Aki Nakada, Ryuzo Abe, Taku Oshima, Tadanaga Shimada, Masahiro Harada, Takeshi Takahashi, Hiroshi Ono, Toshihiro Sakurai, Takayuki Shibusawa, Yoshifumi Kimizuka, Akihiko Kawana, Tomoya Sano, Chie Watanabe, Ryohei Suematsu, Hisako Sageshima, Ayumi Yoshifuji, Kazuto Ito, Saeko Takahashi, Kota Ishioka, Morio Nakamura, Makoto Masuda, Aya Wakabayashi, Hiroki Watanabe, Suguru Ueda, Masanori Nishikawa, Yusuke Chihara, Mayumi Takeuchi, Keisuke Onoi, Jun Shinozuka, Atsushi Sueyoshi, Yoji Nagasaki, Masaki Okamoto, Sayoko Ishihara, Masatoshi Shimo, Yoshihisa Tokunaga, Yu Kusaka, Takehiko Ohba, Susumu Isogai, Aki Ogawa, Takuya Inoue, Satoru Fukuyama, Yoshihiro Eriguchi, Akiko Yonekawa, Keiko Kan-O, Koichiro Matsumoto, Kensuke Kanaoka, Shoichi Ihara, Kiyoshi Komuta, Yoshiaki Inoue, Shigeru Chiba, Kunihiro Yamagata, Yuji Hiramatsu, Hirayasu Kai, Koichiro Asano, Tsuyoshi Oguma, Yoko Ito, Satoru Hashimoto, Masaki Yamasaki, Yu Kasamatsu, Yuko Komase, Naoya Hida, Takahiro Tsuburai, Baku Oyama, Minoru Takada, Hidenori Kanda, Yuichiro Kitagawa, Tetsuya Fukuta, Takahito Miyake, Shozo Yoshida, Shinji Ogura, Shinji Abe, Yuta Kono, Yuki Togashi, Hiroyuki Takoi, Ryota Kikuchi, Shinichi Ogawa, Tomouki Ogata, Shoichiro Ishihara, Arihiko Kanehiro, Shinji Ozaki, Yasuko Fuchimoto, Sae Wada, Nobukazu Fujimoto, Kei Nishiyama, Mariko Terashima, Satoru Beppu, Kosuke Yoshida, Osamu Narumoto, Hideaki Nagai, Nobuharu Ooshima, Mitsuru Motegi, Akira Umeda, Kazuya Miyagawa, Hisato Shimada, Mayu Endo, Yoshiyuki Ohira, Masafumi Watanabe, Sumito Inoue, Akira Igarashi, Masamichi Sato, Hironori Sagara, Akihiko Tanaka, Shin Ohta, Tomoyuki Kimura, Yoko Shibata, Yoshinori Tanino, Takefumi Nikaido, Hiroyuki Minemura, Yuki Sato, Yuichiro Yamada, Takuya Hashino, Masato Shinoki, Hajime Iwagoe, Hiroshi Takahashi, Kazuhiko Fujii, Hiroto Kishi, Masayuki Kanai, Tomonori Imamura, Tatsuya Yamashita, Masakiyo Yatomi, Toshitaka Maeno, Shinichi Hayashi, Mai Takahashi, Mizuki Kuramochi, Isamu Kamimaki, Yoshiteru Tominaga, Tomoo Ishii, Mitsuyoshi Utsugi, Akihiro Ono, Toru Tanaka, Takeru Kashiwada, Kazue Fujita, Yoshinobu Saito, Masahiro Seike, Hiroko Watanabe, Hiroto Matsuse, Norio Kodaka, Chihiro Nakano, Takeshi Oshio, Takatomo Hirouchi, Shohei Makino, Moritoki Egi, Yosuke Omae, Yasuhito Nannya, Takafumi Ueno, Kazuhiko Katayama, Masumi Ai, Yoshinori Fukui, Atsushi Kumanogoh, Toshiro Sato, Naoki Hasegawa, Katsushi Tokunaga, Makoto Ishii, Ryuji Koike, Yuko Kitagawa, Akinori Kimura, Seiya Imoto, Satoru Miyano, Seishi Ogawa, Takanori Kanai, Koichi Fukunaga, Yukinori Okada

Nature　Vol. 609　No. 7928　p. 754-760　2022/09/01　Research paper (scientific journal)

Multiple knockout mouse and embryonic stem cell models reveal the role of miR-124a in neuronal maturation.

Taro Chaya, Yamato Maeda, Ryo Sugimura, Daisuke Okuzaki, Satoshi Watanabe, Leah R Varner, Daisuke Motooka, Daichi Gyoten, Haruka Yamamoto, Hidemasa Kato, Takahisa Furukawa

The Journal of biological chemistry　Vol. 298　No. 9　p. 102293-102293　2022/09/01　Research paper (scientific journal)

Establishment of a reference single-cell RNA sequencing dataset for human pancreatic adenocarcinoma.

Ryota Chijimatsu, Shogo Kobayashi, Yu Takeda, Masatoshi Kitakaze, Shotaro Tatekawa, Yasuko Arao, Mika Nakayama, Naohiro Tachibana, Taku Saito, Daisuke Ennishi, Shuta Tomida, Kazuki Sasaki, Daisaku Yamada, Yoshito Tomimaru, Hidenori Takahashi, Daisuke Okuzaki, Daisuke Motooka, Takahito Ohshiro, Masateru Taniguchi, Yutaka Suzuki, Kazuhiko Ogawa, Masaki Mori, Yuichiro Doki, Hidetoshi Eguchi, Hideshi Ishii

iScience　Vol. 25　No. 8　p. 104659-104659　2022/08/19　Research paper (scientific journal)

High-fat diet promotes prostate cancer growth through histamine signaling.

Makoto Matsushita, Kazutoshi Fujita, Koji Hatano, Takuji Hayashi, Hisako Kayama, Daisuke Motooka, Hiroaki Hase, Akinaru Yamamoto, Toshihiko Uemura, Gaku Yamamichi, Eisuke Tomiyama, Yoko Koh, Taigo Kato, Atsunari Kawashima, Motohide Uemura, Satoshi Nojima, Ryoichi Imamura, Aysha Mubeen, George J Netto, Kazutake Tsujikawa, Shota Nakamura, Kiyoshi Takeda, Eiichi Morii, Norio Nonomura

International journal of cancer　Vol. 151　No. 4　p. 623-636　2022/08/15　Research paper (scientific journal)

腸内細菌による前立腺癌増殖制御メカニズムの解明

松下 慎, 藤田 和利, 林 拓自, 香山 尚子, 元岡 大祐, 長谷 拓明, 神宮司 健太郎, 山本 顕生, 植村 俊彦, 山道 岳, 冨山 栄輔, 洪 陽子, 加藤 大悟, 波多野 浩士, 河嶋 厚成, 植村 元秀, 今村 亮一, 辻川 和丈, 中村 昇太, 竹田 潔, 野々村 祝夫

泌尿器外科　Vol. 35　No. 8　p. 858-859　2022/08

腸内細菌による前立腺癌増殖制御メカニズムの解明

松下 慎, 藤田 和利, 林 拓自, 香山 尚子, 元岡 大祐, 長谷 拓明, 神宮司 健太郎, 山本 顕生, 植村 俊彦, 山道 岳, 冨山 栄輔, 洪 陽子, 加藤 大悟, 波多野 浩士, 河嶋 厚成, 植村 元秀, 今村 亮一, 辻川 和丈, 中村 昇太, 竹田 潔, 野々村 祝夫

泌尿器外科　Vol. 35　No. 8　p. 858-859　2022/08

Role of Chromosome- and/or Plasmid-Located bla<inf>NDM</inf> on the Carbapenem Resistance and the Gene Stability in Escherichia coli

Noriko Sakamoto, Yukihiro Akeda, Yo Sugawara, Yuki Matsumoto, Daisuke Motooka, Tetsuya Iida, Shigeyuki Hamada

Microbiology Spectrum　Vol. 10　No. 4　2022/08/01　Research paper (scientific journal)

Exacerbation of non-steroidal anti-inflammatory drug-induced enteropathy in C-C chemokine receptor type 7-deficient mice.

Toshio Yamaguchi, Hideki Iijima, Takeo Yoshihara, Mizuki Tani, Yuriko Otake, Shuko Iwatani, Takahiro Amano, Taku Tashiro, Tomohide Kurahashi, Takanori Inoue, Yoshiki Tsujii, Yoshito Hayashi, Takahiro Inoue, Daisuke Motooka, Shota Nakamura, Shinichiro Shinzaki, Tetsuo Takehara

Journal of gastroenterology and hepatology　Vol. 37　No. 8　p. 1561-1570　2022/08/01　Research paper (scientific journal)

Clonal dissemination of carbapenem-resistant Klebsiella pneumoniae ST16 co-producing NDM-1 and OXA-232 in Thailand.

Ryuichiro Abe, Yukihiro Akeda, Dan Takeuchi, Noriko Sakamoto, Yo Sugawara, Norihisa Yamamoto, Anusak Kerdsin, Yuki Matsumoto, Daisuke Motooka, Warawut Leolerd, Pitak Santanirand, Masato Suzuki, Keigo Shibayama, Kazunori Tomono, Tetsuya Iida, Shigeyuki Hamada

JAC-antimicrobial resistance　Vol. 4　No. 4　2022/08/01　Research paper (scientific journal)

Myasthenia gravis-specific aberrant neuromuscular gene expression by medullary thymic epithelial cells in thymoma.

Yoshiaki Yasumizu, Naganari Ohkura, Hisashi Murata, Makoto Kinoshita, Soichiro Funaki, Satoshi Nojima, Kansuke Kido, Masaharu Kohara, Daisuke Motooka, Daisuke Okuzaki, Shuji Suganami, Eriko Takeuchi, Yamami Nakamura, Yusuke Takeshima, Masaya Arai, Satoru Tada, Meinoshin Okumura, Eiichi Morii, Yasushi Shintani, Shimon Sakaguchi, Tatsusada Okuno, Hideki Mochizuki

Nature communications　Vol. 13　No. 1　p. 4230-4230　2022/07/22　Research paper (scientific journal)

Circulating Cell-Free DNA Profiling Predicts the Therapeutic Outcome in Advanced Hepatocellular Carcinoma Patients Treated with Combination Immunotherapy.

Takayuki Matsumae, Takahiro Kodama, Yuta Myojin, Kazuki Maesaka, Ryotaro Sakamori, Ayako Takuwa, Keiko Oku, Daisuke Motooka, Yoshiyuki Sawai, Masahide Oshita, Tasuku Nakabori, Kazuyoshi Ohkawa, Masanori Miyazaki, Satoshi Tanaka, Eiji Mita, Seiichi Tawara, Takayuki Yakushijin, Yasutoshi Nozaki, Hideki Hagiwara, Yuki Tahata, Ryoko Yamada, Hayato Hikita, Tomohide Tatsumi, Tetsuo Takehara

Cancers　Vol. 14　No. 14　2022/07/11　Research paper (scientific journal)

Lysophosphatidylserines derived from microbiota in Crohn's disease elicit pathological Th1 response.

Yuriko Otake-Kasamoto, Hisako Kayama, Toshihiro Kishikawa, Shinichiro Shinzaki, Taku Tashiro, Takahiro Amano, Mizuki Tani, Takeo Yoshihara, Bo Li, Haruka Tani, Li Liu, Akio Hayashi, Daisuke Okuzaki, Daisuke Motooka, Shota Nakamura, Yukinori Okada, Hideki Iijima, Kiyoshi Takeda, Tetsuo Takehara

The Journal of experimental medicine　Vol. 219　No. 7　2022/07/04　Research paper (scientific journal)

Chronic Pulmonary Disease Caused by Tsukamurella toyonakaense.

Tomoki Kuge, Kiyoharu Fukushima, Yuki Matsumoto, Haruko Saito, Yuko Abe, Eri Akiba, Kako Haduki, Tadayoshi Nitta, Akira Kawano, Michio Tanaka, Yumi Hattori, Takahiro Kawasaki, Takanori Matsuki, Takayuki Shiroyama, Daisuke Motooka, Kazuyuki Tsujino, Keisuke Miki, Masahide Mori, Seigo Kitada, Shota Nakamura, Tetsuya Iida, Atsushi Kumanogoh, Hiroshi Kida

Emerging infectious diseases　Vol. 28　No. 7　p. 1437-1441　2022/07/01　Research paper (scientific journal)

Pneumococcal BgaA Promotes Host Organ Bleeding and Coagulation in a Mouse Sepsis Model.

Moe Takemura, Masaya Yamaguchi, Momoko Kobayashi, Tomoko Sumitomo, Yujiro Hirose, Daisuke Okuzaki, Masayuki Ono, Daisuke Motooka, Kana Goto, Masanobu Nakata, Narikazu Uzawa, Shigetada Kawabata

Frontiers in cellular and infection microbiology　Vol. 12　p. 844000-844000　2022/07/01　Research paper (scientific journal)

Firmicutes in Gut Microbiota Correlate with Blood Testosterone Levels in Elderly Men.

Makoto Matsushita, Kazutoshi Fujita, Daisuke Motooka, Koji Hatano, Junya Hata, Mitsuhisa Nishimoto, Eri Banno, Kentaro Takezawa, Shinichiro Fukuhara, Hiroshi Kiuchi, Yue Pan, Toshifumi Takao, Akira Tsujimura, Shinichi Yachida, Shota Nakamura, Wataru Obara, Hirotsugu Uemura, Norio Nonomura

The world journal of men's health　Vol. 40　No. 3　p. 517-525　2022/07/01　Research paper (scientific journal)

N(6)-methyladenosine methylation-regulated polo-like kinase 1 cell cycle homeostasis as a potential target of radiotherapy in pancreatic adenocarcinoma.

Shotaro Tatekawa, Keisuke Tamari, Ryota Chijimatsu, Masamitsu Konno, Daisuke Motooka, Suguru Mitsufuji, Hirofumi Akita, Shogo Kobayashi, Yoshiki Murakumo, Yuichiro Doki, Hidetoshi Eguchi, Hideshi Ishii, Kazuhiko Ogawa

Scientific reports　Vol. 12　No. 1　p. 11074-11074　2022/06/30　Research paper (scientific journal)

Longitudinal alterations of the gut mycobiota and microbiota on COVID-19 severity.

Yuichi Maeda, Daisuke Motooka, Takahiro Kawasaki, Hiroya Oki, Yoshimi Noda, Yuichi Adachi, Takayuki Niitsu, Shota Okamoto, Kentaro Tanaka, Kiyoharu Fukushima, Saori Amiya, Reina Hara, Eri Oguro-Igashira, Takanori Matsuki, Haruhiko Hirata, Yoshito Takeda, Hiroshi Kida, Atsushi Kumanogoh, Shota Nakamura, Kiyoshi Takeda

BMC infectious diseases　Vol. 22　No. 1　p. 572-572　2022/06/24　Research paper (scientific journal)

An engineered ACE2 decoy neutralizes the SARS-CoV-2 Omicron variant and confers protection against infection in vivo.

Nariko Ikemura, Shunta Taminishi, Tohru Inaba, Takao Arimori, Daisuke Motooka, Kazutaka Katoh, Yuhei Kirita, Yusuke Higuchi, Songling Li, Tatsuya Suzuki, Yumi Itoh, Yuki Ozaki, Shota Nakamura, Satoaki Matoba, Daron M Standley, Toru Okamoto, Junichi Takagi, Atsushi Hoshino

Science translational medicine　Vol. 14　No. 650　2022/06/22　Research paper (scientific journal)

次世代シーケンサーMinIONを用いた抗酸菌リアルタイム同定システムの開発

松本 悠希, 福島 清春, 元岡 大祐, 金城 武士, 木田 博, 中村 昇太

結核　Vol. 97　No. 4　p. 118-118　2022/06

Metagenomic identification of pathogenic bacteria for pneumonia from postmortem lung tissue

Hidenori Yoshizawa, Daisuke Motooka, Shota Nakamura, Ken ichi Yoshida

Human Pathology Reports　Vol. 28　2022/06/01　Research paper (scientific journal)

Bile Collected From the Normal Gallbladder of Patients During Surgery Has Simple Bacterial Flora.

Shin Watanabe, Masaaki Minagawa, Tadashi Shinoda, Daisuke Motooka, Mari Tohya, Teruo Kirikae, Shota Nakamura, Akio Saiura

Cureus　Vol. 14　No. 6　2022/06　Research paper (scientific journal)

Cell response analysis in SARS-CoV-2 infected bronchial organoids.

Emi Sano, Tatsuya Suzuki, Rina Hashimoto, Yumi Itoh, Ayaka Sakamoto, Yusuke Sakai, Akatsuki Saito, Daisuke Okuzaki, Daisuke Motooka, Yukiko Muramoto, Takeshi Noda, Tomohiko Takasaki, Jun-Ichi Sakuragi, Shohei Minami, Takeshi Kobayashi, Takuya Yamamoto, Yasufumi Matsumura, Miki Nagao, Toru Okamoto, Kazuo Takayama

Communications biology　Vol. 5　No. 1　p. 516-516　2022/05/30　Research paper (scientific journal)

Circulating extracellular vesicles carrying Firmicutes reflective of the local immune status may predict clinical response to pembrolizumab in urothelial carcinoma patients.

Kentaro Jingushi, Atsunari Kawashima, Takuro Saito, Takayuki Kanazawa, Daisuke Motooka, Tomonori Kimura, Masashi Mita, Akinaru Yamamoto, Toshihiro Uemura, Gaku Yamamichi, Koichi Okada, Eisuke Tomiyama, Yoko Koh, Makoto Matsushita, Taigo Kato, Koji Hatano, Motohide Uemura, Kazutake Tsujikawa, Hisashi Wada, Norio Nonomura

Cancer immunology, immunotherapy : CII　Vol. 71　No. 12　p. 2999-3011　2022/05/22　Research paper (scientific journal)

Multiomics identifies the link between intratumor steatosis and the exhausted tumor immune microenvironment in hepatocellular carcinoma.

Hiroki Murai, Takahiro Kodama, Kazuki Maesaka, Shoichiro Tange, Daisuke Motooka, Yutaka Suzuki, Yasuyuki Shigematsu, Kentaro Inamura, Yoshihiro Mise, Akio Saiura, Yoshihiro Ono, Yu Takahashi, Yota Kawasaki, Satoshi Iino, Shogo Kobayashi, Masashi Idogawa, Takashi Tokino, Tomomi Hashidate-Yoshida, Hideo Shindou, Masanori Miyazaki, Yasuharu Imai, Satoshi Tanaka, Eiji Mita, Kazuyoshi Ohkawa, Hayato Hikita, Ryotaro Sakamori, Tomohide Tatsumi, Hidetoshi Eguchi, Eiichi Morii, Tetsuo Takehara

Hepatology (Baltimore, Md.)　Vol. 77　No. 1　p. 77-91　2022/05/14　Research paper (scientific journal)

Mycobacterium senriense sp. nov., a slowly growing, non-scotochromogenic species, isolated from sputum of an elderly man.

Yuko Abe, Kiyoharu Fukushima, Yuki Matsumoto, Takayuki Niitsu, Hiroshi Nabeshima, Yasuharu Nagahama, Eri Akiba, Kako Haduki, Haruko Saito, Tadayoshi Nitta, Akira Kawano, Michio Tanaka, Takanori Matsuki, Daisuke Motooka, Kazuyuki Tsujino, Keisuke Miki, Shota Nakamura, Tetsuya Iida, Hiroshi Kida

International journal of systematic and evolutionary microbiology　Vol. 72　No. 5　2022/05/01　Research paper (scientific journal)

Cell-Free DNA Derived From Neutrophils Triggers Type 1 Interferon Signature in Neuromyelitis Optica Spectrum Disorder.

Hisashi Murata, Makoto Kinoshita, Yoshiaki Yasumizu, Daisuke Motooka, Shohei Beppu, Naoyuki Shiraishi, Yasuko Sugiyama, Keigo Kihara, Satoru Tada, Toru Koda, Hachiro Konaka, Hyota Takamatsu, Atsushi Kumanogoh, Tatsusada Okuno, Hideki Mochizuki

Neurology(R) neuroimmunology & neuroinflammation　Vol. 9　No. 3　2022/05/01　Research paper (scientific journal)

リアルタイムコアゲノム解析による非結核性抗酸菌症の迅速・高精度同定法の確立および臨床応用

新津 敬之, 福島 清春, 松本 悠希, 安部 祐子, 新居 卓朗, 木庭 太郎, 松木 隆典, 元岡 大祐, 辻野 和之, 三木 啓資, 中村 昇太, 木田 博

日本呼吸器学会誌　Vol. 11　No. 増刊　p. 312-312　2022/04

Nationwide surveillance in Thailand revealed genotype-dependent dissemination of carbapenem-resistant Enterobacterales.

Dan Takeuchi, Anusak Kerdsin, Yukihiro Akeda, Yo Sugawara, Noriko Sakamoto, Yuki Matsumoto, Daisuke Motooka, Takuma Ishihara, Isao Nishi, Warawut Laolerd, Pitak Santanirand, Norihisa Yamamoto, Kazunori Tomono, Shigeyuki Hamada

Microbial genomics　Vol. 8　No. 4　2022/04/01　Research paper (scientific journal)

Epithelial miR-215 negatively modulates Th17-dominant inflammation by inhibiting CXCL12 production in the small intestine.

Siddhika Pareek, Xenia Sanchenkova, Taiki Sakaguchi, Mari Murakami, Ryu Okumura, Hisako Kayama, Saya Kawauchi, Daisuke Motooka, Shota Nakamura, Daisuke Okuzaki, Tadamitsu Kishimoto, Kiyoshi Takeda

Genes to cells : devoted to molecular & cellular mechanisms　Vol. 27　No. 4　p. 243-253　2022/04/01　Research paper (scientific journal)

Multiple tolerance checkpoints restrain affinity maturation of B cells expressing the germline precursor of a lupus patient-derived anti-dsDNA antibody in knock-in mice.

Marwa Ali El Hussien, Chao-Yuan Tsai, Yuhkoh Satouh, Daisuke Motooka, Daisuke Okuzaki, Masahito Ikawa, Hitoshi Kikutani, Shuhei Sakakibara

International immunology　Vol. 34　No. 4　p. 207-223　2022/03/25　Research paper (scientific journal)

Analysis of the complete genome sequences of Clostridium perfringens strains harbouring the binary enterotoxin BEC gene and comparative genomics of pCP13-like family plasmids.

Kengo Ueda, Kazuki Kawahara, Narumi Kimoto, Yusuke Yamaguchi, Kazuhiro Yamada, Hiroya Oki, Takuya Yoshida, Shigeaki Matsuda, Yuki Matsumoto, Daisuke Motooka, Kentaro Kawatsu, Tetsuya Iida, Shota Nakamura, Tadayasu Ohkubo, Shinya Yonogi

BMC genomics　Vol. 23　No. 1　p. 226-226　2022/03/23　Research paper (scientific journal)

空間的トランスクリプトーム解析を用いた炎症関連瘢痕形成遺伝子の同定及び機能解析

森 亮一, 金 湘殷, Liu Yu-Chen, 亀岡 章一郎, 福田 茉莉, 元岡 大祐, 奥崎 大介, 下川 功

日本病理学会会誌　Vol. 111　No. 1　p. 215-215　2022/03

Dysbiosis of Gut Microbiome Is Associated With Rupture of Cerebral Aneurysms.

Shuhei Kawabata, Masatoshi Takagaki, Hajime Nakamura, Hiroya Oki, Daisuke Motooka, Shota Nakamura, Takeo Nishida, Eisaku Terada, Nobuyuki Izutsu, Tomofumi Takenaka, Yuichi Matsui, Shuhei Yamada, Katsunori Asai, Akihiro Tateishi, Toru Umehara, Yoshihiro Yano, Yohei Bamba, Katsumi Matsumoto, Toshihiro Kishikawa, Yukinori Okada, Tetsuya Iida, Haruhiko Kishima

Stroke　Vol. 53　No. 3　p. 895-903　2022/03/01　Research paper (scientific journal)

Osteoblast-derived vesicles induce a switch from bone-formation to bone-resorption in vivo.

Maki Uenaka, Erika Yamashita, Junichi Kikuta, Akito Morimoto, Tomoka Ao, Hiroki Mizuno, Masayuki Furuya, Tetsuo Hasegawa, Hiroyuki Tsukazaki, Takao Sudo, Keizo Nishikawa, Daisuke Okuzaki, Daisuke Motooka, Nobuyoshi Kosaka, Fuminori Sugihara, Thomas Boettger, Thomas Braun, Takahiro Ochiya, Masaru Ishii

Nature communications　Vol. 13　No. 1　p. 1066-1066　2022/02/24　Research paper (scientific journal)

Selective targeting of multiple myeloma cells with a monoclonal antibody recognizing the ubiquitous protein CD98 heavy chain.

Kana Hasegawa, Shunya Ikeda, Moto Yaga, Kouki Watanabe, Rika Urakawa, Akie Iehara, Mai Iwai, Seishin Hashiguchi, Soyoko Morimoto, Fumihiro Fujiki, Hiroko Nakajima, Jun Nakata, Sumiyuki Nishida, Akihiro Tsuboi, Yoshihiro Oka, Satoshi Yoshihara, Masahiro Manabe, Hiroyoshi Ichihara, Atsuko Mugitani, Yasutaka Aoyama, Takafumi Nakao, Asao Hirose, Masayuki Hino, Shiho Ueda, Katsuto Takenaka, Takashi Masuko, Koichi Akashi, Takahiro Maruno, Susumu Uchiyama, Shinji Takamatsu, Naoki Wada, Eiichi Morii, Shushi Nagamori, Daisuke Motooka, Yoshikatsu Kanai, Yusuke Oji, Tomoyoshi Nakagawa, Noriyuki Kijima, Haruhiko Kishima, Atsuyo Ikeda, Takayuki Ogino, Yasushi Shintani, Tateki Kubo, Emiko Mihara, Kosuke Yusa, Haruo Sugiyama, Junichi Takagi, Eiji Miyoshi, Atsushi Kumanogoh, Naoki Hosen

Science translational medicine　Vol. 14　No. 632　2022/02/16　Research paper (scientific journal)

CCR8-targeted specific depletion of clonally expanded Treg cells in tumor tissues evokes potent tumor immunity with long-lasting memory.

Yujiro Kidani, Wataru Nogami, Yoshiaki Yasumizu, Atsunari Kawashima, Atsushi Tanaka, Yudai Sonoda, Yumi Tona, Kunitaka Nashiki, Reimi Matsumoto, Masaki Hagiwara, Motonao Osaki, Keiji Dohi, Takayuki Kanazawa, Azumi Ueyama, Mai Yoshikawa, Tetsuya Yoshida, Mitsunobu Matsumoto, Kanji Hojo, Satomi Shinonome, Hiroshi Yoshida, Michinari Hirata, Miya Haruna, Yamami Nakamura, Daisuke Motooka, Daisuke Okuzaki, Yasuko Sugiyama, Makoto Kinoshita, Tatsusada Okuno, Taigo Kato, Koji Hatano, Motohide Uemura, Ryoichi Imamura, Kazunori Yokoi, Atsushi Tanemura, Yasushi Shintani, Tadashi Kimura, Norio Nonomura, Hisashi Wada, Masaki Mori, Yuichiro Doki, Naganari Ohkura, Shimon Sakaguchi

Proceedings of the National Academy of Sciences of the United States of America　Vol. 119　No. 7　2022/02/15　Research paper (scientific journal)

Whole gut virome analysis of 476 Japanese revealed a link between phage and autoimmune disease.

Yoshihiko Tomofuji, Toshihiro Kishikawa, Yuichi Maeda, Kotaro Ogawa, Takuro Nii, Tatsusada Okuno, Eri Oguro-Igashira, Makoto Kinoshita, Kenichi Yamamoto, Kyuto Sonehara, Mayu Yagita, Akiko Hosokawa, Daisuke Motooka, Yuki Matsumoto, Hidetoshi Matsuoka, Maiko Yoshimura, Shiro Ohshima, Shota Nakamura, Hidenori Inohara, Hideki Mochizuki, Kiyoshi Takeda, Atsushi Kumanogoh, Yukinori Okada

Annals of the rheumatic diseases　Vol. 81　No. 2　p. 278-288　2022/02/01　Research paper (scientific journal)

PIK3CA mutation correlates with mTOR pathway expression but not clinical and pathological features in Fibfibroipose vascular anomaly (FAVA).

Yumiko Hori, Katsutoshi Hirose, Michio Ozeki, Kenji Hata, Daisuke Motooka, Shinichiro Tahara, Takahiro Matsui, Masaharu Kohara, Hiroki Higashihara, Yusuke Ono, Kaishu Tanaka, Satoru Toyosawa, Eiichi Morii

Diagnostic pathology　Vol. 17　No. 1　p. 19-19　2022/01/30　Research paper (scientific journal)

A case of massive refractory diarrhea in a patient with <scp>COVID</scp> ‐19

Kentaro Shimizu, Haruhiko Hirata, Natsuko Tokuhira, Akiko Ueda, Daisuke Motooka, Shota Nakamura, Hiroshi Ogura

Acute Medicine &amp; Surgery　Vol. 9　No. 1　2022/01/01　Research paper (scientific journal)

Dynamic change of fecal microbiota and metabolomics in a polymicrobial murine sepsis model

Arisa Muratsu, Mitsunori Ikeda, Kentaro Shimizu, Shoichiro Kameoka, Daisuke Motooka, Shota Nakamura, Hisatake Matsumoto, Hiroshi Ogura, Takeshi Shimazu

ACUTE MEDICINE & SURGERY　Vol. 9　No. 1　2022/01　Research paper (scientific journal)

Enterococcus spp. have higher fitness for survival, in a pH-dependent manner, in pancreatic juice among duodenal bacterial flora.

Saki Itoyama, Emika Noda, Shinji Takamatsu, Jumpei Kondo, Rui Kawaguchi, Munefumi Shimosaka, Tomoya Fukuoka, Daisuke Motooka, Shota Nakamura, Masahiro Tanemura, Suguru Mitsufuji, Yoshifumi Iwagami, Hirofumi Akita, Toru Tobe, Yoshihiro Kamada, Hidetoshi Eguchi, Eiji Miyoshi

JGH open : an open access journal of gastroenterology and hepatology　Vol. 6　No. 1　p. 85-90　2022/01/01　Research paper (scientific journal)

Direct RNA Sequencing Unfolds the Complex Transcriptome of Vibrio parahaemolyticus

Mohamad Al kadi, Eiji Ishii, Dang Tat Truong, Daisuke Motooka, Shigeaki Matsuda, Tetsuya Iida, Toshio Kodama, Daisuke Okuzaki

mSystems　Vol. 6　No. 6　2021/12/21　Research paper (scientific journal)

Identification of conserved SARS-CoV-2 spike epitopes that expand public cTfh clonotypes in mild COVID-19 patients.

Xiuyuan Lu, Yuki Hosono, Masamichi Nagae, Shigenari Ishizuka, Eri Ishikawa, Daisuke Motooka, Yuki Ozaki, Nicolas Sax, Yuichi Maeda, Yasuhiro Kato, Takayoshi Morita, Ryo Shinnakasu, Takeshi Inoue, Taishi Onodera, Takayuki Matsumura, Masaharu Shinkai, Takashi Sato, Shota Nakamura, Shunsuke Mori, Teru Kanda, Emi E Nakayama, Tatsuo Shioda, Tomohiro Kurosaki, Kiyoshi Takeda, Atsushi Kumanogoh, Hisashi Arase, Hironori Nakagami, Kazuo Yamashita, Yoshimasa Takahashi, Sho Yamasaki

The Journal of experimental medicine　Vol. 218　No. 12　2021/12/06　Research paper (scientific journal)

Osteoclasts adapt to physioxia perturbation through DNA demethylation.

Keizo Nishikawa, Shigeto Seno, Toshitada Yoshihara, Ayako Narazaki, Yuki Sugiura, Reito Shimizu, Junichi Kikuta, Reiko Sakaguchi, Norio Suzuki, Norihiko Takeda, Hiroaki Semba, Masamichi Yamamoto, Daisuke Okuzaki, Daisuke Motooka, Yasuhiro Kobayashi, Makoto Suematsu, Haruhiko Koseki, Hideo Matsuda, Masayuki Yamamoto, Seiji Tobita, Yasuo Mori, Masaru Ishii

EMBO reports　Vol. 22　No. 12　2021/12/06　Research paper (scientific journal)

Mitochondrial matrix protein C14orf159 attenuates colorectal cancer metastasis by suppressing Wnt/β-catenin signalling.

Kenji Ohshima, Ryo Oi, Daisuke Okuzaki, Daisuke Motooka, Masakazu Shinohara, Satoshi Nojima, Eiichi Morii

British journal of cancer　Vol. 125　No. 12　p. 1699-1711　2021/12/01　Research paper (scientific journal)

Impact of sleep on the microbiome of oral biofilms.

Maki Sotozono, Nanako Kuriki, Yoko Asahi, Yuichiro Noiri, Mikako Hayashi, Daisuke Motooka, Shota Nakamura, Mikiyo Yamaguchi, Tetsuya Iida, Shigeyuki Ebisu

PloS one　Vol. 16　No. 12　2021/12/01　Research paper (scientific journal)

Chronic pathophysiological changes in the normal brain parenchyma caused by radiotherapy accelerate glioma progression.

Yuichiro Tsuji, Naosuke Nonoguchi, Daisuke Okuzaki, Yusuke Wada, Daisuke Motooka, Yuki Hirota, Taichiro Toho, Nobuhiko Yoshikawa, Motomasa Furuse, Shinji Kawabata, Shin-Ichi Miyatake, Hiroyuki Nakamura, Ryohei Yamamoto, Shota Nakamura, Toshihiko Kuroiwa, Masahiko Wanibuchi

Scientific reports　Vol. 11　No. 1　p. 22110-22110　2021/11/11　Research paper (scientific journal)

High production of egc2-related staphylococcal enterotoxins caused a food poisoning outbreak.

Kaoru Umeda, Hisaya K Ono, Takayuki Wada, Daisuke Motooka, Shota Nakamura, Hiromi Nakamura, Dong-Liang Hu

International journal of food microbiology　Vol. 357　p. 109366-109366　2021/11/02　Research paper (scientific journal)

Aberrant accumulation of TMEM43 accompanied by perturbed transmural gene expression in arrhythmogenic cardiomyopathy.

Haruki Shinomiya, Hisakazu Kato, Yuki Kuramoto, Nozomi Watanabe, Toshihiro Tsuruda, Tadaaki Arimura, Yohei Miyashita, Yoshiki Miyasaka, Tomoji Mashimo, Ayako Takuwa, Daisuke Motooka, Daisuke Okuzaki, Ken Matsuoka, Osamu Tsukamoto, Hideyuki Hakui, Noriaki Yamada, Jong-Kook Lee, Hidetaka Kioka, Masafumi Kitakaze, Seiji Takashima, Yasushi Sakata, Yoshihiro Asano

FASEB journal : official publication of the Federation of American Societies for Experimental Biology　Vol. 35　No. 11　2021/11/01　Research paper (scientific journal)

Vescimonas gen. nov., Vescimonas coprocola sp. nov., Vescimonas fastidiosa sp. nov., Pusillimonas gen. nov. and Pusillimonas faecalis sp. nov. isolated from human faeces.

Maki Kitahara, Yuko Shigeno, Mari Shime, Yuki Matsumoto, Shota Nakamura, Daisuke Motooka, Shota Fukuoka, Hiroyoshi Nishikawa, Yoshimi Benno

International journal of systematic and evolutionary microbiology　Vol. 71　No. 11　2021/11/01　Research paper (scientific journal)

Pleural Effusion Caused by Mycolicibacterium mageritense in an Immunocompetent Host: A Case Report.

Takayuki Niitsu, Tomoki Kuge, Kiyoharu Fukushima, Yuki Matsumoto, Yuko Abe, Masashi Okamoto, Kako Haduki, Haruko Saito, Tadayoshi Nitta, Akira Kawano, Takanori Matsuki, Daisuke Motooka, Kazuyuki Tsujino, Keisuke Miki, Shota Nakamura, Hiroshi Kida, Atsushi Kumanogoh

Frontiers in medicine　Vol. 8　p. 797171-797171　2021/11/01

Repetitive spikes of glucose and lipid induce senescence-like phenotypes of bone marrow stem cells through H3K27me3 demethylase-mediated epigenetic regulation.

Keita Horitani, Masayoshi Iwasaki, Hiroshi Kishimoto, Kensaku Wada, Miyuki Nakano, Haengnam Park, Yasushi Adachi, Daisuke Motooka, Daisuke Okuzaki, Ichiro Shiojima

American journal of physiology. Heart and circulatory physiology　Vol. 321　No. 5　2021/11/01　Research paper (scientific journal)

Analysis of appendectomy samples identified dysbiosis in acute appendicitis

Shinya Munakata, Mari Tohya, Hirokazu Matsuzawa, Yuki Tsuchiya, Kota Amemiya, Toshiaki Hagiwara, Daisuke Motooka, Shota Nakamura, Kazuhiro Sakamoto, Shin Watanabe

Bioscience of Microbiota, Food and Health　Vol. 40　No. 2　p. 92-97　2021/11/01　Research paper (scientific journal)

Comparison of the multigene panel test and OncoScan™ for the determination of HER2 amplification in breast cancer.

Kaori Akazawa, Naofumi Kagara, Yoshiaki Sota, Daisuke Motooka, Shota Nakamura, Tomohiro Miyake, Tomonori Tanei, Yasuto Naoi, Masafumi Shimoda, Seung Jin Kim, Shinzaburo Noguchi, Kenzo Shimazu

Oncology reports　Vol. 46　No. 4　2021/10/01　Research paper (scientific journal)

The ATP-hydrolyzing ectoenzyme E-NTPD8 attenuates colitis through modulation of P2X4 receptor-dependent metabolism in myeloid cells.

Haruka Tani, Bo Li, Takashi Kusu, Ryu Okumura, Junichi Nishimura, Daisuke Okuzaki, Daisuke Motooka, Shoya Arakawa, Asuka Mori, Terukazu Yoshihara, Takayuki Ogino, Shih-Han Tsai, Yoki Furuta, Masato Muneta, Shota Nakamura, Eiichiro Fukusaki, Kimiko Yamamoto, Hideo Yagita, Hisako Kayama, Kiyoshi Takeda

Proceedings of the National Academy of Sciences of the United States of America　Vol. 118　No. 39　2021/09/28　Research paper (scientific journal)

The Firmicutes/Bacteroidetes ratio of the human gut microbiota is associated with prostate enlargement

Kentaro Takezawa, Kazutoshi Fujita, Makoto Matsushita, Daisuke Motooka, Koji Hatano, Eri Banno, Nobutaka Shimizu, Tetsuya Takao, Shingo Takada, Koichi Okada, Shinichiro Fukuhara, Hiroshi Kiuchi, Hirotsugu Uemura, Shota Nakamura, Yoshiyuki Kojima, Norio Nonomura

The Prostate　Vol. 81　No. 16　p. 1287-1293　2021/09/13　Research paper (scientific journal)

Deficiency of the neurodevelopmental disorder-associated gene Cyfip2 alters the retinal ganglion cell properties and visual acuity.

Taro Chaya, Hiroshi Ishikane, Leah R Varner, Yuko Sugita, Yamato Maeda, Ryotaro Tsutsumi, Daisuke Motooka, Daisuke Okuzaki, Takahisa Furukawa

Human molecular genetics　Vol. 31　No. 4　p. 535-547　2021/09/11　Research paper (scientific journal)

Hospital-wide outbreaks of carbapenem-resistant Enterobacteriaceae horizontally spread through a clonal plasmid harbouring blaIMP-1 in children's hospitals in Japan.

Ryuichiro Abe, Fumiya Oyama, Yukihiro Akeda, Masatoshi Nozaki, Takeshi Hatachi, Yuya Okamoto, Hisao Yoshida, Shigeto Hamaguchi, Kazunori Tomono, Yuki Matsumoto, Daisuke Motooka, Tetsuya Iida, Shigeyuki Hamada

The Journal of antimicrobial chemotherapy　Vol. 76　No. 12　p. 3314-3317　2021/09/03　Research paper (scientific journal)

Serum GPL core antibody levels are associated with disease activity and treatment outcomes in Mycobacterium avium complex lung disease following first line antibiotic treatment.

Kiyoharu Fukushima, Seigo Kitada, Yuki Matsumoto, Sho Komukai, Tomoki Kuge, Takahiro Kawasaki, Takanori Matsuki, Daisuke Motooka, Kazuyuki Tsujino, Mari Miki, Keisuke Miki, Shota Nakamura, Hiroshi Kida

Respiratory medicine　Vol. 187　p. 106585-106585　2021/08/26　Research paper (scientific journal)

Metagenome-wide association study revealed disease-specific landscape of the gut microbiome of systemic lupus erythematosus in Japanese.

Yoshihiko Tomofuji, Yuichi Maeda, Eri Oguro-Igashira, Toshihiro Kishikawa, Kenichi Yamamoto, Kyuto Sonehara, Daisuke Motooka, Yuki Matsumoto, Hidetoshi Matsuoka, Maiko Yoshimura, Mayu Yagita, Takuro Nii, Shiro Ohshima, Shota Nakamura, Hidenori Inohara, Kiyoshi Takeda, Atsushi Kumanogoh, Yukinori Okada

Annals of the rheumatic diseases　Vol. 80　No. 12　p. 1575-1583　2021/08/23　Research paper (scientific journal)

Anti-AQP4 autoantibodies promote ATP release from astrocytes and induce mechanical pain in rats.

Teruyuki Ishikura, Makoto Kinoshita, Mikito Shimizu, Yoshiaki Yasumizu, Daisuke Motooka, Daisuke Okuzaki, Kazuya Yamashita, Hisashi Murata, Shohei Beppu, Toru Koda, Satoru Tada, Naoyuki Shiraishi, Yasuko Sugiyama, Katsuichi Miyamoto, Susumu Kusunoki, Tomoyuki Sugimoto, Atsushi Kumanogoh, Tatsusada Okuno, Hideki Mochizuki

Journal of neuroinflammation　Vol. 18　No. 1　p. 181-181　2021/08/21　Research paper (scientific journal)

慢性膵炎を引き起こすEnterococcus faecalisの性状解析

下坂 宗史, 野田 愛美香, 川口 瑠惟, 糸山 幸来, 高松 真二, 元岡 大祐, 中村 昇太, 光藤 傑, 秋田 裕史, 岩上 佳史, 鎌田 佳宏, 江口 英利, 三善 英知

膵臓　Vol. 36　No. 3　p. A330-A330　2021/08

Rapid and simultaneous identification of three mutations by the Novaplex™ SARS-CoV-2 variants I assay kit.

Wakaki Kami, Takeshi Kinjo, Wakako Arakaki, Hiroya Oki, Daisuke Motooka, Shota Nakamura, Jiro Fujita

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology　Vol. 141　p. 104877-104877　2021/08/01　Research paper (scientific journal)

The gut microbiota associated with high-Gleason prostate cancer.

Makoto Matsushita, Kazutoshi Fujita, Daisuke Motooka, Koji Hatano, Shota Fukae, Norihiko Kawamura, Eisuke Tomiyama, Yujiro Hayashi, Eri Banno, Tetsuya Takao, Shingo Takada, Shinichi Yachida, Hirotsugu Uemura, Shota Nakamura, Norio Nonomura

Cancer science　Vol. 112　No. 8　p. 3125-3135　2021/08/01　Research paper (scientific journal)

Gut Microbiota-Derived Short-Chain Fatty Acids Promote Prostate Cancer Growth via IGF1 Signaling.

Makoto Matsushita, Kazutoshi Fujita, Takuji Hayashi, Hisako Kayama, Daisuke Motooka, Hiroaki Hase, Kentaro Jingushi, Gaku Yamamichi, Satoru Yumiba, Eisuke Tomiyama, Yoko Koh, Yujiro Hayashi, Kosuke Nakano, Cong Wang, Yu Ishizuya, Taigo Kato, Koji Hatano, Atsunari Kawashima, Takeshi Ujike, Motohide Uemura, Ryoichi Imamura, Maria D C Rodriguez Pena, Jennifer B Gordetsky, George J Netto, Kazutake Tsujikawa, Shota Nakamura, Kiyoshi Takeda, Norio Nonomura

Cancer research　Vol. 81　No. 15　p. 4014-4026　2021/08/01　Research paper (scientific journal)

Benchmark of 16S rRNA gene amplicon sequencing using Japanese gut microbiome data from the V1-V2 and V3-V4 primer sets.

Shoichiro Kameoka, Daisuke Motooka, Satoshi Watanabe, Ryuichi Kubo, Nicolas Jung, Yuki Midorikawa, Natsuko O Shinozaki, Yu Sawai, Aya K Takeda, Shota Nakamura

BMC genomics　Vol. 22　No. 1　p. 527-527　2021/07/10　Research paper (scientific journal)

DsRNA Sequencing for RNA Virus Surveillance Using Human Clinical Samples.

Takuma Izumi, Yuhei Morioka, Syun-Ichi Urayama, Daisuke Motooka, Tomokazu Tamura, Takahiro Kawagishi, Yuta Kanai, Takeshi Kobayashi, Chikako Ono, Akinari Morinaga, Takahiro Tomiyama, Norifumi Iseda, Yukiko Kosai, Shoichi Inokuchi, Shota Nakamura, Tomohisa Tanaka, Kohji Moriishi, Hiroaki Kariwa, Tomoharu Yoshizumi, Masaki Mori, Yoshiharu Matsuura, Takasuke Fukuhara

Viruses　Vol. 13　No. 7　2021/07/06　Research paper (scientific journal)

Low diversity of gut microbiota in the early phase of post-bone marrow transplantation increases the risk of chronic graft-versus-host disease

Tatsuya Konishi, Shinsuke Kusakabe, Akihisa Hino, Kyoko Inamoto, Kota Yoshifuji, Yuko Kiridoshi, Kozue Takeshita, Satoshi Sasajima, Takashi Toya, Aiko Igarashi, Yuho Najima, Takeshi Kobayashi, Noriko Doki, Daisuke Motooka, Shota Nakamura, Masahiro Suyama, Wataru Suda, Atsushi Shiota, Koji Atarashi, Masahira Hattori, Kenya Honda, Takafumi Yokota, Kazuteru Ohashi, Hirohiko Shibayama, Kentaro Fukushima, Kazuhiko Kakihana

Bone Marrow Transplantation　Vol. 56　No. 7　p. 1728-1731　2021/07　Research paper (scientific journal)

Alleviation of colonic inflammation by Lypd8 in a mouse model of inflammatory bowel disease

Chiao Ching Hsu, Ryu Okumura, Daisuke Motooka, Reo Sasaki, Shota Nakamura, Tetsuya Iida, Kiyoshi Takeda

International Immunology　Vol. 33　No. 7　p. 359-372　2021/07/01　Research paper (scientific journal)

Low diversity of gut microbiota in the early phase of post-bone marrow transplantation increases the risk of chronic graft-versus-host disease

Tatsuya Konishi, Shinsuke Kusakabe, Akihisa Hino, Kyoko Inamoto, Kota Yoshifuji, Yuko Kiridoshi, Kozue Takeshita, Satoshi Sasajima, Takashi Toya, Aiko Igarashi, Yuho Najima, Takeshi Kobayashi, Noriko Doki, Daisuke Motooka, Shota Nakamura, Masahiro Suyama, Wataru Suda, Atsushi Shiota, Koji Atarashi, Masahira Hattori, Kenya Honda, Takafumi Yokota, Kazuteru Ohashi, Hirohiko Shibayama, Kentaro Fukushima, Kazuhiko Kakihana

Bone Marrow Transplantation　Vol. 56　No. 7　p. 1728-1731　2021/07/01　Research paper (scientific journal)

Enhanced Carbapenem Resistance through Multimerization of Plasmids Carrying Carbapenemase Genes.

Ryuichiro Abe, Yukihiro Akeda, Yo Sugawara, Yuki Matsumoto, Daisuke Motooka, Ryuji Kawahara, Norihisa Yamamoto, Kazunori Tomono, Tetsuya Iida, Shigeyuki Hamada

mBio　Vol. 12　No. 3　2021/06/29　Research paper (scientific journal)

Engineered ACE2 receptor therapy overcomes mutational escape of SARS-CoV-2.

Yusuke Higuchi, Tatsuya Suzuki, Takao Arimori, Nariko Ikemura, Emiko Mihara, Yuhei Kirita, Eriko Ohgitani, Osam Mazda, Daisuke Motooka, Shota Nakamura, Yusuke Sakai, Yumi Itoh, Fuminori Sugihara, Yoshiharu Matsuura, Satoaki Matoba, Toru Okamoto, Junichi Takagi, Atsushi Hoshino

Nature communications　Vol. 12　No. 1　p. 3802-3802　2021/06/21　Research paper (scientific journal)

Transcriptomics Identify Thrombospondin-2 as a Biomarker for NASH and Advanced Liver Fibrosis.

Kazuhiro Kozumi, Takahiro Kodama, Hiroki Murai, Sadatsugu Sakane, Olivier Govaere, Simon Cockell, Daisuke Motooka, Naruyasu Kakita, Yukinori Yamada, Yasuteru Kondo, Yuki Tahata, Ryoko Yamada, Hayato Hikita, Ryotaro Sakamori, Yoshihiro Kamada, Ann K Daly, Quentin M Anstee, Tomohide Tatsumi, Eiichi Morii, Tetsuo Takehara

Hepatology (Baltimore, Md.)　Vol. 74　No. 5　p. 2452-2466　2021/06/09　Research paper (scientific journal)

Community spread and acquisition of clinically relevant Escherichia coli harbouring bla<inf>NDM</inf>among healthy Japanese residents of Yangon, Myanmar

Yo Sugawara, Hideharu Hagiya, Yukihiro Akeda, Dan Takeuchi, Noriko Sakamoto, Yuki Matsumoto, Daisuke Motooka, Isao Nishi, Kazunori Tomono, Shigeyuki Hamada

Journal of Antimicrobial Chemotherapy　Vol. 76　No. 6　p. 1448-1454　2021/06/01　Research paper (scientific journal)

Importance of lymph node immune responses in MSI-H/dMMR colorectal cancer

Koji Inamori, Yosuke Togashi, Shota Fukuoka, Kiwamu Akagi, Kouetsu Ogasawara, Takuma Irie, Daisuke Motooka, Yoichi Kobayashi, Daisuke Sugiyama, Motohiro Kojima, Norihiko Shiiya, Shota Nakamura, Shoichi Maruyama, Yutaka Suzuki, Masaaki Ito, Hiroyoshi Nishikawa

JCI Insight　Vol. 6　No. 9　2021/05/10　Research paper (scientific journal)

Cyclosporine A Treatment of Proteinuria in a New Case of MAFB-Associated Glomerulopathy without Extrarenal Involvement: A Case Report.

Jun-Ya Kaimori, Tatsuhiko Mori, Tomoko Namba-Hamano, Takeshi Morimoto, Ayako Takuwa, Daisuke Motooka, Atsuko Okazaki, Kaori Kobayashi, Yuta Asahina, Sachio Kajimoto, Yohei Doi, Tatsufumi Oka, Yusuke Sakaguchi, Akihiro Nakaya, Yoshitaka Isaka

Nephron　Vol. 145　No. 4　p. 445-450　2021/05/01

Characterization of bla NDM-5-harbouring Klebsiella pneumoniae sequence type 11 international high-risk clones isolated from clinical samples in Yangon General Hospital, a tertiary-care hospital in Myanmar.

Yo Sugawara, Yukihiro Akeda, Hideharu Hagiya, Khwar Nyo Zin, Mya Mya Aye, Dan Takeuchi, Yuki Matsumoto, Daisuke Motooka, Isao Nishi, Kazunori Tomono, Shigeyuki Hamada

Journal of medical microbiology　Vol. 70　No. 5　2021/05/01　Research paper (scientific journal)

Comparative evaluation of microbial profiles of oral samples obtained at different collection time points and using different methods

Michi Omori, Nahoko Kato-Kogoe, Shoichi Sakaguchi, Nozomu Fukui, Kayoko Yamamoto, Yoichiro Nakajima, Kazuya Inoue, Hiroyuki Nakano, Daisuke Motooka, Takashi Nakano, Shota Nakamura, Takaaki Ueno

Clinical Oral Investigations　Vol. 25　No. 5　p. 2779-2789　2021/05/01　Research paper (scientific journal)

次世代シーケンサーを用いた病原性非結核性抗酸菌の多様性の解明

福島 清春, 松本 悠希, 久下 朋輝, 松木 隆典, 香川 浩之, 元岡 大祐, 辻野 和之, 三木 真理, 三木 啓資, 中村 昇太, 北田 清悟, 木田 博

日本呼吸器学会誌　Vol. 10　No. 増刊　p. 219-219　2021/04

次世代シーケンサーを用いた病原性非結核性抗酸菌の多様性の解明

福島 清春, 松本 悠希, 久下 朋輝, 松木 隆典, 香川 浩之, 元岡 大祐, 辻野 和之, 三木 真理, 三木 啓資, 中村 昇太, 北田 清悟, 木田 博

日本呼吸器学会誌　Vol. 10　No. 増刊　p. 219-219　2021/04

Streptococcus pyogenes upregulates arginine catabolism to exert its pathogenesis on the skin surface

Yujiro Hirose, Masaya Yamaguchi, Tomoko Sumitomo, Masanobu Nakata, Tomoki Hanada, Daisuke Okuzaki, Daisuke Motooka, Yasushi Mori, Hiroshi Kawasaki, Alison Coady, Satoshi Uchiyama, Masanobu Hiraoka, Raymond H. Zurich, Masayuki Amagai, Victor Nizet, Shigetada Kawabata

Cell Reports　Vol. 34　No. 13　2021/03/30　Research paper (scientific journal)

空間的トランスクリプトーム解析を用いた皮膚創部の微小環境における細胞間相互作用解明の試み

森 亮一, 金 湘殷, 亀岡 章一郎, 元岡 大祐, 奥崎 大介, 林 洋子, 下川 功

日本病理学会会誌　Vol. 110　No. 1　p. 227-227　2021/03

空間的トランスクリプトーム解析を用いた皮膚創部の微小環境における細胞間相互作用解明の試み

森 亮一, 金 湘殷, 亀岡 章一郎, 元岡 大祐, 奥崎 大介, 林 洋子, 下川 功

日本病理学会会誌　Vol. 110　No. 1　p. 227-227　2021/03

Gut Dysbiosis Associated with Antibiotics and Disease Severity and Its Relation to Mortality in Critically Ill Patients

Masahiro Ojima, Kentaro Shimizu, Daisuke Motooka, Takuma Ishihara, Shota Nakamura, Ayumi Shintani, Hiroshi Ogura, Tetsuya Iida, Kazuhisa Yoshiya, Takeshi Shimazu

Digestive Diseases and Sciences　Vol. 67　No. 6　p. 2420-2432　2021/03/01　Research paper (scientific journal)

Genomic characterization of clinical Enterobacter roggenkampii co-harbouring bla<inf>IMP-1</inf>- and bla<inf>GES-5</inf>-encoding IncP6 and mcr-9-encoding IncHI2 plasmids isolated in Japan

Kaoru Umeda, Hiromi Nakamura, Akira Fukuda, Yuki Matsumoto, Daisuke Motooka, Shota Nakamura, Yoshinori Yasui, Hideki Yoshida, Ryuji Kawahara

Journal of Global Antimicrobial Resistance　Vol. 24　p. 220-227　2021/03/01　Research paper (scientific journal)

Group 2 innate lymphoid cells support hematopoietic recovery under stress conditions

Takao Sudo, Yasutaka Motomura, Daisuke Okuzaki, Tetsuo Hasegawa, Takafumi Yokota, Junichi Kikuta, Tomoka Ao, Hiroki Mizuno, Takahiro Matsui, Daisuke Motooka, Ryosuke Yoshizawa, Takashi Nagasawa, Yuzuru Kanakura, Kazuyo Moro, Masaru Ishii

Journal of Experimental Medicine　Vol. 218　No. 5　2021/03/01　Research paper (scientific journal)

ST6GAL1 Is a Novel Serum Biomarker for Lenvatinib-Susceptible FGF19-Driven Hepatocellular Carcinoma

Yuta Myojin, Takahiro Kodama, Kazuki Maesaka, Daisuke Motooka, Yu Sato, Satoshi Tanaka, Yuichi Abe, Kazuyoshi Ohkawa, Eiji Mita, Yoshito Hayashi, Hayato Hikita, Ryotaro Sakamori, Tomohide Tatsumi, Ayumu Taguchi, Hidetoshi Eguchi, Tetsuo Takehara

Clinical Cancer Research　Vol. 27　No. 4　p. 1150-1161　2021/02/15　Research paper (scientific journal)

Epidemiological analysis of pneumococcal strains isolated at yangon children’s hospital in Myanmar via whole-genome sequencing-based methods

Masaya Yamaguchi, Hpoo Pwint Myo Win, Kotaro Higashi, Masayuki Ono, Yujiro Hirose, Daisuke Motooka, Daisuke Okuzaki, Mya Mya Aye, Moh Moh Htun, Hlaing Myat Thu, Shigetada Kawabata

Microbial Genomics　Vol. 7　No. 2　p. 1-14　2021/02/01　Research paper (scientific journal)

Whole-genome analyses of extended-spectrum or AmpC β-lactamase-producing Escherichia coli isolates from companion dogs in Japan

Mayo Yasugi, Shingo Hatoya, Daisuke Motooka, Yuki Matsumoto, Shunsuke Shimamura, Hiroyuki Tani, Masaru Furuya, Keiichiro Mie, Masami Miyake, Shota Nakamura, Terumasa Shimada

PLoS ONE　Vol. 16　No. 2-Feb　2021/02/01　Research paper (scientific journal)

Oral intake of silica nanoparticles exacerbates intestinal inflammation

Takao Ogawa, Ryu Okumura, Kazuya Nagano, Tomomi Minemura, Masahiro Izumi, Daisuke Motooka, Shota Nakamura, Tetsuya Iida, Yuichi Maeda, Atsushi Kumanogoh, Yasuo Tsutsumi, Kiyoshi Takeda

Biochemical and Biophysical Research Communications　Vol. 534　p. 540-546　2021/01/01　Research paper (scientific journal)

Genomic features of plasmids coding for KPC-2, NDM-5 or OXA-48 carbapenemases in Enterobacteriaceae from Malawi

Geoffrey Peterkins Kumwenda, Yo Sugawara, Yukihiro Akeda, Yuki Matsumoto, Daisuke Motooka, Kazunori Tomono, Shigeyuki Hamada

Journal of Antimicrobial Chemotherapy　Vol. 76　No. 1　p. 267-270　2021/01/01

Impacts of sleep on the characteristics of dental biofilm

Maki Sotozono, Nanako Kuriki, Yoko Asahi, Yuichiro Noiri, Mikako Hayashi, Daisuke Motooka, Shota Nakamura, Hiroyuki Machi, Tetsuya Iida, Shigeyuki Ebisu

Scientific Reports　Vol. 11　No. 1　2021/01/01　Research paper (scientific journal)

Ectonucleotidase CD39 is highly expressed on ATLL cells and is responsible for their immunosuppressive function

Yasuhiro Nagate, Sachiko Ezoe, Jiro Fujita, Daisuke Okuzaki, Daisuke Motooka, Tomohiko Ishibashi, Michiko Ichii, Akira Tanimura, Masako Kurashige, Eiichi Morii, Takuya Fukushima, Youko Suehiro, Takafumi Yokota, Hirohiko Shibayama, Kenji Oritani, Yuzuru Kanakura

Leukemia　Vol. 35　No. 1　p. 107-118　2021/01　Research paper (scientific journal)

A Metagenome-Wide Association Study of Gut Microbiome in Patients With Multiple Sclerosis Revealed Novel Disease Pathology

Toshihiro Kishikawa, Kotaro Ogawa, Daisuke Motooka, Akiko Hosokawa, Makoto Kinoshita, Ken Suzuki, Kenichi Yamamoto, Tatsuo Masuda, Yuki Matsumoto, Takuro Nii, Yuichi Maeda, Shota Nakamura, Hidenori Inohara, Hideki Mochizuki, Tatsusada Okuno, Yukinori Okada

Frontiers in Cellular and Infection Microbiology　Vol. 10　2020/12/11　Research paper (scientific journal)

Pulmonary disease caused by a newly identified mycobacterium: Mycolicibacterium toneyamachuris: a case report

Tomoki Kuge, Kiyoharu Fukushima, Yuki Matsumoto, Yuko Abe, Eri Akiba, Kako Haduki, Haruko Saito, Tadayoshi Nitta, Akira Kawano, Takahiro Kawasaki, Takanori Matsuki, Hiroyuki Kagawa, Daisuke Motooka, Kazuyuki Tsujino, Mari Miki, Keisuke Miki, Seigo Kitada, Shota Nakamura, Tetsuya Iida, Hiroshi Kida

BMC Infectious Diseases　Vol. 20　No. 1　2020/12/01　Research paper (scientific journal)

Detection of Genetic Elements Carrying vanA in Vancomycin-Resistant Enterococcus saigonensis VE80^TIsolated from Retail Chicken Meat

Tetsuya Harada, Daisuke Motooka, Shota Nakamura, Yoshimasa Yamamoto, Takahiro Yamaguchi, Ryuji Kawahara, Kentaro Kawatsu

Foodborne Pathogens and Disease　Vol. 17　No. 12　p. 772-774　2020/12/01　Research paper (scientific journal)

Adeno-associated virus-mediated gene delivery promotes S-phase entry-independent precise targeted integration in cardiomyocytes

Yasuaki Kohama, Shuichiro Higo, Yuki Masumura, Mikio Shiba, Takumi Kondo, Takamaru Ishizu, Tomoaki Higo, Satoki Nakamura, Satoshi Kameda, Tomoka Tabata, Hiroyuki Inoue, Daisuke Motooka, Daisuke Okuzaki, Seiji Takashima, Shigeru Miyagawa, Yoshiki Sawa, Shungo Hikoso, Yasushi Sakata

Scientific Reports　Vol. 10　No. 1　2020/12/01　Research paper (scientific journal)

Novel human reovirus isolated from children and its long-term circulation with reassortments

Seiji P. Yamamoto, Daisuke Motooka, Kazutaka Egawa, Atsushi Kaida, Yuki Hirai, Hideyuki Kubo, Kazushi Motomura, Shota Nakamura, Nobuhiro Iritani

Scientific Reports　Vol. 10　No. 1　2020/12/01　Research paper (scientific journal)

Improvement of CRISPR/Cas9 system by transfecting Cas9-expressing Plasmodium berghei with linear donor template

Naoaki Shinzawa, Tsubasa Nishi, Fumiya Hiyoshi, Daisuke Motooka, Masao Yuda, Shiroh Iwanaga

Communications Biology　Vol. 3　No. 1　2020/12/01　Research paper (scientific journal)

Characterization of the Plasmidome Encoding Carbapenemase and Mechanisms for Dissemination of Carbapenem-Resistant Enterobacteriaceae

Ryuichiro Abe, Yukihiro Akeda, Yo Sugawara, Dan Takeuchi, Yuki Matsumoto, Daisuke Motooka, Norihisa Yamamoto, Ryuji Kawahara, Kazunori Tomono, Yuji Fujino, Shigeyuki Hamada

mSystems　Vol. 5　No. 6　2020/11/10　Research paper (scientific journal)

HTR3A is correlated with unfavorable histology and promotes proliferation through ERK phosphorylation in lung adenocarcinoma

Mitsuyo Tone, Shinichiro Tahara, Satoshi Nojima, Daisuke Motooka, Daisuke Okuzaki, Eiichi Morii

Cancer Science　Vol. 111　No. 10　p. 3953-3961　2020/10/01　Research paper (scientific journal)

Fecal Gram staining of phagocytosed bacteria to differentiate methicillin-resistant Staphylococcus aureus: A case report

Kentaro Shimizu, Ayumi Takahashi, Daisuke Motooka, Shota Nakamura, Kazunori Tomono, Hiroshi Ogura, Takeshi Shimazu

Journal of Infection and Chemotherapy　Vol. 26　No. 10　p. 1078-1081　2020/10　Research paper (scientific journal)

High affinity modified ACE2 receptors prevent SARS-CoV-2 infection

Yusuke Higuchi, Tatsuya Suzuki, Takao Arimori, Nariko Ikemura, Yuhei Kirita, Eriko Ohgitani, Osam Mazda, Daisuke Motooka, Shota Nakamura, Yoshiharu Matsuura, Satoaki Matoba, Toru Okamoto, Junichi Takagi, Atsushi Hoshino

2020/09/16

Signal-transducing adapter protein-1 is required for maintenance of leukemic stem cells in CML

Jun Toda, Michiko Ichii, Kenji Oritani, Hirohiko Shibayama, Akira Tanimura, Hideaki Saito, Takafumi Yokota, Daisuke Motooka, Daisuke Okuzaki, Yuichi Kitai, Ryuta Muromoto, Jun ichi Kashiwakura, Tadashi Matsuda, Naoki Hosen, Yuzuru Kanakura

Oncogene　Vol. 39　No. 34　p. 5601-5615　2020/08/20　Research paper (scientific journal)

Detection of ctDNA with Personalized Molecular Barcode NGS and Its Clinical Significance in Patients with Early Breast Cancer

Tetsuhiro Yoshinami, Naofumi Kagara, Daisuke Motooka, Shota Nakamura, Tomohiro Miyake, Tomonori Tanei, Yasuto Naoi, Masafumi Shimoda, Kenzo Shimazu, Seung Jin Kim, Shinzaburo Noguchi

Translational Oncology　Vol. 13　No. 8　2020/08/01　Research paper (scientific journal)

Migration arrest of chemoresistant leukemia cells mediated by MRTF-SRF pathway

Maho Morimatsu, Erika Yamashita, Shigeto Seno, Takao Sudo, Junichi Kikuta, Hiroki Mizuno, Daisuke Okuzaki, Daisuke Motooka, Masaru Ishii

Inflammation and Regeneration　Vol. 40　No. 1　p. 15-15　2020/07/06　Research paper (scientific journal)

High-Performance Virus Detection System by using Deep Learning

Ying Feng Hsu, Makiko Ito, Takumi Maruyama, Morito Matsuoka, Nicolas Jung, Yuki Matsumoto, Daisuke Motooka, Shota Nakamura

2020 IEEE Congress on Evolutionary Computation, CEC 2020 - Conference Proceedings　2020/07/01　Research paper (international conference proceedings)

Emergence and diversification of a host-parasite RNA ecosystem through Darwinian evolution

Taro Furubayashi, Kensuke Ueda, Yohsuke Bansho, Daisuke Motooka, Shota Nakamura, Ryo Mizuuchi, Norikazu Ichihashi

eLife　Vol. 9　p. 1-15　2020/07　Research paper (scientific journal)

UNAGI: an automated pipeline for nanopore full-length cDNA sequencing uncovers novel transcripts and isoforms in yeast

Mohamad Al kadi, Nicolas Jung, Shingo Ito, Shoichiro Kameoka, Takashi Hishida, Daisuke Motooka, Shota Nakamura, Tetsuya Iida, Daisuke Okuzaki

Functional and Integrative Genomics　Vol. 20　No. 4　p. 523-536　2020/07/01　Research paper (scientific journal)

Regulatory T Cell-Specific Epigenomic Region Variants Are a Key Determinant of Susceptibility to Common Autoimmune Diseases

Naganari Ohkura, Yoshiaki Yasumizu, Yohko Kitagawa, Atsushi Tanaka, Yamami Nakamura, Daisuke Motooka, Shota Nakamura, Yukinori Okada, Shimon Sakaguchi

Immunity　Vol. 52　No. 6　p. 1119-1132.e4　2020/06/16　Research paper (scientific journal)

The impact of adjuvant surgical treatment of nontuberculous mycobacterial pulmonary disease on prognosis and outcome

Kiyoharu Fukushima, Kiyoharu Fukushima, Mari Miki, Yuki Matsumoto, Emi Uda, Yuji Yamamoto, Yuya Kogita, Yuko Kagawa, Takanori Matsuki, Hiroyuki Kagawa, Yohei Oshitani, Daisuke Motooka, Kazuyuki Tsujino, Kenji Yoshimura, Keisuke Miki, Akio Hayashi, Shota Nakamura, Seigo Kitada, Yukiyasu Takeuchi, Hiroshi Kida

Respiratory Research　Vol. 21　No. 1　p. 153-153　2020/06/16　Research paper (scientific journal)

Host immune response and novel diagnostic approach to NTM infections

Yuko Abe, Kiyoharu Fukushima, Yuki Hosono, Yuki Matsumoto, Daisuke Motooka, Naoko Ose, Shota Nakamura, Seigo Kitada, Hiroshi Kida, Atsushi Kumanogoh

International Journal of Molecular Sciences　Vol. 21　No. 12　p. 1-15　2020/06/02

Skin mycobiome of psoriasis patients is retained during treatment with TNF and IL-17 inhibitors

Yuta Koike, Sayaka Kuwatsuka, Katsutaro Nishimoto, Daisuke Motooka, Hiroyuki Murota

International Journal of Molecular Sciences　Vol. 21　No. 11　p. 1-9　2020/06/01　Research paper (scientific journal)

Whole-genome sequencing and comparative analysis of the genomes of Bacteroides thetaiotaomicron and Escherichia coli isolated from a healthy resident in Vietnam

Mashkoor Mohsin, Kaori Tanaka, Ryuji Kawahara, Shinji Kondo, Hideki Noguchi, Daisuke Motooka, Shota Nakamura, Diep Thi Khong, Thang Nam Nguyen, Trong Nang Hoang, Yoshimasa Yamamoto

Journal of Global Antimicrobial Resistance　Vol. 21　p. 65-67　2020/06

Generation of human bronchial organoids for SARS-CoV-2 research

Tatsuya Suzuki, Yumi Itoh, Yusuke Sakai, Akatsuki Saito, Daisuke Okuzaki, Daisuke Motooka, Shohei Minami, Takeshi Kobayashi, Takuya Yamamoto, Toru Okamoto, Kazuo Takayama

2020/05/26

Long non-coding RNA MANCR is a target of BET bromodomain protein BRD4 and plays a critical role in cellular migration and invasion abilities of prostate cancer

Masayuki Nagasawa, Kosuke Tomimatsu, Koji Terada, Kenta Kondo, Kazuko Miyazaki, Masaki Miyazaki, Daisuke Motooka, Daisuke Okuzaki, Tetsuya Yoshida, Susumu Kageyama, Hiroshi Kawamoto, Akihiro Kawauchi, Yasutoshi Agata

Biochemical and Biophysical Research Communications　Vol. 526　No. 1　p. 128-134　2020/05/21　Research paper (scientific journal)

Enterococcus: A Predictor of Ravaged Microbiota and Poor Prognosis after Allogeneic Hematopoietic Stem Cell Transplantation

Shinsuke Kusakabe, Kentaro Fukushima, Takafumi Yokota, Akihisa Hino, Jiro Fujita, Daisuke Motooka, Shota Nakamura, Hirohiko Shibayama, Yuzuru Kanakura

Biology of Blood and Marrow Transplantation　Vol. 26　No. 5　p. 1028-1033　2020/05　Research paper (scientific journal)

Dysregulated Expression of the Nuclear Exosome Targeting Complex Component Rbm7 in Nonhematopoietic Cells Licenses the Development of Fibrosis

Kiyoharu Fukushima, Takashi Satoh, Fuminori Sugihara, Yuki Sato, Toru Okamoto, Yuichi Mitsui, Sachiyo Yoshio, Songling Li, Satoshi Nojima, Daisuke Motooka, Shota Nakamura, Hiroshi Kida, Daron M. Standley, Eiichi Morii, Tatsuya Kanto, Motoko Yanagita, Yoshiharu Matsuura, Takashi Nagasawa, Atsushi Kumanogoh, Shizuo Akira

Immunity　Vol. 52　No. 3　p. 542-556.e13　2020/03/17　Research paper (scientific journal)

Metagenomic profiling of potential pathogens isolated from blood samples and tracheal aspirates of critically ill children with persistent fever unresponsive to broad-spectrum antibiotics

Warunee Punpanich Vandepitte, Rungrat Sukharom, Nuanjun Wichukchinda, Kunihiro Kaihatsu, Daisuke Motooka, Shota Nakamura

Southeast Asian Journal of Tropical Medicine and Public Health　Vol. 51　No. 2　p. 236-250　2020/03/01　Research paper (scientific journal)

A lassa virus live-attenuated vaccine candidate based on rearrangement of the intergenic region

Yingyun Cai, Masaharu Iwasaki, Daisuke Motooka, David X. Liu, Shuiqing Yu, Kurt Cooper, Randy Hart, Ricky Adams, Tracey Burdette, Elena N. Postnikova, Jonathan Kurtz, Marisa St Claire, Chengjin Ye, Jens H. Kuhn, Luis Martínez-Sobrido, Juan Carlos De La Torre

mBio　Vol. 11　No. 2　2020/03/01　Research paper (scientific journal)

Molecular Barcode Sequencing of the Whole Ligand Binding Domain of the ESR1 Gene in Cell-Free DNA from Patients with Metastatic Breast Cancer

Nanae Masunaga, Naofumi Kagara, Daisuke Motooka, Shota Nakamura, Tomohiro Miyake, Tomonori Tanei, Yasuto Naoi, Masafumi Shimoda, Kenzo Shimazu, Seung Jin Kim, Shinzaburo Noguchi

Translational Oncology　Vol. 13　No. 3　p. 100735-100735　2020/03　Research paper (scientific journal)

High prevalence of colistin-resistant escherichia coli with chromosomally carried mcr-1 in healthy residents in Vietnam

Takahiro Yamaguchi, Ryuji Kawahara, Kouta Hamamoto, Itaru Hirai, Diep Thi Khong, Thang Nam Nguyen, Hoa Thi Tran, Daisuke Motooka, Shota Nakamura, Yoshimasa Yamamoto

mSphere　Vol. 5　No. 2　2020/03/01　Research paper (scientific journal)

Bordetella dermonecrotic toxin is a neurotropic virulence factor that uses Ca<inf>v</inf>3.1 as the cell surface receptor

Shihono Teruya, Yukihiro Hiramatsu, Keiji Nakamura, Aya Fukui-Miyazaki, Kentaro Tsukamoto, Noriko Shinoda, Daisuke Motooka, Shota Nakamura, Keisuke Ishigaki, Naoaki Shinzawa, Takashi Nishida, Fuminori Sugihara, Yusuke Maeda, Yasuhiko Horiguchi

mBio　Vol. 11　No. 2　p. e03146-19　2020/03　Research paper (scientific journal)

The autophagy-related protein GABARAP is induced during overwintering in the bean bug (Hemiptera: Alydidae)

Shin Ichiro Tachibana, Shinji Matsuzaki, Masako Tanaka, Masayuki Shiota, Daisuke Motooka, Shota Nakamura, Shin G. Goto

Journal of Economic Entomology　Vol. 113　No. 1　p. 427-434　2020/02/08　Research paper (scientific journal)

Phosphorothioation of foreign DNA influences the transformation efficiency in Clostridium perfringens NCTC8239

Mayo Yasugi, Daisuke Motooka, Shota Nakamura, Masami Miyake

Anaerobe　Vol. 61　2020/02　Research paper (scientific journal)

Pre- and post-serial metagenomic analysis of gut microbiota as a prognostic factor in patients undergoing haematopoietic stem cell transplantation

Shinsuke Kusakabe, Kentaro Fukushima, Tetsuo Maeda, Daisuke Motooka, Shota Nakamura, Jiro Fujita, Takafumi Yokota, Hirohiko Shibayama, Kenji Oritani, Yuzuru Kanakura

British Journal of Haematology　Vol. 188　No. 3　p. 438-449　2020/02/01　Research paper (scientific journal)

Signal-transducing adaptor protein-2 delays recovery of B lineage lymphocytes during hematopoietic stress

Michiko Ichii, Kenji Oritani, Jun Toda, Hideaki Saito, Henyun Shi, Hirohiko Shibayama, Daisuke Motooka, Yuichi Kitai, Ryuta Muromoto, Jun Ichi Kashiwakura, Kodai Saitoh, Daisuke Okuzaki, Tadashi Matsuda, Yuzuru Kanakura

Haematologica　Vol. 105　No. 5　2020/01/01　Research paper (scientific journal)

Metagenome-wide association study of gut microbiome revealed novel aetiology of rheumatoid arthritis in the Japanese population

Toshihiro Kishikawa, Yuichi Maeda, Takuro Nii, Daisuke Motooka, Yuki Matsumoto, Masato Matsushita, Hidetoshi Matsuoka, Maiko Yoshimura, Shoji Kawada, Satoru Teshigawara, Eri Oguro, Yasutaka Okita, Keisuke Kawamoto, Shinji Higa, Toru Hirano, Masashi Narazaki, Atsushi Ogata, Yukihiko Saeki, Shota Nakamura, Hidenori Inohara, Atsushi Kumanogoh, Kiyoshi Takeda, Yukinori Okada

Annals of the Rheumatic Diseases　Vol. 79　No. 1　p. 103-111　2020/01/01　Research paper (scientific journal)

Molecular characterization of bla<inf>KHM-1</inf> encoding plasmid in an Enterobacter hormaechei subsp. Hoffmannii isolate from blood culture

Kaoru Umeda, Hiromi Nakamura, Akira Fukuda, Takahiro Yamaguchi, Yuki Matsumoto, Daisuke Motooka, Shota Nakamura, Ryuji Kawahara

PLoS ONE　Vol. 15　No. 1　2020/01　Research paper (scientific journal)

Target enrichment from a DNA mixture by oligoribonucleotide interference-PCR (ORNi-PCR)

Toshitsugu Fujita, Daisuke Motooka, Hodaka Fujii

Biology Methods and Protocols　Vol. 4　No. 1　2019/12/27　Research paper (scientific journal)

Conjunctival dysbiosis in mucosa-associated lymphoid tissue lymphoma

Kazunobu Asao, Noriyasu Hashida, Satoru Ando, Daisuke Motooka, Hiroyuki Kurakami, Shota Nakamura, Daisuke Yamashita, Kazuichi Maruyama, Satoshi Kawasaki, Tomomi Yamada, Tetsuya Iida, Kohji Nishida

Scientific Reports　Vol. 9　No. 1　p. 8424-8424　2019/12/01　Research paper (scientific journal)

Comparison of Japanese and Indian intestinal microbiota shows diet-dependent interaction between bacteria and fungi

Siddhika Pareek, Takashi Kurakawa, Bhabatosh Das, Daisuke Motooka, Shuuichi Nakaya, Temsunaro Rongsen-Chandola, Nidhi Goyal, Hisako Kayama, Dylan Dodd, Ryu Okumura, Yuichi Maeda, Kosuke Fujimoto, Takuro Nii, Takao Ogawa, Tetsuya Iida, Nita Bhandari, Toshiyuki Kida, Shota Nakamura, G. Balakrish Nair, Kiyoshi Takeda

npj Biofilms and Microbiomes　Vol. 5　No. 1　2019/12/01　Research paper (scientific journal)

Distinct methylation levels of mature microRNAs in gastrointestinal cancers

Masamitsu Konno, Jun Koseki, Ayumu Asai, Akira Yamagata, Teppei Shimamura, Daisuke Motooka, Daisuke Okuzaki, Koichi Kawamoto, Tsunekazu Mizushima, Hidetoshi Eguchi, Shuji Takiguchi, Taroh Satoh, Koshi Mimori, Takahiro Ochiya, Yuichiro Doki, Ken Ofusa, Masaki Mori, Hideshi Ishii

Nature Communications　Vol. 10　No. 1　p. 3888-3888　2019/12/01　Research paper (scientific journal)

Specific increase of Fusobacterium in the faecal microbiota of neonatal calves infected with Cryptosporidium parvum

Madoka Ichikawa-Seki, Daisuke Motooka, Aiko Kinami, Fumi Murakoshi, Yoko Takahashi, Junya Aita, Kei Hayashi, Atsushi Tashibu, Shota Nakamura, Tetsuya Iida, Toshihiro Horii, Yoshifumi Nishikawa

Scientific Reports　Vol. 9　No. 1　2019/12/01　Research paper (scientific journal)

Characterization of human pegivirus infection in liver transplantation recipients

Takuma Izumi, Kazuhito Sakata, Daisuke Okuzaki, Shoichi Inokuchi, Tomokazu Tamura, Daisuke Motooka, Shota Nakamura, Chikako Ono, Masahiro Shimokawa, Yoshiharu Matsuura, Masaki Mori, Takasuke Fukuhara, Tomoharu Yoshizumi

Journal of Medical Virology　Vol. 91　No. 12　p. 2093-2100　2019/12/01　Research paper (scientific journal)

Streptococcus pyogenes transcriptome changes in the inflammatory environment of necrotizing fasciitis

Yujiro Hirose, Masaya Yamaguchi, Daisuke Okuzaki, Daisuke Motooka, Hiroshi Hamamoto, Tomoki Hanada, Tomoko Sumitomo, Masanobu Nakata, Shigetada Kawabata

Applied and Environmental Microbiology　Vol. 85　No. 21　2019/11/01　Research paper (scientific journal)

Expression of polydom in dermal neurofibroma and surrounding dermis in von Recklinghausen's disease

Tomo Kamitani, Hiroyuki Murota, Noriko Arase, Mari Wataya-Kaneda, Ryoko Sato-Nishiuchi, Kiyotoshi Sekiguchi, Daisuke Okuzaki, Daisuke Motooka, Ichiro Katayama

Journal of Dermatological Science　Vol. 96　No. 2　p. 73-80　2019/11　Research paper (scientific journal)

Streptococcus pyogenes transcriptome changes in inflammatory environment of necrotizing fasciitis.

Hirose Y, Yamaguchi M, Okuzaki D, Motooka D, Hamamoto H, Hanada T, Sumitomo T, Nakata M, Kawabata S

Applied and Environmental Microbiology　2019/08　Research paper (scientific journal)

Polydomはフォン・レックリングハウゼン病の皮膚型神経線維腫形成メカニズムに関与する

神谷 智, 室田 浩之, 荒瀬 規子, 金田 眞理, 佐藤 涼子, 関口 清俊, 奥崎 大介, 元岡 大祐, 片山 一朗

日本レックリングハウゼン病学会雑誌　Vol. 10　No. 1　p. 41-42　2019/07

Urinary tract infection due to anaerobic bacteria in a two-month-old infant

Chiaki Tao, Noriko Kinoshita, Kensuke Shoji, Daisuke Motooka, Shota Nakamura, Rumiko Eura, Katsuhiko Ueoka, Mitsuru Kubota, Akira Ishiguro, Isao Miyairi

Journal of Infection and Chemotherapy　Vol. 25　No. 5　p. 368-370　2019/05　Research paper (scientific journal)

Spreading patterns of NDM-producing Enterobacteriaceae in clinical and environmental settings in Yangon, Myanmar

Yo Sugawara, Yukihiro Akeda, Hideharu Hagiya, Noriko Sakamoto, Dan Takeuchi, Rathina Kumar Shanmugakani, Daisuke Motooka, Isao Nishi, Khwar Nyo Zin, Mya Mya Aye, Thuzar Myint, Kazunori Tomono, Shigeyuki Hamada

Antimicrobial Agents and Chemotherapy　Vol. 63　No. 3　2019/03　Research paper (scientific journal)

Allergic conversion of protective mucosal immunity against nasal bacteria in patients with chronic rhinosinusitis with nasal polyposis

Kazuya Takeda, Shuhei Sakakibara, Kazuo Yamashita, Daisuke Motooka, Shota Nakamura, Marwa Ali El Hussien, Jun Katayama, Yohei Maeda, Masanobu Nakata, Shigeyuki Hamada, Daron M. Standley, Masaki Hayama, Takashi Shikina, Hidenori Inohara, Hitoshi Kikutani

Journal of Allergy and Clinical Immunology　Vol. 143　No. 3　p. 1163-1175.e15　2019/03　Research paper (scientific journal)

BATF2 prevents T-cell-mediated intestinal inflammation through regulation of the IL-23/IL-17 pathway

Hisako Kayama, Haruka Tani, Shoko Kitada, Anunya Opasawatchai, Ryu Okumura, Daisuke Motooka, Shota Nakamura, Kiyoshi Takeda

International Immunology　Vol. 31　No. 6　p. 371-383　2019/02/19　Research paper (scientific journal)

polydomはフォン・レックリングハウゼン病の皮膚型神経線維腫形成メカニズムを決定づける

神谷 智, 室田 浩之, 荒瀬 規子, 金田 眞理, 佐藤 涼子, 関口 清俊, 奥崎 大介, 元岡 大祐, 片山 一朗

日本レックリングハウゼン病学会学術大会プログラム・抄録集　Vol. 10回　p. 30-30　2019/02

Characterization of Vibrio cholerae isolates from two distinct Kenyan cholera outbreaks in 2007 and 2009

S. P. Awasthi, S. M. Saidi, N. Chowdhury, M. Asakura, P. H. Hoang, A. Hinenoya, D. Motooka, S. Nakamura, Y. Iijima, S. Yamasaki

2019/02　Research paper (international conference proceedings)

Coexistence Of plasmid-mediated mcr-1 And bla<inf>NDM-4</inf> genes in a Klebsiella pneumoniae clinical strain in Vietnam

Lien Le, Linh Khanh Tran, Tam Duong Le-Ha, Bich Phuong Tran, Hong Ngoc Le-Vo, Yen Nhi Nguyen, Hanh Lan Nguyen, Khanh Quynh Hoang-Ngoc, Yuki Matsumoto, Daisuke Motooka, Shota Nakamura, James W. Jones, Tetsuya Iida, Van Cao

Infection and Drug Resistance　Vol. 12　p. 3703-3707　2019　Research paper (scientific journal)

Complex class 1 integron in a clinical Escherichia coli strain from Vietnam carrying both mcr-1 and bla<inf>NDM-1</inf>

Hong Ngoc Le-Vo, Phuong Thi Bich Tran, Lien Le, Yuki Matsumoto, Daisuke Motooka, Shota Nakamura, James W. Jones, Tetsuya Iida, Van Cao

Frontiers in Microbiology　Vol. 10　No. OCT　2019　Research paper (scientific journal)

Diffusely adherent Escherichia coli strains isolated from healthy carriers suppress cytokine secretions of epithelial cells stimulated by inflammatory substances

Yoshihiko Tanimoto, Sayaka Tamai, Takehiro Matsuzaki, Narumi Takeuchi, Takumi Noju, Saki Yanagida, Eriko Kage-Nakadai, Yoshihiro Yamaguchi, Toshio Kodama, Shota Nakamura, Daisuke Motooka, Tetsuya Iida, Yoshikazu Nishikawaa

Infection and Immunity　Vol. 87　No. 1　2019/01/01　Research paper (scientific journal)

Comprehensive subspecies identification of 175 nontuberculous mycobacteria species based on 7547 genomic profiles

Yuki Matsumoto, Takeshi Kinjo, Daisuke Motooka, Daijiro Nabeya, Nicolas Jung, Kohei Uechi, Toshihiro Horii, Tetsuya Iida, Jiro Fujita, Shota Nakamura

Emerging Microbes and Infections　Vol. 8　No. 1　p. 1043-1053　2019/01/01　Research paper (scientific journal)

Characterization of a carbapenem- and colistin-resistant Enterobacter cloacae carrying Tn6901 in bla<inf>NDM-1</inf> genomic context

Tam Duong Le-Ha, Lien Le, Hong Ngoc Le-Vo, Mizue Anda, Daisuke Motooka, Shota Nakamura, Linh Khanh Tran, Phuong Thi Bich Tran, Tetsuya Iida, Van Cao

Infection and Drug Resistance　Vol. 12　p. 733-739　2019　Research paper (scientific journal)

A high-performance sequence analysis engine for shotgun metagenomics through GPU acceleration

Ying Feng Hsu, Morito Matsuoka, Nicolas Jung, Yuki Matsumoto, Daisuke Motooka, Shota Nakamura

Proceedings - 2018 IEEE 18th International Conference on Bioinformatics and Bioengineering, BIBE 2018　p. 54-60　2018/12/06　Research paper (international conference proceedings)

Streptococcus tigurinusによる重症軟部組織感染症の1例

吉澤 秀憲, 片田 竜一, 元岡 大祐, 松本 悠希, 中村 昇太, 松本 博志

日本法医学雑誌　Vol. 72　No. 2　p. 311-311　2018/12

Genomic characterization of carbapenemase-producing klebsiella pneumoniae with chromosomally carried bla<inf>NDM-1</inf>

Noriko Sakamoto, Yukihiro Akeda, Yo Sugawara, Dan Takeuchi, Daisuke Motooka, Norihisa Yamamoto, Warawut Laolerd, Pitak Santanirand, Shigeyuki Hamada

Antimicrobial Agents and Chemotherapy　Vol. 62　No. 12　2018/12　Research paper (scientific journal)

Identification of a Golgi GPI-N-acetylgalactosamine transferase with tandem transmembrane regions in the catalytic domain

Tetsuya Hirata, Sushil K. Mishra, Shota Nakamura, Kazunobu Saito, Daisuke Motooka, Yoko Takada, Noriyuki Kanzawa, Yoshiko Murakami, Yusuke Maeda, Morihisa Fujita, Yoshiki Yamaguchi, Taroh Kinoshita

Nature Communications　Vol. 9　No. 1　p. 405-405　2018/12/01　Research paper (scientific journal)

A convolutional neural network uses microscopic images to differentiate between mouse and human cell lines and their radioresistant clones

Masayasu Toratani, Masamitsu Konno, Ayumu Asai, Jun Koseki, Koichi Kawamoto, Keisuke Tamari, Zhihao Li, Daisuke Sakai, Toshihiro Kudo, Taroh Satoh, Katsutoshi Sato, Daisuke Motooka, Daisuke Okuzaki, Yuichiro Doki, Masaki Mori, Kazuhiko Ogawa, Hideshi Ishii

Cancer Research　Vol. 78　No. 23　p. 6703-6707　2018/12/01　Research paper (scientific journal)

A Novel Unifrac-Based Analytical Method for Determining Sequential Changes in Gut Microbiota after Hematopoietic Stem Cell Transplantation

Kusakabe Shinsuke, Fukushima Kentaro, Maeda Tetsuo, Yokota Takafumi, Nakai Ritsuko, Hino Akihisa, Nagate Yasuhiro, Fujita Jiro, Daisuke Motooka, Nakamura Shota, Shibayama Hirohiko, Kanakura Yuzuru

The American Society of Hematology 60th Annual Meeting　Vol. 132　2018/11

Extremely strong infiltration of WT1-specific CTLs into mouse tumor by the combination vaccine with WT1-specific CTL and helper peptides

Jun Nakata, Hiroko Nakajima, Hiromu Hayashibara, Kanako Imafuku, Soyoko Morimoto, Fumihiro Fujiki, Daisuke Motooka, Daisuke Okuzaki, Kana Hasegawa, Naoki Hosen, Akihiro Tsuboi, Yoshihiro Oka, Atsushi Kumanogoh, Yusuke Oji, Haruo Sugiyama

Oncotarget　Vol. 9　No. 89　p. 36029-36038　2018/11/01　Research paper (scientific journal)

Regnase-1 contro ls colon epithelial regeneration via regulation of mTOR and purine metabolism

Yasuharu Nagahama, Mayuko Shimoda, Guoliang Mao, Shailendra Kumar Singh, Yuuki Kozakai, Xin Sun, Daisuke Motooka, Shota Nakamura, Hiroki Tanaka, Takashi Satoh, Kazuhiko Maeda, Shizuo Akira

Proceedings of the National Academy of Sciences of the United States of America　Vol. 115　No. 43　p. 11036-11041　2018/10/23　Research paper (scientific journal)

High salt intake increases plasma trimethylamine N-oxide (TMAO) concentration and produces gut dysbiosis in rats

Klaudia Bielinska, Marek Radkowski, Marta Grochowska, Karol Perlejewski, Tomasz Huc, Kinga Jaworska, Daisuke Motooka, Shota Nakamura, Marcin Ufnal

Nutrition　Vol. 54　p. 33-39　2018/10　Research paper (scientific journal)

WU polyomavirus detected in children with severe respiratory failure

Kazuhiro Uda, Chitose Koyama-Wakai, Kensuke Shoji, Noriyasu Iwase, Daisuke Motooka, Shota Nakamura, Isao Miyairi

Journal of Clinical Virology　Vol. 107　p. 25-28　2018/10　Research paper (scientific journal)

Heme ameliorates dextran sodium sulfate-induced colitis through providing intestinal macrophages with noninflammatory profiles

Hisako Kayama, Masako Kohyama, Daisuke Okuzaki, Daisuke Motooka, Soumik Barman, Ryu Okumura, Masato Muneta, Katsuaki Hoshino, Izumi Sasaki, Wataru Ise, Hiroshi Matsuno, Junichi Nishimura, Tomohiro Kurosaki, Shota Nakamura, Hisashi Arase, Tsuneyasu Kaisho, Kiyoshi Takeda

Proceedings of the National Academy of Sciences of the United States of America　Vol. 115　No. 33　p. 8418-8423　2018/08/14　Research paper (scientific journal)

Wilms tumour 1 peptide vaccine as a cure-oriented post-chemotherapy strategy for patients with acute myeloid leukaemia at high risk of relapse

Jun Nakata, Yoshiki Nakae, Manabu Kawakami, Soyoko Morimoto, Daisuke Motooka, Naoki Hosen, Fumihiro Fujiki, Hiroko Nakajima, Kana Hasegawa, Sumiyuki Nishida, Akihiro Tsuboi, Yusuke Oji, Yoshihiro Oka, Atsushi Kumanogoh, Haruo Sugiyama

British Journal of Haematology　Vol. 182　No. 2　p. 287-290　2018/07

The presence of colistin resistance gene mcr-1 and -3 in ESBL producing Escherichia coli isolated from food in Ho Chi Minh City, Vietnam

Takahiro Yamaguchi, Ryuji Kawahara, Kazuo Harada, Shihono Teruya, Tatsuya Nakayama, Daisuke Motooka, Shota Nakamura, Phuc Do Nguyen, Yuko Kumeda, Chinh Van Dang, Kazumasa Hirata, Yoshimasa Yamamoto

FEMS Microbiology Letters　Vol. 365　No. 11　2018/06/01

A case of severe soft tissue infection due to Streptococcus tigurinus diagnosed by necropsy in which genomic analysis was useful for clarifying its pathogenicity

Hidenori Yoshizawa, Daisuke Motooka, Yuki Matsumoto, Ryuichi Katada, Shota Nakamura, Eiichi Morii, Tetsuya Iida, Hiroshi Matsumoto

Pathology International　Vol. 68　No. 5　p. 301-306　2018/05　Research paper (scientific journal)

Molecular characterization of imp-1-producing enterobacter cloacae complex isolates in Tokyo

Kotaro Aoki, Sohei Harada, Koji Yahara, Yoshikazu Ishii, Daisuke Motooka, Shota Nakamura, Yukihiro Akeda, Tetsuya Iida, Kazunori Tomono, Satoshi Iwata, Kyoji Moriya, Kazuhiro Tateda

Antimicrobial Agents and Chemotherapy　Vol. 62　No. 3　2018/03　Research paper (scientific journal)

Molecular characterization of imp-1-producing enterobacter cloacae complex isolates in Tokyo

Kotaro Aoki, Sohei Harada, Koji Yahara, Yoshikazu Ishii, Daisuke Motooka, Shota Nakamura, Yukihiro Akeda, Tetsuya Iida, Kazunori Tomono, Satoshi Iwata, Kyoji Moriya, Kazuhiro Tateda

Antimicrobial Agents and Chemotherapy　Vol. 62　No. 3　2018/03　Research paper (scientific journal)

N-Glycan-dependent protein folding and endoplasmic reticulum retention regulate GPI-anchor processing

Yi Shi Liu, Xin Yu Guo, Tetsuya Hirata, Yao Rong, Daisuke Motooka, Toshihiko Kitajima, Yoshiko Murakami, Xiao Dong Gao, Shota Nakamura, Taroh Kinoshita, Morihisa Fujita

Journal of Cell Biology　Vol. 217　No. 2　p. 585-599　2018/02/01　Research paper (scientific journal)

Corrigendum to “Plasmid dynamics in Vibrio parahaemolyticus strains related to shrimp Acute Hepatopancreatic Necrosis Syndrome (AHPNS)” [Infect. Genet. Evol. (2017) 51: 211–218] (S156713481730120X) (10.1016/j.meegid.2017.04.007))

Chonchanok Theethakaew, Shota Nakamura, Daisuke Motooka, Shigeaki Matsuda, Toshio Kodama, Kaknokrat Chonsin, Orasa Suthienkul, Tetsuya Iida

Infection, Genetics and Evolution　Vol. 57　2018/01/01　Research paper (scientific journal)

Non-ischemic heart failure with reduced ejection fraction is associated with altered intestinal microbiota

Themistoklis Katsimichas, Tomohito Ohtani, Daisuke Motooka, Yasumasa Tsukamoto, Hidetaka Kioka, Kei Nakamoto, Shozo Konishi, Misato Chimura, Kaoruko Sengoku, Hiroshi Miyawaki, Taiki Sakaguchi, Ryu Okumura, Konstantinos Theofilis, Tetsuya Iida, Kiyoshi Takeda, Shota Nakamura, Yasushi Sakata

Circulation Journal　Vol. 82　No. 6　p. 1640-1650　2018　Research paper (scientific journal)

Highly sensitive detection of ESR1 mutations in cell-free DNA from patients with metastatic breast cancer using molecular barcode sequencing

Nanae Masunaga, Naofumi Kagara, Daisuke Motooka, Shota Nakamura, Tomohiro Miyake, Tomonori Tanei, Yasuto Naoi, Masafumi Shimoda, Kenzo Shimazu, Seung Jin Kim, Shinzaburo Noguchi

Breast Cancer Research and Treatment　Vol. 167　No. 1　p. 49-58　2018/01/01　Research paper (scientific journal)

Hydrogen-rich saline regulates intestinal barrier dysfunction, dysbiosis, and bacterial translocation in a murine model of sepsis

Mitsunori Ikeda, Kentaro Shimizu, Hiroshi Ogura, Takashi Kurakawa, Eiji Umemoto, Daisuke Motooka, Shota Nakamura, Naotsugu Ichimaru, Kiyoshi Takeda, Shiro Takahara, Hirano Shin-Ichi, Takeshi Shimazu

Shock　Vol. 50　No. 6　p. 640-647　2018　Research paper (scientific journal)

Clonal evolution and antigen recognition of anti-nuclear antibodies in acute systemic lupus erythematosus

Shuhei Sakakibara, Takao Arimori, Kazuo Yamashita, Hideyuki Jinzai, Daisuke Motooka, Shota Nakamura, Songling Li, Kazuya Takeda, Jun Katayama, Marwa Ali El Hussien, Masashi Narazaki, Toshio Tanaka, Daron M. Standley, Junichi Takagi, Hitoshi Kikutani

Scientific Reports　Vol. 7　No. 1　2017/12/01　Research paper (scientific journal)

Mutation accumulation under UV radiation in Escherichia coli

Atsushi Shibai, Yusuke Takahashi, Yuka Ishizawa, Daisuke Motooka, Shota Nakamura, Bei Wen Ying, Saburo Tsuru

Scientific Reports　Vol. 7　No. 1　2017/12/01　Research paper (scientific journal)

Clonal evolution and antigen recognition of anti-nuclear antibodies in acute systemic lupus erythematosus

Shuhei Sakakibara, Takao Arimori, Kazuo Yamashita, Hideyuki Jinzai, Daisuke Motooka, Shota Nakamura, Songling Li, Kazuya Takeda, Jun Katayama, Marwa Ali El Hussien, Masashi Narazaki, Toshio Tanaka, Daron M. Standley, Junichi Takagi, Hitoshi Kikutani

Scientific Reports　Vol. 7　No. 1　2017/12/01　Research paper (scientific journal)

Suppression of HBV replication by the expression of nickase-and nuclease dead-Cas9

Takeshi Kurihara, Takasuke Fukuhara, Chikako Ono, Satomi Yamamoto, Kentaro Uemura, Toru Okamoto, Masaya Sugiyama, Daisuke Motooka, Shota Nakamura, Masato Ikawa, Masashi Mizokami, Yoshihiko Maehara, Yoshiharu Matsuura

Scientific Reports　Vol. 7　No. 1　2017/12/01　Research paper (scientific journal)

Sensitivity of next-generation sequencing metagenomic analysis for detection of RNA and DNA viruses in cerebrospinal fluid: The confounding effect of background contamination

Iwona Bukowska-Ośko, Karol Perlejewski, Shota Nakamura, Daisuke Motooka, Tomasz Stokowy, Joanna Kosińska, Marta Popiel, Rafał Płoski, Andrzej Horban, Dariusz Lipowski, Kamila Caraballo Cortés, Agnieszka Pawełczyk, Urszula Demkow, Adam Stępień, Marek Radkowski, Tomasz Laskus

Advances in Experimental Medicine and Biology　Vol. 944　p. 53-62　2017/11/01　Research paper (scientific journal)

The cell envelope-associated phospholipid-binding protein LmeA is required for mannan polymerization in mycobacteria

Kathryn C. Rahlwes, Stephanie A. Ha, Daisuke Motooka, Jacob A. Mayfield, Lisa R. Baumoel, Justin N. Strickland, Ana P. Torres-Ocampo, Shota Nakamura, Yasu S. Morita

Journal of Biological Chemistry　Vol. 292　No. 42　p. 17407-17417　2017/10/20　Research paper (scientific journal)

Erratum: Addendum: Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment (Nature immunology (2017) 18 2 (173-183))

Yohko Kitagawa, Naganari Ohkura, Yujiro Kidani, Alexis Vandenbon, Keiji Hirota, Ryoji Kawakami, Keiko Yasuda, Daisuke Motooka, Shota Nakamura, Motonari Kondo, Ichiro Taniuchi, Terumi Kohwi-Shigematsu, Shimon Sakaguchi

Nature immunology　Vol. 18　No. 11　2017/10/18　Research paper (scientific journal)

Genome-Wide Screening Uncovers the Significance of N-sulfation of Heparan Sulfate as a Host Cell Factor for Chikungunya Virus Infection

Atsushi Tanaka, Uranan Tumkosit, Shota Nakamura, Daisuke Motooka, Natsuko Kishishita, Thongkoon Priengprom, Areerat Sa-ngasang, Taroh Kinoshita, Naokazu Takeda, Yusuke Maeda

2017/10

Genetic characterization of bla<inf>NDM</inf>-harboring plasmids in carbapenem-resistant Escherichia coli from Myanmar

Yo Sugawara, Yukihiro Akeda, Noriko Sakamoto, Dan Takeuchi, Daisuke Motooka, Shota Nakamura, Hideharu Hagiya, Norihisa Yamamoto, Isao Nishi, Hisao Yoshida, Kazuhisa Okada, Khwar Nyo Zin, Mya Mya Aye, Kazunori Tonomo, Shigeyuki Hamada

PLoS ONE　Vol. 12　No. 9　2017/09　Research paper (scientific journal)

Indigo Naturalis ameliorates murine dextran sodium sulfate-induced colitis via aryl hydrocarbon receptor activation

Shoichiro Kawai, Hideki Iijima, Shinichiro Shinzaki, Satoshi Hiyama, Toshio Yamaguchi, Manabu Araki, Shuko Iwatani, Eri Shiraishi, Akira Mukai, Takahiro Inoue, Yoshito Hayashi, Masahiko Tsujii, Daisuke Motooka, Shota Nakamura, Tetsuya Iida, Tetsuo Takehara

Journal of Gastroenterology　Vol. 52　No. 8　p. 904-919　2017/08/01　Research paper (scientific journal)

The clinical and phylogenetic investigation for a nosocomial outbreak of respiratory syncytial virus infection in an adult hemato-oncology unit

Daijiro Nabeya, Takeshi Kinjo, Gretchen Lynn Parrott, Ayako Uehara, Daisuke Motooka, Shota Nakamura, Saifun Nahar, Sawako Nakachi, Masashi Nakamatsu, Sakuko Maeshiro, Shusaku Haranaga, Masao Tateyama, Takeaki Tomoyose, Hiroaki Masuzaki, Toshihiro Horii, Jiro Fujita

Journal of Medical Virology　Vol. 89　No. 8　p. 1364-1372　2017/08　Research paper (scientific journal)

Genome-wide screening uncovers the significance of N-sulfation of heparan sulfate as a host cell factor for chikungunya virus infection

Atsushi Tanaka, Uranan Tumkosit, Shota Nakamura, Daisuke Motooka, Natsuko Kishishita, Thongkoon Priengprom, Areerat Sa-ngasang, Taroh Kinoshita, Naokazu Takeda, Yusuke Maeda

Journal of Virology　Vol. 91　No. 13　2017/07/01　Research paper (scientific journal)

Plasmid dynamics in Vibrio parahaemolyticus strains related to shrimp Acute Hepatopancreatic Necrosis Syndrome (AHPNS)

Chonchanok Theethakaew, Shota Nakamura, Daisuke Motooka, Shigeaki Matsuda, Toshio Kodama, Kaknokrat Chonsin, Orasa Suthienkul, Tetsuya Iida

Infection, Genetics and Evolution　Vol. 51　p. 211-218　2017/07/01　Research paper (scientific journal)

Phenotype–genotype correlations of PIGO deficiency with variable phenotypes from infantile lethality to mild learning difficulties

Junpei Tanigawa, Haruka Mimatsu, Seiji Mizuno, Nobuhiko Okamoto, Daisuke Fukushi, Koji Tominaga, Hiroyuki Kidokoro, Yukako Muramatsu, Eriko Nishi, Shota Nakamura, Daisuke Motooka, Noriko Nomura, Kiyoshi Hayasaka, Tetsuya Niihori, Yoko Aoki, Shin Nabatame, Masahiro Hayakawa, Jun Natsume, Keiichi Ozono, Taroh Kinoshita, Nobuaki Wakamatsu, Yoshiko Murakami

Human Mutation　Vol. 38　No. 7　p. 805-815　2017/07　Research paper (scientific journal)

重症軟部組織感染症に対し起炎菌同定を行った一例

吉澤 秀憲, 片田 竜一, 元岡 大祐, 中間 健太郎, 石田 季子, 中村 昇太, 松本 博志

日本法医学雑誌　Vol. 71　No. 1　p. 57-57　2017/05

Characterization of miR-122-independent propagation of HCV

Chikako Ono, Takasuke Fukuhara, Daisuke Motooka, Shota Nakamura, Daisuke Okuzaki, Satomi Yamamoto, Tomokazu Tamura, Hiroyuki Mori, Asuka Sato, Kentaro Uemura, Yuzy Fauzyah, Takeshi Kurihara, Takahiro Suda, Akira Nishio, Su Su Hmwe, Toru Okamoto, Tomohide Tatsumi, Tetsuo Takehara, Kazuaki Chayama, Takaji Wakita, Kazuhiko Koike, Yoshiharu Matsuura

PLoS Pathogens　Vol. 13　No. 5　2017/05　Research paper (scientific journal)

Erratum: Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment

Yohko Kitagawa, Naganari Ohkura, Yujiro Kidani, Alexis Vandenbon, Keiji Hirota, Ryoji Kawakami, Keiko Yasuda, Daisuke Motooka, Shota Nakamura, Motonari Kondo, Ichiro Taniuchi, Terumi Kohwi-Shigematsu, Shimon Sakaguchi

Nature immunology　Vol. 18　No. 4　2017/03/22　Research paper (scientific journal)

Quasispecies of Hepatitis C Virus Participate in Cell-Specific Infectivity

Takasuke Fukuhara, Satomi Yamamoto, Chikako Ono, Shota Nakamura, Daisuke Motooka, Hiroyuki Mori, Takeshi Kurihara, Asuka Sato, Tomokazu Tamura, Takashi Motomura, Toru Okamoto, Michio Imamura, Toru Ikegami, Tomoharu Yoshizumi, Yuji Soejima, Yoshihiko Maehara, Kazuaki Chayama, Yoshiharu Matsuura

Scientific Reports　Vol. 7　p. 45228-45228　2017/03/22　Research paper (scientific journal)

Streptococcus tigurinusによる軟部組織感染症に対しネクロプシーを行った一例

吉澤 秀憲, 元岡 大祐, 中村 昇太, 森井 英一, 松本 博志

日本病理学会会誌　Vol. 106　No. 1　p. 479-479　2017/03

Postnatal changes in the relative abundance of intestinal Lactobacillus spp. In newborn calves

Tadashi Takino, Yuko Kato-Mori, Daisuke Motooka, Shota Nakamura, Tetsuya Iida, Katsuro Hagiwara

Journal of Veterinary Medical Science　Vol. 79　No. 3　p. 452-455　2017/03　Research paper (scientific journal)

Fungal ITS1 deep-sequencing strategies to reconstruct the composition of a 26-species community and evaluation of the gut mycobiota of healthy Japanese individuals

Daisuke Motooka, Kosuke Fujimoto, Reiko Tanaka, Takashi Yaguchi, Kazuyoshi Gotoh, Yuichi Maeda, Yoki Furuta, Takashi Kurakawa, Naohisa Goto, Teruo Yasunaga, Masashi Narazaki, Atsushi Kumanogoh, Toshihiro Horii, Tetsuya Iida, Kiyoshi Takeda, Shota Nakamura

Frontiers in Microbiology　Vol. 8　No. FEB　2017/02/15　Research paper (scientific journal)

生体RNAシークエンス分析から明らかになったBordetella pertussis感染に対する新規の抗原(In vivo RNA-seq reveals novel antigens against Bordetella pertussis infection)

鈴木 孝一朗, 新澤 直明, 元岡 大祐, 中村 昇太, 石垣 佳祐, 生田 和良, 山西 弘一, 堀口 安彦

日本細菌学雑誌　Vol. 72　No. 1　p. 60-60　2017/02

Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment

Yohko Kitagawa, Naganari Ohkura, Yujiro Kidani, Alexis Vandenbon, Keiji Hirota, Ryoji Kawakami, Keiko Yasuda, Daisuke Motooka, Shota Nakamura, Motonari Kondo, Ichiro Taniuchi, Terumi Kohwi-Shigematsu, Shimon Sakaguchi

Nature Immunology　Vol. 18　No. 2　p. 173-183　2017/02/01　Research paper (scientific journal)

Whole-genome sequence of Streptococcus tigurinus strain osk_001, isolated from postmortem material

Hidenori Yoshizawa, Daisuke Motooka, Ryuichi Katada, Yuki Matsumoto, Shota Nakamura, Eiichi Morii, Tetsuya Iida, Hiroshi Matsumoto

Genome Announcements　Vol. 5　No. 35　2017　Research paper (scientific journal)

Draft genome sequence of Plasmodium gonderi, a malaria parasite of African Old World monkeys

Hajime Honma, Satoru Kawai, Daisuke Motooka, Shota Nakamura, Takahiro Tougan, Toshihiro Horii, Nobuko Arisue

Genome Announcements　Vol. 5　No. 28　p. e00612-17　2017　Research paper (scientific journal)

Herpes zoster laryngitis in a patient treated with fingolimod

Hideharu Hagiya, Hisao Yoshida, Mikito Shimizu, Daisuke Motooka, Shota Nakamura, Tetsuya Iida, Norihisa Yamamoto, Yukihiro Akeda, Kazunori Tomono

Journal of Infection and Chemotherapy　Vol. 22　No. 12　p. 830-832　2016/12/01　Research paper (scientific journal)

Herpes zoster laryngitis in a patient treated with fingolimod

Hideharu Hagiya, Hisao Yoshida, Mikito Shimizu, Daisuke Motooka, Shota Nakamura, Tetsuya Iida, Norihisa Yamamoto, Yukihiro Akeda, Kazunori Tomono

Journal of Infection and Chemotherapy　Vol. 22　No. 12　p. 830-832　2016/12/01　Research paper (scientific journal)

Dysbiosis Contributes to Arthritis Development via Activation of Autoreactive T Cells in the Intestine

Yuichi Maeda, Takashi Kurakawa, Eiji Umemoto, Daisuke Motooka, Yoshinaga Ito, Kazuyoshi Gotoh, Keiji Hirota, Masato Matsushita, Yoki Furuta, Masashi Narazaki, Noriko Sakaguchi, Hisako Kayama, Shota Nakamura, Tetsuya Iida, Yukihiko Saeki, Atsushi Kumanogoh, Shimon Sakaguchi, Kiyoshi Takeda

Arthritis and Rheumatology　Vol. 68　No. 11　p. 2646-2661　2016/11/01　Research paper (scientific journal)

Dysbiosis Contributes to Arthritis Development via Activation of Autoreactive T Cells in the Intestine

Yuichi Maeda, Takashi Kurakawa, Eiji Umemoto, Daisuke Motooka, Yoshinaga Ito, Kazuyoshi Gotoh, Keiji Hirota, Masato Matsushita, Yoki Furuta, Masashi Narazaki, Noriko Sakaguchi, Hisako Kayama, Shota Nakamura, Tetsuya Iida, Yukihiko Saeki, Atsushi Kumanogoh, Shimon Sakaguchi, Kiyoshi Takeda

Arthritis and Rheumatology　Vol. 68　No. 11　p. 2646-2661　2016/11/01　Research paper (scientific journal)

G28A mutation is necessary for an efficient propagation of HCV in miR-122 deficient condition

Chikako Ono, Takasuke Fukuhara, Daisuke Motooka, Shota Nakamura, Satomi Yamamoto, Hiroyuki Mori, Kentaro Uemura, Toru Okamoto, Su Su Hmwe, Kazuaki Chayama, Takaji Wakita, Kazuhiko Koike, Yoshiharu Matsuura

2016/10　Research paper (international conference proceedings)

G28A mutation facilitates an efficient propagation of HCV in miR-122-independent manner

Chikako Ono, Takasuke Fukuhara, Daisuke Motooka, Shota Nakamura, Satomi Yamamoto, Hiroyuki Mori, Kentaro Uemura, Toru Okamoto, Su Su Hmwe, Kazuaki Chayama, Takaji Wakita, Kazuhiko Koike, Yoshiharu Matsuura

2016/10　Research paper (other academic)

Enterococcus saigonensis sp. nov., isolated from retail chicken meat and liver

Tetsuya Harada, Van Chinh Dang, Do Phuc Nguyen, Thi Anh Dao Nguyen, Mitsuo Sakamoto, Moriya Ohkuma, Daisuke Motooka, Shota Nakamura, Kotaro Uchida, Michio Jinnai, Shinya Yonogi, Ryuji Kawahara, Masashi Kanki, Takao Kawai, Yuko Kumeda, Yoshimasa Yamamoto

International Journal of Systematic and Evolutionary Microbiology　Vol. 66　No. 10　p. 3779-3785　2016/10　Research paper (scientific journal)

From Bedside to Lab,from Lab to Bedside 救急医学研究を発展させるために 侵襲病態における腸内フローラに関する研究と臨床への応用

池田 光憲, 清水 健太郎, 倉川 尚, 梅本 英司, 元岡 大祐, 中村 昇太, 小倉 裕司, 嶋津 岳士

日本救急医学会雑誌　Vol. 27　No. 9　p. 328-328　2016/09

Temporal dynamics of bacterial microbiota in the human oral cavity determined using an in situ model of dental biofilms

Nanako Wake, Yoko Asahi, Yuichiro Noiri, Mikako Hayashi, Daisuke Motooka, Shota Nakamura, Kazuyoshi Gotoh, Jiro Miura, Hiroyuki Machi, Tetsuya Iida, Shigeyuki Ebisu

npj Biofilms and Microbiomes　Vol. 2　2016/08/10　Research paper (scientific journal)

LATS2 positively regulates polycomb repressive complex 2

Kosuke Torigata, Okuzaki Daisuke, Satomi Mukai, Akira Hatanaka, Fumiharu Ohka, Daisuke Motooka, Shota Nakamura, Yasuyuki Ohkawa, Norikazu Yabuta, Yutaka Kondo, Hiroshi Nojima

PLoS ONE　Vol. 11　No. 7　2016/07/01　Research paper (scientific journal)

Metagenomic Analysis Reveals Dynamic Changes of Whole Gut Microbiota in the Acute Phase of Intensive Care Unit Patients

Masahiro Ojima, Daisuke Motooka, Kentaro Shimizu, Kazuyoshi Gotoh, Ayumi Shintani, Kazuhisa Yoshiya, Shota Nakamura, Hiroshi Ogura, Tetsuya Iida, Takeshi Shimazu

Digestive Diseases and Sciences　Vol. 61　No. 6　p. 1628-1634　2016/06/01　Research paper (scientific journal)

Lypd8 promotes the segregation of flagellated microbiota and colonic epithelia

Ryu Okumura, Takashi Kurakawa, Takashi Nakano, Hisako Kayama, Makoto Kinoshita, Daisuke Motooka, Kazuyoshi Gotoh, Taishi Kimura, Naganori Kamiyama, Takashi Kusu, Yoshiyasu Ueda, Hong Wu, Hideki Iijima, Soumik Barman, Hideki Osawa, Hiroshi Matsuno, Junichi Nishimura, Yusuke Ohba, Shota Nakamura, Tetsuya Iida, Masahiro Yamamoto, Eiji Umemoto, Koichi Sano, Kiyoshi Takeda

NATURE　Vol. 532　No. 7597　p. 117-+　2016/04　Research paper (scientific journal)

Lypd8 promotes the segregation of flagellated microbiota and colonic epithelia

Ryu Okumura, Takashi Kurakawa, Takashi Nakano, Hisako Kayama, Makoto Kinoshita, Daisuke Motooka, Kazuyoshi Gotoh, Taishi Kimura, Naganori Kamiyama, Takashi Kusu, Yoshiyasu Ueda, Hong Wu, Hideki Iijima, Soumik Barman, Hideki Osawa, Hiroshi Matsuno, Junichi Nishimura, Yusuke Ohba, Shota Nakamura, Tetsuya Iida, Masahiro Yamamoto, Eiji Umemoto, Koichi Sano, Kiyoshi Takeda

Nature　Vol. 532　No. 7597　p. 117-121　2016/04　Research paper (scientific journal)

Homo-trimeric Structure of the Type IVb Minor Pilin CofB Suggests Mechanism of CFA/III Pilus Assembly in Human Enterotoxigenic Escherichia coli

Kazuki Kawahara, Hiroya Oki, Shunsuke Fukakusa, Takuya Yoshida, Tomoya Imai, Takahiro Maruno, Yuji Kobayashi, Daisuke Motooka, Tetsuya Iida, Tadayasu Ohkubo, Shota Nakamura

Journal of Molecular Biology　Vol. 428　No. 6　p. 1209-1226　2016/03/27　Research paper (scientific journal)

生体におけるRNAシークエンス分析から明らかになった百日咳菌Bordetella pertussisの宿主内における感染に関連した遺伝子発現パターン(In vivo RNA-seq revealed infection-linked expression pattern of Bordetella pertussis within host)

新澤 直明, 鈴木 孝一朗, 元岡 大祐, 中村 昇太, 堀口 安彦

日本細菌学雑誌　Vol. 71　No. 1　p. 133-133　2016/02

Reductive evolution towards primitive life: What will we see?

Atsushi Shibai, Daisuke Motooka, Shota Nakamura, Saburo Tsuru

Proceedings of the Artificial Life Conference 2016, ALIFE 2016　p. 188-189　2016　Research paper (international conference proceedings)

An epidemiological analysis of summer influenza epidemics in Okinawa

Satoko Sunagawa, Yoshikazu Iha, Katsuya Taira, Sho Okano, Takeshi Kinjo, Futoshi Higa, Kazufumi Kuba, Masao Tateyama, Katsunori Nakamura, Shota Nakamura, Daisuke Motooka, Toshihiro Horii, Gretchen L. Parrott, Jiro Fujita

Internal Medicine　Vol. 55　No. 24　p. 3579-3584　2016　Research paper (scientific journal)

Metagenomic analysis of cerebrospinal fluid from patients with multiple sclerosis

Karol Perlejewski, Iwona Bukowska-Ośko, Shota Nakamura, Daisuke Motooka, Tomasz Stokowy, Rafał Płoski, Małgorzata Rydzanicz, Beata Zakrzewska-Pniewska, Aleksandra Podlecka-Piętowska, Monika Nojszewska, Anna Gogol, Kamila Caraballo Cortés, Urszula Demkow, Adam Stępień, Tomasz Laskus, Marek Radkowski

Advances in Experimental Medicine and Biology　Vol. 935　p. 89-98　2016　Part of collection (book)

Interaction of Vibrio parahaemolyticus diarrheal T3SS effector VopV with actin filaments

Mitsuhiro Nishimura, Takashi Fujii, Hirotaka Hiyoshi, Fumiaki Makino, Hajime Inoue, Daisuke Motooka, Toshio Kodama, Tadayasu Ohkubo, Yuji Kobayashi, Shota Nakamura, Keiichi Namba, Tetsuya Iida

2016/01　Research paper (international conference proceedings)

A novel PIGN mutation and prenatal diagnosis of inherited glycosylphosphatidylinositol deficiency

Taku Nakagawa, Mariko Taniguchi-Ikeda, Yoshiko Murakami, Shota Nakamura, Daisuke Motooka, Tomomi Emoto, Wataru Satake, Masahiro Nishiyama, Daisaku Toyoshima, Naoya Morisada, Satoshi Takada, Shinya Tairaku, Nobuhiko Okamoto, Ichiro Morioka, Hiroki Kurahashi, Tatsushi Toda, Taroh Kinoshita, Kazumoto Iijima

American Journal of Medical Genetics, Part A　Vol. 170　No. 1　p. 183-188　2016/01/01　Research paper (scientific journal)

Next-generation sequencing (NGS) in the identification of encephalitis-causing viruses: Unexpected detection of human herpesvirus 1 while searching for RNA pathogens

Karol Perlejewski, Marta Popiel, Tomasz Laskus, Shota Nakamura, Daisuke Motooka, Tomasz Stokowy, Dariusz Lipowski, Agnieszka Pollak, Urszula Lechowicz, Kamila Caraballo Cortés, Adam Stepień, Marek Radkowski, Iwona Bukowska-Ośko

Journal of Virological Methods　Vol. 226　p. 1-6　2015/12/15　Research paper (scientific journal)

Genomic confirmation of nutrient-dependent mutability of mutators in Escherichia coli

Saburo Tsuru, Yuuka Ishizawa, Atsushi Shibai, Yusuke Takahashi, Daisuke Motooka, Shota Nakamura, Tetsuya Yomo

Genes to Cells　Vol. 20　No. 12　p. 972-981　2015/12/01　Research paper (scientific journal)

PacBioを用いたHIV薬剤標的遺伝子領域の多様性解析

林晴香, 元岡大祐, 中山英美, 渡邊大, 白阪琢磨, 塩田達雄, 中村昇太, 飯田哲也

2015/11　Research paper (other academic)

Functional specialization in regulation and quality control in thermal adaptive evolution

Kazuma Yama, Yuki Matsumoto, Yoshie Murakami, Shigeto Seno, Hideo Matsuda, Kazuyoshi Gotoh, Daisuke Motooka, Shota Nakamura, Bei Wen Ying, Tetsuya Yomo

Genes to Cells　Vol. 20　No. 11　p. 943-955　2015/11　Research paper (scientific journal)

Genome-wide screening of genes required for glycosylphosphatidylinositol biosynthesis

Yao Rong, Shota Nakamura, Tetsuya Hirata, Daisuke Motooka, Yi Shi Liu, Zeng An He, Xiao Dong Gao, Yusuke Maeda, Taroh Kinoshita, Morihisa Fujita

PLoS ONE　Vol. 10　No. 9　2015/09/18　Research paper (scientific journal)

Post-Golgi anterograde transport requires GARP-dependent endosome-to-TGN retrograde transport

Tetsuya Hirata, Morihisa Fujita, Shota Nakamura, Kazuyoshi Gotoh, Daisuke Motooka, Yoshiko Murakami, Yusuke Maeda, Taroh Kinoshita

Molecular Biology of the Cell　Vol. 26　No. 17　p. 3071-3084　2015/09/01　Research paper (scientific journal)

A repeat unit of Vibrio diarrheal T3S effector subverts cytoskeletal actin homeostasis via binding to interstrand region of actin filaments

Mitsuhiro Nishimura, Takashi Fujii, Hirotaka Hiyoshi, Fumiaki Makino, Hajime Inoue, Daisuke Motooka, Toshio Kodama, Tadayasu Ohkubo, Yuji Kobayashi, Shota Nakamura, Keiichi Namba, Tetsuya Iida

Scientific Reports　Vol. 5　2015/06/03　Research paper (scientific journal)

Cloning, expression, purification, crystallization and X-ray crystallographic analysis of CofB, the minor pilin subunit of CFA/III from human enterotoxigenic Escherichia coli

Kazuki Kawahara, Hiroya Oki, Shunsuke Fukakusa, Takahiro Maruno, Yuji Kobayashi, Daisuke Motooka, Tooru Taniguchi, Takeshi Honda, Tetsuya Iida, Shota Nakamura, Tadayasu Ohkubo

Acta Crystallographica Section F:Structural Biology Communications　Vol. 71　p. 663-667　2015/06/01　Research paper (scientific journal)

Cloning, expression, purification, crystallization and X-ray crystallographic analysis of CofB, the minor pilin subunit of CFA/III from human enterotoxigenic Escherichia coli

Kazuki Kawahara, Hiroya Oki, Shunsuke Fukakusa, Takahiro Maruno, Yuji Kobayashi, Daisuke Motooka, Tooru Taniguchi, Takeshi Honda, Tetsuya Iida, Shota Nakamura, Tadayasu Ohkubo

ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS　Vol. 71　No. Pt 6　p. 663-667　2015/06　Research paper (scientific journal)

Periodic pattern of genetic and fitness diversity during evolution of an artificial cell-like system

Norikazu Ichihashi, Takuyo Aita, Daisuke Motooka, Shota Nakamura, Tetsuya Yomo

Molecular Biology and Evolution　Vol. 32　No. 12　p. 3205-3214　2015　Research paper (scientific journal)

Viral detection by high-throughput sequencing

Daisuke Motooka, Shota Nakamura, Katsuro Hagiwara, Takaaki Nakaya

Methods in Molecular Biology　Vol. 1236　p. 125-134　2015　Research paper (scientific journal)

Complete nucleotide sequence of a plasmid containing the botulinum neurotoxin gene in Clostridium botulinum type B strain 111 isolated from an infant patient in Japan

Koji Hosomi, Yoshihiko Sakaguchi, Tomoko Kohda, Kazuyoshi Gotoh, Daisuke Motooka, Shota Nakamura, Kaoru Umeda, Tetsuya Iida, Shunji Kozaki, Masafumi Mukamoto

Molecular Genetics and Genomics　Vol. 289　No. 6　p. 1267-1274　2014/11/19　Research paper (scientific journal)

Endosomes-to-TGN retrograde transport mediated by GARP is required for post-Golgi anterograde transport and glycosylation

Tetsuya Hirata, Morihisa Fujita, Shota Nakamura, Kazuyoshi Gotoh, Daisuke Motooka, Yoshiko Murakami, Yusuke Maeda, Taroh Kinoshita

GLYCOBIOLOGY　Vol. 24　No. 11　p. 1188-1189　2014/11　Research paper (international conference proceedings)

Performance comparison of second- and third-generation sequencers using a bacterial genome with two chromosomes

Mari Miyamoto, Daisuke Motooka, Kazuyoshi Gotoh, Takamasa Imai, Kazutoshi Yoshitake, Naohisa Goto, Tetsuya Iida, Teruo Yasunaga, Toshihiro Horii, Kazuharu Arakawa, Masahiro Kasahara, Shota Nakamura

BMC Genomics　Vol. 15　No. 1　2014/08/21　Research paper (scientific journal)

Oral pathobiont induces systemic inflammation and metabolic changes associated with alteration of gut microbiota

Kei Arimatsu, Hitomi Yamada, Haruna Miyazawa, Takayoshi Minagawa, Mayuka Nakajima, Mark I. Ryder, Kazuyoshi Gotoh, Daisuke Motooka, Shota Nakamura, Tetsuya Iida, Kazuhisa Yamazaki

Scientific Reports　Vol. 4　No. 4　2014/05/06　Research paper (scientific journal)

Peyer's patches play a protective role in nonsteroidal anti-inflammatory drug-induced enteropathy in mice

Satoshi Hiyama, Hideki Iijima, Shinichiro Shinzaki, Takahiro Inoue, Eri Shiraishi, Shoichiro Kawai, Manabu Araki, Motohiko Kato, Yoshito Hayashi, Tsutomu Nishida, Hironobu Fujii, Akira Mukai, Naoko Shibata, Shintaro Sato, Hiroshi Kiyono, Kazuyoshi Gotoh, Daisuke Motooka, Shota Nakamura, Tetsuya Iida, Masahiko Tsujii, Tetsuo Takehara

Inflammatory Bowel Diseases　Vol. 20　No. 5　p. 790-799　2014/05　Research paper (scientific journal)

Comprehensive metagenomic approach for detecting causative microorganisms in culture-negative infective endocarditis

Atsuko Imai, Kazuyoshi Gotoh, Yoshihiro Asano, Noriaki Yamada, Daisuke Motooka, Masaki Fukushima, Machiko Kanzaki, Tomohito Ohtani, Yasushi Sakata, Hiroyuki Nishi, Koichi Toda, Yoshiki Sawa, Issei Komuro, Toshihiro Horii, Tetsuya Iida, Shota Nakamura, Seiji Takashima

International Journal of Cardiology　Vol. 172　No. 2　p. E288-E289　2014/03/15　Research paper (scientific journal)

Allergic bronchopulmonary mycosis due to co-infection with Aspergillus fumigatus and Schizophyllum commune

Masafumi Seki, Hideaki Ohno, Kazuyoshi Gotoh, Daisuke Motooka, Shota Nakamura, Tetsuya Iida, Yoshitsugu Miyazaki, Kazunori Tomono

ID Cases　Vol. 1　No. 1　p. 5-8　2014/02　Research paper (scientific journal)

Dynamics of Fecal Microbiota in Bangladeshi Children

Kazuyoshi Gotoh, Daisuke Motooka, Shota Nakamura, Shirajum Monira, Muniral Alam, Tetsuya Iida

2014/02　Research paper (international conference proceedings)

Mutation accumulation in bacteria exposed to UV radiation

Atsushi Shibai, Saburo Tsuru, Bei Wen Ying, Daisuke Motooka, Kazuyoshi Gotoh, Shota Nakamura, Tetsuya Yomo

Artificial Life 14 - Proceedings of the 14th International Conference on the Synthesis and Simulation of Living Systems, ALIFE 2014　p. 757-758　2014　Research paper (international conference proceedings)

Allergic bronchopulmonary mycosis due to co-infection with Aspergillus fumigatus and Schizophyllum commune

Masafumi Seki, Hideaki Ohno, Kazuyoshi Gotoh, Daisuke Motooka, Shota Nakamura, Tetsuya Iida, Yoshitsugu Miyazaki, Kazunori Tomono

IDCases　Vol. 1　No. 1　p. 5-8　2014　Research paper (scientific journal)

Complete genome sequence of Ureaplasma parvum serovar 3 strain SV3F4, isolated in Japan

Heng Ning Wu, Yukiko Nakura, Daisuke Motooka, Shota Nakamura, Fumiko Nishiumi, Saki Ishino, Yasuhiro Kawai, Tatsuya Tanaka, Makoto Takeuchi, Masahiro Nakayama, Tomio Fujita, Itaru Yanagihara

Genome Announcements　Vol. 2　No. 3　2014　Research paper (scientific journal)

Generation of colonic IgA-secreting cells in the caecal patch

Kazunori Masahata, Eiji Umemoto, Hisako Kayama, Manato Kotani, Shota Nakamura, Takashi Kurakawa, Junichi Kikuta, Kazuyoshi Gotoh, Daisuke Motooka, Shintaro Sato, Tomonori Higuchi, Yoshihiro Baba, Tomohiro Kurosaki, Makoto Kinoshita, Yosuke Shimada, Taishi Kimura, Ryu Okumura, Akira Takeda, Masaru Tajima, Osamu Yoshie, Masahiro Fukuzawa, Hiroshi Kiyono, Sidonia Fagarasan, Tetsuya Iida, Masaru Ishii, Kiyoshi Takeda

Nature communications　Vol. 5　2014　Research paper (scientific journal)

Severe respiratory failure due to co-infection with human metapneumovirus and Streptococcus pneumoniae

Masafumi Seki, Hisao Yoshida, Kazuyoshi Gotoh, Nobuyuki Hamada, Daisuke Motooka, Shota Nakamura, Norihisa Yamamoto, Shigeto Hamaguchi, Yukihiro Akeda, Hiroshi Watanabe, Tetsuya Iida, Kazunori Tomono

Respiratory Medicine Case Reports　Vol. 12　p. 13-15　2014　Research paper (scientific journal)

A Database for Rapid Detection of Pathogens in Infectious Diseases

Daisuke Motooka, Kazuyoshi Gotoh, Shota Nakamura, Toshihiro Horii

2014/01　Research paper (international conference proceedings)

Conformational preferences of 4-chloroproline residues

Hae Sook Park, Byung Jin Byun, Daisuke Motooka, Kazuki Kawahara, Masamitsu Doi, Takashi Nakazawa, Yuji Kobayashi, Young Kee Kang

Biopolymers　Vol. 97　No. 8　p. 629-641　2012/08　Research paper (scientific journal)

Polymorphism of collagen triple helix revealed by ¹⁹F NMR of model peptide [Pro-4(R)-hydroxyprolyl-Gly]<inf>3</inf>-[Pro-4(R)-Fluoroprolyl- Gly]-[Pro-4(R)-Hydroxyprolyl-Gly]<inf>3</inf>

Kazuki Kawahara, Nobuaki Nemoto, Daisuke Motooka, Yoshinori Nishi, Masamitsu Doi, Susumu Uchiyama, Takashi Nakazawa, Yuji Nishiuchi, Takuya Yoshida, Tadayasu Ohkubo, Yuji Kobayashi

Journal of Physical Chemistry B　Vol. 116　No. 23　p. 6908-6915　2012/06/14　Research paper (scientific journal)

The triple helical structure and stability of collagen model peptide with 4(S)-hydroxyprolyl-Pro-Gly units.

Daisuke Motooka, Kazuki Kawahara, Shota Nakamura, Masamitsu Doi, Yoshinori Nishi, Yuji Nishiuchi, Young Kee Kang, Takashi Nakazawa, Susumu Uchiyama, Takuya Yoshida, Tadayasu Ohkubo, Yuji Kobayashi

Biopolymers　Vol. 98　No. 2　p. 111-121　2012　Research paper (scientific journal)

34 Structure-Function Study of Marinostatin, a Natural Ester-Linked Serine Protease Inhibitor(Oral Presentation)

Taichi Misako, Yamazaki Toshimasa, Kawahara Kazuki, Motooka Daisuke, Nakamura Shota, Teshima Tadashi, Ohkubo Tadayasu, Kobayashi Yuji, Nishiuchi Yuji

Symposium on the Chemistry of Natural Products, symposium papers　No. 53　p. 199-204　2011/09/02

Cloning, expression, crystallization and preliminary X-ray crystallographic analysis of a human condensin SMC2 hinge domain with short coiled coils

Kazuki Kawahara, Shota Nakamura, Yasuhiro Katsu, Daisuke Motooka, Yuki Hosokawa, Yukiko Kojima, Keiko Matsukawa, Hiroto Takinowaki, Susumu Uchiyama, Yuji Kobayashi, Kiichi Fukui, Tadayasu Ohkubo

Acta Crystallographica Section F: Structural Biology and Crystallization Communications　Vol. 66　No. 9　p. 1067-1070　2010/09　Research paper (scientific journal)

Structure-activity relationship of marinostatin, a serine protease inhibitor isolated from a marine organism

Misako Taichi, Tohimasa Yamazaki, Kazuki Kawahara, Daisuke Motooka, Shota Nakamura, Shusaku Harada, Tadashi Teshima, Tadayasu Ohkubo, Yuji Kobayashi, Yuji Nishiuchi

Journal of Peptide Science　Vol. 16　No. 7　p. 329-336　2010/07　Research paper (scientific journal)

Hyperstability and crystal structure of cytochrome c<inf>555</inf> from hyperthermophilic Aquifex aeolicus

Marii Obuchi, Kazuki Kawahara, Daisuke Motooka, Shota Nakamura, Masaru Yamanaka, Taku Takeda, Susumu Uchiyama, Yuji Kobayashi, Tadayasu Ohkubo, Yoshihiro Sambongi

Acta Crystallographica Section D: Biological Crystallography　Vol. 65　No. 8　p. 804-813　2009　Research paper (scientific journal)

F-19-NMR study of collagen model peptides containing 4(R)-fluoroproline

Kazuki Kawahara, Nobuaki Nemoto, Daisuke Motooka, Susumu Uchiyama, Masamitsu Doi, Yuji Nishiuchi, Takashi Nakazawa, Takuya Yoshida, Tadayasu Ohkubo, Yoshinori Nishi, Yuji Kobayashi

JOURNAL OF PEPTIDE SCIENCE　Vol. 14　No. 8　p. 175-175　2008/08

Synthesis and characterization of the collagen model peptides containing 4(S)-hydroxyproline

Motooka Daisuke, Kawahara Kazuki, Nakamura Shota, Uchiyama Susumu, Doi Masamitsu, Nishiuchi Yuji, Nakazawa Takashi, Ohkubo Tadayasu, Nishi Yoshinori, Kobayashi Yuji

JOURNAL OF PEPTIDE SCIENCE　Vol. 14　No. 8　p. 172-172　2008/08

Possible biological processes controlled by the circatidal clock in the mangrove cricket inferred from transcriptome analysis

Hiroki Takekata, Shin Ichiro Tachibana, Daisuke Motooka, Shota Nakamura, Shin G. Goto

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