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Umakoshi Hiroshi

馬越 大

Graduate School of Engineering Science Department of Materials Engineering Science, Professor

keyword Membranome,Bio-Inspired Chemical Engineering,Reaction and Sepavation Engineery,Bio-process Engineering,Bioengineering

Education

  • 1992/04 - 1997/03, Osaka University, Grad. Sch. of Engineering Science, Div. of Chemical Engineering
  • 1988/04 - 1992/03, Osaka University, Faculty of Engineering Science, Dept of Chemical Engineering

Research History

  • 2012/04 - Present, Osaka University, Div. of Chemical Engineering, Grad. Sch. of Engineering Science, Professor
  • 2007/04 - 2012/03, Osaka University, Div. of Chemical Engineering, Grad. Sch. of Engineering Science, Associate Professor
  • 2003/04 - 2007/03, Osaka University, Div. of Chemical Engineering, Grad. Sch. of Engineering Science, Associate Professor
  • 2000/11 - 2003/04, Osaka University, Div. of Chemical Engineering, Grad. Sch. of Engineering Science, Lecturer
  • 1998/10 - 2000/10, Osaka University, Div. of Chem. Engineering, Grad. Sch. of Engineering Science, Research Associate
  • 1997 - 1998, スウエーデン・ルンド大学・博士研究員
  • 1997 - 1998, Post Doc Researcher, Lund University, Sweden

Research Areas

  • Manufacturing technology (mechanical, electrical/electronic, chemical engineering), Applied biofunctional and bioprocess engineering
  • Manufacturing technology (mechanical, electrical/electronic, chemical engineering), Catalytic processes and resource chemistry
  • Manufacturing technology (mechanical, electrical/electronic, chemical engineering), Chemical reaction and process system engineering
  • Manufacturing technology (mechanical, electrical/electronic, chemical engineering), Transfer phenomena and unit operations
  • Nanotechnology/Materials, Biochemistry
  • Nanotechnology/Materials, Molecular biochemistry
  • Nanotechnology/Materials, Nanobioscience
  • Nanotechnology/Materials, Nanomaterials

Professional Memberships

  • 化学工学会 人材育成センター
  • 化学工学会 関西支部 高度分離研究会
  • 分離技術会
  • American Chemical Society
  • Protein Society
  • 日本生物工学会
  • 化学工学会

Papers

  • Recent developments of microcapsules and polymer particles for separation medium, K. Shiomori,H. Matsune,S. Kiyoyama,T. Takei,M. Yoshida,H. Umakoshi, Journal of Physics: Conference Series, Vol. 1763, No. 1, 2021/02/02
  • Systematic Characterization of Nanostructured Lipid Carriers from Cetyl Palmitate/Caprylic Triglyceride/Tween 80 Mixtures in an Aqueous Environment, Ni'Matul Izza,Keishi Suga,Yukihiro Okamoto,Nozomi Watanabe,Tham Thi Bui,Yusuf Wibisono,Cut Rifda Fadila,Hiroshi Umakoshi, Langmuir, 2021
  • Structure and properties characterization of amphiphilic dendrons modified lipid membrane, Jin Han,Yosuke Iimure,Yukihiro Okamoto,Keishi Suga,Hiroshi Umakoshi, Chemistry Letters, Vol. 50, No. 1, p. 187-190, 2021
  • Preparation of bilayer molecular assembly from fatty acid and detergent, Shogo Taguchi,Yuta Kimura,Yasuaki Tachibana,Takuji Yamamoto,Hiroshi Umakoshi, Kagaku Kogaku Ronbunshu, Vol. 47, No. 2, p. 51-56, 2021
  • Investigation of Quercetin interaction behaviors with lipid bilayers: Toward understanding its antioxidative effect within biomembrane, Jin Han,Misaki Amau,Yukihiro Okamoto,Keishi Suga,Hiroshi Umakoshi, Journal of Bioscience and Bioengineering, 2021
  • Characterization of pH-Responsive Self-Assembly Behaviors of Fatty Acid-Functionalized Prodrug, Jin Han,Keita Hayashi,Yukihiro Okamoto,Keishi Suga,Hiroshi Umakoshi, Biochemical Engineering Journal, Vol. 164, 2020/12/15
  • Changes Caused by Liposomes to the Belousov-Zhabotinsky Reaction, Michael S. Chern,Yukihiro Okamoto,Keishi Suga,Nozomi Watanabe,Hiroshi Umakoshi, Journal of Physical Chemistry B, Vol. 124, No. 44, p. 9862-9869, 2020/11/05
  • A novel method of vesicle preparation by simple dilution of bicelle solution, Shogo Taguchi,Bong Su Kang,Keishi Suga,Yukihiro Okamoto,Ho Sup Jung,Hiroshi Umakoshi, Biochemical Engineering Journal, Vol. 162, 2020/10/15
  • Site specific analysis of anionic lipid by membrane surface-enhanced raman spectroscopy with different sized gold nanoparticles, Miftah Faried,Seiya Ando,Keishi Suga,Yukihiro Okamoto,Hiroshi Umakoshi, Chemistry Letters, Vol. 49, No. 9, p. 1107-1110, 2020/06
  • Enzymatic hydrolysis of cellulose recovered from ionic liquid-salt aqueous two-phase system, Kazuhiko Tanimura,Keishi Suga,Yukihiro Okamoto,Hiroshi Umakoshi, Journal of Bioscience and Bioengineering, Vol. 129, No. 5, p. 624-631, 2020/05
  • Evaluation of Molecular Ordering in Bicelle Bilayer Membranes Based on Induced Circular Dichroism Spectra, Keishi Suga,Kazuki Kitagawa,Shogo Taguchi,Yukihiro Okamoto,Hiroshi Umakoshi, Langmuir, Vol. 36, No. 12, p. 3242-3250, 2020/03/31
  • The potential anticancer activity of 5-fluorouracil loaded in cellulose fibers isolated from rice straw, Mostafa Yusefi,Kamyar Shameli,Hossein Jahangirian,Sin Yeang Teow,Hiroshi Umakoshi,Bahram Saleh,Roshanak Rafiee-Moghaddam,Thomas J. Webster, International Journal of Nanomedicine, Vol. 15, p. 5417-5432, 2020
  • Effect of dehydrocholic acid conjugated with a hydrocarbon on a lipid bilayer composed of 1,2-dioleoyl-sn-glycero-3-phosphocholine, Keita Hayashi,Kazutoshi Morimoto,Toshiyuki Kamei,Eiko Mieda,Sosaku Ichikawa,Takashi Kuroiwa,Sakiko Fujita,Hidemi Nakamura,Hiroshi Umakoshi, Colloids and Surfaces B: Biointerfaces, Vol. 181, p. 58-65, 2019/09/01
  • Membrane Surface-Enhanced Raman Spectroscopy for Cholesterol-Modified Lipid Systems: Effect of Gold Nanoparticle Size, Miftah Faried,Keishi Suga,Yukihiro Okamoto,Kamyar Shameli,Mikio Miyake,Hiroshi Umakoshi, ACS Omega, Vol. 4, No. 9, p. 13687-13695, 2019/08/27
  • Melting-Temperature-Dependent Interactions of Ergosterol with Unsaturated and Saturated Lipids in Model Membranes, Tham Thi Bui,Keishi Suga,Tonya L. Kuhl,Hiroshi Umakoshi, Langmuir, Vol. 35, No. 32, p. 10640-10647, 2019/08/13
  • Characterization of Ionic Liquid Aqueous Two-Phase Systems: Phase Separation Behaviors and the Hydrophobicity Index between the Two Phases, Kazuhiko Tanimura,Misaki Amau,Ryosuke Kume,Keishi Suga,Yukihiro Okamoto,Hiroshi Umakoshi, Journal of Physical Chemistry B, Vol. 123, No. 27, p. 5866-5874, 2019/07/11
  • Potential Interaction Behavior of Lanosterol and Unsaturated Phosphocholine in Monolayer Membrane, Tham Thi Bui,Keishi Suga,Hiroshi Umakoshi, Membrane, Vol. 44, p. 199-203, 2019/07
  • Ergosterol-Induced Ordered Phase in Ternary Lipid Mixture Systems of Unsaturated and Saturated Phospholipid Membranes, Tham Thi Bui,Keishi Suga,Hiroshi Umakoshi, Journal of Physical Chemistry B, Vol. 123, No. 29, p. 6161-6168, 2019/07/01
  • Solvatochromic Modeling of Laurdan for Multiple Polarity Analysis of Dihydrosphingomyelin Bilayer, Nozomi Watanabe,Yuka Goto,Keishi Suga,Thomas K.M. Nyholm,J. Peter Slotte,Hiroshi Umakoshi, Biophysical Journal, Vol. 116, No. 5, p. 874-883, 2019/03/05
  • Aggregation of chlorophyll a induced in self-assembled membranes composed of DMPC and DHPC, Shogo Taguchi,Keishi Suga,Keita Hayashi,Makoto Yoshimoto,Yukihiro Okamoto,Hidemi Nakamura,Hiroshi Umakoshi, Colloids and Surfaces B: Biointerfaces, Vol. 175, p. 403-408, 2019/03/01
  • Functional hydration behavior: Interrelation between hydration and molecular properties at lipid membrane interfaces, Nozomi Watanabe,Keishi Suga,Hiroshi Umakoshi, Journal of Chemistry, Vol. 2019, 2019
  • Detection of L-Proline-Catalyzed Michael Addition Reaction in Model Biomembrane, Masanori Hirose,Shigenori Sugisaki,Keishi Suga,Hiroshi Umakoshi, Journal of Chemistry, Vol. 2019, 2019
  • Smart preparation of polydiacetylene hydrogel based on self-assembly of tricosadiynoic acid and 1-oleoylglycerol (monoolein), Keishi Suga,Yoko Otsuka,Kengo Yoshida,Hiroshi Umakoshi, Journal of Chemical Engineering of Japan, Vol. 52, No. 3, p. 311-316, 2019
  • Nanotechnology for food engineering: Biomembrane and nanocarriers, Pahn Shick Chang,Hiroshi Umakoshi,Hakjin Kim, Journal of Chemistry, Vol. 2019, 2019
  • Lipid-Surrounding Water Molecules Probed by Time-Resolved Emission Spectra of Laurdan, Nozomi Watanabe,Keishi Suga,J. Peter Slotte,Thomas K.M. Nyholm,Hiroshi Umakoshi, Langmuir, Vol. 35, No. 20, p. 6762-6770, 2019
  • Effective concentration of ionic liquids for enhanced saccharification of cellulose, Kazuhiko Tanimura,Yoshiko Ooe,Keishi Suga,Hiroshi Umakoshi, ChemEngineering, Vol. 2, No. 4, p. 1-8, 2018/12
  • Systematic characterization of dmpc/dhpc self-assemblies and their phase behaviors in aqueous solution, Shogo Taguchi,Keishi Suga,Keita Hayashi,Yukihiro Okamoto,Ho Sup Jung,Hidemi Nakamura,Hiroshi Umakoshi, Colloids and Interfaces, Vol. 2, No. 4, 2018/12
  • Design of Pyrene-Fatty Acid Conjugates for Real-Time Monitoring of Drug Delivery and Controllability of Drug Release, Keita Hayashi,Yuma Mitsuyoshi,Toshiyuki Kamei,Toshinori Shimanouchi,Keishi Suga,Yukihiro Okamoto,Hidemi Nakamura,Hiroshi Umakoshi, ACS Omega, American Chemical Society, Vol. 3, No. 3, p. 3572-3580, 2018/03/31
  • Characterization of DDAB/Cholesterol Vesicles and Its Comparison with Lipid/Cholesterol Vesicles, Iwasaki Fumihiko,Suga Keishi,Okamoto Yukihiro,Umakoshi Hiroshi, JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, Vol. 18, No. 3, p. 1989-1994, 2018/03
  • Gel-Phase-like Ordered Membrane Properties Observed in Dispersed Oleic Acid/1-Oleoylglycerol Self-Assemblies: Systematic Characterization Using Raman Spectroscopy and a Laurdan Fluorescent Probe, Keishi Suga,Yoko Otsuka,Yukihiro Okamoto,Hiroshi Umakoshi, Langmuir, American Chemical Society, Vol. 34, No. 5, p. 2081-2088, 2018/02/06
  • Solvatochromic Property in Lipid Bilayer Interphases Evaluated from the Deconvolution of Time Resolved Emission Spectrum of Laurdan, Watanabe Nozomi,Nyholm Thomas K. M,Slotte J. Peter,Suga Keishi,Umakoshi Hiroshi, BIOPHYSICAL JOURNAL, Vol. 114, No. 3, 2018/02/02
  • Preparation and characterization of poly-N-isopropylacrylamide cryogels containing liposomes and their adsorption properties of tryptophan, Yui Hiramure,Keishi Suga,Hiroshi Umakoshi,Jin Matsumoto,Koichiro Shiomori, Solvent Extraction Research and Development, Vol. 25, No. 1, p. 37-46, 2018
  • Hydrolase-like activity provided by zinc(Ii) and oleoyl-histidine at liposome membrane surface, Atsushi Tauchi,Keishi Suga,Hiroshi Umakoshi, Colloids and Interfaces, Vol. 2, No. 2, 2018
  • Liposome membranes assist the l-proline-catalyzed aldol reaction of acetone and p-nitrobenzaldehyde in water, Masanori Hirose,Shimpei Fujiwara,Takaaki Ishigami,Keishi Suga,Yukihiro Okamoto,Hiroshi Umakoshi, Chemistry Letters, Vol. 47, No. 7, p. 931-934, 2018
  • Direct Observation of Amyloid β Behavior at Phospholipid Membrane Constructed on Gold Nanoparticles, Keishi Suga,Ying Chen Lai,Miftah Faried,Hiroshi Umakoshi, International Journal of Analytical Chemistry, Vol. 2018, 2018
  • Comparison of Physicochemical Membrane Properties of Vesicles Modified with Guanidinium Derivatives, Nozomi Watanabe,Keishi Suga,Hiroshi Umakoshi, Journal of Physical Chemistry B, AMER CHEMICAL SOC, Vol. 121, No. 39, p. 9213-9222, 2017/10/05
  • A Novel Role of Vesicles as Templates for the Oxidation and Oligomerization of p-Aminodiphenylamine by Cytochrome c, Sandra Luginbühl,Fumihiko Iwasaki,Elizabeth Chirackal Varkey,Hiroshi Umakoshi,Peter Walde, Helvetica Chimica Acta, WILEY-V C H VERLAG GMBH, Vol. 100, No. 5, 2017/05
  • Tailor-made drug carrier: Comparison of formation-dependent physicochemical properties within self-assembled aggregates for an optimal drug carrier, Keita Hayashi,Hideka Iwai,Toshiyuki Kamei,Kaede Iwamoto,Toshinori Shimanouchi,Sakiko Fujita,Hidemi Nakamura,Hiroshi Umakoshi, Colloids and Surfaces B: Biointerfaces, ELSEVIER SCIENCE BV, Vol. 152, p. 269-276, 2017/04
  • Induction of Chiral Recognition with Lipid Nanodomains Produced by Polymerization, Yukihiro Okamoto,Yusuke Kishi,Keishi Suga,Hiroshi Umakoshi, Biomacromolecules, AMER CHEMICAL SOC, Vol. 18, No. 4, p. 1180-1188, 2017/04
  • Preferential Adsorption of l-Histidine onto DOPC/Sphingomyelin/3β-[N-(N′,N′-dimethylaminoethane)carbamoyl]cholesterol Liposomes in the Presence of Chiral Organic Acids, Keishi Suga,Atsushi Tauchi,Takaaki Ishigami,Yukihiro Okamoto,Hiroshi Umakoshi, Langmuir, AMER CHEMICAL SOC, Vol. 33, No. 15, p. 3831-3838, 2017/04
  • Multi-Level Characterization of the Membrane Properties of Resveratrol-Incorporated Liposomes, Jin Han,Keishi Suga,Keita Hayashi,Yukihiro Okamoto,Hiroshi Umakoshi, Journal of Physical Chemistry B, AMER CHEMICAL SOC, Vol. 121, No. 16, p. 4091-4098, 2017/04
  • Enantioselective C - C Bond Formation Enhanced by Self-Assembly of Achiral Surfactants, Fumihiko Iwasaki,Keishi Suga,Yukihiro Okamoto,Hiroshi Umakoshi, ACS Omega, American Chemical Society, Vol. 2, No. 4, p. 1447-1453, 2017/04
  • Adsorption behavior of propranolol on negatively-charged liposomes and its influence on membrane fluidity and polarity, Takaaki Ishigami,Michael Sun Chern,Keishi Suga,Yukihiro Okamoto,Hiroshi Umakoshi, Journal of Nanoscience and Nanotechnology, AMER SCIENTIFIC PUBLISHERS, Vol. 17, No. 3, p. 1721-1728, 2017/03/01
  • Fluorescent Probe Study of AOT Vesicle Membranes and Their Alteration upon Addition of Aniline or the Aniline Dimer p-Aminodiphenylamine (PADPA), Fumihiko Iwasaki,Sandra Luginbühl,Keishi Suga,Peter Walde,Hiroshi Umakoshi, Langmuir, AMER CHEMICAL SOC, Vol. 33, No. 8, p. 1984-1994, 2017/02/28
  • Liposomes Can Achieve Enantioselective C-C Bond Formation of an α-Amino Acid Derivative in Aqueous Media, Fumihiko Iwasaki,Keishi Suga,Yukihiro Okamoto,Hiroshi Umakoshi, ACS Omega, American Chemical Society, Vol. 2, No. 1, p. 91-97, 2017/01/31
  • Characterization of liposome membrane containing chlorophyll a molecules and its photosensitized functions, Shogo Taguchi,Keishi Suga,Keita Hayashi,Makoto Yoshimoto,Yukihiro Okamoto,Hidemi Nakamura,Hiroshi Umakoshi, Journal of Nanoscience and Nanotechnology, AMER SCIENTIFIC PUBLISHERS, Vol. 17, No. 7, p. 4888-4893, 2017
  • Development of time-course oxygen binding analysis for hemoglobin-based oxygen carriers, Yukihiro Okamoto,Shigenori Sugisaki,Keishi Suga,Hiroshi Umakoshi, Analytical Sciences, JAPAN SOC ANALYTICAL CHEMISTRY, Vol. 33, No. 8, p. 953-956, 2017
  • Reactive bienzyme systems fabricated through immobilization of biotinylated glucose oxidase and peroxidase molecules onto neutralized avidin-conjugated liposomes, Takeshi Ohtsu,Saki Shigenari,Makoto Yoshimoto,Hiroshi Umakoshi, Biochemical Engineering Journal, ELSEVIER SCIENCE BV, Vol. 125, p. 81-87, 2017
  • Liposomes modified with cardiolipin can act as a platform to regulate the potential flux of NADP<sup>+</sup>-dependent isocitrate dehydrogenase, Keishi Suga,Akari Hamasaki,Junpei Chinzaka,Hiroshi Umakoshi, Metabolic Engineering Communications, Elsevier, Vol. 3, p. 8-14, 2016/12/01
  • Characterization of Aqueous Oleic Acid/Oleate Dispersions by Fluorescent Probes and Raman Spectroscopy, Keishi Suga,Dai Kondo,Yoko Otsuka,Yukihiro Okamoto,Hiroshi Umakoshi, Langmuir, AMER CHEMICAL SOC, Vol. 32, No. 30, p. 7606-7612, 2016/08/02
  • Characterization of sorbitan surfactant-based vesicles at the molecular scale using NMR: Effect of acyl chain length vs. phospholipid composition, Keita Hayashi,Hideka Iwai,Toshiyuki Kamei,Ayako Kato,Yusuke Murata,Hidemi Nakamura,Hiroshi Umakoshi, Colloids and Surfaces B: Biointerfaces, ELSEVIER SCIENCE BV, Vol. 144, p. 33-37, 2016/08/01
  • Effect of Stearylguanidinium-Modified POPC Vesicles on the Melting Behavior of tRNA Molecules, Keishi Suga,Nozomi Watanabe,Hiroshi Umakoshi, Journal of Physical Chemistry B, AMER CHEMICAL SOC, Vol. 120, No. 25, p. 5662-5669, 2016/06/30
  • Roles of Sterol Derivatives in Regulating the Properties of Phospholipid Bilayer Systems, Tham Thi Bui,Keishi Suga,Hiroshi Umakoshi, Langmuir, AMER CHEMICAL SOC, Vol. 32, No. 24, p. 6176-6184, 2016/06/21
  • Effect of Boundary Edge in DOPC/DPPC/Cholesterol Liposomes on Acceleration of l -Histidine Preferential Adsorption, Takaaki Ishigami,Atsushi Tauchi,Keishi Suga,Hiroshi Umakoshi, Langmuir, AMER CHEMICAL SOC, Vol. 32, No. 24, p. 6011-6019, 2016/06/21
  • Quantitative Monitoring of Microphase Separation Behaviors in Cationic Liposomes Using HHC, DPH, and Laurdan: Estimation of the Local Electrostatic Potentials in Microdomains, Keishi Suga,Kei Akizaki,Hiroshi Umakoshi, Langmuir, AMER CHEMICAL SOC, Vol. 32, No. 15, p. 3630-3636, 2016/05/03
  • Bio-inspired membrane, Hiroshi Umakoshi, Kobunshi, Vol. 65, No. 4, p. 166-168, 2016/04
  • Chiral Selective Adsorption of Ibuprofen on a Liposome Membrane, Yukihiro Okamoto,Yusuke Kishi,Takaaki Ishigami,Keishi Suga,Hiroshi Umakoshi, Journal of Physical Chemistry B, AMER CHEMICAL SOC, Vol. 120, No. 10, p. 2790-2795, 2016/03/17
  • Electrophoretic separation method for membrane pore-forming proteins in multilayer lipid membranes, Yukihiro Okamoto,Yusuke Tsujimoto,Hiroshi Umakoshi, Electrophoresis, WILEY-BLACKWELL, Vol. 37, No. 5-6, p. 762-768, 2016/03/01
  • Liposome membrane can induce self-cleavage of RNA that models the core fragments of hammerhead ribozyme, Keishi Suga,Seishiro Tanaka,Hiroshi Umakoshi, European Biophysics Journal, SPRINGER, Vol. 45, No. 1, p. 55-62, 2016/01/01
  • Development of easy, harmless, and energy-saving water cleanup method based on self-flotation of hollow glass beads coated with fatty acids, Yukihiro Okamoto,Yu Mine,Daiki Wada,Hiroshi Umakoshi, Chemistry Letters, CHEMICAL SOC JAPAN, Vol. 45, No. 5, p. 544-546, 2016
  • In situ cell surface modification for surface-enhanced Raman analysis of cell membrane, Yukihiro Okamoto,Takumi Ikeda,Keishi Suga,Hiroshi Umakoshi, Chemistry Letters, CHEMICAL SOC JAPAN, Vol. 45, No. 6, p. 622-624, 2016
  • Homochiral oligomerization of L-histidine in the presence of liposome membranes, Takaaki Ishigami,Yoshinori Kaneko,Keishi Suga,Yukihiro Okamoto,Hiroshi Umakoshi, Colloid and Polymer Science, SPRINGER, Vol. 293, No. 12, p. 3649-3653, 2015/12/01
  • High performance optical resolution with liposome immobilized hydrogel, Takaaki Ishigami,Kazuma Sugita,Keishi Suga,Yukihiro Okamoto,Hiroshi Umakoshi, Colloids and Surfaces B: Biointerfaces, ELSEVIER SCIENCE BV, Vol. 136, p. 256-261, 2015/12/01
  • Liposome Membrane as a Platform for the l -Pro-Catalyzed Michael Addition of trans-β-Nitrostyrene and Acetone, Masanori Hirose,Takaaki Ishigami,Keishi Suga,Hiroshi Umakoshi, Langmuir, AMER CHEMICAL SOC, Vol. 31, No. 47, p. 12968-12974, 2015/11/08
  • Formation of lens-like vesicles induced via microphase separations on a sorbitan monoester membrane with different headgroups, Keita Hayashi,Hideka Iwai,Toshinori Shimanouchi,Hiroshi Umakoshi,Tomoyuki Iwasaki,Ayako Kato,Hidemi Nakamura, Colloids and Surfaces B: Biointerfaces, ELSEVIER SCIENCE BV, Vol. 135, p. 235-242, 2015/11/01
  • Chiral Recognition of l -Amino Acids on Liposomes Prepared with l -Phospholipid, Takaaki Ishigami,Keishi Suga,Hiroshi Umakoshi, ACS Applied Materials and Interfaces, AMER CHEMICAL SOC, Vol. 7, No. 38, p. 21065-21072, 2015/09/30
  • Pseudo-Interphase of Liposome Promotes 1,3-Dipolar Cycloaddition Reaction of Benzonitrile Oxide and N -Ethylmaleimide in Aqueous Solution, Fumihiko Iwasaki,Keishi Suga,Hiroshi Umakoshi, Journal of Physical Chemistry B, AMER CHEMICAL SOC, Vol. 119, No. 30, p. 9772-9779, 2015/07/30
  • Membrane surface-enhanced Raman spectroscopy for sensitive detection of molecular behavior of lipid assemblies, Keishi Suga,Tomohiro Yoshida,Haruyuki Ishii,Yukihiro Okamoto,Daisuke Nagao,Mikio Konno,Hiroshi Umakoshi, Analytical Chemistry, AMER CHEMICAL SOC, Vol. 87, No. 9, p. 4772-4780, 2015/05/05
  • Microfluidic platforms with monolithically integrated hierarchical apertures for the facile and rapid formation of cargo-carrying vesicles, Hyesung Cho,Junsoo Kim,Keishi Suga,Takaaki Ishigami,Hyunchul Park,Jung Won Bang,Soonmin Seo,Mansoo Choi,Pahn Shick Chang,Hiroshi Umakoshi,Ho Sup Jung,Kahp Yang Suh, Lab on a Chip, ROYAL SOC CHEMISTRY, Vol. 15, No. 2, p. 373-377, 2015/01/21
  • Partitioning of hydrophobic molecules to liposome membranes can induce variations in their micro-polarity and micro-viscosity, Fumihiko Iwasaki,Keishi Suga,Dai Kondo,Hiroshi Umakoshi, Solvent Extraction Research and Development, JAPAN ASSOC SOLVENT EXTRACTION, Vol. 22, No. 1, p. 79-85, 2015
  • Characterization of the physicochemical properties of phospholipid vesicles prepared in CO<inf>2</inf>/water systems at high pressure, Hidemi Nakamura,Shogo Taguchi,Keishi Suga,Keita Hayashi,Ho Sup Jung,Hiroshi Umakoshi, Biointerphases, AMER INST PHYSICS, Vol. 10, No. 3, p. 1-6, 2015
  • Investigation of Fatty Acid Ketohydrazone Modified Liposome's Properties as a Drug Carrier, Hayashi Keita,Kiriishi Madoka,Suga Keishi,Okamoto Yukihiro,Umakoshi Hiroshi, JOURNAL OF DRUG DELIVERY, 2015
  • Systematical characterization of phase behaviors and membrane properties of fatty acid/didecyldimethylammonium bromide vesicles, Keishi Suga,Tomoya Yokoi,Dai Kondo,Keita Hayashi,Seiichi Morita,Yukihiro Okamoto,Toshinori Shimanouchi,Hiroshi Umakoshi, Langmuir, AMER CHEMICAL SOC, Vol. 30, No. 43, p. 12721-12728, 2014/11/04
  • Emergent properties arising from the assembly of amphiphiles. Artificial vesicle membranes as reaction promoters and regulators, Peter Walde,Hiroshi Umakoshi,Pasquale Stano,Fabio Mavelli, Chemical Communications, ROYAL SOC CHEMISTRY, Vol. 50, No. 71, p. 10177-10197, 2014/08/07
  • Relationship between the mobility of phosphocholine headgroup and the protein-liposome interaction: A dielectric spectroscopic study, Toshinori Shimanouchi,Noriko Yoshimoto,Azusa Hiroiwa,Keiichi Nishiyama,Keita Hayashi,Hiroshi Umakoshi, Colloids and Surfaces B: Biointerfaces, ELSEVIER SCIENCE BV, Vol. 116, p. 343-350, 2014/04
  • Development of metal affinity-immobilized liposome chromatography and its basic characteristics, Hideto Nagami,Hiroshi Umakoshi,Takenori Kitaura,Gary Lee Thompson,Toshinori Shimanouchi,Ryoichi Kuboi, Biochemical Engineering Journal, ELSEVIER SCIENCE BV, Vol. 84, p. 66-73, 2014/03/15
  • Comparison of the interfacial properties of span 80 vesicle, w/o emulsions and liposomes, Keita Hayashi,Hiroshi Umakoshi,Toshinori Shimanouchi, Solvent Extraction Research and Development, Vol. 21, No. 2, p. 191-199, 2014
  • Membrane interaction between Span 80 vesicle and phospholipid vesicle (liposome): Span 80 vesicle can perturb and hemifuse with liposomal membrane, Keita Hayashi,Tsuyoshi Tatsui,Toshinori Shimanouchi,Hiroshi Umakoshi, Colloids and Surfaces B: Biointerfaces, Vol. 106, p. 258-264, 2013/06/01
  • Detection of nanosized ordered domains in DOPC/DPPC and DOPC/CH binary lipid mixture systems of large unilamellar vesicles using a TEMPO quenching method, Keishi Suga,Hiroshi Umakoshi, Langmuir, AMER CHEMICAL SOC, Vol. 29, No. 15, p. 4830-4838, 2013/04
  • Growth behavior of giant vesicles using the electroformation method: Effect of proteins on swelling and deformation, Toshinori Shimanouchi,Hiroshi Umakoshi,Ryoichi Kuboi, Journal of Colloid and Interface Science, ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 394, No. 1, p. 269-276, 2013/03/15
  • Membrane fusion mediated by phospholipase C under endosomal pH conditions, Toshinori Shimanouchi,Hidenori Kawasaki,Makoto Fuse,Hiroshi Umakoshi,Ryoichi Kuboi, Colloids and Surfaces B: Biointerfaces, Vol. 103, p. 75-83, 2013/03/01
  • Heterogeneous cationic liposomes modified with 3β-{N-[(N′, N ′-dimethylamino)ethyl]carbamoyl}cholesterol can induce partial conformational changes in messenger RNA and regulate translation in an escherichia coli cell-free translation system, Keishi Suga,Tomoyuki Tanabe,Hiroshi Umakoshi, Langmuir, AMER CHEMICAL SOC, Vol. 29, No. 6, p. 1899-1907, 2013/02/12
  • Growth behavior of Aβ protofibrils on liposome membranes and their membrane perturbation effect, Toshinori Shimanouchi,Keiichi Nishiyama,Azusa Hiroiwa,Huong Thi Vu,Nachi Kitaura,Hiroshi Umakoshi,Ryoichi Kuboi, Biochemical Engineering Journal, ELSEVIER SCIENCE SA, Vol. 71, p. 81-88, 2013/02/05
  • Effect of liposome membranes on disaggregation of amyloid β fibrils by dopamine, Huong Thi Vu,Toshinori Shimanouchi,Daisuke Ishikawa,Tadaharu Matsumoto,Hisashi Yagi,Yuji Goto,Hiroshi Umakoshi,Ryoichi Kuboi, Biochemical Engineering Journal, ELSEVIER SCIENCE SA, Vol. 71, p. 118-126, 2013/02/05
  • Enhanced cytotoxicity for colon 26 cells using doxorubicin-loaded sorbitan monooleate (Span 80) vesicles, Keita Hayashi,Tsuyoshi Tatsui,Toshinori Shimanouchi,Hiroshi Umakoshi, International Journal of Biological Sciences, IVYSPRING INT PUBL, Vol. 9, No. 2, p. 142-148, 2013/01/17
  • Oligolamellar vesicles for covalent immobilization and stabilization of d-amino acid oxidase, Makoto Yoshimoto,Miku Yamasaki,Masakazu Okamoto,Hiroshi Umakoshi,Ryoichi Kuboi, Enzyme and Microbial Technology, ELSEVIER SCIENCE INC, Vol. 52, No. 1, p. 13-19, 2013/01/10
  • Use Liposome as a Designable Platform for Molecular Recognition ~ from “Statistical Separation” to “Recognitive Separation”, Hiroshi Umakoshi,Keishi Suga, Solvent Extraction Research and Development, JAPAN ASSOC SOLVENT EXTRACTION, Vol. 20, p. 1-13, 2013
  • Comparison of Partitioning Behaviors of L-/D-Trp in Solvent-Water System and Liposome Membrane System, Takaaki Ishigami,Hiroshi Umakoshi, Solvent Extraction Research and Development, Vol. 20, p. 213-217, 2013
  • Modulation of yeast hexokinase on bio-inspired membranes, Hiroshi Umakoshi,Atsushi Nishida, Biochemical Engineering Journal, ELSEVIER SCIENCE SA, Vol. 69, p. 138-143, 2012/12/15
  • Secondary nucleation of Aβ fibrils on liposome membrane, Toshinori Shimanouchi,Nachi Kitaura,Ryo Onishi,Hiroshi Umakoshi,Ryoichi Kuboi, AIChE Journal, WILEY-BLACKWELL, Vol. 58, No. 12, p. 3625-3632, 2012/12
  • Hydrophobic properties of tRNA with varied conformations evaluated by an aqueous two-phase system, Keishi Suga,Hibiki Tomita,Seishiro Tanaka,Hiroshi Umakoshi, International Journal of Biological Sciences, IVYSPRING INT PUBL, Vol. 8, No. 8, p. 1188-1196, 2012/10/15
  • Formation of spherulitic amyloid β aggregate by anionic liposomes, Toshinori Shimanouchi,Naoya Shimauchi,Ryo Ohnishi,Nachi Kitaura,Hisashi Yagi,Yuji Goto,Hiroshi Umakoshi,Ryoichi Kuboi, Biochemical and Biophysical Research Communications, ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 426, No. 2, p. 165-171, 2012/09/21
  • Effect of copper (II) ion against elongation behavior of amyloid β fibrils on liposome membranes, T. Shimanouchi,R. Onishi,N. Kitaura,H. Umakoshi,R. Kuboi, Crystal Research and Technology, Vol. 47, No. 1, p. 101-108, 2012/01
  • Active Targeting to Osteosarcoma Cells and Apoptotic Cell Death Induction by the Novel LectinEucheuma serra Agglutinin Isolated from a Marine Red Alga., Hayashi Keita,Walde Peter,Miyazaki Tatsuhiko,Sakayama Kenshi,Nakamura Atsushi,Kameda Kenji,Masuda Seizo,Umakoshi Hiroshi,Kato Keiichi, Journal of drug delivery, Vol. 2012, 2012
  • Copper-mediated growth of amyloid β fibrils in the presence of oxidized and negatively charged liposomes, Toshinori Shimanouchi,Ryo Onishi,Nachi Kitaura,Hiroshi Umakoshi,Ryoichi Kuboi, Journal of Bioscience and Bioengineering, SOC BIOSCIENCE BIOENGINEERING JAPAN, Vol. 112, No. 6, p. 611-615, 2011/12
  • Relationship between the mobility of phosphocholine headgroups of liposomes and the hydrophobicity at the membrane interface: A characterization with spectrophotometric measurements, Toshinori Shimanouchi,Masashi Sasaki,Azusa Hiroiwa,Noriko Yoshimoto,Kazuya Miyagawa,Hiroshi Umakoshi,Ryoichi Kuboi, Colloids and Surfaces B: Biointerfaces, ELSEVIER SCIENCE BV, Vol. 88, No. 1, p. 221-230, 2011/11/01
  • Conformational change of single-stranded RNAs induced by liposome binding, Keishi Suga,Tomoyuki Tanabe,Hibiki Tomita,Toshinori Shimanouchi,Hiroshi Umakoshi, Nucleic Acids Research, OXFORD UNIV PRESS, Vol. 39, No. 20, p. 8891-8900, 2011/11
  • Span 80 vesicles have a morefluid, flexibleand"wet"surface than phospholipid liposomes., Hayashi Keita,Shimanouchi Toshinori,Kato Keiichi,Miyazaki Tatsuhiko,Nakamura Atsushi,Umakoshi Hiroshi, Colloids and surfaces. B, Biointerfaces, Vol. 87, No. 1, 2011/10
  • Span 80 vesicles have a more fluid, flexible and " wet" surface than phospholipid liposomes, Keita Hayashi,Toshinori Shimanouchi,Keiichi Kato,Tatsuhiko Miyazaki,Atsushi Nakamura,Hiroshi Umakoshi, Colloids and Surfaces B: Biointerfaces, ELSEVIER SCIENCE BV, Vol. 87, No. 1, p. 28-35, 2011/10/01
  • Oxidative stress can affect the gene silencing effect of DOTAP liposome in an In Vitro translation system, Hiroshi Umakoshi,Tomoyuki Tanabe,Keishi Suga,Huong Thi Bui,Toshinori Shimanouchi,Ryoichi Kuboi, International Journal of Biological Sciences, IVYSPRING INT PUBL, Vol. 7, No. 3, p. 253-260, 2011
  • Cationic liposome can interfere mRNA translation in an E. coli cell-free translation system, Huong Thi Bui,Hiroshi Umakoshi,Keishi Suga,Tomoyuki Tanabe,Kien Xuan Ngo,Toshinori Shimanouchi,Ryoichi Kuboi, BIOCHEMICAL ENGINEERING JOURNAL, ELSEVIER SCIENCE BV, Vol. 52, No. 1, p. 38-43, 2010/10
  • Catechol derivatives inhibit the fibril formation of amyloid-beta peptides, Vu Thi Huong,Toshinori Shimanouchi,Naoya Shimauchi,Hisashi Yagi,Hiroshi Umakoshi,Yuji Goto,Ryoichi Kuboi, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, SOC BIOSCIENCE BIOENGINEERING JAPAN, Vol. 109, No. 6, p. 629-634, 2010/06
  • A sensitive thermochemical detector with a new target droplet supply and immobilization process, M. Noda,M. Noda,T. Shimanouchi,T. Asai,K. Yamashita,K. Yamashita,M. Okuyama,H. Umakoshi,R. Kuboi, Sensors and Actuators, B: Chemical, Vol. 147, p. 337-342, 2010/05/18
  • Analysis of the 22-NBD-cholesterol transfer between liposome membranes and its relation to the intermembrane exchange of 25-hydroxycholesterol, Haruyuki Ishii,Toshinori Shimanouchi,Hiroshi Umakoshi,Peter Walde,Ryoichi Kuboi, COLLOIDS AND SURFACES B-BIOINTERFACES, ELSEVIER SCIENCE BV, Vol. 77, No. 1, p. 117-121, 2010/05
  • Development of liposome-based mimics of superoxide dismutase and peroxidase based on the "LIPOzyme" concept, Hiroshi Umakoshi,Kengo Morimoto,Naoto Yasuda,Toshinori Shimanouchi,Ryoichi Kuboi, JOURNAL OF BIOTECHNOLOGY, ELSEVIER SCIENCE BV, Vol. 147, No. 1, p. 59-63, 2010/05
  • Liposomes destabilize tRNA during heat stress, Keishi Suga,Hiroshi Umakoshi,Hibiki Tomita,Tomoyuki Tanabe,Toshinori Shimanouchi,Ryoichi Kuboi, BIOTECHNOLOGY JOURNAL, WILEY-V C H VERLAG GMBH, Vol. 5, No. 5, p. 526-529, 2010/05
  • Monitoring of membrane damages by dialysis treatment: Study with membrane chip analysis, Toshinori Shimanouchi,Ena Oyama,Huong Thi Vu,Haruyuki Ishii,Hiroshi Umakoshi,Ryoichi Kuboi, DESALINATION AND WATER TREATMENT, DESALINATION PUBL, Vol. 17, No. 1-3, p. 45-51, 2010/05
  • Preparation of superoxide dismutase LIPOzyme in hollow fiber membrane module, Hiroyuki Sugaya,Hiroshi Umakoshi,K. B. M. A. Fadzil,Le Quoc Tuan,Toshinori Shimanouchi,Ryoichi Kuboi, DESALINATION AND WATER TREATMENT, DESALINATION PUBL, Vol. 17, No. 1-3, p. 281-287, 2010/05
  • Chitosanase displayed on liposome can increase its activity and stability, Kien Xuan Ngo,Hiroshi Umakoshi,Toshinori Shimanouchi,Hiroyuki Sugaya,Ryoichi Kuboi, JOURNAL OF BIOTECHNOLOGY, ELSEVIER SCIENCE BV, Vol. 146, No. 3, p. 105-113, 2010/04
  • A beta/Cu-catalyzed oxidation of cholesterol in 1,2-dipalmitoyl phosphatidylcholine liposome membrane, Toshinori Shimanouchi,Makoto Tasaki,Huong Thi Vu,Haruyuki Ishii,Noriko Yoshimoto,Hiroshi Umakoshi,Ryoichi Kuboi, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, SOC BIOSCIENCE BIOENGINEERING JAPAN, Vol. 109, No. 2, p. 145-148, 2010/02
  • Characterization of Amyloid beta Fibrils with An Aqueous Two-Phase System: Implications of Fibril Formation, Toshinori Shimanouchi,Naoya Shimauchi,Keiichi Nishiyama,Huong Thi Vu,Hisashi Yagi,Yuji Goto,Hiroshi Umakoshi,Ryoichi Kuboi, SOLVENT EXTRACTION RESEARCH AND DEVELOPMENT-JAPAN, JAPAN ASSOC SOLVENT EXTRACTION, Vol. 17, p. 121-128, 2010
  • Analysis of interaction between liposome membranes induced by stress condition: Utilization of liposomes immobilized on indium tin oxide electrode, Haruyuki Ishii,Toshinori Shimanouchi,Hiroshi Umakoshi,Ryoichi Kuboi, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, SOC BIOSCIENCE BIOENGINEERING JAPAN, Vol. 108, No. 5, p. 425-428, 2009/11
  • Role of liposome on recognition and folding of oxidized and fragmented superoxide dismutase for its re-activation, Hiroshi Umakoshi,Le Quoc Tuan,Toshinori Shimanocuhi,Ryoichi Kuboi, BIOCHEMICAL ENGINEERING JOURNAL, ELSEVIER SCIENCE SA, Vol. 46, No. 3, p. 313-319, 2009/11
  • Membrane interference: Role of liposome on in vitro gene expression of GFP, Keishi Suga,Hiroshi Umakoshi,Huong Thi Bui,Tomoyuki Tanabe,Toshinori Shimanouchi,Ryoichi Kuboi, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, SOC BIOSCIENCE BIOENGINEERING JAPAN, Vol. 108, p. S102-S103, 2009/11
  • Disaggregation of catecholamine derivative-induced amyloid fibrils on biomembranes, Toshinori Shimanouchi,Huong Thi Vu,Hiroshi Umakoshi,Ryoichi Kuboi, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, SOC BIOSCIENCE BIOENGINEERING JAPAN, Vol. 108, p. S31-S32, 2009/11
  • Preparation of liposome immobilized membrane module and its application, Hiroshi Umakoshi,Hiroyuki Sugaya,Yuji Tohtake,Toshinori Shimanouchi,Ryoichi Kuboi, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, SOC BIOSCIENCE BIOENGINEERING JAPAN, Vol. 108, p. S65-S65, 2009/11
  • LIPOzyme: enzyme-like liposome?, Hiroshi Umakoshi,Le Quoc Tuan,Kengo Morimoto,Toshinori Shimanocuhi,Ryoichi Kuboi, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, SOC BIOSCIENCE BIOENGINEERING JAPAN, Vol. 108, p. S99-S99, 2009/11
  • Development of membrane chip system for study on membrane-protein interaction, Toshinori Shimanouchi,Haruyuki Ishii,Ena Oyama,Naoya Shimauchi,Hiroshi Umakoshi,Ryoichi Kuboi, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, SOC BIOSCIENCE BIOENGINEERING JAPAN, Vol. 108, p. S162-S163, 2009/11
  • Characterization of heat-induced interaction of neutral liposome with lipid membrane of Streptomyces griseus cell, Kien Xuan Ngo,Hiroshi Umakoshi,Toshinori Shimanouchi,Ryoichi Kuboi, COLLOIDS AND SURFACES B-BIOINTERFACES, ELSEVIER SCIENCE BV, Vol. 73, No. 2, p. 399-407, 2009/10
  • Negatively charged liposome as a potent inhibitor of post-translation during in vitro synthesis of green fluorescent protein, Huong Thi Bui,Hiroshi Umakoshi,Keishi Suga,Masato Nishida,Toshinori Shimanouchi,Ryoichi Kuboi, BIOCHEMICAL ENGINEERING JOURNAL, ELSEVIER SCIENCE SA, Vol. 46, No. 2, p. 154-160, 2009/10
  • Immobilization of intact liposomes on solid surfaces: A quartz crystal microbalance study, Thi Huong Vu,Toshinori Shimanouchi,Haruyuki Ishii,Hiroshi Umakoshi,Ryoichi Kuboi, JOURNAL OF COLLOID AND INTERFACE SCIENCE, ACADEMIC PRESS INC ELSEVIER SCIENCE, Vol. 336, No. 2, p. 902-907, 2009/08
  • Characterization of Hollow Fiber Immobilized Liposome Membrane by Using Aqueous Two-Phase Partitioning Systems, Hiroyuki Sugaya,Hiroshi Umakoshi,Yuji Tohtake,Toshinori Shimanouchi,Ryoichi Kuboi, SOLVENT EXTRACTION RESEARCH AND DEVELOPMENT-JAPAN, JAPAN ASSOC SOLVENT EXTRACTION, Vol. 16, p. 103-109, 2009
  • Characterization of Green Fluorescent Protein Using Aqueous Two-Phase Systems, Hiroshi Umakoshi,Masato Nishida,Keishi Suga,Huong Thi Bui,Toshinori Shimanouchi,Ryoichi Kuboi, SOLVENT EXTRACTION RESEARCH AND DEVELOPMENT-JAPAN, JAPAN ASSOC SOLVENT EXTRACTION, Vol. 16, p. 145-150, 2009
  • A Bio-Thermochemical Sensor of Microbolometer Immobilized Liposome for Detection of Causative Protein of Alzheimer's Disease, Amyloid Beta, Minoru Noda,Takeshi Asai,Kaoru Yamashita,Toshinori Shimanouchi,Hiroshi Umakoshi,Masanori Okuyama,Ryouichi Kuboi, 2009 IEEE SENSORS, VOLS 1-3, IEEE, p. 838-+, 2009
  • A Leakage Current Microsensor for Detection of Interaction between an Electrolyte-Entrapping Liposome and Protein, Minoru Noda,Takeshi Asai,Kaoru Yamashita,Toshinori Shimanouchi,Hiroshi Umakoshi,Masanori Okuyama,Ryouichi Kuboi, 2009 IEEE SENSORS, VOLS 1-3, IEEE, p. 1883-+, 2009
  • Characterization of surface properties of microbial transglutaminase using aqueous two-phase partitioning method, Hiroshi Umakoshi,Noriko Yoshimoto,Makoto Yoshimoto,Toshinori Shimanouchi,Ryoichi Kuboi, SOLVENT EXTRACTION RESEARCH AND DEVELOPMENT-JAPAN, JAPAN ASSOC SOLVENT EXTRACTION, Vol. 15, p. 111-115, 2008
  • Variation of surface properties of Streptomyces griseus cells after heat treatment with liposome, Kien Xuan Ngo,Hiroshi Umakoshi,Toshinori Shimanouchi,Ryoichi Kuboi, SOLVENT EXTRACTION RESEARCH AND DEVELOPMENT-JAPAN, JAPAN ASSOC SOLVENT EXTRACTION, Vol. 15, p. 133-137, 2008
  • Study on Stress-Mediated Behavior and Preparation of Giant Vesicles, Toshinori Shimanouchi,Hiroshi Umakoshi,Ryoichi Kuboi, Giant Vesicles: Perspectives in Supramolecular Chemistry, Vol. 6, p. 369-377, 2007/03/12
  • Analysis and separation of amyloid beta-peptides using aqueous two-phase systems under stress conditions - From aqueous two-phase system to liposome membrane system, Ryoichi Kuboi,Hiroshi Umakoshi, SOLVENT EXTRACTION RESEARCH AND DEVELOPMENT-JAPAN, JAPAN ASSOC SOLVENT EXTRACTION, Vol. 13, p. 9-21, 2006
  • Protein refolding using stimuli-responsive polymer-modified aqueous two-phase systems, Ryoichi Kuboi,Seiichi Morita,Hideyuki Ota,Hiroshi Umakoshi, Journal of Chromatography B: Biomedical Sciences and Applications, Vol. 743, No. 1-2, p. 215-223, 2000/06/23
  • Immobilized - Liposome Chromatography for Refolding and Purification of Protein, Makoto Yoshimoto,Toshinori Shimanouchi,Hiroshi Umakoshi,Ryoichi Kuboi, Journal of Chromatography B, Vol. 743, No. 1/2, p. 93-99, 2000/06/23
  • Stimuli - Responsive Separation of Proteins Using Immobilized - Liposome Chromatography, Toshinori Shimanouchi,Seiichi Morita,Hiroshi Umakoshi,Ryoichi Kuboi, Journal of Chromatography B, Vol. 743, No. 1/2, p. 85-91, 2000/06/23
  • Design of selective release and recovery of enzymes from Escherichia coli based on their location using nonionic detergent, triton X series, H Umakoshi,R Kuboi,Komasawa, I, FOOD AND BIOPRODUCTS PROCESSING, INST CHEMICAL ENGINEERS, Vol. 76, No. C3, p. 162-168, 1998/09
  • Enzyme release from heat-stressed cell membranes as a function of hydrophobicity evaluated by using aqueous two-phase systems, Hiroshi Umakoshi,Ryoichi Kuboi, Journal of Chromatography B: Biomedical Applications, Vol. 711, No. 1-2, p. 217-222, 1998/06/26
  • Selective Separation Process of Proteins Based on the Heat Stress-Induced Translocation across Phospholipid Membrane., Hiroshi Umakoshi,Toshinori Shimanouchi,Ryoichi Kuboi, Journal of Chromatography B, Vol. 711, No. 1/2, p. 111-116, 1998/06/26
  • OPTIMAL DISRUPTION METHODS FOR THE SELECTIVE RECOVERY OF BETA-GALACTOSIDASE FROM ESCHERICHIA-COLI, R KUBOI,H UMAKOSHI,N TAKAGI,KOMASAWA, I, JOURNAL OF FERMENTATION AND BIOENGINEERING, SOC FERMENTATION BIOENGINEERING, JAPAN, Vol. 79, No. 4, p. 335-341, 1995

Misc.

  • 生体内分子送達技術とその応用―ドラッグデリバリーシステムとその周辺技術―Membranome Therapy~デザイナー・ベシクル膜を活用する次世代DDS~, 林啓太,HAN Jin,馬越大, 化学工学, Vol. 83, No. 7, 2019/07/05
  • Chiral Recognition / Conversion on Liposome, 馬越大,菅恵嗣, 膜, Vol. 44, No. 2, 2019
  • Characterization of Molecular Behaviors on Phospholipid Membrane Surface based on Membrane Surface-Enhanced Raman Spectroscopy Method, 菅恵嗣,馬越大, 表面と真空, Vol. 62, No. 4, 2019
  • 吸着分離材のメゾスケールデザイン ソフトマター界面の秩序構造を活用するキラル医薬品/RNAの分離, 菅恵嗣,馬越大, 分離技術, Vol. 46, No. 6, 2016/11/30
  • 広がる膜分離の世界 Bio‐Inspired膜, 馬越大, 高分子, Vol. 65, No. 4, 2016/04/01
  • A “Membranome”―Based Approach toward “Bio‐Inspired Membrane”, 馬越大,島内寿徳,菅恵嗣, 膜, Vol. 37, No. 6, p. 264-269, 2012/11/01
  • 最先端・次世代の化学工学 Membranomeに基づく革新的バイオテクノロジー, 馬越大, 化学工学, Vol. 76, No. 4, p. 215-216, 2012/04/05
  • Amyloid Fibril Formation on Artificial Biomembranes, 島内寿徳,北浦奈知,馬越大,久保井亮一, 表面科学, Vol. 33, No. 1, 2012
  • 高付加価値結晶を得るプロセス操作の進化―プロセス化学と分離技術―生体膜界面を晶析場とするタンパク質のアミロイド形成/多形の制御~生体膜晶析~, 島内寿徳,北浦奈知,大西諒,馬越大,久保井亮一, 分離技術, Vol. 40, No. 6, p. 455-462, 2010/11/30
  • Development of LIPOzymes Based on Biomembrane Process Chemistry, Hiroshi Umakoshi,Toshinori Shimanouchi,Ryoichi Kuboi, Pharmaceutical Process Chemistry, Wiley-VCH, Vol. in press (2009), p. 421-441, 2010/10/05
  • Protein Recognition by Stressed Liposome~Toward Material Design Using Liposome as a Functional Unit~, 馬越大, 膜, Vol. 35, No. 5, p. 224-229, 2010/09/01
  • 脂質膜界面特性に基づくベシクル形成制御, 島内 寿徳,馬越 大,久保井 亮一,石井 治之,吉本 則子, 化学工学シンポジウムシリーズ, Vol. 81, p. 107-114, 2010
  • Oxidative/heat stress enhanced production of chitosanase from Streptomyces griseus cells through its interaction with liposome, Kien Xuan Ngo,Hiroshi Umakoshi,Haruyuki Ishii,Huong Thi Bui,Toshinori Shimanouchi,Ryoichi Kuboi, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, SOC BIOSCIENCE BIOENGINEERING JAPAN, Vol. 108, No. 6, p. 471-476, 2009/12
  • Oxidative/heat stress enhanced production of chitosanase from Streptomyces griseus cells through its interaction with liposome, Kien Xuan Ngo,Hiroshi Umakoshi,Haruyuki Ishii,Huong Thi Bui,Toshinori Shimanouchi,Ryoichi Kuboi, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, SOC BIOSCIENCE BIOENGINEERING JAPAN, Vol. 108, No. 6, p. 471-476, 2009/12
  • Charged liposome affects the translation and folding steps of in vitro expression of green fluorescent protein, Hiroshi Umakoshi,Keishi Suga,Huong Thi Bui,Masato Nishida,Toshinori Shimanouchi,Ryoichi Kuboi, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, SOC BIOSCIENCE BIOENGINEERING JAPAN, Vol. 108, No. 5, p. 450-454, 2009/11
  • Charged liposome affects the translation and folding steps of in vitro expression of green fluorescent protein, Hiroshi Umakoshi,Keishi Suga,Huong Thi Bui,Masato Nishida,Toshinori Shimanouchi,Ryoichi Kuboi, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, SOC BIOSCIENCE BIOENGINEERING JAPAN, Vol. 108, No. 5, p. 450-454, 2009/11
  • Polymethylthiophene/Nafion-modified glassy carbon electrode for selective detection of dopamine in the presence of ascorbic acid, Vu Thi Huong,Toshinori Shimanouchi,Do Phuc Quan,Hiroshi Umakoshi,Pham Hung Viet,Ryoichi Kuboi, JOURNAL OF APPLIED ELECTROCHEMISTRY, SPRINGER, Vol. 39, No. 10, p. 2035-2042, 2009/10
  • Polymethylthiophene/Nafion-modified glassy carbon electrode for selective detection of dopamine in the presence of ascorbic acid, Vu Thi Huong,Toshinori Shimanouchi,Do Phuc Quan,Hiroshi Umakoshi,Pham Hung Viet,Ryoichi Kuboi, JOURNAL OF APPLIED ELECTROCHEMISTRY, SPRINGER, Vol. 39, No. 10, p. 2035-2042, 2009/10
  • Calcein permeation across phosphatidylcholine bilayer membrane: Effects of membrane fluidity, liposome size, and immobilization, Toshinori Shimanouchi,Haruyuki Ishii,Noriko Yoshimoto,Hiroshi Umakoshi,Ryoichi Kuboi, COLLOIDS AND SURFACES B-BIOINTERFACES, ELSEVIER SCIENCE BV, Vol. 73, No. 1, p. 156-160, 2009/10
  • Engineering Science of LIPOzyme Process Chemistry, 馬越大, 膜, Vol. 34, No. 4, p. 179-185, 2009/07/01
  • Kinetic study on giant vesicle formation with electroformation method, Toshinori Shimanouchi,Hiroshi Umakoshi,Ryoichi Kuboi, Langmuir, Vol. 25, No. 9, p. 4835-4840, 2009/05/05
  • Kinetic Study on Giant Vesicle Formation with Electroformation Method, Toshinori Shimanouchi,Hiroshi Umakoshi,Ryoichi Kuboi, LANGMUIR, AMER CHEMICAL SOC, Vol. 25, No. 9, p. 4835-4840, 2009/05
  • メンブレン・ストレスバイオテクノロジーとアルツハイマー病の診断, 馬越大,島内寿徳,久保井亮一, 分離技術, Vol. 39, No. 2, p. 109-114, 2009/03/31
  • Liposome membrane can act like molecular and metal chaperones for oxidized and fragmented superoxide dismutase, Le Quoc Tuan,Hiroshi Umakoshi,Toshinori Shimanouchi,Ryoichi Kuboi, ENZYME AND MICROBIAL TECHNOLOGY, ELSEVIER SCIENCE INC, Vol. 44, No. 2, p. 101-106, 2009/02
  • Liposome membrane can act like molecular and metal chaperones for oxidized and fragmented superoxide dismutase, Le Quoc Tuan,Hiroshi Umakoshi,Toshinori Shimanouchi,Ryoichi Kuboi, ENZYME AND MICROBIAL TECHNOLOGY, ELSEVIER SCIENCE INC, Vol. 44, No. 2, p. 101-106, 2009/02
  • LIPOzyme: Basic and Its Possible Application, 2009
  • Cationic Liposome Inhibits Gene Expression in E.coli Cell-Free Translation System, Membrane, Vol. 34(3), 146-151 (2009), 2009
  • Medical Applications of Biointerface, 菅谷博之,遠武佑治,馬越大,久保井亮一,近藤科江,宮田完二郎,片岡一則, 表面科学, Vol. 30(4), 236-247 (2009), No. 4, 2009
  • リポソーム固定化カンチレバー型歪み抵抗センサの検討, 2009
  • リポソーム固定化カンチレバー型歪み抵抗センサの検討, 2009
  • Characterization of Polymer Hydrophobicity and Immobilized Liposome Membrane in Hollow Fiber Module, Solv. Extr. Res. Dev. Japan, Vol. 16, 98-104 (2009), 2009
  • Immobilization of Liposome on Solid Surface: A Quartz Microbalance Study, J. Colloid Surface Interf., Vol. in press (2009), 2009
  • Negatively-Charged Liposome is Potent Inhibitor of Protein Folding in Post-Translational Process of in vitro Gene Expression, Biochem. Eng. J., Vol. in press (2009), 2009
  • Calcein Permeation across Phospholipid Bilayer Membrane: Effect of Membrane Fluidity, Liposome Size and Immobilization, Colloid Surface B, Vol. in press (2009), 2009
  • Analysis of Interaction between Liposome Membranes Induced by Stress Condition, J. Biosci. Bioeng., Vol. in press (2009), 2009
  • LIPOzyme Process Chemistryの創成に関する基礎工学的研究, 膜, Vol. 35(4), in press (2009), 2009
  • Development of LIPOzymes Based on Biomembrane Process Chemistry, Pharmaceutical Process Chemistry (Ed. Shioiri, Izawa, and Kono-ike), Vol. in press (2009), 2009
  • Preparation of Hollow Fiber Immobilized Liposome Membrane, Membrane, Vol. 33, in press (2009), 2009
  • LIPOzyme: Basic and Its Possible Application, 2009
  • リポソーム固定化カンチレバー型歪み抵抗センサの検討, 2009
  • リポソーム固定化カンチレバー型歪み抵抗センサの検討, 2009
  • Cationic Liposome Inhibits Gene Expression in E.coli Cell-Free Translation System, Membrane, Vol. 34(3), 146-151 (2009), 2009
  • Characterization of Polymer Hydrophobicity and Immobilized Liposome Membrane in Hollow Fiber Module, Solv. Extr. Res. Dev. Japan, Vol. 16, 98-104 (2009), 2009
  • Immobilization of Liposome on Solid Surface: A Quartz Microbalance Study, J. Colloid Surface Interf., Vol. in press (2009), 2009
  • Negatively-Charged Liposome is Potent Inhibitor of Protein Folding in Post-Translational Process of in vitro Gene Expression, Biochem. Eng. J., Vol. in press (2009), 2009
  • Analysis of Interaction between Liposome Membranes Induced by Stress Condition, J. Biosci. Bioeng., Vol. in press (2009), 2009
  • LIPOzyme Process Chemistryの創成に関する基礎工学的研究, Membrane, Vol. 35(4), in press (2009), 2009
  • Preparation of Hollow Fiber Immobilized Liposome Membrane, Membrane, Vol. 33, in press (2009), 2009
  • Enhanced Release of Chitosanase from Streptomyces griseus through Direct Interaction of Liposome with Cell Membrane under Heat Stress, Kien Xuan Ngo,Hiroshi Umakoshi,Toshinori Shimanouchi,Huong Thi Bui,Ryoichi Kuboi, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, SOC BIOSCIENCE BIOENGINEERING JAPAN, Vol. 106, No. 6, p. 602-605, 2008/12
  • Enhanced Release of Chitosanase from Streptomyces griseus through Direct Interaction of Liposome with Cell Membrane under Heat Stress, Kien Xuan Ngo,Hiroshi Umakoshi,Toshinori Shimanouchi,Huong Thi Bui,Ryoichi Kuboi, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, SOC BIOSCIENCE BIOENGINEERING JAPAN, Vol. 106, No. 6, p. 602-605, 2008/12
  • Liposome membrane itself can affect gene expression in the Escherichia coli cell-free translation system, Huong Thi Bui,Hiroshi Urnakoshi,Kien Xuan Ngo,Masato Nishida,Toshinori Shimanouchi,Ryoichi Kuboi, LANGMUIR, AMER CHEMICAL SOC, Vol. 24, No. 19, p. 10537-10542, 2008/10
  • Liposome membrane itself can affect gene expression in the Escherichia coli cell-free translation system, Huong Thi Bui,Hiroshi Urnakoshi,Kien Xuan Ngo,Masato Nishida,Toshinori Shimanouchi,Ryoichi Kuboi, LANGMUIR, AMER CHEMICAL SOC, Vol. 24, No. 19, p. 10537-10542, 2008/10
  • Arsenic (V) induces a fluidization of algal cell and liposome membranes, Le Quoc Tuan,Tran Thi Thanh Huong,Pham Thi Anh Hong,Tomonori Kawakami,Toshinori Shimanouchi,Hiroshi Umakoshi,Ryoichi Kuboi, TOXICOLOGY IN VITRO, PERGAMON-ELSEVIER SCIENCE LTD, Vol. 22, No. 6, p. 1632-1638, 2008/09
  • Arsenic (V) induces a fluidization of algal cell and liposome membranes, Le Quoc Tuan,Tran Thi Thanh Huong,Pham Thi Anh Hong,Tomonori Kawakami,Toshinori Shimanouchi,Hiroshi Umakoshi,Ryoichi Kuboi, TOXICOLOGY IN VITRO, PERGAMON-ELSEVIER SCIENCE LTD, Vol. 22, No. 6, p. 1632-1638, 2008/09
  • Liposome modified with Mn-porphyrin complex can simultaneously induce antioxidative enzyme-like activity of both superoxide dismutase and peroxidase, Hiroshi Umakoshi,Kengo Morimoto,Yuji Ohama,Hideto Nagami,Toshinori Shimanouchi,Ryoichi Kuboi, LANGMUIR, AMER CHEMICAL SOC, Vol. 24, No. 9, p. 4451-4455, 2008/05
  • Liposome modified with Mn-porphyrin complex can simultaneously induce antioxidative enzyme-like activity of both superoxide dismutase and peroxidase, Hiroshi Umakoshi,Kengo Morimoto,Yuji Ohama,Hideto Nagami,Toshinori Shimanouchi,Ryoichi Kuboi, LANGMUIR, AMER CHEMICAL SOC, Vol. 24, No. 9, p. 4451-4455, 2008/05
  • Biomembrane Process Chemistry and Separation Technology~ Design and Development of Antioxidative LIPOzyme in One-Pot Based on Molecular Recognition Function of Liposome, 2008
  • LIPOzyme for Biomembrane Process Chemistry, 2008
  • Preparation and Properties of Antioxidative LIPOzyme, 2008
  • Cationic Liposome DOTAP can Knock-out mRNA and Silence Its Translation in E.coli Cell Free Translation System, 2008
  • Simple Ligand/Porphyrin Complex can Induce Both SOD and POD Activities Similar to Those of Metal-Ligand Complex, 2008
  • Superoxide Dismutase-like Activity of Dodecanoyl-His Modified Liposome, Membrane, Vol. 33(4), 180-187 (2008), 2008
  • Characterization of Surface Properties of Streptomyces griseus Cell after Heat Treatment with Liposome Using Aqueous Two-Phase Method, 2008
  • Separation and Analysis for Aβ Peptides Based on Recognition Function of Abnormal Biomembrane ~Membrane Chip Analysis Can Brighten a Potential Aspect of Alzheimer’s Disease~, 2008
  • LIPOzyme Design Based on Molecular Recognition Function of Liposome -Biomembrane Process Chemistry and Separation Technology-, 2008
  • Immobilized Liposome Chromatography/Bio-Membrane Module for Bioseparation and Bioreactor, 2008
  • Characterization of Oxidized and Fragmented Superoxide Dismutase Recruited on Liposome Surface, Membrane, Vol. 33(4), 173-179, 2008
  • LIPOzyme design based on molecular recognition function of liposome, 2008
  • Amyloid fibril formation on biomembrane: Analysis using membrane chip system, 2008
  • Cutting‐Edge of Membrane Stress Biotechnology, 久保井亮一,馬越大,島内寿徳, 膜, Vol. 33(6), 300-306 (2008), No. 6, p. 300-306, 2008
  • Liposome-recruited activity of oxidized and fragmented superoxide dismutase, Le Quoc Tuan,Hiroshi Umakoshi,Toshinori Shimanouchi,Ryoichi Kuboi, LANGMUIR, AMER CHEMICAL SOC, Vol. 24, No. 2, p. 350-354, 2008/01
  • Biomembrane Process Chemistry and Separation Technology~ Design and Development of Antioxidative LIPOzyme in One-Pot Based on Molecular Recognition Function of Liposome, 2008
  • LIPOzyme for Biomembrane Process Chemistry, 2008
  • Preparation and Properties of Antioxidative LIPOzyme, 2008
  • Cationic Liposome DOTAP can Knock-out mRNA and Silence Its Translation in E.coli Cell Free Translation System, 2008
  • Simple Ligand/Porphyrin Complex can Induce Both SOD and POD Activities Similar to Those of Metal-Ligand Complex, 2008
  • Immobilized Liposome Chromatography/Bio-Membrane Module for Bioseparation and Bioreactor, 2008
  • Characterization of Surface Properties of Streptomyces griseus Cell after Heat Treatment with Liposome Using Aqueous Two-Phase Method, 2008
  • Superoxide Dismutase-like Activity of Dodecanoyl-His Modified Liposome, Membrane, Vol. 33(4), 180-187 (2008), 2008
  • Characterization of Oxidized and Fragmented Superoxide Dismutase Recruited on Liposome Surface, Membrane, Vol. 33(4), 173-179, 2008
  • LIPOzyme Design Based on Molecular Recognition Function of Liposome -Biomembrane Process Chemistry and Separation Technology-, 2008
  • Separation and Analysis for Aβ Peptides Based on Recognition Function of Abnormal Biomembrane ~Membrane Chip Analysis Can Brighten a Potential Aspect of Alzheimer’s Disease~, 2008
  • LIPOzyme design based on molecular recognition function of liposome, 2008
  • Amyloid fibril formation on biomembrane: Analysis using membrane chip system, 2008
  • Liposome-recruited activity of oxidized and fragmented superoxide dismutase, Le Quoc Tuan,Hiroshi Umakoshi,Toshinori Shimanouchi,Ryoichi Kuboi, LANGMUIR, AMER CHEMICAL SOC, Vol. 24, No. 2, p. 350-354, 2008/01
  • Liposome-Assisted Refolding of Microbial Transglutaminase, Maku, Vol. 32(5), 287-293, 2007
  • 固定化リポソームセンサーと膜関連疾病への応用, 膜誌, Vol. 32(1), 32-39, 2007
  • Liposome-Assisted Refolding of Microbial Transglutaminase, Membrane, Vol. 32(5), 287-293, 2007
  • Immobilized Liosome Sensor and Its Application to Membrane-Related Diseases, 久保井亮一,馬越大,島内寿徳, MEMBRANE, Vol. 32, No. 1, p. 32-39, 2007/01/01
  • Fluorescence study on the domain formation of N-dodecanoyl-L-tryptophan within a liposome membrane, Kazuma Yasuhara,Toshinori Shimanouchi,Hiroshi Umakoshi,Ryoichi Kuboi, COLLOID AND POLYMER SCIENCE, SPRINGER, Vol. 285, No. 2, p. 239-243, 2006/11
  • Evaluation of temperature and guanidine hydrochloride-induced protein-liposome interactions by using immobilized liposome chromatography, Noriko Yoshimoto,Makoto Yoshimoto,Kazuma Yasuhara,Toshinori Shimanouchi,Hiroshi Umakoshi,Ryoichi Kuboi, Biochemical Engineering Journal, Vol. 29, No. 3, p. 174-181, 2006/04/15
  • Evaluation of temperature and guanidine hydrochloride-induced protein-liposome interactions by using immobilized liposome chromatography, N Yoshimoto,M Yoshimoto,K Yasuhara,T Shimanouchi,H Umakoshi,R Kuboi, BIOCHEMICAL ENGINEERING JOURNAL, ELSEVIER SCIENCE SA, Vol. 29, No. 3, p. 174-181, 2006/04
  • Evaluation of carboxylic acid-induced conformational transitions of β-lactoglobulin: Comparison of the alcohol effects on β-lactoglobulin, Bong-Kuk Lee,Toshinori Shimanouchi,Hiroshi Umakoshi,Ryoichi Kuboi, Biochemical Engineering Journal, Vol. 28, No. 1, p. 79-86, 2006/02
  • Evaluation of carboxylic acid-induced conformational transitions of beta-lactoglobulin: Comparison of the alcohol effects on beta-lactoglobulin, BK Lee,T Shimanouchi,H Umakoshi,R Kuboi, BIOCHEMICAL ENGINEERING JOURNAL, ELSEVIER SCIENCE SA, Vol. 28, No. 1, p. 79-86, 2006/02
  • Evaluation of carboxylic acid-induced conformational transitions of beta-lactoglobulin: Comparison of the alcohol effects on beta-lactoglobulin, BK Lee,T Shimanouchi,H Umakoshi,R Kuboi, BIOCHEMICAL ENGINEERING JOURNAL, ELSEVIER SCIENCE SA, Vol. 28, No. 1, p. 79-86, 2006/02
  • Membrane Stress Biotechnology, 2006
  • Design of stress-mediated bioprocess using liposome - recovery of chitosanase from Streptomyces griseus cells, 2006
  • Membrane Chip: Dynamic Analysis of Stressed Membrane-Membrane Interaction, 2006
  • Study on Interaction of Amyloid b-Peptide with Liposome, 2006
  • Stress-mediated preparation of liposomes incorporating membrane protein, 2006
  • LIPOzyme: design and development of artificial chaperone/enzyme liposome, 2006
  • Use LIPOzyme for Stress-Mediated Bioreactor and Bioseparation, 2006
  • Analysis and Separation of Amyloid b-Peptides Using Aqueous Two-Phase Systems under Stress Conditions ~From Aqueous Two-Phase System to Liposome Membrane System~, Solv. Extr. Res. Dev. Japan, Vol. in press, 2006
  • Evaluation of temperature and guanidine hydrochloride-induced protein-liposome interactions by using immobilized liposome chromatography, Vol. 29(3), 174-181, 2006
  • Evaluation of carboxylic acid-induced conformationla transitions of beta-lactoglobulin: Comparison of the alcohol effects on beta-lactoglobulin, Biochemical Engineering Journal, Vol. 28, 79-86, 2006
  • Analysis and Separation of Amyloid b-Peptides Using Aqueous Two-Phase Systems under Stress Conditions ~From Aqueous Two-Phase System to Liposome Membrane System~, Solv. Extr. Res. Dev. Japan, Vol. in press, 2006
  • Membrane Stress Biotechnology, 2006
  • Membrane Chip: Dynamic Analysis of Stressed Membrane-Membrane Interaction, 2006
  • Study on Interaction of Amyloid b-Peptide with Liposome, 2006
  • Stress-mediated preparation of liposomes incorporating membrane protein, 2006
  • Design of stress-mediated bioprocess using liposome - recovery of chitosanase from Streptomyces griseus cells, 2006
  • LIPOzyme: design and development of artificial chaperone/enzyme liposome, 2006
  • Use LIPOzyme for Stress-Mediated Bioreactor and Bioseparation, 2006
  • Analysis and Separation of Amyloid b-Peptides Using Aqueous Two-Phase Systems under Stress Conditions ~From Aqueous Two-Phase System to Liposome Membrane System~, Solv. Extr. Res. Dev. Japan, Vol. in press, 2006
  • Fluorescence study on the domain formation of N-dodecanoyl-L-tryptophan within a liposome membrane, Colloid and Polymer Science, Vol. 285, 239-243, 2006
  • Analysis and Separation of Amyloid b-Peptides Using Aqueous Two-Phase Systems under Stress Conditions ~From Aqueous Two-Phase System to Liposome Membrane System~, Solv. Extr. Res. Dev. Japan, Vol. in press, 2006
  • Evaluation of temperature and guanidine hydrochloride-induced protein-liposome interactions by using immobilized liposome chromatography, Biochemical Engineering Journal, Vol. 29(3), 174-181/,, 2006
  • プロセスケミストリーと分離技術 タンパク質の構造異常疾患におけるアミロイド線維の制御 ~メンブレン・ストレスバイオテクノロジーの視点から~, 島内寿徳,馬越大,久保井亮一, 分離技術, Vol. 35, No. 6, p. 391-396, 2005/11/30
  • 化学工学系2回生へのPBL教育に対するアウトカムズの持続的評価, 久保井亮一,島田弥,江頭靖幸,海老谷幸喜,紀ノ岡正博,高橋英明,佐藤博,馬越大,白石康浩,芝定孝,島内寿徳, 工学教育, Vol. 53, 52-57/,, No. 6, p. 52-57, 2005/11/20
  • Heat-enhanced production of chitosanase from Streptomyces griseus in the presence of liposome, KX Ngo,H Umakoshi,T Shimanouchi,HS Jung,S Morita,R Kuboi, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, SOC BIOSCIENCE BIOENGINEERING JAPAN, Vol. 100, No. 5, p. 495-501, 2005/11
  • Heat-enhanced production of chitosanase from Streptomyces griseus in the presence of liposome, KX Ngo,H Umakoshi,T Shimanouchi,HS Jung,S Morita,R Kuboi, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, SOC BIOSCIENCE BIOENGINEERING JAPAN, Vol. 100, No. 5, p. 495-501, 2005/11
  • Oxidation of cholesterol catalyzed by amyloid beta-peptide (A beta)-Cu complex on lipid membrane, N Yoshimoto,M Tasaki,T Shimanouchi,H Umakoshi,R Kuboi, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, SOC BIOSCIENCE BIOENGINEERING JAPAN, Vol. 100, No. 4, p. 455-459, 2005/10
  • Oxidation of cholesterol catalyzed by amyloid beta-peptide (A beta)-Cu complex on lipid membrane, N Yoshimoto,M Tasaki,T Shimanouchi,H Umakoshi,R Kuboi, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, SOC BIOSCIENCE BIOENGINEERING JAPAN, Vol. 100, No. 4, p. 455-459, 2005/10
  • テーマの自主設定に特に注力した化学工学系2回生へのPBL教育とその効果, 久保井亮一,島田弥,江頭靖幸,海老谷幸喜,紀ノ岡正博,高橋英明,佐藤博,馬越大,白石康浩,芝定孝, 工学教育, Vol. 53, No. 4, p. 18-22, 2005/07/20
  • Liposome-assisted activity of superoxide dismutase under oxidative stress, H Nagami,N Yoshimoto,H Umakoshi,T Shimanouchi,R Kuboi, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, SOC BIOSCIENCE BIOENGINEERING JAPAN, Vol. 99, No. 4, p. 423-428, 2005/04
  • Liposome-assisted activity of superoxide dismutase under oxidative stress, H Nagami,N Yoshimoto,H Umakoshi,T Shimanouchi,R Kuboi, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, SOC BIOSCIENCE BIOENGINEERING JAPAN, Vol. 99, No. 4, p. 423-428, 2005/04
  • Heat enhanced recovery of chitosanase from Streptomyces griceus using aqueous two-phase system, 2005
  • Metal affinity-immobilized liposome chromatography for detection of conformational change of peptide, 2005
  • Detection of Conformational Change of Protein Based on Protein-Liposome Interaction, 2005
  • Metal-affinity immobilized liposome chromatography to detect conformational change of peptide, 2005
  • Liposome-Assisted Activity of Superoxide Dismutase under Oxidative Stress, Journal of Bioscience and Bioengineering, Vol. vol. 99(4), 423-428, 2005
  • Oxidation of Cholesterol Catalyzed by Amyloid beta-Peptide (Abeta)-Cu Complex on Lipid Membrane, Journal of Bioscience and Bioengineering, Vol. vol 100(4), 455-459, 2005
  • Heat-Enhancd Production of Chitosanase from Streptomyces griceus in the Presence of Liposome, Journal of Bioscience and Bioengineering, Vol. vol.100(5), 495-501, 2005
  • 固定化リポソームクロマトグラフィー, リポソーム応用の新展開, Vol. 472-482, 2005
  • タンパク質の構造異常疾患におけるアミロイド線維の制御 ~メンブレン・ストレスバイオテクノロジーの視点から~, 分離技術会誌, Vol. vol.35(6), 391-396, 2005
  • 固定化リポソームクロマトグラフィー, リポソーム応用の新展開, Vol. 472-482, 2005
  • タンパク質の構造異常疾患におけるアミロイド線維の制御 〜メンブレン・ストレスバイオテクノロジーの視点から〜, 分離技術会誌, Vol. vol.35(6), 391-396/,, 2005
  • 第9章分析化学でのリポソーム 第1節固定化リポソームクロマトグラフィー 『リポソーム応用の新展開〜人工細胞の開発に向けて〜(監修:秋吉一成・辻井薫),編集:奥 直人・久保井 亮一・宝谷 紘一,NTS出版』, NTS出版, 2005
  • 第8章バイオエンジニアリングにおけるリポソーム 第10節リポソームの人工シャペロン機能 『リポソーム応用の新展開〜人工細胞の開発に向けて〜(監修:秋吉一成・辻井薫),編集:奥 直人・久保井 亮一・宝谷 紘一,NTS出版』, NTS出版, 2005
  • 第8章バイオエンジニアリングにおけるリポソーム 第3節リポソームの固定化 『リポソーム応用の新展開〜人工細胞の開発に向けて〜(監修:秋吉一成・辻井薫),編集:奥 直人・久保井 亮一・宝谷 紘一,NTS出版』, NTS出版, 2005
  • 第8章バイオエンジニアリングにおけるリポソーム 第5節人工酵素リポソーム 『リポソーム応用の新展開〜人工細胞の開発に向けて〜(監修:秋吉一成・辻井薫),編集:奥 直人・久保井 亮一・宝谷 紘一,NTS出版』, NTS出版, 2005
  • Metal affinity-immobilized liposome chromatography for detection of conformational change of peptide, 2005
  • Detection of Conformational Change of Protein Based on Protein-Liposome Interaction, 2005
  • Heat enhanced recovery of chitosanase from Streptomyces griceus using aqueous two-phase system, 2005
  • Metal-affinity immobilized liposome chromatography to detect conformational change of peptide, 2005
  • Liposome-assisted activity of superoxide dismutase under oxidative stress, Hideto Nagami,Noriko Yoshimoto,Hiroshi Umakoshi,Toshinori Shimanouchi,Ryoichi Kuboi, Journal of Bioscience and Bioengineering, Society of Fermentation and Bioengineering, Vol. 99, No. 4, p. 423-428, 2005
  • Oxidation of cholesterol catalyzed by amyloid β-peptide (Aβ)-Cu complex on lipid membrane, Noriko Yoshimoto,Makoto Tasaki,Toshinori Shimanouchi,Hiroshi Umakoshi,Ryoichi Kuboi, Journal of Bioscience and Bioengineering, Vol. 100, No. 4, p. 455-459, 2005
  • Heat-enhanced production of chitosanase from Streptomyces griseus in the presence of liposome, Kien Xuan Ngo,Hiroshi Umakoshi,Toshinori Shimanouchi,Ho Sup Jung,Seiichi Morita,Ryoichi Kuboi, Journal of Bioscience and Bioengineering, Vol. 100, No. 5, p. 495-501, 2005
  • Immobilized Liposome Chromatography, Vol. 472-482, 2005
  • Immobilized Liposome Chromatography, Vol. 472-482, 2005
  • Variable SOD-like activity of liposome modified with Mn(II)-porphyrin derivative complex, H Nagami,H Umakoshi,T Shimanouchi,R Kuboi, BIOCHEMICAL ENGINEERING JOURNAL, ELSEVIER SCIENCE SA, Vol. 21, No. 3, p. 221-227, 2004/11
  • Variable SOD-like activity of liposome modified with Mn(II)-porphyrin derivative complex, H Nagami,H Umakoshi,T Shimanouchi,R Kuboi, BIOCHEMICAL ENGINEERING JOURNAL, ELSEVIER SCIENCE SA, Vol. 21, No. 3, p. 221-227, 2004/11
  • 細胞膜のストレス応答の制御とその工学的応用, 久保井亮一,馬越大,永見英人,岸田学, 生物工学会誌, Vol. 82, No. 5, p. 201-204, 2004/05/25
  • Research and development which had large possibility . The membrane stress biotechnology . ~ The application of the drug delivery system to design and developmentThe application of the drug delivery system to design and development . ~, 久保井亮一,馬越大,島内寿徳, ケミカルエンジニヤリング, Vol. 49, No. 4, p. 255-260, 2004/04/01
  • Stress-Mediated Cross-Linking Reaction of Proteins on Liposome Membrane by Transglutaminase, 2004
  • Metal Affinity-Immobilized Liposome Chromatography for Stress Mediated Separation of Biomolecules, 2004
  • Characterization of Stress-Response Behavior of SOD/CAT on Liposome under Heat/Oxidative Stresses, 2004
  • Different Roles of Metal Ions Both in the Formation of Amyloid b-Fibri and Superoxide, 2004
  • Comparison of the extraction behavior of metal ions by metal affinity ligands in an organic-aqueous two-phase system and in a liposome system, H Nagami,H Umakoshi,T Shimanouchi,R Kuboi,Y Baba, SOLVENT EXTRACTION RESEARCH AND DEVELOPMENT-JAPAN, JAPAN ASSOC SOLVENT EXTRACTION, Vol. 11, p. 159-165, 2004
  • 細胞膜のストレス応答の制御とその工学的応用, 日本生物工学会誌,in press, 2004
  • Detection of protein conformation under stress conditions using liposomes as sensor materials, R Kuboi,T Shimanouchi,M Yoshimoto,H Umakoshi, SENSORS AND MATERIALS, MYU, SCIENTIFIC PUBLISHING DIVISION, Vol. 16, No. 5, p. 241-254, 2004
  • Different Roles of Metal Ions Both in the Formation of Amyloid b-Fibri and Superoxide, 2004
  • Metal Affinity-Immobilized Liposome Chromatography for Stress Mediated Separation of Biomolecules, 2004
  • Stress-Mediated Cross-Linking Reaction of Proteins on Liposome Membrane by Transglutaminase, 2004
  • Characterization of Stress-Response Behavior of SOD/CAT on Liposome under Heat/Oxidative Stresses, 2004
  • Comparison of the extraction behavior of metal ions by metal affinity ligands in an organic-aqueous two-phase system and in a liposome system, H Nagami,H Umakoshi,T Shimanouchi,R Kuboi,Y Baba, SOLVENT EXTRACTION RESEARCH AND DEVELOPMENT-JAPAN, JAPAN ASSOC SOLVENT EXTRACTION, Vol. 11, p. 159-165, 2004
  • 細胞膜のストレス応答の制御とその工学的応用, 2004
  • Detection of Protein Conformation under Stress Condition Using Liposome as Sensor Materials, 2004
  • 固定化リポソームクロマトグラフィーによる生理活性物質の分離・分析, 久保井亮一,馬越大,島内寿徳,森田誠一, ぶんせき, No. 11, p. 636-643, 2003/11/05
  • Artificial chaperone-assisted refolding of bovine carbonic anhydrase using molecular assemblies of stimuli-responsive polymers, N Yoshimoto,T Hashimoto,MM Felix,H Umakoshi,R Kuboi, BIOMACROMOLECULES, AMER CHEMICAL SOC, Vol. 4, No. 6, p. 1530-1538, 2003/11
  • Artificial chaperone-assisted refolding of bovine carbonic anhydrase using molecular assemblies of stimuli-responsive polymers, N Yoshimoto,T Hashimoto,MM Felix,H Umakoshi,R Kuboi, BIOMACROMOLECULES, AMER CHEMICAL SOC, Vol. 4, No. 6, p. 1530-1538, 2003/11
  • Artificial chaperone-assisted refolding of bovine carbonic anhydrase using molecular assemblies of stimuli-responsive polymers, N Yoshimoto,T Hashimoto,MM Felix,H Umakoshi,R Kuboi, BIOMACROMOLECULES, AMER CHEMICAL SOC, Vol. 4, No. 6, p. 1530-1538, 2003/11
  • Detection of a heat stress-mediated interaction between protein and phospholipid membrane using dielectric measurement, S Morita,T Shimanouchi,M Sasaki,H Umakoshi,R Kuboi, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, SOC BIOSCIENCE BIOENGINEERING JAPAN, Vol. 95, No. 3, p. 252-256, 2003/03
  • Detection of a heat stress-mediated interaction between protein and phospholipid membrane using dielectric measurement, S Morita,T Shimanouchi,M Sasaki,H Umakoshi,R Kuboi, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, SOC BIOSCIENCE BIOENGINEERING JAPAN, Vol. 95, No. 3, p. 252-256, 2003/03
  • Characterization of the surface properties of chitosanase under heat stress condition using aqueous two-phase systems and an immobilized-liposome sensor system, HS Jung,H Umakoshi,SY Son,T Shimanouchi,R Kuboi, SOLVENT EXTRACTION RESEARCH AND DEVELOPMENT-JAPAN, JAPAN ASSOC SOLVENT EXTRACTION, Vol. 10, p. 123-132, 2003
  • 固定化リポソームクロマトグラフィーよる生理活性物質の分離・分析, ぶんせき, 11, 636-642 (2003), Vol. 11, 636-642, 2003
  • Artificial Chaperone-Assisted Refololsy of Bovine carbonsic Auhyclvare using Molecular Assemblies of Stimuli-Responsive Polymers, Biomacromolecceles, Vol. in press, 2003
  • Characterization of the surface properties of chitosanase under heat stress condition using aqueous two-phase systems and an immobilized-liposome sensor system, HS Jung,H Umakoshi,SY Son,T Shimanouchi,R Kuboi, SOLVENT EXTRACTION RESEARCH AND DEVELOPMENT-JAPAN, JAPAN ASSOC SOLVENT EXTRACTION, Vol. 10, p. 123-132, 2003
  • 固定化リポソームクロマトグラフィーよる生理活性物質の分離・分析, Vol. 11, 636-642, 2003
  • 医薬品製造における晶析技術 タンパク質の構造異常化によるストレス誘導型アミロイドーシス, 島内寿徳,馬越大,久保井亮一, 分離技術, Vol. 32, No. 6, p. 347-351, 2002/11/30
  • Characterization and control of stimuli-induced membrane fusion of liposomes in the presence of proteins and stimuli responsive polymers, MM Felix,H Umakoshi,T Shimanouchi,M Yoshimoto,R Kuboi, BIOCHEMICAL ENGINEERING JOURNAL, ELSEVIER SCIENCE SA, Vol. 12, No. 1, p. 7-19, 2002/10
  • Characterization and control of stimuli-induced membrane fusion of liposomes in the presence of proteins and stimuli responsive polymers, MM Felix,H Umakoshi,T Shimanouchi,M Yoshimoto,R Kuboi, BIOCHEMICAL ENGINEERING JOURNAL, ELSEVIER SCIENCE SA, Vol. 12, No. 1, p. 7-19, 2002/10
  • ストレスバイオテクノロジーとマイクロプロセスへの展開 ストレス応答型バイオプロセスのためのストレスセンサの開発, JUNG H-S,島内寿徳,馬越大,久保井亮一,KIM K,桜井芳昭,夏川一輝, ケミカルエンジニヤリング, Vol. 47, No. 10, p. 752-755, 2002/10/01
  • Characterization of stimuli-induced membrane fusion of liposomes, MM Felix,T Shimanouchi,H Umakoshi,M Yoshimoto,R Kuboi, KAGAKU KOGAKU RONBUNSHU, SOC CHEMICAL ENG JAPAN, Vol. 28, No. 4, p. 481-484, 2002/07
  • Evaluation of interaction between liposome membranes induced by stimuli responsive polymer and protein, MM Felix,H Umakoshi,T Shimanouchi,M Yoshimoto,R Kuboi, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, SOC BIOSCIENCE BIOENGINEERING JAPAN, Vol. 93, No. 5, p. 498-501, 2002/05
  • Evaluation of interaction between liposome membranes induced by stimuli responsive polymer and protein, MM Felix,H Umakoshi,T Shimanouchi,M Yoshimoto,R Kuboi, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, SOC BIOSCIENCE BIOENGINEERING JAPAN, Vol. 93, No. 5, p. 498-501, 2002/05
  • ストレス応答型バイオプロセスのためのストレスセンサの開発, ケミカルエンジニヤリング,47, 10, 752-755, Vol. 47, 10, 752-755, 2002
  • タンパク質の構造異常化によるストレス誘導型アミロイドーシス, 分離技術, 32(6), 347-351 (2002), Vol. 32(6), 347-351, 2002
  • Monitoring of Protein-Liposome Interaction with Dielectric Dispersion Analysis, 2002
  • Monitoring of Surface Properties of Protein under Stress Conditions Using Array-Type Biosensor Based on Conductive Polymer, 2002
  • Cuaracterizatar and control of stimuli-Iuduecl Membrane Fusion of Liposomes in the Puesence of Pvocesus and Stimuli-Responsive Polymers, Biochem. Eng. J, Vol. 12(1), 7-19/,, 2002
  • Evaluation and Control of Interaction between Liposome Membrane Induced by Stimuli-Responsive Polymers and Pvocecns, J. Biosci. Bioeng., Vol. 93(5), 498-501/,, 2002
  • ストレス応答型バイオプロセスのためのストレスセンサの開発, Vol. 47, 10, 752-755, 2002
  • タンパク質の構造異常化によるストレス誘導型アミロイドーシス, Vol. 32(6), 347-351, 2002
  • 刺激誘導型リポソーム膜融合の評価と制御, Vol. 28, 4, 481-484, 2002
  • Cuaracterizatar and control of stimuli-Iuduecl Membrane Fusion of Liposomes in the Puesence of Pvocesus and Stimuli-Responsive Polymers, Biochem. Eng. J, Vol. 12(1), 7-19/,, 2002
  • Evaluation and Control of Interaction between Liposome Membrane Induced by Stimuli-Responsive Polymers and Pvocecns, J. Biosci. Bioeng., Vol. 93(5), 498-501/,, 2002
  • Control of surface properties of proteins by combined stimuli and protein separation in stimuli-responsive aqueous two-phase systems, H Umakoshi,R Kuboi,F Tjerneld, KAGAKU KOGAKU RONBUNSHU, SOC CHEMICAL ENG JAPAN, Vol. 27, No. 2, p. 197-204, 2001/03
  • Model process for separation based on unfolding and refolding of chymotrypsin inhibitor 2 in thermoseparating polymer two-phase systems, H Umakoshi,J Persson,M Kroon,HO Johansson,DE Otzen,R Kuboi,F Tjerneld, JOURNAL OF CHROMATOGRAPHY B, ELSEVIER SCIENCE BV, Vol. 743, No. 1-2, p. 13-19, 2000/06
  • Protein refolding using stimuli-responsive polymer-modified aqueous two-phase systems, R Kuboi,S Morita,H Ota,H Umakoshi, JOURNAL OF CHROMATOGRAPHY B, ELSEVIER SCIENCE BV, Vol. 743, No. 1-2, p. 215-223, 2000/06
  • Dielectric Response of Interaction between Protein and Lipid Membrane Induced by Heat Stress, J. Biosci. Bioeng., Vol. 90, No. 2, p. 157-162, 2000
  • Immobilized Liposome Chromatography for Refolding and Purification of Protein, J. Chromatogr. B, Vol. 743, No. 1/2, p. 93-99, 2000
  • Stimuli-Responsive Separation of Proteins Using Immobilized Liposome Chromatography, J. Chromatogr. B, Vol. 743, No. 1/2, p. 85-91, 2000
  • Dielectric Response of Cells and Vesicles and Its Utilization for Stress-Responsive Sensor, Seiichi Morita,Hiroshi Umakoshi,Ryoichi Kuboi, Biochemical Engineering and Bioseparation. Engineering, Vol. 70, p. 29-33, 1999/12
  • Conformationally changed cytochrome c-mediated fusion of enzyme- and substrate-containing liposomes, M Yoshimoto,P Walde,H Umakoshi,R Kuboi, BIOTECHNOLOGY PROGRESS, AMER CHEMICAL SOC, Vol. 15, No. 4, p. 689-696, 1999/07
  • Characterization and on-line monitoring of cell disruption and lysis using dielectric measurement, S Morita,H Umakoshi,R Kuboi, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, SOC BIOSCIENCE BIOENGINEERING JAPAN, Vol. 88, No. 1, p. 78-84, 1999/07
  • Study on Stress-Mediated Behavior and Preparation of Giant Vesicles, Wiley, 1999
  • Study on Stress-Mediated Behavior and Preparation of Giant Vesicles, Wiley, 1999
  • Separation process using ligand-modified aqueous two-phase system based on stress responsive behaviors of proteins, H Ota,K Yamahara,H Umakoshi,R Kuboi, SOLVENT EXTRACTION RESEARCH AND DEVELOPMENT-JAPAN, JAPAN ASSOC SOLVENT EXTRACTION, Vol. 6, p. 151-160, 1999
  • Utilization of cell response under heat, chemical, and combined stresses for selective recovery of cytoplasmic beta-galactosidase from Escherichia coli cells, H Umakoshi,Y Fukuta,R Kuboi, BIOTECHNOLOGY PROGRESS, AMER CHEMICAL SOC, Vol. 14, No. 6, p. 909-912, 1998/11
  • Enzyme release from heat-stressed cell membranes as a function of hydrophobicity evaluated by using aqueous two-phase systems, H Umakoshi,R Kuboi, JOURNAL OF CHROMATOGRAPHY B, ELSEVIER SCIENCE BV, Vol. 711, No. 1-2, p. 217-222, 1998/06
  • Model system for heat-induced translocation of cytoplasmic beta-galactosidase across phospholipid bilayer membrane, H Umakoshi,M Yoshimoto,T Shimanouchi,R Kuboi,Komasawa, I, BIOTECHNOLOGY PROGRESS, AMER CHEMICAL SOC, Vol. 14, No. 2, p. 218-226, 1998/03
  • Heat-induced translocation of cytoplasmic beta-galactosidase across inner membrane of Escherichia coli, H Umakoshi,R Kuboi,Komasawa, I,T Tsuchido,Y Matsumura, BIOTECHNOLOGY PROGRESS, AMER CHEMICAL SOC, Vol. 14, No. 2, p. 210-217, 1998/03
  • Selective Separation Process of Proteins Based on the Heat Stress-Induced Translocation across Phospholipid Membranes, J. Chromatogr. B, Vol. 711, No. 1/2, p. 111-116, 1998
  • Design of S lective Release of Intracellular Enzymes of Escherichia coli Based on Their Location using Nonionic Detergent, Triton X-100, Trans. Inst. Chem. Eng., Vol. 76, No. C3, p. 162-168, 1998
  • Topics of recent enzyme engineering. Aqueous two-phase system composite bioprocesses using stress response., 馬越大,久保井亮一,駒沢勲, ケミカルエンジニヤリング, Vol. 42, No. 5, p. 393-399, 1997/05
  • Control of partitioning of bacterial cells and characterization of their surface properties in aqueous two-phase systems, H Umakoshi,R Kuboi,Komasawa, I, JOURNAL OF FERMENTATION AND BIOENGINEERING, SOC FERMENTATION BIOENGINEERING, JAPAN, Vol. 84, No. 6, p. 572-578, 1997
  • Noticed topics of isolation technique. Development of bio production andseparation process using stress response function of the bio cell., 馬越大,久保井亮一,駒沢勲, ケミカルエンジニヤリング, Vol. 41, No. 8, p. 597-603, 1996/08
  • Extractive cultivation of recombinant Escherichia coli using aqueous two-phase systems for production and separation of intracellular heat shock proteins, H Umakoshi,K Yano,R Kuboi,Komasawa, I, BIOTECHNOLOGY PROGRESS, AMER CHEMICAL SOC, Vol. 12, No. 1, p. 51-56, 1996/01
  • Characterization of Partitioning Behaviors of Microorganisms and Their Homogenates in Aqueous Two-Phase Systems, Solv. Extr. Res. Dev. Japan, Vol. 3, p. 74-85, 1996
  • EXTRACTIVE CULTIVATION OF ESCHERICHIA-COLI USING POLY(ETHYLENE GLYCOL) PHOSPHATE AQUEOUS 2-PHASE SYSTEMS TO PRODUCE INTRACELLULAR BETA-GALACTOSIDASE, R KUBOI,H UMAKOSHI,KOMASAWA, I, BIOTECHNOLOGY PROGRESS, AMER CHEMICAL SOC, Vol. 11, No. 2, p. 202-207, 1995/03
  • OPTIMAL DISRUPTION METHODS FOR THE SELECTIVE RECOVERY OF BETA-GALACTOSIDASE FROM ESCHERICHIA-COLI, R KUBOI,H UMAKOSHI,N TAKAGI,KOMASAWA, I, JOURNAL OF FERMENTATION AND BIOENGINEERING, SOC FERMENTATION BIOENGINEERING, JAPAN, Vol. 79, No. 4, p. 335-341, 1995

Publications

  • メンブレン・ストレスバイオテクノロジー 〜薬物送達システムの設計と開発への応用〜, ケミカルエンジニヤリング,in press, 2004
  • メンブレン・ストレスバイオテクノロジー 〜薬物送達システムの設計と開発への応用〜, 2004
  • Study on Stress-Mediated Behavior and Preparation of Giant Vesicles, Giant Vesicles (ed. P. Walde and P. L. Luisi) John & Wiley (England), 1999

Works

  • ジャンクペプチド再機能化によるストレス応答方LIPOzymeリアクターの設計開発, 2010 -
  • アミロイド可溶化を指向するリポソーム膜上ペプチド断片 提示技術の研究, 2009 -
  • 体内ストレス解消を目指したリポソーム固定化膜モジュールの開発, 2009 -
  • ジャンクペプチド再機能化によるストレス応答方LIPOzymeリアクターの設計開発, 2009 -
  • バイオメンブレン・クロマトグラフィーの創成, 2009 -
  • Membranomics JSPS-SNSF日本-スイス二国間セミナー助成, 2008 -
  • ジャンクペプチド再機能化によるストレス応答型LIPOzymeリアクターの設計開発, 2008 -
  • JSPS-SNSF日本-スイス二国間セミナー助成, 2008 -
  • バイオメンブレン・クロマトグラフィーの創成, 2008 -
  • ストレス負荷バイオメンブレンによる遺伝子制御に関する研究, 2008 -
  • バイオメンブレン・クロマトグラフィーの創成, 2007 -
  • ストレス負荷バイオメンブレンによる遺伝子制御に関する研究, 2007 -
  • Bio-Inspiredナノケミカルファクトリーの創成(基礎工学部 未来ラボ), 2006 -
  • モデル生体膜チップを用いる細胞ストレスネットワークの解析とその応用, 2006 -
  • ストレス応答型人工酵素リポソームの設計開発, 2006 -
  • モデル生体膜チップを用いる細胞ストレスネットワークの解析とその応用, 2006 -
  • ストレス応答型人工酵素リポソームの設計開発, 2006 -
  • 次世代人工臓器を目指したストレス応答型リポソーム固定化分離膜・担体の開発, 2006 -
  • Bio-Inspiredナノケミカルファクトリーの創成(基礎工学部 未来ラボ), 2005 -
  • Bio-Inspiredナノケミカルファクトリーの創成(基礎工学部 未来ラボ), 2005 -
  • ストレス応答型人工酵素リポソームの設計開発, 2005 -
  • 次世代人工臓器を目指したストレス応答型リポソーム固定化分離膜・担体の開発, 2005 -
  • タンパク質の構造異常性の解析・診断システムの構築, 2004 -
  • Bio-Inspiredナノケミカルファクトリーの創成(基礎工学部 未来ラボ), 2004 -
  • 次世代人工臓器を目指したストレス応答型リポソーム固定化分離膜・担体の開発, 2004 -
  • 生体機能摸倣型マイクロバイオチップの設計・開発とプロテオーム解析への応用, 2003 -
  • タンパク質の構造異常性の解析・診断システムの構築, 2003 -
  • Bio-Inspiredナノケミカルファクトリーの創成(基礎工学部 未来ラボ), 2003 -
  • Bio-Inspiredナノケミカルファクトリーの創成(基礎工学部 未来ラボ), 2003 -
  • リポソームを用いたタンパク質リフォールディングシステムの開発, 2002 -
  • 生体機能摸倣型マイクロバイオチップの設計・開発とプロテオーム解析への応用, 2002 -
  • タンパク質の構造異常性に及ぼす人工シャペロンの共存効果, 2001 -
  • リポソームを用いたタンパク質リフォールディングシステムの開発, 2001 -
  • スマートポリマーナノ分子集合体を利用した自律応答型人工シャペロンの設計と応用, 2001 -
  • 環境ストレスセンサーの開発, 2000 -
  • リポソームを用いたタンパク質リフォールディングシステムの開発, 1999 -
  • 刺激応答性高分子集合体の設計・開発とバイオプロセスへの応用, 1999 -
  • ストレス応答型細胞・分子集合体の構造制御と利用プロセスの開発, 1997 -

Awards

  • The SCEJ Award for Outstanding Research Achievement, UMAKOSHI Hiroshi, Society of Chemical Engineers, Japan, 2019/12
  • Osaka University Award, UMAKOSHI Hiroshi, Osaka University, 2019/11
  • Membrane Society Award for Young Researcher, Hiroshi UMAKOSHI, Membrane Society, Japan, 2009/05
  • Invited Lecture "Engineering Science Approach to Create LIPOzyme Process Chemistry", 2009
  • 15th Young Investigator Award in Society of Membrane, Japan, 2009
  • Invited Lecture "Biomembrane Process Chemistry ~Challenge for Fusion of Separation Technology and Process Chemistry~", 2009
  • Invited Lecture LIPOzyme: Development of Artificial Enzyme Based on Membranome, 2008
  • Invited Lecture LIPOzyme ~Core Material for On-Chip Bioreactor and Stress Sensor~, 2006
  • Invited Lecture Antioxidative Function of Ab-Metal Complex on Liposome, 2005
  • Invited Lecture Development of Bioprocess Based on Membrane Stress Control, 2005
  • Invited Lecture Antioxidative Function of Ab-Cu Complex on Liposome, 2005
  • Outstanding Paper Award in APCChE2004 (SCEJ) (Oct.,2004, Kita-Kyushu), 2004
  • Invited Presentation "Application of Metal-Affinity Immobilized Liposome Chromatography", 2004
  • Outstanding Paper Award in APCChE2004 (SCEJ) (Oct.,2004, Kita-Kyushu), 2004
  • Award for Young Scientist of SCES, 2002
  • The SCEJ Award for Outstanding Young Engineer, Hiroshi UMAKOSHI, Society of Chemical Engineers, Japan, 2001

Committee Memberships

  • 化学工学会 関西支部 高度分離研究会, 幹事, 2004 -
  • 分離技術会, 分離技術会年会2005 実行委員会(事務局), 2004 -
  • 分離技術会, 分離技術会年会2005 International Session Chaiman, 2004 -
  • 化学工学会 人材育成センター, 理科教育委員会 委員, 2003 -