Clonal landscape of autoantibody-secreting plasmablasts in COVID-19 patients.

Shuhei Sakakibara, Yu-Chen Liu, Masakazu Ishikawa, Ryuya Edahiro, Yuya Shirai, Soichiro Haruna, Marwa Ali El Hussien, Zichang Xu, Songling Li, Yuta Yamaguchi, Teruaki Murakami, Takayoshi Morita, Yasuhiro Kato, Haruhiko Hirata, Yoshito Takeda, Fuminori Sugihara, Yoko Naito, Daisuke Motooka, Chao-Yuan Tsai, Chikako Ono, Yoshiharu Matsuura, James B Wing, Hisatake Matsumoto, Hiroshi Ogura, Masato Okada, Atsushi Kumanogoh, Yukinari Okada, Daron M Standley, Hitoshi Kikutani, Daisuke Okuzaki

Life science alliance　Vol. 7　No. 12　2024/12　Research paper (scientific journal)

網羅的生体情報の統合解析の課題 全血球トランスクリプトームと血漿プロテオームの関連性の評価

松本 寿健, 蛯原 健, 伊藤 弘, 瀬尾 茂人, 奥崎 大介, 織田 順

日本救急医学会雑誌　Vol. 35　No. 11　p. 877-877　2024/11

How can heatstroke damage the brain? A mini review

Kazuhiro Yoneda, Sanae Hosomi, Hiroshi Ito, Yuki Togami, Sayaka Oda, Hisatake Matsumoto, Junya Shimazaki, Hiroshi Ogura, Jun Oda

Frontiers in Neuroscience　Vol. 18　p. 1437216-1437216　2024/10/10　Research paper (scientific journal)

大規模言語モデルに基づく急性期補助診療モデル

松本 寿健, 蛯原 健, 舘野 丈太郎, 小倉 裕司, 織田 順

日本集中治療医学会雑誌　Vol. 31　No. Suppl.1　p. S982-S982　2024/09

Bacterial sepsis causes more dramatic pathogenetic changes in the Th1 pathway than does viral (COVID-19) sepsis: a prospective observational study of whole blood transcriptomes.

Arisa Muratsu, Sayaka Oda, Shinya Onishi, Jumpei Yoshimura, Hisatake Matsumoto, Yuki Togami, Yumi Mitsuyama, Hiroshi Ito, Daisuke Okuzaki, Hiroshi Ogura, Jun Oda

Virology journal　Vol. 21　No. 1　p. 190-190　2024/08/19　Research paper (scientific journal)

Atypical and non-classical CD45RBlo memory B cells are the majority of circulating SARS-CoV-2 specific B cells following mRNA vaccination or COVID-19.

David G Priest, Takeshi Ebihara, Janyerkye Tulyeu, Jonas N Søndergaard, Shuhei Sakakibara, Fuminori Sugihara, Shunichiro Nakao, Yuki Togami, Jumpei Yoshimura, Hiroshi Ito, Shinya Onishi, Arisa Muratsu, Yumi Mitsuyama, Hiroshi Ogura, Jun Oda, Daisuke Okusaki, Hisatake Matsumoto, James B Wing

Nature communications　Vol. 15　No. 1　p. 6811-6811　2024/08/09　Research paper (scientific journal)

Soluble T-cadherin secretion from endothelial cells is regulated via insulin/PI3K/Akt signalling.

Tomonori Okita, Shunbun Kita, Shiro Fukuda, Yuta Kondo, Taka-Aki Sakaue, Masahito Iioka, Keita Fukuoka, Keitaro Kawada, Hirofumi Nagao, Yoshinari Obata, Yuya Fujishima, Takeshi Ebihara, Hisatake Matsumoto, Satoshi Nakagawa, Tadashi Kimura, Hitoshi Nishizawa, Iichiro Shimomura

Biochemical and biophysical research communications　Vol. 732　p. 150403-150403　2024/07/14　Research paper (scientific journal)

Predictive biomarkers of COVID-19 prognosis identified in Bangladesh patients and validated in Japanese cohorts.

Kazuko Uno, Abu Hasan, Emi E Nakayama, Rummana Rahim, Hiromasa Harada, Mitsunori Kaneko, Shoji Hashimoto, Toshio Tanaka, Hisatake Matsumoto, Hitoshi Fujimiya, Tatsuo Shioda, Mizanur Rahman, Kazuyuki Yoshizaki

Scientific reports　Vol. 14　No. 1　p. 12713-12713　2024/06/03　Research paper (scientific journal)

Threonine phosphorylation of STAT1 restricts interferon signaling and promotes innate inflammatory responses.

Hozaifa Metwally, Maha M Elbrashy, Tatsuhiko Ozawa, Kazuki Okuyama, Jason T White, Janyerkye Tulyeu, Jonas Nørskov Søndergaard, James Badger Wing, Arisa Muratsu, Hisatake Matsumoto, Masahito Ikawa, Hiroyuki Kishi, Ichiro Taniuchi, Tadamitsu Kishimoto

Proceedings of the National Academy of Sciences of the United States of America　Vol. 121　No. 17　2024/04/23　Research paper (scientific journal)

Plasma Proteomics Profile-Based Comparison of Torso Versus Brain Injury: A Prospective Cohort Study.

Jotaro Tachino, Yuki Togami, Hisatake Matsumoto, Tsunehiro Matsubara, Shigeto Seno, Hiroshi Ogura, Jun Oda

The journal of trauma and acute care surgery　Vol. 97　No. 4　p. 557-565　2024/04/10　Research paper (scientific journal)

Association between tranexamic acid administration and mortality based on the trauma phenotype: a retrospective analysis of a nationwide trauma registry in Japan.

Jotaro Tachino, Shigeto Seno, Hisatake Matsumoto, Tetsuhisa Kitamura, Atsushi Hirayama, Shunichiro Nakao, Yusuke Katayama, Hiroshi Ogura, Jun Oda

Critical care (London, England)　Vol. 28　No. 1　p. 89-89　2024/03/19　Research paper (scientific journal)

Longitudinal whole blood transcriptome analysis of a septic shock patient with secondary hemophagocytic syndrome.

Risei Fujimoto, Sayaka Oda, Hisatake Matsumoto, Shunichiro Nakao, Kentaro Shimizu, Daisuke Okuzaki, Jun Oda

QJM : monthly journal of the Association of Physicians　2024/03/09　Research paper (scientific journal)

Study of Biomarkers in Saliva as Indicators for Diagnosis of Sports Related Concussion and Return to Play

Nakamura Youhei, Matsumoto Hisatake, Togami Yuki, Okuzaki Daisuke, Oda Jun

DESCENTE SPORTS SCIENCE　Vol. 45　p. 84-93　2024/02/22

Full-Length Nanopore Sequencing of Circular Rna Landscape in Peripheral Blood Cells Following Sequential Bnt162b2 Mrna Vaccination

Yu-Chen Liu, Masakazu Ishikawa, Shuhei Sakakibara, Mohamad Al Kadi, D. Motooka, Yoko Naito, Shingo Ito, Yuko Imamura, Hisatake Matsumoto, Fuminori Sugihara, Haruhiko Hirata, Hiroshi Ogura, D. Okuzaki

Gene　Vol. 933　p. 148971-148971　2024　Research paper (scientific journal)

Analysis of comprehensive biomolecules in critically ill patients via bioinformatics technologies.

Hisatake Matsumoto, Hiroshi Ogura, Jun Oda

Acute medicine & surgery　Vol. 11　No. 1　2024　Research paper (scientific journal)

T cell dysfunction in elderly ARDS patients based on miRNA and mRNA integration analysis.

Yumi Mitsuyama, Hisatake Matsumoto, Yuki Togami, Sayaka Oda, Shinya Onishi, Jumpei Yoshimura, Arisa Murtatsu, Hiroshi Ito, Hiroshi Ogura, Daisuke Okuzaki, Jun Oda

Frontiers in immunology　Vol. 15　p. 1368446-1368446　2024　Research paper (scientific journal)

広範囲熱傷患者におけるプロテオミクス解析 GDF-15と関連パスウェイ

大西 伸也, 蛯原 健, 松本 寿健, 杉原 文徳, 大須賀 章倫, 小倉 裕司, 織田 順

日本救急医学会雑誌　Vol. 34　No. 12　p. 752-752　2023/12

血漿プロテオミクスプロファイルによる体幹部外傷と外傷性脳損傷の比較 前向きコホート研究

舘野 丈太郎, 松本 寿健, 戸上 由貴, 松原 庸博, 瀬尾 茂人, 小倉 裕司, 織田 順

日本救急医学会雑誌　Vol. 34　No. 12　p. 641-641　2023/12

頭部外傷後てんかん発作に関連するプロテオーム解析

中村 洋平, 舘野 丈太郎, 松本 寿健, 小倉 裕司, 織田 順

日本救急医学会雑誌　Vol. 34　No. 12　p. 740-740　2023/12

Classification of patients with COVID-19 by blood RNA endotype: a prospective cohort study.

Jumpei Yoshimura, Yuki Togami, Takeshi Ebihara, Hisatake Matsumoto, Yumi Mitsuyama, Fuminori Sugihara, Haruhiko Hirata, Daisuke Okuzaki, Hiroshi Ogura

Microbiology spectrum　Vol. 11　No. 6　2023/11/15　Research paper (scientific journal)

Association between circ_0004365 and cisplatin resistance in esophageal squamous cell carcinoma.

Moyuru Yamada, Koji Tanaka, Kenichi Yamamoto, Hisatake Matsumoto, Makoto Yamasaki, Kotaro Yamashita, Tomoki Makino, Takuro Saito, Kazuyoshi Yamamoto, Tsuyoshi Takahashi, Yukinori Kurokawa, Kiyokazu Nakajima, Yukinori Okada, Hidetoshi Eguchi, Yuichiro Doki

Oncology letters　Vol. 26　No. 5　p. 467-467　2023/11　Research paper (scientific journal)

Complement factor D targeting protects endotheliopathy in organoid and monkey models of COVID-19.

Eri Kawakami, Norikazu Saiki, Yosuke Yoneyama, Chiharu Moriya, Mari Maezawa, Shuntaro Kawamura, Akiko Kinebuchi, Tamaki Kono, Masaaki Funata, Ayaka Sakoda, Shigeru Kondo, Takeshi Ebihara, Hisatake Matsumoto, Yuki Togami, Hiroshi Ogura, Fuminori Sugihara, Daisuke Okuzaki, Takashi Kojima, Sayaka Deguchi, Sebastien Vallee, Susan McQuade, Rizwana Islam, Madhusudan Natarajan, Hirohito Ishigaki, Misako Nakayama, Cong Thanh Nguyen, Yoshinori Kitagawa, Yunheng Wu, Kensaku Mori, Takayuki Hishiki, Tomohiko Takasaki, Yasushi Itoh, Kazuo Takayama, Yasunori Nio, Takanori Takebe

Cell stem cell　Vol. 30　No. 10　p. 1315-1330　2023/10/05　Research paper (scientific journal)

Importance of microRNAs by mRNA-microRNA integration analysis in acute ischemic stroke patients

Hideaki Kanki, Hisatake Matsumoto, Yuki Togami, Daisuke Okuzaki, Hiroshi Ogura, Tsutomu Sasaki, Hideki Mochizuki

Journal of Stroke and Cerebrovascular Diseases　Vol. 32　No. 9　p. 107277-107277　2023/09　Research paper (scientific journal)

Combination of HBA1, TTR, and SERPINF2 in plasma defines phenotype correlated with severe burn outcome

Shinya Onishi, Hisatake Matsumoto, Fuminori Sugihara, Takeshi Ebihara, Hiroshi Matsuura, Akinori Osuka, Daisuke Okuzaki, Hiroshi Ogura, Jun Oda

iScience　Vol. 26　No. 8　p. 107271-107271　2023/08/18　Research paper (scientific journal)

Ultrasound stimulation of the vagal nerve improves acute septic encephalopathy in mice

Yukio Imamura, Hisatake Matsumoto, Jun Imamura, Naoya Matsumoto, Kazuma Yamakawa, Nao Yoshikawa, Yuki Murakami, Satoko Mitani, Junichiro Nakagawa, Tomoki Yamada, Hiroshi Ogura, Jun Oda, Takeshi Shimazu

Frontiers in Neuroscience　Vol. 17　p. 1211608-1211608　2023/07/17　Research paper (scientific journal)

Whole-blood ribonucleic acid sequencing analysis in methemoglobinemia: a case report.

Chikai Mitsuhara, Yuki Togami, Tomoya Hirose, Shunichiro Nakao, Hiroshi Ito, Hisatake Matsumoto, Hiroshi Ogura, Daisuke Okuzaki, Jun Oda

Journal of medical case reports　Vol. 17　No. 1　p. 238-238　2023/06/10　Research paper (scientific journal)

機械学習による新規外傷フェノタイプの同定とプロテオーム解析を用いた病態考察

舘野 丈太郎, 松本 寿健, 杉原 文徳, 瀬尾 茂人, 奥崎 大介, 北村 哲久, 小向 翔, 木戸 善之, 兒嶋 嵩, 戸上 由貴, 片山 祐介, 中川 雄公, 小倉 裕司, 織田 順

日本集中治療医学会雑誌　Vol. 30　No. Suppl.1　p. S456-S456　2023/06

Pulmonary microbiota in the lower respiratory tract of ARDS patients

光山裕美, 清水健太郎, 松本寿健, 小倉裕司, 織田順

日本集中治療医学会学術集会(Web)　Vol. 30　No. Suppl.1　p. S417-S417　2023/06

Single-cell RNA-seq analysis identifies distinct myeloid cells in a case with encephalitis temporally associated with COVID-19 vaccination

Masakazu Ishikawa, Yuki Shimada, Tatsuhiko Ozono, Hisatake Matsumoto, Hiroshi Ogura, Keigo Kihara, Hideki Mochizuki, Tatsusada Okuno, Shuhei Sakakibara, Makoto Kinoshita, Daisuke Okuzaki

Frontiers in Immunology　Vol. 14　p. 998233-998233　2023/02/23　Research paper (scientific journal)

Antibody feedback contributes to facilitating the development of Omicron-reactive memory B cells in SARS-CoV-2 mRNA vaccinees

Takeshi Inoue, Ryo Shinnakasu, Chie Kawai, Hiromi Yamamoto, Shuhei Sakakibara, Chikako Ono, Yumi Itoh, Tommy Terooatea, Kazuo Yamashita, Toru Okamoto, Noritaka Hashii, Akiko Ishii-Watabe, Noah S. Butler, Yoshiharu Matsuura, Hisatake Matsumoto, Shinya Otsuka, Kei Hiraoka, Takanori Teshima, Masaaki Murakami, Tomohiro Kurosaki

Journal of Experimental Medicine　Vol. 220　No. 2　2023/02/06　Research paper (scientific journal)

Transcriptional differences between coronavirus disease 2019 and bacterial sepsis.

Hiroshi Ito, Masakazu Ishikawa, Hisatake Matsumoto, Fuminori Sugihara, Daisuke Okuzaki, Haruhiko Hirata, Hiroshi Ogura

Virology journal　Vol. 19　No. 1　p. 198-198　2022/11/28　Research paper (scientific journal)

Combination of WFDC2, CHI3L1, and KRT19 in Plasma Defines a Clinically Useful Molecular Phenotype Associated with Prognosis in Critically Ill COVID-19 Patients.

Takeshi Ebihara, Tsunehiro Matsubara, Yuki Togami, Hisatake Matsumoto, Jotaro Tachino, Hiroshi Matsuura, Takashi Kojima, Fuminori Sugihara, Shigeto Seno, Daisuke Okuzaki, Haruhiko Hirata, Hiroshi Ogura

Journal of clinical immunology　Vol. 43　No. 2　p. 1-13　2022/11/04　Research paper (scientific journal)

Development of clinical phenotypes and biological profiles via proteomic analysis of trauma patients.

Jotaro Tachino, Hisatake Matsumoto, Fuminori Sugihara, Shigeto Seno, Daisuke Okuzaki, Tetsuhisa Kitamura, Sho Komukai, Yoshiyuki Kido, Takashi Kojima, Yuki Togami, Yusuke Katayama, Yuko Nakagawa, Hiroshi Ogura

Critical care (London, England)　Vol. 26　No. 1　p. 241-241　2022/08/06

Clinical Significance of Interferon Signaling Based on mRNA-microRNA Integration and Plasma Protein Analyses in Critically Ill COVID-19 Patients.

Yuki Togami, Hisatake Matsumoto, Jumpei Yoshimura, Tsunehiro Matsubara, Takeshi Ebihara, Hiroshi Matsuura, Yumi Mitsuyama, Takashi Kojima, Masakazu Ishikawa, Fuminori Sugihara, Haruhiko Hirata, Daisuke Okuzaki, Hiroshi Ogura

Molecular therapy. Nucleic acids　Vol. 29　p. 343-353　2022/07/13　Research paper (scientific journal)

The Long Non-Coding Antisense RNA JHDM1D-AS1 Regulates Inflammatory Responses in Human Monocytes

Erik Malmstrom, Hina N. Khan, Cornelis van 't Veer, Melissa Stunnenberg, Mariska T. Meijer, Hisatake Matsumoto, Natasja A. Otto, Teunis B. H. Geijtenbeek, Alex F. de Vos, Tom van der Poll, Brendon P. Scicluna

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY　Vol. 12　p. 934313-934313　2022/07　Research paper (scientific journal)

GROWTH DIFFERENTIATION FACTOR-15 CORRELATES WITH MORTALITY AND SEVERITY IN SEVERE BURNS.

Shinya Onishi, Takeshi Ebihara, Yuki Togami, Tsunehiro Matsubara, Hisatake Matsumoto, Akinori Osuka, Hiroshi Ogura, Jun Oda

Shock (Augusta, Ga.)　Vol. 57　No. 6　p. 211-217　2022/05/26　Research paper (scientific journal)

Anti-nucleocapsid antibodies enhance the production of IL-6 induced by SARS-CoV-2 N protein

Emi E. Nakayama, Ritsuko Kubota-Koketsu, Tadahiro Sasaki, Keita Suzuki, Kazuko Uno, Jun Shimizu, Toru Okamoto, Hisatake Matsumoto, Hiroshi Matsuura, Shoji Hashimoto, Toshio Tanaka, Hiromasa Harada, Masafumi Tomita, Mitsunori Kaneko, Kazuyuki Yoshizaki, Tatsuo Shioda

SCIENTIFIC REPORTS　Vol. 12　No. 1　p. 8108-8108　2022/05　Research paper (scientific journal)

Dynamic change of fecal microbiota and metabolomics in a polymicrobial murine sepsis model

Arisa Muratsu, Mitsunori Ikeda, Kentaro Shimizu, Shoichiro Kameoka, Daisuke Motooka, Shota Nakamura, Hisatake Matsumoto, Hiroshi Ogura, Takeshi Shimazu

ACUTE MEDICINE & SURGERY　Vol. 9　No. 1　2022/01　Research paper (scientific journal)

Role of Myeloid Tet Methylcytosine Dioxygenase 2 in Pulmonary and Peritoneal Inflammation Induced by Lipopolysaccharide and Peritonitis Induced by Escherichia coli

Wanhai Qin, Xanthe Brands, Hisatake Matsumoto, Joe M. Butler, Cornelis Van't Veer, Alex F. de Vos, Joris J. T. H. Roelofs, Brendon P. Scicluna, Tom van der Poll

CELLS　Vol. 11　No. 1　2022/01　Research paper (scientific journal)

Resistin Associated With Cytokines and Endothelial Cell Adhesion Molecules Is Related to Worse Outcome in COVID-19.

Takeshi Ebihara, Hisatake Matsumoto, Tsunehiro Matsubara, Yuki Togami, Shunichiro Nakao, Hiroshi Matsuura, Shinya Onishi, Takashi Kojima, Fuminori Sugihara, Daisuke Okuzaki, Haruhiko Hirata, Hitoshi Yamamura, Hiroshi Ogura

Frontiers in immunology　Vol. 13　p. 830061-830061　2022　Research paper (scientific journal)

Sepsis-Associated Encephalopathy: A Mini-Review of Inflammation in the Brain and Body.

Hiroshi Ito, Sanae Hosomi, Yoshihisa Koyama, Hisatake Matsumoto, Yukio Imamura, Hiroshi Ogura, Jun Oda

Frontiers in aging neuroscience　Vol. 14　p. 912866-912866　2022　Research paper (scientific journal)

HIVEP1 Is a Negative Regulator of NF-kappa B That Inhibits Systemic Inflammation in Sepsis

Hisatake Matsumoto, Brendon P. Scicluna, Kin Ki Jim, Fahimeh Falahi, Wanhai Qin, Berke Gurkan, Erik Malmstrom, Mariska T. Meijer, Joe M. Butler, Hina N. Khan, Tsuyoshi Takagi, Shunsuke Ishii, Marcus J. Schultz, Diederik van de Beek, Alex F. de Vos, Cornelis van 't Veer, Tom van der Poll

FRONTIERS IN IMMUNOLOGY　Vol. 12　p. 744358-744358　2021/11　Research paper (scientific journal)

Adipocytokine Profile Reveals Resistin Forming a Prognostic-Related Cytokine Network in the Acute Phase of Sepsis.

Takeshi Ebihara, Hisatake Matsumoto, Tsunehiro Matsubara, Hiroshi Matsuura, Tomoya Hirose, Kentaro Shimizu, Hiroshi Ogura, Sujin Kang, Toshio Tanaka, Takeshi Shimazu

Shock (Augusta, Ga.)　Vol. 56　No. 5　p. 718-726　2021/11/01　Research paper (scientific journal)

Resistin forms a network with inflammatory cytokines and is associated with prognosis in major burns.

Shinya Onishi, Hiroshi Matsuura, Akinori Osuka, Hisatake Matsumoto, Takeshi Ebihara, Hiroshi Ogura

Burns : journal of the International Society for Burn Injuries　Vol. 48　No. 7　p. 1680-1689　2021/10/27　Research paper (scientific journal)

Bone Marrow-Derived Mononuclear Cell Transplantation Can Reduce Systemic Inflammation and Endothelial Glycocalyx Damage in Sepsis.

Tsunehiro Matsubara, Yutaka Umemura, Hiroshi Ogura, Hiroshi Matsuura, Takeshi Ebihara, Hisatake Matsumoto, Kazuma Yamakawa, Kentarou Shimizu, Hideshi Okada, Takeshi Shimazu

Shock (Augusta, Ga.)　Vol. 56　No. 2　p. 260-267　2021/08/01　Research paper (scientific journal)

Hydrogen Gas Therapy Attenuates Inflammatory Pathway Signaling in Septic Mice.

Hiroshi Matsuura, Hisatake Matsumoto, Daisuke Okuzaki, Kentaro Shimizu, Hiroshi Ogura, Takeshi Ebihara, Tsunehiro Matsubara, Shin-Ichi Hirano, Takeshi Shimazu

The Journal of surgical research　Vol. 263　p. 63-70　2021/07　Research paper (scientific journal)

Reply to Cheng et al.: COVID-19 induces lower extent of cytokines, but damages vascular endothelium by IL-6 signaling.

Sujin Kang, Toshio Tanaka, Hitomi Inoue, Chikako Ono, Shoji Hashimoto, Yoshiyuki Kioi, Hisatake Matsumoto, Hiroshi Matsuura, Tsunehiro Matsubara, Kentaro Shimizu, Hiroshi Ogura, Yoshiharu Matsuura, Tadamitsu Kishimoto

Proceedings of the National Academy of Sciences of the United States of America　Vol. 118　No. 21　2021/05/25　Research paper (scientific journal)

Cytokine Elevation in Severe COVID-19 From Longitudinal Proteomics Analysis: Comparison With Sepsis.

Takeshi Ebihara, Hisatake Matsumoto, Tsunehiro Matsubara, Yuki Togami, Shunichiro Nakao, Hiroshi Matsuura, Takashi Kojima, Fuminori Sugihara, Daisuke Okuzaki, Haruhiko Hirata, Hitoshi Yamamura, Hiroshi Ogura

Frontiers in immunology　Vol. 12　p. 798338-798338　2021　Research paper (scientific journal)

IL-6 trans-signaling induces plasminogen activator inhibitor-1 from vascular endothelial cells in cytokine release syndrome.

Sujin Kang, Toshio Tanaka, Hitomi Inoue, Chikako Ono, Shoji Hashimoto, Yoshiyuki Kioi, Hisatake Matsumoto, Hiroshi Matsuura, Tsunehiro Matsubara, Kentaro Shimizu, Hiroshi Ogura, Yoshiharu Matsuura, Tadamitsu Kishimoto

Proceedings of the National Academy of Sciences of the United States of America　Vol. 117　No. 36　p. 22351-22356　2020/09/08　Research paper (scientific journal)

BONE MARROW-DERIVED MONONUCLEAR CELLS TRANSPLANT CAN REDUCE SYSTEMIC INFLAMMATION AND ENDOTHELIAL DAMAGES IN SEPSIS RATS

Tsunehiro Matsubara, Yutaka Umemura, Hiroshi Matsuura, Takeshi Ebihara, Hisatake Matsumoto, Kazuma Yamakawa, Kentaro Shimizu, Hiroshi Ogura, Takeshi Shimazu

SHOCK　Vol. 53　p. 40-40　2020/06

MOLECULAR HYDROGEN GAS THERAPY ATTENUATE INFLAMMATORY PATHWAY SIGNALING IN SEPTIC MICE: RNA-SEQ ANALYSIS OF MULTIPLE ORGANS

Hiroshi Matsuura, Hisatake Matsumoto, Daisuke Okuzaki, Kentaro Shimizu, Hiroshi Ogura, Takeshi Ebihara, Tsunehiro Matsubara, Takeshi Shimazu

SHOCK　Vol. 53　p. 39-40　2020/06

A follow-up report on the effect of a simplified basic life support training program for non-medical staff working at a university hospital: changes in attitude toward cardiopulmonary resuscitation and automated external defibrillator use through repeat training

Hiroshi Matsuura, Tomohiko Sakai, Yusuke Katayama, Tetsuhisa Kitamura, Tomoya Hirose, Hisatake Matsumoto, Tsunehiro Matsubara, Taku Iwami, Yuji Fujino, Takeshi Shimazu

ACUTE MEDICINE & SURGERY　Vol. 7　No. 1　2020/01　Research paper (scientific journal)

Clinical Importance of a Cytokine Network in Major Burns.

Hiroshi Matsuura, Hisatake Matsumoto, Akinori Osuka, Hiroshi Ogura, Kentaro Shimizu, Sujin Kang, Toshio Tanaka, Masashi Ueyama, Takeshi Shimazu

Shock (Augusta, Ga.)　Vol. 51　No. 2　p. 185-193　2019/02　Research paper (scientific journal)

The clinical importance of a cytokine network in the acute phase of sepsis.

Hisatake Matsumoto, Hiroshi Ogura, Kentaro Shimizu, Mitsunori Ikeda, Tomoya Hirose, Hiroshi Matsuura, Sujin Kang, Kanae Takahashi, Toshio Tanaka, Takeshi Shimazu

Scientific reports　Vol. 8　No. 1　p. 13995-13995　2018/09/18　Research paper (scientific journal)

Glycocalyx Shedding is Enhanced by Age and Correlates with Increased Fluid Requirement in Patients with Major Burns.

Akinori Osuka, Hirofumi Kusuki, Kazuhiro Yoneda, Hiroshi Matsuura, Hisatake Matsumoto, Hiroshi Ogura, Masashi Ueyama

Shock (Augusta, Ga.)　Vol. 50　No. 1　p. 60-65　2018/07　Research paper (scientific journal)

Circulating syndecan-1 predicts the development of disseminated intravascular coagulation in patients with sepsis.

Mitsunori Ikeda, Hisatake Matsumoto, Hiroshi Ogura, Tomoya Hirose, Kentaro Shimizu, Kouji Yamamoto, Ikuro Maruyama, Takeshi Shimazu

Journal of critical care　Vol. 43　p. 48-53　2018/02　Research paper (scientific journal)

Therapeutic Effectiveness of Anti-RAGE Antibody Administration in a Rat Model of Crush Injury.

Hisatake Matsumoto, Naoya Matsumoto, Junya Shimazaki, Junichiro Nakagawa, Yukio Imamura, Kazuma Yamakawa, Tomoki Yamada, Mitsunori Ikeda, Hiroko Hiraike, Hiroshi Ogura, Takeshi Shimazu

Scientific reports　Vol. 7　No. 1　p. 12255-12255　2017/09/25　Research paper (scientific journal)

Clinical Significance of Tissue Factor and CD13 Double-Positive Microparticles in Sirs Patients with Trauma and Severe Sepsis.

Hisatake Matsumoto, Kazuma Yamakawa, Hiroshi Ogura, Taichin Koh, Naoya Matsumoto, Takeshi Shimazu

Shock (Augusta, Ga.)　Vol. 47　No. 4　p. 409-415　2017/04　Research paper (scientific journal)

THE KEY CYTOKINE NETWORK ASSOCIATED WITH THE SEVERITY AND PROGNOSIS IN EXTENSIVE BURN PATIENTS

Hiroshi Matsuura, Hisatake Matsumoto, Akinori Osuka, Hiroshi Ogura, Toshiro Tanaka, Suijin Kang, Takeshi Shimazu

CRITICAL CARE MEDICINE　Vol. 44　No. 12　2016/12

The Beneficial Effects of ETS-GS, a Novel Vitamin E Derivative, on a Rat Model of Crush Injury.

Junichiro Nakagawa, Naoya Matsumoto, Yuko Nakane, Kazuma Yamakawa, Tomoki Yamada, Hisatake Matsumoto, Junya Shimazaki, Yukio Imamura, Hiroshi Ogura, Takashi Jin, Takeshi Shimazu

Shock (Augusta, Ga.)　Vol. 46　No. 6　p. 681-687　2016/12　Research paper (scientific journal)

Effect of Histone Acetylation on N-Methyl-D-Aspartate 2B Receptor Subunits and Interleukin-1 Receptors in Association with Nociception-Related Somatosensory Cortex Dysfunction in a Mouse Model of Sepsis.

Yukio Imamura, Nao Yoshikawa, Yuki Murkami, Satoko Mitani, Naoya Matsumoto, Hisatake Matsumoto, Tomoki Yamada, Kazuma Yamakawa, Junichiro Nakagawa, Hiroshi Ogura, Takeshi Shimazu, Takashi Jin

Shock (Augusta, Ga.)　Vol. 45　No. 6　p. 660-7　2016/06　Research paper (scientific journal)

Effect of lipid emulsion during resuscitation of a patient with cardiac arrest after overdose of chlorpromazine and mirtazapine.

Hisatake Matsumoto, Mitsuo Ohnishi, Ryosuke Takegawa, Tomoya Hirose, Yuji Hattori, Takeshi Shimazu

The American journal of emergency medicine　Vol. 33　No. 10　2015/10　Research paper (scientific journal)

Safe tracheostomy: blunt puncture and dilation after minimal surgical exposure of the trachea (BPAD tracheostomy).

Hisatake Matsumoto, Mitsuo Ohnishi, Akinori Wakai, Tomoya Hirose, Nobuto Mori, Jotaro Tachino, Daikai Sadamitsu, Takeshi Shimazu

Clinical case reports　Vol. 3　No. 10　p. 773-6　2015/10　Research paper (scientific journal)

The risk of pediatric bicycle handlebar injury compared with non-handlebar injury: a retrospective multicenter study in Osaka, Japan.

Tomoya Hirose, Hiroshi Ogura, Takeyuki Kiguchi, Yasuaki Mizushima, Futoshi Kimbara, Junya Shimazaki, Shigeru Shiono, Hitoshi Yamamura, Akinori Wakai, Ryosuke Takegawa, Hisatake Matsumoto, Mitsuo Ohnishi, Takeshi Shimazu

Scandinavian journal of trauma, resuscitation and emergency medicine　Vol. 23　p. 66-66　2015/09/17　Research paper (scientific journal)

Pediatric trauma and the Pediatric Trauma Society: Our time has come

Eileen M. Bulger, Hisatake Matsumoto

JOURNAL OF TRAUMA AND ACUTE CARE SURGERY　Vol. 78　No. 6　p. 1093-1094　2015/06　Research paper (scientific journal)

A reassessment of the impact of trauma systems consultation on regional trauma system development

Hisatake Matsumoto, Naoya Matsumoto, Hiroshi Ogura, Junya Shimazaki, Kazuma Yamakawa, Kouji Yamamoto, Takeshi Shimazu

JOURNAL OF TRAUMA AND ACUTE CARE SURGERY　Vol. 78　No. 6　p. 1086-1093　2015/06　Research paper (scientific journal)

The clinical significance of circulating soluble RAGE in patients with severe sepsis.

Hisatake Matsumoto, Naoya Matsumoto, Hiroshi Ogura, Junya Shimazaki, Kazuma Yamakawa, Kouji Yamamoto, Takeshi Shimazu

The journal of trauma and acute care surgery　Vol. 78　No. 6　p. 1086-93　2015/06　Research paper (scientific journal)

Enhanced expression of cell-specific surface antigens on endothelial microparticles in sepsis-induced disseminated intravascular coagulation.

Hisatake Matsumoto, Kazuma Yamakawa, Hiroshi Ogura, Taichin Koh, Naoya Matsumoto, Takeshi Shimazu

Shock (Augusta, Ga.)　Vol. 43　No. 5　p. 443-9　2015/05　Research paper (scientific journal)

Fulminant phlegmonitis of the esophagus, stomach, and duodenum due to Bacillus thuringiensis.

Hisatake Matsumoto, Hiroshi Ogura, Masafumi Seki, Mitsuo Ohnishi, Takeshi Shimazu

World journal of gastroenterology　Vol. 21　No. 12　p. 3741-5　2015/03/28　Research paper (scientific journal)

SURVIVAL IMPROVEMENT BY ANTI-RAGE ANTIBODY ADMINISTRATION IN A RAT MODEL OF CRUSH INJURY

Hisatake Matsumoto, Naoya Matsumoto, Junya Shimazaki, Junichiro Nakagawa, Kazuma Yamakawa, Tomoki Yamada, Hiroshi Ogura, Takeshi Shimazu

CRITICAL CARE MEDICINE　Vol. 42　No. 12　2014/12

EVALUATION OF ENDOTHELIAL MICROPARTICLES IN SEPSIS INDUCED DIC TREATED BY RECOMBINANT THROMBOMODULIN

Hiroki Takahashi, Hisatake Matsumoto, Hiroshi Ogura, Kazuma Yamakawa, Taichin Koh, Naoya Matsumoto, Takeshi Shimazu

CRITICAL CARE MEDICINE　Vol. 42　No. 12　2014/12

Effectiveness of a simplified cardiopulmonary resuscitation training program for the non-medical staff of a university hospital.

Tomoya Hirose, Taku Iwami, Hiroshi Ogura, Hisatake Matsumoto, Tomohiko Sakai, Kouji Yamamoto, Toshiaki Mano, Yuji Fujino, Takeshi Shimazu

Scandinavian journal of trauma, resuscitation and emergency medicine　Vol. 22　p. 31-31　2014/05/10　Research paper (scientific journal)

A case of Fournier gangrene caused by Candida glabrata

Matsumoto Hisatake, Nishimura Tetsuro, Ohnishi Mitsuo, Wakai Akinori, Sadamitsu Daikai

Nihon Kyukyu Igakukai Zasshi　Vol. 25　No. 2　p. 43-49　2014/02

Transplantation of bone marrow-derived mononuclear cells can improve the survival rate and suppress the inflammatory response in a rat crush injury model

J Nakagawa, N Matsumoto, K Yamakawa, T Yamada, H Matsumoto, T Muroya, H Ogura, T Shimazu

Critical Care　Vol. 18　No. Suppl 1　p. P65-P65　2014　Research paper (scientific journal)

Simplified Cardiopulmonary Resuscitation Training Program for the Non-Medical Staffs Working at a University Hospital Improved the Quality of Chest Compression, but Maintenance of the Skill Required Repeated Attendance

Tomoya Hirose, Taku Iwami, Hiroshi Ogura, Hisatake Matsumoto, Yasuaki Kido, Keiko Seo, Kouji Yamamoto, Toshiaki Mano, Yuji Fujino, Takeshi Shimazu

CIRCULATION　Vol. 128　No. 22　2013/11

Primary Torsion of the Greater Omentum: A Case Report

Matsumoto Hisatake, Mizuno Shinichi, Hibino Masayuki, Nishigaki Eiji, Fujieda Hironori, Tamauchi Toshio

Nihon Fukubu Kyukyu Igakkai Zasshi (Journal of Abdominal Emergency Medicine)　Vol. 32　No. 7　p. 1247-1250　2012/11

Incidence and outcomes of out-of-hospital cardiac arrest with shock-resistant ventricular fibrillation: Data from a large population-based cohort.

Tomohiko Sakai, Taku Iwami, Osamu Tasaki, Takashi Kawamura, Yasuyuki Hayashi, Hiroshi Rinka, Yasuo Ohishi, Tomoyoshi Mohri, Masafumi Kishimoto, Tatsuya Nishiuchi, Kentaro Kajino, Hisatake Matsumoto, Toshifumi Uejima, Masahiko Nitta, Chizuka Shiokawa, Hisashi Ikeuchi, Atsushi Hiraide, Hisashi Sugimoto, Yasuyuki Kuwagata

Resuscitation　Vol. 81　No. 8　p. 956-61　2010/08　Research paper (scientific journal)